131 Sentences With "localise" | Random Sentence Generator

With Barbie, Mattel tried to localise in the wrong way.

He said officials were attempting to localise the infected server to prevent the malware from spreading.

He previously worked at the local divisions of Yahoo and TripAdvisor, two American internet firms which struggled to localise.

Saudi Arabian Military Industries, owned by the kingdom's sovereign wealth fund, is spearheading the drive to localise military spending.

He also added that electric vehicles were gaining market share and PIF wanted to localise the industry in Saudi Arabia.

Tesla has previously said it wants to localise its entire supply chain in China by the end of this year.

The venture is also planning to revamp some of its existing manufacturing facilities to localise production of Ford's premium brand Lincoln.

Two years later, McDonald's had a reported 320 million customers per year in India, thanks to its efforts to localise its menu.

It has also said it would localise management teams by hiring more Chinese staff and aimed to improve relationships with joint venture partners.

TVS, the third-largest maker of two-wheelers in India, is also exploring suppliers in other regions and is looking to localise its supplies within India, it added.

The Silicon Valley giants already localise their services in dozens of languages; neural networks and other software allow new versions to be generated faster and more efficiently than ever.

"Anything that we try to do we will try to localise and assemble them," he said, adding that this could include construction equipment and heavy-duty power generator systems.

Even before the recent tensions, Riyadh had begun a drive to localise 50% of military spending led by Saudi Arabian Military Industries, owned by the state Public Investment Fund (PIF).

His troubles reveal the dynamics that many left-leaning college campuses are struggling with as activists, eager to localise national issues of racial and economic justice, find soft targets and dub them pariahs.

"Efforts to localise the infected server are underway to prevent (the ransomware) from spreading," he said, adding that his ministry was working with other authorities, including the Health Ministry, to solve the problem.

The company, established in May 2017, seeks to localise 50 percent of military spending by 2030 as part of Crown Prince Mohammed bin Salman's plan to diversify the kingdom's economy away from oil revenue.

Audi separately said it aims to double its China production with local partner FAW within five years, the firm's chief executive said on Wednesday, as global carmakers look to localise in the world's largest vehicle market.

"On top of local suppliers' efforts, current nationwide efforts to localise high-tech materials will continue, but we cannot replace all materials by ourselves," said an executive at a South Korean supplier for Samsung and SK Hynix.

SHANGHAI, Aug 2 (Reuters) - Tencent and Nintendo said on Friday they were working together to localise the Japanese gaming firm's classic Switch games for the Chinese market and set up a server through the Chinese company's cloud service.

SHANGHAI, April 25 (Reuters) - German luxury carmaker Audi AG aims to double its China production with local partner FAW within five years, the firm's chief executive said on Wednesday, as global carmakers look to localise in the world's largest vehicle market.

ABU DHABI, Feb 18 (Reuters) - State-owned Saudi Arabian Military Industries (SAMI) aims to generate $10 billion in revenue over the next five years, its chief executive said on Monday, as the wealth fund-backed group spearheads a drive to localise military spending.

"It uses computer vision technology to localise the user within the store and from there it uses integrated store layouts and up-to-date stock information to show product details and other relevant data to guide a customer around any store," said Hart.

"We will take a final decision in the coming weeks about which model to localise next in China," Peter said, adding that sales of the X3 offroader have risen since BMW decided to build it in Asia, cutting its reliance on exports from the United States.

As part of measures designed to create 1.6 million manufacturing and logistics jobs by 2030, Prince Mohammed wants to localise half the production of imported vehicles and weapons - which are expected to account for up to $100 billion in spending by Saudi government entities and consumers by 2030.

There, it has been a key partner to retailers and brands interested in expanding into the region, providing integrations to localise storefronts, a platform to help brands manage customer and marketplace relations, and analytics, competing against the likes of SAP, Oracle, Adobe and Salesforce (but not, he said in answer to my question, Commercetools, which builds Shopify -style API tools for mid and large-sized enterprises and itself raised $145 million last month).

It is thought that these channels may form heterodimers where their expressions co-localise.

Purlytin has been reported to localise in skin and produce a photoreaction 7–14 days post-administration.

As of August 2013, Capcom announced they have no plans to localise the title for other regions.

The first issue they tackled in 2012-2013 was to localise their procurement spend in Preston and the surrounding county of Lancashire.

In the brain, Rab18 has been isolated in association with synaptic vesicles and has been observed to localise to secretory granules in neuroendocrine cells.

Following the project goal to localise design and production, 92% of the parts and 87% of the added value came from domestic manufacturers or researchers.

FSMK is driving a software project "Rasi", a social networking portal to contribute in localization projects. This project was named after the late Free Software Activist Rasinesh. Project is launched in GitHub. Efforts are on to localise GNU Health to Kannada.

Dockerins are commonly found in proteins that localise to the fungal cellulosome, a large extracellular multiprotein complex that breaks down cellulose. It is therefore suggested that celpin may protect the cellulosome against plant proteases. Certain bacterial serpins similarly localize to the cellulosome.

GBP2 gene is located in a various compartment in the cell: nucleus, cytosol and cytoskeleton and also the dimer GBP2-GBP5 localise to the Golgi apparatus. In addition, the Isoprenylation is required to regulate the intracellular localization and the membrane association of GBP2.

Chondrolectin is a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein has been shown to localise to the perinucleus.

The exact function of chondrolectin is unknown but it has been show to be a marker of fast motor neurons in mice, and is involved in motor neuron development and growth in zebrafish (danio rerio). Furthermore, human chondrolectin has been shown to localise to motor neurons within the spinal cord.

MTV France is a French pay-television channel operated by ViacomCBS Networks EMEAA. It was launched as MTV Networks Europe began to further localise its brand throughout Europe. MTV France (previously MTVF) was launched on 20 June 2000. It is also distributed in Belgium (Wallonia), Switzerland (Romandie), Monaco and Francophone Africa.

It is also being used increasingly during surgery for brain tumors. Diluted fluorescein dye has been used to localise multiple muscular ventricular septal defects during open heart surgery and confirm the presence of any residual defects. The Gemini 4 spacecraft releases dye into the water, to aid location after splashdown, June 1965.

Apart from finding its attributes and relation to the other objects, localisation is also an important step. Thus, as a next step the query generator tries to localise the object in the region it was first identified, so it restricts the set of instantiation questions to the regions within the original region.

