The bone microstructure, or histology, of extinct vertebrates gives a unique view on how they lived.
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Bone histology, or the study of the microscopic structure of tissues within the bones, revealed this detail, according to the report.
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Cardiac pathology, neuropathology, toxicology and histology testing are still necessary to determine the cause of death, according to the Medical Examiners Office.
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It uses an optical imaging technique called stimulated Raman histology (SRH) to create images that the AI algorithm assesses in less than 150 seconds.
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The key to the study was the use of lasers to scan tissue samples with certain wavelengths of light, a technique called stimulated Raman histology.
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A 35-millimeter film scanner whirred through black-and-white negatives in October, as Schmidt sat in a histology lab, inspecting a box full of swabs.
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For more, click on * Novartis said it had first-of-its-kind histology data with iscalimab (CFZ533) suggesting the extended survival of transplanted organs may be possible.
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The researchers said that histology, or cutting up the bones, was the only way for them to truly know the life stage of the dinosaurs when they died.
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The Cook County Medical Examiner's Office tells PEOPLE that the musician's cause of death has officially been deferred pending additional studies, including cardiac pathology, neuropathology, toxicology and histology.
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The Cook County Medical Examiner's Office tells PEOPLE that the "Lucid Dreams" musician's cause of death has officially been deferred pending additional studies, including cardiac pathology, neuropathology, toxicology and histology.
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The agency runs offices in every borough, three mortuaries and the country's largest public DNA lab, along with other labs for toxicology, molecular genetics and histology, the microscopic examination of tissue.
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Lorna Steel, a curator in the Earth Sciences Department at the National History Museum in London who specializes in bone histology, crocodylomorpha, fossil reptile curation, and pterosauria, is now my favorite person.
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"Because of the histology, or what it looked like under the microscope was a rather low-grade tumor, I thought we had a good chance of helping her," he told the news outlet.
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For more, click on Roche said it received clearance from the U.S. Food and Drug Administration (FDA) for its CINtec Histology test that should help improve consistency in the diagnosis of cervical pre-cancers.
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The Cook County Medical Examiner's Office announced in a statement Monday that additional studies -- including toxicology, histology, cardiac pathology and neuropathology tests -- are required to establish the cause and manner of death of the recording artist.
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"It feels not too long ago that I was on my college campus just sitting around with my friends in the food court playing 'League of Legends' between our next classes," said Kristin Milicich, 32, a histology technician.
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The researchers used two techniques to study the bones of the baby dino: bone histology (in other words, a microscopic-level look at the bone cells) and X-ray computed tomography (essentially a run-of-the-mill CT scan).
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I can't get life insurance, I couldn't get travel insurance, I can't drive for a year, and I couldn't give blood until my histology results came back I was supposed to be out of work for 12 weeks, but I was back after six.
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Although one may divide microscopic anatomy into organology, the study of organs, histology, the study of tissues, and cytology, the study of cells, modern usage places these topics under the field of histology. In medicine, histopathology is the branch of histology that includes the microscopic identification and study of diseased tissue. In the field of paleontology, the term paleohistology refers to the histology of fossil organisms.
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Fawcett is the author of The Cell, a classic cell biology text, and was author of several editions of Bloom and Fawcett: A Textbook of Histology, the definitive histology textbook to generations of students.Fawcett D. W (1997) Bloom and Fawcett: a textbook of histology. 12th Sub edition. London: A Hodder Arnold Publication.
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Wheater's Functional Histology, 5th ed. Young, Lowe, Stevens and Heath.
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1 In histology, potassium permanganate was used as a bleaching agent.
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Stacey E. Mills — Histology for Pathologists: 3rd (third) Edition, page 670.
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Ross M, Pawlina W. Histology. 5th ed. Baltimore, MD: Lippincott Wiliams & Wilkins; 2006.
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Basic Histology. Lake house Investments and Publishers Ltd., Colombo, Sri Lanka. 171 pp.
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The structure and function of the epididymis I. The histology of the rat epididymis. Australian Journal of Zoology 5: 223-246.Nicander, L. & Glover, T. (1973). Regional histology and fine structure of the epididymal duct in the golden hamster (Mesocricetus auratus).
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One of the major applications for CRS is label-free histology, which is also called coherent Raman histology, or sometimes stimulated Raman histology. In CRH, CRS images are obtained at lipid and protein images and after some image processing, a image similar to H&E; staining can be obtained. Different from H&E; staining, CRH can be done on live and fresh tissue and doesn't need fixation or staining.
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Dogiel studied at Kazan University where he graduated in 1883. He inaugurated his career in 1885 as a monitor in embryology. Then he taught and practiced histology, first in Tomsk from 1888, then in 1892 at the Saint Petersburg Medical Institute where he was entrusted with the organization of the histology laboratory. He founded the Russian Archives of Anatomy, Histology and Embryology (Рус, архив анатомии, Gistology and Embryology).
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Alongside Magyarosaurus, Telmatosaurus and Zalmoxes also are dwarfed genera, as proven by their histology.
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He worked with Alexander A. Maximow and William Bloom on their Textbook of Histology.
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Human Anatomy, Embryology, and Histology 2\. Biochemistry and Physiology 3\. Microbiology and Pathology 4\.
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Later she became a Professor Emeritus, known for her teaching of histology, embryology and cytology.
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Gartner, L.P. & Hiatt, J.L. 2000. Color Atlas of Histology, 3rd Edition. Lippincott Williams & Wilkins, Philadelphia.
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Pictogram of margin controlled histology or CCPDMA Pictogram of standard bread loafing histology False negative in standard bread loafing histologyBread loafing is a common method of processing surgical specimens for histopathology. The process involves cutting the specimen into 3 or more sections.Fong, Kenneth., Malhotra, Raman.
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The field of histology that includes the preparation of tissues for microscopic examination is known as histotechnology. Job titles for the trained personnel who prepare histological specimens for examination are numerous and include histotechnicians, histotechnologists, histology technicians and technologists, medical laboratory technicians, and biomedical scientists.
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The histological subtype and the patient's age and health status also help predict prognosis. The epithelioid histology responds better to treatment and has a survival advantage over sarcomatoid histology. The effectiveness of radiotherapy compared to chemotherapy or surgery for malignant pleural mesothelioma is not known.
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Histology of the Larval Neodiprion abietis (Hymenoptera: Diprionidae) Digestive Tract. Journal of Entomology. 2012: 1-10.
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Levenson, R. (2017). Microscopy with ultraviolet surface excitation for rapid slide-free histology. Nature Biomedical Engineering. doi:10.1038/s41551-017-0165-y.Richard M. Levenson, Zachary Harmany, Stavros G. Demos, Farzad Fereidouni, "Slide-free histology via MUSE: UV surface excitation microscopy for imaging unsectioned tissue (Conference Presentation)", Proc.
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Reinke crystals are rod-like cytoplasmic inclusions which can be found in Leydig cells of the testes.Young, Barbara; Woodford, Phillip; O'Dowd, Geraldine (2013-10-09). Wheater's Functional Histology: A Text and Colour Atlas (FUNCTIONAL HISTOLOGY (WHEATER'S)) (Kindle Locations 9938-9939). Elsevier Health Sciences UK. Kindle Edition.
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3Scan’s technology changes the histology workflow to automate the process of tissue sectioning and imaging. Traditionally, histology slides are prepared by embedding a tissue sample in paraffin, taking some few slices of the tissue with a hand-driven microtome, mounting the tissue slices on slides, and staining with various histology stains. A pathologist then looks at these slides with a microscope. In the workflow developed by 3Scan, tissues are stained, embedded, and then sliced and imaged by the KESM.
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Ten Cate's Oral Histology: Development, Structure, and Function. 7th ed. St. Louis, MO: Mosby Elsevier, 2008. Print.
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Edwin John Quekett FRMS (1808–1847) was an early worker in botany and histology, and a microscopist.
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In histology, a lacuna is a small space containing an osteocyte in bone or chondrocyte in cartilage.
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Trauth's research concerns conservation, microscopic anatomy, histology, reproductive biology parasitology, natural history, and behavior of amphibians and reptiles.
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He also serves as the editor of the Histology section of the Journal of Anatomical Society of India.
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This section discusses the tumorigenesis of neurofibroma in terms of genetics, cell signaling, histology and the cell cycle.
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Bone histology of the non-avian dinosaur Shuvuuia and the early bird Confuciusornis The use of histology in paleontology has traditionally been more focused on examining long bones such as the femur or the humerus. Previous work on long bone histology revealed differences in the growth patterns of polar dinosaurs, identified a case of dwarfism in Europasaurus, reconstructed the life history of Dysalotosaurus by examining multiple specimens of different ontogenetic stages, and suggested that Psittacosaurus underwent a postural change from a quadruped to biped as it matured. By contrast, dental histology has not been looked at in great detail in dinosaurs until more recently and there has been an increase in interest in this particular sub-field. Histology studies traditionally rely upon the destructive process of creating and examining thin sections under microscopy, often restricting studies to taxa that have plentiful specimens such as isolated teeth or damaged specimens.
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According to the Eolas Web site, their current products include two health-education systems: the AnatLab Visible Human, used to teach gross anatomy to medical students, and AnatLab Histology, an iOS and Android app that provides mobile access to a complete collection of ultra-high-resolution histology microscopic slide images.
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Vialleton was born in Vienne. He was the first professor of histology in the faculty of medicine at the University of Montpellier.Lavabre-Bertrand T. (2015). Louis Vialleton (1859-1929) was the first Professor of Histology in the Faculty of medicine of Montpellier. Rev Hist Pharm (Paris) 62 (385): 109-123.
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Diagnosis is generally made by endoscopy with biopsy to evaluate histology. Review of symptoms and associated conditions is important.
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Red 2G can be also used for staining in histology, though rarely, e.g. as a component of Masson's trichrome.
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Platypus by Ann Moyal, pages 160-166 In 1921 was made the first Chair of Embryology and Histology at UCL.
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Some complementing stains used alongside Bismark brown are Hematoxylin and Toluidine blue which provide better contrast within the histology sample.
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The histology of Magyarosaurus showed that it had a very reduced growth rate, but even so, had a high metabolic rate.
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In turn, euconodont and paraconodont elements are more similar, in terms of histology and histogeny, than either is to protoconodont elements.
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Micrograph of chorionic villi with Hofbauer cells. H&E; stain. Under histology sections, Hofbauer cells have appeared with discernible amount of cytoplasm.
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Toluidine blue, also known as TBO or tolonium chloride (INN) is a blue cationic (basic) dye used in histology and sometimes clinically.
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As in the descending limb, the epithelium is simple squamous epithelium.Pawlina, Wojciech and Ross, Michael. Histology: A text and Atlas. 5th ed.
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Ross, M. H. and Pawlina, W. (2011) Histology, 6th ed., Lippincott Williams & Wilkins, p. 218. Type I collagen gives bone its tensile strength.
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With the great scientific and technical advances of the time, the museum began to acquire anaesthetic equipment, histology slides, X-rays and photographs.
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In some kinds of lung cancer (with squamous-cell histology) sorafenib administered in addition to paclitaxel and carboplatin may be detrimental to patients.
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The diagnosis of synovial sarcoma is typically made based on histology and is confirmed by the presence of t(X;18) chromosomal translocation.
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Afternoon sessions consist of a theory class followed by laboratory work in Physiology or Biochemistry or it may be histology branch of anatomy.
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Notheia conceptacles. Photo taken from an embedded wax block during histology studies. Notheia produces male and female gametangia in the same conceptacle (monoecious).
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Histologic specimen being placed on the stage of a light microscope. Human lung tissue stained with hematoxylin and eosin as seen under a microscope. Histology, also known as microscopic anatomy or microanatomy, is the branch of biology which studies the microscopic anatomy of biological tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures visible without a microscope.
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His predecessor's practical course had been limited to microscopic histology. Stirling introduced demonstrations of experimental physiology. Stirling was, upon the resignation of Arthur Gamgee, appointed the Brackenbury Professor of Physiology and Histology at Owens College (in 1904 renamed the Victoria University of Manchester) from 1886 until his retirement in 1919. In the Brackenbury Professorship, he was succeeded by A. V. Hill.
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Diktyoma is classified into teratoid and nonteratoid types, based on heteroplastic tissue in the former. Each type may be sub- classified as benign or malignant based on histology. Based on histology, the tumor is classified as malignant if it contains poorly differentiated neuroblasts, nuclear pleomorphism, markedly abnormal mitotic activity, sarcomatous components, or invasion into the uvea, cornea, or sclera. Most diktyomas are malignant.
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Methyl green is a closely related dye used as a stain in histology. Methyl green and ethyl green are very similar and probably interchangeable.
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Armand de Ricqlès is a French paleontologist best known for his work in bone histology and its implications for the growth of dinosaurs (e.g.).
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In histology, the HOPS stain is a way of marking tissue for microscopic examination. HOPS is an acronym for haematoxylin, orcein, phyloxin and saffron.
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Cresyl violet is an organic compound with the chemical formula C19H18ClN3O. It is a basic dye and is used as a common stain in histology.
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Burkitt HG, Young B, Heath JW. Wheater's Functional Histology: a text and colour atlas. Churchill Livingstone, London, 1993. The ileocecal valve has a papillose structure.
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Diagnosis of this type of lung cancer is by biopsy, histology and special staining. CT and colonoscopy to rule out a colonic primary are recommended.
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Histology and Histopathology is a monthly peer-reviewed medical journal publishing original and review articles in the fields of histology and histopathology. It was established in 1986 and is published by the University of Murcia in Spain. The editors-in-chief are Francisco Hernández and Juan F. Madrid (University of Murcia). According to the Journal Citation Reports, the journal has a 2016 impact factor of 2.025.
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Micrograph of a HPS stained section demonstrating perineural spread of prostate adenocarcinoma. In histology, the HPS stain, or hematoxylin phloxine saffron stain, is a way of marking tissues. HPS is similar to H&E;, the standard bearer in histology. However, it differentiates between the most common connective tissue (collagen) and muscle and cytoplasm by staining the former yellow and the latter two pink,"Saffron". polysciences.com.
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It has been shown that the subcellular location of stained proteins can be identified from histology images. If the goal is a medical diagnostic, then histology applications will often fall into the realm of digital pathology or automated tissue image analysis, which are sister fields of bioimage informatics. The same computational techniques are often applicable, but the goals are medically- rather than research-oriented.
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In 1875, he joined the faculty of histology at the University of Pavia. In 1879, he was appointed Chair of Anatomy at the University of Siena. But the next year, he returned to the University of Pavia as full Professor of histology. From 1879 he also became Professor of General Pathology as well as Honorary Chief (Primario ad honorarem) at the San Matteo Hospital.
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He served as the chief pathologist at the Army Hospital in Mexico City and was Professor of Histology and Pathology at the Mexican Army Medical School.
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Urachal cancer usually is an adenocarcinoma (about 90%) mostly with mucinous/colloidal histology. Other rare types include urothelial carcinoma, squamous cell carcinoma, neuroendocrine carcinoma and sarcoma.
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Botha, J. and Chinsamy, A. (2004). Growth and life habits of the Triassic cynodont Trirachodon, inferred from bone histology. Acta Palaeontologica Polonica 49(4):619-627.
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Martin Barry, MD, FRCPE, FRSE, FRS (28 March 1802, Fratton, Portsmouth, Hampshire - 27 April 1855, Beccles, Suffolk), was a British physician who studied histology and embryology.
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Some branches of zoology include: anthrozoology, arachnology, archaeozoology, cetology, embryology, entomology, helminthology, herpetology, histology, ichthyology, malacology, mammalogy, morphology, nematology, ornithology, palaeozoology, pathology, primatology, protozoology, taxonomy, and zoogeography.
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Anatomy, Physiology, Biochemistry, Histology, Embryology, Pathology, Pharmacology, Forensic Medicine, Microbiology, Community Medicine, Clinical Orientation, Internal Medicine, Surgery, Diagnostics, Pediatrics, Gynecology & Obstetrics, Otolaryngology, Neurology, Infectious Diseases, Emergency Medicine.
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A chromophil biological cell is a cell which is easily stainable by absorbing chromium salts used in histology to increase the visual contrast of samples for microscopy.
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Ross and Pawlina. Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone (DHEA) and androstenedione from cholesterol.Wheater's Functional Histology, 5th ed. Young, Lowe, Stevens and Heath.
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Medical Histology by Laiq Hussain Siddiqui (6th Edition) An odontoclast (/odon·to·clast/; o-don´to- klast) is an osteoclast associated with absorption of the roots of deciduous teeth.
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Cross section of a typical theropod dinosaur tooth in side view. All dinosaur teeth possess the same tissue types but can differ in their appearance. Various major groups of dinosaurs have been examined through histology, these include the carnivorous theropods and herbivorous groups such as the sauropods, hadrosaurs and ceratopsians. Listed below are some of the dental anatomy that has been identified through histology and interpretations on their significance.
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Here he distinguished himself by way of research in the fields of histology and microbiology. Eventually he attained the title of "libero docente" (equivalent of privat-docent) in histology and general pathology. In 1921 he established a bacteriology laboratory in the medical clinic at Pavia. In 1930 he was successor to Aldo Perroncito (1882-1929) as professor of general pathology, a position he kept until his retirement in 1942.
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He never returned to Serbia again. In 1925, when Professor Karpov was called back to Moscow, to resume his former duties, Dr. Marić succeeded Karpov as Chair of the Histology Department of the university. In 1928, Dr. Marić received a full professorship at the university. In 1930, he was elected Head of the Department of Histology at the Saratov State Medical University in the Russian city of Saratov.
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The first year curriculum consists of four blocks covering the basic medical sciences. Each block combines daily lectures by faculty from diverse fields, and therefore provides a highly integrated curriculum. The first block, titled Principles of Medicine, includes cellular and molecular biology, biochemistry, microbiology, pharmacology, histology, and genetics. The second, Immunology, is focused on the human immune system at the cellular level with specific focuses on histology, microbiology, and pharmacology.
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Rarely, cryosections are used to detect the presence of substances lost in the traditional histology technique, for example lipids. They can also be used to detect some antigens masked by formalin. The cryostat is available in a small portable device weighing less than , to a large stationary device or more. The entire histologic laboratory can be carried in one portable box, making frozen section histology a possible tool in primitive medicine.
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In 1895, Gage became a Professor of Anatomy, Histology, and Embryology. In 1908, Gage retired as Professor Emeritus of Histology and Embryology. Gage came out of retirement in 1918 returning to teaching as a result of the shortage of teachers caused by World War I. In addition to his work on microscopy and optic projection, Gage did research on the newt, toad, lamprey, on fat digestion and on the pancreas.
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Famed Spanish histologist Ramon y Cajal recognized Simarro's achievement, and mentioned that it was a milestone that allowed him to abandon general histology and to focus on neurohistology.
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They can be identified in histology by staining with a heavy metal like silver or the PAS stain that stains carbohydrates. Gordon and Gold can also be used.
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Dawson JD. The Histology of Disseminated Sclerosis. Trans Royal Soc Edin. 1916; 50: 517-740. This work formed the basis for his DSc thesis in the same year.
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Dinosaurs: Concepts, Histology and Stratigraphy. Gordon and Breach Science Publishers. pp. 302-303. This view was rejected by scientists as dinosaurs went extinct approximately 66 million years ago.
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Histology, virus isolation, electron microscopy, immunoperoxidase and immunofluorescent staining, immunodiffusion, complement fixation, virus neutralisation and ELISA can all be used to confirm diagnosis. Generally no treatment is required.
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Pictogram of CCPDMA or Margin Controlled Histology Pictogram of Standard Bread Loafing Histology False Negative in Standard Bread Loafing Histology Comparing Mohs Method to Smashing an Aluminum PiepanHow a Mohs Section is Flattened with Relaxing Incisions Mohs surgery is not suitable for all skin cancers. Mohs micrographic surgery is the most reliable form of margin control; utilising a unique frozen section histology processing technique - allowing for the complete examination of 100% of the surgical margin. The method is unique in that it is a simple way to handle soft, hard-to-cut tissue. It is superior to serial bread loafing at a 0.1 mm interval for improved false negative error rate, requiring less time, tissue handling, and fewer glass slides mounted. The clinical quotes for cure rate of Mohs surgery are from 97% to 99.8% after 5 years for newly diagnosed basal-cell cancer (BCC), decreasing to 94% or less for recurrent basal-cell cancer.
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NWNU is among the first to be entitled the numbi degree granting authority ratified by the State Council to confer bachelor's degree, Master's Degree and Doctorate since 1982. At present, the University has 6 postdoctoral research centers for Pedagogy, Chinese Language and Literature, Histology, Mathematics and Chemistry; 7 first-grade disciplines (Pedagogy, Chemistry, Chinese Language and Literature, Histology, Mathematics, Physics, Geography), 50 second-grade disciplines and 1 specialty with Doctorate granting authority; 32 first-grade disciplines,157 second-grade disciplines and 11 specialties with master's degree granting authority; 2 national key disciplines, 1 innovation team under the Ministry of Education, 16 provincial- level key disciplines, 33 university-level key disciplines and 66 Bachelor's specialties such as English, Mathematics and Applied Mathematics, Art, Chinese Language and Literature, Geography, Physics, Histology, Chemistry and Bio- Science. NWNU has established a fairly good academic degrees accreditation system, covering 10 academic fields such as Philosophy, Economics, Law, Pedagogy, Literature, Histology, Science, Engineering, Management and Art.
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An American Text-book of Pathology edited by Ludvig Hektoen, David RiesmanQuarterly Journal of Microscopical Science, Volume 8 He also made contributions in his research of cell division in vivo, on the histology of the cornea, and on the relationship of cells to the extracellular matrix. Among his written works is the ', a two-volume textbook that contains Stricker's essays on histology, along with treatises from several other prominent physicians and scientists, such as Max Schultze, Wilhelm Kühne, Joseph von Gerlach, Siegmund Mayer, Heinrich Wilhelm Waldeyer, Theodor Meynert, Ewald Hering, et al. During its time, it was considered one of the greatest textbooks concerning histology. Stricker was also the author of a number of philosophical works.
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Histology shows lipid-laden macrophages in the marrow and "sea-blue histiocytes" on pathology. Numerous small vacuoles of relatively uniform size are created, giving the cytoplasm a foamy appearance.
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These are more evidently grooved, with more pronounced ridges. They are extensively ciliated and are believed to serve an olfactory purpose.Fukuda, Y. 1987. Histology of the long digital tentacles.
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He has also made some contributions to the history of bone histology, and has written some papers on the problems facing French scientists because of the infamous French bureaucracy.
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Light microscopic histology of the retinal pigment epithelium of autosomal albinos was done in the original study by Warren, but subsequent light or electron microscopic studies of autosomal albino eyes or feathers have not been reported. The histology of the iris showed no evidence of pigmentation. At the ultra-structural level, small, spherical, poorly pigmented granules were seen in autosomal albino retinal melanocytes. In 1940 WarrenWarren, D.C. 1940 Inheritance of pinkeye in the fowl.
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Netter's Essential Histology is a textbook/atlas of human histology authored by William K. Ovalle and Patrick C. Nahirney. Drawings by medical illustrator, Frank H. Netter, with contributing artwork by James A. Perkins, Joe Chovan, John A. Craig, and Carlos A.G. Machado, are in the book. First published in English in 2008 by Elsevier/ Saunders, a 2nd edition was released in 2013. Subsequent editions in Portuguese, Korean, Greek, Turkish, and Italian have also been printed.
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Age determination studies using growth ring counts suggest that the longevity of C. rhodesiensis was approximately seven years.Chinsamy, A., (1994). Dinosaur bone histology: Implications and inferences. In Dino Fest (G.
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First-line treatment for metastatic PRCC has not been standardized. Thus, similar treatment approaches for clear cell RCC have been used for PRCC, even though it has a distinct tumor histology.
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The prosauropod Massospondylus carinatus 15 years of age,Chinsamy, A. (1994). Dinosaur bone histology: Implications and inferences. In Dino Fest (G. D. Rosenburg and D. L. Wolberg, Eds.), pp. 213-227.
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Maximow wrote "the world's most respected textbook in histology," a book that became a standard text for medical students and ran to 12 editions. He also developed and introduced a unitarian theory of hematopoiesis, a theory upon which the modern concept of blood cells' origin and differentiation is based. For four years before Maximow's death, fellow histologist William Bloom worked closely with him on the Textbook of Histology. Bloom ultimately completed the work, which was first published in 1930.
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It is highly encouraged that a physician interested in learning Mohs surgery should spend extended time observing, cutting, processing, and staining Mohs specimens. The histology block should be correctly mounted and cut the first time, as there is no second chance in Mohs histology. It is not a procedure that can be taught or learned in a short period of time. Many residency and Mohs fellowship continue to teach the processing of only 2 Mohs sections per tumor.
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In 1903 Goldschmidt began working as an assistant to Richard Hertwig at the University of Munich, where he continued his work on nematodes and their histology, including studies of the nervous system development of Ascaris and the anatomy of Amphioxus. He founded the histology journal Archiv für Zellforschung while working in Hertwig's laboratory. Under Hertwig's influence, he also began to take an interest in chromosome behavior and the new field of genetics. How the term intersex was coined.
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Tangl was born the son of a cloth-maker in Budapest in 1866. He attended the University of Budapest and graduated with a degree in medicine. He next was provided with a one-year traineeship for general hospitals and medical institutions, and spent half a year in 1887 in Kiel, dealing primarily with histology. On April 1 of the same year, he received a post as an assistant in histology in the medical school’s embryology division at Graz.
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She earned her medical doctorate in 1921. After her doctorate she took a job at the University of Milan, where she started research into histology. In addition to her role at the university Pastori took on a volunteer role at the hospital in Milan, and later a paid role at a nursing home. She was later granted a scholarship from the Italian Medical Women's Association, which afforded her access to the histology laboratory at the University of Rome.
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Researchers have also confirmed astroblastoma distinct from oligodendroglioma, which are invasive nodular cysts that may resemble a "bubbly" interior. Pleomorphic xanthoastrocytoma, dysembryoplastic neuroepithelial tumors, juvenile pilocytic astrocytoma, and hemangioblastoma are well-established, pediatric brain cancer tumors that are often confused with astroblastoma patients. However, further histology has confirmed that special structures and characteristics are unique to astroblastoma. Advances in the 21st century of histology have justified proper diagnosis, eliminating inconsistency that plagued this tumor for several decades.
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Duodenal cancer is a cancer in the first section of the small intestine. Cancer of the duodenum is relatively rare compared to stomach cancer and colorectal cancer. Its histology is usually adenocarcinoma.
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In particular, issues related to development anatomy (embryology), microscopic anatomy (histology and Citology), human anatomy, veterinary anatomy, comparative anatomy, neuroanatomy, neurobiology, radiological anatomy, clinical anatomy, anthropology, biophysics and biochemistry, etc. are discussed.
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Am. J. Clin. Path. 6, 196-197. The methods, techniques and stain she developed are well-known and utilized in histology and other fields of pathology to this day.Cain, Edmund F. (1934).
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Thioflavins are dyes used for histology staining and biophysical studies of protein aggregation. For example, thioflavin T is used in the RT-QuIC technique to detect transmissible spongiform encephalopathy-causing misfolded prions.
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In 1922 and 1923, he studied in Leipzig, Germany under Prof. Hooke on the mast cells in histology and became Ph.D. In 1939, he was the president of the leprosy congress at Aomori.
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This spreading apart of the microvilli aids cells in absorption. link link linkRoss, Michael H., and Wojciech Pawlina. "Chapter 5: Epithelial Tissue." Histology: a Text and Atlas : with Correlated Cell and Molecular Biology.
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Letty Moss- Salentijn, Biology of Mineralized Tissue coursenotes, Columbia University College of Dental Medicine, 2009Nanci, Antonio. Ten Cate's Oral Histology: Development, Structure, and Function. 7th ed. St. Louis, MO: Mosby Elsevier, 2008. Print.
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The cumulative relative survival rate for all age groups and histology follow-up was 60%, 52%, and 47% at 5 years, 10 years, and 20 years, respectively, with children doing better than adults.
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His study of psychiatry was complemented by work on the histology of the central nervous system. Biological psychiatry was prominent in Europe, and Sakaki came to view mental illness as having organic underpinnings.
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His discovery established how the oxygen breathed in enters the blood stream and serves the body. In the 19th century histology was an academic discipline in its own right. The French anatomist Xavier Bichat introduced the concept of tissue in anatomy in 1801, and the term "histology" (), coined to denote the "study of tissues", first appeared in a book by Karl Meyer in 1819. Bichat described twenty-one human tissues, which can be subsumed under the four categories currently accepted by histologists.
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PFTL is an extremely indolent disease which is manifested by lesions that exhibit a typical FL histology or, more commonly, a mixed FL-diffuse large cell lymphoma histology. It usually involves a 2-4 centimeter lesion in a single testicle. Patients have been treated with removal of the involved testes followed by various standard anti- lymphoma chemotherapy regimens to attain excellent results, i.e. 100% completed remissions with no recurrence of disease in 15 child and adolescent patients observed for 4–96 months.
