165 Sentences With "occlude" | Random Sentence Generator

And yet yesterday's good deeds remain good even if today's bad ones occlude them.

Like many geeks, I have a piece of opaque tape to occlude my Chromebook's camera.

In response, a whole industry has built up to help occlude and conceal hacking tools.

And it reminds viewers to doubt generalisations about history that occlude the experiences and complexities of individuals.

Either way, such images are usually kept classified in order to occlude US intelligence gathering methods and capabilities.

This is a difficult task when foreground elements occlude significant portions of the video, as in the example below.

Flat-earthism has not entirely disappeared, despite the achievement of science, and sophisticated forms of denial still occlude the atmosphere.

Seen from afar, Earth would occlude just 84 parts per million of the sun's light — less than one hundredth of a percent.

That classical, very consistent taste (which critics would term "narrow") can occlude how surprising, open and deeply unusual his criticism can be.

We've seen smartwatches with physical hands before, and one of the problems is that those hands occlude the information on the watchface.

The blockade of the legislature — a clear violation of the Constitution — shows once again how diarchy can occlude legitimate sources of democratic power.

Without a light source positioned directly below or on the side, your phone's shadow tends to occlude whatever it is you're trying to photograph.

That news — negative and intense though it is — can easily occlude the many positive, longer term stories that are fundamental drivers of the world.

Where client meetings didn't overtake time with family and friends, and the messy business of personal livelihood didn't occlude all manner of professional success.

Despite the fact that we occlude our faces with our hands regularly, very little research has been done on performing facial recognition with hand occlusion.

Straddling the highway to Jaipur, the town of 30,000 people is dense with two- and three-story concrete buildings that occlude any sense of the landscape.

He confided to me on another night that like so many people he has tried to hire, he knows that working for Breitbart will occlude his future.

Trump's offenses against basic decency burn so hot and so proximate that they occlude distant liberal complaints about Romney the way sunlight makes the stars invisible until nightfall.

A long-standing flaw of bottom-firing speakers of this kind is also that you can occlude their opening really easily, especially when holding the phone in landscape for gaming.

The more powerful headsets must be tethered by thick cables to PCs or consoles, which can tangle up players' legs when these rigs occlude their view of the real world.

It's just that in the US, those subjects have tended to occlude deeper and more urgent considerations (like justice) and exclude a wide range of policy instruments (like public investment).

Instead of just admitting that her family is a mess, Palin exhibited Trump-like swagger, conjuring a story in an attempt to gin up the crowd and occlude her son's behavior.

He shows the power of one's own mind to occlude what one has witnessed, especially when it is a key to understanding something important—something that you have forgotten to remember.

The pictures, usually taken in cities, occlude urban chaos, so that tight compositions offer a full sense of the solitude and emotion that one senses Mr. Heath must have also felt profoundly.

It could also lead to further investigation into allegations that Bloomberg has mistreated a number of women — as well as what a number of nondisclosure statements former female employees have signed occlude.

Given that the Ukraine whistleblower shared information that led to the president's impeachment, future hesitancy to be a whistleblower could very well occlude serious crimes or abuses of power, removing an important check on lawmakers.

I've had no accidental degradation in signal quality or stability, and it's only when I really occlude the entire rear window with a close (and unnatural) grip in my palm that I can disconnect the Pixel 2.

They may lust for furtive, late-night sexual encounters with a "buddy" or find themselves intensely admiring a male porn star's biceps, but this does not occlude their love for their wives and girlfriends, nor women in general.

To the degree that Trump has any ideology at all, it's a hatred of civility—a belief that the normal decencies painfully evolved over centuries are signs of weakness which occlude the natural order of domination and submission.

Each whiteboard gets its own little short code that you can share with anybody to make it easier to join the meeting, and you can move around and resize the video chat windows so they don't occlude the whiteboard itself.

The fast way happens as a series of lurches: eyes occlude, hearing dwindles, a hand trembles where it hadn't, a hip breaks—the usually hale and hearty doctor's murmur in the yearly checkup, There are some signs here that concern me .

Context: JPMorgan and the International Monetary Fund have recently warned of existential threats from climate change, but the Trump administration has tried to occlude the issue, and Mr. Mnuchin recently made headlines by mocking Greta Thunberg, the teenage climate activist.

He sings about the perils of global warming, and bemoans the ways we let smaller problems occlude existential threats, all the while he and drummer Alex Audette and bassist Michael Geacone churn out #riffs that that chime and grind in equal measure.

But English deals with the inconsistencies in a transparent way — even if a bit late in the game — and, curiously, it even fits perfectly into the ongoing narrative of Timbuktu, a place where the magnificence of the tale can occlude the plain facts of what's there.

As she is taken away in an ambulance, he briefly puts his hand in front of his face, to occlude his final sight of her, much as Tom Hanks gazes up from Earth, in "Apollo 13" (1995), and uses his thumb to blot out the moon he will never reach.

From crafting her very first dress as a child from potato sacks, to the aforementioned composite couture, to starting her own label in defiance of all around her, especially from Yves St. Laurent, who worried she'd end up suffering as he did, de Ribes's title does not occlude her work ethic.

The complete cohesion of all these elements is evident even in the structure of the shot itself: Michell strategically uses scenery as William is walking through Notting Hill's Portobello Road marketplace to effectively occlude our awareness that different shots have been edited together to create the appearance of a single long take.

The exhibition prominently features Walker's controversial appropriations of images of black people and photographs from the Civil Rights movement, in which he smears toothpaste and other commercial materials on the images to occlude their content, and has been met with a well-documented boycott from St. Louis artists and widespread denunciations of the curatorial choices.

"It's our attempt to convince as many people who either may not have yet known about the eclipse or haven't made plans, that this event is so magical and awe inspiring that they need to figure out a way to get into the path of totality," Mr. Silverstein said, using the term for the regions for which the moon's shadow will occlude the sun completely.

Non-balanced occlusion is seen when teeth do not occlude in simultaneous contacts. Both concepts will be explored in greater detail in the following article.

Ruptures of the fibrous cap expose thrombogenic material, such as collagen, to the circulation and eventually induce thrombus formation in the lumen. Upon formation, intraluminal thrombi can occlude arteries outright (e.g., coronary occlusion), but more often they detach, move into the circulation, and eventually occlude smaller downstream branches causing thromboembolism. Apart from thromboembolism, chronically expanding atherosclerotic lesions can cause complete closure of the lumen.

Therefore, its possible for the cilio retinal artery itself to occlude causing significant visual loss in the perfused macula region (surrounding visual field will remain intact).

Medications, such as antihistamines and antidepressants, can also impair salivary flow. Stimulants, most notoriously methylamphetamine, also occlude the flow of saliva to an extreme degree. This is known as meth mouth.

Philadelphia: W.B. Saunders Company, 2002. page 192. When that change has a negative effect on how the teeth occlude, this may cause tenderness, pain, and damage to or movement of the teeth.

Though relatively the same, there are some minor differences between the deciduous (baby) maxillary lateral incisor and that of the permanent maxillary lateral incisor. The maxillary lateral incisors occlude in opposition to the mandibular lateral incisors.

The illusion works even when the small squares completely occlude the blue cross (see fig. 3). In conclusion, there isn’t always correlation between the size of the surrounding shapes and the relative size perception of the test shape.

In the Class II Division 2 incisal classification of malocclusion, the lower incisors occlude posterior to the cingulum plateau of the upper incisors and the upper central incisors are retroclined. The overjet is usually minimal but it may be increased.

If the distended cells occlude the vasculature, focal areas of ischemic necrosis may be evident within various organs. It has been suggested by some researchers that the hypertrophied cells are some type of leukocyte, which is consistent with their tissue distribution.