In 2010, WelTec partnered with the Thorndon Trust to resurrect the residency. Support is also provided by Creative New Zealand. The current residency guidelines require artists to submit proposals for a project they would like to complete while living at the cottage, with a brief to "localise the concepts 'technology' and 'culture' in the context of Aotearoa/New Zealand".

Altering the peripheral functionality of porphyrin-type chromophores can affect photodynamic activity. Diamino platinum porphyrins show high anti-tumour activity, demonstrating the combined effect of the cytotoxicity of the platinum complex and the photodynamic activity of the porphyrin species. Positively charged PC derivatives have been investigated. Cationic species are believed to selectively localise in the mitochondria.

A staunch defender of this view is William Uttal, who argues in The New Phrenology (2003) that there are serious philosophical, theoretical, and methodological problems with the entire enterprise of trying to localise cognitive processes in the brain.Uttal, William R. (2003). The New Phrenology: The Limits of Localizing Cognitive Processes in the Brain. Cambridge, Massachusetts: MIT Press.

Scintigraphy of the lungs may detect moderate to severe alterations in the perfusion and possibly ventilation of the dorso-caudal lung. The use of radio-labelled red blood cells and scintigraphy to localise and or quantify hemorrhage is not useful due to general sequestration of labeled RBC by the lung, even in the absence of hemorrhage.

The first South African live techno bands were the Kraftreaktor and The Kiwi Experience. Jay Sonton and Ruediger Keller from Kraftreaktor and the Kiwi Experience performed at several raves, playing mainly electronic body music. Their music was mainly influenced by European artists, but included a unique South African touch. They mainly integrated African samples to localise their sound.

The Duplex theory proposed by Lord Rayleigh (1907) provides an explanation for the ability of humans to localise sounds by time differences between the sounds reaching each ear (ITDs) and differences in sound level entering the ears (interaural level differences, ILDs). But there still lies a question whether ITD or ILD is prominent. The duplex theory states that ITDs are used to localise low frequency sounds, in particular, while ILDs are used in the localisation of high frequency sound inputs. However, the frequency ranges for which the auditory system can use ITDs and ILDs significantly overlap, and most natural sounds will have both high and low frequency components, so that the auditory system will in most cases have to combine information from both ITDs and ILDs to judge the location of a sound source.

Solca was one of the oldest villages in Cieszyn Silesia. A document of Bishop of Wrocław issued on 23 May 1223 for Norbertine Sisters in Rybnik includes a following excerpt:I. Panic, 2010, p. 387 Except for Sale all the mentioned villages were lying in the vicinity of Rybnik, thus it is problematic to localise where the settlement was supposed to be.

Proxecto Trasno logotype The Proxecto Trasno is an open community dedicated to localise open-source software to Galician language.Open source observatory, Gijs Hillenius: "Galician NGO challenges gvt support for proprietary software", 2013.Praza: "O futuro escríbese co T de tecnoloxía, é necesario que o idioma estea presente nela". 2014. "O Trasno loita polo Linux en galego" Vieiros: A Xunta reúnese co Trasno. 2006.

An emerging phase may be to simulate brain activity. In culture, the philosophy of mind has for centuries attempted to address the question of the nature of consciousness and the mind-body problem. The pseudoscience of phrenology attempted to localise personality attributes to regions of the cortex in the 19th century. In science fiction, brain transplants are imagined in tales such as the 1942 Donovan's Brain.

He explained the difference between the two models to the House of Commons Health Select Committee on 19 July 2008. A key principle of A Framework for Action is to "localise where possible, centralise where necessary." This would move "routine healthcare" away from acute hospitals and into community-based centres to provide a one-stop-shop for health care. "More complex care" would remain centralised.

Once in the inflamed area, such vesosomes will deliver an anti-inflammatory substance from its vesicles though a pH gradient. Vesosomes that localise to tumours have also been demonstrated. They can be used to create, in a positioned area, a different nano-environment (considering that vesosome size is about 50 - 200 nanometres) either by altering the pH or the concentration of a particular substance.

Kountoura is married to former Panellinios and Olympiacos basketball player Sarantis Papachristopoulos, her second husband. The couple have two boys Alexandros and Marios. Previously she was married to (soccer) footballer Michel Pineda. Papachristopoulos is also a magazine entrepreneur, having worked to localise risqué lifestyle and entertainment magazines such as Shock, Playboy, and Penthouse for the Greek market through the company Dafni Epikinonies (Daphne Communications).

The surgery is often performed under local anesthesia and as an outpatient procedure. An important piece of information for patients is that if they for whatever reason are not satisfied with the BAHA solution, removing the implant is easy. No other ear surgical procedure is reversible like this. By bypassing the outer or middle ear, BAHA can increase hearing in noisy situations and help localise sounds.

This is in contrast to the majority of C/D box or H/ACA box snoRNAs, which localise to the nucleolus. These Cajal body specific RNAs are proposed to be involved in the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. Not all snoRNAs that have been localised to Cajal bodies are composite C/D and H/ACA box snoRNAs.

Dharmatma is a 1975 Hindi thriller movie and the first Bollywood film to be shot in Afghanistan. It was produced and directed by Feroz Khan. The movie is the first attempt in India to localise The Godfather. The cast includes Feroz Khan, Hema Malini, Rekha, Premnath, Imtiaz Khan, Danny Denzongpa, Farida Jalal, Ranjeet, Helen, Madan Puri, Jeevan, Iftekhar, Dara Singh, Satyen Kappu and Sudhir.

There was a false assumption that if France were kept in the dark, it would still have a moderating influence and thus localise the war.John F. V. Keiger, France and the origins of the First World War (1983) pp 156-57. Just the opposite took place: without co-ordination, Russia assumed it had France's full support and so Austria sabotaged its own hopes for localisation.

Entertainment, and included actors from NIS America's localization of the Disgaea series. The team also included the Japanese voice track in the PlayStation 2 version, with a dedicated translation which preserved the original character names being created for it. The localization took two years to complete, becoming NIS America's largest localization effort to date. For the 2019 reboot, Sega brought on Yakuza 0 translators Inbound Games to localise the game.