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The mesocortex is essentially the same as paralimbic cortex, as all mesocortical transitional areas are found exclusively in paralimbic region, and vice versa - all the paralimbic cortex is mesocortical in its nature (embryonic and phylogenetic origins) and in its histology. But the term "mesocortex" represents a different concept from the term "paralimbic cortex". The mesocortex is distinguished from other cortical areas based on cytoarchitectonics and histology, while the paralimbic cortex is an anatomical designation, meaning cortical areas near subcortical limbic structures.
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Mathias-Marie Duval Mathias-Marie Duval (7 February 1844 – 28 February 1907) was a French professor of anatomy and histology born in Grasse. He was the son of botanist Joseph Duval-Jouve (1810–1883).
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In histology, the GFAP stain is done to determine whether cells contain glial fibrillary acidic protein, a protein found in glial cells. It is useful for determining whether a tumour is of glial origin.
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The intermediate pigment-containing cells are scattered among capillaries. The basal cells separate stria vascularis from the underlying spiral ligament.Ross, Michael H. Histology : a text and atlas / Michael H. Ross, Wojech Pawlina., -6th ed.
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Active ossifying fibroma must be separated from fibrous dysplasia, cementoblastoma, and meningioma. This type of separation must be made with the aid of imaging studies, and should not be done by histology examination only.
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It was introduced to histology by American neuropsychiatrist and pathologist Ira Van Gieson.Jocelyn H. Bruce-Gregorios, M.D.: Histopathologic Techniques, JMC Press Inc., Quezon City, Philippines, 1974. , BAN CROFT, Mahendra Jain A.C.P.M Dental College India.
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M. Kohn is the birth name of Moritz Kaposi (1837–1902). In 1876, Mikulicz contributed to the microscopic histology. In 1882, Anton Von Frisch (1849–1917) discovered the gram-negative bacillus which causes the disease.Frisch.
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Ambady, N., Bernieri, F. J., & Richeson, J. A. (2000). Toward a histology of social behavior: Judgmental accuracy from thin slices of the behavioral stream Advances in experimental social psychology (Vol. 32, pp. 201-271): Elsevier.
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They are found between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule.Ross, M.H. & Pawlina, W. 2003. Histology: A Text and Atlas, 4th Edition. Lippincott Williams & Wilkins, Philadelphia.
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In 1895, she began medical studies at the University of Michigan; she earned her Doctor of Medicine degree in 1898 and Bachelor of Science degree in 1899. Lydia and Alton DeWitt separated during this time. DeWitt remained at University of Michigan for the beginning of her career in research. She held a position under George Dock as a demonstrator of anatomy from 1896–1897, while she was still studying medicine, then became an assistant professor of histology until 1902, and associate professor of histology from 1902–1910.
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Regardless of methodology, the analysis of testis biopsy histology lacks clinical value in cases of infertility because there is no clear correlation between histologic patterns or Johnsen score and the underlying etiology of infertility. That is to say, the clinical utility of understanding the histology pattern is low, because biopsy patterns do not correlate well with specific and correctable diseases. In addition, the interobserver variability in testis biopsy readings for infertility is significant. This was aptly demonstrated in a study by Cooperberg et al.
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Teaching activities (1985–present) at Georgetown University include course director of cell biology/histology across multiple modules for 1st and 2nd year medical students as well as specific lectures therein. Additionally, lectures are given to post-graduate students in the Medical School at Georgetown University. Djakiew is also course director and lecturer of cell biology/histology held at the Prince William Campus of George Mason University for the GeorgeSquared program, a collaborative course of post-graduate studies between Georgetown University and George Mason University.
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Micrograph showing cryptitis in a case of Crohn's disease. H&E; stain. In histology, cryptitis refers to inflammation of an intestinal crypt. Cryptitis is a non-specific histopathologic finding that is seen in several conditions, e.g.
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Lillie's trichrome is a combination of dyes used in histology. It is similar to Masson's trichrome stain, but it uses Biebrich scarlet for the plasma stain. It was initially published by Ralph D. Lillie in 1940.
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Kanter was born in Zürich, Switzerland. His father, Mehmet Kanter, received his M.D. from the University of Zurich. The family then returned to Turkey. Enes' father became a professor of histology and genetics at Trakya University.
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Berkovits BKB, Holland GR, Moxham BJ. (2002). Oral Anatomy, Histology and Embryology. Mosby. 3rd edn. pp. 125. . Dentinal sclerosis/transparent dentin-sclerosis of primary dentin is regressive alteration in tooth characterized by calcification of dentinal tubules.
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The role of the mesonephros in the development of the sheep fetal ovary. Annales de Biologie Animal Biochimie et Biophysique 19, 1153-78. Recently this hypothesis has been challenged with some thorough histology. Sawyer et al.
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Recent studies suggest a shorter lifespan than modern Tuatara, based on irregular spacing of growth marks. Histology shows that the number of growth rings in Palaeopleurosaurus was smaller than the living tuatara, possibly indicating a shorter lifespan.
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Donald du Toit, FCS., FRCS.,PHD., D.Phil.(OXON) is a specialist general surgeon, clinician and emeritus professor as well as chief of Anatomy and Histology and previous ad hominem professor of surgery at the University of Stellenbosch.
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The gland receives its blood supply from the facial and lingual arteries.Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 255 The gland is supplied by sublingual and submental arteries and drained by common facial and lingual veins.
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The presence of odontoblastic processes here allows the secretion of matrix components. Predentin can be 10-40μm in width, depending on its rate of deposition.Berkovits BKB, Holland GR, Moxham BJ. (2002). Oral Anatomy, Histology and Embryology. Mosby.
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Born in Durban, Natal on 14 October 1925, the only son and second child of Joseph Newman Tobias and his wife, Fanny (née Rosendorff), Phillip received his first schooling in Bloemfontein at St Andrew's School and in Durban at the Durban High School. In 1945, he started his career as demonstrator in histology and instructor in physiology at the University of Witwatersrand. He received his Bachelor of Science (Hons) in Histology and Physiology in 1946–1947. In 1948 he was elected President of the National Union of South African Students (NUSAS).
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"Does Commercial aloe Vera Protects the Structure of the gastric mucosa against acute nonsteroidal anti-inflammatory drug (diclofenac sodium)-induced damage?". The Egyptian Journal of Histology, Vol. 34, No.1 # Samar M. Al-Saggaf, Soad Shaker Ali, Nasra Naeim Ayuob, Ashwaq Hassan Batawii and Mohammed Ibrahim Mujalled ( 2011). "Histological study on the effect of gasoline on guinea pig epidermis: can flavonoid extract reverse this effect?". The Egyptian Journal of Histology, 34:156–165, 14 (1251 - 2011). # Adnan A. Al-Marzooa, Nasra N. Ayuob, Basem S. El-Deek, Samar M. Alsaggaf, and Abdulaziz M. Boker (2011).
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Typically, the lesions are suspected to be schwannomas or neurofibromas clinically with PEN being an incidental finding on histology. PEN is typically diagnosed in patients between the ages of 40 and 60 years and occurs more frequently in females than males. The diagnosis of PEN may be difficult, even with confirmatory histology, due to its histological similarities with schwannomas and neurofibromas. It is imperative that the correct diagnosis is made the misdiagnosis of a neurofibroma may lead to unnecessary further investigation into associated systemic syndromes such as neurofibromatosis type 1 or multiple endocrine neoplasia syndrome.
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Hillarp was the son of merchant Nils Bengtsson and Hulda, former Johansson, and the brother of Rut Hillarp, a novelist. He became Doctor of Medical Science (equivalent to a Ph.D.) in 1946. He was appointed assistant and later associate professor of Histology at the University of Lund (1946–1962). The Swedish Medical Research Council enabled him to spend 1960 to 1962 in research at the Department of Pharmacology, University of Gothenburg, then in 1962 he became full professor of Histology at the Karolinska Institute in Stockholm, Sweden where he remained until his death in 1965.
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Richard Paltauf (9 February 1858 - 21 April 1924) was an Austrian pathologist and bacteriologist born in Judenburg, Styria. In 1880 he received his medical doctorate at the University of Graz, and from 1881 to 1883 was an assistant to pathologist Hans Kundrat (1845-1893) in Graz. Afterwards, he remained as Kundrat's assistant at the University of Vienna, where in 1888 he obtained his habilitation in pathological anatomy. In 1892 he became an associate professor of general pathology and pathological histology, and during the following year became head of the institute for pathological histology and bacteriology.
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Successful reprogramming was determined by performing histology and electrophysiological tests to confirm the tissue behaved as functional neurons. Beyond inducing neurons, Gallego-Perez et al also set out to induce endothelial cells in an ischemic mouse limb that, without proper blood flow, becomes necrotic and decays. Using a patented cocktail of plasmids (Etv2, Fli1, Foxc2, or EFF), these factors were delivered to the tissue above the surgery site. Using various methods, including histology and laser speckle imaging, perfusion and the establishment of new vasculature was verified as early as 7 days post- treatment.
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A variety of tests for the presence of BFDV are available: standard polymerase chain reaction (PCR), quantitative PCR (qPCR) which can detect the virus in extremely small quantities, whole-genome sequencing, histology, immunohistochemical tests, and quantitative haemagglutination assays.
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Currently there is intense interest in developing techniques for in vivo histology (predominantly using MRI), which would enable doctors to non-invasively gather information about healthy and diseased tissues in living patients, rather than from fixed tissue samples.
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There he vigorously involved himself in the construction of a hospital in Heidelberg-Bergheim. He died in Heidelberg at the age of 39 from diphtheria. As a pathological anatomist, Weber specialized in the fields of histology and histogenesis.
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Newer microtomes have electric push button advancement of the tissue. The precision of the cutting is in micrometres. Tissue are sectioned as thin as 1 micrometre. Usual histology slides are mounted with a thickness of about 7 micrometres.
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Barbara Chase was born in Philadelphia, Pennsylvania, the only child of Vivian May Chase, a histology technician, and Charles Edward Chase, a contractor.Smith, Jessie C. 1991. "Barbara Chase Riboud", in Notable Black American Women, p. 177 (Gale Cengage).
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1907–1910: McClendon taught biology at Randolph-Macon College, then zoology at the University of Missouri. 1910–1914: McClendon was Assistant, Instructor in histology and embryology of the Weill Cornell Medical College of Cornell University.Cornell University Information Database.
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Oral Histology: development, structure, and function. 5th ed. 1998. Page 155. . The major branches are the terminal ends of the tubules. About every 1-2 μm, there are fine branches diverging from dentinal tubules at 45 degree angles.
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An isogenous group (lat. "equal origin") is a cluster of chondrocytes, all formed through division of a single progenitor cell, found in hyaline cartilage and elastic cartilage, growing by interstitial growth.Wheater's Functional Histology, 6th ed. Young, O'Dowd and Woodford.
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Illustration of human gastrointestinal tract The structure and function can be described both as gross anatomy and as microscopic anatomy or histology. The tract itself is divided into upper and lower tracts, and the intestines small and large parts.
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Livia Puljak (born October 25, 1977 in Split, SFR Jugoslavia) is a Croatian scientist and associate professor at the Faculty of Medicine in Split. She is the head of the Department of Histology and Embryology, Faculty of Medicine, Split.
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Recently, this hypothesis has been challenged with some thorough histology. Sawyer et al. hypothesized that in sheep most of the granulosa cells develop from cells of the mesothelium (i.e., epithelial cells from the presumptive surface epithelium of the ovary).
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Janus Green B is a basic dye and vital stain used in histology. It is also used to stain mitochondria supravitally, as was introduced by Leonor Michaelis in 1900.Michaelis, L. (1900). Die vitale Farbung, eine Darstellungsmethode der Zellgranula.
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SIU SOM Histology GI Striated ducts are part of the intralobular ducts. They are found in the submandibular gland, sublingual duct, and the parotid gland, but are more developed in the parotid gland. They are not present in pancreas.
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Using histology on its own is insufficient, as these findings have been acknowledged not to distinguish, and even positive patch testing does not rule out the existence of an irritant form of dermatitis as well as an immunological one.
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Quekett served as the society's secretary from 1841 to 1860. In 1843 he was appointed assistant conservator of the Hunterian Museum, and in 1856 conservator of the museum and professor of histology on the retirement of professor Richard Owen.
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Palaeobates is an extinct genus of prehistoric elasmobranch sharks in the order Hybodontiformes. It lived during the Triassic period. Palaeobates had a grinding-type dentition, which it used to crush hard-shelled prey. The teeth exhibit an orthodont histology.
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He became assistant surgeon in 1849 and took Bransby Cooper's position after the latter retired, in 1853. An early advocate of histology, he introduced the teaching thereof in 1845, and subsequently promoted the use of histopathology in cancer diagnosis.
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At Mayo, de Galantha developed several novel methods and techniques in the field of histology. The de Galantha technique and the de Galantha stain bear her name for this work.de Galantha, Elena. (1932). "Modified silver stain for Treponema pallidum".
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Albert Edward Mettam MRCVS, MRIA (1867- 27 November 1917), was inaugural Principal of the Royal Veterinary College of Ireland in Dublin. He went there from The Royal (Dick) Veterinary College where he had been Professor of Anatomy and Histology from 1892.
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Also an incomplete layer of smooth muscle also lines the walls of these channels. The stroma consists of loose connective tissue with a lot of inflammatory cells. These tumors usually penetrate muscle. Cystic hygroma is indistinguishable from cavernous lymphangiomas on histology.
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The colonoscopy is normal but histology of the mucosal biopsy reveals an accumulation of lymphocytes in the colonic epithelium and connective tissue (lamina propria). Collagenous colitis shares this feature but additionally shows a distinctive thickening of the subepithelial collagen table.
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Prof Magnus Gustaf (or Gustav) Retzius FRSFor HFRSE MSA (17 October 1842 – 21 July 1919) was a Swedish physician and anatomist who dedicated a large part of his life to researching the histology of the sense organs and nervous system.
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Toothfishes are large in size, with both species reaching maximum sizes exceeding 100 kg.Eastman J.T. and DeVries A.L. (2000). Aspects of body size and gonadal histology in the Antarctic toothfish, Dissostichus mawsoni, from McMurdo Sound, Antarctica. Pol. Bio. 23, 189-195.
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It is descriptive and functional. Basically, it covers the gross anatomy and the microscopic (histology and cytology) of living beings. It involves both development anatomy (embryology) and the anatomy of the adult. It also includes comparative anatomy between different species.
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Histology is the study of the minute structure, composition, and function of tissues.Dorland's Medical Dictionary (Abridged 25th ed.). (1980). Philadelphia, PA: The Saunders Press. Mature human vocal cords are composed of layered structures which are quite different at the histological level.
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Orange G also called C.I. 16230, Acid Orange 10, or orange gelb is a synthetic azo dye used in histology in many staining formulations. It usually comes as a disodium salt. It has the appearance of orange crystals or powder.
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Long-bone histology enables researchers to estimate the age that a specific individual reached. A study by Eva Griebeler etal. (2013) examined long-bone histological data and concluded the Apatosaurus sp.SMA0014 weighed , reached sexual maturity at 21years, and died aged 28.
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Phosphomolybdic acid, also known as dodeca molybdophosphoric acid or PMA, is a yellow-green chemical compound that is freely soluble in water and polar organic solvents such as ethanol. It is used as a stain in histology and in organic synthesis.
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The first use of haematoxylin with eosin as a counterstain, which is currently the most used stain combination in histology, was first suggested by A. Wissowzky in 1876. By the early 1900s, haematoxylin had become widely accepted as a histologic stain.
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This step allows the development of the most adapted protocol for routine use of the biomarker. Simultaneously, it is possible to confirm the relevance of the protocol with various methods (histology, PCR, ELISA, ...) and to define strata based on the results.
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From the outer surface of the dentin to the area nearest the pulp, these tubules follow an S-shaped path. The diameter and density of the tubules are greatest near the pulp.Cate, A.R. Ten. Oral Histology: development, structure, and function.
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Elena de Galantha Elena de Galantha (24 November 1890 – 5 January 1986) was an Austro-Hungarian histologist. She is considered a pioneer in the field of modern histology and known for the de Galantha technique and the de Galantha stain.
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Within each organism, scale shape varies hugely according to body area, with intermediate forms appearing between different areas—and to make matters worse, scale morphology may not even be constant within one area. To confuse things further, scale morphologies are not unique to taxa, and may be indistinguishable on the same area of two different species. The morphology and histology of thelodonts provides the main tool for quantifying their diversity and distinguishing between species, although ultimately using such convergent traits is prone to errors. Nonetheless, a framework comprising three groups has been proposed based upon scale morphology and histology.
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Within each organism, scale shape varies greatly according to body area, with intermediate scale forms appearing between different areas; furthermore, scale morphology may not even be constant within a given body area. To confuse things further, scale morphologies are not unique to specific taxa, and may be indistinguishable on the same area of two different species. The morphology and histology of the thelodonts provides the main tool for quantifying their diversity and distinguishing between species – although ultimately using such convergent traits is prone to errors. Nonetheless, a framework of three groups has been proposed, based upon scale morphology and histology.
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Archipelepidiformes is an order of extinct jawless fishes in the class Thelodonti. Archipelepidiforms are regarded as the basalmost thelodonts primarily because the histology and morphology of archipelepidiforms have many similarities with the histology and morphology of pteraspidomorphs, hinting that the two groups share a common ancestor, and hinting that archipelepidiforms retain many primitive features from this common ancestor.Soehn, K. L., Märss, T., Caldwell, M. W. & Wilson, M. V. H., 2001: New and biostratigraphically useful thelodonts from the Silurian of the Mackenzie Mountains, Northwest Territories, Canada. Journal of Vertebrate Paleontology, 21: 651-659 Wilson, Mark VH, and Tiiu Märss.
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The entire process from mounting to reading the slide takes from 10 to 20 minutes, allowing rapid diagnosis in the operating room, for the surgical excision of cancer. The cryostat can be used to cut histology and tissue slide (e.g., for enzyme localization) outside of medicine, but the quality of the section is poor compared to standard fixed section wax mounted histology. Newer technology such as the Compresstome, a type of vibrating microtome, utilizes agarose tissue embedding instead of an optimal cutting temperature compound to eliminate the need for traditional cryostat freezing and may be used for improved quality sectioning.
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Haematoxylin or hematoxylin (), also called natural black 1 or C.I. 75290, is a compound extracted from heartwood of the logwood tree (Haematoxylum campechianum) with a chemical formula of . This naturally derived dye has been used as a histologic stain, ink and as a dye in the textile and leather industry. As a dye, haematoxylin has been called Palo de Campeche, logwood extract, bluewood and blackwood. In histology, haematoxylin staining is commonly followed (counterstained), with eosin, when paired, this staining procedure is known as H&E; staining, and is one of the most commonly used combinations in histology.
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The staff is full of youthful spirit, diligence and potential. The Fundamental Medicine Teaching Department includes Mathematics and Computer Science Section, College English and Majoring English Sections, Social Science Section, Physical Science Section, Section of Anthropotomy, Histology and Embryology, Physiology Section, Immunology and Pathogeny Section, Pathology Section, Preventive Medicine Section. The department also has some laboratories, such as anthropotomy, histology and embryology laboratory, enginery laboratory, pathogeny and parasitology laboratory, microbiology and immunology laboratory, computer and language laboratory. The Fundamental Medicine Teaching Department is charged with the teaching of 30 courses from clinic medicine, stomatology, nursing, bio-engineering, medicament.
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Google Books The Genesee Conodonts: with descriptions of new species by William Letchworth Bryant] In the spring of 1888, he relocated to St. Petersburg, where he served as a private tutor until 1895. Afterwards, he was an associate professor of histology (later for embryology) at the Karl- Ferdinands-Universität in Prague. In February 1903, he attained a full professorship of histology and embryology.Biographical information based on a translation from an equivalent article at the German Wikipedia His name is associated with "Rohon-Beard cells", defined as large mechanosensory neurons found in the dorsal spinal cord of fishes and amphibians.
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Museo Municipal Carmen Funes, Plaza Huincul, Argentina In a study published in PLoS ONE on October 30, 2013, by Bill Sellers, Rodolfo Coria, Lee Margetts et al., Argentinosaurus was digitally reconstructed to test its locomotion for the first time. Before the study, the most common way of estimating speed was through studying bone histology and ichnology. Commonly, studies about sauropod bone histology and speed focus on the postcranial skeleton, which holds many unique features, such as an enlarged process on the ulna, a wide lobe on the ilia, an inward-slanting top third of the femur, and an extremely ovoid femur shaft.
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It is believed that the process of acute rejection is mediated by the cell mediated pathway, specifically by mononuclear macrophages and T-lymphocytes. Histology of acute rejection is defined by dense lymphocytic cellular infiltrate as well as vasculitis of organ donor vessels.
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This analysis is not possible using traditional manual histology techniques due to the excessive time involved and lost sections due to folding and warping. 3Scan’s KESM technology is able to perform approximately a year’s worth of tissue sample processing in a single day.
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Bull Environ. Res. Vol.13, No.1 # Samar O. Rabah, Soad S. Ali, Samer M. Alsaggaf, Nasra N. Ayuob. (2010). "Acute Taxol Toxicity: the Effects on Bone Marrow Mitotic Index and the Histology of Mice Hepatocytes". J. Appl. Anim. Res. 38 201-207.
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Wesley Critz George (1888–1982) was an American academic. He was Professor of histology and embryology and Chair of the Department of Anatomy at the University of North Carolina at Chapel Hill from 1940 to 1949. He was a eugenicist and a segregationist.
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About 1 out of 1000 lesions are or become malignant, typically as a leiomyosarcoma on histology. A sign that a lesion may be malignant is growth after menopause. There is no consensus among pathologists regarding the transformation of leiomyoma into a sarcoma.
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Palaeoloxodon falconeri, also known as the pygmy elephant, Maltese pygmy elephant, or Sicilian dwarf elephant"dental histology of the sicilian dwarf elephant Palaeoloxodon falconeri.." (pdf). researchgate.net. 2015., is an extinct Siculo-Maltese species of elephant that was derived from the straight- tusked elephant.
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On April 16, 1868, Suslova married her first husband, Friedrich Erismann, in Vienna, Austria. They met while both students at the University of Zurich. The couple divorced on August 18, 1883. In 1885, Suslova married Aleksandr Golubev, a histology professor and physician.
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Depending on the clinical signs, histology of a skin biopsy may vary. There may be oedema in the epidermis with a dense superficial and deep lymphocytic infiltrate without vasculitis. Recently appearing lesions may show neutrophils. Spongiosis and vesicle formation may also be present.
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Journal of Paleontology 76(1): 156-172. The boundary with the underlying Javelina Formation has been estimated at about 66.5 million years old.Woodward, H. N. (2005). Bone histology of the sauropod dinosaur Alamosaurus sanjuanensis from the Javelina Formation, Big Bend National Park, Texas.
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Comparing Mohs Surgery Method to smashing an aluminum pie panHow a Mohs Section is flattened with relaxing incisions bread loafing histology: If the pathologist looks only at the margin of the three narrow slices, the many cancerous cells on the discarded margins will be missed.
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Limb bone In 2010, Koen Stein et al. studied the histology of Magyarosaurus. They found that even the smallest individuals appeared to be adults. They also retained "M." hungaricus to represent the larger specimens that were too big to be variations of the smaller specimens.
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These antibody staining methods often require the use of frozen section histology. These procedures above are also carried out in the laboratory under scrutiny and precision by a trained specialist medical laboratory scientist (a histoscientist). Digital cameras are increasingly used to capture histopathological images.
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The average long term risk of colon cancer is between 15 and 30%. However, the risk of cancer varies widely and depends on age, polyp burden, phenotype and the presence of dysplasia on histology. Endoscopic surveillance can decrease the risk of progression to cancer.
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Necropsy lesions in primates with callitrichid hepatitis show signs of jaundice, hepatomegaly, splenomegaly, and subcutaneous and intramuscular hemorrhages. Pleural and pericardial effusion, sometimes sanguineous, has also been reported. On histology, multifocal necrosis with acidophilic bodies and mild inflammatory infiltrates are typically found in the liver.
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Haematoxylin (hematoxylin in North America) is a nuclear stain. Used with a mordant, haematoxylin stains nuclei blue-violet or brown. It is most often used with eosin in the H&E; stain (haematoxylin and eosin) staining, one of the most common procedures in histology.
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The mutated cells are mature T-lymphocytes and contain CD4+ receptors on the membrane surface. There are two variants of this mutated cell, Lutzner cells and Sézary cells. Sometimes these names are interchangeable, but it has been determined through histology that they are morphologically different.
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In: Mescher AL. eds. Junqueira’s Basic Histology: Text and Atlas, 15e New York, NY: McGraw- Hill Necrosis begins after 20 minutes of an infarction. Under 4 hours of ischemia, there are no gross or microscopic changes noted.Kumar, V., Abbas, A. K., & Aster, J. C. (2015).
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Neutral red (toluylene red, Basic Red 5, or C.I. 50040) is a eurhodin dye used for staining in histology. It stains lysosomes red.Winckler, J. Vital staining of lysosomes and other cell organelles of the rat with neutral Red. Prog. Histochem. Cytochem. 6, 1–89 (1974).
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Marcoscopy On a macroscopic basis CMV Esophagitis may appear to be punched out lesions Microscopy Histology of CMV Esophagitis demonstrates enlarged cells with inclusions within both the cytoplasm and the nucleus of the cell. Also aggregates of macrophage cells are common on microscopic examination.
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And, the histiocytes in these lesions express CD68 and CD163 cell surface proteins. Before making a diagnosis of THRLBCL in a pediatric population, congenital and acquired immunodeficiency diseases, which can cause aberrant immune responses with a histology similar to THRLBCL, must be ruled-out.
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Basch's best-known work is Erinnerungen aus Mexico (1868), written at the request of Maximilian. In addition, he has written for technical journals a number of articles on the histology of the duodenum, the anatomy of the urinary bladder, and the physiological effects of nicotine.
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Long-bone histology enables researchers to estimate the age that a specific individual reached. A study by Griebeler et al. (2013) examined long bone histological data and concluded that the diplodocid MfN.R.2625 weighed , reached sexual maturity at 23 years and died at age 24.
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V.Sc.), Comparative Histology (Ph.D.), Doctorate in Veterinary Medicine (D.V.M.), and Veterinary Laboratory Sciences (B.Sc.). Academic members of the faculty are actively engaged in education and research in areas as diverse as clinical practice, domestic animal health and diseases, food safety, biology and public health.
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Reizner, J., 2010, An ontogenetic series and population histology of the ceratopsid dinosaur Einiosaurus procurvicornis. Montana State University master's thesis, pp 97 Like all ceratopsids, Einiosaurus had a complex dental battery capable of processing even the toughest plants. Einiosaurus lived in an inland habitat.
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4th edition. Page 450. . The dentinal tubules extend from the dentinoenamel junction (DEJ) in the crown area, or dentinocemental junction (DCJ) in the root area, to the outer wall of the pulp.Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 156.
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Spine (Phila Pa 1976), 2016. 41(8): p. E481-8. Baudrez, Galant, and VandeBerg found that MRI appearance is dictated by histology of the tumor—Vascularity, interstitial edema, and interspersed fat.Baudrez, V., C. Galant, and B.C. Vande Berg, Benign vertebral hemangioma: MR-histological correlation.
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Histology of a skin biopsy from acute phase eosinophilic cellulitis. Note findings of plentiful tissue eosinophils and flame figures at the deeper corium sections (hematoxylin & eosin, original magnification ×40). Diagnosis requires ruling out other potential causes. This includes ruling out vasculitis on skin biopsy.
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During the first two years of study, the curriculum includes basic theoretical subjects, such as anatomy, physiology, histology, embryology, biochemistry, and organic and inorganic chemistry. Clinical subjects, which begin in the third year, include gynecology, surgery, internal medicine, pediatrics, E.N.T., neurology, dermatology and psychiatry.
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In September 1943, de Galantha moved to Houston, Texas and secured a medical technologist position performing histopathological research at Baylor Medical College in the laboratory of Dr. Anthony A. Pearson, professor of anatomy. She handled microscopic samples for the departments of anatomy and histology.
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Stevens continued her education at Westfield Normal School (now Westfield State University) She completed the four-year course in two years and graduated with the highest scores in her class. Seeking additional training in sciences, in 1896, Stevens enrolled in newly established Stanford University, where she received her B.A. in 1899 and her M.A. in biology in 1900. She became increasingly focused on histology after completing one year of graduate work in physiology under Oliver Peebles Jenkins and his former student, and assistant professor, Frank Mace MacFarland. After studying physiology and histology at Stanford, Stevens enrolled in Bryn Mawr College to pursue her Ph.D. in cytology.
