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"sedative" Definitions
  1. having the effect of making somebody go to sleep or feel calm and relaxed

524 Sentences With "sedative"

How to use sedative in a sentence? Find typical usage patterns (collocations)/phrases/context for "sedative" and check conjugation/comparative form for "sedative". Mastering all the usages of "sedative" from sentence examples published by news publications.

Elephant sedative Carfentanil, a sedative for large animals, has led to several overdose deaths in the Cincinnati area as well, authorities said.
Shouting might merit shouting back or eventually offering a sedative.
Paramedics also gave Timpa a powerful sedative, the footage shows.
Aging brains grow more sensitive to its sedative properties, too.
When combined with CBD, it can produce a sedative-like high.
"Many users combine a sedative with a stimulant," says Bowden-Jones.
Yeah. It is a sedative, like, it is similar to Valium….
To relieve his excruciating pain, doctors administered fentanyl and a sedative.
They also detected a cough suppressant, which acts as a sedative.
Myrcene, known for producing a calming, sedative high, is dark blue.
Both it and the heart-stopping drug are supposed to be given after a powerful sedative has rendered the person unconscious, but if the sedative does not work properly, the other two drugs can cause significant pain.
Sater said the impact of the sedative was stronger than he anticipated.
Later she will be given a sedative, her face grey with grief.
Carfentanil is typically used as a sedative for large animals like elephants.
There, Mr. Bonds was given some type of sedative, his girlfriend recalled.
"Execution absent an adequate sedative thus produces a nightmarish death," Sotomayor wrote.
"Alcohol is a sedative, so this just adds to the drowsiness," Orr explained.
Carfentanil is a sedative for large animals that's not approved for human use.
The temporary injunction hinges on midazolam, a sedative produced by pharmaceutical company Alvogen.
The inmates also sued over the sedative used in the two-drug protocol.
The sedative secobarbital, branded as Seconal, made up nearly half of the prescriptions.
The singer died in June 2009 from an overdose of the sedative propofol.
The disorder can usually be controlled with a low dose of a sedative.
But midazolam, the sedative in Tennessee's execution cocktail, doesn't always render complete unconsciousness.
Indica strains are sedative, sativas are invigorating, and hybrids fall somewhere in between.
Midazolam, a sedative, has become a flash point in the death penalty debate.
After that, he was given a sedative shot and taken back to his room.
Shuler bound his legs and another paramedic administered two doses of midazolam, a sedative.
Pyongyang reported that Warmbier contracted botulism, was given a sedative, and entered a coma.
It provides another crystalline moment, but it's more of a sedative than a martini.
Nebraska and Nevada hope to soon start using the opioid fentanyl as a sedative.
Many states turned to midazolam as the sedative used in a three-drug protocol.
Because of their sedative properties, they can be potentially abused, especially if combined with alcohol.
Its use of the sedative Midazolam would, he claimed, cause him intolerable and needless agony.
Otte was among those challenging the use of midazolam as a sedative in that mix.
I like brainy, psychedelic sativas when I'm out, and sedative indicas when I'm coming down.
The chimp hung on as best he could until the sedative put him to sleep.
Patients can be understandably anxious about the operation, so they're typically given a sedative first.
When you orgasm your body releases endorphins that are shown to have a sedative effect.
Anaesthetists estimate the concentration of sedative required using calculations mainly based on a patient's weight.
"In 2013 the FDA recommended that physicians prescribe low doses of sedative hypnotics," he said.
That account led Williams' attorneys to demand an investigation and call the sedative into question.
Drugs with sedative qualities include barbiturates and benzodiazepines—and, at some doses, alcohol and opioids.
His killers tied him up and injected him with a fatal overdose of a sedative.
When they take Xanax, they won't necessarily get the same type of heavy sedative effect.
Desserts run toward milky white puddings, nice if you are looking for a mild sedative.
Poetry is a wonderful sedative because it conjures up images and emotions without a story.
Pentobarbital is most commonly used as a sedative, anesthetic or to euthanize animals, it said.
The doctor ordered a "push" on my sedative, and I succumbed to the sweet blackness.
Holding her at the end of each day is like no sedative I have ever known.
In his legal challenge, Arthur said a better alternative would be a sedative known as pentobarbital.
Mixed with other drugs, though, it can become a sedative powerful enough to stop the heart.
He said he was not in possession of the now-banned sedative when he assaulted Constand.
In it, he admitted to giving women quaaludes, a powerful sedative, as a prelude to sex.
The actor smoked cigarettes during the interview and told Colbert that he took a sedative before.
She injects him with a sedative, then slams a baseball bat near (not on) his crotch.
Kratom is unusual because it's a stimulant at low doses, and a sedative at higher ones.
People who got the sedative did report slightly more satisfaction with how the procedure went, though.
Many have turned to a less powerful, Valium-like sedative called midazolam to render prisoners unconscious.
Varga tries to talk him down, feeding a sedative to a man who has been drinking.
But, "caffeine is helpful as a stimulant to counteract the sedative effects of alcohol," Youngquist says.
He died shortly thereafter, perhaps because of the sedative, or his asthma, or because of strangulation.
Half in desperation, he reached for a surefire national sedative: Let the French talk it out.
It is a stimulant and a sedative, helping to release dopamine in the brain's pleasure centers.
The four were then given a sedative and euthanized to relieve their suffering, the NOAA said.
At issue is the use of midazolam, a sedative that does not always fully block consciousness.
They put bromide [a sedative that's deemed unfit for human consumption in most countries] in there.
In that testimony, he admitted to giving women quaaludes, a powerful sedative, as a prelude to sex.
He said he was given seven prescriptions for the now-banned sedative, ostensibly for a sore back.
You also have the option of using a sedative/anti-anxiety medication, if approved by your veterinarian.
Half were randomly assigned to hear music through noise-canceling headphones, while the rest got the sedative.
A media witness said Williams' chest heaved as he laid on the gurney after receiving the sedative.
Gray gasped and snored after the first of three drugs, a sedative known as midazolam, was administered.
Prosecutors said Khashoggi was tied up and injected with an overdose of a sedative that killed him.
She also began taking Klonopin, which is a benzodiazepine, a class of drugs that has sedative effects.
They alleged Khashoggi was tied up and injected with an overdose of a sedative that killed him.
In a community that cranks up the BPM's to manic speeds, ZULI sedative beats border on soothing.
Dr. Mader: The affect of alcohol on the brain is sedative, because it's poisonous to our cells.
Mr. Dungay died in 2015 after being restrained facedown by prison guards and injected with a sedative.
The sedative effects of my medications also mean I often oversleep and get into the office late.
Leaves of the kratom tree, native to Southeast Asia, can be used as a stimulant or sedative.
Alcohol's sedative effects tend to kick in after blood alcohol levels peak and then start to fall.
Arkansas scheduled the executions before its supply of midazolam , a sedative used in the lethal injection process, expired.
Horton said Friday that Smith was administered midazolam as a sedative for the first part of the protocol.
It's a sedative and can also be used to control seizures, which Prince suffered from as a child.
The drugs are midazolam, a sedative; vecuronium bromide, a muscle relaxant; and potassium chloride, which stops the heart.
The leaves of the kratom tree, native to Southeast Asia, can be used as a stimulant or sedative.
I begged the doctors to save me, and eventually they injected me in the butt with a sedative.
In February, the court declined to hear Arthur's appeal, which focused on Alabama's use of the sedative midazolam.
Some states, however, have turned to pentobarbital, a drug that is commonly used as a sedative during surgeries.
Benzodiazepines are a class of medication with sedative properties that are prescribed for anxiety, insomnia and other conditions.
Waseem, one of Baloch's six brothers told the police that he strangled her after giving her a sedative.
The sedative, midazolam, is a controversial replacement for anesthetics that Arkansas and other states can no longer obtain.
CBD, one of the main compounds in cannabis, can have a sedative effect on a lot of people.
Investigators were able to determine that Harper Rose was given the sedative without an order from a physician.
It does not slow the progress of the sedative, and soon the creature's chin dribbles against her shoulder.
The animals were made comfortable with a sedative and then humanely euthanized to relieve their suffering, he said.
The sedative effects will start to wear off, but your brain is still trying to maintain its equilibrium.
Both forms of catatonia typically respond immediately to low doses of a type of sedative known as benzodiazepines.
The drug was developed as a sedative by a team of scientists, including a chemist named Armin Walser.
It was first (and continues to be) used as an anesthetic, sedative, and painkiller for both animals and people.
The sedative Tennessee hopes to use, midazolam, has been implicated in several botched executions over the past few years.
Ambien is known as a sedative-hypnotic and comes in a quick-acting form and an extended-release form.
The supply it finally secured of midazolam, a sedative, is supposed to be administered by the end of April.
The case focused on the use of a sedative called midazolam as part of the lethal injection drug cocktail.
The ketamine people use as a sedative, club drug, or antidepressant is, chemically speaking, something called a racemic mixture.
Cash is a powerful sedative, however, so strong firms like J&J are best placed to end the suits.
Klonopin is an anti-anxiety sedative shown to be effective in treating sexsomnia over 70 percent of the time.
Doctors need to figure out exactly how much sedative to give them, and keep them unconscious throughout the operation.
"Chained to the Rhythm" is a song about the sedative powers of pop and the collapse of American society.
Basically, a sedative is any drug that makes you calm and sleepy; they are also sometimes known as depressants.
One of the drugs in the Arkansas mix, the sedative midazolam, has been the subject of several court cases.