The company designed the product in Europe and had it produced in factories in Taiwan – it was one of the first manufacturers to de-localise production to Asia. The design, and models following it, included "soft-clipping circuitry" that protects against over- driven signals, connections that allow splitting of the power amplifier section from the preamplifier, and "Full Disclosure" power ratings measuring output power under real-world loads.

Recent studies indicate that the structure of the N-terminal Shugoshin may be important for centromeric localisation, this is because it has been observed that the N-terminal fragment was the only part of the protein to localise at the centromere. Another study has shown that the N-terminal region bundles short microtubules in vitro. This suggests that the N-terminal domain has a function in bundling microtubules at the centromere.

The doublet form U12-22/U4-8 has been shown to localise to the nucleoplasm and is proposed to reside in the Cajal bodies whereas the U4-8 single domain appears to accumulate in the nucleolus. In humans the genomic location of U12-88/U4-8 is intergenic and the purified transcript has been shown to possess a methylated guanosine cap suggesting it is independently transcribed by RNA pol II.

Cattle hearing ranges from 23 Hz to 35 kHz. Their frequency of best sensitivity is 8 kHz and they have a lowest threshold of −21 db (re 20 μN/m−2), which means their hearing is more acute than horses (lowest threshold of 7 db). Sound localization acuity thresholds are an average of 30°. This means that cattle are less able to localise sounds compared to goats (18°), dogs (8°) and humans (0.8°).

By comparing the outgoing pulse with the returning echoes, the brain and auditory nervous system can produce detailed images of the bat's surroundings. This allows bats to detect, localise, and classify their prey in darkness. Bat calls are some of the loudest airborne animal sounds, and can range in intensity from 60 to 140 decibels. Microbats use their larynx to create ultrasound, and emit it through the mouth and sometimes the nose.

The globalisation strategy and the globalisation framework would provide uniform guidance for the twelve separate localisation efforts. Globalisation is especially important in mitigating extra work involved in the long-term cycle of localisation. Because localisation is usually a cycle and not a one-time project, there are new texts, updates, and projects to localise. For example, as the original website is updated over time, each already translated and localised website must be updated.

A large fixed platform, Piper Alpha sat atop Piper oilfield, approximately north east of Aberdeen in of water. It was built in four modules separated by firewalls.were not designed as blast protection walls and their function was to localise fire CAPLAN 2.6.1 The platform was constructed by McDermott Engineering of Ardersier and Union Industrielle d'Entreprise of Cherbourg, with the sections united at Ardersier before tow out during 1975, with production commencing in late 1976.

The late 1990s and early 2000s saw the birth of modern computer vision. One of the reasons this happened was due to the availability of key, feature extraction and representation algorithms. Features along with the already present machine learning algorithms were used to detect, localise and segment objects in Images. While all these advancements were being made, the community felt the need to have standardised datasets and evaluation metrics so the performances can be compared.

Mouse and yeast frataxin homologues contain a potential N-terminal mitochondrial targeting sequence, and human frataxin has been observed to co- localise with a mitochondrial protein. Furthermore, disruption of the yeast gene has been shown to result in mitochondrial dysfunction. Friedreich's ataxia is thus believed to be a mitochondrial disease caused by a mutation in the nuclear genome (specifically, expansion of an intronic GAA triplet repeat in the FXN gene, which encodes the protein frataxin.).

Since basal and lateral membranes share the same determinants, another mechanism must make the difference between the two domains. Cell shape and contacts provide the likely mechanism. Lateral membranes are the site of contact between epithelial cells, whereas basal membranes connect epithelial cells to the basement membrane, an extracellular matrix layer that lies along the basal surface of the epithelium. Certain molecules, such as Integrins, localise specifically to the basal membrane and form connections with the extracellular matrix.

Bragg was commissioned early in World War I in the Royal Horse Artillery as a second lieutenant of the Leicestershire battery. In 1915 he was seconded to the Royal Engineers to develop a method to localise enemy artillery from the boom of their firing.William Van der Kloot, Lawrence Bragg's role in the development of sound-ranging in World War I, Notes and Records of the Royal Society, 22 September 2005, vol. 59, no. 3, pp. 273–284.

Pancreatic adenocarcinomas are recognised by tumour desmoplasia, distinguished by an increase in the connective tissue that surrounds the neoplasm. Activated PaSCs in the tumour desmoplasia of human pancreatic cancers express α-SMA and co- localise with MRNA encoding pro-collagen α1I. These factors are significant contributors of the ECM proteins that compose the desmoplasia. A symbiotic relationship exists between pancreatic adenocarcinoma cells and PaSCs, which leads to an overall increase in the rate of growth of the tumour.

Finally, it reports the possibility for the input protein to be localised at each candidate site with additional information. Researchers using this tool can predict with some degree of reason, where in a cell a protein is most likely to localise to. This is because proteins are localised by cell machinery that recognises signal peptide sequences (similar to a postal address) and moves the protein the appropriate location. The signal peptide is often cleaved off after the destination is reached.

It also prevents apoptosis in several ways: it reduces mitochondrial ROS levels, and it prevents apoptosis-causing protein Bax from creating a channel with VDAC. This stops cytochrome C protein passing out through VDAC into the cytoplasm where it triggers apoptosis via a caspase protein cascade. TIGAR does not re-localise to the mitochondria and bind HK2 under normal cellular conditions, or if the cell is starved of glucose. Re- localisation to the mitochondria does not require TIGAR’s phosphatase domain.

Dauway was the co-inventor of the use of radioactive seeds in the breast to localise non-palpable breast cancers and the first in Australia to use magnetic seeds instead of radioactive seeds. This technique replaces hook- wire or needle localisation improving patient safety, outcomes and satisfaction. The method was patented by the University of South Florida while Dauway was a fellow of surgical oncology. The method has been used since 1999 and has improved with the development of modern equipment.

It not only travels across languages; it also freely mistranslates in an effort to localise. G.J.V. Prasad of JNU traced this pervasive practice as far back as the ancient Tamil text, Tolkapiyam, where it exists under the name, "mori-preyarti". The name catches the spirit if not the letter of translation as the word is understood today. It refers to "Tamilakam", the "infusion of the Tamil spirit into a deserving text", something that serves as an analogue for Senapati's "oriyanising".