They do not look like typical mammalian teeth, which do occlude precisely and have distinct cingula and cusps offset from a single longitudinal row. Indeed, precise occlusion is thought to have evolved very early in the evolution of mammals, in Morganucodon itself.

In atherosclerosis, a severe disease in modern society, coronary blood vessels occlude. These vessels have to be freed and held open i.e. by stents. Unfortunately after certain time these vessels close again and have to be bypassed to allow for upkeep of circulation.

Parti-colored Tibetan Spaniel The Tibetan Spaniel has a domed head that is small in comparison to its body. It has a short blunt muzzle, free of wrinkles. Its teeth occlude in either an underbite or an end-to-end bite. The nose is black.

Alekhin is scheduled to occlude a 9.1 magnitude star in the Leo constellation on 30 November 2008, dimming the magnitude of both heavenly bodies for a maximum duration of 0.6 seconds. Astronomers had, as of March 2008, not predicted an optimal trajectory for the event.

The illusion works even when the small squares completely occlude the blue cross (see fig. 1.c). In conclusion, there isn’t always correlation between the size of the surrounding shapes and the relative size perception of the test shape. In fig. 2.a and 2.

Kv1.3 has been reported to be expressed in the inner mitochondrial membrane in lymphocytes. The apoptotic protein Bax has been suggested to insert into the outer mitochondrial membrane and occlude the pore of Kv1.3 via a lysine residue. Thus, Kv1.3 modulation may be one of many mechanisms that contribute to apoptosis.

One approach used for treatment is embolization. A six-vessel angiogram is employed to determine the vascular supply to the fistula. Detachable coils, liquid embolic agents like NBCA, and onyx, or combinations of both are injected into the blood vessel to occlude the DAVF. Preoperative embolization can also be used to supplement surgery.

After it closes, the remnant is known as ligamentum venosum. If the ductus venosus fails to occlude after birth, it remains patent (open), and the individual is said to have a patent ductus venosus and thus an intrahepatic portosystemic shunt (PSS). This condition is hereditary in some dog breeds (e.g. Irish Wolfhound).

Therefore, treatment of chyle fistulae relies upon either decreased production of lymphatic fluid to allow for healing of lymphatic defect(s) or permanent diversion of lymphatic fluid away from lymphatic defect(s). Decreased production of lymphatic fluid may be accomplished by dietary restriction (or complete replacement of oral intake with total parenteral nutrition), as well as by the medications octreotide (a synthetic analogue of the hormone somatostatin) and orlistat (a lipase inhibitor that decreases absorption of dietary fats). Permanent diversion of lymphatic fluid may be accomplished by thoracic duct embolization (a needle- based procedure to occlude the duct by depositing glue/embolic material into it) or by thoracic duct ligation (an open surgical procedure to occlude the duct by suturing tightly around it).

Callus is extending over the umbilicus so as to occlude it completely, giving a shape of oblique columellar end. The height of the shell is 30 mm. The width of the shell is 33 mm. The operculum is small, round, horny, thin, translucent, marked with a fine spiral line which coils about 13 in number.

The test is done by applying a tourniquet at the level of the sapheno- femoral junction to occlude the superficial pathway, and then the patient is asked to move in situ. If the deep veins are occluded, the dilated veins increase in prominence. This is a more objective test as it does not depend on patient's pain threshold.

Pulp stones can be classified based on different location and structure. Based on location, they can classified into free, embedded and adherent pulp stones. Free pulp stones are found within the pulp tissue and is the most common encounter. The size vary from 50μm in diameter to several millimetres and may occlude the entire pulp chamber.

University of Rochester physics professor John Howell and graduate student Joseph Choi have announced a scalable cloaking device which uses common optical lenses to achieve visible light cloaking on the macroscopic scale, known as the "Rochester Cloak". The device consists of a series of four lenses which direct light rays around objects which would otherwise occlude the optical pathway.

The odontoid may have been encased in a keratinous covering so that it could occlude with the teeth. Apart from the skull, the skeleton of Istiodactylus was similar to those of other ornithocheiroid pterosaurs. The vertebral column, forelimb, and trunk bones were pneumatised by air sacs. The neural arches of the vertebrae had tall, sloping laminae.

Embolization is a minimally invasive technique used in EVTM of selected hemodynamically unstable patients with both traumatic and non-traumatic injuries. It is the artificial creation of a thrombus by the introduction of various substances to intentionally occlude a vessel with the aim to stop or diminish blood extravasation and is a critical part of the modern management of arterial injuries.

Sinoconodon is known only from the skull and lower jaws. It is younger geologically than some Morganucodon, but Sinoconodon has many features which are more primitive than Morganucodon. Particularly significant is the dentition of Sinoconodon, in which the postcanine tooth row consists of five multicuspid trenchant teeth with only the vestiges of cingula. These teeth do not precisely occlude with one another.

Manner features: The features that specify the manner of articulation. #[+/− continuant] This feature describes the passage of air through the vocal tract. [+cont] segments are produced without any significant obstruction in the tract, allowing air to pass through in a continuous stream. [−cont] segments, on the other hand, have such an obstruction, and so occlude the air flow at some point of articulation.

A stable hairpin (left) unwinds at a higher temperature (right). The highlighted Shine-Dalgarno sequence becomes exposed, allowing the binding of the 30S ribosomal subunit. RNA thermometers are found in the 5′ UTR of messenger RNA, upstream of a protein-coding gene. Here they are able to occlude the ribosome binding site (RBS) and prevent translation of the mRNA into protein.

Fibrinogen (factor I) is a glycoprotein complex, made in the liver, that circulates in the blood of all vertebrates. During tissue and vascular injury, it is converted enzymatically by thrombin to fibrin and then to a fibrin-based blood clot. Fibrin clots function primarily to occlude blood vessels to stop bleeding. Fibrin also binds and reduces the activity of thrombin.

However, what this method may have been is unclear. The premaxillary teeth do not show wear facets and did not occlude with the teeth of the lower jaw, indicating that they were not used in any abrasive activities and could not have been used to grip prey. The snout tip did not have the pressure receptors present in crocodilians and Spinosaurus.

The teeth of the upper and lower jaw contain bump rows that fit together perfectly in order to maintain an accurate bite. Oligokyphus had a face similar to that of modern mammals, although there were differences in the cheekbones and eye sockets. It had a bony secondary palate and double-rooted cheek teeth. Unlike mammals, the teeth of Oligokyphus did not occlude.

There is no evidence of the spread of the pathogen through insect vectors or seeds. The propagation of willows vegetatively reveal infection in young (one to three years old) willow trees, suggesting the pathogen can survive latently in propagating material. After emerging from its latent phase, branches will wilt and turn reddish-brown as the bacteria colonize the xylem. Bacterial colonies occlude xylem vessels, impeding circulation.

The original test proposed by Allen is performed as follows: # The patient is asked to clench both fists tightly for 1 minute at the same time. #Pressure is applied over both radial arteries simultaneously so as to occlude them. # The patient then opens the fingers of both hands rapidly, and the examiner compares the colour of both. The initial pallor should be replaced quickly by rubor.

In the modified Allen test, one hand is examined at a time: # The hand is elevated and the patient is asked to clench their fist for about 30 seconds. # Pressure is applied over the ulnar and the radial arteries so as to occlude both of them. # Still elevated, the hand is then opened. It should appear blanched (pallor may be observed at the finger nails).

The teeth look much more natural and are much longer lasting than cold cured or temporary dentures. In many cases, they may be tried out before they are finished to ensure that all the teeth occlude (meet) properly and look esthetically pleasing. These usually come with a 90-day to two-year warranty and in some cases a money-back guarantee if the customer is not satisfied.