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In 1902 she began to teach in the Department of Anatomy at Johns Hopkins. By 1905 she was promoted to associate professor and finally appointed professor of embryology and histology in June 1917, the first woman to become a full professor at a medical college. In 1921, Sabin was named the first female president of the American Association of Anatomists. She continued her research on the origins of blood, blood vessels, blood cells, the histology of the brain, and the pathology and immunology of tuberculosis at Hopkins. In 1924, Sabin’s work on the origins of blood vessels earned her membership in the National Academy of Science.
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The treatment of adenocarcinoma of the lung depends on several factors including stage, resectability, performance status, histology and genomic alterations acquired by the individual tumor. As in most cancer types, treatment approaches can be broadly divided into 5 categories: surgery, chemotherapy, radiotherapy, targeted therapy and immunotherapy.
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The first professors are graduates of the higher veterinary schools in Berlin, Vienna, Lyon and Torino. International contests for heads of three major departments were announced. Thus, Assoc. Prof. Heinrich Bitner from Berlin was appointed for head of the Department of Anatomy, Histology and Embryology, Prof.
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Golding-Bird's trachea dilator Golding-Bird was known for his skill in microanatomy (histology). He worked by hand with an ordinary razor, as was then the custom. Drawings of his sections of the retina appeared in Quain's Anatomy.Plarr's Golding-Bird invented a dilator for use in tracheotomies.
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However, histology of the small specimens and restudy of the large specimens has shown that they each represent adult forms of two different species. The larger one-cusped morphotype was given a new species, T. hydroides, while the smaller tricuspid morphotype retained the name T. longobardicus.
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However, spinosaurids from the Romualdo Formation possibly attained greater sizes. Although LPP-PV-0042 is represented only by a tibia fragment, Aureliano and colleagues estimated its length at roughly . Bone histology indicates that this individual was a subadult, so the mature animal may have been larger.
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However, some mammals' teeth do develop differently than humans'. In mice, WNT signals are required for the initiation of tooth development. Rodents' teeth continually grow, forcing them to wear down their teeth by gnawing on various materials.Caceci. Veterinary Histology with subtitle "Digestive System: Oral Cavity" found here .
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Principal cells of the pars tuberalis are low columnar in form, with the cytoplasm containing numerous lipid droplets, glycogen granules, and occasional colloid droplets. A sparse population of functional gonadotrophs are present (indicated by immunoreactivity for ACTH, FSH, and LH).Ross, Michael. Histology: A Text and Atlas.
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Chinsamy-Turan, A. (2012). Forerunners of Mammals : Radiation, Histology, Biology (Life of the past). Bloomington: Indiana University Press. Another pattern of growth in some dicynodonts, including the closest relatives of Odontocyclops, is rapid growth as a juvenile followed by a decrease in growth rate with age.
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Long-bone histology enables researchers to estimate the age that a specific individual reached. A study by Griebeler et al. (2013) examined long-bone histological data and concluded that the Camarasaurus sp. CM 36664 weighed , reached sexual maturity at 20 years and died at age 26.
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Basic Histology, Text and Atlas.McGraw-Hill Companies. 2005. The unique myelocyte next differentiates into a metamyelocyte and then a band cell, with a "C" shaped nucleus, before becoming a mature eosinophil, basophil, or neutrophil. Macrophages come from monoblast progenitors that differentiate into promonocytes, which mature into monocytes.
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General medicine education in Iran takes 7 to 7.5 years. Students enter the university after high school. Students study basic medical science (such as anatomy, physiology, biochemistry, histology, biophysics, embryology, etc.) for 2.5 years. At the end of this period they should pass a "basic science" exam.
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She excelled academically, earning particularly high grades in botany and histology. She also studied Chinese and campaigned unsuccessfully for a smoke-free campus. Some of Hamilton's male Dalhousie classmates criticized her supposedly unfeminine dress and appearance, and created a petition to obtain a bustle for her.
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Beck, Kimberley G.; oler-Gijón, Rodrigo; Carlucci, Jesse R.; Willis, Ray E. (December 2014). "Morphology and Histology of Dorsal Spines of the Xenacanthid Shark Orthacanthus platypternus from the Lower Permian of Texas, USA: Palaeobiological and Palaeoenvironmental Implications". Acta Palaeontologica Polonica. 61 (1): 97–117. doi:10.4202/app.
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Sobotta was also the author of Atlas und Grundriss der Histologie und mikroskopischen Anatomie des Menschen (1902), later translated into English and published as Textbook and atlas of human histology and microscopic anatomy.WorldCat Identities (publications) In 1944 he was awarded the Goethe- Medaille für Kunst und Wissenschaft.
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Histology of bone showing osteitis fibrosa cystica. (Fibrosis and intratrabecular tunnels are seen). Cysts may be lined by osteoclasts and sometimes blood pigments, which lend to the notion of "brown tumors." Such cysts can be identified with nuclear imaging combined with specific tracers, such as sestamibi.
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The second book, Homo Sungirensis (2000) edited by T.I. Alexeeva et al., includes articles published since the first book, and new anthropological data derived from morphology, palaeopathology, X-ray study, histology, trace elements and molecular genetic analyses. It has an illustrated catalogue of all the skeletal materials.
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The full blood count, erythrocyte sedimentation rate and C reactive protein are normal. Synovial fluid is typically viscous, clear, honey-colored, and low in cell count. Synovial histology shows little or no mononuclear infiltration. Mild thickening of the synovium is present and giant cells may be occasionally seen.
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A liver biopsy stained using the reticulin demonstrating the normal hepatic plate thickness and mild steatosis. In pathology, the reticulin stain, is a popular staining method in histology. It is used to visualize reticular fiber and used extensively in liver histopathology.Lefkowitch JH. Special stains in diagnostic liver pathology.
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Enamel is the hardest substance in the human body and contains the highest percentage of minerals,Ross et al., p. 485 96%, with water and organic material composing the rest.Ten Cate's Oral Histology, Nancy, Elsevier, pages 70-94 The primary mineral is hydroxyapatite, which is a crystalline calcium phosphate.
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After 1908 he worked as a full-time academic in Istanbul University and Ankara University. He lectured histology and embryology. He notably contributed to the field of bacteriology via his research on microorganisms (tuberculosis, anthrax, cholera, syphilis, gonorrhea), and the field of virology by his research on rinderpest.
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He attended the University of Wisconsin, graduating with a bachelor of science degree in 1888. His science studies were in histology and embryology, and included making histological sections of tissues for study under the microscope. He went on to the University of Pennsylvania, gaining an M.D. in 1891.
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Low concentration fluoride ions act as bacteriostatic therapeutic agent and high concentration fluoride ions are bactericidal. The incorporated fluorine makes enamel more resistant to demineralization and, thus, resistant to decay.Ross, Michael H., Kaye, Gordon I. and Pawlina, Wojciech (2003). Histology: A Text and Atlas. 4th edition, p. 453. .
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He also wrote Outlines of Practical Physiology (1888) and Outlines of Practical Histology (1890). Stirling was in 1906–1909 Fullerian Professor of Physiology of the Royal Institution, London. He was a fellow of the Royal Society of Edinburgh and was elected in 1877 a member of the Physiological Society.
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The presentation is similar to that of other lung cancers. There is nothing in the radiological appearances that would suggest this particular histology. Two-thirds of reported cases have occurred in the right lung. The reason for this difference is not known and may be due to chance.
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Owen was impressed by the quality of the slides and in 1841 he purchased 1,500 of them for £150 to use in the teaching of surgeons. The slides are considered to be important in the history of medicine, histology and microscopy and they remain in the College's collection today.
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In 1910 he received a job offer at the university he graduated from and became an assistant professor at the Department of Histology at the University of Cluj. In 1913, according to some sources under his father's pressure, he married a wealthy girl by the name of Martha.
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Naphthol Green B is used in histology to stain collagen.Histological and Histochemical Methods: Theory and Practice, 4th edition, J. A. Kiernan Moreover, it is used for polychrome stains with animal tissue. For industry purposes Naphthol Green B is used for staining wool, nylon, paper, anoxidized aluminium and soap.
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1), October 1932, p.78-107 (digitized by the United States National Library of Medicine) In 1928, Popa became professor of anatomy at Iași,Petrovanu, p.20 the city associated with his rivals. For many years he taught Histology, Anatomical Pathology and Legal Medicine, as required,Petrovanu, p.
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In March 2018, scientists reported that Archaeopteryx was likely capable of flight, but in a manner distinct and substantially different from that of modern birds. This study on Archaeopteryxs bone histology suggests that it was closest to true flying birds, and in particular to pheasants and other burst flyers.
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EST can have a multitude of morphologic patterns including: reticular, endodermal sinus-like, microcystic, papillary, solid, glandular, alveolar, polyvesicular vitelline, enteric and hepatoid. Schiller-Duval bodies on histology are pathognomonic and seen in the context of the endodermal sinus-like pattern. Rarely, it can be found in the vagina.
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Bouin solution, or Bouin's solution, is a compound fixative used in histology. It was invented by French biologist Pol Bouin and is composed of picric acid, acetic acid and formaldehyde in an aqueous solution. Culling, C.F.A. 1974. Handbook of Histopathological and Histochemical Techniques (including museum techniques), 3rd ed.
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The diagnosis is generally suspected based on the appearance and confirmed by laboratory testing. The four main tests are a potassium hydroxide smear, culture, histology examination, and polymerase chain reaction. The sample examined is generally nail scrapings or clippings. These being from as far up the nail as possible.
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Vascular spaces fuse and become interconnected, forming the placenta, which supplies oxygen and nutrition to the embryo and fetus.Blue Histology - Female Reproductive System. School of Anatomy and Human Biology — The University of Western Australia Accessed 20061228 20:35 The speculated presence of an endometrial microbiota has been argued against.
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Unlike enamel, dentin may be demineralized and stained for histological study. dentin consists of microscopic channels, called dentinal tubules, which radiate outward through the dentin from the pulp to the exterior cementum or enamel border.Ross, Michael H., Gordon I. Kaye, and Wojciech Pawlina, 2003. Histology: a text and atlas.
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Kölliker's contributions to histology were widespread; smooth muscle, striated muscle, skin, bone, teeth, blood vessels and viscera were all investigated by Kölliker, and he touched none of them without discovering new truths. The results at which he arrived were recorded partly in separate memoirs, partly in his great textbook on microscopical anatomy, which first saw the light in 1850, and by which he advanced histology no less than by his own researches. Albert L. Lehninger asserted that Kölliker was among the first to notice the arrangement of granules in the sarcoplasm of striated muscle over a period of years beginning around 1850. These granules were later called sarcosomes by Retzius in 1890.
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They denied the existence of globules in tissue; Ernst Heinrich Weber in 1830 contradicted them, and the debate continued for a decade. For a while microscopy suffered in its reputation, but by 1840 histology was a recognised discipline, and in time the view of Hodgkin and Lister that "globules" were optical artefacts became accepted. The 1827 paper they published has been called "the foundation of modern histology". Hodgkin described the disease that bears his name (Hodgkin lymphoma) in 1832, in a paper titled On Some Morbid Appearances of the Absorbent Glands and Spleen. He received 33 years later the eponym through the recognition of British physician Samuel Wilks, who rediscovered the disease.
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In 1933, Amoroso went to London, where he was demonstrator in embryology and histology at University College London. Also in 1933, he began a PhD, which he received in 1934 for his work on the development of the urogenital system in rabbits. After a chance meeting with Hewlett Johnson, later to be known as the "red dean of Canterbury", Amoroso was told about an opening with the Royal Veterinary College (RVC) for a senior assistant for histology and embryology, and he successfully applied for the position, his appointment taking effect in October 1934. In his early days at the veterinary college, as the first staff member of colour, he was subjected to racism and resentment from some colleagues.
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A histology image of alveolar microlithiasis Histology is a microscopy application where tissue slices are stained and observed under the microscope (typically light microscope, but electron microscopy is also used). When using a light microscope, unlike the case of fluorescent imaging, images are typically acquired using standard color camera-systems. This reflects partially the history of the field, where humans were often interpreting the images, but also the fact that the sample can be illuminated with white light and all light collected rather than having to excite fluorophores. When more than one dye is used, a necessary preprocessing step is to unmix the channels and recover an estimate of the pure dye-specific intensities.
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The diagnosis of the intravascular large B-cell lymphoma, hemophagocytic syndrome-associated variant depends on the individual presenting with clinical and laboratory findings compatible with the hemphagocytic syndrome (see previous section) and on the histology of biopsied tissue(s) of the bone marrow, spleen, liver, brain, or other organ that clinical and/or laboratory findings suggest are involved in the disease. Its histology is described in the Diagnosis section of the classical variant but also includes the presence of hemophagocytosis, i.e. the engulfment of red blood cells and/or other mature and immature blood cells. Hemophagocytosis can also be found in sites removed from the intravascular lesions such as the cerebrospinal fluid in patients with central nervous system involvement.
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The H&E; staining procedure is the principal stain in histology in part because it can be done quickly, is not expensive, and stains tissues in such a way that a considerable amount of microscopic anatomy is revealed, and can be used to diagnose a wide range of histopathologic conditions. The results from H&E; staining are not overly dependent on the chemical used to fix the tissue or slight inconsistencies in laboratory protocol, and these factors contribute to its routine use in histology. H&E; staining does not always provide enough contrast to differentiate all tissues, cellular structures, or the distribution of chemical substances, and in these cases more specific stains and methods are used.
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There is some dispute about the control of mineralization during dentinogenesis.Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 173 The dentin in the root of a tooth forms only after the presence of Hertwig epithelial root sheath (HERS), near the cervical loop of the enamel organ. Root dentin is considered different from dentin found in the crown of the tooth (known as coronal dentin) because of the different orientation of collagen fibers, as well as the possible decrease of phosphophoryn levels and less mineralization.Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 174 Maturation of dentin or mineralization of predentin occurs soon after its apposition, which takes place two phases: primary and secondary.
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At the end of the 1800s, the development of very thin and consistently thin samples by microtomy, together with the selective staining of important cell components or molecules allowed for the visualisation of microscope details.Werner Linß, Werner Linb, Jochen Fanghänel: Histologie: Zytologie, allgemeine Histologie, mikroskopische Anatomie. (Histology: Cytology, general Histology, microscopial anatomy) Walter de Gruyter, 1998, (Google-Books) Today, the majority of microtomes are a knife-block design with a changeable knife, a specimen holder and an advancement mechanism. In most devices the cutting of the sample begins by moving the sample over the knife, where the advancement mechanism automatically moves forward such that the next cut for a chosen thickness can be made.
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The bone collar is a cuff of periosteal bone that forms around the diaphysis of the hyaline cartilage model in developing long bones.Wheater's Functional Histology, 5th ed. Young, Lowe, Stevens and Heath. The bone collar appears during endochondral bone development to support the growing bone and help it retain its shape.
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Diagram of a typical long bone showing both compact (cortical) and cancellous (spongy) bone. Histology of Osteon. The osteon or haversian system (named for Clopton Havers) is the fundamental functional unit of much compact bone. Osteons are roughly cylindrical structures that are typically between 0.25 mm and 0.35 mm in diameter.
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Freshmen students' courses include: Chemistry and Physics, Anatomy and Histology (General and Dental) and Physiology. However, junior students focus on Pathology (General and Dental), Bacteriology , Metallurgy, Prosthetic Dentistry and other things. Seniors on the other hand study, Oral Surgery, Orthodontia, Operative Dentistry, Crown and bridge-work, Laboratory work and Infirmary practice.
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The UT dental college is fully accredited by the Southern Association of Colleges and Schools. Curriculum for the college includes courses on the basic sciences, including biochemistry, microbiology, pathology, histology, and anatomy. Dental courses include advanced pain control, oral pathology, and advanced oral radiology. Several optional courses are also offered.
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It is an unrare form of cancer that originates in the lymph system and causes the destructive effects in the immune system.Lennert, K. (2012). Malignant Lymphomas Other than Hodgkin’s Disease: Histology, Cytology, Ultrastructure, Immunology. Philadelphia, Pennsylvania: Springer Science & Business. There are two types of lymphoma, Hodgkin’s lymphoma and non-Hodgkin’s lymphoma.
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The zona reticularis (sometimes, reticulate zone) is the innermost layer of the adrenal cortex, lying deep to the zona fasciculata and superficial to the adrenal medulla. The cells are arranged cords that project in different directions giving a net-like appearance (L. reticulum - net).Histology: A Text and Atlas, 5th ed.
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Size comparison The total length of Miragaia has been estimated at 5.5 – 6 metres (18–20 ft). In 2010, Gregory S. Paul estimated the length at 6.5 metres, the weight at two tonnes. Histology shows that the holotype specimen was about 21 years old. The describers established six distinguishing traits.
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The Sigma Logo. Sigma is the Sigma-Aldrich's main biochemical supplier, with offerings including antibiotics, buffers, carbohydrates, enzymes, forensic tools, hematology and histology, nucleotides, proteins, peptides, amino acids and their derivatives. The Sigma RBI Logo. Sigma RBI produces specialized products for use in the field of cell signaling and neuroscience.
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A study conducted by Botha-Brink and AngielczykBotha-Brink, J. & K. Angielczyk. 2010. Do extraordinarily high growth rates in Permo-Triassic dicynodonts (Therapsida, Anomodontia) explain their success before and after the end-Permian extinction? Zoological Journal of the Linnean Society 160: 341-365. reviewed the bone histology of Permo- Triassic dicynodonts.
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Like those of rabbits, rodents' incisors grow continuously throughout their lives, and are both aradicular and hypsodont. Unlike humans whose ameloblasts die after tooth development, rodents continually produce enamel and must wear down their teeth by gnawing on various materials.Caceci, Thomas. Veterinary Histology with subtitle "Digestive System: Oral Cavity" found here .
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Sebaceous glands secrete the oily, waxy substance called sebum () that is made of triglycerides, wax esters, squalene, and metabolites of fat- producing cells. Sebum lubricates the skin and hair of mammals.Dellmann's textbook of veterinary histology (405 pages), Jo Ann Coers Eurell, Brian L. Frappier, 2006, p.29, weblink: Books-Google-RTOC.
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He also trained in histology under Alexander Rollett. He became an associate professor in 1876 and joined the University of Chernivtsi where he established a zoology institute. Graber conducted experiments to demonstrate that cockroaches avoided light and sought the dark. He also examined the preferences for colours in various insects.
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Auramine phenol stain is a stain used in clinical microbiology and histology to identify tuberculosis mycobacteria. There are two types of auramine phenol stains, 1 and 2 to stain mycobacterium species and cryptosporidium respectively. Both are fluorescent stains. The bacteria or the parasites appear brilliant greenish yellow against dark background.
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In 1967, he was also appointed chair of the Department of Cell Biology and Histology. Wolman authored more than 200 publications and contributions to books. Over the years, he contributed chapters to many textbooks and served on numerous editorial boards including Histochemie. He was deeply interested in educational and ethical questions.
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Tor Ørvig (1916–1994) was a Norwegian-born Swedish paleontologist who explored the histology of early vertebrates. He was professor at the Swedish Museum of Natural History in Stockholm and member of the Royal Swedish Academy of Sciences. He described a possible post-Cretaceous coelacanth fossil from the Paleocene epoch.
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Heinrich Wilhelm Waldeyer in Strasbourg. His doctoral work was on the subject of the histology and development of the epidermis, and was published in 1876. The thesis contained a set of new ideas and aspects that were met with hard criticism. They were accepted only after some corrections were made.
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Histopathological findings from affected humans indicate that wound healing is impaired due to a deficiency in plasmin-mediated extracellular fibrinolysis. Episodes may be triggered by minor trauma, eye surgery, or by systemic events such as infections or antifibrinolytic therapy. Histology shows amorphous subepithelial deposits of eosinophilic material consisting predominantly of fibrin.
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Using these methods, after appropriate sample preparation, chemical biological tissue imaging analysis may be achieved.van Hove et al., 2010. From the end of the 1990s, it became apparent that mass spectrometry data in imaging studies showed a high degree of tissue specificity, that tissue histology could determine mass spectral information, and vice versa.
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The dentinoenamel junction or dentin-enamel junction (DEJ)A.Nanci. Ten Cate's Oral Histology: Development, Structure, and Function. 7th edition, Mosby, 2007, 432 p is the boundary between the enamel and the underlying dentin that form the solid architecture of a tooth. It is also known as the amelo-dentinal junction, or ADJ.
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Scylacops SAM-PK-10188 from the Iziko South African Museum has measurements as follows; Humerus 100 mm, Radii 83.25 mm, Ulna 99 mm, Femur 174.8 mm, Fibula, 96.67 mm Ray, Sanghamitra, Jennifer Botha & Anusuya Chinsamy. “Bone histology and growth patterns of some nonmammalian therapsids.” Journal of Vertebrate Paleontology, 24.3 (2004): 634-648..
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Extraskeletal myxoid chondrosarcoma (EMC) is a rare low-grade malignant mesenchymal neoplasm of the soft tissues, that differs from other sarcomas by unique histology and characteristic chromosomal translocation. There is an uncertain differentiation (there is no evidence yet showing that EMC exhibits the feature of cartilaginous differentiation) and neuroendocrine differentiation is even possible.
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Cross-sectional tomographic ultrasound (right) and optoacoustic (middle) whole-body image stacks of a living mouse. Histology cross-sections of the tissue shown on the left. E. Mercep, N.C. Burton, J. Claussen, D. Razansky, «Whole-body live mouse imaging by hybrid reflection-mode ultrasound and optoacoustic tomography», Opt Lett. 40 (2015)4643-4646.
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As a recognized leader in bone histology, he evaluates drafts regularly for several journals and serves on the editorial board (as Reviewing Editor) of the Comptes Rendus Palevol of the Académie des sciences (France). So far, his work has been cited more than 1561 times in scholarly works, according to Google Scholar.
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Verhoeff's stain, also known as Verhoeff's elastic stain (VEG) or Verhoeff–Van Gieson stain (VVG),Verhoeff-Van Gieson (VVG) Staining Protocol for Elastic Fibers. IHC World. URL: . Accessed on: January 2, 2013. is a staining protocol used in histology, developed by American ophthalmic surgeon and pathologist Frederick Herman Verhoeff (1874–1968) in 1908.
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At a gross anatomical level, this staged is marked by a yellow pallor. Weeks 1-3 are marked on histology by abundant capillaries, and fibroblast infiltration. Fibroblasts start replacing the lost cardiomyocytes with collagen type 1 and leads to the granulation of tissue. After several weeks fibrosis occurs and heavy collagen formation.
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The students of the school studied histology, anatomy, biology, physiology and their relation to orthodontics. In 1907, after the awarding of degrees of about 94 students in 8 years, the school was moved to New York City. Only one class graduated in that location. In 1908, the school moved to New London, Connecticut.
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Diktyoma, or ciliary body medulloepithelioma, or teratoneuroma, is a rare tumor arising from primitive medullary epithelium in the ciliary body of the eye. Almost all diktyomas arise in the ciliary body, although, rarely, they may arise from the optic nerve head or retina. The name "diktyoma" comes from its characteristic findings on histology.
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Condensed tannins can be characterised by a number of techniques including depolymerisation, asymmetric flow field flow fractionation or small-angle X-ray scattering. DMACA is a dye used for localization of procyanidin compounds in plant histology. The use of the reagent results in blue staining. It can also be used to titrate procyanidins.
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A graph showing the hypothesized growth curves (body mass versus age) of four tyrannosaurids. Daspletosaurus is shown in green, based on Erickson et al., 2004 Paleontologist Gregory Erickson and colleagues have studied the growth and life history of tyrannosaurids. Analysis of bone histology can determine the age of a specimen when it died.
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A graph showing the hypothesized growth curves (body mass versus age) of four tyrannosaurids. Gorgosaurus is shown in blue. Based on Erickson et al. 2004. Gregory Erickson and colleagues have studied the growth and life history of tyrannosaurids using bone histology, which can determine the age of a specimen when it died.
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Based on a skull length of 45 millimeters, Gobipteryx has been estimated to be approximately the size of a partridge.Elżanowski, A. (1976): Palaeognathous bird from the Cretaceous of Central Asia Nature 264: 51-53. Its bones are fibrolamellar.Chinsamy, A., Elżanowski, A. (2001): Bone histology: Evolution of growth pattern in birds Nature 412.
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Unspecific cortical lesion on CT scan is confirmed cystic and benign with contrast-enhanced renal ultrasonography. Most renal cell carcinomas are now found incidentally. Tumors less than 3 cm in diameter less frequently have aggressive histology. A CT scan is the first choice modality for workup of solid masses in the kidneys.
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Paraformaldehyde can be depolymerized to formaldehyde gas by dry heating and to formaldehyde solution by water in the presence of a base or heat. The high purity formaldehyde solutions obtained in this way are used as a fixative for microscopy and histology. The resulting formaldehyde gas from dry heating paraformaldehyde is flammable.
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The IFAA is the only international body representing all aspects of anatomy and anatomical associations. Since 1989 the Federative International Committee on Anatomical Terminology (FICAT) under IFAA auspices, has met to analyze and study the international morphological terminology (Anatomy, Histology and Embryology), releasing updated Terminologia Anatomica in 1998 and Terminologia Histologica in 2008.
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Sherrington ended up staying with Koch for a year to do research in bacteriology. Under these two, Sherrington parted with a good foundation in physiology, morphology, histology, and pathology. During this period he may have also studied with Waldeyer and Zuntz. In 1886, Sherrington went to Italy to again investigate a cholera outbreak.
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A team led by German paleontologist Florian Witzmann published a comparative histology study that sampled a number of dissorophids in 2010. May et al. (2011) described material of Aspidosaurus from the late Carboniferous of the mid-continent of North America. The first phylogenetic review of the Dissorophidae was published in 2012 by Schoch.
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This would support the hypothesis that these individuals represent either females or juveniles, where intra-specific combat behavior is not expected. Histological examination reveals that pachycephalosaurid domes are composed of a unique form of fibrolamellar boneReid REH (1997) "Histology of bones and teeth." In: Currie, PJ and Padian, K, editors. Encyclopedia of Dinosaurs.
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Crețu, p. 135 He studied natural sciences at the German University in Prague. In 1897, he became a teaching assistant at its zoology institute; a year later, he received a doctorate. From 1898 to 1919 he taught natural sciences at the normal school in Czernowitz, paying particular attention to students from rural backgrounds like himself. In 1907, he became assistant professor of histology at Czernowitz University, and also performed laboratory research on the comparative anatomy and histology of sensory organs in vertebrates. In 1913, upon being nominated by Ion Th. Simionescu, he was elected a corresponding member of the Romanian Academy.Crețu, p. 136 During World War I, when the local schools were closed due to the Russian occupation, he taught at the high school in Rădăuți.
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After attending the Faculty of Medicine of Bucharest University, Marinescu received most of his medical education as preparator at the laboratory of histology at the Brâncoveanu Hospital and as assistant at the Bacteriological Institute under Victor Babeş, who had already published several works on myelitis transversa, hysterical muteness, and dilatation of the pupil in pneumonia.
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Based on several studies, the many-banded krait is among the most venomous land snakes in the world. α-Bungarotoxin is important for neuromuscular histology, it is known to bind irreversibly to receptors of the neuromuscular junction, and can be labelled with fluorescent proteins such as green fluorescent protein or the rhodamine dye tetramethylrhodamine isothiocyanate.
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Capsule endoscopy (CE) allows identification of typical mucosal changes observed in coeliac disease but has a lower sensitivity compared to regular endoscopy and histology. CE is therefore not the primary diagnostic tool for coeliac disease. However, CE can be used for diagnosing T-cell lymphoma, ulcerative jejunoileitis and adenocarcinoma in refractory or complicated coeliac disease.
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External lamina is a structure similar to basal lamina that surrounds the sarcolemma of muscle cells. It is secreted by myocytes and consists primarily of Collagen type IV, laminin and perlecan (heparan sulfate proteoglycan). Nerve cells, including perineurial cells and Schwann cells also have an external lamina-like protective coating.Wheater's Functional Histology, 5th ed.
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They had a son Johan Schreiner, and through another son Fredrik Schreiner they had the grandson Per Schreiner. He took his examen artium in 1892 and graduated with the cand.med. degree in 1899. He then studied histology, embryology and cytology for one year in Würzburg, one year in Prague and half a year in Liège.
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Janků (1923) described in detail the autopsy results of an 11-month-old boy who had presented to hospital with hydrocephalus. The boy had classic marks of toxoplasmosis including chorioretinitis (inflammation of the choroid and retina of the eye). Histology revealed a number of "sporocytes", though Janků did not identify these as T. gondii.
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Studying physiology and histology at Halle University in Germany and Head was soon proficient in the German language. Later in his life, Head would be repeatedly mistaken for a German at frontier posts due both to his aptitude for the language and his markedly Germanic physical appearance.Sir Henry Head. Whonamedit.com. Retrieved on 1 June 2014.
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Class I disease (minimal mesangial glomerulonephritis) in its histology has a normal appearance under a light microscope, but mesangial deposits are visible under an electron microscope. At this stage urinalysis is normal. Class II disease (mesangial proliferative glomerulonephritis) is noted by mesangial hypercellularity and matrix expansion. Microscopic haematuria with or without proteinuria may be seen.
