Metastasis/Pithoprakta/Eonta isn't electronic but it has "Metastasis," which is probably his best known composition.
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Investigating metastasis seems more straightforward than investigating non-metastasis; clinically speaking, it's tough to study those who haven't fallen ill.
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Now I think more and more of a different question: Why was my father's body more receptive to prostate metastasis versus melanoma metastasis?
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In still others, the lungs had visibly blackened with metastasis.
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"[Metastasis] happens to a big extent of the patients," he says.
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Paget's study concentrated on patterns of metastasis within a person's body.
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"It was rejected because the relevance [to metastasis] wasn't clear," he said.
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Metastasis is the leading cause (90 percent) of all cancer-related deaths.
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The primary melanoma was surgically resected, and no metastasis was ever found.
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However, the mandate given to Mueller is a virtual pathway for metastasis.
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His last diagnosis was another metastasis, grown on one of his vertebrae.
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Was there any way to know whether she was likely to suffer metastasis?
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Enormous, empty, uncolonized steppes—anatomical landmasses untouched by metastasis—stretched out in between.
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"It's possible we didn't get a high enough dose of the nanoparticles in all of the mice, because it limited metastasis even in the ones that still got metastasis—so it wasn't as if there was no effect," Egeblad said.
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Benign and metastasis were the least understood terms, with 33 percent of patients responding "Don't know" for the meaning of benign and just 6 percent correctly defining metastasis as the spread of a cancer to other areas of the body.
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This meeting was full of metastasis biologists looking at cancer cells under the microscope.
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Evidence suggested, for example, that most men with prostate cancer would never experience metastasis.
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Massagué's team had implicated these cells as crucial surveyors and controllers of cancer metastasis.
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They hope to find clues to metastasis, the way cancer spreads through the body.
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But this cultural metastasis has led to a swift and less-than-discriminate backlash.
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Increasingly sophisticated imaging techniques are allowing doctors to spot previously undetectable signs of metastasis.
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Can you picture the process of metastasis, the spread of cancerous cells through the body?
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Adams's particular interest was in host genes, rather than cell types, that might affect metastasis.
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In the past few years, physicists studying metastasis have generated surprisingly precise predictions of cell behavior.
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One day in March, 2012, Welch flew to Washington to attend a conference on cancer metastasis.
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When my lung metastasis progressed last year, I was glad Ma wasn't around to see it.
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When my lung metastasis progressed last year, I was glad Ma wasn't around to see it.
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Using publicly available data they attempted to map how cancer spreads through the body, known as metastasis.
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Ms Milley experienced this when she had a superficial brain metastasis dealt with by stereotactic radio-surgery.
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Bones were a frequent site of metastasis in breast cancer—but not every bone was equally susceptible.
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Caitlyn M. Dlouhy, his editor at Simon & Schuster, said the cause was multiple myeloma with bone metastasis.
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Then in 2017, Philipp was diagnosed with a metastasis and had to go through strong chemotherapy treatments.
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The lymph nodes in the armpits—a frequent site of cancer metastasis—also contained no sign of cancer.
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Are the prostate tumors in men who became fat by eating high-sugar diets equally susceptible to metastasis?
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Follow the #StageIVStampede on Twitter, and call your reps to demand they ask for more funding for metastasis research.
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It is a "metastasis of the PP", from which some of its leaders come, says a former Socialist leader.
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Oncologists had spent generations studying one possible outcome of that battle: when the woman lost, she succumbed to metastasis.
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I discovered the bone metastasis a few months later, and my doctors decided there was no treatment benefit to surgery.
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The metastasis of this model today may be an even greater threat to the nation's political health than Trump himself.
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Casting players in the role of a disembodied, almost godlike ruler, Stellaris struggles to comprehend fascism's populist nature and metastasis.
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"I believe that fake news is the cancer of our times and social media the vehicles for metastasis," he wrote.
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Was this resistance to metastasis peculiar to melanoma, which is a type of cancer well known to provoke an immune response?
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In the Bay Area, the metastasis of the Not In My Backyard—or "NIMBY"—ideology prevented or restricted new housing construction.
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Among the three groups there was no difference in cancer recurrence, metastasis to distant parts of the body or death rates.
