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"nonfunctioning" Definitions
  1. not performing or able to perform a function : not functioning : NONFUNCTIONAL
  2. [medical] not secreting hormones or not secreting hormones that produce clinical symptoms

78 Sentences With "nonfunctioning"

How to use nonfunctioning in a sentence? Find typical usage patterns (collocations)/phrases/context for "nonfunctioning" and check conjugation/comparative form for "nonfunctioning". Mastering all the usages of "nonfunctioning" from sentence examples published by news publications.

The caller gave a nonfunctioning email address at the paper.
Officers try to direct drivers amid massive traffic snarls caused by nonfunctioning signals.
Those include items like missing track fasteners, defective rail ties and nonfunctioning lightbulbs in tunnels.
Drivers in the area had to be careful for the debris, floodwater, and nonfunctioning traffic lights.
They have a condition where their uterus is either nonfunctioning or nonexistent called absolute uterine factor infertility.
When I asked about the nonfunctioning website, Mr. Harr told me the business was on hiatus, seeking funds.
The living room contains the original (currently nonfunctioning) stone fireplace, painted white and flanked by built-in bookshelves.
One of three functioning fireplaces (there are also two nonfunctioning ones) is near the base of the grand staircase.
Mr. Lafergola's lawyer, Evan F. Nappen, described him as a "hobbyist" who built the weapons as "nonfunctioning models" from kits.
After being moved to a room the next morning, I needed to consult a stoma nurse about my nonfunctioning ileostomy.
As noted above there's a (potentially nonfunctioning) option to generate an address to receive bitcoin, but no option to send it.
Large numbers of Vietnamese babies continue to be born with grotesque deformities: misshapen heads, bulging tumors, underdeveloped brains and nonfunctioning limbs.
And if you think these nonfunctioning earbuds are some kind of elaborate joke, you clearly aren't familiar with the ASOS brand.
Women who participate in the trial have what's called absolute uterine factor infertility (AUI), which means their uterus is nonfunctioning or nonexistent.
Emerge from cuffing season victorious and self-improved while everyone around you crumbles into a nonfunctioning puddle of emotional drama and UTIs.
The same patterns showed up again: Local commanders had warned higher-ups of a lack of training, nonfunctioning aircraft and faulty equipment.
Taking design inspiration from a yacht, the Skiff has a center door along the side and even a nonfunctioning propeller in the back.
While the extremity was nonfunctioning, it still caused Griffin great pain, to the point he even considered removing it himself as a child.
In the cab, police found an automatic 7.65-millimeter pistol, two fake assault rifles, a nonfunctioning grenade, and a cellphone and unspecified documents.
"If you let the idea of making a moral decision infect your life to that level, you become a nonfunctioning human being," he adds.
But it was estimated that it would cost $1 million to dismantle the nonfunctioning mechanisms, so city officials decided to keep them in place.
Hydzik said Haines was very sick when admitted into Shadyside with leukemia and a nonfunctioning immune system, and was immediately put on anti-fungal treatment.
At the same time, the newly elected Parliament remains in a nonfunctioning deadlock just days into its term over the vote for a new speaker.
They also found a fake automatic pistol; two fake assault rifles, a Kalashnikov and an M-16; a nonfunctioning grenade; and a mobile phone and documents.
"We are sorry to inform you about some unfortunate news," CEO Nolan Mondrow wrote in an email to those unfortunate enough to be stuck with a nonfunctioning LS-6i.
"This single channel, when it is nonfunctioning in a human being, renders them unable to understand or feel any form of pain," Sherrington says, summarizing the team's initial findings.
Lorraine Sperling said at the meeting that neighboring Airbnb guests once tried to operate a nonfunctioning fireplace and accidentally caused a gas leak in the middle of the night.
The Neon Museum in Las Vegas, devoted to castoff signage from around the Las Vegas Strip, recently introduced Brilliant, a sound and light show that animates the nonfunctioning signs.
This colleague has always been a heavy drinker and has alcoholism in his family; I now wonder if he is transitioning from being a functioning alcoholic to a nonfunctioning one.
It's a real-ish building inside, with a (nonfunctioning) bathroom, snack fridges, purpose-built metal computer terminals, an ornate inlaid table meant to be a high-tech scanner, and so on.
Conventional estimates of the cost of the shutdown are almost surely too low, because they don't take account of the disruption a nonfunctioning government will impose on every aspect of life.
Many voters also suffered other voting issues such as long lines and broken or nonfunctioning voting machines, but the president demurred when he was asked if he was concerned about those difficulties.