"You'd have thought that attending an event celebrating patents would be akin to taking a sedative," quips one guest.
The Medical Examiner said he had a variety of drugs in his system, including a sedative, barbiturates and Ativan.
At first he thought it was side effects from the sedative or his old eyes playing tricks on him.
The Associated Press reported that Williams lurched forward 20 times in 20 seconds minutes after the sedative was administered.
Drugs, too, but the sedative effects of most anti-motion pharmaceuticals are incompatible with making your livelihood at sea.
Cannabis users also needed 14 percent more of the analgesic fentanyl and 20 percent more of the sedative midazolam.
It's a race back to the jeep to secure her in the transport cage before the sedative wears off.
That drug, the sedative midazolam, is supposed to render the inmate unconscious, and thus lead to a "quieter" death.
A toxicology report found marijuana, alcohol, "a cocaine-related substance," sedative and anti-anxiety medications and morphine in her system.
It's a sedative but it sedates the brain's control first, which can remove inhibitions and, in limited doses, reduce anxiety.
Ohio was then the first state to use a combination of the sedative midazolam and painkiller hydromorphone in an execution.
Ketamine is used as a sedative, but it induces a trance-like state, so it's also a popular party drug.
According to modern lethal injection protocol, midazolam (a sedative) is the first of three drugs given to death row inmates.
This sedative quality of green may explain why there is so much of it in hospitals, schools and work environments.
In December, Arizona also agreed in the same case to stop using the valium-like sedative midazolam, or related products.
Far from landing as satire, this version of "The Suicide" makes you want to hand everyone involved a sedative. Elegy.
And with a global problem this urgent, the very worst you could do right now is reach for a sedative.
Brown said mothers should not share a bed if they take sedative medications, are very obese or are extremely tired.
The vast majority of these "overdoses" occur as a result of combiningopioids with another sedative, such as alcohol or benzodiazepines.
Overdose deaths soared since so many people were prescribed opioids and many mixed them with alcohol and other sedative drugs.
Your subject matter can be mature, but keep it sedative in nature; avoid topics like religion, politics, sex, violence and spiders.
My doctor prescribed Fioricet, which is made up of the same ingredients as Excedrin as well as a sedative called Butalbital.
The sedative diazepam, the powerful painkiller fentanyl and the paralytic cisatracurium have never been used for lethal injections in any state.
Otte was put to death after he lost an appeal challenging the use of midazolam as a sedative in that protocol.
That protocol will include doses of midazolam, a controversial sedative deployed in several botched executions, fentanyl, and the paralytic drug cisatracurium.
These behaviors "have been reported in patients who are not fully awake after taking a sedative-hypnotic," drug information documents say.
The traditional three-drug cocktail used sodium thiopental as a sedative and vecuronium bromide or a similar compound as a paralytic.
In July 2014, Arizona officials performed a lethal injection on Joseph Wood with the sedative midazolam and hydromorphone, a potent narcotic.
Our culture has collectively decided that lavender makes for a relaxing yoga class, but the flower is not a natural sedative.
Since it was discovered in the 1960s, high doses of ketamine have been used as a sedative for animals and people.
Even after being shot by a sedative arrow in the back, he desperately tried to escape, dangling from a power line.
They continue to restrain him in the second cell, when a nurse appears to administer a shot of midazolam, a sedative.
So it is not surprising that a political entourage might turn to Ambien, a sedative widely used as a sleep aid.
Learn at least one folk lullaby; these songs offer time-tested sedative effects often composed in a five-note pentatonic scale.
The first drug is midazolam, a sedative intended to render the inmate unconscious, though critics contend it is not always effective.
Ambien's label says mixing the sedative with other depressants, including alcohol, can increase the risk of side effects like sleep driving.
The subsequent toxicology report cited a mix of Naloxone (Narcan), Butalbital, Pseudoephedrine and the prescription sedative Lorazepam (Ativan) in his system.
Murray was convicted of involuntary manslaughter for supplying Jackson with the powerful sedative propofol, which is normally used for surgical anesthesia.
The unusually busy schedule has set off last-minute appeals, as well as lawsuits over the state's use of the sedative midazolam.
The state acquired 40 vials of the sedative midazolam this month, Department of Corrections spokesman Solomon Graves said in a telephone interview.
In the early 1990s, researchers at Boston Children's Hospital stumbled on an old sedative that appeared to slow the progress of myeloma.
In January 2014, Ohio used the sedative midazolam and the painkiller hydromorphone in the execution of convicted murderer and rapist Dennis McGuire.
It's the most widely prescribed sedative-hypnotic medication on the market in the US, with millions of prescriptions sold around the world.
Officers didn't inject the sedative themselves, but the bodycam footage showed eight instances of police urging medical staffers to administer the drug.
It's similar to ketamine, a sedative known as the club drug "Special K" that's increasingly being studied and used to treat depression.
The chimp made his way to another pole, before loosing his grip and dangling from the lines as the sedative kicked in.
Accounts of his execution raised fresh concerns about whether the sedative midazolam, a Valium-like drug, is effective in lethal injection mixes.
"In the present study, we have found that Night milk, but not Day milk, produces sedative…effects in mice," the team wrote.
What they came up with, diethyl-barbituric acid (or just barbital), was vastly more potent a sedative than anything thus far produced.
Our current findings indicate the change in consciousness due to the sedative was clearly correlated with specific patterns of brain network activity.
Hops have a sedative quality, Champa told me, which can soften your skin and relax sore muscles as you marinate in them.
But I was pleased to know that the company that introduced it was fighting against its use as a sedative for execution.
As a physician, I was skeptical that Akeela's response to the sedative truly indicated whether it was time for her to go.
Finger sandwiches at a posh hotel seemed like such a fantasy, reading about it would kick in like a sedative, immediately soothing.
Also alarming is memory loss that sometimes results from "the nonbenzodiazepine sedative hypnotics, which include Ambien, Lunesta and Sonata," Dr. O'Shea wrote.
Pet euthanasia generally includes a heavy morphine-based sedative that peacefully knocks the animal out, followed by a heart stopper-chemical injection.
Inside the operating room, Maeve scooches into her chair, gets hooked up to a blood pressure machine, and is injected with a sedative.
The volunteers, all actively having suicidal thoughts, received either the sedative midazolam (intended as a control) or a low-dose infusion of ketamine.
Even though the sedative cocktails used by veterinarians have become fairly sophisticated, it's impossible to know how each individual will react to anesthesia.
The deputy public prosecutor said Khashoggi was killed following a fight, during which a decision was taken to inject him with a sedative.
Ambien is a sedative-hypnotic drug that works by slowing down brain activity so that people can go to sleep, according to MedlinePlus.
This could only happen if a cow received a dose of the sedative before its trip to the slaughterhouse, which would be unlikely.
Other side effects of the sedative can include "bizarre behaviors or doing things in your sleep that you don't remember," says Dr. Winter.
Stimulants, of course, work on dopamine receptors by stimulating them, but antipsychotics, which have a sedative effect, work in part by blocking them.
One of the drugs used by Alabama is midazolam, a sedative that has previously been involved in botched executions elsewhere in the country.
Tennessee plans called for use of midazolam as a sedative, the muscle-relaxer vecuronium bromide and then potassium chloride to stop the heart.
Critics say it's a sedative but not a painkilling anesthetic, meaning the condemned would feel tortuous pain from the drugs that come next.
For one, I'm always hesitant to take prescription medication, especially something like a sedative, on a daily basis with no end in sight.
"But so far, the main risks are that it does seem to have a sedative action, so people could get drowsy," Grant says.
An example of this is thalidomide, a sedative prescribed in the 1960s for morning sickness; later, it was found to cause birth defects.
PHOENIX (AP) — Arizona has eliminated its use of the sedative midazolam as one of the drugs it relies on in carrying out executions.
The Wayne County, Michigan Medical Examiner cited a mix of Naloxone (Narcan), Butalbital, Pseudoephedrine and the prescription sedative Lorazepam (Ativan) in the report.
Cannabis's active ingredient, THC, attaches to cannabinoid receptors in the brain, but those receptors are different than the ones sedative drugs interact with.
Kanna also activates cannabinoid receptors, particularly if it's smoked, which may be responsible for some of its sedative and euphoric effects, Giordano said.
In it, Cosby admitted he gave women quaaludes — a sedative used as a party drug in the 22015s — to have sex with them.
Chief Gallagher helped give the captive first aid, including sedative drugs and an emergency breathing tube in his throat, Special Operator Scott testified.
They argued that the two inmates' particular medical conditions made it likely that the sedative would be ineffectual, making the executions unconstitutionally painful.
"Adenosine tends to be sedative ... and one of the signals to fall asleep is that adenosine builds up in the brain," Swift said.
Background reading: • Mr. Blinder's story about how a common drug became a sedative that is now leading to a race against the clock.
Sater did not appear behind closed doors before the committee on June 21 because he overslept after he took a sedative, Sater told CNN.
He was injected with a lethal sedative and then his body was chopped up and provided to a local collaborator, according to the prosecution.
Constand alleges that the pills he gave her were actually quaaludes, a now-banned sedative, which rendered her incapacitated before he sexually assaulted her.
Khashoggi was killed during a struggle inside the consulate, injected with a lethal dose of a sedative, according to the Saudi Public Prosecutor's office.
Since drinking alcohol has a sedative effect, anything you do to stay energized might make you feel better or at least somewhat more sober.
Wednesday's execution was the first in Ohio since 2014, when Dennis McGuire was given a combination of midazolam, a sedative and the painkiller hydromorphone.