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The stress and strain resistance provided by CCCB allows aardvarks to create their burrows, ultimately leading to a favorable environment for plants and a variety of animals.Botha-Brink, J., & Legendre, J. L. (2018). Digging the compromise: investigating the link between limb and bone histology and fossoriality in the aardvark (Orycteropus afer). PeerJ, 6, 1-40.
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Noyes joined the University of Illinois at Chicago College of Dentistry as professor and head of the Department of Dental Histology in 1913 and became dean of the College in 1924. He was known for his willingness to experiment with change and innovation in the curriculum. Noyes served as dean of the College until 1940.
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This has future applications for monitoring glaucoma patients who either have changes in nerve fiber layer thickness or alterations in vasculature from damage to the retina.Scoles D, Gray DC, Hunter JJ, Wolfe R, Gee BP, Geng Y, et al. "In vivo imaging of retinal nerve fiber layer vasculature: imaging histology comparison". BMC Ophthalmol. 2009;9:9.
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Acid fuchsin or fuchsine acid, (also called Acid Violet 19 and C.I. 42685) is an acidic magenta dye with the chemical formula C20H17N3Na2O9S3. Acid fuchsin has wide use in histology, and is one of the dyes used in Masson's trichrome stain.Jocelyn H. Bruce-Gregorios, M.D.: Histopathologic Techniques, JMC Press Inc., Quezon City, Philippines, 1974.
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The forelimbs were longer than the hindlimbs, in contrast to the more derived sauropods. It has been calculated around 9-10 m long.Redelstorff, R. A. G. N. A., Sander, P. M., & Galtom, P. M. (2013). Unique bone histology in partial large bone shafts from Aust Cliff (England, Upper Triassic): an early independent experiment in gigantism.
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Histology shows a change in the prickle cell layer, and this is responsible for the laying down of condensed keratin causing the groove. The junctional tissue is reduced to a slender fibrous thread, almost avascular, and all the tissues beyond the constricting band is repressed by a fibro-fatty mass covered by hyperkeratotic integument.
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The brain histology of viral encephalitis shows dead neurons with nuclear dissolution and elevated eosinophil count, called hypereosinophilia, within cells' cytoplasm when viewed with an optical microscope. Because encephalitis is an inflammatory response, inflammatory cells situated near blood vessels, such as microglia, macrophages, and lymphocytes, are visible. Virions within neurons are visible via electron microscopes.
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Results correlated well with conventional smears and follow-up histology. Another method described by Johnson et al. (2000) places the cervical collection device into 15 ml of CytoRich Red (TriPath Imaging), a proprietary formula of buffering agents, emulsifiers, formaldehyde, and alcohol. After arrival in the laboratory, cell suspensions are vortexed, poured through tulle and centrifuged.
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This property can be used to accurately determine the amount of water in a sample, alternatively to Karl Fischer method. DMP is specifically used to prepare acetonides: :RCHOHCHOHCH2 \+ (MeO)2CMe2 → RCHCHCH2O2CMe2 \+ 2 MeOH Dimethoxypropane is an intermediate for the synthesis of 2-methoxypropene. In histology, DMP is used for the dehydration of animal tissue.
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Aside from his medical research, Dr. Kochaji has enriched the library of the Arab medical researcher by translating some key references. Notably, Ten Car`s Oral Histology, Forensic Dental Evidence, second edition (Bilingual Book, English- Arabic),Cawson`s Essentials of Oral Pathology and Medicine, Forensic Dental Evidence all in co-publishing program with ELSEVIER publishers.
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Along with practicing, he was also the Professor of Histology at Quincy College of Medicine. Dr. Gilmer then moved to Chicago in 1889 where he was a professor of Oral Surgery at the Chicago College of Dental Surgery. In 1891, he founded the Northwestern University Dental School. Dr. Gilmer served as a dean of the school eventually.
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If the site of origin is unknown or undiscovered, then the histology of the tumor (e.g., adenocarcinoma, squamous cell or mesenchymal) can usually be identified, and a probable origin may be assumed. When this is possible, then treatment is based on the type of cell and probable origin. Based on histological subtype, combination chemotherapy may be selected.
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In 1947-1948, he received a scholarship to further study electron microscopy at Massachusetts Institute of Technology's Department of Biology. Back in Sweden, he received funding to build up an electron microscopy research laboratory. In 1959, Sjöstrand was both offered a position as professor of histology at Karolinska Institutet, and as professor at University of California, Los Angeles (UCLA).
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Condensed tannins may be characterised by a number of techniques including depolymerisation, asymmetric flow field flow fractionation or small-angle X-ray scattering. DMACA is a dye that is particularly useful for localization of proanthocyanidin compounds in plant histology. The use of the reagent results in blue staining. It can also be used to titrate proanthocyanidins.
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Other aspects of the biology of this species have been well- studied, from the production and morphologyTeixeira, R.D., et al. (1999). Ultrastructural study of the spermatozoa of the Neotropical lizards, Tropidurus semitaeniatus and Tropidurus torquatus (Squamata, Tropiduridae). Tissue & Cell 31 (3): 308-317. of its spermatozoa, to the histology of its liver,Firmiano, E.M.S., et al. (2011).
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In addition to its natural-history collections, the Museum of Zoology has a library and laboratories dedicated to chronobiology, electron microscopy, molecular biology, histology and CT-scans. Its library has one of the most complete zoological collections in South America: over 248,000 volumes (including books, theses and dissertations), scientific journals, specialized magazines, maps, and electronic information- storage media.
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He then served as department head of the Laboratory of Reproductive Biology and Cytogenetics Laboratory, studying quantitative cytology and histology at the teaching hospital of Strasbourg. From 1980 to 2007 Yves Rumpler taught at the Institute of Embryology in the University of Strasbourg. He has received an honorary doctorate from the Ruhr University of Bochum, Germany.
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Histopathology is the branch of histology that includes the microscopic identification and study of diseased tissue. It is an important part of anatomical pathology and surgical pathology, as accurate diagnosis of cancer and other diseases often requires histopathological examination of tissue samples. Trained physicians, frequently licensed pathologists, perform histopathological examination and provide diagnostic information based on their observations.
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The Allied Health Division offered degrees in cardiovascular technology, dental hygiene, diagnostic medical sonography, emergency medical services, health information technology, medical laboratory technology, histology technology, medical laboratory technology, occupational therapy assistant, physical therapy assistant, and respiratory care. In addition, certificates were offered in accelerated polysomnography, emergency medical services, histotechnology, medical billing and coding, and medical transcription.
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This appears to have been an adaptation to predation pressures, as large eggs would require greater incubation time and thus would be at greater risk. Based on a number of bone histology studies, Diplodocus, along with other sauropods, grew at a very fast rate, reaching sexual maturity at just over a decade, and continued to grow throughout their lives.
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Histology of ciliated columnar epithelium of the fallopian tube. The innermost layer of the tube is an epithelium composed of a single layer of column-shaped cells. The columnar cells have microscopic hair- like filaments called cilia throughout the tube, most numerous in the infundibulum and ampulla. Estrogen increases the formation of cilia on these cells.
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Gardner taught pathology, toxicology, physiology, histology, and chemistry at the University of Southern California.University of Southern California, Circular of Information (1909): 156, 165, 194. She was also on staff at Los Feliz Hospital. In January 1917 she was appointed to the office of City Bacteriologist"Woman is Appointed City Bacteriologist" Los Angeles Daily Times (January 4, 1917): 13.
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This may be difficult given the non specific nature of the presenting symptoms and the rarity of the condition itself. It is normally made by the combination of the clinical picture, endoscopic findings and typical histology. Radiology may also be helpful. Other conditions such as infections and vasculitis should be ruled out with the relevant laboratory investigations.
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Microscopic view of a histologic specimen of human lung tissue stained with hematoxylin and eosin. Haematoxylin and eosin staining is frequently used in histology to examine thin tissue sections. Haematoxylin stains cell nuclei blue, while eosin stains cytoplasm, connective tissue and other extracellular substances pink or red. Eosin is strongly absorbed by red blood cells, colouring them bright red.
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There are no specific laboratory findings associated with this condition, and the histology tends to be similar to that seen in rosacea. The differential diagnosis includes acne vulgaris, streptococcal cellulitis, and Melkersson–Rosenthal syndrome, as these conditions can also rarely manifest with a similar edema, as well as other forms of rosacea, lupus erythematosus, and sarcoidosis.
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A gonadal tissue neoplasm is a tumor having any histology characteristic of cells or tissues giving rise to the gonads. These tissues arise from the sex cord and stromal cells. The tumor may be derived from these tissues, or produce them. Although the tumor is composed of gonadal tissue, it is not necessarily located in an ovary or testicle.
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The Terminologia Histologica (TH) is the controlled vocabulary for use in cytology and histology. In April 2011, Terminologia Histologica was published online by the Federative International Programme on Anatomical Terminologies (FIPAT), the successor of FCAT. It was intended to replace Nomina Histologica. The Nomina Histologica was introduced in 1977, with the fourth edition of Nomina Anatomica.
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Genetic testing should be considered with adrenocortical carcinoma; carcinoid tumors; diffuse gastric cancer; fallopian tube/primary peritoneal cancer; leiomyosarcoma; medullary thyroid cancer; paraganglioma/pheochromocytoma; renal cell carcinoma of chromophobe, hybrid oncocytic, or oncocytoma histology; sebaceous carcinoma; and sex cord tumors with annular tubules. Primary care physicians can identify people who are at risk of heridatary cancer syndrome.
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Causes are not known. The histology is suggestive of an autoimmune reaction. The high rate of relapses as well as relatively high proportion of bilateral cases is highly suggestive of a systemic predisposition. Presently most evidence points towards an important role of elevated prolactin levels or overt hyperprolactinemia with additional triggers such as local trauma or irritation.
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They are associated with human papillomavirus, the causative agent of genital warts. The lesions have a typical dysplastic histology and are generally considered benign, although a small percentage will develop malignant characteristics. It is considered as a pre-malignant condition. Other terms used to describe the condition are: Erythroplasia of Queyrat, Squamous cell carcinoma in situ and Bowen's disease.
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A graph showing the hypothesized growth curves (body mass versus age) of four tyrannosaurids. Gorgosaurus is shown in blue and Albertosaurus is shown as red. Based on Erickson et al. 2004. Gregory Erickson and colleagues have studied the growth and life history of tyrannosaurids using bone histology, which can determine the age of a specimen when it died.
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Occurring only in adult humans and wild bush rats, their function is unknown.Young, Barbara; Woodford, Phillip; O'Dowd, Geraldine. Wheater's Functional Histology: A Text and Colour Atlas (2014), Sixth Edition, Elsevier, Philadelphia, p. 344. Ovarian stromal tumors having a predominant pattern of fibroma or thecoma but also containing cells typical of steroid hormone-secreting cells were reported.
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Cryostat-microtome Cryostat are used in medicine to cut histological slides. They are usually used in a process called frozen section histology (see Frozen section procedure). The cryostat is essentially an ultrafine "deli-slicer", called a microtome, placed in a freezer. The cryostat is usually a stationary upright freezer, with an external wheel for rotating the microtome.
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Veit Krenn spent his childhood partially in Florida but mostly in Vienna. He earned his Dr. med. univ. at the Medical University of Vienna on November 30, 1987 with his work about Migration und Determination myogener Zellen im Embryo. From 1988 to 1992 he worked as a medical intern at the Institute of Histology and Embryology in Vienna.
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During the 19th century, anatomical research was extended with histology and developmental biology of both humans and animals. Women, who were not allowed to attend medical school, could attend the anatomy theatres. From 1822 the Royal College of Surgeons forced unregulated schools to close. Medical museums provided examples in comparative anatomy, and were often used in teaching.
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A rhabdomyoblast is a cell type which is essential to the diagnosis of a rhabdomyosarcoma. A rhabdomyoblast found histologically is considered diagnostic for embryonal, alveolar, and pleomorphic rhabdomyosarcomas. Histology will show an elongated or round cell, exhibiting an embryonic morphology. Occasionally cells will exhibit cross striations by light microscopy, reflecting sarcomere formation and advancement of differentiation.
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Safranin (also Safranin O or basic red 2) is a biological stain used in histology and cytology. Safranin is used as a counterstain in some staining protocols, colouring cell nuclei red. This is the classic counterstain in both Gram stains and endospore staining. It can also be used for the detection of cartilage, mucin and mast cell granules.
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Paluh et al. studied the osteoderm of Geckolepis cf. maculata using micro-CT and histology, and compared it to other geckos known to have osteoderm, namely Gekko gecko and Tarentola mauritanica. They found that the osteoderms differ strongly from those of the other gecko species that possess them, and represent a third independent convergent derivation of osteoderm in geckos.
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The school comprises 10 Academic departments including Anatomy, Histology, Biochemistry, Physiology, Pharmacology, Pathology, Parasitology, Microbiology, Community Medicine (Community, Environmental & Occupational Medicine), Forensic and Toxicology. All of the 21 clinical departments are located in the University hospitals, including the 6 major Clinical departments (Ophthalmology, Ear, Nose and Throat (ENT), Internal medicine, Tropical medicine, Surgery, Obstetrics & Gynecology and Pediatrics).
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Sample of a trachea coloured with hematoxylin and eosin. Eosin is most often used as a counterstain to hematoxylin in H&E; (haematoxylin and eosin) staining. H&E; staining is one of the most commonly used techniques in histology. Tissue stained with haematoxylin and eosin shows cytoplasm stained pink-orange and nuclei stained darkly, either blue or purple.
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This type was recognised by the WHO in 2010 and constitutes about 1–3% of all pancreatic neoplasms. Mean age at diagnosis is 61 years (range 35–78 years). About 50% of these lesions become invasive. Diagnosis depends on histology, as these lesions are very difficult to differentiate from other lesions on either clinical or radiological grounds.
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This method is commonly used to stain cytoplasm and nuclei of tissue sections in the histology laboratory in order to distinguish muscle from collagen. The muscle stains red with the acid fuchsin, and the collagen is stained green or blue with Light Green SF yellowish or methyl blue. It can also be used to identify growing bacteria.
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The term parenchyma is New Latin from the Greek word παρέγχυμα parenchyma 'visceral flesh' from παρεγχεῖν parenkhein 'to pour in' from παρα- para- 'beside' + ἐν en- 'in' + χεῖν khein 'to pour'. Originally, Erasistratus and other anatomists used it to refer to certain human tissues.Virchow, R.L.K. (1863). Cellular pathology as based upon physiological and pathological histology [...] by Rudolf Virchow.
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K. Padian, A. J. de Ricqles, and J. R. Horner. 1995. Bone histology determines identification of a new fossil taxon of pterosaur (Reptilia: Archosauria). Comptes Rendus de l’Academie des Science, Serie II (320)77-84 The material, a partial skull, was recovered from channel sandstone sediments that were deposited during the Campanian stage, approximately 74 million years ago.
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The study of the human body involves anatomy, physiology, histology and embryology. The body varies anatomically in known ways. Physiology focuses on the systems and organs of the human body and their functions. Many systems and mechanisms interact in order to maintain homeostasis, with safe levels of substances such as sugar and oxygen in the blood.
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Ponceau 6R, or Crystal ponceau 6R, Crystal scarlet, Brilliant crystal scarlet 6R, Acid Red 44, or C.I. 16250, is a red azo dye. It is soluble in water and slightly soluble in ethanol. It is used as a food dye, with E number E126. It is also used in histology, for staining fibrin with the MSB Trichrome stain.
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Black and white microphotograph of Feulgen stained, intact tick salivary glands infected by deer tick virus. Hypotrophied salivary acinus filled with amorphous masses of pinkstaining (=Feulgen positive) material (arrows). Scale bar = 10 µm. Feulgen stain is a staining technique discovered by Robert Feulgen and used in histology to identify chromosomal material or DNA in cell specimens.
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Frederik Vilhelm August Meinert (1833, in Copenhagen – 1912), was a Danish entomologist and editor of the first series of Entomologiske Meddelelser. Meinert initially studied theology . Later he was a pupil of Jørgen Matthias Christian Schiødte and he too became Inspektor at the Zoological Museum in Copenhagen. Meinert specialised in comparative anatotomy and histology mainly of Malacostraca and Pycnogonida .
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Bismarck brown Y also called C.I. 21000 and C.I. Basic Brown 1, is a diazo dye with the idealized formula [(H2N)2C6H3N2]2C6H4. The dye is a mixture of closely related compounds. It was one of the earliest azo dyes, being described in 1863 by German chemist Carl Alexander von Martius. It is used in histology for staining tissues.
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The outbreak of the Second World War restricted access to materials for sculpture. He became a member of the British Bryological Society, and prepared hundreds of illustrations for A Histology of British Mosses. He died on 8 May 1955. He is commemorated in the naming of a public house, The Joseph Else, at 11-12 South Parade, Nottingham.
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The palatine uvula, usually referred to as simply the uvula, is a conic projection from the back edge of the middle of the soft palate, composed of connective tissue containing a number of racemose glands, and some muscular fibers.Ten Cate's Oral Histology, Nanci, Elsevier, 2007, page 321 It also contains many serous glands, which produce thin saliva.
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Pagel: Biographical Dictionary excellent doctors of the nineteenth century. Berlin, Vienna, 1901, col 325-326. In the fields of anatomy and histology, he is known for studies involving the finer structure of the eye (microscopic investigations of the conjunctiva, cornea and vitreous). He also made contributions involving research of peripheral nerve fiber terminations in vertebrates (e.g.
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Simon Henry Gage (May 20, 1851 - October 20, 1944) was a Professor of Anatomy, Histology, and Embryology at Cornell University and an important figure in the history of American microscopy. His book, The Microscope, appeared in seventeen editions. In 1931, a volume of the American Journal of Anatomy was dedicated to Gage on the occasion of his eightieth birthday.
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Again, this term proved to be incorrect since the papules were neither adenoma nor derived from sebaceous glands. Between 1880 and 1887, Balzer was a director of the histology laboratory in the Faculty of the hospital Saint Louis. He became a member of the Académie de Médecine in 1908. He was also president of la Société Française de Dermatologie.
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PNET has five subtypes of tumors: neuroblastoma, ganglioneuroblastoma, medulloepithelioma, ependymoblastoma, and not otherwise specified PNET. It is similar to medulloblastoma regarding histology but different regarding genetic factors and tumor site. It is a rare disease occurring mostly among children, accounting for 1.9 to 7% of childhood brain tumors. Symptoms involve emotional, visual, motor, and speech defects.
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Some of his well-known students were Heinrich Auspitz (1834-1885), Moritz Kaposi (1837-1902) and Salomon Stricker (1834-1898). Wedl is largely remembered for his work in microscopic pathology and histology. He made contributions in the fields of helminthology, neurology and ophthalmology, and was one of the first physicians to apply cell theory to pathology of the eye.
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The skin creases of the human body are features of great anatomical, morphological, and surgical interest and important for the maintenance of the contour of each anatomic area. In the literature, when referring to a skin crease, there is variation of terms used other than "crease", such as "fold" and "sulcus", but these terms do not accurately reflect their histology structure nor their function. In the review of literature, a record of the creases of the human body for each anatomic area, including the synonyms that are used for each crease in the literature, has been attempted. The skin crease as a fixed and permanent line, according to their histology, is related to connective tissue attachments with the underlying structures or extensions of the underlying muscle fibers in the dermis of the crease site.
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Sherrington said: > "after some hundreds of years of experience we think that we have learned > here in Oxford how to teach what is known. But now with the undeniable > upsurge of scientific research, we cannot continue to rely on the mere fact > that we have learned how to teach what is known. We must learn to teach the > best attitude to what is not yet known. This also may take centuries to > acquire but we cannot escape this new challenge, nor do we want to." Box of microscope slides carrying the plaque:"Sir Charles Sherrington's Histology Demonstration Slides: St Thomas's Hospital: 1886–1895; Liverpool University: 1895–1915; Oxford University: 1914–1935" While at Oxford, Sherrington kept hundreds of microscope slides in a specially constructed box labelled "Sir Charles Sherrington's Histology Demonstration Slides".
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Two well-known island dwarf species of sauropods are the Cretaceous Magyarosaurus (at one point its identity as a dwarf was challenged) and the Jurassic Europasaurus, both from Europe. Even though these sauropods are small, the only way to prove they are true dwarfs is through a study of their bone histology. A study by Martin Sander and colleagues in 2006 examined eleven individuals of Europasaurus holgeri using bone histology and demonstrated that the small island species evolved through a decrease in the growth rate of long bones as compared to rates of growth in ancestral species on the mainland. Two other possible dwarfs are Rapetosaurus, which existed on the island of Madagascar, an isolated island in the Cretaceous, and Ampelosaurus, a titanosaur that lived on the Iberian peninsula of southern Spain and France.
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Histology of compact bone showing osteon Each osteon consists of concentric layers, or lamellae, of compact bone tissue that surround a central canal, the haversian canal. The haversian canal contains the bone's blood supplies. The boundary of an osteon is the cement line. Each haversian canal is surrounded by varying number (5-20) of concentrically arranged lamellae of bone matrix.
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Glioma 261 (GL261) is a frequently used murine glioma model. It was induced via intracranial injection of methylcholanthrene followed by serial intracranial and subcutaneous transplantations of tumor fragments into syngeneic C57BL/6 mice. By the mid-1990s, multiple groups had established a permanent cell line from the tumor. GL261 tumors resemble ependymoblastomas on histology but show many characteristics of glioblastoma phenotypes.
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The microscopic examination of tissue (histology) gives the definitive diagnosis. The diagnostic histopathologic finding is intravascular cholesterol crystals, which are seen as cholesterol clefts in routinely processed tissue (embedded in paraffin wax). The cholesterol crystals may be associated with macrophages, including giant cells, and eosinophils. The sensitivity of small core biopsies is modest, due to sampling error, as the process is often patchy.
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Of the 264 scientific publications in his career nearly 200 were in microbiology. Ronald Ross was one of Klein's students. Klein was the author of the Elements of Histology (1883). His name was originally just Emanuel and he signed as E.Klein but during his membership with the Organon Club (founded by Ray Lankester) the secretary thought it stood for Edward.
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Organs are then formed by the functional grouping together of multiple tissues. The English word "tissue" derives from the French word "tissu", meaning that something that is "woven", from the verb tisser, "to weave". The study of human and animal tissues is known as histology or, in connection with disease, as histopathology. For plants, the discipline is called plant anatomy.
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Edward Charles Jeffrey (May 21, 1866 – April 19, 1952) was a Canadian-American botanist who worked on vascular plant anatomy and phylogeny. From 1892 to 1902 Jeffrey was a lecturer at the University of Toronto. While on leave of absence, he received his Ph.D. from Harvard University in 1899. In 1902 he became there an assistant professor of vegetable histology.
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It has four lecture galleries equipped with all modern teaching aids (of which two gallery is air conditioned). It has a dissection hall with attached preservation room, has a histology room and has a museum for the department of Anatomy. In addition it has well furnished laboratories for all other pre- clinical & para-clinical departments. Every departments have their own tutorial room.
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It has enough histology slides, cadavers, viscera and models in the department of Anatomy. Ward placement for the clinical years are held in Chittagong CMH. Medicine & Surgery ward of Chittagong CMH are now affiliated by BCPS and affiliation of BCPS for Gynae & Obstetrics ward, Eye & ENT ward are under process. Autopsy classes are held in Chittagong Medical College under special considerations.
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Shepherd was born in 1934 in New South Wales, Australia. She studied anatomy, physiotherapy, histology, chemistry and physics at the University of Sydney, graduating in 1956 with a Diploma of Physiotherapy. After winning a Fulbright Fellowship for doctoral study, she went to Columbia University, studying under Ann Gentile. There she received degrees, Master of Arts in 1986 and Doctor of Education in 1991.
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He studied medicine in Paris, earning his doctorate in 1864. In 1869 he became professeur agrègé to the Paris faculty, and in 1884 a member of the Académie Nationale de Médecine. Cornil was elected a member of the Royal Swedish Academy of Sciences in 1902. Cornil specialized in pathological anatomy, and made important contributions in the fields of bacteriology, histology and microscopic anatomy.
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Cerament is a synthetic, injectable, osteoconductive biomaterial, which actively promotes bone healing and is utilized as a bone substitute, when bone grafting is needed. Full remodeling to healthy bone occurs between 6 and 12 months.Bone Healing Using a Bi-Phasic Ceramic Bone Substitute Demonstrated in Human Vertebroplasty and with Histology in a Rabbit Cancellous Bone Defect Model. H.P. Hatten Jr, J. Voor.
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Bouin solution is a common picric- acid-containing fixative solution used for histology specimens. It improves the staining of acid dyes, but it can also result in hydrolysis of any DNA in the sample. Clinical chemistry laboratory testing utilizes picric acid for the Jaffe reaction to test for creatinine. It forms a colored complex that can be measured using spectroscopy.
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Histology of the endocardium and subendocardium. The endocardium, which is primarily made up of endothelial cells, controls myocardial function. This modulating role is separate from the homeometric and heterometric regulatory mechanisms that control myocardial contractility. Moreover, the endothelium of the myocardial (heart muscle) capillaries, which is also closely appositioned to the cardiomyocytes (heart muscle cells), is involved in this modulatory role.
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Mărghitan & Mancaș, p. 46 In 1903, with Alexandru Popovici and Leon Cosmovici, he held a pioneering extracurricular course on parasitology."Ultime informațiunĭ", in Adevărul, November 19, 1903, p. 5 He then followed up with other such courses, in embryology and histology. From 1904, his articles promoting physical culture among the peasantry were hosted by Cultura Română, the popular pedagogy magazine,D.
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In 1937, W. Cramer experimentally showed that Fibiger's tumour were not cancerous. The final disproof was shown by Claude R. Hitchcock and E. T. Bell. In 1952, they repeated Fibiger's experiments using advanced microscopy and histology, and conclusively demonstrated that the tumours due to G. Neoplasticum in rats were non-cancerous tumours. And the tumours were primarily due to vitamin A deficiency.
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He continued to work as a lecturer and researched on aspects of comparative zoology, anatomy and histology under Karl Bogislaus Reichert leading to being appointed Professor in 1873. He also worked with Friedrich Theodor von Frerichs. At the same time he was offered the Chair of Anatomy in Tokyo. He left Germany on 10 July 1873 for Japan after marrying Martha Schirmeister.
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Blue coloured elastic fibers Weigert's elastic stain is a combination of stains used in histology which is useful in identifying elastic fibers. Often orcein or a combination of resorcinol and fuchsine are used for staining. For counterstaining cell nuclei nuclear fast red or hematoxylin is also used. After applying elastic fibers show up blue coloured while cell nuclei gets red or blue.
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These intervening histologic regions have been referred to as the middle segment. The histologic regions of the middle segment (Figure 1C) can vary in number in metatherianOrsi, M.A., Ferreira, A.L., de Melo, V.R. & Oliveira, M.C. (1981). Regional histology of the epididymis in the South American opossum. Light microscopic study. Anatomischer Anzeiger 150: 521-528.Cummins, J.M., Temple-Smith, P.D. & Renfree, M.B. (1986).
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Most often, a urologist or radiologist will remove a cylindrical sample (biopsy) of prostate tissue through the rectum (or, sometimes the perineum), using hollow needles, and biomedical scientists in a histology laboratory prepare microscope slides for H&E; staining and immunohistochemistry for diagnosis by a pathologist. If the prostate is surgically removed, a pathologist will slice the prostate for a final examination.
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In 2013, a study by Ragna Redelstorff e.a. concluded that the bone histology of Kentrosaurus indicated that it had a higher growth rate than reported for Stegosaurus and Scutellosaurus, in view of the relatively rapid deposition of highly vascularised fibrolamellar bone. As Stegosaurus was larger than Kentrosaurus, this contradicts the general rule that larger dinosaurs grew quicker than smaller ones.
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The appearance of the tissue formed in this process looks normal by histology (a method used by pathologists to determine the presence of cancer cells). However, Shachaf showed that the cells derived from the tumor are "camouflaged" to appear normal but have the capability to easily revert and become tumors.Shachaf CM. and Felsher D. W. Rehabilitation of cancer through oncogene inactivation.
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He then entered the Bland-Sutton Institute of Pathology under the directorship of James McIntosh. Here he assisted S. L. Baker in the Department of Morbid Pathology and Histology. When Baker went to Manchester in 1931 Scarff replaced him as head of Department. The role necessitated further study to obtain a full medical degree and he then qualified MB BSc.
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William Heaton Horrocks was the son of William Holden Horrocks of Bolton. Horrocks studied for his M.B. at Owen's College and passed his first M.B. examination in 1881. He received a Third Class Honours pass in Anatomy, and a Second Class in Physiology and Histology. Previously a Surgeon on probation, Horrocks was promoted to Surgeon (the equivalent of Captain) on 5 February 1887.