"Many are unaware of the increased risk, but more importantly removal of nonfunctioning leads requires special skills that a majority of device implanters do not have, and specialized equipment as well," Wilber said by email.
Founded in 2016 by Paul Gondry, 27, whose father is the film director Michel Gondry, and the artist Shelby Jackson, 28, 15 Orient's living-room gallery has a nonfunctioning fireplace and a large bay window.
In February, when Mayre Dickson, an artist in New Mexico, received an orange 2012 Furby in the mail from an online seller, his battery compartment was flooded with battery acid and he was completely nonfunctioning.
It's true that Democrats had a lot to lose, but Republicans had even more; if Trump had to deliver his State of the Union to a nonfunctioning government, it would have underlined the sense that he's a chaos president.
For years facilities have been providing patients with spaces that hark back to their younger years — perhaps a faux office with a roll top desk and dial phone or a nonfunctioning kitchen with wooden spoons and an ironing board.
" The article stated that "The effects of such limited overhead investment are felt far beyond the office: nonfunctioning computers cannot track program outcomes and show what is working and what is not; poorly trained staff cannot deliver quality services to beneficiaries.
After a 12-day period during which the filters were removed, the researchers did another nine-day test: the students in the original functioning-filter group got non-working filters, and those in the original nonfunctioning-filter group got filters that worked.
On the hate side: the prose can be extremely clumsy, as it is in this paragraph where teenage protagonist Wade Watts describes the virtual car he constructed for himself in the vast online world where he spends most of his waking hours: The DeLorean came outfitted with a (nonfunctioning) flux capacitor, but I'd made several additions to its equipment and appearance.
Nonfunctioning pancreatic tumors also occur in patients with MEN 1 and may be the most common type of pancreatoduodenal tumor in MEN 1. The size of the nonfunctioning tumor correlates with risk of metastasis and death.
Like other members of the Ariidae, hardhead catfish are paternal mouthbrooders. After spawning, the male carries the eggs in his mouth until they hatch. Several nonfunctioning eggs within the brood attach to the larger, viable eggs. These nonfunctioning eggs may be used as food for the male mouthbrooder, since mouthbrooders do not feed while they are taking care of the brood.
Early graft failure is probably due to preexisting disease of the donated organ. Others include technical flaws during surgery such as revascularization that may lead to a nonfunctioning graft.
Turnersburg Township is a nonfunctioning administrative division in northeastern Iredell County, North Carolina, United States. Turnersburg township was established in 1868. The only major town in Turnersburg township is Harmony, which is also partially within Eagle Mills township.
Rowland Township is a nonfunctioning township in Robeson County, North Carolina, United States. The United States Census Bureau's 5-year estimate (2011-2015) for the "civilian employed population 16 years and over" is 1018 +/-142. It contains the town of Rowland.
James Edward Holly confessed to investigators that he made the calls with two "nonfunctioning" phones because he was angry with Horton. Ross, who was shot multiple times in the chest and arm, was injured, but was treated for his injuries and released from a local hospital.
The first antennae (antennules) are small, slender filaments on the ventral surface of the head, at about the same level as the eyes. The second antennae are similar and lie laterally to the first. They are nonfunctioning. The large, well-developed mandibles oppose each other across the ventral midline.
Front entrances are sheltered by porches or stoops. All of the one- story, one-bay porches feature hipped, shed or gable roofs supported by wooden Tuscan or Doric columns, square or turned wooden posts or brick piers. Front entrance stoops often are sheltered by bracketed canopies. Many buildings have nonfunctioning brick chimneys.
Clinically euthyroid patients do not have elevated thyroid-stimulating hormone (TSH) levels. Pathogenesis is unknown but may include decreased peripheral conversion of T4 to T3, decreased clearance of rT3 generated from T4, and decreased binding of thyroid hormones to thyroxine-binding globulin (TBG). Examples of a nonfunctioning thyroid gland may be hypothyroidism, hyperthyroidism, or thyroiditis.Definition of Euthyroid, MedicineNet.
"Dhakki" is one of the famous and delicious amongst all dates and is a major part of export. The famous nearby picnic spots are TOY (a natural water resort and play ground) and the mountainous hilly region of Sheikh Badin that comprises lush green forest, an old nonfunctioning post office and police station of British time.
A nonfunctioning centriole lies adjacent to the kinetosome. Nine interconnected props attach the kinetosome to the plasmalemma, and a terminal plate is present in the transitional zone. An inner ring-like structure attached to the tubules of the flagellar doublets within the transitional zone has been observed in transverse section. No roots associated with the kinetosome have been observed.