In addition, there was zolpidem, a sedative prescribed for insomnia, as well as metabolites of alprazolam and of THC, the active ingredient in marijuana.
Williams' attorneys singled out midazolam, the sedative that Arkansas and other states have used as a replacement for anesthetics that drug companies have withheld.
At question is the use of the sedative midazolam, which has been involved in several botched executions, including one in Oklahoma two years ago.
Midazolam, a sedative used only by doctors and dentists, was found in Thomas's body, and vials of the drug were discovered in Nunez's office.
And given its sedative effects on males, I wondered if morning sex would risk making me more tempted to keep hitting the snooze button.
At that time, a powerful sedative was part of the mix but since then, major pharmaceutical companies have banned sales to states for executions.
The sedative is intended to render the inmate unconscious before the person is given the synthetic opioid fentanyl and then the paralytic agent cisatracurium.
A sedative "doesn't get metabolized as quickly as the drug is stored in fat cells so they have a longer recovery time," she said.
"As the drugs that states wanted to use have become unavailable, they've shifted to drugs like midazolam and midazolam is a sedative," Dunham said.
Others are using meth as an upper to rouse themselves after using opioids, which have a sedative effect, or to help with opioid withdrawal.
In 2009, Isabell Werth, a German multigold medallist, was banned for doping her horse with fluphenazine, a sedative used in the treatment of schizophrenia.
Ketamine was first synthesized in 1962 and was used by US Army doctors on American soldiers fighting in Vietnam as a painkiller and sedative.
Today's alpine spas are updating this long tradition as the present-day search for wellness has reinvigorated the desire for their timeless sedative effects.
Nevada intends to use a sequence of three drugs for the lethal injection that's never been used before — a sedative, fentanyl, and a paralytic.
During the interview, the actor, 57, smoked two cigarettes on-air and admitted to Colbert that he had taken a sedative before the interview began.
Etomidate is an anesthetic which will be used to replace midazolam — a controversial sedative which was at the center of several botched executions in 2014.
Police officers in Minneapolis pushed emergency medical personnel to inject people in custody — including some who posed no physical threat — with the powerful sedative ketamine.
"They also work on the brain's reward pathway and increase dopamine release, which means they're inherently reinforcing, even separate from their sedative properties," she continued.
He called the pills her "friends" without telling her what they were, and admitted to giving other young women Quaaludes, a sedative, in the 1970s.
Accounts of his execution on Thursday night raised fresh concerns about whether the sedative midazolam, a Valium-like drug, is effective in lethal injection mixes.
"We know that ketamine can be a sedative and MDMA a stimulant, but judging the right balance of the two is incredibly difficult," he says.
A sedative pill like Xanax might better serve the former, and an upper like cocaine the latter, with their more targeted and "clean" physiological effects.
"Some of the sedative medications have dose-dependent side effects, meaning the higher the dose, the greater likelihood for problems," said Twardowski in a statement.
Your particular meds could be depressing your thyroid function, or acting as a sedative on your central nervous system, making you feel sluggish and slow.
But 7.1 percent of the roughly 1,000 lethal injection executions since 1890 were botched — many due to midazolam failing to act as a proper sedative.
A 53-year-old woman allegedly murdered her husband of 31 years by serving him a smoothie laced with temazepam, a prescription sedative, PEOPLE confirms.
"A lot of the time, those patients would need nitrous oxide or other sedative to help them relax," clinic staffer Veronica Renteria told The Dodo.
I hoped the world would see me as an individual who had strong opinions about our oppressive government and the sedative qualities of organized religion.
The combination includes the sedative diazepam, which is often sold under the brand name Valium; the muscle relaxant cisatracurium; and fentanyl, according to the statement.
Finally, after being shot with a sedative dart, he fell headlong from a tangle of power lines into a blanket held by a dozen workers.
Republican Governor Asa Hutchinson set the execution schedule because one of the three drugs used in Arkansas executions, the sedative midazolam, expires at month's end.
Aside from being a sedative, Ketamine has dissociative properties, which means it can make you feel disconnected from your body and the world, Levine says.
Nevada corrections officials revised their lethal injection protocol last week, saying they were switching to midazolam to replace expired prison supplies of another sedative, diazepam.
Use of iPads or other tablet devices is a non-pharmacologic tool which can reduce perioperative stress without any sedative effect in paediatric ambulatory surgery.
Like in Nevada: On Wednesday, the state will try a brand-new combination of the sedative midazolam, the synthetic opioid fentanyl, and the paralytic drug cisatracurium.
The state managed to find new drugs and rewrote its injection protocol, but it kept using midazolam, a sedative that's been found in several botched executions.
Despite the raging controversy among pharmacologists and death penalty opponents over the sedative midazolam, Ohio plans to use it to knock Phillips out during his execution.
" Lembke explains that substances that release high amounts of dopamine swiftly tend to be more addictive, "especially for those who are vulnerable to the sedative effect.
Originally and still used as a sedative for people and animals, it's also a common party drug, since it can cause a euphoric if disorienting high.
Video The use of ketamine as an emergency sedative skyrocketed in recent years, rising from just two occasions in 2010 to more than 60 last year.
At the same time, FDA testing of Lean Lean Syrup found it did contain an antihistamine and sedative called doxylamine, which isn't mentioned on the label.
When you drink alcohol, it works on a number of neurotransmitters in the brain such as GABA which is responsible for the sedative effects of alcohol.
He also said he had previously obtained Quaaludes, a powerful sedative, with the intention of giving them to women with whom he wanted to have sex.
The entire procedure only takes about 10 or 15 minutes, and patients can be administered a mild sedative and pain medication so it won't bother them.
The jury heard portions of Cosby's prior testimony where he admitted to giving women Quaaludes (a strong sedative and recreational drug) before having sex with them.
She gives Kira the sedative, but as she looks at her, Kira transforms into her past self — the child whose life was eaten away by neolutionists.
Khashoggi was killed on October 2 by an injection that contained a sedative overdose, deputy public prosecutor and spokesperson Shaalan al-Shaalan told reporters on Thursday.
The following year, given a sedative to undergo a CT scan at a Los Angeles hospital, Radner went into a coma and did not regain consciousness.
St. Joe's pediatricians used a non-opioid protocol including a nasal spray of ketamine, a powerful drug which, in low doses, has analgesic and sedative properties.
This is the great sedative of Australian politics: dulling our attention, rendering all else some indecipherable white noise we only vaguely register before we fall asleep.
"Sedagive?" he barks, referring both to an earlier joke about a sedative and the current situation, and turning each syllable into a note of aggravated disbelief.
That represents an important cost saving for the clinics in which Mosso works; sedative drugs such as fentanyl and midazolam are "very, very expensive", he says.
At 218, he hired Samantha Gailey as a model, gave her champagne and the powerful sedative Quaalude, and had sex with her at Jack Nicholson's house.
But to leave it at that, to see meditation in the age of Trump as a kind of sedative, is to give the practice short shrift.
In fact, these mixes are more deadly than taking opioids alone, though less so than mixing drugs that both have sedative effects, like benzodiazepines and opioids.
" Musk admitted to sometimes taking Ambien, a sedative used for short-term treatment of insomnia, because "it is often a choice of no sleep or Ambien.
A federal appeals court Thursday upheld a patent ruling that allowed healthcare company Fresenius Kabi to launch a generic version of Pfizer Inc's sedative Precedex Premix.
Such encounters temporarily free us from civilization's sedative effects, and startle our consciousness about the improbable, fundamental fact that we too are animals and we exist.
Cosby didn't admit that he gave the sedative to women without their permission, but it certainly seems damning in light of all the accusations against him.
Assessments of the recordings by intelligence officers in Turkey and elsewhere suggested Khashoggi may have been injected with a sedative and then suffocated, the report said.
The caffeine in them masks the effects of alcohol, in particular the sedative effects, by keeping the person awake and alert longer, but still just as drunk.
As the lethal dose of the sedative pentobarbital began taking effect, he twice used an obscenity to say he could taste it and that it was burning.
Irick and other death row inmates have been part of a lawsuit that seeks to block use of Tennessee's lethal injection mix, which contains the sedative midazolam.
Hitting Bottom "Stray" is a literary coming to terms with her parents' substance abuse, as well as her own periods of heavy drinking, cocaine and sedative use.
In January, however, Ohio's Department of Corrections obtained the drugs needed for a new three-drug lethal injection protocol, which still relied on midazolam as a sedative.
Arkansas contends it must act quickly because one of the drugs in its lethal injection mix, the valium-like sedative midazolam, expires at the end of April.
Vaillancourt's arrest follows a medical examiner's autopsy, which found that Harper Rose had high concentrations of diphenhydramine, a sedative, in her body and died of diphenhydramine intoxication.
Saudi prosecutors on Thursday offered yet another version of events, saying Khashoggi was killed by a lethal dose of a sedative in an abduction attempt gone wrong.
Parks had switched the Norths' insurance, for reasons she never explained, and Rennie began seeing new doctors, who prescribed Valium, Prozac, the sedative Temazepam, Oxycodone, and Fentanyl.
The girl, who has a hearing disability, was given a sedative by injection before she was assaulted in the generator room in her building's basement, Rajendran said.
Alvogen, another drug maker, sued the state of Nevada in July, claiming that the state had illegally acquired midazolam, a sedative, for the execution of Scott Dozier.
The state was planning to use three drugs -- midazolam (a sedative), fentanyl (the high-potency opioid) and cisatracurium (a paralytic) -- to execute Scott Dozier on Wednesday night.