This occlusal scheme was first described by Dr. M. M. DeVan in 1951. Monoplane occlusion involves having non-anatomic denture teeth with a 0˚ incisal guidance angle, arranged on a flat occlusal plane. As a consequence, when patients with monoplane occlusion occlude anteriorly, an interocclusal gap appears posteriorly. This is termed the 'Christensen phenomenon' and forms the basis for categorising monoplane occlusion as non- balanced.

This may eventually grow or rupture to occlude the arteries. It is also a risk factor for acute coronary syndromes, which are diseases that are characterised by a sudden deficit of oxygenated blood to the heart tissue. Atherosclerosis is also associated with problems such as aneurysm formation or splitting ("dissection") of arteries. Another major cardiovascular disease involves the creation of a clot, called a "thrombus".

Riboswitches have been found to act as regulators of gene expression, particularly in bacteria, but also in plants and archaea. Riboswitches alter their secondary structure in response to the binding of a metabolite. This change in structure can result in the formation or disruption of a terminator, truncating or permitting transcription respectively. Alternatively, riboswitches may bind or occlude the Shine–Dalgarno sequence, affecting translation.

One person died and 59 people were injured. The series of events that occurred as the tornado moved past the Hesston area were most interesting. Eyewitness accounts observed the touchdown of an additional tornado just to the north. This is consistent with models of what is known as a "tornado handoff", in which an old mesocyclone and tornado occlude as a new mesocyclone and tornado further downwind becomes dominant.

Some genera, such as Yacarerani and Pakasuchus, have extremely mammal-like teeth. Their molars are complex and multicuspid, and are able to occlude or fit with one another. Some forms such as Malawisuchus had jaw joints that enabled them to move the jaw back and forth in a shearing motion rather than just up and down. A derived group of notosuchians, the baurusuchids differ considerably from other forms.

Dental attrition is tooth wear caused by tooth to tooth contact. Well-defined wear facets appear on tooth cusps or ridges. This can be caused by several factors, including parafunctional habits such as bruxism or clenching, developmental defects, hard or rough-textured diet, and absence of posterior teeth support. If the natural teeth oppose or occlude with porcelain restorations, then accelerated attrition of the natural teeth may result.

If a bilaterally symmetrical ancestor were to become affixed by its right hand side, it would occlude all features on that side. When that organism wanted to become secondarily bilaterally symmetrical again, it would be forced to resculpt its new left and right hand sides from the old left hand side. The end result is a bilaterally symmetrical animal, but with its dorsoventral axis rotated a quarter of a turn.

Usually autologous vessels from the patient or synthetic polymer grafts are used for this purpose. Both options have disadvantages. Firstly there are only few autologous vessels available in a human body that might be of low quality, considering the health status of the patient. The synthetic polymer based grafts on the other hand often have insufficient haemocompatibility and thus rapidly occlude - a problem that is especially prone in small calibre grafts.

Sok RNA then indirectly inhibits the translation of hok by inhibiting mok translation. There is a complementary region where sok transcript binds hok mRNA directly (pictured), but it does not occlude the Shine-Dalgarno sequence. Instead, sok RNA regulates the translation of the mok open reading frame, which nearly entirely overlaps that of hok. It is this translation-coupling which effectively allows sok RNA to repress the translation of hok mRNA.

Mayfield and Drake aneurysm clips ready for implantation. Emergency treatment for individuals with a ruptured cerebral aneurysm generally includes restoring deteriorating respiration and reducing intracranial pressure. Currently there are two treatment options for securing intracranial aneurysms: surgical clipping or endovascular coiling. If possible, either surgical clipping or endovascular coiling is typically performed within the first 24 hours after bleeding to occlude the ruptured aneurysm and reduce the risk of rebleeding.

The interatrial septum forms during the first and second months of fetal development. Formation of the septum occurs in several stages. The first is the development of the septum primum, a crescent-shaped piece of tissue forming the initial divider between the right and left atria. Because of its crescent shape, the septum primum does not fully occlude the space between the left and right atria; the opening that remains is called the ostium primum.

Researchers stress that the presence or absence of a hymen is not a reliable indicator of whether or not a female has been vaginally penetrated. The hymen is a thin film of membrane situated just inside the vulva which can partially occlude the entrance to the vaginal canal. It is flexible and can be stretched or torn during first engagement in vaginal intercourse. However, a hymen may also be broken during physical activity.

In addition to having ordinary radioles, some Canalipalpata possess one or more highly modified radioles located on the dorsal part of the head. This specialized structure is called an operculum. The operculum is a cone- shaped cartilaginous structure located at the distal end of a long cartilaginous stalk. When threatened or disturbed, the animal withdraws rapidly into its protective calcareous tube and employs the operculum as a plug to occlude the entrance to the tube.

These refractory ores require pre-treatment in order for cyanidation to be effective in recovery of the gold. A refractory ore generally contains sulfide minerals, organic carbon, or both. Sulfide minerals are impermeable minerals that occlude gold particles, making it difficult for the leach solution to form a complex with the gold. Organic carbon present in gold ore may adsorb dissolved gold-cyanide complexes in much the same way as activated carbon.

The catalytic cycle of the reaction catalyzed by DHFR incorporates five important intermediate: holoenzyme (E:NADPH), Michaelis complex (E:NADPH:DHF), ternary product complex (E:NADP+:THF), tetrahydrofolate binary complex (E:THF), and THF‚NADPH complex (E:NADPH:THF). The product (THF) dissociation step from E:NADPH:THF to E:NADPH is the rate determining step during steady-state turnover. Conformational changes are critical in DHFR's catalytic mechanism. The Met20 loop of DHFR is able to open, close or occlude the active site.

It has an autoinhibitory insert that interrupts its activity called an X-Y linker. The X-Y linker has been shown to occlude the active site, and with its removal PLC is activated. The genes encoding alpha-toxin (Clostridium perfringens), Bacillus cereus PLC (BC-PLC), and PLCs from Clostridium bifermentans and Listeria monocytogenes have been isolated and nucleotides sequenced. There is significant homology of the sequences, approximately 250 residues, from the N-terminus.

Transarterial bland embolization (TAE, also known as HAE) is a catheter-based tumor treatment of the liver. In this procedure, a variety of embolizing agents (e.g., polyvinyl alcohol, gelfoam, acrylic copolymer gelatin particles, embospheres) can be delivered through the tumor’s feeding artery in order to completely occlude the tumor’s blood supply. The anti-tumor effects are solely based on tumor ischemia and infarction of tumor tissue, as no chemotherapeutic agents are administered.

Surgical treatment is best, when it can be performed. Pressure within the portal vein is measured as the shunt is closed, and it must be kept below 20 cm H2O or else portal hypertension will ensue. Methods of shunt attenuation should aim to slowly occlude the vessel over several weeks to months in order to avoid complications associated with portal hypertension. These methods include ameroid ring constrictors, cellophane banding, intravascular or percutaneous silicone hydraulic occluders.

Extratropical cyclones begin as waves in large regions of enhanced mid-latitude temperature contrasts called baroclinic zones. These zones contract and form weather fronts as the cyclonic circulation closes and intensifies. Later in their life cycle, extratropical cyclones occlude as cold air masses undercut the warmer air and become cold core systems. A cyclone's track is guided over the course of its 2 to 6 day life cycle by the steering flow of the subtropical jet stream.

The Pro Caecina is a public speech made by Marcus Tullius Cicero on behalf of his friend Aulus Caecina sometime between 71 BC and 69 BC. The speech was delivered in the third hearing of a lawsuit where Caecina averred that he had been unlawfully dispossessed of a farm by use of force. Known for its refinement and scathing characterisations of the opposing parties, the speech is a good study in how rhetorical advocacy can occlude legal argument.