The examiner passively restricts the flexion of the fingers while the examinee attempts to actively flex the thumb. A positive test is marked by restricted active thumb flexion with pain or cramping discomfort in the palmar and radial sides of the distal (lower) forearm or wrist. The magnetic resonance imaging (MRI) can confirm and localise Linburg and Comstock syndrome. As reported by Karalezli, magnetic resonance imaging was performed on all patients diagnosed with positive test, and there were tendinous connection in all cases.

A group of nuclei in pons make up the superior olivary complex (SOC). This is the first stage in auditory pathway to receive input from both cochleas, which is crucial for our ability to localise the sounds source in the horizontal plane. The SOC receives input from cochlear nuclei, primarily the ipsilateral and contralateral AVCN. Four nuclei make up the SOC but only the medial superior olive (MSO) and the lateral superior olive (LSO) receive input from both cochlear nuclei.

Anna adjusted her fee according to what the clients could afford to pay, which meant that she occasionally gave free help. She is described as a stout matron with dark piercing eyes and a dark forceful voice, and she was also known for her many black cats. In her capacity as a natural healer, she used herbal medicine: her daughter Kristina participated as her assistant in this field. As a Clairvoyant, she was often consulted for her ability to localise stolen property.

PSORT uses known signal peptide sequences to analyse and predict what an input sequence is most likely to cause a localisation to. Protein localisation is important because it supports a proposed role that a protein may have. For instance, catalase enzymes (proteins that convert peroxide into water and oxygen) should be expected to localise to a peroxisome because that is an area of high peroxide activity. By analysing a signal peptide sequence and visual localisation by GFP expression, strong evidence is obtained for this role.

Except for S1 (with a molecular weight of 61.2 kDa), the other proteins range in weight between 4.4 and 29.7 kDa. Recent de novo proteomics experiments where the authors characterized in vivo ribosome-assembly intermediates and associated assembly factors from wild-type Escherichia coli cells using a general quantitative mass spectrometry (qMS) approach have confirmed the presence of all the known small and large subunit components and have identified a total of 21 known and potentially new ribosome-assembly-factors that co-localise with various ribosomal particles.

Emilia Dauway MD, FACS, FRACS (born 11 August 1965) is an American trained surgeon who is practicing general, breast and oncologic surgery in Australia. Dauway was co-inventor of the use of radioactive seeds in the breast to localise non-palpable breast cancers and the first in Australia to use magnetic seeds instead of radioactive seeds. This technique replaces hookwire or needle localisation improving patient safety, outcomes and satisfaction. The method was patented by the University of South Florida while Dauway was a fellow of surgical oncology.

Other models assume that PIN proteins localise on the side of the cell where the efflux of auxin is the highest. These models are called "with-the-flux" models and explain the formation of vascular strands in leaves. The molecular mechanism responsible for these different behaviours of the system (with-the-flux and up-the- gradient) is not yet fully understood. Noticeably, an auxin receptor protein called ABP1 is thought to play a potentially significant role in the control of PIN proteins polarity by auxin.

In 1955 MITI began to think that Isuzu was not moving quickly enough to localise production, apparently suspecting that Rootes was deliberately causing delays.Madeley, p. 241 This may have been unfair – Rootes were planning two major changes to the Minx (a new engine, then a completely new body) and it would have made no sense for Isuzu to tool up for local production of the old engine and body. However, MITI controlled the amount of foreign currency (needed by Isuzu to pay for the CKD parts).

While Japanese commercial law allows wide latitude in translating Japanese corporate names into official English names, the merged company took the unusual step of adopting "TOMY Company, Ltd." as its official English, while using "K.K. Takara-Tomy" (株式会社タカラトミー) in Japan. Both Takara and Tomy held licenses to localise and distribute Hasbro products in Japan. The products include "The Game of Life", Blythe dolls, Magic: The Gathering, Duel Masters trading card games by Takara and Monopoly, Furby, Super Soaker and Play-Doh by Tomy.

A bhangmeter is a non-imaging radiometer installed on reconnaissance and navigation satellites to detect atmospheric nuclear detonations and determine the yield of the nuclear weapon. They are also installed on some armored fighting vehicles, in particular NBC reconnaissance vehicles, in order to help detect, localise and analyse tactical nuclear detonations. They are often used alongside pressure and sound sensors in this role in addition to standard radiation sensors. Some nuclear bunkers and military facilities may also be equipped with such sensors alongside seismic event detectors.

Superman (vol. 2) #132 (February 1998) After Jimmy and Misa had been searching for Scorn for a while to no avail Ashbury started to look for him alone only to end up as a prisoner herself. Soon thereafter Misa and Jimmy managed to localise the two of them and - aided by a strange little blue creature (later identified as a 'Fuzzlet', a creation of the Project CadmusSuperman (vol. 2) #133 (March 1998)) - enabled them to escape just before Luthor blew up the barn where the makeshift-prison was accommodated, killing his henchmen in the process.

Vezatin co-localises with E-cadherin at these cell-cell junctions suggesting that in fact it is involved within adherens junctions. E-cadherin is an important transmembrane molecule in creating and facilitating adherens junctions, particularly in epithelial cells. Furthermore, vezatin does not appear at focal adhesion sites and does not co-localise with desmogleins, which are molecules present in desmosomes, suggesting it is solely responsible for interactions within the adherens junction. Additionally, in cells lacking E-cadherin and thus unable to form cell-cell contacts, vezatin displayed a cytoplasmic distribution.

Furthermore, this company might need to adapt the product to its new buyers; video games are the best example. Now, suppose instead that this company has major offices in a dozen countries and needs a specifically designed website in each of these countries. Before deciding how to localise the website and the products offered in any given country, a professional in the area might advise the company to create an overall strategy: to globalise the way the organisation does business. The company might want to design a framework to codify and support this global strategy.

The Asquith government fell, to be replaced by that of Lloyd George, recently appointed Minister of Munitions to resolve the crisis. Watson as chairman of a six-man "Leeds Munitions Committee" made up from local industrialists, formed in August 1915, was charged by the government to immediately establish the first of 12 National Shell Filling Factories. A factory was promptly established on a greenfield site at Barnbow, close to Leeds. It resembled a small town of detached houses and huts more than a traditional factory, to contain and localise any accidental explosions.