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The liver histology shows microvesicular steatosis and cholestasis with abundant iron accumulation in hepatocytes and Kupffer cells. The liver iron content slightly decreases with age, concomitantly with increasing liver fibrosis and cirrhosis. Abnormal transaminases and coagulation are noted. There are currently a combination of 55 biochemical and molecular genetics tests that can be completed prior to birth to diagnose GRACILE syndrome.
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Geoffrey Howard Bourne (17 November 1909 – 19 July 1988) was an Australian- American anatomist and primatologist. In particular, he studied the adrenal gland, conducting pioneering work in histochemistry. Bourne was director of Yerkes National Primate Research Center at Emory University from 1962 until 1978. Prior to coming to Emory he had taught histology at the University of London and physiology at Oxford University.
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Facilities include the Stanley Law Library, the general library, the Gibson Room for biomedical studies (anatomy and histology, speech therapy and physiotherapy). In the gymnasium there is also a squash court, weights room, and sauna (sometimes), as well was pool and ping- pong tables. All undergraduate students also have access to the Junior Common Room. St John's College has a strong social atmosphere.
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Sebum is produced in a holocrine process, in which cells within the sebaceous gland rupture and disintegrate as they release the sebum and the cell remnants are secreted together with the sebum.Victor Eroschenko, diFiore's Atlas of Histology with functional correlations, Lippincott Williams & Wilkins, 10th edition, 2005. p. 41 The cells are constantly replaced by mitosis at the base of the duct.
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The diagnosis of THRLBCL, particularly as it pertains to differentiating it from DLBCL and other lymphomas, depends on examining involved tissues obtained by biopsy or operation for their histology, i.e. microscopic anatomy. The tissues involved in THRLBCL commonly show an effacement of their normal architecture by a diffusely growing infiltrate of non-malignant T-cell lymphocytes, histiocytes, and neoplastic (i.e. malignant) B-cells.
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Rodents have upper and lower hypselodont incisors that can continuously grow enamel throughout its life without having properly formed roots. These teeth are also known as aradicular teeth, and unlike humans whose ameloblasts die after tooth development, rodents continually produce enamel, they must wear down their teeth by gnawing on various materials.Caceci, Thomas. Veterinary Histology with subtitle "Digestive System: Oral Cavity" found here .
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In 1888 Hernández graduated as a medical doctor at Universidad Central de Venezuela, in Caracas. The Venezuelan government awarded him a grant to continue his studies in Europe. Hernández traveled to Paris, where he studied other fields of medicine such as: bacteriology, pathology, microbiology, histology, and physiology. Following his return to Venezuela, he became a leading doctor at the Hospital José María Vargas.
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The histology of spontaneous tumorigenesis in canines is attributed to the multiplicity and complexity of the disease. The heterogeneity of its development encompasses inherited, epigenetic, and environmental factors. The selective breeding techniques used with domestic dogs causes certain breeds to be at high risk for specific cancers. Selection for specific phenotypes in dog breeding causes long-range linkage disequilibrium in their DNA.
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Río Hortega was born in Portillo, Valladolid on 5 May 1882. He studied locally and qualified to practice medicine in 1905. He obtained his doctorate at the University of Madrid by researching the pathology of brain tumours. In 1913, he was funded to study research histology in France and Germany but the outbreak of war between them forced him to return to Spain.
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The tusks are surrounded posteriorly, ventrally, and laterally by several small vestigial teeth which vary in morphology and histology. These teeth can sometimes be extruded from the bone, but mainly reside inside open tooth sockets in the narwhal's snout alongside the tusks. The varied morphology and anatomy of small teeth indicate a path of evolutionary obsolescence, leaving the narwhal's mouth toothless.
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It is used in histology for staining collagen; for that purpose it is a standard dye in North America. In Masson's trichrome it is used as a counterstain to acid fuchsin. It is a component of Papanicolaou stains together with eosin Y and bismarck brown Y. It usually comes as a disodium salt. Its maximum absorption is at 630 (422) nm.
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There are multi-nucleated giant cells on histology. Thyroid antibodies can be present in some cases. The clinical presentation during the hyperthyroid phase can mimic those of Diffuse Toxic Goiter or Graves' disease. In such cases, a radionuclide thyroid uptake and scan can be helpful, since subacute thyroiditis will result in decreased isotope uptake, while Graves' disease will generally result in increased uptake.
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Haematoxylum campechianum was used for a long time as a natural source of dye. The woodchips are still used as an important source of haematoxylin, which is used in histology for staining. The bark and leaves are also used in various medical applications. In its time, it was considered a versatile dye, and was widely used on textiles and also for paper.
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A liver biopsy stained using the grocott's methenamine silver stain demonstrating histoplasma (black round balls) in a granuloma. In pathology, the Grocott-Gomori's (or Gömöri) methenamine silver stain, abbreviated GMS, is a popular staining method in histology. The stain was originally named after György Gömöri, the Hungarian physician who developed the stain. It is used widely as a screen for fungal organisms.
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Type I: DI associated with Osteogenesis Imperfecta (OI). Type of DI with similar dental abnormalities usually an autosomal dominant trait with variable expressivity but can be recessive if the associated osteogenesis imperfecta is of recessive type.Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 15 Type II: DI not associated with OI. Occurs in people without other inherited disorders (i.e. Osteogenesis imperfecta).
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The results of pioneering efforts to age dinosaur fossils using growth ring counts suggest that the longevity of the basal ceratopsian Psittacosaurus mongoliensis was 10 or 11 years.Erickson, G. M. and Tumanova, T. A. (2000). Growth curve and life history attributes of Psittacosaurus mongoliensis (Ceratopsia: Psittacosauridae) inferred from long bone histology. Zoological Journal of the Linnean Society. 130:551-566.
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In the family Linophrynidae, males are obligatory sexual parasites.Munk, O, Bertelsen, E, Histology of the attachment between the parasitic male and the female in the deep-sea anglerfish Haplophryne mollis (Brauer, 1902) (Pisces, Ceratioidei). Vidensk. Meddr. Dansk Naturh. Foren., 144: 49-74, 1983 Attached males are nearly always found upside down, facing forward, and attached to the belly close to the anus.
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After graduation, MacArthur was an Assistant Professor of Botany at a woman's college in Elmira, New York, from 1937-38. In 1938 she accepted a position as an Agricultural Scientist, Horticulture Division, at the Central Experimental Farm in Ottawa, Ontario, Canada. Her early specialty was plant histology and cytology.T.H. Anstey, Agriculture Canada. One Hundred Harvests, Research Branch, Agriculture Canada, 1886-1986.
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When infections such as these occur elsewhere in the body, the host defense system, able to travel the body via the circulatory system, is, more often than not, capable of appropriately gaining access to the site of infection in order to mount a proper and successful retaliation.Ross, MH, Histology: A Text and Atlas, 3rd Edition. Philadelphia: Lippincott, Williams and Wilkins, 1995. page 315.
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According to the Journal of the History of the Neurosciences, Dr. Lewy became interested in studying more about the brain (neurology), because of the discovery that Alois Alzheimer made in 1906. The article mentions that the third reported case of Alzheimer's disease had histological structures that happened to be similar to Lewy body histology slides, but the contribution was not given to Lewy's finding.
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In 1901, she became the first woman faculty member of UTMB. She gave the opening speech on the first day of school at UTMB in 1912. In 1915, she became a full professor of embryology and ten years later in 1925, a full professor of histology. On May 27, 1927 she suffered from a sudden illness due to heart disease and died the same day.
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The skin fold is characterized by skin redundancy that is responsible partly, often in combination with connective tissue attachments, for the skin crease. It is essential to use appropriate terms that accurately reflect the anatomic structure and histology when referring to the skin lines.Mallouris, A., Yiacoumettis, A., Thomaidis, V., Karayiannakis, A., Simopoulos, C., Kakagia, D., & Tsaroucha, A. K. (2012). A record of skin creases and folds.
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Hogan MJ, Alvarado JA, Weddell E: Histology of the Human Eye. Philadelphia: WB Saunders, 1971 With ageing, this layer becomes thinner. The function of the Bowman's membrane remains unclear and appears to have no critical function in corneal physiology. Recently, it is postulated that the layer may act as a physical barrier to protect the subepithelial nerve plexus and thereby hastens epithelial innervation and sensory recovery.
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Joan Dougherty (born March 2, 1927) was a Canadian politician in the province of Quebec, who represented Jacques-Cartier in the National Assembly of Quebec from 1981 to 1987. Born in Montreal, Quebec, Dougherty received a Bachelor of Science degree in 1947 and a Masters in histology in 1950 from McGill University. She did post-graduate studies at the Massachusetts Institute of Technology in biophysics.
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Many of the pioneer surgeons in the country including Dr. Sadegh Ghazi and Dr. Anwar Shakki received their surgical training from Dr. Motamed. Dr. Motamed is the first Iranian surgeon who conducted a gastrectomy and lumbar sympatectomy in Iran. He held surgical procedures classes in Motamed hospital, prior to which no educational hospital existed in Iran. He taught subjects such as pathology, histology, and embryology.
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This can be done to slides processed by the chemical fixation or frozen section slides. To see the tissue under a microscope, the sections are stained with one or more pigments. The aim of staining is to reveal cellular components; counterstains are used to provide contrast. The most commonly used stain in histology is a combination of hematoxylin and eosin (often abbreviated H&E;).
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Admission to the medical schools is based on entrance examination that can be undergone once a year. The program is a 6-year program in general medicine with a strictly preclinical and clinical division. The preclinical years are the two first, and are purely theoretical. They consist of subjects such as cell biology, genetics, biophysics, medical chemistry, anatomy, biochemistry, histology, embryology and so on.
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He studied medicine in Havana and Barcelona, earning his medical licence in 1877. Afterwards, he relocated to Paris, where he studied histology with Louis-Antoine Ranvier (1835–1922). In Paris, he interned under several renowned physicians, including urologist Jean Casimir Félix Guyon (1831–1920), who served as an important influence to Albarrán's career. In 1892 he became professeur agrégé, followed by chirurgien des hôpitaux two years later.
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However, there is a clear distinction between the two. Scylacops was distinctly cyclical with intermediate growth, where periods of fast growth were interrupted by periods of slow growth or halting of growth. Aelurognathus sustained fast growth early in ontogeny only to be interrupted at a later stage of growth . Aelurognathus tigriceps SAM-PK-10188’s histology shows wide zones separated by annuli and LAGs.
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Augusto Murri (8 September 1841, Fermo, Marche - 11 November 1932) was an Italian physician. Appointed to the Chair of Clinical Medicine at Bologna in 1875 he was regarded as one of the most illustrious clinical doctors and innovators of his times (in Pathological Anatomy, Histology, Microbiology and Experimental Physiopathology). Became also the Rector of the Alma Mater Studiorum, and later a member of the Italian Parliament (1891).
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The location of tumors is closely related to their histology. The majority of glioneuronal tumors occur in the temporal lobe. Some data have shown that oligodendroglial tumors were more likely to be located in frontal lobe, whereas astrocytomas were more commonly found in temporal locations. It may be postulated that tumor-related seizures have unique characteristics, which may share some common genetic pathways with tumorigenesis.
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Subsequently, he studied for two years in Germany at Freiburg and Berlin. Returning to Saint Petersburg, he served as professor of histology and embryology from 1903 until 1922. While he could teach and pursue his research after the Russian Revolution he could not arrange himself with living in communist Russia. He fled 1922 with his sister, his wife and his adopted son to the USA.
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Golding-Bird Cuthbert Hilton Golding-Bird (1848–1939) was an English surgeon at Guy's Hospital, fellow of the Royal College of Surgeons, and lecturer to medical students. He was skilled in histology, invented a dilator for use in tracheotomies, and pioneered a new gastroenterological surgical procedure. Outside of medicine, Golding-Bird was known as a collector of clocks and publisher of books on local archaeology.
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His research concentrated on the epidemiology of skin diseases and histology, noting the importance of microscopic inspection of skin cells. During his career, he was the first to describe or name diseases such as granuloma annulare and erythema elevatum diutinum. In 1888, Crocker published Diseases of the Skin: their Description, Pathology, Diagnosis and Treatment, a textbook that helped to establish him as a leading figure in dermatology.
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There is still not a consensus among biologists that the American and Chinese alligators belong to the same genus, despite multiple studies comparing the biochemistry, histology, and various other aspects of the two crocodilians. The genus, Alligator, is based on the Spanish word el lagarto, which translates to "the lizard". The specific name, sinensis, is from the Latin plural possessive sinaensis, meaning "belonging to China".
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The histology of the ileocecal valve shows an abrupt change from a villous mucosa pattern of the ileum to a more colonic mucosa. A thickening of the muscularis mucosa, which is the smooth muscle tissue found beneath the mucosal layer of the digestive tract. A thickening of the muscularis externa is also noted. There is also a variable amount of lymphatic tissue found at the valve.
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In October 1942 he was deported to the Theresienstadt concentration camp, where he died on August 26, 1944. Hirschfeld was the author of many publications in the fields of hematology and histology. He is known for his studies of blood diseases and his research on the pathology of the spleen. With hematologist Artur Pappenheim (1870-1916) he conducted studies involving microscopic differentiation of blood cells.
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The Italian Journal of Anatomy and Embryology (sometimes abbreviated as the IJAE) is a quarterly peer-reviewed academic journal of anatomy and embryology. It was established in 1901 by Giulio Chiarugi and is published by Firenze University Press. It is the official journal of the Italian Society of Anatomy and Histology. The journal publishes original papers, invited review articles, historical article, commentaries, obituitary, and book reviews.
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CCL8 is a potent inhibitor of HIV1 by virtue of its high- affinity binding to the receptor CCR5, one of the major co-receptors for HIV1.; In addition, CCL8 attributes to the growth of metastasis in breast cancer cells. The manipulation of this chemokine activity influences the histology of tumors promoting steps of metastatic processes. CCL8 is also involved in attracting macrophages to the decidua in labor.
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Methyl blue is a chemical compound with the molecular formula C37H27N3Na2O9S3. It is used as a stain in histology, and stains collagen blue in tissue sections. It can be used in some differential staining techniques such as Mallory's connective tissue stain and Gömöri trichrome stain, and can be used to mediate electron transfer in microbial fuel cells. Fungal cell walls are also stained by methyl blue.
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The term fibromatosis refers to a group of soft tissue tumors which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well- differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence. It is classed by the World Health Organization as an intermediate soft tissue tumor related to the sarcoma family.
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Philippe Gaucher Philippe Charles Ernest Gaucher () (July 26, 1854 – January 25, 1918) was a French dermatologist born in the department of Nièvre. He received his medical doctorate in 1882, and soon after headed a medical clinic at Necker Hospital. During the subsequent years he was an instructor at several hospital clinics in Paris. He taught classes on pathological anatomy, bacteriology and histology, as well as dermatology.
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PIPES has two pKa values. One pKa (6.76 at 25°C) is near the physiological pH which makes it useful in cell culture work. Its effective buffering range is 6.1-7.5 at 25° C. The second pKa value is at 2.67 with a buffer range of from 1.5 - 3.5. PIPES has been documented minimizing lipid loss when buffering glutaraldehyde histology in plant and animal tissues.
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Through his efforts, dental experts escaping persecution by the Nazis in Europe came to the faculty of the University of Illinois at Chicago College of Dentistry, creating the college's international reputation. Schour served as president of the International Association for Dental Research and head of the University of Illinois at Chicago College of Dentistry Department of Histology. He was dean of the college from 1956 to 1964.
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Two years later the University made him the first Bosch Professor of Embryology and Histology and he remained in that role until retiral in 1956. His position as Bosch Professor was filled by Kenneth Wollaston Cleland. In 1930 he was elected a Fellow of the Royal Society of Edinburgh. His proposers were Arthur Robinson, Sir Edward Albert Sharpey-Schafer, James Lorrain Smith and Charles George Lambie.
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The most frequently used extractants for this purpose are dibutyl glycol, methyl isobutyl ketone, tributyl phosphate, dichlorodiethyl ether (chlorex). In histology, chlorauric acid is known as "brown gold chloride", and its sodium salt NaAuCl4 as "gold chloride", "sodium gold chloride" or "yellow gold chloride". The sodium salt is used in a process called "toning" to improve the optical definition of tissue sections stained with silver.
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The newly formed tissue were histologically examined. Resolution of symptoms of inflammation related to enlargement of foramen and overinstrumentation were observed in as early as 17 days. Resolution of apical periodontitis and signs and symptoms of inflammation and radiographic evidence of continued root development and apical narrowing were demonstrated in all teeth. Histology wise, ingrowth of connective tissue into the canal space was observed.
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The mammographic density is correlated with the collagen density, thus SHG can be used for identifying breast cancer. SHG is usually coupled to other nonlinear techniques such as Coherent anti-Stokes Raman Scattering or Two-photon excitation microscopy, as part of a routine called multiphoton microscopy (or tomography) that provides a non-invasive and rapid in vivo histology of biopsies that may be cancerous.
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There are three main histological subtypes found at post-mortem: FTLD-tau, FTLD-TDP, and FTLD-FUS. Dementia lacking distinctive histology (DLDH) is a rare and controversial entity. New analysis has allowed many cases previously described as DLDH to be reclassified into one of the positively defined subgroups. In rare cases, patients with clinical FTD were found to have changes consistent with Alzheimer's disease on autopsy.
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In biology, tissue is a cellular organizational level between cells and complete organs. A tissue is an ensemble of similar cells and their extracellular matrix from the same origin that together carry out a specific function. Organs are then formed by the functional grouping together of multiple tissues. The study of human and animal tissues is known as histology or, in connection with disease, histopathology.
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The relevance of B symptoms in non-Hodgkin lymphoma is less clear, although B symptoms tend to correlate with disease that is either more widespread or of a higher histologic grade.Malignant lymphoma: the histology and staging of 473 patients at the National Cancer Institute. Anderson T; Chabner BA; Young RC; Berard CW; Garvin AJ; Simon RM; DeVita VT Jr. Cancer 1982 Dec 15;50(12):2699–707.
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The aggregate of cells which eventually form a tooth are derived from the ectoderm of the first branchial arch and the ectomesenchyme of the neural crest.Cate, A. R. Ten, Oral Histology: Development, Structure, and Function, 5th ed. (Saint Louis: Mosby-Year Book, 1998), p. 102. . As in all cases of tooth development, the first hard tissue to begin forming is dentin, with enamel appearing immediately afterwards.
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There, he was habilitated and made a full professor in 1913. From 1910 to 1916, he served as physician and chairman of the Anatomical Laboratory at the University Psychiatric Clinic. Brodmann moved to Halle in 1916 to work in the Nietleben Municipal Hospital. Finally, in 1918, he accepted an invitation from the University of Munich to direct the group of histology at Psychiatric Research Center.
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An improved understanding of mesenteric structure and histology has enabled a formal characterization of mesenteric lymphangiology. Stereologic assessments of the lymphatic vessels demonstrate a rich lymphatic network embedded within the mesenteric connective tissue lattice. On average, vessels occur every , and within from the mesocolic surfaces—anterior and posterior. Lymphatic channels have also been identified in Toldt's fascia, though the significance of this is unknown.
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In 1869 he was habilitated for physiology at Vienna, and during the next year became Karl Ewald Konstantin Hering's assistant in Prague. In 1872 he became an associate professor and in 1887 a full professor. From 1880 he was director at the newly founded institute of histology. Mayer made several important contributions particularly concerning the physiology of the heart and vessels, respiration and intestines.
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Histology of the affected area commonly shows dense perivascular lymphocytic infiltration with reticulated degeneration of the epidermis. A study by Iwatsuki et al. detected Epstein-Barr virus (EBV) positive T-cells in the perivascular infiltration on biopsy in 28/29 patients tested. Antibody titers to EBV were measured in 14 of these patients and only five had abnormal antibody patterns consistent with chronic active EBV infection.
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Low magnification view of the histology of chronic hypersensitivity pneumonitis. The interstitium is expanded by a chronic inflammatory infiltrate. Two multinucleated giant cells can be seen within the interstitium at left, and a plug of organizing pneumonia at bottom left. Lung biopsies can be diagnostic in cases of chronic hypersensitivity pneumonitis, or may help to suggest the diagnosis and trigger or intensify the search for an allergen.
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Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV/AIDS. It improves the seroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long-term use of lamivudine leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.
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Helicobacter pylori colonized on the surface of regenerative epithelium, stained with the Warthin-Starry method. Clusters of bacteria (arrow) shown on Warthin–Starry stain. The Warthin–Starry stain (WS) is a silver nitrate-based staining method (a silver stain) used in histology. It was first introduced in 1920 by American pathologists Aldred Scott Warthin (1866-1931) and Allen Chronister Starry (1890-1973), for the detection of spirochetes.
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Eosin Y also called C.I. 45380 or C.I. Acid Red 87, is the form of eosin most commonly used in histology, most notably in the H&E; (Haematoxylin and Eosin) stain. Eosin Y is also widely used in the Papanicolaou stain (or Pap stain used in the Pap test) and the Romanowsky type cytologic stains. It is also used as a photosensitizer in organic synthesis.
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Angelo Ruffini (Pretare of Arquata del Tronto; 1864–1929) was an Italian histologist and embryologist. He studied medicine at the University of Bologna, where beginning in 1894 he taught classes in histology. In 1903 he attained the chair of embryology at the University of Siena. He was the first to describe small encapsulated nerve endings (mechanoreceptors) which were to become known as Ruffini corpuscles.
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A dissected body, lying prone on a table - one of the series of anatomical paintings made by the 19th Century English painter . The history of anatomy in the 19th century saw anatomists largely finalise and systematise the descriptive human anatomy of the previous century. The discipline also progressed to establish growing sources of knowledge in histology and developmental biology, not only of humans but also of animals.
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The bone histology of Thrinaxodon indicates that it most likely had very rapid bone growth during juvenile development, and much slower development throughout adulthood, giving rise to the idea that Thrinaxodon reached peak size very early in its life.Botha J. Chinsamy A. 2005. Growth patterns of Thrinaxodon liorhinus, a non-mammalian cynodont from the lower Triassic of South Africa. Paleontology. 48(2): 385-394.
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A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast. In histology, it is very difficult to distinguish it from the other "-blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast). The cytoplasm is blue in an H&E; stain, indicating that it is basophilic. Proerythroblasts arise from the CFU-e (colony-forming unit erythroid) cells, and give rise to basophilic erythroblasts.
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They are differentiated with examination of the tumors' histology. Hereditary recurrent pneumothorax or pulmonary cysts are associated with Marfan syndrome, Ehlers–Danlos syndrome, tuberous sclerosis complex (TSC), alpha1-antitrypsin deficiency, and cystic fibrosis. Non-hereditary recurrent pneumothorax and/or pulmonary cysts can occur with Langerhans cell histiocytosis and lymphangioleiomyomatosis. These conditions are differentiated from Birt–Hogg–Dubé through examining the patient history and performing a physical examination.
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Acridine yellow, also known as acridine yellow G, acridine yellow H107, basic yellow K, and 3,6-diamino-2,7-dimethylacridine, is a yellow dye with strong bluish-green fluorescence. It is a derivate of acridine. In histology, it is used as a fluorescent stain, and as a fluorescent probe for non-invasive measurements of cytoplasmic pH changes in whole cells. It is also used as a topical antiseptic.
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The differentiation between primitive neuroectodermal tumor in the central nervous system and medulloblastoma is recent. According to the World Health Organization, both tumors have the same histology but primitive neuroectodermal tumors occur outside the cerebellum. Moreover, it has been documented that both have different genetic expression and mutations. Another essential difference between them is the location of their respective blood vessels within the brain.
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There are six comprehensive teaching laboratories at university level -- Morphology, Function, Chemicoanalysis, Clinical Skills, Computer and Human Anatomy -- and 16 specialty laboratories like Gene and Histology Engineering, Dentistry, and Nursing which are equipped with advanced Imaging PACS System, Digital Network Interactive Laboratory Teaching System, BL-410 Biological Function Experiment System, and so on. The Experimental Center of Basic Medicine is an experimental and teaching demonstration center for universities in Shandong Province. Anatomy, Medical Ethics, Pathology, Physiology, Histology and Embryology, Pharmacology and Medical Imaging are assessed as the excellent subjects at provincial level. WFMU has undertaken 90 teaching and research projects at provincial level or above and has been awarded 24 prizes in teaching, experiment and research since 2004. WFMU has one discipline which offers post for “Taishan Scholars”, seven key provincial academic disciplines and laboratories, including Anatomy and Histological Embryology, Surgery, Medical Radiology, Ophthalmology, Immunology, Applied Pharmacology, Dental medicine.
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Some Nobel laureates have paved the way with clear statements of good practice: In the preface to his Histology Histology of the Nervous System: Spanish edition Santiago Ramón y Cajal wrote that "Practitioners will only be able to claim that a valid explanation of a histological observation has been provided if three questions can be answered satisfactorily: what is the functional role of the arrangement in the animal; what mechanisms underlie this function; and what sequence of chemical and mechanical events during evolution and development gave rise to these mechanisms?" Allvar Gullstrand described the problems that arise when approaching the optics of the eye as if they were as predictable as camera optics. Charles Scott Sherrington, considered the brain to be the "crowning achievement of the reflex system", (which can be interpreted as opening all aspects of perception to simple formulae expressed over complex distributions).
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CCPDMA is subject to the basic principles of histology sectioning. From a physical standpoint, the true margin is never assessed because a thin face margin has to be cut through in order to make the slide for examination. Therefore, a true and complete assessment of all margins is never achieved. Serial sectioning allows CCPDMA approaches near-complete evaluation of the surgical margin and may be performed by pathologists, dermatologists, and surgeons.
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After several years of teaching at Rochester, Allen was appointed professor and chairman of the Department of Obstetrics and Gynecology at Washington University's School of Medicine in St. Louis. He contributed original papers on the histology and physiology of the female reproductive organs, bringing him many national and international awards. He was the first graduate of the Medical School in Rochester to be elected to that university's board of trustees.
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The cells of the periodontal ligaments include osteoblasts, osteoclasts, fibroblasts, macrophages, cementoblasts, and epithelial cell rests of Malassez. Consisting of mostly Type I and III collagen, the fibers are grouped in bundles and named according to their location. The groups of fibers are named alveolar crest, horizontal, oblique, periapical, and interradicular fibers.Listgarten, Max A. "Histology of the Periodontium: Principal fibers of the periodontal ligament," University of Pennsylvania and Temple University.
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The first half of the medical curriculum is dedicated mostly to teaching the fundamentals of, or basic subjects relevant to, medicine, such as anatomy, histology, physiology, pharmacology, genetics, microbiology, ethics, and epidemiology. This instruction can be organized by discipline or by organ system. Teaching methods can include traditional lectures, problem-based learning, laboratory sessions, simulated patient sessions, and limited clinical experiences. The remainder of medical school is spent in clerkship.
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He studied medicine in Paris, and later served as prosector in Strassburg. In 1873 he became agrégé, subsequently becoming director of the anthropological laboratory at the École des Hautes Etudes and an anatomy professor at the École Supérieur des Beaux-Arts. In 1885 he replaced Charles-Philippe Robin (1821–1895) as professor of histology at the medical faculty in Paris. In 1892 he became a member of the Académie de Médecine.
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Rhabdomyoma is a benign mesenchymal tumor of skeletal muscle, separated into two major categories based on site: Cardiac and extracardiac. They are further separated by histology: fetal (myxoid and cellular), juvenile (intermediate), and adult types. Genital types are recognized, but are often part of either the fetal or juvenile types. The fetal type is thought to recapitulate immature skeletal muscle at about week six to ten of gestational development.
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In terms of sampling technique, a biopsy generally refers to a preparation where the normal tissue structure is preserved, availing for examination of both individual cells and their organization for the study of histology, while a sample for cytopathology is prepared primarily for the examination of individual cells, not necessarily preserving the tissue structure. Examples of biopsy procedures are bone marrow biopsy, brain biopsy, skin biopsy and liver biopsy.
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Andrewes succeeded him in these posts and continued in office for thirty years. In 1912 Andrewes's lectureship in pathology was raised by the University of London to a professorship. He did research on the classification of streptococci, the histology of lymphadenoma, immunology, and arterial degeneration. Horder, as well as John Hannah Drysdale, Hugh Thursfield, Frank Atcherley Rose, and W. Girling Ball, were, early in their careers, demonstrators in pathology under Andrewes.
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In 1929 he was appointed assistant in Anatomy "secretary second class" and an unpaid assistant in the Laboratory of Histology-Embryology, while working to maintaine himself. In 1934 he received his degree with a grade of "Excellent" and in 1939 submitted his doctoral thesis entitled "Contribution to the study of human renal artery (after own observations)", so was acclaimed Doctor of Medicine from the University of Athens, with "Excellent".