Image: Janssen PharmaceuticaThis week, the Food and Drug Administration approved Johnson & Johnson's Spravato, the nasal spray version of a ketamine-like sedative, for certain cases of depression.
With the state's supply of the sedative midazolam due to expire at the end of the month, the proposed schedule came to resemble a lethal clearance sale.
A clinical trial to test them found that they significantly reduced the proportion of patients reporting hospital-related sleep disruptions, and they cut sedative use in half.
Critics of the drug have argued that midazolam, a sedative, fails to render a prisoner sufficiently insensate to the pain of other ingredients used in lethal injections.
In Tennessee, the protocol calls for the injection of three drugs: midazolam, a sedative; vecuronium bromide, which paralyzes the inmate; and potassium chloride, which stops the heart.
According to Arkansas' Lethal Injection Procedure, each man will first get an intravenous injection of a sedative called midazolam, a benzodiazepene—the same class of drugs as Valium.
Tennessee, like several other states, employs a three-drug lethal injection protocol: first a sedative akin to Valium, then two incredibly painful drugs — a paralytic and potassium chloride.
Unlike the previous trial, O'Neill hinted that he may block prosecutors from introducing Cosby's deposition in which he admits to obtaining and giving women quaaludes, the powerful sedative.
A prior study conducted at Hennepin comparing ketamine with another common emergency sedative, haloperidol, showed that complications occurred in 49% of patients receiving ketamine versus 5% getting haloperidol.
The actor smoked not one, but two cigarettes during his Late Show with Stephen Colbert interview, and admitted to host Stephen Colbert that he took a sedative before.
His wife, Elin Nordegren, gave the officers two pill bottles to show what the golfer had taken — one for the sedative Ambien, and another for the narcotic Vicodin.
As PEOPLE reported early Friday, marijuana, alcohol, "a cocaine-related substance," sedative and anti-anxiety medications and morphine were found in her system, according to a toxicology report.
" On my bedside table was a bag of red pills, each containing 2mg of etizolam—an extremely potent sedative available legally at the time as a "research chemical.
According to the report, obtained by TMZ, the singer had Naloxone (Narcan), Butalbital (sedative), Lorazepam (Ativan), Pseudoephedrine (decongestant) and barbiturates in his system at the time of death.
Speaking under oath, Cosby said he acquired seven prescriptions for Quaaludes, the powerful sedative, in order to give them to women with whom he wanted to have sex.
The state used etomidate as one of three drugs in the lethal injection, marking the first time the sedative has been used in an execution, according to WJAX.
That kind of honest admission is even more concerning when you remember Jean is actually on medication, an anti-anxiety sedative (which she's seemingly prescribing to herself, illegally).
In August, Florida executed Mark Asay using etomidate, a drug that had not previously been used in the US for lethal injection in place of the sedative, midazolam.
Some doctors offered patients the option of taking sedative medications, which would not keep them unconscious like general anesthesia, but might help them relax or go to sleep.
They may swallow a liquid sedative or inhale laughing gas and once it kicks in, they will be conscious but calmer, so the dentist can do extensive work.
After all, you dug deep, and found the motivation to get your sweat on — even when the odds were against you, thanks to the sedative effects of alcohol.
And 17 or so years later, another brother, seeking to defend the family honor against her online antics, will spike her milk with a sedative and strangle her.
She told him that she was given four at the time of the procedure: propofol, a sedative; fentanyl, a pain killer; cefazolin, an antibiotic; and ondansetron, for nausea.
Thankfully, after several minutes of debating whether it was safe to close my eyes, the drug's sedative effects seemed to override the anxiety and paranoia, and I fell asleep.
When adenosine receptors are normally activated, they tend to cause sedative effects, such as reducing your heart rate and suppressing the release of other neurotransmitters (including glutamate and dopamine).
The unprecedented schedule was set by Republican Governor Asa Hutchinson because a drug in the state's mix for lethal injections, the sedative midazolam, expires at the end of April.
In 1971, Scott Asheton, who played drums in the group, got blitzed on the sedative secobarbital and drove a tall truck full of rented gear under a low bridge.
All we had to do is follow her perfect voice: Equal parts embracing and sedative, it was so smooth that it made my scalp feel like it was melting.
In December, Arizona agreed in the same case to stop using the valium-like sedative midazolam, or related products, as a part of a drug protocol for lethal injections.
Noga was selling kava, a mildly sedative and euphoric drink consumed across the Pacific Islands, and poi, a traditional Hawaiian food made out of taro, outside of the event.
It received FDA approval for use in humans in 1970, and shortly after, Army doctors used the drug on American soldiers fighting in Vietnam as an analgesic and sedative.
According to a report obtained by TMZ, Cornell had Naloxone (Narcan), Butalbital (a sedative), Lorazepam (Ativan), Pseudoephedrine (a decongestant) and barbiturates in his system at the time of death.
Death penalty critics have argued for years that midazolam is a sedative -- not an anesthetic -- and that the condemned would feel tortuous pain from the drugs that come next.
Its explicit aim is to bring about in your child — through the sedative effects of repetition, through extreme dullness, through strategically staged yawns — a state of narrative-induced anesthesia.
A lower court paused the state's use of a lethal sedative because of the potential of a painful death, but last month a federal appeals panel overruled their decision.
For this reason, I was very much ready to administer a mild sedative to both our kids at the start of our (sadly unavoidable) family trip to South Africa.
The sedative I'd been told to swallow on arrival was muting any potential pain, and I gleefully picked a silver faux-rotary number to hang from our kitchen wall.
My daughter was given a double dose of sedative to help with the pain and anxiety of 10 stitches to the forehead; I wish they'd offered me some, too.
Indica tends to have more exotic aromas and is more relaxing, almost like a sedative, while sativa, with its greener, almost piney flavor, offers a more active, productive high.
The state's rationale for its intended spree is morbidly pragmatic: The stock of one of its three execution drugs, the sedative midazolam, will expire at the end of April.
This year, those same eight death row inmates in Arkansas challenged the state's use of midazolam, a controversial sedative that's been used in botched executions in Ohio, Oklahoma, and Arizona.
November 15, 2018 - The Saudi Public Prosecutor's office releases additional details of Khashoggi's death, including that following a physical altercation, he was injected with a lethal dose of a sedative.
"This is very disturbing, but not at all surprising, given the history of the risky sedative midazolam, which has been used in many botched executions," Nolan said in a statement.
Still, the study seems to show that there are no major added risks on people's mental state during these procedures if they listen to music instead of taking a sedative.
Massey had a blood-alcohol level of 0.15 percent, nearly twice the legal limit to drive and traces of midazolam, a prescription sedative often used before medical procedures, Wilkins said.
They and death row inmates nationwide had challenged executioners' relatively recent use of the sedative midazolam -- a drug that some states started using because manufacturers restricted access to other drugs.
The new drug, etomidate, is a sedative that is supposed to prevent pain, but doctors say it is short-lasting and painful when it's injected, according to Asay's court filings.
Jackson, who had the medical condition vitiligo that lightened the color of his skin, died in June 2009 at the age of 50 after an overdose of the sedative propofol.
In what was then a sealed deposition, Cosby acknowledged he had obtained Quaaludes, a sedative, in order to give them to young women with whom he wanted to have sex.
The police report listed four medications Woods told officers he was taking — Vicodin (an opioid pain reliever), Torix (an anti-inflammatory medication), and an un-identified sedative or sleep agent.
Many states have experimented with new drug combinations, sometimes with disastrous results, such as the prolonged execution of Joseph R. Wood III in Arizona in 2014, using the sedative midazolam.
Linda had been questioned and ruled out as a murder suspect, but that didn't exclude the possibility of a more benign reason for supplying her insomniac husband with a sedative.
They plan to use a sedative drug called midazolam, which has been shown in studies to produce a kind of amnesia that can temporarily prevent people from forming new memories.
Pentobarbital, another sedative, accounted for 30 percent of the prescriptions, but its use dropped after its manufacturer stopped selling the drug to keep it from being used in state executions.
Patients are prescribed both types of drugs to combine the sedative and anti-anxiety effects of one with the painkilling effects of the other -- particularly for those with chronic pain.
It might seem like taking a sedative opioid with a pick-me-up drug like coke or meth would reduce overdose risk, because some effects might cancel each other out.
A "Sleep-inducing pill?" sounds like we are supposed to be thinking about a sedative, but in this puzzle, the word "pill" means someone who is annoying or boring. 65A.
Tito now faces his fears with relative calm, helped along by a mild sedative two hours before an appointment, along with cream cheese or peanut butter snacks once he arrives.
There are additive blood-thinning effects (fish oil or vitamin E taken with Coumadin), additive sedative effects (valerian used with antihistamines) and the prolongation or intensification of drug effects (St.
The manufacturer, Alvogen, accused the state and its department of corrections of using deception to acquire a supply of Alvogen's midazolam, a sedative used in a number of botched executions.
Last week, the Nevada Department of Corrections announced that it would execute Dozier using an previously-untested combination of the paralytic cisatracurium, the synthetic opioid fentanyl, and the sedative midazolam.
Pfizer moves to block its drugs from use in executions Smith's lawyers argued that midazolam is just a sedative, not a barbituate that would more reliably render him unconscious like pentobarbital.
The state faces legal challenges to its reasoning that it needs to carry out the executions before the expiry date on its stock of a controversial sedative used in lethal injections.