The RS-rich domain serves to localise SON in nuclear speckles with pre-mRNA processing factors. The functional domains and specific localisation of SON in nuclear speckles has indicated its role in pre-mRNA splicing. SON also plays a key role in alternative splicing of exons. SON is required for genome stability by ensuring the efficiency of RNA splicing of weak constitutive and alternative splice sites. SON-dependent cell-cycle genes possess a weak 5’ or 3’ splice site and are dependent on SON to ensure efficient splicing and spliceosome recognition.

The target signal (if present) together with noise is then passed through various forms of signal processing, which for simple sonars may be just energy measurement. It is then presented to some form of decision device that calls the output either the required signal or noise. This decision device may be an operator with headphones or a display, or in more sophisticated sonars this function may be carried out by software. Further processes may be carried out to classify the target and localise it, as well as measuring its velocity.

The centromeric DNA is normally in a heterochromatin state, which is essential for the recruitment of the cohesin complex that mediates sister chromatid cohesion after DNA replication as well as coordinating sister chromatid separation during anaphase. In this chromatin, the normal histone H3 is replaced with a centromere-specific variant, CENP-A in humans. The presence of CENP-A is believed to be important for the assembly of the kinetochore on the centromere. CENP-C has been shown to localise almost exclusively to these regions of CENP-A associated chromatin.

When pulp testing results are inconclusive and that patients cannot localise or specify the pain or symptoms, an anaesthetic would be helpful and be used. The most posterior tooth in the area where the pain resonates undergoes anaesthesia by either infiltration or intraligamentary injection until pain diminishes. If the pain is still present, the procedure is repeated on the mesial teeth, one by one until the pain diminishes and is gone. If one can still not determine the source of the pain, the procedure will be repeated on the opposite arch.

During the Alice Springs Orogeny, reactivation occurred along the most deeply buried faults, even in instances where those faults had remained inactive during the earlier Petermann Orogeny. The major Petermann-aged structures that were not buried during renewed subsidence were inactive during the Alice Springs Orogeny. The record of reactivation tells us that the presence of pre-existing faults is insufficient to localise deformation. The correspondence between the distribution of basement fault reactivation and subsidence patterns during the Petermann and Alice Springs Orogenies implies a link between relatively thick sedimentation and long-term lithospheric weakening.

Small Cajal body-specific RNAs (scaRNAs) are a class of small nucleolar RNAs (snoRNAs) that specifically localise to the Cajal body, a nuclear organelle (cellular sub-organelle) involved in the biogenesis of small nuclear ribonucleoproteins (snRNPs or snurps). ScaRNAs guide the modification (methylation and pseudouridylation) of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. The first scaRNA identified was U85. It is unlike typical snoRNAs in that it is a composite C/D box and H/ACA box snoRNAs and can guide both pseudouridylation and 2′-O-methylation.

CKD kit as delivered to AB Nyköpings Automobilfabrik for assembly, probably a Plymouth In the automotive industry, the most basic form of a vehicle in KD kit lacks the wheels, internal combustion engine, transmission, and battery. They are either supplied as parts for assembly (a "complete" kit), or obtained from third parties (an "incomplete" kit); all of the interiors are already installed at the originating factory. The term SKD for semi-knocked-down refers to a kit with a complete, welded car body, usually coated or already painted. To gain some extra tax preferences, the manufacturer needs to further localise the car, i.e.

Numerous species of owls in the genus Glaucidium and the northern hawk-owl have eye patches on the backs of their heads, apparently to convince other birds they are being watched at all times. Numerous nocturnal species have ear-tufts, feathers on the sides of the head that are thought to have a camouflage function, breaking up the outline of a roosting bird. The feathers of the facial disc are arranged in order to increase sound delivered to the ears. Hearing in owls is highly sensitive and the ears are asymmetrical allowing the owl to localise a sound in multiple directions.

The ILJIN Group was established in 1967 to produce high-voltage electrical transmission equipment. Founder Huh Chin-kyu (허진규) wanted to localise technology to foster South Korea's economic independence, and started the company after an earlier company he worked in as engineer went bust. In addition to the production of cables and other high-voltage equipment, he ILJIN Group expanded to also produce special materials and components for electrical systems and communication equipment, and was ranked between the 50th and 60th largest companies in South Korea by assets. The company is a major producer of synthetic diamonds.

Telomeres form the terminal region of mammalian chromosomes and are essential for stability and aging and play central roles in diseases such as cancer. Telomeres have been long considered transcriptionally inert DNA-protein complexes until it was shown in the late 2000s that telomeric repeats may be transcribed as telomeric RNAs (TelRNAs) or telomeric repeat-containing RNAs. These ncRNAs are heterogeneous in length, transcribed from several sub-telomeric loci and physically localise to telomeres. Their association with chromatin, which suggests an involvement in regulating telomere specific heterochromatin modifications, is repressed by SMG proteins that protect chromosome ends from telomere loss.

In molecular biology, Small Cajal body specific RNA 11 (also known as scaRNA11 or ACA57) is a small nucleolar RNA found in Cajal bodies. scaRNAs are a specific class of small nuclear RNAs which localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA57 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs and is found associated with GAR1. ACA57 is predicted to guide the pseudouridylation of the U5 spliceosomal RNA at position U43.

In molecular biology, Small Cajal body specific RNA 14 (also known as scaRNA14 or U100) is a small nucleolar RNA found in Cajal bodies. scaRNAs are a specific class of small nucleolar RNAs which localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. U100 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure and the conserved H/ACA-box motifs. U100 is the human orthologue of mouse H/ACA snoRNA MBII-201 which is also included in this family.

In molecular biology, small Cajal body specific RNA 4 (also known as ACA26) is believed to be a guide RNA of the H/ACA box class, since it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs, and is found associated with GAR1. In particular, ACA26 is predicted to guide the pseudouridylation of residues U39 and U41 in U2 snRNA. Such scaRNAs are a specific class of small nuclear RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12.

Japanese management practises in Malaysia in the 1980s and 1990s show a different pattern of interethnic relations. Some authors suggest that the Japanese show favouritism in promotion towards Malaysian Chinese over bumiputera, due to their closer cultural background. Despite efforts to localise the management of JVs, most managers continue to be expatriates. One author, however, noted a repeating pattern in several companies she studied: there would be a single high-up local manager, an ethnic Chinese man who attended university in Japan and married a Japanese woman; however, the Japanese wives of other expatriates tend to look down on such women, and there is little social contact between them.