Treatment of hemosuccus pancreaticus depends on the source of the hemorrhage. If the bleeding is identified on angiography to be coming from a vessel that is small enough to occlude, embolization through angiography may stop the bleeding. Both coils in the end-artery and stents across the area of bleeding have been used to control the hemorrhage. However, the bleeding may be refractory to the embolization, which would necessitate surgery to remove the pancreas at the source of hemorrhage.

Ichthyoconodon and Dyskritodon amazighi are the only Mesozoic mammals so far to have been suggested to have possibly foraged in the sea. Researchers such as Zofia Kielan-Jaworowska pointed out lack of functional comparison between eutriconodont teeth and those of marine mammals. Unlike the teeth of seals and cetaceans, eutriconodont molars occlude, creating a shearing motion like carnassials, and unlike the grasping function of marine mammal molars.Zofia Kielan-Jaworowska, Richard L. Cifelli, Zhe-Xi Luo (2004).

This can be overcome with related techniques that allow chaining commands in one single gesture through submenus. However, using interaction techniques that are not pointer-based have proven problematic with both pie and linear menus for cluttered digital tabletop, where physical objects might occlude menu items. Pie menus are unavailable as standard graphical control element in common commercial toolkits. Video games often require custom widget development, so pie menu cost is lower in that particular scenario.

When the teeth are biting down, the maxillary central incisors occlude with the mandibular central and lateral incisors. The contact point of the mandibular teeth is in the lingual fossa of the maxillary central incisor about 4 mm gingivally from the incisal edge. In this position, the maxillary incisors cover nearly half of the mandibular incisors' crowns. When the maxillary and mandibular incisors do not contact even when the mouth is fully closed, an anterior open bite occurs.

Leeway space is the size differential between the primary posterior teeth (C,D,E) and the permanent teeth (canine, first and second pre-molar). Maxillary space of 1.5mm, mandibular 2.5mm can be seen. (Institute of Dentistry, Aberdeen University) As the primary (baby) teeth begin to erupt at 6 months of age, the maxillary and mandibular teeth aim to occlude with one another. The erupting teeth are moulded into position by the tongue, the cheeks and lips during development.

The galaxy has an abundance of ionized hydrogen regions along its spiral arms where stars are forming. These regions appear red in the picture. It also has many dark lanes of dust that occlude its complete starlight. The discovery of NGC134 is often attributed to Sir John Herschel at the Cape of Good Hope, but he did note that it might have been the 590th object discovered by James Dunlop in his 1828 publication, six years prior to Herschel's own observations.

As the cyclone strengthens, the cold front sweeps towards the equator and moves around the back of the cyclone. Meanwhile, its associated warm front progresses more slowly, as the cooler air ahead of the system is denser, and therefore more difficult to dislodge. Later, the cyclones occlude as the poleward portion of the cold front overtakes a section of the warm front, forcing a tongue, or trowal, of warm air aloft. Eventually, the cyclone will become barotropically cold and begin to weaken.

Earwax, also known as cerumen, is a yellowish, waxy substance secreted in the ear canals. It plays an important role in the human ear canal, assisting in cleaning and lubrication, and also provides some protection from bacteria, fungi, and insects. Excess or impacted cerumen can press against the eardrum and/or occlude the external auditory canal and impair hearing, causing conductive hearing loss. If left untreated, cerumen impaction can also increase the risk of developing an infection within the ear canal.

The mesentery is a thin sheet attached to the entire length of intestine, enclosing blood vessels, lymph nodes, and nerves. Occasionally, a small rent (hole) can form in the mesentery, through which a segment of bowel can occasionally enter. As in epiploic foramen entrapment, the bowel first enlarges, since arteries do not occlude as easily as veins, which causes edema (fluid buildup). As the bowel enlarges, it becomes less and less likely to be able to exit the site of entrapment.

Potassium channel blockers inhibit the flow of potassium ions through the channel. They either compete with potassium binding within the selectivity filter or bind outside the filter to occlude ion conduction. An example of one of these competitors is quaternary ammonium ions, which bind at the extracellular face or central cavity of the channel. For blocking from the central cavity quaternary ammonium ions are also known as open channel blockers, as binding classically requires the prior opening of the cytoplasmic gate.

Deprivation amblyopia (amblyopia ex anopsia) results when the ocular media become opaque, such as is the case with congenital cataract or corneal haziness. These opacities prevent adequate visual input from reaching the eye, and disrupt development. If not treated in a timely fashion, amblyopia may persist even after the cause of the opacity is removed. Sometimes, drooping of the eyelid (ptosis) or some other problem causes the upper eyelid to physically occlude a child's vision, which may cause amblyopia quickly.

SAM-binding was confirmed using equilibrium dialysis. The riboswitch has been characterised as a 'tandem riboswitch' - it is able to regulate both translation and transcription. When SAM is present in high concentration, SAM-II will bind its ligand and form a terminator stem to halt transcription. If SAM exists in lower concentrations, SAM-V will be transcribed and, if SAM concentration should then increase, it can bind SAM and occlude the Shine-Dalgarno sequence of the downstream open reading frame.

The radial pulse is commonly measured using three fingers. This has a reason: the finger closest to the heart is used to occlude the pulse pressure, the middle finger is used get a crude estimate of the blood pressure, and the finger most distal to the heart (usually the ring finger) is used to nullify the effect of the ulnar pulse as the two arteries are connected via the palmar arches (superficial and deep). The study of the pulse is known as sphygmology.

An illusory contour is a perceived contour without the presence of a physical gradient. In examples where a white shape appears to occlude black objects on a white background, the white shape appears to be brighter than the background, and the edges of this shape produce the illusory contours. These illusory contours are processed by the brain in a similar way as real contours. The visual system accomplishes this by making inferences beyond the information that is presented in much the same way as the luminance gradient.

Positioning involves bringing the axes of the mouth, pharynx, and larynx into alignment, leading to what's called the "sniffing" position. The sniffing position can be achieved by placing a rolled towel underneath the head and neck, effectively extending the head and flexing the neck. You are at proper alignment when the ear is inline with the sternum. As described by Brian Arthur Sellick in 1961, cricoid pressure (alternatively known as Sellick's maneuver) may be used to occlude the esophagus with the goal of preventing aspiration.

In order to have figures in one exposure actually move in front of a substituted background in the other, a travelling matte was needed, to occlude the correct portion of the background in each frame. In 1918 Frank Williams patented a travelling matte technique, again based on using a black background. This was used in many films, such as The Invisible Man. In the 1920s, Walt Disney used a white backdrop to include human actors with cartoon characters and backgrounds in his Alice Comedies.

Robertia has a short secondary palate, with the choana anterior and at the same level as the tusks. The dentary shelf does not protrude as much as in Emydops, and the concave dentary tables hold five to six pointed teeth medially. Robertia is one of the pylaecephalids with the most dentary teeth, which occlude with the palatine pad (a ridged region posterolateral to the main secondary palate) upon jaw retraction. A beak is located anterior to the tusks and the outer side of the dentary.

However, in patients with large deviations, the thickness of the prism required may reduce vision so much that binocularity is not achievable. In such cases it may be more appropriate simply to occlude one eye temporarily. Occlusion would never be used in infants though both because of the risk of inducing stimulus deprivation amblyopia and because they do not experience diplopia. Other management options at this initial stage include the use of botulinum toxin, which is injected into the ipsilateral medial rectus (botulinum toxin therapy of strabismus).