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Savvas offered a premium educational project to prospective physicians on the Science of Anatomy, Histology and Embryology human both theoretical and laboratory level. He has published and research work. During the tenure of Professor Al. Savva occurred transportation Anatomy of the historic building of the road Katsimidou to the new buildings of the Medical School campus thus fulfilling the dream of Professor for a modern and well-equipped Anatomy.
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Xylene is used in the laboratory to make baths with dry ice to cool reaction vessels, and as a solvent to remove synthetic immersion oil from the microscope objective in light microscopy. In histology, xylene is the most widely used clearing agent. Xylene is used to remove paraffin from dried microscope slides prior to staining. After staining, microscope slides are put in xylene prior to mounting with a coverslip.
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The Chronobiology Laboratory studies the biological rhythms of insects. It was established in 1987, when researcher-in-charge Mirian David Marques finished her internship in chronobiology at the University of Minnesota. Research methods used in the laboratory include automated (or visual) records of insect behavior. When rhythms are detected the neuroanatomy and neurophysiology of specimens are studied, searching for rhythm-generating centers using histology, histochemistry and molecular biology.
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He was also a member of the Ecology and Toxicology Centre and the European Chemical Industry Council (CEFIC) in Brussels. In recent years he co-operated with the Institute of Social, Occupational and Environmental Medicine at the Gutenberg University, as well as with the Department of Histology and Embryology of the Medical University of Łódź in order to continue and to publish his works on carcinogenic aromatic amines.
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He attempted to reorganize the university medical school after the fire, insisting on the erection of a building near Bellevue Hospital Center. His plans, all adopted later, being rejected, Dr. Van Buren resigned. In 1868 he became professor of surgery in the Bellevue Hospital Medical College, a position which he retained until his death. In 1854 he translated from the French Charles Morel's Histology, and afterwards, Bernard and Huette's Operative Surgery.
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Perhaps due to the mechanism whereby the skin's immune system encapsulates pigment particles in fibrous tissue, tattoo inks have been described as "remarkably nonreactive histologically".Tattoo lasers / Histology, Suzanne Kilmer, eMedicine However, some allergic reactions have been medically documented. No estimate of the overall incidence of allergic reactions to tattoo pigments exists. Allergies to latex are apparently more common than to inks; many artists will use non- latex gloves when requested.
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Similar to the frozen section procedure employed in medicine, cryosectioning is a method to rapidly freeze, cut, and mount sections of tissue for histology. The tissue is usually sectioned on a cryostat or freezing microtome. The frozen sections are mounted on a glass slide and may be stained to enhance the contrast between different tissues. Unfixed frozen sections can be used for studies requiring enzyme localization in tissues and cells.
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Artifacts are structures or features in tissue that interfere with normal histological examination. Artifacts interfere with histology by changing the tissues appearance and hiding structures. Tissue processing artifacts can include pigments formed by fixatives, shrinkage, washing out of cellular components, color changes in different tissues types and alterations of the structures in the tissue. An example is mercury pigment left behind after using Zenker's fixative to fix a section.
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Alexander Alexandrowitsch Maximow (; – December 4, 1928) was a Russian- American scientist in the fields of Histology and Embryology whose team developed the hypothesis about the existence of "polyblasts". Maximow is renowned for his experimental work on the unitarian theory of hematopoiesis: all blood cells develop from a common precursor cell.Biography of Alexander A. Maximow The University of Chicago Library Maximow served as a Corresponding Member of the Russian Academy of Sciences.
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The term "germinoma" most often refers to a tumor in the brain that has a histology identical to two other tumors, dysgerminoma in the ovary and seminoma in the testis. Since 1994, MeSH has defined germinoma as "a malignant neoplasm of the germinal tissue of the gonads, mediastinum, or pineal region" and within its scope included both dysgerminoma and seminoma. Collectively, these are the seminomatous or germinomatous tumors.
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Multiple minute digitate hyperkeratosis (also known as "Digitate keratoses," "Disseminated spiked hyperkeratosis," "Familial disseminated piliform hyperkeratosis," and "Minute aggregate keratosis") is a rare cutaneous condition, with about half of cases being familial, inherited in an autosomal dominant fashion, while the other half are sporadic. This disease has a unique histology, so a biopsy and further tests should be done to confirm the diagnosis and rule out other disorders and malignancy.
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The sheath is also responsible for multiple or accessory roots (medial growth) and lateral or accessory canals in the root (break in epithelium).Ten Cate's Oral Histology, Nanci, Elsevier, 2013, p. 174 It is controversial, but HERS may be involved in cementogenesis and the secreting of cementum, or that HERS-derived products might be related to enamel-related molecules, and that these proteins might initiate acellular cementum formation.
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During his time there he was a member of the Munich Corps Hubertia fraternity. He continued his studies in Jena under the tutelage of Matthias Jacob Schleiden. Under him, he learned more extensively about botany and pioneered his work in microscopy and his research on the structure of plant's bodies. From July 1869, he worked at the Technische Universität Darmstadt, as a Professor of Botany and Zoology, Botany, and Cellular Histology.
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In the Indian variant, nodules enlarge with time and form plaques but rarely ulcerate, but nodules from the African variety often ulcerate as they progress. Nerve involvement is common in African variety but rare in Indian subcontinent. Histology demonstrates a mixture of chronic inflammatory cells; there can be macrophage or epitheloid granuloma. Parasite concentration is not consistent among studies, perhaps reflecting low sensitivity of diagnostic methods used in earlier entries.
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The structure of dentin is an arrangement of microscopic channels, called dentinal tubules, which radiate outward from the pulp chamber to the exterior cementum or enamel border.Ross, Michael H., Kaye, Gordon I. and Pawlina, Wojciech (2003) Histology: a text and atlas. 4th edition, p. 450. . The diameter of the dentinal tubules is largest near the pulp (about 2.5 μm) and smallest (about 900 nm) at the junction of dentin and enamel.
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Theodor Schiebler has researched tissues of the neuroendocrine system, the kidney and the placenta using methods of histochemistry and electron microscopy and is the author of over 150 scientific publications. In addition, Schiebler was the author of an anatomical textbook, which was published in ten editions (most recently in 2007). He also translated and supplemented the histology textbook by Luiz Carlos Uchôa Junqueira (last edition with Schiebler's collaboration in 1996).
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The sandstones are interspersed by reddish-brown siltstones and mudstones which were deposited as silt sediments washed down the braided channels further down the Karoo BasinSmith, R., Rubidge, B., & Van der Walt, M. (2012). Therapsid biodiversity patterns and paleoenvironments of the Karoo Basin, South Africa. Forerunners of Mammals: Radiation, Histology, Biology. Indiana University Press, Indianapolis, Indiana, 30-62.. The mudstones here often contain cracks which are infilled with sandstone.
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The typically benign odontogenic tumor known as ameloblastoma was first recognized in 1827 by Cusack but did not yet have any designation. In 1885, this kind of odontogenic neoplasm was designated as an adamantinoma by Malassez and was finally renamed to the modern name ameloblastoma in 1930 by Ivey and Churchill. Some authors still confusingly misuse the term adamantinoma to describe ameloblastomas, although they differ in histology and frequency of malignancy.
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The first two were correct: # The cell is the unit of structure, physiology, and organization in living things. # The cell retains a dual existence as a distinct entity and a building block in the construction of organisms. By the 1860s, these tenets were the accepted basis of cell theory, used to describe the elementary anatomical composition of plants and animals. Schwann's theory and observations created a foundation for modern histology.
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After graduating from medical school, Bishop moved to Berkeley to teach histology in the anatomy department at the University of California Medical School until 1923. During this time, Bishop did her medical research with anatomist and endocrinologist Herbert McLean Evans. Together, they published a monograph on the vital staining of connective tissue cells. The discovery of Vitamin E came as a result of the study of the reproductive cycle of rats.
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Alizarin Red S, as sold for use as a histologic stain. Alizarin Red S is used in histology and histopathology to stain, or locate calcium deposits in tissues. In the presence of calcium, Alizarin Red S, binds to the calcium to form a Lake pigment that is orange to red in color. Whole specimens can be stained with Alizarin Red S to show the distribution of bone, especially in developing embryos.
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Carcinosarcoma of the uterus In gross appearance, MMMTs are fleshier than adenocarcinomas, may be bulky and polypoid, and sometimes protrude through the cervical os. On histology, the tumors consist of adenocarcinoma (endometrioid, serous or clear cell) mixed with the malignant mesenchymal (sarcoma) elements; alternatively, the tumor may contain two distinct and separate epithelial and mesenchymal components. Sarcomatous components may also mimic extrauterine tissues (e.g., striated muscle, cartilage, adipose tissue, and bone).
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Bengt Olof Torsten Falck (born 16 January 1927 in Malmö) is a Swedish scientist, who is professor emeritus at the Faculty of Medicine at Lund University, Sweden. Falck has published numerous works in the fields of histology, endocrinology and neurobiology. Bengt Falck is the son of Hans Falck, city court judge in Malmö, Sweden, and Maria Hagander. He married Eva Torp in 1951, and together they had four children.
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Acta physiol.scand. Suppl. 163, 1959, 47: 1-101 Between 1960 and 1970 he acted as associate professor, before becoming a full professor of histology in 1970, all at the University of Lund, Sweden. In 1960–61 Falck and Nils-Åke Hillarp developed the Falck-Hillarp fluorescence method. This technique made it possible to study biologically active substances called monoamines – dopamine, noradrenaline, adrenaline and serotonin – on the cellular level employing fluorescence microscope.
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It is used as a general stain in histology, as a counterstain in combination with other dyes, and for many staining methods. Together with Janus Green B, it is used to stain embryonal tissues and supravital staining of blood. Can be used for staining Golgi apparatus in cells and Nissl granules in neurons. In microbiology, it is used in the MacConkey agar to differentiate bacteria for lactose fermentation.
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He was a full member of Department of medical sciences at Serbian Academy of Sciences and Arts. Bumbasirevic was a member of Academia Medica di Roma since 1990. He is famous for his methods in orthopaedic surgery. His son is Vladimir Bumbasirevic, full professor of histology at the School of medicine at the University of Belgrade and also a full member of Serbian Academy of Sciences and Arts.
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In 2010, the Rush Medical College curriculum underwent an extensive transformation as it implemented a system-based curriculum. Each organ system is organized into an individual block that integrates material from anatomy, biochemistry, histology, physiology, microbiology, pathophysiology, immunology, and pharmacology. Preclinical years are graded as Pass/Fail, and clinical years are graded as Honors, High Pass, Pass, Fail. Concurrently, students in the first two years are enrolled in the EXPLORE Program.
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The topical application of monobenzone in animals increases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation. The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes.
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Hans von Hebra (1847–1902) wrote the classical description of the disease in a paper published in the January 1870 issue of the Wiener Medizinische Wochenschrift.Hebra.Garrison & Morton (GM 3277). Hans von Hebra was the son of Czech born dermatologist Ferdinand Ritter von Hebra (1816–1880), founder of the New Vienna School of Dermatology. He was assisted by M. Kohn who provided much of the histology for the paper.
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Disse studied at the University of Erlangen, and after graduation became an assistant to anatomist Heinrich von Waldeyer-Hartz (1836-1921) at Strassburg. From 1880 to 1888 he was an instructor at the University of Tokyo, and afterwards became an associate professor at the University of Göttingen. From 1895 to 1912 he was a professor at the University of Marburg. He specialized in the fields of microscopic anatomy, embryology and histology.
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In the EU, bevacizumab, in addition to platinum-based chemotherapy, is indicated for first-line treatment of adults with unresectable advanced, metastatic or recurrent non-small cell lung cancer other than predominantly squamous cell histology. Bevacizumab, in combination with erlotinib, is indicated for first-line treatment of adults with unresectable advanced, metastatic or recurrent non-squamous non-small cell lung cancer with Epidermal Growth Factor Receptor (EGFR) activating mutations.
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Histology tests from a skin biopsy can identify muriform cells that are commonly found in chromoblastomycosis. Identifying the specific agent that caused chromoblastomycosis can be done by PCR assays or culturing the fungus by growing it on an agar plate and observing the colony morphology and sporulation characteristics. However, C. carrionii grows quite slowly in culture, so significant results cannot be obtained until after 4–6 weeks of incubation.
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The alveolar process (Entry "alveolar" in Merriam-Webster Online Dictionary) (also called the alveolar bone) is the thickened ridge of bone that contains the tooth sockets (dental alveoli) on the jaw bones that hold teeth. In humans, the tooth-bearing bones are the maxilla and the mandible.Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 219 The curved part of each alveolar process on the jaw is called the alveolar arch.
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Using a similar mechanism, freshwater teleost fish use these cells to take in salt from their dilute environment to prevent hyponatremia from water diffusing into the fish. In the context of freshwater fish, ionocytes are often referred to as "mitochondria-rich cells", to emphasis their high density of mitochondria.Fernandes, M.N. (2019) "Respiration and Ionic-Osmoregulation". In: Formicki K and Kirschbaum F (Eds.) The Histology of Fishes pages 246–266, CRC Press. .
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Christian Georg Schmorl at Who Named It. For most of his career (1894-1931) he was associated with the city hospital in Dresden (Krankenhaus Dresden-Friedrichstadt). Schmorl is remembered for his work in histology and his studies of the human skeleton. He created an histological stain especially designed to show the canaliculi and lamellae in sections of bone. He also described protrusions of the intervertebral disc into the vertebral body.
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Glyoxal is a valuable building block in organic synthesis, especially in the synthesis of heterocycles such as imidazoles. A convenient form of the reagent for use in the laboratory is its bis(hemiacetal) with ethylene glycol, 1,4-dioxane-2,3-diol. This compound is commercially available. Glyoxal solutions can also be used as a fixative for histology, that is, a method of preserving cells for examining them under a microscope.
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In histology, osteoid is the unmineralized, organic portion of the bone matrix that forms prior to the maturation of bone tissue. Osteoblasts begin the process of forming bone tissue by secreting the osteoid as several specific proteins. When the osteoid becomes mineralized, it and the adjacent bone cells have developed into new bone tissue. Osteoid makes up about fifty percent of bone volume and forty percent of bone weight.
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Robert Heinrich Johannes Sobotta (31 January 1869, in Berlin - 20 April 1945, in Bonn) was a German anatomist. He studied medicine in Berlin, where he subsequently worked as a second assistant at the institute of anatomy. From 1895 he served as prosector at the institute for comparative anatomy, embryology and histology at Würzburg. In 1903 he became an associate professor and in 1912 a full professor of topographical anatomy.
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Imaging tests include: X-rays, CT scans, MRI, and ultrasound. Histology is another important diagnostic tool to use. In the past, the PAS staining technique has proven beneficial in helping determine if infections are caused by Echinococcus multiocularis. More recently, a new immunohistochemistry technique that uses a monoclonal antibody (Em2G11) has provided professionals with more accuracy and precision in diagnosing Echinococcus multiocularis and distinguishing it from other species like Echinococcus granulosus.
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Water blue, also known as aniline blue, Acid blue 22, Soluble Blue 3M, Marine Blue V, or C.I. 42755, is a chemical compound used as a stain in histology. Water blue stains collagen blue in tissue sections. It is soluble in water and slightly soluble in ethanol. Water blue is also available in mixture with methyl blue, under the names Aniline Blue WS, Aniline blue, China blue, or Soluble blue.
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In histology, a clear cell is a cell that shows a clear cytoplasm when stained with hematoxylin and eosin (H&E;). Normally, clear cells are secretory cells in the epithelium, and are one of the components of eccrine sweat glands. A clear cell's plasma membrane is highly folded, more so on the apical and lateral surfaces. The cytoplasm of clear cells contains large amounts of glycogen and many mitochondria.
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The authors estimated 45 to 65 total days of adult nest attendance for laying, brooding, and hatching. Varricchio et al. (2008) examined the bone histology of Two Medicine troodont specimen MOR 748 and found that it lacked the bone resorption patterns that would indicate it was an egg-laying female. They also measured the ratio of the total volume of eggs in clutches to the body mass of the adult.
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Wundt illusion During the Heidelberg years from 1853 to 1873, Wundt published numerous essays on physiology, particularly on experimental neurophysiology, a textbook on human physiology (1865, 4th ed. 1878) and a manual of medical physics (1867). He wrote about 70 reviews of current publications in the fields of neurophysiology and neurology, physiology, anatomy and histology. A second area of work was sensory physiology, including spatial perception, visual perception and optical illusions.
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Scratching sheep over the rump area may lead to a nibbling reflex, which is characteristic for the condition. Signs of a chronic systemic disease appear later, with weight loss, anorexia, lethargy, and death. Post mortem examination is important for the diagnosis of scrapie. Histology of tissues shows accumulation of prions in the central nervous system, and immunohistochemical staining and ELISA can also be used to demonstrate the protein.
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In 1930 Pastori became a lecturer of histology and professor of biology at the Università Cattolica del Sacro Cuore. This role required permission from the Vatican, however initially it was refused. After Pastori referred to the precedent of Maria Gaetana Agnesi,Agnesi was granted the chair of the mathematics and natural philosophy department of the University of Bologna in 1750. the Vatican gave permission for Pastori to take on the roles.
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In 1956 she moved from Zagreb to Ljubljana, where she worked at the oncological hospital. After four years she moved with her husband, Tvrtko Švob, to Sarajevo, where she worked at the Faculty of Medicine as an assistant in the field of histology and embryology. In 1964 she finished her doctoral thesis. From 1964 until 1979 Švob worked at the Institute for Skin and Venereal Diseases where she establish histopathological laboratory.
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In 1898 he succeeded his father as head of the second gynecological department at the Allgemeine Krankenhaus in Munich. In 1905 he became an associate professor at the university.Josef Albert Amann at Who Named ItAmann, Joseph Albert at Neue Deutsche Biographie He held a particular interest in the anatomy and histology of female genitalia. In 1897 he published Kurzgefasstes Lehrbuch der mikroskopisch-gynäkologischen Diagnostik, an influential textbook of microscopic gynecological diagnostics.
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Reconstruction of X. decheni Xenacanthus had a number of features that distinguished it from modern sharks. This freshwater shark was usually about one meter (3.3 feet) in length, and never longer than .Beck, Kimberley G.; oler-Gijón, Rodrigo; Carlucci, Jesse R.; Willis, Ray E. (December 2014). "Morphology and Histology of Dorsal Spines of the Xenacanthid Shark Orthacanthus platypternus from the Lower Permian of Texas, USA: Palaeobiological and Palaeoenvironmental Implications".
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Areola, more generally, is a small circular area on the body with a different histology from the surrounding tissue, or other small circular areas such as an inflamed region of skin. The mature human female nipple has several small openings arranged radially around the tip of the nipple (lactiferous ducts) from which milk is released during lactation. Other small openings in the areola are sebaceous glands, known as Montgomery's glands.
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He was born on 23 December 1938 in Brussels, Belgium. He obtained his first university degree in natural sciences from the University of Paris in 1960, and his doctorate in 1963. His thesis was supervised by Marcel Prenant, and focused on histology. He also did a larger "Doctorat d'état" (a degree that no longer exists but that was required at the time to supervise doctoral students or for academic advancement).
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Catsper2 is localized in the sperm tail and is responsible for regulation of hyperactivation. Catsper3 and Catsper4 are found in both, the testes and sperm and play an important role in the motility of hyperactivated sperm. Although Catsper seems to play an important role in sperm function, Catspers1-4 null mice have been found to have normal testicular histology, sperm counts and morphology, which is indicative of normal progression of spermatogenesis.
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Anomocephalus Otsheria Aulacocephalodon Kannemeyeria Anomodontia is an extinct group of non-mammalian therapsids containing many species from the Permian and Triassic periods, most of which were toothless, possibly endothermicBakker 1975 herbivores.Chinsamy-Turan, A. (2011) Forerunners of Mammals: Radiation - Histology - Biology, p.39. Indiana University Press, . Retrieved May 2012 Anomodonts were very diverse during the Middle Permian, including primitive forms like Anomocephalus and Patranomodon and groups like Venyukovioidea, Dromasauria, and Dicynodontia.
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The diagnosis of PTFL depends on a constellation of findings related to its presentation, tissue distribution, histology, and expression of certain proteins and genomic abnormalities. The disease occurs in males (~90% of cases) that are more often children, adolescents, or young adults who have enlargement of lymph nodes located in one or two nearby sites of the head or neck or less commonly, armpit or groin regions. Histopathological examination of the involved lymph nodes reveals medium- to large-sized lymphoblasts mixed with occasional macrophages and rare centrocytes and centroblasts that together form follicular structures that partially or completely replace the nodes' normal structure with irregularly shaped and merged follicles, abnormally attenuated mantle zones, and the presence of helper T-cells that are pushed to the periphery of the follicles. Its histology is most often rated as high grade and by this criterion defines the disease as an aggressive grade III lymphoma (see follicular lymphoma grading).
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He joined Emmanuel College in 1911 at the University of Cambridge where a contemporary was Birbal Sahni. He worked with Professor J. Stanley Gardiner on the comparative anatomy of Astraeid corals. He received the BA of Cambridge in 1913 and received a Balfour Fund grant to continue research. In 1914 he published on the histology of the Astraeid corals and received a Mackinnon Research studentship that allowed him to visit museums around the world.
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When compared to adenocarcinoma stomach, SRCC in the stomach occurs more often in women and younger patients. Patients with SRCC of the stomach show similar clinicopathological features to patients with undifferentiated histology. A recent study found that patients with SRCC had a better prognosis than patients with undifferentiated gastric carcinoma. However, when narrowed to patients with only advanced stage gastric cancer, those with SRCC had a worse prognosis than other cell types.
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In anatomy, a lobe is a clear anatomical division or extensionlobe at eMedicine Dictionary of an organ (as seen for example in the brain, lung, liver, or kidney) that can be determined without the use of a microscope at the gross anatomy level. This is in contrast to the much smaller lobule, which is a clear division only visible under the microscope.SIU SOM Histology GI Interlobar ducts connect lobes and interlobular ducts connect lobules.
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He became a lecturer in Histology and Embryology at the RVC in 1935. For the duration of World War II, the Royal Veterinary College was moved to the campus of the University of Reading. During this period, Amoroso collaborated with several other reproductive biologists. He was a founder member, in 1946, of the Society for Endocrinology; he would go on to become its Treasurer in 1956 and eventually Chairman from 1961 to 1966.
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The second method of histology processing is called frozen section processing. This is a highly technical scientific method performed by a trained histoscientist. In this method, the tissue is frozen and sliced thinly using a microtome mounted in a below-freezing refrigeration device called the cryostat. The thin frozen sections are mounted on a glass slide, fixed immediately & briefly in liquid fixative, and stained using the similar staining techniques as traditional wax embedded sections.
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It was originally responsible for the vermilion-, ochre-, and saffron-hued robes and mantles worn by Buddhist and Hindu monks. In medieval Ireland and Scotland, well-to-do monks wore a long linen undershirt known as a léine, which was traditionally dyed with saffron. In histology the hematoxylin-phloxine-saffron (HPS) stain and Movat's pentachrome stain are used as a tissue stain to make biological structures more visible under a microscope. Saffron stains collagen yellow.
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Historadiography is a technique formerly utilized in the fields of histology and cellular biology to provide semiquantitative information regarding the density of a tissue sample. It is usually synonymous with microradiography. This is achieved by layering a ground section of mineralized tissue (such as bone) with photographic emulsion on a glass slide and exposing the sample to a beam of X-rays. After developing the emulsion, the resulting radiograph can be viewed with a microscope.
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Osteocyte lacunae are oval-shaped and randomly distributed. Despite its tiny size, histology supports the idea that the Kongonaphon individual was not a hatchling or young juvenile. Parallel-fibered bone, lines of arrested growth, and flattened osteocyte lacunae are all correlated with the animal having been alive for quite some time prior to dying and becoming fossilized. The first characteristic in particular suggests that its growth was slower than early pterosaurs or dinosaurs.
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Russow was an authority on Sphagnaceae (sphagnum mosses) Botanical Gazette, Volume 24 By John Merle Coulter, et al and remembered for his research in plant anatomy and histology, in particular studies of the plant family Marsileaceae (aquatic and semi-aquatic ferns). Google Books, Marsileaceae The plant genus Russowia is named in his honor, CRC World Dictionary of Plant Names: Common Names, Scientific Names, Eponyms, by Umberto Quattrocchi as is Sphagnum russowii (Russow's sphagnum).
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Ultrastructure can also be viewed with scanning electron microscopy and super-resolution microscopy, although TEM is a standard histology technique for viewing ultrastructure. Such cellular structures as organelles, which allow the cell to function properly within its specified environment, can be examined at the ultrastructural level. Ultrastructure, along with molecular phylogeny, is a reliable phylogenetic way of classifying organisms. Features of ultrastructure are used industrially to control material properties and promote biocompatibility.
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This leads to inflammation, such as swelling, leading to rubbing of the heart on the pericardium. Day 4 through 7 are marked by “chronic inflammation”, on histology macrophages will be seen infiltrating the tissue. The role of these macrophages is the removal of necrotic myocytes. However, these cells are directly involved in the weakening of the tissue, leading to complications such as a ventricular free wall rupture, intraventricular septum rupture, or a papillary muscle rupture.
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Wayne O. Southwick was born in Lincoln, Nebraska in 1923. He received his undergraduate degree from the University of Nebraska in 1945 before attending the University of Nebraska College of Medicine, where he received his medical degree in 1947. While he was a student, Southwick served as an assistant in anatomy and histology. After interning at the Boston City Hospital, he moved to Baltimore where he had his residency at the Johns Hopkins Hospital.
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There were Filipino dentists who excelled in the field of dentistry during the Philippine-Republics era: among them were Dr. Victorino G. Villa and Dr. Luz C. Macapanpan. Villa became the Dean of the College of Dentistry of the University of the Philippines. Villa wrote an article about detino-enamel and other research papers that were published in the United States. On the other hand, Macapanpan focused her research regarding dental histology.
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Bertram J. Collingwood (1871–1936), a nephew of Lewis Carroll, was appointed professor of physiology and histology at University College Dublin in 1912. Collingwood, an Oxford graduate, was also a keen amateur footballer. He represented New College, Oxford and later played as a right half for Corinthians. Partly inspired by the recently inaugurated Sigerson and Fitzgibbon Cups, similar competitions for Gaelic football and hurling, Collingwood donated a trophy for an intervarsity association football competition.
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Micrograph of a GFAP immunostained section of a brain tumour. In biochemistry, immunostaining is any use of an antibody-based method to detect a specific protein in a sample. The term "immunostaining" was originally used to refer to the immunohistochemical staining of tissue sections, as first described by Albert Coons in 1941. However, immunostaining now encompasses a broad range of techniques used in histology, cell biology, and molecular biology that use antibody-based staining methods.
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The differential diagnosis includes many tumoral and nontumoral pathologies. A main concern is to differentiate early myositis ossificans from malignant soft-tissue tumors, and the latter is suggested by a fast-growing process. If clinical or sonographic findings are dubious and extraosseous sarcoma is suspected, biopsy should be performed. At histology, detection of the typical zonal phenomenon is diagnostic of myositis ossificans, though microscopic findings may be misleading during the early stage.
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"Effect of honey on testicular functions in rats exposed to Octaylphenol" .life science. vol 10(1) p979- 984 # Nesreen A. Rajeh, Nick Plant, Samar M. Al Saggaf, Hamdy A. Aly, Nasra N. Ayuob and Sufian M. ElAssouli (2012). "Acrylamide-mediated subacute testicular and genotoxicity, is it reversible." The Egyptian Journal of Histology, 35:424-436, 40 (1359-2012). # Samar M. Alsaggaf, Ghada A. Abdel-Hamid, Magda Hagras and Hamid A. Saleh (2012).
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Chamberlin's work includes more than 400 publications spanning over 60 years. The majority of his research concerned the taxonomy of arthropods and other invertebrates, but his work also included titles in folklore, economics, anthropology, language, botany, anatomy, histology, philosophy, education, and history. He was a member of the American Society of Naturalists, Torrey Botanical Club, New York Academy of Sciences, Boston Society of Natural History, Biological Society of Washington, and the Utah Academy of Sciences.
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In 1893 he became professor of histology at the university of Kharkov, and was later appointed director of education in . In 1897 he described the endocrine cells of the small intestine which now bear his name (Kulchitsky cells). In 1906 Kulchitsky was a member of council of Kharkov branch of The Union of Russian People. In 1916 he was appointed Minister of Education of the Russian Empire, a post he held until the February Revolution.
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In 1885 he published a pamphlet on Sounding for Gall Stones, and in the following year a work on Inflammation of the Liver, in which he advocated puncture of the capsule in congestive liver induration, and 'hepatic phlebotomy' for acute hepatitis. In 1868 his old pupil, George T. Brown, brought out a book on Histology, of demonstrations which Harley had given at University College. The second edition of the book Dr. Harley edited himself.