The sea phase of the exercise was conducted during 15-17 August 2005. It began with the deployment of maritime and air assets from participating countries to detect, localise and track the merchant ship (simulated by MV Avatar) transporting the illegal shipment of dual-use chemicals. Once located, a request was made for the ship to voluntarily divert to port for a search. When the ship’s master refused, flag state consent was sought, and given, for the ship to be interdicted and diverted to Singapore for the port search. A team from the Republic of Singapore Navy’s Naval Diving Unit (NDU) was the first to board the vessel.

Under low oxygen conditions known as hypoxia, a small amount of TIGAR travels to the mitochondria and increases the activity of Hexokinase 2 (HK2) by binding to it During hypoxia, a protein called Hif1α is activated and causes TIGAR to re-localise from the cytoplasm to the outer mitochondrial membrane. Here, HK2 is bound to an anion channel in the outer mitochondrial membrane called VDAC. TIGAR binds hexokinase 2 and increases its activity by an as yet unknown mechanism. Hexokinase 2 (HK2) carries out the following reaction: Glucose + ATP -> Glucose-6-phosphate + ADP HK2 is believed to maintain the mitochondrial membrane potential by keeping ADP levels high.

The membranous myelin sheath that surrounds and electrically insulates many nerve cell axons is particularly rich in sphingomyelin, suggesting its role as an insulator of nerve fibers. The plasma membrane of other cells is also abundant in sphingomyelin, though it is largely to be found in the exoplasmic leaflet of the cell membrane. There is, however, some evidence that there may also be a sphingomyelin pool in the inner leaflet of the membrane. Moreover, neutral sphingomyelinase-2 – an enzyme that breaks down sphingomyelin into ceramide - has been found to localise exclusively to the inner leaflet, further suggesting that there may be sphingomyelin present there.

The most radical variant, christened 'Design X', had an armour arrangement similar to the modernised battlecruiser with a pair of 16-inch and eight 4.5-inch turrets and had only minimal underwater protection, relying on tight compartmentalisation and strengthened internal bulkheads to localise damage. This yielded a ship at standard load. Friedman, pp. 363–365, 433–434 That same month a committee headed by Rear- Admiral Reginald Servaes reviewed all the proposals and the Admiralty requested a sketch design of 'X' with two 16-inch turrets, both forward of the superstructure as in the French , and a thicker waterline belt in May that the DNC designated 'X3'.

The 3' C/D domain (U4-8) was also cloned previously by Darzacq and called U91. Both the doublet (U12-22/U4-8) and singlet (U4-8) forms of this snRNA have been purified from HeLa cells. The doublet form U12-22/U4-8 has been shown to localise to the nucleoplasm and is proposed to reside in the Cajal bodies whereas the U4-8 single domain appears to accumulate in the nucleolus. In humans the genomic location of U12-88/U4-8 is intergenic and the purified transcript has been shown to possess a methylated guanosine cap suggesting it is independently transcribed by RNA polymerase II.

Four-speaker setups are the most economical way of reproducing first-order horizontal material, and a rectangular layout is most easily fit into a living room, which makes these setups the most common in domestic environments. With rectangles, there is a localisation performance trade-off: the short sides will localise more stably than the square, the long sides worse. Consequently, for predominantly frontal sound stages, Benjamin, Lee, and Heller (2008) have observed a preference for rectangular layouts over squares.Eric Benjamin, Richard Lee, and Aaron Heller, Localisation in Horizontal-only Ambisonic Systems, 121st AES Convention, San Francisco 2006 All legacy domestic hardware decoders supported rectangular layouts, usually with variable aspect ratios.

This ambidentate character of the anion means that it is able to bind via both the phosphorus and oxygen atoms depending on the nature of the centre being coordinated. Computational studies carried out on the anion such as Natural Bond Orbital (NBO) and Natural Resonance Theory (NRT) analyses can go part way to explain why PCO can react in such a manner (see Figure 1). The two dominant resonance forms of the phosphaethynolate anion localise negative charge on either the phosphorus or oxygen atoms meaning both are sites of nucleophilicity. The same applies for the cyanate anion hence why PCO is observed to have similar pseudo-halogenic behaviour.

Following the announcement of a worldwide release, controversy arose concerning the impossibility of same-sex relationships. Nintendo stated, "The ability for same-sex relationships to occur in the game was not part of the original game that launched in Japan, and that game is made up of the same code that was used to localise it for other regions outside Japan." In May 2013, it was widely reported that a bug in the original Japanese version of the game, which enabled same-sex relationships, was patched by Nintendo. This was refuted by Nintendo in a statement made April 2014, explaining that same-sex relationships were never possible, and that the patch in fact fixed a different issue.

In molecular biology, Small Cajal body specific RNA 20 (also known as scaRNA20 or ACA66) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA66 (SCARNA20) is a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis.

In molecular biology, Small Cajal body specific RNA 21 (also known as scaRNA21 or ACA68) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U12 minor spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA68 (SCARNA21) is a member of the H/ACA box class of snoRNAs that guide the sites of modification of uridines to pseudouridines. This snoRNA was identified by computational screening and its expression in mouse experimentally verified by Northern blot and primer extension analysis.

In molecular biology, Small Cajal body specific RNA 13 (also known as scaRNA13 or U93) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation of U2 and U5 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. U93 is composed of two tandemly arranged box H/ACA box sequence motifs and belongs to the H/ACA box class of guide RNAs. U93 is predicted to guide pseudouridylation of U2 spliceosomal snRNA residue U54 and residue U53 of snRNA U5.

Small Cajal body specific RNA 15 (also known as SCARNA15 or ACA45) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U1 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA45 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin- tail structure, the conserved H/ACA-box motifs and is found associated with GAR1. ACA45 is predicted to guide the pseudouridylation of residue U37 of the U2 spliceosomal snRNA.

Small Cajal body specific RNA 16 (also known as SCARNA16 or ACA47) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U1 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA47 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin- tail structure, the conserved H/ACA-box motifs and is found associated with GAR1. ACA47 is predicted to guide the pseudouridylation of residue U5 of the U1 spliceosomal snRNA.