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In the enzalutamide study, metastasis took 36.6 months on average in men receiving that drug compared to 14.7 months with placebo.
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What's new is the existence — and metastasis — of the fury factories of the right, from Fox News to Breitbart to Frontpage Mag.
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"She does not display hyperpigmentation from radiation or scars claimed from the multiple surgeries due to admitted liver and lung metastasis," Maclin wrote.
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Cancer spreads throughout the body—a process known as metastasis—when certain cells break off from the primary tumor and enter the bloodstream.
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Why was the liver so hospitable to metastasis, while the spleen, which had similarities in blood supply, size, and proximity, seemed relatively resistant?
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Occasionally, mutations were detected in cancer metastases that were different from the primary tumor, but no mutations emerged as singular drivers of metastasis.
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Many patients also seemed to mistake "metastasis" for other words, offering responses such as "foot bone" (metatarsal) or "breast condition, very painful" (mastitis).
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It's the one thing bureaucracies do well: perpetuate themselves through organizational metastasis, whereby every good idea—or every change agent with one—is eliminated.
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It was the well-funded metastasis of extreme Saudi religious intolerance — its Wahhabi orthodoxy — into forms of murderous Islamist hatred of the apostate West.
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The scientists also investigated the effects of anti-cancer drugs in cancer metastasis, providing a unique glimpse of how medicine works inside a live organism.
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The "different cancers into same strain" experiments have allowed cancer biologists to observe how alterations in cancer genes might affect their growth, metabolism, and metastasis.
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Whoever wins, and however fair the victory may be, I remain skeptical: The right-wing project coalesced long ago, and its metastasis has been rapid.
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The women in the SCALP trial will be followed for five years to monitor overall survival, recurrence of cancer and potential metastasis to the scalp.
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The tumor has a low chance of metastasis but needs to monitored for the remainder of her life in the event of regrowth, the shelter said.
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In the late eighties, a number of cancer biologists, Weinberg most prominently among them, threw themselves into finding such genes for metastasis—met genes, in effect.
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Two years later, van der Weyden had inoculated eight hundred and ten mouse strains with the melanoma cells and scrutinized the physiology of metastasis in each.
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In 2001, Joan Massagué, a cancer biologist at New York's Memorial Sloan Kettering Cancer Center, came upon a scientific paper that radically changed his thinking about metastasis.
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Obama cannot understand that millions of American women actually care about right-sizing the tax-and-spend entitlement state that experienced unprecedented metastasis under her husband's administration.
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"It's likely that these transmission events that we're looking at in the mollusks could be comparable to the metastasis of cancer within a single person," Goff explained.
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In 1984, Brinker herself was diagnosed with breast cancer and although successfully treated has lived with various side-effect related health issues, and the fear of metastasis.
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In a free-written answer section, they were also asked to describe in their own words the meanings of: biopsy, tumor, lymph node, pre-malignant and metastasis.
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He underwent six weeks of raditation before he enrolled in the SurVaxM trial, which is being conducted at the Brain Metastasis Research Program at Cleveland Clinic's Neurological Institute.
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They theorized that these structures, which they called an "unrecognized interstitium," were likely to play a key role in cancer metastasis, the process by which tumor cells spread.
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"This information changes the standard narrative of how metastasis [begins] and allows us to devise better ways to combat it," lead author Sam Au said in a statement.
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Paget's way of framing the issue—metastasis as the result of a pathological relationship between a cancer cell and its environment—lay dormant for more than a century.
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The pioneering metastasis researcher Isaiah J. Fidler, working at the National Cancer Institute during the nineteen-seventies and eighties, started to study "cross-talk" between tissue and tumor.
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Most of those who've received a transplant with unresectable metastasis in the liver from colorectal cancer, Cleveland's Dr. Aucejo said, experience a recurrence of cancer within 12 months.
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When I was diagnosed with stage 4 — and a very bad stage 4, with both visceral and bone metastasis — less than 18 months later, now THAT was life altering.
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Metastasis occurs when cancer cells break away from a primary cancer and travel through the blood or lymph system in other parts of the body to form new cancers.
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The speaker was still Ted Cruz, who did not happily welcome the crowd's hate so much as grow stronger and more terrifying because of it, a malignant metastasis in action.