In the deposition, Cosby admitted he had previously obtained prescriptions for Quaaludes, a powerful sedative, with the intention of giving the drugs to women with whom he wanted to have sex.
Arizona: After the state's end-of-year ban on the use of Midazolam -- the current, but controversial, sedative of choice in executions across the country -- they are scrambling for an alternative.
The rushed schedule was prompted by the expiration at the end of April of the state's supply of the Valium-like sedative midazolam, which is used to sedate prisoners before death.
Only the virus for German measles and the banned sedative Thalidomide, which had been used to prevent morning sickness, were comparable to Accutane as causes of birth defects, Dr. Lammer said.
Quitting drinking can be really tough, and a number of patients have told her that they miss it, whether for social reasons or because alcohol's sedative effects helped ease their anxiety.
However, this team later published a paper stating dose was not a significant factor for overdoses, but concomitant sedative-hypnotics such as benzodiazepines and muscle-relaxants were common in most overdoses.
In the sworn testimony, Cosby admitted to having sexual relations with Constand and to obtaining the sedative drug Quaaludes to give them to women with whom he wanted to have sex.
The brain adapted to the sedative effect of the drugs to the point where patients would pop a calming pill just to treat the symptoms of withdrawal since the previous dose.
As supplies of execution drugs have grown more scarce, at least seven states have turned to midazolam, a powerful sedative that is widely available, but controversial when used in lethal injections.
Hutchinson has said the state must act quickly because the efficacy date for one of the chemicals in its lethal injection mix, the sedative midazolam, expires at the end of April.
Though Barr said she had quit Twitter, she came back early Wednesday morning to apologize, and said the Ambien — a sedative often used for insomnia — is what led to the offensive tweet.
Lynne U. Sneddon, Ph.D.Director of Bioveterinary Science, University of LiverpoolIn small doses some strains of cannabis can act as a sedative but higher doses and some strains actually act as a stimulant.
Adams also explained Justin was trying to "score Xanax," a sedative that can treat anxiety and panic disorder, but is also known to cause paranoia, impair memory and judgment and suicidal ideation.
"This hormone among many other feel-good hormones has been said to act as a sedative to reduce the time it takes to fall asleep," Lastella said when the project was announced.
Photo: Ian Waldie (Getty Images)The U.S. Food and Drug Administration has approved the first new kind of depression treatment seen in decades, a nasal spray drug based on the sedative ketamine.
"I will say [Kate's suicide] was not unexpected by me," Brosnahan Saffo wrote in her exchange with The Star, to which she admitted taking a sedative before speaking with her hometown newspaper.
Versed is a sedative typically prescribed to reduce anxiety but medical personnel at the CIA believed that it could also be administered to prisoners to influence their state of mind during questioning.
The pharmaceutical company Alvogen filed a challenge on Wednesday accusing the state of Nevada of surreptitiously obtaining the sedative Midazolam and saying that it did not want the drug used in executions.
He did, however, give a deposition in which he admitted that he had obtained Quaaludes, the powerful sedative drugs, to give to women he wanted to have sex with in the past.
In low doses, it acts as a slight stimulant, and in higher doses it acts like more of a sedative, one reason kratom has also been hailed as an anti-anxiety drug.
You see, Arkansas' supply of Midazolam, a powerful sedative that has a very bad record in fully bringing the "strapped-in" to unconsciousness to properly ensure painless death, is about to expire.
In December of 2015, a team of officers forcibly moved him from one cell to another after he refused to hand over a snack, and a nurse gave him a chemical sedative.
There were not, for example, last-minute questions about his competency or Alabama's reliance on a lethal injection protocol that includes midazolam, a sedative whose use in executions has been bitterly disputed.
Local media reported that Warekar had laced his family's food with a sedative before slaughtering them, but Kabdule said this was unconfirmed and samples taken from the house are still being analyzed.
Today's show looks at how a sedative more powerful than Valium has become central to executions around the U.S. Listen from a computer, on an iOS device or on an Android device.
A new study being published by the World Federation Of Societies of Anaesthesiologists (WFSA) claims that giving a child an iPad to use before surgery can be as relaxing as a sedative.
Leaves of the kratom tree, native to southeast Asia, can be used as a stimulant or sedative, and the U.S. Drug Enforcement Administration has listed it as a "drug and chemical of concern".
In 1996, a pair of twin brothers dubbed the Rohypnol Romeos by People magazine were arrested after cops found seven boxes of the sedative in their apartment along with videos of their crimes.
New information that became available Wednesday indicated that in fact they were given an anti-anxiety medication or sedative and wrapped on stretchers as the expert divers ferried them through the cave system.
Some of these combinations, especially those that involve sedative drugs, can lead to levels of impairment that are far out of proportion to what would have happened if the drugs were taken separately.
Once Game Warden Timothy Wenrich with the Pennsylvania Game Commission arrived at the scene, "the bear was sedated and safely lowered from the tree once the sedative took effect," the police department wrote.
A toxicology report from her autopsy showed the presence of heroin, clonazepam (a sedative to treat seizures or anxiety), topiramate (for nerve pain) and fluoxetine (for depression) in her body when she died.
Leaves of the kratom tree, native to southeast Asia, can be used as a stimulant or sedative and the U.S. Drug Enforcement Administration has listed it as a "drug and chemical of concern".
The backlash over the use of ketamine as a sedative prompted the police to issue an order in May to "never suggest or demand" that paramedics sedate a suspect during a police call.
The state has said it had to act quickly because one of the drugs in its difficult-to-obtain lethal injection mix, the valium-like sedative midazolam, expires at the end of April.
In the civil deposition, he admitted that he had previously obtained prescriptions for Quaaludes, a powerful sedative, with the intention of giving the drugs to women with whom he wanted to have sex.
Hospitals in Illinois, Indiana, Maryland and Virginia received mislabeled doses of pain relievers including fentanyl, morphine sulfate and midalozam, the powerful sedative often used for anesthesia and in some states in lethal injection.
Tim Pawlenty said Handel's win provides the party with "huge relief and somewhat of a political sedative" heading into 2018, when Democrats are eager to try to win back control of the House.
"For persons taking zolpidem, driving after they have been awake for an extended period of time can help the sedative to become metabolized and have a lower concentration in the blood," Booth said.
Other sedative and hypnotic drugs can also cause these reactions, and some Ambien-induced odd behaviors — eating buttered cigarettes, sleep driving, playing online poker — are pretty scary, as Forbes' Matthew Herper pointed out.
Benzodiazepines include drugs like Xanax, Klonopin, and Valium, the drug immortalized in the Rolling Stones track "Mother's Little Helper" for its sedative and calming (albeit, at least in the song, ultimately deadly) properties.
As a reward for honoring your American right, and also as a sort of sedative to see you through the next 24 hours, the San Francisco Zoo is live streaming its red pandas.
New information that became available Wednesday revealed that in fact they were given an anti-anxiety medication or sedative and wrapped on stretchers as the expert divers ferried them through the cave system.
Although it can be used as a sedative and anticonvulsant by physicians, just 10 grams of Nembutal is enough to induce respiratory arrest and cause death in humans within a matter of minutes.
In that case, Harris allegedly sold drugs to a man named Sonny Priest, who died the week before Christmas in 153 from ingesting a combination of cocaine, heroin, fentanyl, and the sedative alprazolam.
A receptionist at his clinic in the early 2000s, Ms. Schmaing said she watched Dr. Koller throw a cat onto the ground and step on its head to inject it with a sedative.
In addition to raising these issues in his appeals to the justices, Mr. Lee challenged Arkansas's lethal-injection drug protocol, which incorporates a sedative, midazolam, that has been implicated in multiple botched executions.
During the trial, the prosecution called one expert who testified that victims' accounts are often disjointed and inconsistent, and another who said that Benadryl, in a high dose, could be a powerful sedative.
Even better, she'll never have to leave the comfort of her own bathroom to get polished skin and a moment of relaxation (the scent of jasmine tea is proven to have sedative effects).
What's more, the state's rationale for the schedule — the expiration date on its supply of midazolam, a common sedative — is faulty, because the drug shouldn't be used in executions in the first place.
As states struggle to secure their first- or even second-choice lethal injection drugs, Florida tried out a new sedative called etomidate when it executed 53-year-old double-murderer Mark Asay, in August.
A toxicology report revealed the Cornell — who had battled addiction throughout his life — had Naloxone (Narcan), Butalbital (a sedative), Lorazepam (Ativan), Pseudoephedrine (a decongestant) and barbiturates in his system at the time of death.
The Arizona Department of Corrections' supply of midazolam, a sedative, expired on May 31 and it has not been able to replace it, state lawyers said in the filing in Phoenix's U.S. District Court.
Campbell's new appeal to the U.S. Court of Appeals for the Sixth Circuit Court, however, technically centers around a different issue: the use of midazolam, a sedative that's meant to render an inmate unconscious.
A toxicology report revealed the Cornell — who had battled addiction throughout his life — had Naloxone (Narcan), Butalbital (a sedative), Lorazepam (Ativan), Pseudoephedrine (a decongestant) and barbiturates in his system at the time of death.
According to a new study out this week, patients who listened to music before having anesthesia injected into them had their level of anxiety lowered as much as those who took a mild sedative.
" And after Oliver inquired if she took the sedative before a fight scene, the actress further explained, "I woke up and I thought it was something else, it was like normal to take it.
The US Supreme Court eventually decided to weigh in on whether use of the sedative constituted "cruel and unusual punishment," but the justices ultimately decided midazolam was fair game in a 5–4 decision.