Small Cajal body specific RNA 24 (also known as scaRNA24 or ACA12) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U6 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA12 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin- tail structure, the conserved H/ACA-box motifs and is found associated with GAR1 protein. ACA12 is predicted to guide the pseudouridylation of residue U40 of the spliceosomal U6 snRNA.

Small Cajal body specific RNA 8 (also known as SCARNA8 or U92) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U2 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. U92 belong to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin-tail structure, conserved H/ACA-box motifs and is found associated with GAR1. It is predicted to guide the pseudouridylation of residues U44 in U2 snRNA.

BLNK consists of a N-terminal leucine zipper motif followed by an "acidic" region, a proline-rich region, and a C-terminal SH2 domain. The leucine zipper motif allows BLNK to localise to the plasma membrane, presumably by coiled-coil interactions with a membrane protein. This leucine zipper motif distinguishes BLNK from its paralogue SLP-76 which, although having an N-terminal heptad-like organisation of leucine and isoleucine residues, has not been experimentally shown to have this motif. Recruitment of BLNK to the plasma membrane is also achieved by binding of the SH2 domain of BLNK to a non-ITAM phospho-tyrosine on Igα, a part of the B cell receptor complex.

Wundt contributed to the state of neuropsychology as it existed at the time in three ways: through his criticism of the theory of localisation (then widespread in neurology), through his demand for research hypotheses founded on both neurological and psychological thinking, and through his neuropsychological concept of an apperception centre in the frontal cortex. Wundt considered attention and the control of attention an excellent example of the desirable combination of experimental psychological and neurophysiological research. Wundt called for experimentation to localise the higher central nervous functions to be based on clear, psychologically-based research hypotheses because the questions could not be rendered precisely enough on the anatomical and physiological levels alone. (Wundt, Grundzüge, 1903, 5th ed. Vol.

Unsealed source radiotherapy (also known as unsealed source radionuclide therapy (RNT) or molecular radiotherapy) uses radioactive substances called radiopharmaceuticals to treat medical conditions, particularly cancer. These are introduced into the body by various means (injection or ingestion are the two most commonplace) and localise to specific locations, organs or tissues depending on their properties and administration routes. This includes anything from a simple compound such as sodium iodide that locates to the thyroid via trapping the iodide ion, to complex biopharmaceuticals such as recombinant antibodies which are attached to radionuclides and seek out specific antigens on cell surfaces. As such, this is a type of targeted therapy which uses the physical, chemical and biological properties of the radiopharmaceutical to target areas of the body for radiation treatment.

HIP1 was found to bind to Htt in an N-terminal dependent manner, and co- localise with Htt in the CNS although the nature of this interaction with respect to was not identified. It has since been found that the CAG expansion seen with results in decreased binding affinity for HIP1, thus causing disruption of HIP1’s usual function, and also an increase in free HIP1. It is likely that this decreased affinity plays a role in mediating HD pathogenesis, due to loss of cytoskeletal integrity and induction of apoptosis. HIP1’s pro apoptotic effect may involve activation of caspase-8 and a novel HIP1 protein interactor HIPPI. HIP1’s non-pathological activity includes clathrin assembly via interaction with clathrin light chains.

Small Cajal body specific RNA 6 (also known as SCARNA6 or U88) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U5 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12 U88 is found associated with both fibrillarin and Gar1p and co-localises with coilin in Cajal bodies. It is an unusual guide RNA in that it is composed of both H/ACA box and a C/D box conserved domains. It is predicted to guide 2'-O-methylation of residue U41 of the U5 snRNA.

Prichard was also concerned to challenge the development of phrenology, which attempted to localise aspects of the mind and personality to particular areas of the brain, as assessed by the size of bumps in the skull. The alternative was to locate mental disorder in temperament, abstractly located in the visceral organs or nervous system in a then modern form of humorism, while maintaining that powers of judgement were a metaphysical or religious component. Later, Maudsley discussed moral insanity as a sign of poor moral willpower or moral sense. DH Tuke asserted that while it may appear to stem from the emotions, it was often due to a weakening of the 'higher centres' of will, and he thus suggested a new name 'inhibitory insanity'.

Scandinavian cartographers from the early 15th century attempted to localise or identify Ginnungagap as a real geographic location from which the creation myth derived. A fragment from a 15th-century (pre-Columbus) Old Norse encyclopedic text entitled Gripla (Little Compendium) places Ginnungagap between Greenland and Vinland: A scholion in a 15th-century manuscript of Adam of Bremen's Gesta Hammaburgensis Ecclesiae Pontificum similarly refers to Ghimmendegop as the Norse word for the abyss in the far north.Dronke, p. 112. Later, the 17th-century Icelandic bishop Guðbrandur Thorlaksson also used the name Ginnungegap to refer to a narrow body of water, possibly the Davis Strait, separating the southern tip of Greenland from Estotelandia, pars America extrema, probably Baffin Island.Seaver, Kirsten "Maps, Myths and Men", Stanford University Press (2004) pp. 247-253.

However, as noted above it is clear that, equally, cardiac output must dictate venous return since over any period of time both must necessarily be equal. Similarly, the concept of mean systemic filling pressure, the hypothetical driving pressure for venous return, is difficult to localise and impossible to measure in the physiological state. Furthermore, the Ohmic formulation used to describe venous return ignores the critical venous parameter, capacitance. It is confusion about these terms that has led some physiologists to suggest that the emphasis on 'venous return' be turned instead to more measurable and direct influences on cardiac output such as end diastolic pressure and volume which can be causally related to cardiac output and through which the influences of volume status, venous capacitance, ventricular compliance and venodilating therapies can be understood.

Climate concerns can be integrated into local policy sectors representing economic development, urban and land-use planning, traffic, housing and tax. In getting global climate change issues within local policy, many CCP cities localise the policies that govern the controlling of GHG emissions, as opposed to the intricate problems of climate change. This way, more issues enter government local policy agendas through the delivery of preferred policy options as a means of solution to climate change problems already being addressed by the government. Local ‘hooks’ is a term often used in US cities to relate the concern of GHG emissions with local issues such as air quality. Such local issues provide the ‘hooks’ by which climate change issues are hung, prompting local governments to retain and address climate change as a localised issue.