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Metastasis can seem "like a random act of violence," Daniel Hayes, a breast oncologist at the University of Michigan, told me when we spoke at the asco meeting in Chicago.
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Herbert Levine, a biophysicist at Rice University, and his late colleague Eshel Ben-Jacob of Tel Aviv University recently created a model of metastasis based on concepts borrowed from nonlinear dynamics.
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" It goes on to say: "consequently, leeches have made a comeback as a new remedy for many chronic and life-threatening abnormalities, such as cardiovascular problems, cancer, metastasis, and infectious diseases.
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And while the five-year survival rate for women with early-stage breast cancer is 99% (a number worth celebrating), for those with metastasis, that number drops down to just 26%.
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At the new lab he runs at the University of California, San Francisco, he and his team try to understand the disease's molecular processes, building on his research into disease metastasis.
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"A visible, clinical metastasis—the kind that we can detect with CAT scans or MRIs—must only occur once a dormant cell has been reactivated and begins to divide," he said.
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" He explained that in the late 1980s and 1990s, surgeons tried transplants on patients like Erika with "unresectable metastasis in the liver from colorectal cancer," but the "outcomes were not good.
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These are cells that have broken off a primary tumour and which, if left unchecked, might lodge in various parts of the body and turn into secondary cancers, a process called metastasis.
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Stage IV breast cancer is responsible for virtually all breast cancer deaths, yet only between an estimated 2% and 7% of the funds raised for breast cancer research go toward investigating metastasis.
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Pearl is currently getting chemotherapy (Adriamycin, $173.25) with a healthy side of line items (IV catheter $100.43; chemotherapy administration, $48.50) every three weeks to decrease the chance of, or at least delay, metastasis.
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But if primary human tumors shed cells continually, and if every cell is capable of forming visible metastasis, then every patient should have countless visible metastatic deposits all over his or her body.
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The mysteries of metastasis, the intractability of anxiety disorders and strange new diseases of blood cells kept our brains and souls alive when the hospital was asking us to punch numbers into terminals.
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Radiation treatment and treatment with a number of anti-cancer drugs at the cancer center where I work has failed to stop the growth or metastasis of this tumor for more than a few months.
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The rule represents a metastasis from the Supreme Court's Hobby Lobby decision in 2014, which granted an exemption on the understanding that female employees would get their birth-control coverage directly from the employer's insurance carrier.
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Justice Gilmar Mendes said in an interview with Reuters that the so-called Car Wash investigation was a success in battling the "metastasis of corruption" in Brazil but it became politicized and prosecutors went too far.
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BERLIN, Dec 1 (Reuters) - Bayer is sticking to its peak sales estimate for bone metastasis drug Xofigo despite a setback in a late-stage drug trial, the head of the German group's pharmaceuticals unit said on Friday.
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In Cleveland, Dr. Aucejo is trailblazing the field for patients like Erika, having performed the only two transplants in America this century on people suffering from what is called unresectable metastasis in the liver from colorectal cancer.
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The drug, Xtandi, in combination with an anti-hormone therapy showed statistically significant improvement in metastasis-free survival rate in men with non-metastatic castration-resistant prostate cancer (CRPC) when compared with the standalone anti-hormone therapy.
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"If this variant does play a role in cancer metastasis, it would be an example where a genetic variant which rises to high frequency due to protection from malaria may also be associated with disease risk", she adds.
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According to Metavivor, a patient-run MBC organization, the percentage is even lower — just 2 to 5% — if you exclude research on the prevention and progression of metastasis and focus only on treating the patient with already metastasized disease.
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According to Metavivor, a patient-run MBC organization, the percentage is even lower — just 2 to 3% — if you exclude research on the prevention and progression of metastasis and focus only on treating the patient with already metastasized disease.
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A tumor, Fidler showed, is made of a heterogeneous mixture of millions of cells, only a fraction of which are equipped to leave the primary tumor, form an exploitative alliance with the "soil" of another organ, and initiate metastasis.
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It is a cautionary tale for any White House: The real danger of a scandal is not the discovery of the primary cancer but the risk of metastasis, or spreading of a cancer to all parts of a body.
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In particular, they wanted to see if combining two types of cancer therapies was effective at stopping the spread of cancer—known as metastasis—after the surgical removal of a tumor, which can promote the spread of the cancer.