They are located on chromosome 11p. Expression of the h19 gene is markedly reduced in both nonfunctioning and functioning adrenal cortical carcinomas, especially in tumors producing cortisol and aldosterone. Also, a loss occurs of activity of the p57kip2 gene product in virilizing adenomas and adrenal cortical carcinomas. In contrast, IGF-II gene expression has been shown to be high in adrenal cortical carcinomas.
Bronchopulmonary sequestration (BPS) is a rare congenital malformation of the lower respiratory tract. It consists of a nonfunctioning mass of normal lung tissue that lacks normal communication with the tracheobronchial tree, and that receives its arterial blood supply from the systemic circulation. BPS is estimated to comprise one to six percent of all congenital pulmonary malformations, making it an extremely rare disorder. Sequestrations are classified anatomically.
They feature Chevrolet small-block engines, recolored interiors, custom seats, and nonfunctioning radios. Other than the one used in the original, all of the Impalas had to be painted black for the series. One of the Impalas used features a detachable roof and doors for up-close shots, and is capable of being separated in half. After filming of the series concluded, Ackles was allowed by Warner Bros.
M. acridum only targets and affects grasshoppers and locusts. Researchers believe that this has to do with the Mest1 gene which is not present in M. acridum. By taking a strain of M. robertsii that has a nonfunctioning Mest1 gene, researchers found that the mutant was only able to infect grasshoppers and locusts which is consistent with M. acridum. This allows the initiation of the infection process on the specific targets.
Each cluster has up to three bisexual flowers and up to seven male flowers with nonfunctioning female parts. The flowers have purple petals, making it easy to identify among the sanicles present in Hawaii. This plant grows in boggy habitat among other plants such as Argyroxiphium grayanum and Oreobolus furcatus. By 1996 there was only one population remaining on Oahu, and possibly another, but the latter had not been seen in years.
Lethal white syndrome, or ileocolonic aganglionosis, will result in meconium impaction since the foal does not have adequate nerve innervation to the large intestine, in essence, a nonfunctioning colon. Foals that are homozygous for the frame overo gene, often seen in Paint horse heritage, will develop the condition. They present with signs of colic within the first 12 hours after birth, and die within 48 hours due to constipation. This syndrome is not treatable.
Pseudogenes are vestiges of once-functional genes disabled by sequence deletions, insertions, or mutations. The primary evidence for this process is the presence of fully functioning orthologues to these inactivated sequences in other related genomes. Pseudogenes commonly emerge following a gene duplication or polyploidization event. With two functional copies of a gene, there is no selective pressure to maintain expressibility of both, leaving one free to accumulate mutations as a nonfunctioning pseudogene.
Injuries are often the cause of aphonia . Minor injuries can affect the second and third dorsal area in such a manner that the lymph patches concerned with coordination become either atrophic or relatively nonfunctioning. Tracheotomy can also cause aphonia. Any injury or condition that prevents the vocal cords, the paired bands of muscle tissue positioned over the trachea, from coming together and vibrating will have the potential to make a person unable to speak.
While the webcast video ended prematurely, SpaceX was able to retrieve telemetry for the entire flight. The status of the first stage is unknown; it was not recovered because of problems with a nonfunctioning GPS tracking device. The rocket reached a final altitude of and a final velocity of 5.1 km/s, compared to 7.5 km/s needed for orbit. SpaceX characterized the test flight as a success, having flight-proven over 95% of Falcon 1's systems.
Problems of the thyroid gland occur in 20–50% of individuals with Down syndrome. Low thyroid is the most common form, occurring in almost half of all individuals. Thyroid problems can be due to a poorly or nonfunctioning thyroid at birth (known as congenital hypothyroidism) which occurs in 1% or can develop later due to an attack on the thyroid by the immune system resulting in Graves' disease or autoimmune hypothyroidism. Type 1 diabetes mellitus is also more common.
In January 2014 Vectrix ceased all US operations. After numerous manufacturing problems resulting in failed batteries and nonfunctioning scooters, Vectrix's parent company Gold Peak, a Chinese battery manufacturer, decided to close down Vectrix's US facilities. Vectrix intended to maintain its Poland fabrication plant in order to continue to supply parts for its joint venture with Daimler's Smart division. In March 2014 Vectrix filed for bankruptcy again, this time under Chapter 7 for liquidation of the company.
In Cohen syndrome, it is thought that deletion mutations in the gene alter the shape of the VPS13B protein, resulting in a shorter, nonfunctioning protein. Altered VPS13B protein is then unable to function properly due to these genetic changes, thus resulting in an obstruction of regular processes. Studies have also linked mutations in the VPS13B gene to osteoporosis. An association between an increase of the VPS13B copy number variants and a lower bone mineral density in adults has been found.