Heedless to the after-effects of opium use, doctors had seized upon its sedative-like properties to develop it into a concentrated product they were sure would be a great boon to mankind: morphine.
Until last month, the police had no policy for using the drug, which the department manual classified as a "date rape drug" because it is a powerful sedative that can erase or alter memory.
" The upshot of those efforts, he said, was that "states are reduced to using drugs like" the sedative midazolam, "which give rise to disputes about whether, in fact, every possibility of pain is eliminated.
The decision by the Arizona Department of Corrections to abandon the drug, a sedative known as midazolam, came in a settlement agreement as part of a lawsuit over the state's execution drugs and procedures.
The dates were placed so closely together because of another logistical issue: Arkansas's supply of midazolam, a sedative used in a three-drug injection method, has an expiration date at the end of April.
Doctors are divided on whether or not to use drugs such as Klonopin, which have sedative effects; some feel it brings the patient too deep into phase 3 sleep, which could trigger sleepwalking anyway.
The two men are among the eight death row inmates whom the state chose to execute this month before its supply of midazolam — a sedative used in a three-drug lethal injection protocol — expires.
According to Birmingham News reporter Kent Faulk, Smith moved his lips after receiving an injection of midazolam, the third-choice sedative that most death penalty states are using in the absence of stronger barbiturate drugs.
All that said, the sauce remains undeniably popular in the bedroom and not without reason: Booze––when used in moderation––has sedative effects that help chill us out and lower inhibitions, for better or worse.
The Calm supplement is a 100-percent natural mix of valerian root and passion flower, forming a natural sedative that can temper your dog during moments of high-stress, separation anxiety, mood changes, or irritability.
Intent on keeping things on schedule, a handful of states in recent years have tried out a new cocktail that includes midazolam, a common sedative that's supposed to knock people out for a painless death.
In 2015, they upheld Oklahoma's use of a sedative tied to two botched executions after complaining at oral arguments that the state only used it because an activist-led embargo had cut off other supplies.
The doctors and nurses rushed in, and after the convulsions—which took about 60 seconds—were over, they gave her a generous shot of sedative to put her to sleep and calm down her brain.
William McBride was among the first doctors to sound an alarm about thalidomide, the sedative found to cause birth defects, but his later career was marred by accusations of falsified research results and other misconduct.
But except for people with short-term sleep-disrupting issues, like post-surgical pain or bereavement, these sedative-hypnotics have a time-limited benefit and can sometimes cause more serious problems than they might prevent.
Whether injured during workouts or mid-race, most met their end the same way: A broken bone, an emergency crew rushing to their side, a shot of a heavy sedative followed by a lethal injection.
According to the settlement filed late on Monday in a federal court in Phoenix, Arizona "will never use again" the sedative midazolam, or related products, as a part of a drug protocol for lethal injections.
TUCSON — When a chemist named Armin Walser helped invent a sedative more powerful than Valium more than 40 years ago, he thought his team's concoction was meant to make people's lives easier, not their deaths.
Gruesome recording According to the report -- which cites evidence from Turkish and other intelligence agencies -- after entering the consulate, Khashoggi was injected with a sedative and then his head put inside a plastic bag and suffocated.
Robert Dunham, executive director of the non-profit Death Penalty Information Center, said on Monday it was unclear if the appeals court case would ultimately resolve the debate over the use of the sedative in executions.
Following the second incident, the two von Auersberg children hired an investigator, whose search of the mansion turned up a black bag reportedly containing three hypodermic needles, which showed traces of insulin along with a sedative.
According to the study, mice dosed with night milk were less inclined to explore during an open field test, which the team believes reflects reduced central nervous system activity and the sedative effect of the milk.
Twardowski and his team hope to continue studying the link between cannabis and sedative tolerance (including its effect on deep sedation), as well as whether cannabis can also affect how pain is managed following medical procedures.
A urine test revealed hydrocodone and hydromorphone, two opioid pain medications; alprazolam, prescribed for anxiety and panic disorders; zolpidem, a sedative prescribed for insomnia; and metabolites of alprazolam and of THC, the active ingredient in marijuana.
As we reported ... Roseanne tried blaming the sedative for her racist tweet aimed at former Obama adviser Valerie Jarrett, in which she called her a baby born out of the 'muslim brotherhood & planet of the apes.
Prosecutors say Khashoggi was tied up and injected with an overdose of a sedative that killed him, then his body was dismembered and removed from the consulate by five people and given to a local collaborator.
" As the character lies atop the monster he has created, he barks the nonsense word "sedagive," referring to an earlier joke in the scene in which his assistant misinterpreted an attempt to mime the word "sedative.
It entailed a barbiturate that acts as a sedative and painkiller, a neuromuscular blocking drug that prevents almost all of the body's muscles functioning and, finally, a lethal dose of potassium chloride, which stops the heart.
Many of the comments recalled a 2013 incident when the Australian men's freestyle relay team were suspended for using a sedative banned by their national Olympic committee (AOC) in a bonding session before the London Games.
But the drug that led to the postponement of the execution on Wednesday was not fentanyl but midazolam, the sedative in the three-drug cocktail, whose use in executions has been bitterly disputed for different reasons.
The most restrictive form involves simultaneously binding a person's arms and legs with leather straps called four-point restraints, but hospital staff can also employ soft Velcro straps, roll belts, or sedative drugs to subdue patients.
The stay was issued to give Borden time to challenge the use of the sedative midazolam to carry out his execution by lethal injection, said Christine Freeman, executive director of the public defenders office representing Borden.
In July, the Associated Press reported on a 2005 deposition in which Cosby said he had purchased Quaaludes, a type of sedative, with the intent of giving them to women he planned to have sex with.
The EMTs, who had arrived in an ambulance with basic life support functions on board, made the decision to call for a second, more advanced ambulance with capabilities to administer Ahmodu a sedative because he was distressed.
Death penalty critics have long argued that though midazolam is a sedative, it is not a painkilling anesthetic like drugs once commonly used, and that the condemned would feel tortuous pain from the drugs that come next.
Vicky Cornell became concerned when her husband, the frontman for Soundgarden and Audioslave, told her by phone about his dose of the prescription sedative, which can be used to treat anxiety, she told CNN in a statement.
Mel Pohl, chief medical officer of the Las Vegas Recovery Center, told the Review-Journal that the drug, despite being a sedative, has been associated with aggressive—even violent—behavior, particularly in people with underlying aggression problems.
It's placed on the forehead for one or two hours during a headache and sends electric pulses through the skin into the trigeminal nerve in the face, calming the main culprit for pain with a sedative effect.
Wolf articulated the feeling that roiled in my belly alongside an unfulfilling banquet of fat-free foods: "Dieting is the most potent political sedative in women's history; a quietly mad population is a tractable one," she wrote.
If you go anyway, because you really need somebody in a white jacket to tell you that you're not going to die, they'll likely just "give you a sedative and have you sleep it off," Browne adds.
Media witnesses reported seeing Williams "manifesting signs of vigorous consciousness such as lurching, jerking, convulsing, and coughing during the course of the execution," long after the controversial sedative midazolam should have taken effect, according to the motion.
Coyle, his successor, fired the wrestling coach J Robinson — who led Minnesota to three national championships — in September 2016 for allegedly interfering with police and university investigations into whether his wrestlers had sold Xanax, a prescription sedative.
The settlement is the most recent chapter in the story of thalidomide, the notorious drug that was developed by a German company and marketed around the world in the 1950s as a sedative and anti-nausea treatment.
Arkansas had originally planned to execute eight men over 11 days, before its supply of the controversial sedative midazolam expired at the end of the month, but a sprawling legal saga cut the state's goal in half.
He cited Cosby's admission in a 2005 deposition that he had obtained Quaaludes, a sedative that was a popular recreational drug in the 1970s, intending to give them to young women in order to have sex with them.
The filing came two weeks after twice-convicted killer Scott Raymond Dozier&aposs lethal injection was postponed for a second time after a lawsuit was filed by New Jersey-based Alvogen opposing the use of its sedative midazolam.
He made his Olympic debut in London as an 18-year-old relay swimmer, sharing in the public shaming after the scandal surrounding the team's recreational use of the sedative Stilnox and watching Magnussen's campaign from close up.
Mr. Ziobro, in his statement on Tuesday, took pains to recite the serious crimes for which Mr. Polanski was convicted, including sex with the 13-year-old, who was under the influence of alcohol and methaqualone, a sedative.
They found that the people who said they used cannabis needed 14 percent more fentanyl, 19.6 percent more midazolam, and 343 percent more propofol during their procedures—higher doses of all three of the commonly used sedative drugs.
Also listed was Salah Tubaigy, whom The Washington Post recently identified as a "medical specialist" for the Saudi Interior Ministry who is said to have administered a powerful sedative to Mr. Khashoggi during a struggle inside the consulate.
When Mr. Ryan asked Dr. Rohrig to describe the effects of quaaludes, which Mr. Cosby has said he has given to women he wanted to have sex with, Dr. Rohrig said the sedative would make the user sleepy.
Stephen Paddock, 64, was prescribed 50 85033-milligram tablets of diazepam, a strong sedative in a drug class called benzodiazepine that has dangerous side-effects, on June 21 by Dr. Steven Winkler, the Las Vegas Review-Journal learned.
The death certificate said that Ms. Hill's death resulted from mixing alcohol with methadone, a medication used to treat opioid use disorder; diazepam and nordiazepam, which have sedative effects; and fluoxetine and norfluoxetine, which are used to treat depression.