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Oncologists have suspected for several decades that metastasis usually requires a transition between sticky epithelial cells, which make up the bulk of solid tumors, and thinner, more mobile mesenchymal cells that are often found circulating solo in cancer patients' bloodstreams.
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Post vaccination results included: a lower-than-expected level of tumor recurrence, a significantly lower rate of metastasis, and showed that the addition of other immunotherapy treatments (like anti-PD-1) is usually very effective for those cases where there was tumor growth.
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Notably, the strain carries a variant in a gene called Spns2, which, through a cascade of events, increases the concentration of immune cells, notably NK cells, in the lungs—the very cells that Massagué's lab had identified as a powerful restrictor of metastasis.
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Valerie Garguilo, 54, of Bellport, N.Y., watched her sister die in 2008 after a seven-year bout with breast cancer that was treated with a lumpectomy followed by two recurrences and two more lumpectomies, and then metastasis to her bones and brain.
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A primary tumor is shedding cells that move to a new location, a new organ within that same person, so there's an enormous effort to try to understand that and to try to understand the mutations that allow for metastasis in human cancers.
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The oncologist and director of translational genetics at the Johns Hopkins Kimmel Cancer Center has spent decades uncovering the unique sets of mutations that define cancers—the kind of genetic signals that not only drive tumor formation and metastasis, but distinguish one cancer from another.
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The data from a highly anticipated study released on Monday showed that it took 36.6 months for the disease to spread to other parts of the body in patients who received Xtandi plus androgen deprivation therapy (ADT), a measure known as median metastasis-free survival.
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The study, intended to bring the drug to bone metastasis patients at an earlier stage of treatment, was then unblinded in the interest of patient safety, meaning participants and doctors were told who received Xofigo and who was part of the control group on ineffective placebo.
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The ability to identify cancer in its early stages is particularly important given that survival rates for women with Stage 22019 or Stage 1 breast cancer are close to 100 percent, but decline to 72 percent by Stage 3, and to 22 percent after metastasis has occurred.
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A 'quest for finding better treatments' Clinical trials being conducted across the United States are exploring immunotherapies, vaccines and targeted therapies in addition to traditional treatments, said Dr. Manmeet Ahluwalia, a brain tumor oncologist, professor and director of the brain metastasis program at the Cleveland Clinic in Ohio.
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In a survey of London oral and maxillofacial surgery clinic patients, more than a third of participants did not know the meaning of terms like "benign" or "lesion" and more than half could not define "metastasis" or "lymph node," the study team reports in the British Dental Journal.
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That leaves many governments invested in vague hopes that such a settlement, however rickety or superficial, will somehow stop the metastasis of the Syrian crisis and ease fears of Islamic State terrorism — often conflated with concerns about ordinary Syrian refugees — that have fueled the rise of right-wing politicians.
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These included ATR, which detects damage to DNA and halts the cycle of cell division that cancer-promoting mutations encourage; AMER1, which stifles cell growth; and RECK, which reins in metastasis, the tendency of cancer cells to peel off their natal tumour and wander around the body looking for other sites to colonise.
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"I met my first patient with breast cancer when I was 21, in the 22s, and for me it was really striking how many young women were in the hospital dying of metastatic breast cancer," says Matthew Ellis, MD, PhD, a breast cancer physician and metastasis researcher at Baylor College of Medicine in Houston.
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To see if the nanoparticles had any effect on cancer metastasis—the process by which cancer spreads from tissue to tissue and from organ to organ—they treated mice with small-cell lung cancer in the hope that this would have an effect on the cancer's spread to the liver, a common metastatic outcome.
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"Cancer cells that have moved from breast tissue to other organs have not only survived all the different poisons used to treat the original tumor, but have had to adapt and make so many changes to be able to survive in a completely new tissue environment," says researcher Barbara Fingleton, PhD, who studies metastasis at the Vanderbilt-Ingram Cancer Center in Nashville.
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But a surprising amount of weight was seemingly put on the fact that scans were made of his spine and that a catheter had been used in his spinal cord — features that I and my colleagues might not have recognized as predictors of dying (an MRI of the spinal cord, I later realized, was most likely signaling cancer in the nervous system — a deadly site for metastasis).
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