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Dogiel lived and worked in isolation, rarely but authoritatively publishing lengthy and richly illustrated articles. His work focused on degenerative and regenerative neuromuscular junction abnormalities, neuromuscular spindles, and various cellular categories within the central nervous system. He demonstrated a mastery of silver staining techniques and some of his illustrations contain a level of detail comparable to that which can be obtained using a low-power electronic microscope. Dogiel was an important figure in Russian histology.
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Radiologic osteosclerosis and histology are the main diagnostic features. Diagnosis can often be difficult because of the rareness of ECD as well as the need to differentiate it from LCH. A diagnosis from neurological imaging may not be definitive. The presence of symmetrical cerebellar and pontine signal changes on T2-weighted images seem to be typical of ECD, however, multiple sclerosis and metabolic diseases must also be considered in the differential diagnosis.
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This tissue cross-section demonstrates the gross pathology of polycystic kidneys. Renal pathology is a subspecialty of anatomic pathology that deals with the diagnosis and characterization of disease of the kidneys. In a medical setting, renal pathologists work closely with nephrologists and transplant surgeons, who typically obtain diagnostic specimens via percutaneous renal biopsy. The renal pathologist must synthesize findings from traditional microscope histology, electron microscopy, and immunofluorescence to obtain a definitive diagnosis.
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Douglass's early education was in the Medford public schools and the Pillsbury Academy in Owatonna, Minnesota, where he studied geology, paleontology, osteology, and mammalian anatomy. Later at the Shaw School of Botany at Washington University, he studied systematic botany and plant histology. Douglass received his master's of Science at the University of Montana in 1899. The following year at Princeton University he held a fellowship in biology, and he was granted a fellowship in geology.
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The course of study lasts 6 years or 12 semesters. During the first 3 years, students are engaged in pre-clinical courses (Anatomy, Histology, Chemistry, Physics, Cell Biology, Genetics, Physiology, Biochemistry, Immunology, Pathologic Physiology And Anatomy, Pharmacology, Microbiology, etc.). Contact with patients begins at the third year. The remaining 3 years are composed of rotations at various departments, such as Internal Medicine, Neurology, Radiology, Dermatology, Psychiatry, Surgery, Pediatrics, Gynecology and Obstetrics, Anesthesiology, and others.
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The ability to view and characterize different neural cells including microglia began in 1880 when Nissl staining was developed by Franz Nissl. Franz Nissl and F. Robertson first described microglial cells during their histology experiments. The cell staining techniques in the 1880s showed that microglia are related to macrophages. The activation of microglia and formation of ramified microglial clusters was first noted by Victor Babeş while studying a rabies case in 1897.
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Between his studies in Bonn, Harrison taught morphology at Bryn Mawr College with T. H. Morgan from 1894-1895. He was an instructor at Johns Hopkins University from 1896-1897 and became an associate at the university from 1897-1899. From 1899 until 1907, he was the Associate Professor of Anatomy, teaching histology and embryology. By this time he had contributed more than twenty papers and made the acquaintance of many leading biologists.
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Astraspids are characterized by a dermal ornamentation of large, mushroom shaped tubercles of fine-tubuled dentine ("astraspidine"), covered with a thick, glassy cap of enameloid.Sansom, I. J. and Smith, P. (in press). Astraspis - The anatomy and histology of an Ordovician fish. Palaeontology. Astraspids and eriptychiids were the first Ordovician vertebrates ever discovered in the 19th century, and they have long been the only known Ordovician vertebrates, until the discovery of the arandaspids, in the 1970s.
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It is important to also note that chemicals sometimes have several different names, and do not always appear on labels. The distinction between the various types of contact dermatitis is based on a number of factors. The morphology of the tissues, the histology, and immunologic findings are all used in diagnosis of the form of the condition. However, as suggested previously, there is some confusion in the distinction of the different forms of contact dermatitis.
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In this he followed the opinions of contemporary English gynaecologists. As he was not aware of physiological histology, he nearly always found signs of inflammation. He treated this with curettage and drastic caustics, sometimes after using a dilation knife (hysterotome) for the cervix. At the turn of the twentieth century Dutch gynaecologists such as Treub and Nijhoff began to cast doubt on such theories of "reflex neurosis", but Mendes de Leon persisted in his views.
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Mouse skin, stained with Haematoxylin (purple) and Eosin (pink). Haematoxylin stain is commonly followed (or counterstained) with another histologic stain, eosin. When paired, this staining procedure is known as H&E; staining, and is one of the most commonly used combinations in histology. Haematoxylin is also a component of the Papanicolaou stain (or PAP stain) which is widely used in the study of cytology specimens, notably in the PAP test used to detect cervical cancer.
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Her father worked as a doctor in New York City and was successful enough to let her family live comfortably. In 1922, Menkin graduated from Cornell University with an undergraduate degree in histology and comparative anatomy. She attended Columbia University for her graduate program and earned a master's degree in genetics only one year after graduating from Cornell. She taught biology and physiology for a short period while setting her sights on medical school.
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Based on the specimens found from the family Nanhsiungchelyidae, researchers have been able to create cladograms based on their findings. Placement of Basilemys on where it should be in terms of the genera Nanhsiungchelys and Zangerlia. With close examination of shell histology, along with skull and neck proportions, it was determined that Basilemys is more closely related to Zangerlia. Based on similar characteristics, a group that seems to be closely related to Basilemys is Adocus.
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Mohs' technique was later modified by Perry Robins in the 1970s, using fresh-tissue frozen histology. Rather than using the anesthetic Mohs paste, local anesthetic is used. The fresh skin specimen is then mounted on a cryostat, and frozen sections are examined instead of the Mohs paste-fixed sections. This method is now commonly referred to as Mohs surgery, and occasionally chemosurgery, in reference to the Mohs paste that Mohs initially used.
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William A. Wimsatt (born July 28, 1917 – died, January 9, 1985) was professor of Zoology and Chairman of the Department of Zoology at Cornell University. From 1945 until 1960, Wimsatt taught courses in histology and embryology in the College of Arts and Sciences and also in the New York State College of Veterinary Medicine. He was well known for his pioneering research on the interrelationships of hibernation and reproduction and the biology of bats.
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Upon organization, Johnson was named President of the Faculty and Professor of Materia Media & Therapeutics. The next year he chaired the Physiology and Histology departments, then the General Pathology and Public Hygiene departments in 1864. That winter, his health failed again and despite a six-month sabbatical in Europe, Johnson was forced to retire from his professorship and department presidency. The board of trustees then immediately elected him president of the board.
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Further study of the poorly preserved fossil material showed that these "plates" were in fact more likely to be fragments of ribs and hip bones. This reassessment was reaffirmed subsequently by histology of the purported osteoderms, which do not match the internal structure of other titanosaurian osteoderms. The fragmentary hip bone was tentatively identified as part of the ilium. Aside from the supposed armor, very little has been described of the anatomy of Agustinia.
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He also did research in neuropathology and published textbooks in anatomy and histology, and published three books based on Olof Larssell's work after Larssell died. During the Second World War, Jansen participated in the Norwegian resistance movement from 1940 onwards. He edited the illegal newspaper Bulletinen from 1941; from 1942 to 1944 as the sole editor, and was a member of the so-called Coordination Committee ( (KK)). He had to flee to Sweden in 1944.
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In 1903, he enrolled in Fukuoka Medical College in Fukuoka, a branch of the newly-established Kyushu University. He was amongst the first medical graduates when he graduated in 1907. He then entered the First Surgical Bureau and studied medicine under the direction of Professor (1867–1945), the first Japanese neurosurgeon. While working on his M.D. thesis, he examined four histology samples from surgically excised thyroids and described his findings as 'struma lymphomatosa'.
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The specimen was generally oval in cross-section. The protective bony plates covering the animal were composed of aspidin (chemically similar to modern shark's teeth), covered by tubercles composed of dentine.Sansom IJ, Smith MP, Smith MM and Turner P (1997) "Astraspis: The anatomy and histology of an Ordovician fish" Palaeontology, 40 (3): 625–642. It is from these tubercles (which are generally star-shaped) that the name 'Astraspis' (literally "star- shield") is derived.
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The remaining seven infected bats were PCR-positive with normal wing histology. Infected bats with WNS had higher proportions of lean tissue mass to fat tissue mass than uninfected bats in measuring an increase in total body water volume as a percent of body mass. Infected bats used twice as much energy as healthy bats, and starved to death. Direct calculations of energy expenditure failed for most bats, because isotope concentrations were indistinguishable from background.
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John Birkett, F.R.C.S. F.L.S. (1815–1904) was an English surgeon and member of the Linnean Society of London who was an early specialist on breast disease, including breast cancer, and an early advocate of histology. He published a book on breast disease in the mid-nineteenth century. Birkett was born near London in 1815. He was an apprentice to Bransby Cooper, a nephew of Astley Cooper, and like him a surgeon at Guy's Hospital.
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It has long striated ducts and short intercalated ducts.Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 135 The secretory acinar cells of the submandibular gland have distinct functions. The mucous cells are the most active and therefore the major product of the submandibular glands is saliva which is mucoid in nature. Mucous cells secrete mucin which aids in the lubrication of the food bolus as it travels through the esophagus.
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Brodie received his MS (Master of Science) degree in anatomy and histology from the University in 1934, and his PhD in anatomy in 1940. At the time of his death on January 2, 1976, Brodie was writing his own book on orthodontics. In 2004, The Dentofacial Complex (UIC College of Dentistry Press) was published after being completed by alumni, faculty, and staff of the University of Illinois at Chicago College of Dentistry.
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He graduated with his Bachelor of Medicine and Bachelor of Surgery (MBBS) degrees in 1932, and did his residency at Melbourne Hospital. Ford became a lecturer in anatomy at the university in 1933, and became a senior lecturer in anatomy and histology in 1934. While there he met Frederic Wood Jones, who shared and encouraged a passion for books. Ford would later dedicate his Bibliography of Australian Medicine 1790–1900 to Jones.
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HIVAN is the third most common cause of end stage kidney failure among African Americans, and commonly seen in African-American patients with HIV compared to other ethnic groups. In the USA 12% of patients dying with AIDS have histologically proven HIVAN, the worldwide incidence amongst AIDS patients appears to be similar. A South African study at Tygerberg Hospital, Stellenbosch University, has shown HIVAN histology in 33/61(54%) biopsies performed in HIV positive patients.
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While being Dean at Oregon Health & Science University School of Dentistry, Dr. Noyes introduced the "Vertical Curriculum" for dental students. He allowed first-year dental students to construct full dentures and participate in exercise of tooth morphology. This made a profound impact in dental education, as this curriculum was widely accepted and implemented in other dental schools. He also co-authored a textbook with his father, Oral Histology and Embryology with Laboratory Directions.
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Working under the guidance of his mentor, Ludwig Aschoff, Tawara performed a histological examination of 150 hearts with myocarditis (which led to the discovery of Aschoff bodies), and he began examining the atrioventricular bundle before embarking on a comprehensive study of the anatomy and histology of the heart's conduction system. The implications of his work were immediately recognized by Aschoff, who arranged for it to be published in the form of a monograph.
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Eastman, JT; Lannoo, MJ. (2011). Divergence of brain and retinal anatomy and histology in pelagic Antarctic notothenioid fishes of the sister taxa Dissostichus and Pleuragramma. Journal of Morphology 272:419-441. Since ice covers the surface of the ocean where Antarctic toothfish occur even in summer, these sensory specializations likely evolved to enable survival in the reduced light levels found under ice and in the Antarctic winter, as well as at deep depths.
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The key instrument for cryosection is the cryostat, which is essentially a microtome inside a freezer. The microtome can be compared to a very accurate "deli" slicer, capable of slicing sections as thin as 1 micrometre. The usual histology slice is cut at 5 to 10 micrometres. The surgical specimen is placed on a metal tissue disc which is then secured in a chuck and frozen rapidly to about –20 to –30 °C.
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Elected a Fellow of Downing College in 1880, Hill lectured on the histology and anatomy of the brain. He was Hunterian Professor at the Royal College of Surgeons from 1884 to 1885. He was Master of Downing College from 1888 to 1907 and Vice-Chancellor of the university from 1897 to 1899. As Vice-Chancellor, he startled some critics by inviting the actor Sir Henry Irving to deliver the Rede Lecture in 1898.
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He taught at Columbia from 1902, initially as an instructor in histology. He was State Deputy Health Commissioner from 1914 to 1917, and was offered the post of State Health Commissioner in 1930 by Governor Roosevelt, but turned it down. He was a first lieutenant in the Medical Reserve Corps from 1917, visiting France, and soon was promoted to Major and then to Lieutenant Colonel in the Medical Corps. He left the army in 1919.
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In humans, very little histology data are available, so a relationship between ochratoxin A and renal cell carcinoma has not been found. However, the incidence of transitional cell (urothelial) urinary cancers seems abnormally high in Balkan endemic nephropathy patients, especially for the upper urinary tract. The molecular mechanism of ochratoxin A carcinogenicity has been under debate due to conflicting literature, however this mycotoxin has been proposed to play a major role in reducing antioxidant defenses.
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Rosettes in Ependymoblastoma histology Further classification types have come up but not yet approved by the World Health Organization. The term "embryonal tumor with abundant neuropil and true rosettes", or ETANTR, has been proposed as a sixth subtype of PNET. However, the still unofficial term "embryonal tumor with multilayered rosettes" (ETMR) has been more frequently used and encompasses ETANTRs, medulloepitheliomas, ependymoblastomas, and variants of PNETs with presence of rosettes and with no well defined classification.
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Medical school typically consists of four years of education and training, although a few programs offer three-year tracks. Traditionally, the first two years consist of basic science and clinical medicine courses, such as anatomy, biochemistry, histology, microbiology, pharmacology, physiology, cardiology, pulmonology, gastroenterology, endocrinology, psychiatry, and neurology. DO students also study Osteopathic Manipulative Medicine. USMLE Step 1/COMLEX Level 1 of the medical licensing boards are taken at the completion of the preclinical phase of study.
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"Bone histology of dinosaurs from Dinosaur Cove, Australia", Journal of Vertebrate Paleontology 16(Supplement to No.3), 28A A possible Timimus hermani or related form from the Strzelecki Group near Inverloch, Victoria left a fossil of the first phalanx of its third toe with a depressed fracture on the plantar surface.Molnar, R. E., 2001, Theropod paleopathology: a literature survey: In: Mesozoic Vertebrate Life, edited by Tanke, D. H., and Carpenter, K., Indiana University Press, p. 337-363.
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He worked as a professor in Tartu (Dorpat) for 25 years and also started the anatomy collection of the University of Tartu. In his studies involving the embryonic development of birds and mammals, Rauber is credited with combining comparative embryology and histology with phylogenetic analysis. The eponymous "Rauber's layer" bears his name, being defined as a trophoblastic membrane over the embryonic disk in developing animals.Mondofacto Dictionary Definition of eponym He is buried to the Uus-Jaani cemetery in Tartu.
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Long-bone histology enables researchers to estimate the age that a specific individual reached. A study by Griebeler et al. (2013) examined long bone histological data and concluded that the unnamed mamenchisaurid SGP 2006/9 weighed , reached sexual maturity at 20 years and died at age 31.Griebeler EM, Klein N, Sander PM (2013) Aging, Maturation and Growth of Sauropodomorph Dinosaurs as Deduced from Growth Curves Using Long Bone Histological Data: An Assessment of Methodological Constraints and Solutions.
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Life restoration of Lourinhanosaurus based on ML 370 and skeletal reconstructions L. antunesi was rather large. The individual found was a sub-adult, measuring some 4.5 m in length and weighing around 160 kg. Histology shows that the holotype specimen was between 14 and 17 years old. Though gastroliths have been found in other theropods since the description of L. antunesi, this was the first theropod dinosaur for which this kind of remains have been assigned.
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Microscopy with UV Surface Excitation (MUSE) is a novel microscopy method that utilize the shallow penetration of UV photons (230–300 nm) excitation.Farzad Fereidouni, Ananya Datta Mitra, Stavros Demos, Richard Levenson, "Microscopy with UV Surface Excitation (MUSE) for slide-free histology and pathology imaging," Proc. SPIE 9318, Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis, 93180F (11 March 2015).Fereidouni, F., Harmany, Z. T., Tian, M., Todd, A., Kintner, J. A., Mcpherson, J. D., . . .
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Standard excision is still being done by most surgeons. Unfortunately, the recurrence rate is exceedingly high (up to 50%). This is due to the ill- defined visible surgical margin, and the facial location of the lesions (often forcing the surgeon to use a narrow surgical margin). The narrow surgical margin used, combined with the limitation of the standard "bread-loafing" technique of fixed tissue histology – result in a high "false negative" error rate, and frequent recurrences.
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Masson's trichrome staining on rat trachea. Hematoxylin and eosin (H&E; stain) is one of the most commonly used stains in histology to show the general structure of the tissue. Hematoxylin stains cell nuclei blue; eosin, an acidic dye, stains the cytoplasm and other tissues in different stains of pink. In contrast to H&E;, which is used as a general stain, there are many techniques that more selectively stain cells, cellular components, and specific substances.
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Santiago Ramón y Cajal in his laboratory. In the 17th century the Italian Marcello Malpighi used microscopes to study tiny biological entities; some regard him as the founder of the fields of histology and microscopic pathology. Malpighi analyzed several parts of the organs of bats, frogs and other animals under the microscope. While studying the structure of the lung, Malpighi noticed its membranous alveoli and the hair-like connections between veins and arteries, which he named capillaries.
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See this site for excerpts. Sometime around 1879, J. Leon Williams began a two-year apprenticeship by a Dr. Roberts in North Vassalboro, Maine and later began practicing in the same town. Williams later passed examinations for the DDS degree at the Baltimore College of Dental Surgery and the equivalent LDS degree in Ireland. He joined the Maine Dental Society and used the opportunity to borrow their microscope to study the histology and pathology of tooth enamel.
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CellNetix Pathology & Laboratories, LLC, headquartered in Seattle, Washington, is a premier anatomic pathology provider in the Pacific Northwest, with 50 physicians and more than 300 total staff. Services include cytology, histology, fine needle aspiration (FNA) services, flow cytometry, immunohistochemistry, immunofluorescence, UroVysion™, and molecular diagnostics. CellNetix institutes pollution prevention planning“CellNetix Pathology and Laboratories -Reducing, Reusing, Recycling….. and Saving Money” Department of Ecology State of Washington and receives technical assistance from Washington State Department of Ecology.
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Full-coverage crowns are sometimes being used to compensate for the abraded enamel in adults, tackling the sensitivity the patient experiences. Usually stainless steel crowns are used in children which may be replaced by porcelain once they reach adulthood.Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 64 These aid with maintaining occlusal vertical dimension. Aesthetics may be addressed via placement of composite or porcelain veneers, depending on patient factors e.g. age.
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Nile blue (or Nile blue A) is a stain used in biology and histology. It may be used with live or fixed cells, and imparts a blue colour to cell nuclei. It may also be used in conjunction with fluorescence microscopy to stain for the presence of polyhydroxybutyrate granules in prokaryotic or eukaryotic cells. Boiling a solution of Nile blue with sulfuric acid produces Nile red (Nile blue oxazone). ppm, 100 ppm, 10 ppm, 1 ppm, 100 ppb.
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The two disorders also have other differences: the histology of the involved tissues in FA-DLBCL and DLBCL-CI are dissimilar and the large EBV+ B cells in FA- DLBCL, unlike those in DLBCL-CI, do not overexpress the Myc gene and have relatively few karyotype chromosomal abnormalities. Patients with FA-DLBCL present with signs and symptoms reflecting the location of the infiltrative lesion. When these lesions occupy the heart (e.g. on myxommas or prosthetic valves) or vasculature (e.g.
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PAS diastase showing the fungus Histoplasma. Periodic acid-Schiff is a histology special stain used to mark carbohydrates (glycogen, glycoprotein, proteoglycans). PAS is commonly used on liver tissue where glycogen deposits are made which is done in efforts to distinguish different types of glycogen storage diseases. PAS is important because it can detect glycogen granules found in tumors of the ovaries and pancreas of the endocrine system, as well as in the bladder and kidneys of the renal system.
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Rescuing the tapinocephalids from a life of diluvian swamp-wallowing, Bakker (1975, 1986) argued that bone histology, geographic distribution, and predator-prey relationships showed that these were active, fully terrestrial and at least partially endothermic animals, midway between the ectothermic pelycosaurs and the fully endothermic theriodonts. Others like McNab and Geist suggest that the tapinocephalids were better considered inertial homeotherms, with the large barrel-like body and short tail being the most efficient surface for conserving heat.
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He studied at Charles University in Prague followed by studies in embryology and histology at Berlin. He published a monograph on the Thysanoptera in 1895. In 1905 he was made a special member of the Royal Czech Academy. Uzel worked briefly at the State Botanical Garden in Peradenia, Ceylon (Sri Lanka) followed by work on plant pathology at the sugar beet production research station in Prague and as a professor at the Czech Technical College from 1920.
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Stereology is the three-dimensional interpretation of two-dimensional cross sections of materials or tissues. It provides practical techniques for extracting quantitative information about a three-dimensional material from measurements made on two-dimensional planar sections of the material. Stereology is a method that utilizes random, systematic sampling to provide unbiased and quantitative data. It is an important and efficient tool in many applications of microscopy (such as petrography, materials science, and biosciences including histology, bone and neuroanatomy).
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Diatoms can be obtained from multiple sources.Chamberlain, C. J. (1901) Methods in Plant Histology, University of Chicago Press, USA Marine diatoms can be collected by direct water sampling, and benthic forms can be secured by scraping barnacles, oyster and other shells. Diatoms are frequently present as a brown, slippery coating on submerged stones and sticks, and may be seen to "stream" with river current. The surface mud of a pond, ditch, or lagoon will almost always yield some diatoms.
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Laboratory data demonstrate abnormally elevated levels of serum gamma globulin and/or IgG, or the presence of autoantibodies. ::III. Histopathologic examination of the pancreas shows fibrotic changes with lymphocyte and plasma cell infiltrate. For diagnosis, criterion I (pancreatic imaging) must be present with criterion II (laboratory data) and/or III (histopathologic findings). Mayo Clinic has come up with five diagnostic criteria called HISORt criteria which stands for histology, imaging, serology, other organ involvement, and response to steroid therapy.
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The dental program was formed in 1901, during the presidency of Jerome Daugherty, with the acquisition by Georgetown of the Washington Dental College and Hospital of Oral Surgery on Massachusetts Avenue. The Washington Dental College were incorporated into the School of Medicine as the dental department. There were initially five faculty chairs of: techniques and orthodontia; dental histology and pathology; operative dentistry; oral surgery; and prosthetic dentistry. Dr. William N. Cogan was elected as the school's first dean.
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Cystadenocarcinoma is a malignant form of a cystadenoma and is a cancer derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. The neoplastic cells manifest varying degrees of anaplasia and invasiveness, and local extension and metastases occur. Cystadenocarcinomas develop frequently in the ovaries, where pseudomucinous and serous types are recognized. Similar tumor histology has also been reported in the pancreas, although it is a considerably rarer entity representing 1 - 1.5% of all Pancreatic cancer.
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Phosphotungstic acid-haematoxylin staining demonstrating contraction band necrosis in an individual that had a myocardial infarction (heart attack). Phosphotungstic acid haematoxylin (PTAH) is a mix of haematoxylin with phosphotungstic acid, used in histology for staining. It stains some tissue in contrasting colors in a way similar to haematoxylin and eosin stain, as phosphotungstic acid binds to tissue proteins. It is used to show gliosis in the central nervous system, tumours of skeletal muscles, and fibrin deposits in lesions.
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Phosphotungstic acid is used in histology for staining specimens, as a component of phosphotungstic acid haematoxylin, PTAH, and “trichrome” reagents, and as a negative stain for imaging by a transmission electron microscope. ;Phosphotungstic acid haematoxylin (PTAH) :Mallory described the reagent now generally known as PTAH in 1897. PTAH stains tissues either reddish brown or blue depending on their type. This property of simultaneously staining two different colours is different from other haematoxylin reagents e.g. alum-haematoxylin.
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After the biopsy is performed, the sample of tissue that was removed from the patient is sent to the pathology laboratory. A pathologist specializes in diagnosing diseases (such as cancer) by examining tissue under a microscope. When the laboratory (see Histology) receives the biopsy sample, the tissue is processed and an extremely thin slice of tissue is removed from the sample and attached to a glass slide. Any remaining tissue is saved for use in later studies, if required.
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In 1889 he became a lecturer in Bonn, and in 1896 relocated to the Polytechnic Institute of Darmstadt, where he was appointed director of the botanical garden. Schenck undertook important research involving adaptation of water plants to their underwater environment. He also conducted studies on the ecology, morphology and histology of lianas. In 1886-87 he accompanied Andreas Franz Wilhelm Schimper (1856–1901) on a scientific expedition to Brazil, and in 1908 performed botanical investigations in Mexico.
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Rudolf Virchow (1821-1902) is generally recognized to be the father of microscopic pathology. While the compound microscope had been invented approximately 150 years prior, Virchow was one of the first prominent physicians to emphasize the study of manifestations of disease which were visible only at the cellular level. Rudolf Virchow at Whonamedit.com A student of Virchow's, Julius Cohnheim (1839-1884) combined histology techniques with experimental manipulations to study inflammation, making him one of the earliest experimental pathologists.
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II. Teil. Uber die funktionelle Struktur der menschlichen Stimmlippen mit besonderer Beruecksichtigung des elastischen Gewebes. [Contributions to the histology of humans, Part II: On the functional structure of the human vocal folds with special consideration of the elastic tissue] Anat Hefte, 9 (1897), pp. 103–107 Besides the superficial lamina propria of the vocal fold, Reinke's other eponym is attached to crystals found in Leydig cells of the human testes and hilar cells of the human ovary.
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Acidophile (or acidophil, or, as an adjectival form, acidophilic) is a term used by histologists to describe a particular staining pattern of cells and tissues when using haematoxylin and eosin stains. Specifically, the name refers to structures which "love" acid, and take it up readily. More specifically, acidophilia can be described by cationic groups of most often proteins in the cell readily reacting with acidic stains.Ross MH, Pawlina W. Histology : a text and atlas. 5. ed.
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Ugo Cerletti was born in Conegliano, in the region of Veneto, Italy, on 26 September 1877. He studied Medicine at Rome and Turin, later specializing in neurology and neuropsychiatry. In his early scientific studies, Cerletti mainly focused on common issues in the fields of histology and histopathology. He demonstrated how the nervous tissue reacts to different pathogenic stimuli in its own ways, making the histopathology of nervous tissue an independent category in the study of medicine.
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From 1903 to 1904, he was a resident at the Clinic of Internal Medicine under Carl Wilhelm Hermann Nothnagel. Subsequently, he travelled through Europe for two years and worked for several scientists. He studied neurology, histology, and psychiatry in Paris (under Alexis Joffroy, Valentin Magnan and Pierre Marie). In Nancy, he was introduced to hypnosis (under Hippolyte Bernheim); in Strasbourg he became familiar with methods of microscopic research of the nervous system (under Albrecht von Bethe).
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He was born in 1920, in Budapest, Hungary. His father was an engineer at the Budapest Waterworks until the Communist takeover after World War II. He graduated from the University of Budapest in 1942 and started his research career at the Department of Histology and Embryology of the university. In 1947, he continued his research at the Karolinska Institutet in Stockholm. He was the director of ophthalmic research at Columbia-Presbyterian Medical Center, from 1975 to 1982.
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Illustrated Anatomy of the Head and Neck, Fehrenbach and Herring, Elsevier, 2012, p. 156 The sublingual glands are drained by 8-20 excretory ducts called the ducts of Rivinus.Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 255 The largest of all, the sublingual duct (of Bartholin) joins the submandibular duct to drain through the sublingual caruncle. The sublingual caruncle is a small papilla near the midline of the floor of the mouth on each side of the lingual frenum.
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At Pavia, he introduced microscopic studies in the fields of anatomy and histology, being credited with developing systematic studies of cell structure via the microscope. He conducted pioneer physiological studies on salivation, and described "Oehl's muscles", defined as strands of muscle fibers in the chordae tendineae of the left atrioventricular valve.Mondofacto Dictionary (definition of eponym) Among his better known students were Camillo Golgi (1843-1926), Camillo Bozzolo (1845-1920), Giulio Bizzozero (1846-1901) and Enrico Sertoli (1842-1910).
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A medical laboratory or clinical laboratory is a laboratory where tests are done on biological specimens in order to get information about the health of a patient. Such laboratories may be divided into categorical departments such as microbiology, hematology, clinical biochemistry, immunology, serology, histology, cytology, cytogenetics, or virology. In many countries, there are two main types of labs that process the majority of medical specimens. Hospital laboratories are attached to a hospital, and perform tests on these patients.
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Moreover, even though hamartomas show a benign histology, there is a risk of some rare but life-threatening complications such as those found in neurofibromatosis type I and tuberous sclerosis. It is different from choristoma, a closely related form of heterotopia. The two can be differentiated as follows: a hamartoma is an excess of normal tissue in a normal situation (e.g., a birthmark on the skin), while a choristoma is an excess of tissue in an abnormal situation (e.g.