Small Cajal body specific RNA 23 (also known as SCARNA23 or ACA11) is a small nucleolar RNA found in Cajal bodies and believed to be involved in the pseudouridylation (isomerisation of uridine to pseudouridine) of U1 spliceosomal RNA. scaRNAs are a specific class of small nucleolar RNAs that localise to the Cajal bodies and guide the modification of RNA polymerase II transcribed spliceosomal RNAs U1, U2, U4, U5 and U12. ACA11 belongs to the H/ACA box class of guide RNAs as it has the predicted hairpin-hinge-hairpin- tail structure, the conserved H/ACA-box motifs and is found associated with GAR1. H/ACA snRNAs are predicted to guide the modification of uridines to pseudouridines in substrate RNAs however, no target RNA has been identified for scaRNA ACA11.

For example, IOM scientists helped develop improved powered helmet respirators following research that showed existing devices to be heavy, cumbersome, uncomfortable and intrusive. In the 1990s, on behalf of the UK fire service, studies were carried out of the physiological and ergonomic impacts of breathing apparatus, fire hoods and protective clothing. The studies on fire hoods showed that, contrary to common belief, they did not affect the ability of firefighters to localise sound. This led to a recommendation by the UK Home Office that all fire fighters should routinely be issued with such hoods, advice which is now followed throughout the UK. The IOM has helped to assess Chemical, Biological, Radiological and Nuclear (CBRN) protective clothing for the Home Office, and has recently assisted London Fire Brigade in the ergonomic assessment for selection of new protective clothing.

Amacher herself termed them 'ear tones' until 1992, when she discovered the work of David T. Kemp and Thomas Gold and began referring to them by the psychoacoustical terminology of 'otoacoustic emissions'. It has since become clear that some of the sounds Amacher, and indeed all musicians who have exploited this phenomenon, were generating can be attributed to a particular family of otoacoustic emissions known as 'distortion product otoacoustic emissions' (DPOAE).Christopher Haworth, "Composing with Absent Sound", in Proceedings of the International Computer Music Conference 2011, University of Huddersfield, UK, 31 July – 5 August 2011, edited by Monty Adkins and Ben Isaacs, 342–45 (San Francisco: International Computer Music Association; Huddersfield: Centre for Research in New Music, University of Huddersfield, 2011). . Occurring in response to two pure tones presented simultaneously to the ear, these tones appear to localise in or around the head, as though there were a 'tiny loudspeaker inside the ear'.

Chloroplast rotation and morphological plasticity of the unicellular alga Rhodosorus (Rhodophyta, Stylonematales). Phycological research, 50(3), 183-191. In Chlamydomonas, a high-molecular weight complex of two proteins (LCIB/LCIC) forms an additional concentric layer around the pyrenoid, outside the starch sheath, and this is currently hypothesised to act as a barrier to CO2-leakage or to recapture CO2 that escapes from the pyrenoid.Yamano, T., Tsujikawa, T., Hatano, K., Ozawa, S. I., Takahashi, Y., & Fukuzawa, H. (2010). Light and low-CO2-dependent LCIB–LCIC complex localization in the chloroplast supports the carbon-concentrating mechanism in Chlamydomonas reinhardtii. Plant and Cell Physiology, 51(9), 1453-1468. The entire protein diversity and composition of the pyrenoid has yet to be fully elucidated, but thus far, a number of proteins other than RuBisCO have been shown to localise to the pyrenoid; namely, rubisco activase,McKay, R. M. L., Gibbs, S. P., & Vaughn, K. C. (1991). RuBisCo activase is present in the pyrenoid of green algae. Protoplasma, 162(1), 38-45.

The Securities Market which informally existed in Trinidad & Tobago for well over twenty years prior to the opening of the Trinidad & Tobago Stock Exchange really achieved significance in the early 1970s when the Government decided as a matter of policy to localise the foreign owned commercial banking and manufacturing sectors of the economy. The thrust of the policy was to get such companies to divest and sell a majority of their shares to nationals. Two bodies chosen to effect this policy were the Capital Issues Committee which was set up by the Ministry of Finance in July 1970 to direct developments in the primary market and the Call Exchange (an association of share dealers) which was established under the umbrella of the Central Bank in August 1965 to monitor activities in the secondary market. Parallel to this development in the public sector in the early 1970s was the rapid establishment of private institutions such as trust companies and stock broking firms to satisfy the demands of investors in both the primary and secondary markets.

After size fractionation of FCS and analysis of the lipids that bound to serum albumin, the lysophosphatidic acid (LPA) was found to be responsible for the serum activity that induced stress fibre formation. The inhibition of Rho by C3 transferase ribosylation resulted in an inhibition of focal adhesion and stress fibre assembly, but had no effect on membrane ruffling. These findings were published in Cell and cited over 4000 times. In parallel with this experiment, Hall showed that the presence of Rac, another Ras-related GTP- binding protein, is implicated in the regulation of the actin organisation in presence of extracellular growth factors. Immunofluorescence and antibody techniques were used to localise the mutant V12rac1 protein after being microinjected into the cytoplasm of confluent serum-starved Swiss 3T3 cells. The comparison with the normal cells showed that Rac1 stimulates actin filament production at the membrane, pinocytosis, and membrane ruffling. The inhibition of endogenous Rac function by mutants N17rac and V12rac1 prevented growth factor-induced membrane ruffling. In addition, the inactivation of Rho protein by ADP-ribosylation in Rac1 microinjection reduced the formation of actin stress fibres.

The original 1991 plan for the Korea Train Express (KTX) high-speed rail system foresaw an operating speed of to enable a travel time under two hours between Seoul in the northwest and Busan in the southeast of South Korea, the termini of the first line. Later, planned top speed was reduced to the maximum of existing high-speed trains on the market. Korail then ordered high-speed trains on the basis of Alstom's TGV Réseau, the KTX-I, which started KTX service on April 1, 2004, and operate at a top speed increased slightly to in November 2007. In a project South Korean government research institutes and rail industry companies launched in 1996 to fully localise high-speed rail technology, the know-how gained in the technology transfer for the KTX-I was used as the basis to develop the experimental train HSR-350x, which was to be tested at up to so that the commercial version can have a top speed of . However, the maximum speed achieved in the HSR-350x tests was on December 16, 2004; and the design and top speeds of the commercial version, the KTX-II (KTX-Sancheon) were set to be the same as those for the KTX-I.