Tooth contact involved in guidance is particularly important as these occlude a vast number of times per day and so need to be able to resist both heavy and non-axial occlusal loads. When restoring the anterior guidance system should be compatible with the posterior guidance system. This means that excessive strain should not be applied on the posterior guidance system which is limited by the ligametous structures. Upon restoration of the occlusal surfaces of teeth, it is likely to change the occlusion and therefore guidance systems.

The action of this muscle is peculiar. (1) It is, like other muscles, always in a state of tonic contraction, and having no antagonistic muscle it keeps the anal canal and orifice shut. (2) It can be put into a condition of greater contraction under the influence of the will, so as more firmly to occlude the anal aperture, in expiratory efforts unconnected with defecation. (3) Taking its fixed point at the coccyx, it helps to fix the central point of the perineum, so that the bulbospongiosus muscle may act from this fixed point.

Typically the blood pressure obtained via palpation is around 10 mmHg lower than the pressure obtained via auscultation. In general, the examiner can avoid being confused by an auscultatory gap by always inflating a blood pressure cuff to 20-40 mmHg higher than the pressure required to occlude the brachial pulse. There is evidence that auscultatory gaps are related to carotid atherosclerosis and to increased arterial stiffness in hypertensive patients, independent of age. Another cause is believed to be venous congestion within the limb that is being used for the measurement.

As a means of avoiding invasive methods, early endovascular interventions involved the usage of detachable and nondetachable balloon catheters to occlude the aneurysm while preserving the parent artery. Despite the innovative approach, the aneurysms were often found to adapt to the shape of the balloon itself resulting in higher incidents of aneurysm rupture. This procedure was deemed "uncontrollable" due to its high morbidity and mortality rate, but it demonstrated that the endovascular approach was feasible for many aneurysms. Endovascular coils would later be used in 1989 by Hilal et al.

Pulp stones are discrete calcifications found in the pulp chamber of the tooth which may undergo changes to become diffuse pulp calcifications such as dystrophic calcification. They are usually noticed by radiographic examination and appeared as round or ovoid radiopaque lesions. Clinically, a tooth with a pulp stone has normal appearance like any other tooth. The number of pulp stones in a single tooth may vary from 1 to 12 or more, with varying sizes from minute particles to large masses which tend to occlude the pulpal space.

Strontium based toothpastes (acetate and chloride) are therefore able to replace some of the lost calcium and block the exposed tubules in the dentinal tissue. This helps prevent the movement of the fluid within the tubules in response to a sensitivity stimulus that could otherwise cause tooth pain. Some Sensodyne products contain calcium sodium phosphosilicate CSPS (Novamin), which appears to help with tooth sensitivity. A randomized clinical trial published in 2015 demonstrated that dentifrices containing 5% CSPS may have the potential to mineralize and occlude the dentine in the oral environment.

"Acoustic Weapons—A Prospective Assessment: Sources, Propagation, and Effects of Strong Sound" Experimentelle Physik III. Universität Dortmund, Dortmund, Germany It failed as a weapon, primarily because its range was not sufficient. Modern sonic weapons such the Long Range Acoustic Device (LRAD) rely on multiple loudspeaker drivers for increased sound power, and may array them in a flat plane rather than on a parabolic surface. Such weapons do not use parabolic reflectors which necessarily limit the number of drivers—a large area of drivers aimed at the reflector would occlude the parabolic dish.

The epithelium of the larynx is of endodermal origin, but the laryngeal cartilages, unlike the rest of the respiratory bud connective tissue, come from the mesenchyme of the fourth and sixth pharyngeal arches. The fourth pharyngeal arch, adjacent to what will be the root of the tongue, will become the epiglottis. The sixth pharyngeal arch, located around the laryngeal orifice, will become the thyroid, cricoid and arytenoid cartilages. These structures are formed in a process in which the lining cells of the primitive larynx proliferate and occlude it.

This structural transition can then expose or occlude important regions of RNA such as a ribosome binding site, which then affects the translation rate of a nearby protein-coding gene. RNA thermometers, along with riboswitches, are used as examples in support of the RNA world hypothesis. This theory proposes that RNA was once the sole nucleic acid present in cells, and was replaced by the current DNA → RNA → protein system. Examples of RNA thermometers include FourU, the Hsp90 cis- regulatory element, the ROSE element, the Lig RNA thermometer, and the Hsp17 thermometer.

The octahedron is difficult to set up in "upright" orientation, since the listener would occlude the floor speaker. Hence, a "slanted" setup is usually preferred. It provides basic full-sphere first-order reproduction for a single listener. Goodwin (2009) has suggested a slanted octahedron with separate front center (which he calls 3D7.1)Simon Goodwin, 3D sound for 3D games - beyond 5.1, AES 35th International Conference, London 2009 as an alternative way of using 7.1 systems to achieve with-height Ambisonic reproduction in games, and to allow reasonably accurate native 5.1 playback.

While multicuspid teeth are seen in many other notosuchians such as Simosuchus and Yacarerani, they are most complex in Pakasuchus. The molar-like teeth show a level of complexity that matches that of mammals, being able to occlude, or fit with one another, and provide sharp shearing edges for slicing food. Pakasuchus also differed from modern crocodilians, and many other crocodyliforms, in the reduction of osteoderms covering the body. Small, reduced osteoderms overlie the dorsal vertebrae, but fewer in number and are not as large as those of other notosuchians.

One of the drawbacks of vascular stents is the potential for restenosis via the development of a thick smooth muscle tissue inside the lumen, the so-called neointima. Development of a neointima is variable but can at times be so severe as to re-occlude the vessel lumen (restenosis), especially in the case of smaller-diameter vessels, which often results in reintervention. Consequently, current research focuses on the reduction of neointima after stent placement. Substantial improvements have been made, including the use of more biocompatible materials, anti-inflammatory drug- eluting stents, resorbable stents, and others.

The full-face mask must provide a means for the diver to block the nostrils for equalizing the middle ears. This may be provided in several ways. Some masks have a soft rubber nose pocket which allows the diver to pinch the nose directly, some have a soft cushion which can be pressed against the lower part of the nose to occlude the nostrils, and others have a mechanism which applies soft levers to the sides of the nose to pinch it in the same way that it would be done with fingers. The details of these mechanisms varies, but they all work.

In 1987, HBO purchased the rights to the series and dubbed it into English. Production for the English version was done by the Canada-based studio Cookie Jar Group (known then as Cinar). Actress Margot Kidder was hired as narrator, and the musical band Parachute Club provided songs for the series, which aired as a mini-series. This English version attempted to completely occlude the show's Japanese origins, going so far as to remove all Japanese names and studios from the credits and to credit key aspects of the animation to Westerners, which applied primarily to the CGI opening sequence.

Portal vein embolization (PVE) is a preoperative procedure performed in interventional radiology to initiate hypertrophy of the anticipated future liver remnant a couple weeks prior to a major liver resection procedure. The procedure involves injecting the right or left portal vein with embolic material to occlude portal blood flow. By occluding the blood flow to areas of the liver that will be resected away, the blood is diverted to healthy parts of the liver and induces hyperplasia. This may allow for a more extensive resection or stage bilateral resections that would otherwise be contraindicated resulting in better oncological treatment outcomes.

LDD accounts for 6-8% of all colics. # Right dorsal displacement: the colon moves between the cecum and body wall. # The pelvic flexure retroflexes towards the diaphragm # The colon develops a 180-degree volvulus, which may or may not occlude the vasculature of the organ. The cause of displacement is not definitively known, but one explanation is that the bowel becomes abnormally distended with gas (from excessive fermentation of grain, a change in the microbiota secondary to antibiotic use, or a buildup of gas secondary to impaction) which results in a shift in the bowel to an abnormal position.