The drug, which comes in both liquid and powder forms, has been used in medical settings since the 1970s for pain relief and as a sedative, and it's also being currently studied as a treatment for depression and anxiety.
Alvogen, which said the Nevada Corrections Department had obtained the sedative midazolam unlawfully, won a court order barring the product from being administered to Scott Dozier as part of the state's newly devised and untested three-drug execution protocol.
Nevada had planned to use three drugs in the execution of Scott Dozier, who has been on death row since 2007: one as a sedative, one to paralyze him, and the powerful synthetic opioid fentanyl to help kill him.
In the meantime, lawyers representing death row inmates are trying to stop Arkansas from using the midazolam at all, saying that the drug is an ineffective sedative that leaves an inmate vulnerable to feeling intense pain as they die.
Joel B. Zivot, an associate professor of anesthesiology and surgery at Emory University, said the sedative used in the three-drug cocktail does not inure the inmates to pain and that the paralytic masks the torment they are enduring.
Records obtained by BuzzFeed News show the director of the state corrections department, Wendy Kelly, paid $250 cash for 40 vials of midazolam — a sedative used as the first of three drugs in a lethal injection cocktail — on Aug.
Photo: GettyOwners of very good boys and girls might be perturbed by the latest recall to make the news: 27 brands of dog food pulled from warehouses for possibly containing pentobarbital, a sedative used to euthanize both pets and people alike.
According to a member of the American Association of Zoo Veterinarians quoted by AP, "just a little bit short of a hazmat suit" is used to handle the drug when it's being prepared as a sedative for animals such as elephants.
A Swedish doctor has been charged with rape and kidnapping after he confessed to drugging a woman with sedative-laced strawberries and locking her up in a soundproof bunker where he had intended to keep her for years, prosecutors said Monday.
The documents include admissions by Cosby that he had extramarital affairs, and that he had acquired the sedative known as Quaaludes and engaged in sexual relations with a woman after she took the drug, according to the appeal court's ruling.
Photo: GettyOwners of very good boys and girls might be perturbed by the latest recall to make the news: 27 brands of dog food pulled from warehouses for possibly containing pentobarbital, a sedative used to euthanize both pets and people alike.
Todd McCarthy, The Hollywood Reporter: What ensues is unclear, unfun, indecipherable, indigestible and, before long, an excellent sedative; anyone who could clearly lay out what takes place in this narrative in 25 words or less would deserve a small prize.
Noting that the latter have such a strong sedative effect that they are used as anesthetics, Zibbell said, "More and more people are saying they are using stimulants just to stay awake" rather than seeking the mixed rush of the combination.
Authorities say drug users are also abusing carfentanil, a sedative for large animals, and Hamilton County Coroner Dr. Lakshmi Kode Sammarco said last month that eight deaths in Cincinnati could be attributed to the most potent opioid on the commercial market.
Posted by Julie Schandolph Photography on Thursday, September 1, 2016 Posted by Julie Schandolph Photography on Thursday, September 1, 2016 Steve's doctors suspended his necessary sedative medicine so he could be alert for the wedding, according to Channel 2 Action News.
According to new legal docs obtained by TMZ .... an autopsy revealed Deven had cocaine, heroin, clonazepam (a sedative used to treat seizures or anxiety), topiramate (nerve pain medication) and fluoxetine (used to treat depression) in her system when she died.
Oklahoma: The U.S. Supreme Court cleared Oklahoma to use the controversial sedative midazolam in executions, but due to further legal challenges, ongoing concerns about the state's protocol and its inability to procure the needed drugs, executions have remained on hold.
They will be part of a four-drug combination that also includes the sedative diazepam and the powerful painkiller fentanyl, which has helped fuel the ongoing opioid epidemic in the US. The latter two drugs are not produced by Fresenius Kabi.
The rapid-fire executions, set to begin April 17, were prompted by a looming expiration date on the state's store of the sedative midazolam, one of the pharmaceuticals used in its lethal injection protocol and an increasingly difficult drug to obtain.
Case in point: About 10,63 babies in Germany, Britain, Australia and elsewhere were born with severe defects in the 1950s and '60s after their mothers took thalidomide, a sedative that had been approved by German regulators without testing in pregnant women.
Case in point: About 10,000 babies in Germany, Britain, Australia and elsewhere were born with severe defects in the 1950s and 1960s after their mothers took thalidomide, a sedative that had been approved by German regulators without testing in pregnant women.
The state said it had no plans to change the three-drug sequence that it used in its execution protocol before the moratorium: midazolam, a short-acting sedative; vecuronium bromide, which stops breathing; and potassium chloride, which stops the heart.
Sinaga, who has lived in the United Kingdom since 2007, targeted young men who looked drunk or vulnerable and rendered them unconscious with a sedative, probably the party drug gamma-hydroxybutyric acid that is known as GHB, the court was told.
Many of the last-minute legal moves to postpone the executions have focused not on questions of guilt, but on procedural matters, some surrounding the sedative midazolam, part of a three-drug cocktail that has contributed to botched executions elsewhere.
Critics of midazolam's use in executions say it is a sedative, not an anesthetic, and is thus misapplied as a first round of lethal injection shots, with inmates sometimes able to feel pain from the subsequent lethal drugs that are administered.
"The techs would come in: 'So-and-so is getting me on my nerves watching TV and won't quit talking; come over here and give her a PRN'" — a shot that could contain a sedative such as Ativan or an antipsychotic like Haldol.
Clark County District Court Judge Elizabeth Gonzalez has a September date to begin hearing the pharmaceutical company&aposs allegation that Nevada prison officials illegally obtained midazolam to substitute for expired stocks of another sedative that had been slated for use in November.
According to authorities' account of the kidnapping, Muller was armed with a stun gun and a replica firearm when he crept into the couple's home, ordered them to lie still while he bound and blindfolded them and forced them to drink a sedative.
Riordan, who is not a doctor, said that she had recommended Nuedexta after learning about the medication from a local psychiatrist and had seen it help a number of other aggressive dementia patients without the dangers and sedative effects of an antipsychotic.
While death by electrocution might not sound like it would be less cruel than lethal injection, the constitutionality of the latter method has been called into question in recent years after a series of so-called "botched executions" that used the sedative midazolam.
That protocol – one in which a state employee first injects the prisoner with a sedative rather than anesthesia, then injects a drug that paralyzes the prisoner's body, and finally injects a lethal drug that stops the heart – is inherently and deeply flawed.
William McBride, who was among the first doctors to sound an alarm about thalidomide, the sedative found to cause birth defects, but whose later career was marred by accusations of falsified research results and other misconduct, died on June 241 in Australia.
But if the proposal to ban the sale of fur in New York, legislation put forth by the City Council speaker Corey Johnson, does materialize, it will deliver the fatal sedative to an industry that has moved people forward for so long.
The state's new chief medical officer — who completed an OB-GYN residency but has also trained in epidemiology, according to his government biography — was once again "consulted" about the protocol, which will now include midazolam, a controversial sedative that was deployed in several botched executions.
There are plenty of reasons, though, why doctors and patients would want to avoid using this sedative if possible—not the least of which is that these drugs may have their own stressful side-effects, like trouble breathing or paradoxically becoming more frantic and agitated.
Barr, a Trump appointee who took office in February, effectively brought the litigation back to life with his disclosure that his department had approved a new protocol that calls for using the barbituate sedative pentobarbital for all lethal injections rather than a three-drug combination.
But then something called the rebound effect kicks in: "Once your body has metabolized the alcohol and the sedative effect wears off, you get micro-arousals that disrupt your sleep cycle," Holly Phillips, an internist and the author of The Exhaustion Breakthrough, told VICE.
According to records obtained by the News Service of Florida, Florida's Department of Corrections shelled out more than $12,000 this year on new drugs, one of which is etomidate, a fast-acting anesthetic, which would theoretically replace the sedative Midazolam in lethal injection cocktails.
Radio is an even more intimate medium than premium cable television with a Mature Audiences content rating, and Ms. Cattrall's speech, isolated from other sounds, conjures those sedative tickles of faint euphoria associated with the phenomenon known as A.S.M.R., or autonomous sensory meridian response.
Ketamine is a new depression treatment, but it can also be highly addictiveKetamine, classified as a psychedelic, was originally used as an anesthetic in operating rooms because of its sedative properties and later became a popular-but-illegal party drug for the same reason.
The combination of chemicals — sodium thiopental, a sedative; pancuronium bromide, a paralytic; and potassium chloride, which stops the heart — has been blamed for botched executions and has given rise to lawsuits from death row inmates who said it could subject them to excruciating pain.
These songs share a restrained, mildly sedative quality with recent manifestations of trap and street rap; Metro Boomin and WondaGurl's swaying, loopy beat on "Holding It Down" fits right in with the (largely uncredited) rest — or maybe it's the rest that fits their model.
The medicalization of capital punishment began in 1982 with the first lethal injection in Texas, and for most of the time we've relied on this method, states first injected the condemned with sodium thiopental, a strong barbiturate sedative (in general, barbiturates are stronger than benzodiazepines like midazolam).
Its second season explores what happens after the Process: the moral gray areas within both the Cause and the so-called paradise of the Offshore, the sedative nature of overwhelming privilege, and the often horrific reality behind the stories people tell themselves to sleep at night.
The arguments over drugs Williams and the other seven death row inmates initially fought their executions on the grounds that the sedative Arkansas is using -- midazolam, the drug used to render inmates unconscious in botched executions in other states -- does not reliably prevent a painful death.