Redox dysregulation leads to increases in nitrosative stress in the endoplasmic reticulum. Such adverse changes in the normal cellular environment of susceptible cells, such as neurons, leads to nonfunctioning thiol-containing enzymes. More specifically, protein disulfide- isomerase can no longer fix misfolded proteins once its thiol group in its active site has a nitric monoxide group attached to it; as a result, accumulation of misfolded proteins occurs in neurons, which has been associated with the development of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
Lethal white syndrome (LWS), also called overo lethal white syndrome (OLWS), lethal white overo (LWO), and overo lethal white foal syndrome (OLWFS), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11-month gestation and externally appear normal, though they have all-white or nearly all-white coats and blue eyes. However, internally, these foals have a nonfunctioning colon. Within a few hours, signs of colic appear; affected foals die within a few days.
The Analyst Newspaper, Liberia : AFL Regaining Shape, September 2007 (Nonfunctioning link removed). The Minister of Defense that President Ellen Johnson Sirleaf appointed in early 2006, Brownie Samukai, had a good public reputation.IRIN, LIBERIA: Sirleaf unveils first members of new peacetime government , January 17, 2006 A U.S. Marine Corps officer speaks to AFL troops during a 2009 training exercise. There appears to be some lack of coordination, at least according to The Wall Street Journal, between the Ministry of National Defense and DynCorp, who is training the new army.
NETs can start in most organs of the body, including the pancreas, where the various malignant types are all considered to be rare. PanNETs are grouped into 'functioning' and 'nonfunctioning' types, depending on the degree to which they produce hormones. The functioning types secrete hormones such as insulin, gastrin, and glucagon into the bloodstream, often in large quantities, giving rise to serious symptoms such as low blood sugar, but also favoring relatively early detection. The most common functioning PanNETs are insulinomas and gastrinomas, named after the hormones they secrete.
Type I Gaucher's disease is an autosomal recessive disorder; parents are generally healthy carriers with one functional and one mutated (nonfunctioning) copy of the Gaucher disease gene, GBA. People with type I Gaucher have a defect in the enzyme called glucocerebrosidase (also known as acid β-glucosidase). Glucocerebrosidase is an enzyme, and its function is to convert glucocerebroside (also known as glucosylceramide) into ceramide and glucose. When this enzyme doesn't work, glucocerebroside accumulates, which in turn causes liver and spleen enlargement, changes in the bone marrow and blood, and bone disease.
Her lab's methods involve using a gel to deliver drugs to a specific location in the central nervous system and to bypass the blood-brain barrier. The drugs delivered in this way include chemotherapy drugs and agents to slow or reverse damage from a stroke. This delivery method is also being tested with stem cells, and include studies on the use of hydrogels that deliver stem cells to nonfunctioning retinas. These hydrogels are designed to be easily injectable into the tissue and they then form a scaffold for cells to grow in the appropriate three-dimensional shape.
The BNSA was provisionally suspended for "Non-adherence to the Constitution of the Organization and nonfunctioning as a democratic National Scout Movement" in 2002, after "Complaints (...) received from unrecognised groups within the country about the conduct of the recognised NSO", which led to a report by WOSM's Chairman of the Constitutions Committee, demanding a legitimate general assembly and an independent auditing of its accounts. There was also an earlier provisional suspension for non-payment of membership fees. The Scout Motto is Bud' Gotov, Be Prepared in Russian, as BNSA does not use the Belarusian language, Russian is the sole official language. The name of the organisation in Belarusian is ().
The fountain of Piazzale dei Partigiani immortalized in the final scene of Carlo Verdone's Un sacco bello in 1980. The square outside of the station was named Piazzale dei Partigiani after World War II. Now, the square's primary function is a bus terminal and parking facility. Before 1990, however, the piazza was embellished with a well-maintained garden and a now- nonfunctioning fountain that was built in the 1950s as part of the design of the station's architect Roberto Narducci. The fountain was inexplicably excluded from the modernization and renovations for the 1990 World Cup, even though the square was part of the ambitious "Cento Piazze" beautification project.
A 2007 study by CELS and international NGO Mental Disability Rights International reported that 25,000 persons were detained in psychiatric institutions, more than 80 percent for more than a year. The report documented egregious cases of abuse and neglect in psychiatric institutions, including patients burned to death in isolation cells, the use of sensory deprivation in long-term isolation, and physical and sexual violence. The report also detailed dangerous and unhygienic conditions, including the lack of running water, nonfunctioning sewer systems, and fire and safety hazards. The National Advisory Committee for the Integration of People with Disabilities, under the National Council for Coordination of Social Policies, has formal responsibility for actions to accommodate persons with disabilities.