From 1 to 4 percent of normal patients will test positive for Trousseau's sign of latent tetany. This sign may be positive before other manifestations of hypocalcemia such as hyperreflexia and tetany, as such it is generally believed to be more sensitive (94%) than the Chvostek sign (29%) for hypocalcemia.Schaat M, Payne CA. Effect of diphenylhydantoin and phenobarbital on latent tetany To elicit the sign, a blood pressure cuff is placed around the arm and inflated to a pressure greater than the systolic blood pressure and held in place for 3 minutes. This will occlude the brachial artery.

The DxO ONE works with iPads and iPhones running iOS 8 or later and that have a Lightning connector, and with some Android phones that have a USB-C connector. For proper connection between the mobile device and the DxO ONE, a case that does not occlude the area around the Lightning Connector is necessary. The DxO ONE can be used by itself, with its rear OLED screen allowing the user to switch between photo and video, but not to preview the image. For desktop processing of raw and SuperRAW images, an Apple Mac or Windows computer is required.

The early fire lance, considered to be the ancestor of firearms, is not considered a true gun because it did not include projectiles. Later on, shrapnel such as ceramics and bits of iron were added, but these didn't occlude the barrel, and were only swept along with the discharge rather than make use of windage. These projectiles were called "co-viatives." The commonplace nature of the fire lance, if not in quantity, was apparent by the mid 13th century, and in 1257 an arsenal in Jiankang Prefecture reported the manufacture of 333 "fire emitting tubes" (突火筒).

In 1259 a type of "fire-emitting lance" (tuhuoqiang 突火槍) made an appearance and according to the History of Song: "It is made from a large bamboo tube, and inside is stuffed a pellet wad (子窠). Once the fire goes off it completely spews the rear pellet wad forth, and the sound is like a bomb that can be heard for five hundred or more paces." The pellet wad mentioned is possibly the first true bullet in recorded history depending on how bullet is defined, as it did occlude the barrel, unlike previous co-viatives used in the fire lance.

The early fire lance, considered to be the ancestor of firearms, is not considered a true gun because it did not include projectiles. Later on, shrapnel such as ceramics and bits of iron were added, but these didn't occlude the barrel, and were only swept along with the discharge rather than make use of windage. These projectiles were called "co- viatives." The commonplace nature of the fire lance, if not in quantity, was apparent by the mid 13th century, and in 1257 an arsenal in Jiankang Prefecture reported the manufacture of 333 "fire emitting tubes" (突火筒).

In transcriptional silencing, SIR2,3,4 are required in stoichiometric amounts to silence genes in cis. In yeast, SIR proteins bind sites on nucleosome tails and form a multimeric compound of SIR2,3,4 that condenses chromatin and is thought to physically occlude promoters in the silenced interval, preventing their interaction with transcription machinery. The establishment of SIR-reppressed heterochromatin domains is a complicated process that involves different subsets of proteins and regulatory proteins depending on the locus in the genome. At the silent mating type loci and at yeast telomeres, the transcription factors Abf1 (ARS binding factor) and Rap1 (repressor-activator protein) associate with specific nucleotide sequences in the silencers that flank heterochromatic regions.

WHVP is used to estimate the portal venous pressure by reflecting not the actual hepatic portal vein pressure but the hepatic sinusoidal pressure. It is determined by wedging a catheter in a hepatic vein, to occlude it, and then measuring the pressure of proximal static blood (which is reflective of pressure in the sinusoids). WHVP in fact slightly underestimates portal pressure due to sinusoidal equilibration in patients without cirrhosis, but the difference between the two is clinically insignificant. In patients with cirrhotic livers intersinusoidal communication is disrupted such that sinusoidal pressure equilibrium cannot be maintained, and so WHVP becomes a far more accurate measure of portal venous pressure.

A carrier protein is required to move particles from areas of low concentration to areas of high concentration. These carrier proteins have receptors that bind to a specific molecule (substrate) needing transport. The molecule or ion to be transported (the substrate) must first bind at a binding site at the carrier molecule, with a certain binding affinity. Following binding, and while the binding site is facing the same way, the carrier will capture or occlude (take in and retain) the substrate within its molecular structure and cause an internal translocation so that the opening in the protein now faces the other side of the plasma membrane.

Magnetic vehicles started being used for drug delivery purposes of chemotherapeutic agents around 1960–1970. MTCs composition has varied over the years and differed between in-vitro and in-vivo studies. Dr. Widder synthesized albumin microspheres in the 1970s encasing Adriamycin, a chemotherapeutic drug, and used magnetite as the susceptible magnetic component to the external magnetic field. One of the first in vivo experiments using magnetic vehicles performed in humans was done by John F. Alksne and his associates in the 1960s, using carbon-coated iron and applied an external magnetic field in order to occlude intracranial aneurysms, which was considered a successful therapeutic once the X-ray results were analyzed.

Besides the molar relationship, the British Standards Institute Classification also classifies malocclusion into incisor relationship and canine relationship. Class I: The lower incisor edges occlude with or lie immediately below the cingulum plateau of the upper central incisors Class II: The lower incisor edges lie posterior to the cingulum plateau of the upper incisors Division 1 – the upper central incisors are proclined or of average inclination and there is an increase in overjet Division 2 – The upper central incisors are retroclined. The overjet is usually minimal or may be increased. Class III: The lower incisor edges lie anterior to the cingulum plateau of the upper incisors.

In 1961 Brian Arthur Sellick (1918–1996), an anaesthetist, published the paper Cricoid pressure to control regurgitation of stomach contents during induction of anesthesia—preliminary communication, describing the application of cricoid pressure for the prevention of regurgitation. The technique involves the application of backward pressure on the cricoid cartilage with a force of 20–44 newtons to occlude the esophagus, preventing aspiration of gastric contents during induction of anesthesia and in resuscitation of emergency victims when intubation is delayed or not possible. Some believe that cricoid pressure in pediatric population, especially neonates, improves glottic view and aids tracheal intubation apart from its classical role in rapid sequence intubation for aspiration prophylaxis.

The first week of November that year had been unusually mild with the jet stream much further north than usual. On the morning of the November 9 2005, a major autumn storm system was passing through northern Ontario (where heavy amounts of snow fell) with much milder air working in across the lower Great Lakes. As the system began to occlude, southern Ontario was forecast to be in the triple point, a favourable area for the development of severe thunderstorms due to high helicity values. Numerical models (especially the ETA model) had been predicting values of this, in excess of 600-800m^2/s^2 for the risk area.

Following declaration of death, cardiopulmonary resuscitation (CPR) is continued until the transplant team arrive. A stand-off period is observed after cessation of CPR to confirm that death has occurred; this is usually from 5 to 10 minutes in length and varies according to local protocols. Once the stand-off period has elapsed, a cut down is performed over the femoral artery, and a double-balloon triple- lumen (DBTL) catheter is inserted into the femoral artery and passed into the aorta. The balloons are inflated to occlude the aorta above and below the renal arteries (any donor blood specimens required can be taken before the top balloon is inflated).

Interventional oncology procedures are generally divided between diagnostic procedures that help obtain tissue diagnosis of suspicious neoplasms and therapeutic ones that aim to cure or palliate the tumour. Therapeutic interventional oncology procedures may be classified further into ablation techniques that destroy neoplastic tissues by delivery of some form of heat, cryo or electromagnetic energy and embolization techniques that aim to occlude the blood vessels feeding the tumour and thereby destroy it by means of ischemia. Both ablation and embolization techniques are minimally invasive treatment, i.e. they may be delivered through the skin (in a percutaneous way) without the need for any skin incisions or other form of open surgery.