His shocking death was ruled suicide by hanging, and a toxicology report later revealed Cornell had several drugs in his system at the time of his death, including butalbital (a sedative), Ativan (lorazepam), pseudoephedrine (a decongestant) and barbiturates in his system at the time of death.
Stoner Superlative: Most likely to get high and decide they should put on more glitter Best Strain: White Widow (creative hybrid) Worst Strain: Death Bubba (sedative indica) Best Way to Get High: High-quality vape cartridges Best High Activity: Make music Recommended Product: Huxton Hifi Cartridge
"Our investigation is one of the first to provide estimates of the suicide risk associated with cannabis, cocaine, amphetamine and sedative use disorders in the same large population, and compare risks associated with these specific substance use disorders between men and women," Bohnert said by email.
As a London cabby from 2002 to 2008, he would show a passenger a satchel full of cash, which he said he had just won at a casino or in a lottery, and urge her to share a celebratory drink that he had spiked with a sedative.
Mr. Moore is scheduled to be executed with a combination of four drugs: the sedative diazepam, commonly known as Valium, to render him unconscious; fentanyl citrate, a powerful synthetic opioid; cisatracurium besylate to induce paralysis and halt his breathing; and potassium chloride to stop his heart.
" And then there's "We Should Be Friends," which provides proof that the old, mischievous Miranda Lambert has not gone very far; that's her, chuckling as she begins the final verse, a salute to people who "use alcohol as a sedative / And 'bless your heart' as a negative.
The episode, at a prison in southeast Arkansas late Thursday, happened in the minutes after the state injected Kenneth D. Williams with a large dose of midazolam, a sedative that has been the subject of legal battles and widespread scrutiny after a series of controversial executions.
Last year, the Supreme Court upheld Oklahoma's use of the drug Midazolam in executions despite claims that it failed to act as enough of a sedative to keep a prisoner from feeling the effects of the other two drugs the state delivers in its lethal injection cocktail.
A murderer named Scott Dozier was expected to become the first inmate executed with a course of drugs including fentanyl in Nevada in July, but a judge halted the execution when one of the makers of the sedative midazolam objected to its use as part of an execution.
Penn may have still been feeling effects of the prescription sleep-aid, Dr. Chris Winter, president of Charlottesville Neurology and Sleep Medicine, told PEOPLE, adding that side effects of the sedative can include "bizarre behaviors or doing things in your sleep that you don't remember," said Dr. Winter.
The sedative effect likely helped calm the boys as they were being hauled through a treacherous maze, but according to the letter from the medics, the drug was also meant to help prevent hypothermia since the boys were carried through cold water while wearing ill-fitting wet suits.
The NBER study concluded that combat exposure not only increases consumption of prescription narcotics and heroin, it also increases sedative and tranquilizer use for non-medical purposes and using opioids together with drugs like benzodiazepines, which also depress the central nervous system and increase the risk of overdose.
Arizona will stop using a controversial sedative linked to botched executions in Oklahoma and Ohio when executing inmates, a lawyer for several prisoners on Arizona's death row announced Monday — part of an agreement that will also see the state open up more of its execution procedures to scrutiny.
Arkansas initially announced that it intended to carry out an unprecedented eight executions in just 19973 days because its supply of midazolam — a controversial sedative that has led to botched lethal injections in states like Arizona, Alabama and Oklahoma — was set to expire at the end of April.
Arkansas initially announced that it intended to carry out an unprecedented eight executions in just 11 days because its supply of midazolam — a controversial sedative that has led to botched lethal injections in states like Arizona, Alabama and Oklahoma — was set to expire at the end of April.
Together with the frustration and the anger from the diagnosis, I had something similar to an epiphany in that same moment: I could see right in front of me the sedative intentions of a capitalist system, hidden under the cover of the economic interests behind certain sectors of the pharmaceutical industry.
The threats to the refugees during crossing have been well documented, but according to a new report published in the Lancet, many of these refugees may have also been exposed to a previously unrecognized danger—the ingestion of gasoline, which is most commonly abused as a sedative in poor communities.
But a urine test revealed that he did have hydrocodone and hydromorphone — two opioid pain medications — and alprazolam, prescribed for anxiety and panic disorders in his system, In addition, there was also zolpidem, a sedative prescribed for insomnia, as well as metabolites of alprazolam and of THC, the active ingredient in marijuana.
Because midazolam is a sedative and not an analgesic, there is a high likelihood that an inmate who receives a high dose of midazolam would be unable to respond to the noxious stimuli that constitute the ADOC's consciousness check, but would still feel the excruciating effects of the second and third drugs.
"But I've talked to people, multiple ones, and they believe that they are putting a slow sedative that they're building up that's also addictive in [Trump's] Diet Cokes and in his iced tea and that the president by six or seven at night is basically slurring his words and is drugged," Jones insisted.
"I guess I would be more inclined to find that [midazolam] was intolerable if there was even some doubt about this drug when there was a perfectly safe other drug available," Justice Antonin Scalia mused during the Glossip oral arguments, referring to a controversial sedative used in two botched executions in Oklahoma.
The four-drug cocktail also includes the sedative diazepam, also known as Valium, and the powerful painkiller fentanyl, which has helped fuel the ongoing opioid epidemic in the US. Amnesty International, one of many groups decrying the execution, said it was the first lethal injection in the United States to include fentanyl.
All the while, the police engaged in a frenetic and televised pursuit, as they tried to corner the animal with a police car (it jumped over the hood) and bring it down with tranquilizer darts (for a time, the bull kept going despite the sedative.) What they really needed was a cowboy.
Viewed through the prism of Adams's novel and the cultural phenomena listed above, rural England is a landscape that feels wild and free—not a bucolic sedative used to placate a nation, but a psychedelic pyre on which to smoke out old ghosts and grievances, to burn up serotonin and ritual bloodlust.
FROM PEN: The Deaths of Carrie Fisher and Debbie Reynolds Hit Hollywood Hard A completed toxicology report for Cornell released earlier this month and obtained by TMZ confirmed that the musician had several drugs in his system at the time of death, including Naloxone (Narcan), Butalbital (a sedative), Lorazepam (Ativan), Pseudoephedrine (a decongestant) and barbiturates.
On Wednesday, Ziegler and Maynard's husband, Dan Diaz, are scheduled to appear at a news conference with lawmakers in Sacramento, California, to announce the introduction of a right-to-die law in the state, similar to the one Maynard relied upon when she took a fatal dose of the sedative secobarbital to end her life.
A federal judge in 2015 released excerpts from a deposition Cosby gave in Constand's civil case in which Cosby acknowledged having obtained Quaaludes, the brand name for a sedative widely abused as a recreational drug in the 1970s, with the intent of giving the pills to young women in order to have sex with them.
Because the sedative – a benzodiazepine known as midazolam – cannot sustain deep unconsciousness the way anesthesia can, it does not prevent the prisoner from experiencing either the feeling of suffocation that the second, paralyzing, drug inflicts, or the feeling of liquid fire that follows the large and fatal dose of the third heart-stopping drug.
The file was nowhere to be found at the scene of her death, and other evidence renders the cause of her death inconclusive; marks on her car suggested she may have been driven off the road by someone but the coroner also found nearly twice the recommended dosage of the sedative Quaalude in her blood.
The Eighth Amendment prohibition against "cruel and unusual" punishment served as a measure of the elastic morality that facilitates the death penalty: does it constitute cruelty to infuse the condemned with a sedative, rather than a stronger anesthetic, particularly if, as attorneys for Jones and Williams argued, the circulatory conditions of the men might impair its effectiveness?
This agreement will help settle a lawsuit first brought by a group of death row inmates in 2014 — the same year Arizona officials brutally botched the execution of Joseph Wood, a convicted murderer who took nearly two hours to die, reportedly gasping throughout even as officials pumped him with 15 times the standard dose of the sedative midazolam.
Per the Associated Press, Alvogen claimed that Nevada prison officials obtained the sedative, which authorities have used in numerous botched executions that left prisoners in extreme pain, via "subterfuge":State prisons spokeswoman Brooke Santina announced the decision Wednesday afternoon after a state court judge in Las Vegas earlier in the day ordered the delay at the request of New Jersey-based drugmaker Alvogen.
In a study published in December in the Journal of Medicinal Food, researchers from Sahmyook University in Seoul, South Korea dosed a group of mice and rats with night milk, and found that the effects of the night milk on the rodents was comparable to the effects of diazepam (first marketed as Valium), a drug known for its sedative effects.
TENNESSEE CONVICTED CHILD KILLER BILLY RAY IRICK PICKS DELUX BURGER COMBO AS LAST MEAL BEFORE EXECUTION Moore is scheduled to be executed with a combination of four drugs: the sedative diazepam, commonly known as Valium, to render him unconscious; fentanyl citrate, a powerful synthetic opioid; cisatracurium besylate to induce paralysis and halt his breathing; and potassium chloride to stop his heart.
"If the midazolam fails to keep the prisoner under anesthesia, the prisoner would be awake and aware but unable to move or speak or even open his eyes, so he would then look completely serene despite being in agony," Braden said, adding that forcing Williams to experience such pain without a sedative would be a violation of the Eighth Amendment, which outlaws cruel and unusual punishment.
Sergeant: Inmate told me she just wanted to sleep According to interview notes, the sergeant, who retired this year after more than 22 years of service, told an investigator that Coltrain used the jail phone at her booking, made a call that got her upset, and then admitted to him that she had a dependency on benzodiazepines, a class of medication with sedative properties.

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