If primary hyperaldosteronism is confirmed biochemically, CT scanning or other cross-sectional imaging can confirm the presence of an adrenal abnormality, possibly an adrenal cortical adenoma (aldosteronoma), adrenal carcinoma, bilateral adrenal hyperplasia, or other less common changes. Imaging findings may ultimately lead to other necessary diagnostic studies, such as adrenal venous sampling, to clarify the cause. It is not uncommon for adults to have bilateral sources of aldosterone hypersecretion in the presence of a nonfunctioning adrenal cortical adenoma, making adrenal venous sampling mandatory in cases where surgery is being considered. The diagnosis is best accomplished by an appropriately-trained subspecialist, though primary care providers are critical in recognizing clinical features of primary aldosteronism and obtaining the first blood tests for case detection.
SP-B and SP-C are the two hydrophobic surfactant proteins that participate in its physical functions; these proteins are encoded by SFTPB and SFTPC genes on chromosomes 2 and 8 respectively. Thus, mutations on these genes produce incomplete or nonfunctioning SP-B and SP-C proteins and lead to lung diseases. Both SP-B and SP-C are synthesized in epithelial type II cells as large precursor proteins (proSP-B and proSP-C) and subsequently cleaved by proteolytic enzymes at both amino and carboxyl termini to produce functional mature proteins. proSP-B and proSP-C are first made in the endoplasmic reticulum of epithelial type II cell, they are then translocated through Golgi apparatus to multivesicular bodies for delivery to lamellar bodies.
Many eminent country music artists, such as Jimmie Rodgers, Loretta Lynn, Patsy Cline, Ernest Tubb, Johnny Horton and Merle Haggard, began their careers as amateur musicians in honky-tonks. The modern-day honky-tonk atmosphere has continued with the likes of Dwight Yoakam, Turnpike Troubadours, and Mike and the Moonpies. The origin of the term honky-tonk is disputed, originally referring to bawdy variety shows in areas of the old West (Oklahoma, the Indian Territories and Texas) and to the actual theaters showing them. The first music genre to be commonly known as honky-tonk was a style of piano playing related to ragtime but emphasizing rhythm more than melody or harmony; the style evolved in response to an environment in which pianos were often poorly cared for, tending to be out of tune and having some nonfunctioning keys.
One month before their transfer, when Wright had still been at Maghaberry, they had organised an unsuccessful hostage-taking incident at the prison. This was meant to end in the assassination of Wright; he was subsequently moved to the Maze. Other questions were raised after the discovery that on the morning of the killing, Prison Officer Raymond Hill was stood down from his post in the watchtower overlooking A and B wings of H-Block 6 where the INLA prisoners were housed. The CCTV camera placed in the area was also found to have been nonfunctioning for several days prior to the shooting. The visitors lists for 27 December 1997 had been circulated in both the LVF and INLA wings the day before thereby giving Wright's assassins time to prepare for the killing as the list clearly stated that Wright was scheduled to receive a visit on 27 December.
50px This article contains quotations from this source, which is available under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. but genetic changes that made it highly virulent did not occur until about 4,000 years ago. 50px This article contains quotations from this source, which is available under the Creative Commons Attribution 4.0 International (CC BY 4.0) license. The highly virulent version capable of transmission by fleas through rodents, humans, and other mammals was found in two individuals associated with the Srubnaya culture from the Samara region in Russia from around 3,800 years ago and an Iron Age individual from Kapan, Armenia from around 2,900 years ago. This indicates that at least two lineages of Y. pestis were circulating during the Bronze Age in Eurasia. The Y. pestis bacterium has a relatively large number of nonfunctioning genes and three "ungainly" plasmids, suggesting an origin less than 20,000 years ago.
World War II in Europe began on September 1, 1939, with Germany's invasion of Poland, and two days later Britain and France declared war on Germany, so it was a surprise when representatives of the two western powers showed up at a special commission session in neutral Romania in February 1940; the British and French representatives were greeted with "hearty handshakes" by the German delegate, whose turn it was to preside. "Although the conference was behind closed doors," the New York Times reported, "it was believed that the principal subject of discussion was liquidation of the commission."New York Times, February 17, 1940 In August 1940, the Reich unilaterally announced the dissolution of the European Commission, noting that Germany and Italy had withdrawn and Britain and France were nonfunctioning members. "German quarters noted with satisfaction that this ends the existence of a valuable source of information for the Allies on the economic situation in Danubian territory," reported the New York Times.New York Times, August 30, 1940 Meanwhile, the upstream International Danube Commission was undergoing similar Nazi-imposed changes.

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