The gas is then heated, generally to about 37 °C, and humidified to near 100% RH using a humidifier. The gas is transported to the patient through a heated delivery tube to prevent cooling and condensation of the water vapor that has been added to the respiratory gas(es). HFT requires the use of nasal cannulae and a system designed to deliver high flow rates and the pressure generated to do so. At the same time the nasal cannula must be small enough that they do not occlude more than 50% of the nares, as this allows flow to have multiple points of exit for a continuous airway flush effect.

House and his team treat a woman, Maggie, who suffers from sudden paralysis of her hands. House probes the patient and her daughter, trying to tease out a lie between them, but both insist that they are always honest with each other. As the team tries to cure the paralysis, Maggie loses her eyesight, and her other organ systems begin to shut down. The team believes Maggie's symptoms might be psychological in origin, but this is proven false when she is discovered to have severe calcification of her entire skeleton, and the lymph nodes in her neck begin to swell and occlude her airway.

Most of the cues required to provide humans with relative depth information are already present in traditional 2D films. For example, closer objects occlude further ones, distant objects are desaturated and hazy relative to near ones, and the brain subconsciously "knows" the distance of many objects when the height is known (e.g. a human figure subtending only a small amount of the screen is more likely to be 2 m tall and far away than 10 cm tall and close). In fact, only two of these depth cues are not already present in 2D films: stereopsis (or parallax) and the focus of the eyeball (accommodation).

The first three pairs of its maxillary teeth are large caniniform teeth, and in its lower jaw there are also three pairs of large caniniform teeth which are located immediately in front of the three maxillary caniniforms when the mouth is closed. Two pairs of the lower jaw caniniforms occlude between the last pair of premaxillary teeth and first pair of maxillary teeth in a diastema (gap in the tooth row). The enlargement of these two pairs of lower jaw teeth in K. queenslandicus may be related to the absence of a fifth pair of premaxillary teeth, which are present in a number of other pliosaurs. Oliver Hampe described Kronosaurus boyacensis as having five pairs of premaxillary teeth.

It may be possible to embolize vascular lesions through interventional radiology; this requires passing a catheter through a large artery and locating the maxillary artery under X-ray guidance, followed by the injection into the vessel of particles that occlude the blood vessels. The benefit from the procedure tends to be short-lived, and it may be most appropriate in episodes of severe bleeding. To more effectively minimize recurrence and severity of epistaxis, other options may be used in conjunction with therapies listed above. Intravenously administered anti-VEGF substances such as bevacizumab (brand name Avastin), pazopinab and thalidomide or its derivatives interfere with the production of new blood vessels that are weak and therefore prone to bleeding.

The mosaic tiles of this human figure in the Saint Stephen Church in Umm Er-Rasas in Jordan have been rearranged by aniconists. A black rectangular or square box (known as censor bars) may be simply be used to occlude parts of images completely (for example, a black bar covering the eyes instead of the entire face being pixelized). Censor bars were extensively used as a graphic device in the January 2012 protests against SOPA and PIPA. A drawback of pixelization is that any differences between the large pixels can be exploited in moving images to reconstruct the original, unpixelized image; squinting at a pixelized, moving image can sometimes achieve a similar result.

Grossly, LAM lungs are enlarged and diffusely cystic, with dilated air spaces as large as several centimeters in diameter. Microscopic examination of the lung reveals foci of smooth muscle-like cell infiltration of the lung parenchyma, airways, lymphatics, and blood vessels associated with areas of thin-walled cystic change. LAM lesions often contain an abundance of lymphatic channels, forming an anastomosing meshwork of slit-like spaces lined by endothelial cells. LAM cells generally expand interstitial spaces without violating tissue planes but have been observed to invade the airways, the pulmonary artery, the diaphragm, aorta, and retroperitoneal fat, to destroy bronchial cartilage and arteriolar walls, and to occlude the lumen of pulmonary arterioles.

The matching of the cusps allowed the teeth to occlude more precisely than in earlier cynodonts. It would grind its food between the teeth in somewhat the same way as a modern rodent, though unlike rodents tritylodontids had a palinal jaw stroke (front-to-back), instead of a propalinal one (back-to-front). The teeth were well suited for shredding plant matter; however, there is evidence that some tritylodontids had more omnivorous diets, much in the same vein as modern mammals with "herbivore dentitions" like modern rats. Like mammaliaformes, tritylodontids have epipubic bones, a possible synapomorphy between both clades, and this suggests they may also have laid eggs, or produced undeveloped fetus-like young like modern monotremes and marsupials.

The tensor veli palatini tenses the soft palate and by doing so, assists the levator veli palatini in elevating the palate to occlude and prevent entry of food into the nasopharynx during swallowing. The tensed palate consequently provides a stable platform for elevation of the pharynx during swallowing by the pharyngeal muscles. Since it is also attached to the lateral cartilaginous lamina of the auditory tube (also known as the Eustachian tube), it assists in its opening during swallowing or yawning to allow air pressure to equalize between the tympanic cavity and the outside air. Equalization of air pressure in the tympanic cavity is essential for preventing damage to the tympanic membrane and a resulting loss of hearing acuity.

Variants in IRF6 have yielded consistent evidence of association with syndromic cleft and/or palate across multiple studies. A study by Birnbaum and colleagues in 2009 confirmed the impact of this gene on the etiology of cleft lip and/or palate, and the GENEVA Cleft Consortium study, which studied families from multiple populations, reconfirmed the findings that IRF6 mutations are strongly associated with cleft and/or palate. A role of IRF6 in causing cleft lip and/or palate is further supported by analysis of IRF6 mutant mice which exhibit a hyper-proliferative epidermis that fails to undergo terminal differentiation, leading to multiple epithelial adhesions that can occlude the oral cavity and result in cleft palate.

The idea of creating interocclusal space was first proposed by DJ Andersen in 1962. He introduced the concept of experimental malocclusion by inducing the over-eruption of teeth, placing restorations in the dentition in supra-occlusion.Anderson, D.J. "Tooth movement in experimental malocclusion". Archives of Oral Biology. 7 (1): 7–15. doi:10.1016/0003-9969(62)90043-2. Anderson carried out a study on five human adult subjects aged 19–49 years; by placing a 0.5mm metal bite-raising cap on the occlusal surface of the subjects’ lower right first permanent molars, he found that each of the subjects were able to occlude their teeth after an experimental period of 23–41 days.

The wound is now ready to be stitched or for thorns > to be applied. If a needle and thread are being used, close tight sutures > will be placed to ensure that a flap of skin covers the vulva and extends > from the mons veneris to the perineum, and which, after the wound heals, > will form a bridge of scar tissue that will totally occlude the vaginal > introitus.. The amputated parts might be placed in a pouch for the girl to wear. A single hole of 2–3 mm is left for the passage of urine and menstrual fluid. The vulva is closed with surgical thread, or agave or acacia thorns, and might be covered with a poultice of raw egg, herbs and sugar.

Buckhorn sights have extensions protruding from either side of the rear sight forming a large ring which almost meets directly above the "V" of the notch. The semi-buckhorn is similar but has a wider gently curving notch with the more precise "V" at its center and is standard on classic Winchester and Marlin lever-action rifles. Express sights are most often used on heavy caliber rifles intended for the hunting of dangerous big game, and are in the form of a wide and large "V" with a heavy white contrast line marking its bottom and a big white or gold bead front sight. These sights do not occlude the target as much as some other styles which is useful in the case of a charging animal.

A large bubble of air in the heart (as can follow certain traumas in which air freely gains access to large veins) will present with a constant "machinery" murmur. It is important to promptly place the patient in Trendelenburg position (head down) and on their left side (left lateral decubitus position). The Trendelendburg position keeps a left-ventricular air bubble away from the coronary artery ostia (which are near the aortic valve) so that air bubbles do not enter and occlude the coronary arteries (which would cause a heart attack). Left lateral decubitus positioning helps to trap air in the non-dependent segment of the right ventricle (where it is more likely to remain instead of progressing into the pulmonary artery and occluding it).

Reversible inhibition of sperm under guidance (RISUG) is a non-toxic polymer gel-based contraceptive that is injected into the lumen of the vas deferens and results in infertility within 10 days following injection. RISUG is composed of styrene maleic anhydride (SMA) dissolved in dimethyl sulfoxide (dimethyl sulfoxide), which is believed to both partially occlude the vas deferens by coating the inner walls of the vas deferens with the polymer chemical, while also deactivating the sperm that are able to pass through the partially occluded vas deferens, thereby preventing successful fertilization. The exact mechanism of the deactivation effect on sperm is still unknown. RISUG inhibits sperm transport but allows fluid to pass through, which prevents pressure from building up in the vas deferens.

The west and east elevations were predominantly windowless to occlude the harsh, low sun and were built of concrete to provide a thermal mass quality. In contrast, the photographic and computational spaces that required highly controlled light and ventilation conditions were located in the basement levels, which had deep floor plans and limited fenestration. An upturn in the city's economy and a modernising of the building codes that included a removal of building height limits in 1964 saw a considerable increase in the construction of highrise office buildings in Brisbane. Between 1950 and 1965 few office highrise buildings were constructed in Brisbane. These included: Mutual Life & Citizens (MLC) Insurance Building (1955); Friendly Society Building (1957), and the Taxation Building (1961).

In 1259 a type of "fire-emitting lance" (突火槍) made an appearance and according to the History of Song: "It is made from a large bamboo tube, and inside is stuffed a pellet wad (子窠). Once the fire goes off it completely spews the rear pellet wad forth, and the sound is like a bomb that can be heard for five hundred or more paces." The pellet wad mentioned is possibly the first true bullet in recorded history depending on how bullet is defined, as it did occlude the barrel, unlike previous co-viatives used in the fire lance. Fire lances transformed from the "bamboo- (or wood- or paper-) barreled firearm to the metal-barreled firearm" to better withstand the explosive pressure of gunpowder.

On November 3, 2013, Kubiak collapsed as he was walking off the field at halftime of the game against the Indianapolis Colts. He was put on a backboard and stretcher and transported to the hospital as a precautionary measure. Initial reports stated that he had not had a heart attack. An NFL report on Monday, November 4, 2013, indicated that he had suffered a transient ischemic attack (TIA), or relatively brief, non-permanent symptoms of disorientation, confusion, dizziness, forgetfulness, and/or vertigo (among many other possibilities), that occurs when a blood vessel or vessels in part(s) of the brain are temporarily but not permanently blocked, usually by a stationary clot (a thrombus) or one that has broken off and traveled to occlude another area (an embolus).

Anomocephaloidea is a clade (evolutionary grouping) of anomodont therapsids that existed in Gondwana during the Middle Permian and includes two species, Anomocephalus africanus from South Africa and Tiarajudens eccentricus from Brazil, both of which are characterized by large body size and teeth that fit tightly together or occlude. Anomocephaloidea is among the most basal groups of anomodonts, the other being Venyukovioidea, which differs in being a Laurasian clade of mostly small-bodied species. Anomocephaloidea was named in 2011 with the discovery of Tiarajudens; Anomocephalus had been known since 1999, but was unique among anomodonts until Tiarajudens was described. Both Anomocephalus and Tiarajudens were herbivores, although the latter possessed a pair of saber-like canine teeth that may have been used in display or combat with other individuals of the same species.

The cannon may have possibly appeared in China as early as the 12th century, but did not see wider use in the region until the 13th century. The cannon was likely a parallel development or evolution of the fire-lance, a 12th-century gunpowder weapon that combined a tube of gunpowder with a polearm weapon. This early fire lance is not considered a true gun because it did not include projectiles, whereas a gun by definition uses "the explosive force of the gunpowder to propel a projectile from a tube: cannons, muskets, and pistols are typical examples." However co-viative projectiles, which only partially occlude the barrel, such as iron scraps or porcelain shards were added at some point, and eventually, the paper and bamboo materials of fire lance barrels were replaced by metal.

In 2006, Jonathan Whitlock and colleagues reported on a series of experiments that provided perhaps the strongest evidence of LTP's role in behavioral memory, arguing that to conclude that LTP underlies behavioral learning, the two processes must both mimic and occlude one another. Employing an inhibitory avoidance learning paradigm, researchers trained rats in a two- chambered apparatus with light and dark chambers, the latter being fitted with a device that delivered a foot shock to the rat upon entry. An analysis of CA1 hippocampal synapses revealed that inhibitory avoidance training induced in vivo AMPA receptor phosphorylation of the same type as that seen in LTP in vitro; that is, inhibitory avoidance training mimicked LTP. In addition, synapses potentiated during training could not be further potentiated by experimental manipulations that would have otherwise induced LTP; that is, inhibitory avoidance training occluded LTP.

Their almost concurrently invented devices consisted of a narrow armlet to occlude the brachial artery, a small bicycle-type metal pump and a metal manometer graduated in mmHg.Hill L, Barnard H: A simple and accurate form of sphygmometer or arterial pressure gauge contrived for clinical use. BMJ 1897 ii 904 It seems surprising that the first report of blood pressure monitoring during anesthesia did not mention the use of sphygmographs, which had already been in common use at this time . One reason might be that the former practice totally relied on the observation of breathing as the sole method of monitoring; even the palpation of pulse during ether or chloroform administration was not recognized as a good practice. Another reason may be found directly in the title of the report: “A simple and accurate form of sphygmometer or arterial pressure gauge contrived for clinical use” – implying that for clinical use the device must be simple and accurate.

Some problems which may or may not occur with third molars: A Mesio-impacted, partially erupted mandibular third molar, B Dental caries and periodontal defects associated with both the third and second molars, caused by food packing and poor access to oral hygiene methods, C Inflamed operculum covering partially erupted lower third molar, with accumulation of food debris and bacteria underneath, D The upper third molar has over-erupted due to lack of opposing tooth contact, and may start to traumatically occlude into the operculum over the lower third molar. Unopposed teeth are usually sharp because they have not been blunted by another tooth. Dental x-ray of impacted lower right wisdom tooth with a horizontal orientation Impacted wisdom teeth are classified by the direction and depth of impaction, the amount of available space for tooth eruption and the amount soft tissue or bone that covers them. The classification structure allows clinicians to estimate the probabilities of impaction, infections and complications associated with wisdom teeth removal.

In 1259 a type of "fire-emitting lance" (突火槍) made an appearance and according to the History of Song: "It is made from a large bamboo tube, and inside is stuffed a pellet wad (子窠). Once the fire goes off it completely spews the rear pellet wad forth, and the sound is like a bomb that can be heard for five hundred or more paces." The pellet wad mentioned is possibly the first true bullet in recorded history depending on how bullet is defined, as it did occlude the barrel, unlike previous co-viatives used in the fire lance. Fire lances transformed from the "bamboo- (or wood- or paper-) barreled firearm to the metal-barreled firearm" to better withstand the explosive pressure of gunpowder. From there it branched off into several different gunpowder weapons known as "eruptors" in the late 12th and early 13th centuries, with different functions such as the "filling-the-sky erupting tube" which spewed out poisonous gas and porcelain shards, the "orifice-penetrating flying sand magic mist tube" (鑽穴飛砂神霧筒) which spewed forth sand and poisonous chemicals into orifices, and the more conventional "phalanx-charging fire gourd" which shot out lead pellets.