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A child of an Echigo Nagaoka clansman, he graduated from East School,, which was the school existed in Meiji era in Japan. the precursor of the Tokyo Imperial University medical school, in 1880. He then went to Germany where he learned anatomy and histology. He returned to Japan in 1885, and in the following year he was appointed a professor at Tokyo Imperial University Medical School, becoming the first Japanese lecturer on anatomy in the school.
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Once suspected, the diagnosis of blastomycosis can usually be confirmed by demonstration of the characteristic broad based budding organisms in sputum or tissues by KOH prep, cytology, or histology. Tissue biopsy of skin or other organs may be required in order to diagnose extra-pulmonary disease. Blastomycosis is histologically associated with granulomatous nodules. Commercially available urine antigen testing appears to be quite sensitive in suggesting the diagnosis in cases where the organism is not readily detected.
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The alveolar crest is the most cervical rim of the alveolar bone proper. In a healthy situation, the alveolar crest is slightly apical to the cementoenamel junction (CEJ) by approximately 1.5 to 2 mm. The alveolar crests of neighboring teeth are also uniform in height along the jaw in healthy situation.Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 176 The supporting alveolar bone consists of both cortical bone and trabecular bone.
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UCD is diagnosed based on patient history, physical exam, laboratory testing, radiologic imaging, and microscopic analysis (histology) of biopsied tissue from an enlarged lymph node. There are no widely accepted diagnostic criteria for UCD; however, diagnosis generally requires enlargement of lymph nodes limited to a single region of lymph nodes (typically confirmed with radiologic imaging), biopsy of an enlarged lymph node demonstrating characteristic features of Castleman disease, and exclusion of other diseases that can mimic UCD.
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On 19 February 1912 he died of tuberculosis at age 35. Negri performed extensive research in the fields of histology, hematology, cytology, protozoology and hygiene. In 1903 he discovered the eponymous Negri bodies, defined as cytoplasmatic inclusion bodies located in the Purkinje cells of the cerebellum in cases of rabies in animals and humans. He documented his findings in an article titled Contributo allo studio dell'eziologia della rabia, published in the journal Bollettino della Societa medico-chirurgica.
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Lombroso was a renowned scientist in medical psychology such as genius, madness and criminality. Inspired by Lombroso, Golgi wrote a thesis on the etiology of mental disorders, from which he obtained his M.D. in 1868. He became more interested in experimental medicine, and started attending the Institute of General Pathology headed by Giulio Bizzozero. Three years his junior, Bizzozero was an eloquent teacher and experimenter, who specialised in histology of the nervous system and the properties of bone marrow.
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The portal triad, consists of the hepatic artery, the portal vein, and the common bile duct. The triad may be seen on a liver ultrasound, as a Mickey Mouse sign with the portal vein as the head, and the hepatic artery, and the common bile duct as the ears. Histology, the study of microscopic anatomy, shows two major types of liver cell: parenchymal cells and nonparenchymal cells. About 70–85% of the liver volume is occupied by parenchymal hepatocytes.
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Moreover, students receive an extensive laboratory training in human anatomy, general chemistry, biochemistry, microbiology, histology, physiology and pathology .Students have access to patients in their clinical class. Using the most advanced methods and technology, students learn classical techniques of manipulation with real objects. They sample tissues for histological research, prepare corpses to refine surgical skills in the courses of normal anatomy and operative surgery, work with laboratory animals for experiments in the courses of pathological physiology, pharmacology, etc.
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The olfactory receptor neurons are sensory neurons of the olfactory epithelium. They are bipolar neurons and their apical poles express odorant receptors on non-motile cilia at the ends of the dendritic knob, which extend out into the airspace to interact with odorants. Odorant receptors bind odorants in the airspace, which are made soluble by the serous secretions from olfactory glands located in the lamina propria of the mucosa.Ross, MH, Histology: A Text and Atlas, 5th Edition.
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Prognosis of the CC is affected by age, stage, and histology as well as treatment The primary treatment is surgical. FIGO-cancer staging is done at the time of surgery which consists of peritoneal cytology, total hysterectomy, bilateral salpingo- oophorectomy, pelvic/para-aortic lymphadenectomy, and omentectomy. The tumor is aggressive and spreads quickly into the myometrium and the lymphatic system. Thus even in presumed early stages, lymphadenectomy and omentectomy should be included in the surgical approach.
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1903-1914, Tangle was appointed ordinarius in charge of medical chemistry at University of Budapest Chemistry Department following the death of the predecessor, Plósz Béla. From 1914-1917, he was regular professor of physiology at Budapest University. While there, he contributed significant research into the study of the development, bird embryo, energy and the metabolism of insects during metamorphosis. He was a founder of the College of veterinary medicine, Department of Physiology and Biochemistry, and Anatomy and Histology.
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Histology has also allowed the age of other specimens to be determined. Growth curves can be developed when the ages of different specimens are plotted on a graph along with their mass. A T. rex growth curve is S-shaped, with juveniles remaining under until approximately 14 years of age, when body size began to increase dramatically. During this rapid growth phase, a young T. rex would gain an average of a year for the next four years.
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Before attending medical school, he obtained master's degree on flounder (a type of flatfish), partly undertaken at Woods Hole Oceanographic Institution. He began at Harvard Medical School in 1898. In 1905, while an assistant in Pathology at Harvard, he studied the histology of the skin lesions in varicella, being the first to recognize inclusion bodies in varicella. In 1907, Tyzzer was a founder member of the American Association for Cancer Research, serving as its president from 1912–1913.
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Males have five sets of cloacal glands, the posterior most set being different in its morphology and histology, that may contribute an ability of the males to court and mate with multiple females in quick succession. This is due to the fact that multiple spermatophores would be produced at the same time, so males wouldn't have to waste extra energy producing another spermatophore after each mating session and consequently create a polygynous dynamic between the individuals.
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In 1802, Mirbel published his treatise Traité d'anatomie et de physiologie végétale which established his position as a founder of cytology, plant histology and plant physiology in France. He proposed that all plant tissue is modified from parenchyma (supporting tissue). His observation, in 1809, that each plant cell is contained in a continuous membrane, remains a central contribution to cytology. In 1803, Mirbel obtained the post of superintendent of the gardens of Napoleon's Château de Malmaison.
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CERN leads five research projects to discover new treatments for ependymoma. #Clinical Trials – CERN Foundation clinical trials test the efficacy of novel treatment approaches for ependymoma. This project serves as a testing ground for new diagnostic and drug discoveries made in Projects Two and Three."About CERN, Projects and Collaboration", 2012-09-06 #Tumor Profiling and Pathology – An integrated histology and molecular biology grading system is used to improve the accuracy of ependymoma diagnosis and prognostication.
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One of Mall's other goals was to raise the prestige of anatomists and the study of anatomy in America. During his tenure, anatomy was deemed as a basic science, a prerequisite for entering the highly respected surgical field. Mall's convictions led him to expand the anatomical curricula to include histology, histogenesis, and embryology. The collective research spearheaded by Mall and his coworkers at the Department of Anatomy demonstrated an impact comparable to that of the surgical field.
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The cutaneous manifestations of Birt–Hogg–Dubé were originally described as fibrofolliculomas (abnormal growths of a hair follicle), trichodiscomas (hamartomatous lesions with a hair follicle at the periphery, often found on the face), and acrochordons (skin tags). Cutaneous manifestations are confirmed by histology. Most individuals (89%) with BHD are found to have multiple cysts in both lungs, and 24% have had one or more episodes of pneumothorax. The cysts can be detected by chest CT scan.
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Colonoscopy with evaluation of the terminal ileum is the gold standard in the diagnosis of checkpoint inhibitor induced colitis. However, in most cases, a limited evaluation of the distal colon with flexible sigmoidoscopy is sufficient. Endoscopic findings may include loss of vascular pattern, erythema, edema, erosions, ulcers, exudates, granularity, and bleeding. Biopsies should be taken even in endoscopic findings are normal, as inflammation may not be immediately apparent and may only be seen on histology (microscopic colitis).
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The name "gentian violet" (or Gentianaviolett in German) is thought to have been introduced by the German pharmacist Georg Grübler, who in 1880 started a company in Leipzig that specialized in the sale of staining reagents for histology. The gentian violet stain marketed by Grübler probably contained a mixture of methylated pararosaniline dyes. The stain proved popular and in 1884 was used by Hans Christian Gram to stain bacteria. He credited Paul Ehrlich for the aniline-gentian violet mixture.
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Specimens of Ophiacodon vary greatly in size. These differences in size were once used to distinguish species, but are now recognized as ontogenetic variations related to the ages of individuals. Smaller bones often have more poorly developed joint surfaces than larger bones, implying that they come from juvenile individuals while the larger bones come from adults. Analysis of the histology or microscopic anatomy of bones suggests that differences in size represent different growth stages rather than different species.
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During the Second World War, he assisted in the outpatient department of UCH, and after the war he became active in postgraduate training of home and international dermatologists. In 1945 he was elected to the first readership in dermatological histology at UCH. He also wrote about numerous other skin conditions including amyloidosis, glomus tumour, mucin in granuloma annulare and Kaposi’s sarcoma. Encouragement and collaboration with dermatologist Geoffrey Dowling led to an interest in the relationship between dermatomyositis and scleroderma.
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He was born in the Moseley district of Birmingham on 23 December 1891 the son of Harriet Annie Purser (1862-1952) and her husband, George Jesse Purser (1853-1927). He studied natural sciences at the University of Cambridge graduating with an MA in 1915.Public Schools Year Book 1915 He immediately began lecturing in embryology and histology at the University of Glasgow moving to the University of Edinburgh around 1918. In 1920 he was elected a Fellow of the Royal Society of Edinburgh.
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The six standing at the window-side of the painting are (from right to left): Alix Joffroy (1844-1908), anatomical pathologist, neurologist and psychiatrist; Jean-Baptiste Charcot (1867-1936), Charcot's son, at the time a medical student and, later, a polar explorer; Mathias-Marie Duval (1844-1907), Professor of anatomy and histology; Georges Maurice Debove (1845-1920), later Dean of the medical school; Philippe Burty, art collector, critic, and writer; and Victor André Cornil (1837-1908), pathologist, histologist, and politician.
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CT scan of the chest revealing a large necrotic mass in the left anterior mediastinum (indicated by the red line). Histology later established the diagnosis of a thymoma. Another axial slice of a CT scan of the chest showing a small thymoma anterior to the heart (marked with the red line). When a thymoma is suspected, a CT/CAT scan is generally performed to estimate the size and extent of the tumor, and the lesion is sampled with a CT-guided needle biopsy.
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Colorectal PDX models are relatively easy to establish and the models maintain genetic similarity of primary patient tumor for about 14 generations. In 2012, a study established 27 colorectal PDX models that did not diverge from their respective human tumors in histology, gene expression, or KRAS/BRAF mutation status. Due to their stability, the 27 colorectal PDX models may be able to serve as pre-clinical models in future drug studies. Drug resistance studies have been conducted using colorectal PDX models.
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He was in general veterinary practice in Retford, Nottinghamshire. He succeeded his friend and colleague, John McFadyean, as Professor of Anatomy and Histology at the R(D)VC in 1892. In 1900 he was appointed as the first Principal of the Royal Veterinary College of Ireland at its new premises in Pembroke Road, Dublin. He was editor of the Veterinarian from 1895 until its last edition 1902 and held the George Heriot Research Fellowship in Science in the University of Edinburgh.
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Use of the term "pseudohermaphroditism" can be problematic, and is now considered redundant. The term "pseudohermaphroditism" was created by Edwin Klebs in 1876,Klebs, T. A. E. (1876). Handbuch der pathologischen Anatomie [Handbook of pathological anatomy]. Berlin: A. Hirschwald, long before the genetic roles of the X chromosome and Y chromosome and the social components of gender identity were well characterized, which is why the term is usually used to describe the dissonance between gonadal histology and external genital appearance.
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Two studies used genome sequencing independently to identify germline mutations in BAP1 in families with genetic predispositions to mesothelioma and melanocytic skin tumors The atypical melanocytic lesions resemble Spitz nevi and have been characterized as "atypical Spitz tumors" (ASTs), although they have a unique histology and exhibit both BRAF and BAP1 mutations. Further studies have identified germline BAP1 mutations associated with other cancers. These studies suggest that germline mutation of BAP1 results in a Tumor Predisposition Syndrome linking BAP1 to many more cancers.
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Primary colonic EMZL, also termed primary colonic MALT lymphoma, usually presents at an early stage of disease with evidence of lower GI tract bleeding (e.g. tarry bowel movements and/or iron deficiency anemia), less commonly with lower abdominal pain, and rarely with bowel perforation or intussusception. Endoscopic examination most often reveals a single polyp or rarely multiple polyps, a mucosal ulcer, or a mucosal nodule. Diagnosis is passed on biopsy of the lesions showing a histology typical of EMZL, e.g.
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After graduating from high school with a Baccalaureat, any student can register at a university of medicine (there are about 30 of them throughout the country). Until 2018, at the end of the first year, an internal ranking examination took place at each of these universities in order to implement the numerus clausus. This ranking examination and the numerus clausus has since been abolished. First year consists primarily of theoretical classes such as biophysics and biochemistry, anatomy, ethics or histology.
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Ruffer was naturalized as a British citizen in 1890. In 1891, he was appointed the first director of the British Institute of Preventive Medicine, latterly the Lister Institute. Moving to Egypt for health reasons, Ruffer was appointed a professor of bacteriology at The Faculty of Medicine, Cairo University in 1896, later taking roles on committees dealing with health, disease, and sanitation. In Egypt he worked on the histology of mummies publishing his findings and helping to establish the field of paleopathology.
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The first fossils identified in this order were discovered in the Middle Jurassic Gristhorpe bed of the Cloughton formation in Cayton Bay, Yorkshire – hence the name CAYTONiales. They have since been found in Mesozoic rocks all over world. It is likely that Caytoniales flourished in wetland areas, because they are often found with other moisture-loving plants such as horsetails in waterlogged paleosols. The first fossil Caytoniales were preserved as compressions in shale with excellent preservation of cuticles allowing study of cellular histology.
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The enamel on primary teeth has a more opaque crystalline form and thus appears whiter than on permanent teeth. The large amount of mineral in enamel accounts not only for its strength but also for its brittleness.Ten Cate's Oral Histology, Nanci, Elsevier, pages 70-94 Tooth enamel ranks 5 on Mohs hardness scale and has a Young's modulus of 83 GPa. Dentin, less mineralized and less brittle, 3–4 in hardness, compensates for enamel and is necessary as a support.
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Bhat, Mohd Shafi, Sanghamitra Ray, and PM DATTA. 2017 A New Hybodont Shark (Chondricthyes, Elasmbocranchii) from the Upper Triassic Tiki Formation of India with Remarks on its Dental Histology and Biostratigraphy. Journal of Paleontology, 92(2):221-239 It is overlain by the Parsoria Formation and is composed of pink, red, and lavender colors and interbeds of sandstone that contain clay clasts of varying size. The Tiki Formation is underlain by the Pali Formation with local erosional contact to the area of study.
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Upon graduating Pickerill worked in a dental practice in Hereford and as a clinical demonstrator in the dental department of the General Hospital in Birmingham. In 1906 he was appointed a lecturer in dental pathology and histology at the University of Birmingham. In 1906 he married Mabel Knott. In 1906 after seeing an advertisement he applied for and was appointed at the age of 28 to the position of first director of the Dental School at the University of Otago.
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It was about a meter long, the skull was over in length. It was a robust and stocky animal with a large head and stout backbone. Some researchers think it might have been semi-aquatic, with adaptations formerly thought to indicate digging habits now interpreted as speciation towards limb-powered swimming.Anusuya Chinsamy-Turan, Forerunners of Mammals: Radiation • Histology • Biology, Indiana University Press, 18/11/2011 Slight flattening and flaring of the tail vertebrae also suggest specialisms for a semi-aquatic ecology.
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Mixed tumors contain elements of more than one of the above classes of tumor histology. To be classed as a mixed tumor, the minor type must make up more than 10% of the tumor. Though mixed carcinomas can have any combination of cell types, mixed ovarian cancers are typically serous/endometrioid or clear cell/endometrioid. Mixed germ cell tumors make up approximately 25–30% of all germ cell ovarian cancers, with combinations of dysgerminoma, yolk sac tumor, and/or immature teratoma.
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LMP tumors have other abnormal features, including increased mitosis, changes in cell size or nucleus size, abnormal nuclei, cell stratification, and small projections on cells (papillary projections). Serous and/or mucinous characteristics can be seen on histological examination, and serous histology makes up the overwhelming majority of advanced LMP tumors. More than 80% of LMP tumors are Stage I; 15% are stage II and III and less than 5% are stage IV. Implants of LMP tumors are often non-invasive.
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He returned to the College of Physicians and Surgeons as instructor in histology (1893-1897), and clinical pathology (1897-1898). After a brief stint as a surgeon with the US Army, Ewing was appointed in 1899 the first professor of clinical pathology at the newly formed Medical College of Cornell University in New York, where he was the only full-time professor. In 1902, Ewing helped to establish one of the first funds for cancer research, endowed by Mrs. Collis P. Huntington.
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Alfred Kohn (22 February 1867 – 15 January 1959) was the head of the Institute of Histology at the Medical Faculty of German University in Prague for 26 years. He entered the history of medicine by discovery of the nature and origin of parathyroid glands and by pioneering research into chromaffin cells and sympathetic paraganglia. Kohn's papers on the pituitary, interstitial cells of testes, and ovaries are also related to endocrinology. All his studies are based on descriptive and comparative histological and embryological observations.
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Some people with NCGS may indeed have celiac disease. A 2015 systematic review found that 20% of people with NCGS presenting with HLA-DQ2 and/or HLA-DQ8 haplotypes, negative serology, and normal histology or duodenal lymphocytosis had celiac disease. The presence of autoimmune symptoms in people with NCGS suggests the possibility of undiagnosed celiac disease. Autoimmune diseases typically associated with celiac disease are diabetes mellitus type 1, thyroiditis, gluten ataxia, psoriasis, vitiligo, autoimmune hepatitis, dermatitis herpetiformis, primary sclerosing cholangitis, and others.
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In 1911 he was awarded his MD with a gold medal for his thesis Studies on Inflammation. He was unable to serve in World War I due to ill health, so taught pathology at the University of Edinburgh. Bruce died unexpectedly, and Dawson continued the research on his own. In 1916 he published a landmark paper on the histology of "disseminated sclerosis", describing the distribution and stages of lesions, reviewing theories on the aetiology and describing the inflammatory process seen in the disease.
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For his thesis, Contributions to the Chemistry and Physiology of Foetal Nutrition, he was awarded a gold medal. He did postgraduate studies in both Heidelberg and Leipzig in Germany. In 1867 he was elected a Fellow of the Royal Society of Edinburgh his proposer being Sir Andrew Douglas Maclagan. He taught in the Edinburgh Extramural School of Medicine, giving lectures on physiology and histology at Surgeon's Hall. Between 1863-1869 he was Physician to the Royal Hospital for Sick Children.
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Enamel spindles are "short, linear defects, found at the dentinoenamel junction (DEJ) and extend into the enamel, often being more prevalent at the cusp tips."Histology Course Notes: "Mature Enamel", New Jersey Dental School, 2003-2004, page 2. The DEJ is the interface of the enamel and the underlying dentin. Because they are "formed by entrapment of odontoblast processes between ameloblasts prior to and during amelogenesis," they cannot be found at the enamel surface protruding inward, as enamel lamellae are often located.
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In 1923 Bülbring entered the University of Bonn to study physiology hoping to eventually read medicine. Her enthusiasm for histology led her to work in the laboratory of Boeke, a renowned anatomist. The techniques she acquired during this working period became the basis for her work of her first publication and doctorate in medicine. Bülbring spent a year in Munich focusing on internal medicine, paediatrics and surgery attracted by the reputation of Friedrich von Müller, a Professor of Internal Medicine.
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Pure histologic patterns of Sertoli cell-only and early maturation arrest were associated with a very poor likelihood of sperm detection (4-8%). In contrast, patients with other pure pattern histologies or mixed patterns had high rates of FNA sperm detection (77-100%). Thus, sperm detection with FNA showed wide variation depending on testis histology. In addition, certain histologic patterns may reflect a more global testicular dysfunction due to underlying genetic causes, and thus a poorer likelihood of sperm identification.
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In cases of infertility due to nonobstructive azoospermia, surgical sperm retrieval for IVF-ICSI is successful 40-60% of the time without prior knowledge of the geography of testis sperm production.Tournaye H, Liu J, Nagy PZ, Camus M, Goossens A, Silber S, Van Steirtegham AC, Devroey P. Correlation between testicular histology and outcome after intracytoplasmic sperm injection using testicular spermatozoa. Hum Reprod 1996;11:127-132. With the addition of diagnostic FNA mapping, the rate of successful sperm retrieval can be increased substantially.
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The third block is hematology, which focuses on the body's blood system, including pathological diseases of blood cells. Specific focuses on histology allows students to gain a better understanding of how the microscopic structure of a tissue affects its physiologic function. The final block, Cardiology, is the first "tissue" block of the first year curriculum. Additionally, students begin anatomy lab with human cadavers as they explore the heart, lungs, mediastinum, and major bones, nerves, and muscles of the chest cavity.
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In Bolivia, all medical schools are Faculties within a University and follow the European model of a six-year curriculum (9 000 ECTS or more) divided into three cycles. The first two years are called biomedical or pre-clinical cycle. During this time students are instructed in the basic sciences (anatomy, anthropology, biochemistry, biophysics, cell biology, embryology, histology, physiology, pharmacology, biostatistics, etc.). The next three years are the clinical cycle and consist of medical specialties instruction at the faculty and hospital practice.
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Mohs surgery, developed in 1938 by a general surgeon, Frederic E. Mohs, is microscopically controlled surgery used to treat common types of skin cancer. During the surgery, after each removal of tissue and while the patient waits, the tissue is examined for cancer cells. That examination dictates the decision for additional tissue removal. Mohs surgery is the gold standard method for obtaining complete margin control during removal of a skin cancer (complete circumferential peripheral and deep margin assessment - CCPDMA) using frozen section histology.
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Rudolph Sophus Bergh Rudolph Sophus Bergh (22 September 1859 – 7 December 1924) was a Danish composer and zoologist. He was the son of physician and zoologist Rudolph Bergh. He received his general education at the Metropolitanskolen and then studied music at the Royal Danish Academy of Music and zoology at the University of Copenhagen. He later taught histology and embryology at the university and published two books in his field: Forelæsninger over den almindelige Udviklingshistorie (1887) and Forelæsninger over den dyriske Celle (1892).
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After graduating from Johns Hopkins University, Madge taught one semester at University of Pittsburgh Medical School as an instructor of gross anatomy. Then, she was briefly an assistant in physiology at Johns Hopkins University from 1919 to 1921. Later in 1921, Madge, Charles, and their two daughters moved to Canada, and Madge became a part-time instructor of histology and embryology at the University of Western Ontario. She remained in this position until 1930 when she became a part-time assistant professor.
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Brooksby attended Hyndland Secondary School in Glasgow and then the Glasgow Veterinary College. He then completed a BSc in Veterinary Science at London University while lecturing in histology at the College. In 1936 he decided on a career in animal physiology and received a grant to study for three years. He studied at three separate centres of excellence on consecutive years: University College, London; McGill University in Montreal in Canada; and the University of Edinburgh under Professor Francis Albert Eley Crew.
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In contrast, contemporary regenerative endodontic procedures consider the presence of an enriched source of stem cells within the apical tissues, their delivery into root canal systems, and the intentional release and use of local growth factors embedded into the dentin. Hence, contemporary regenerative endodontics originates from the trauma literature and embarks into the field of tissue engineering. Regeneration indicates an overall objective of reproducing the original tissue histology and function. To date, tissue engineering appears to offer the greatest opportunity for regeneration.
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In histology, an intestinal gland(also crypt of Lieberkühn and intestinal crypt) is a gland found in between villi in the intestinal epithelium lining of the small intestine and large intestine (or colon). The glands and intestinal villi are covered by epithelium, which contains multiple types of cells: enterocytes (absorbing water and electrolytes), goblet cells (secreting mucus), enteroendocrine cells (secreting hormones), cup cells, tuft cells, and at the base of the gland, Paneth cells (secreting anti-microbial peptides) and stem cells.
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There is a range of chromosomal anomalies within 45,X/46,XY where the variations are very complex, and the actual result in living individuals is often not a simple picture. Most patients with this karyotype are known to have abnormal gonadal histology and heights considerably below their genetic potential. High gonadotropin levels have been described in both male and female patients, as well as low levels of testosterone in male patients. Dosage loss of SHOX gene is commonly associated with short stature.
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Of these, the dog has the greatest number of incidents. One in four dogs older than 2 dies of cancer, a rate that has increased, which may in part be explained by reductions in other causes of death. Canine cancer shares features with human cancer, including histology, tumor genetics, molecular targets, biological behavior and therapeutic response. Canine histologies include osteosarcoma, melanoma, non-Hodgkin’s lymphoma, leukemia, prostate, breast and lung cancer, head and neck cancer, soft tissue sarcomas and bladder cancer.
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Presence of an ovarian tumour plus hormonal disturbances suggests a Leydig cell tumour, granulosa cell tumour or thecoma. However, hormonal disturbances, in Leydig tumours, is present in only 2/3 of cases. Testicular Leydig cell tumours can be detected sonographically, ultrasound examinations may be ordered in the event of a palpable scrotal lump, however incidental identification of these lesions is also possible. A conclusive diagnosis is made via histology, as part of a pathology report made during or after surgery.
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Evans became associate professor of anatomy at Johns Hopkins University. Evans moved back to California in 1915 and was made professor of anatomy at the University of California, Berkeley, and held that position until his death. His medical research at Berkeley addressed problems relating to human nutrition, endocrinology, embryology, and histology. In 1918, his research into the number of human chromosomes led him to believe the number to be 48, when most people assumed the number to be much higher.
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Lieber's current work focuses on integrating electronics in a minimally/non-invasive manner within the central nervous system. Most recently, he has demonstrated that this macroporous electronics can be injected by syringe to position devices in a chosen region of the brain. Chronic histology and multiplexed recording studies demonstrate minimal immune response and noninvasive integration of the injectable electronics with neuronal circuitry. Reduced scarring may explain the mesh electronics’ demonstrated recording stability on time scales of up to a year.
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The histology of its bones is reminiscent of terrestrial animals, not semiaquatic ones. However, support for a semiaquatic lifestyle comes from its brain anatomy, which resembles semiaquatic predators such as crocodiles more closely than terrestrial reptiles. The orientation of its ear canals suggests its neutral head posture had the snout angled upward, which would have raised the nostrils high enough for the animal to breathe while largely submerged. Proterosuchus was a predator, but the specifics of its diet are not known.
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Database of extant Ascidiacea. Version of 2 November 2007 They superficially resemble sea squirts but prey on invertebrates such as crustaceans. They also have some unique physical features that distinguish them from the ascidiaceans, including a severely reduced pharynx, the retention of the dorsal nerve cord as adults, the superficial position of their ganglion and the unique histology of the cells of their digestive tracts. The branchial syphon is large and surrounded by six large lobes; the cloacal syphon is small.
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The Helochelydridae are an extinct family of stem-turtles known from fossils found in North America and Europe that have been dated from the Late Jurassic to the Late Cretaceous. Although referred to as Solemydidae in recent literature on extinct turtles, Helochelydridae has priority over Solemydidae. They are thought to be terrestrial, based on the presence of limb osteoderms and bone histology. Their skull morphology is dissimilar to that of extant tortoises, suggesting an omnivorous habit similar to that of box turtles.
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He published his first agrostology papers on grasses in 1871 and soon became known as a world expert agrostologist on the grass family (Poaceae). While he himself undertook only a single collecting trip – to Spain and Portugal, he was charged with working up collections of grasses mainly from Japan, Taiwan, New Guinea, Brazil and Argentina. Apart from agrostologisty systematics, Hackel also contributed to the morphology and histology of members of the grass family. The genus Hackelochloa (Poaceae) is named for him.
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Evidence that there are exceptional cases came in a 2004 study on oats. The patients drafted for this study were those who had symptoms of celiac disease when on a "pure-oat" challenge, therefore not representative of a celiac sample. This study found that four patients had symptoms after oat ingestion, and three had elevated Marsh scores for histology and avenin responsive T-cells, indicating avenin-sensitive enteropathy (ASE). All three patients were the DQ2.5/DQ2 (HLA DR3-DQ2/DR7-DQ2) phenotype.
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Mallory's trichrome stain is a stain utilized in histology to aid in revealing different macromolecules that make up the cell. It uses the three stains: aniline blue, acid fuchsin, and orange G. As a result, this staining technique can reveal collagen, ordinary cytoplasm, and red blood cells. It is helpful, therefore, in examining the collagen of connective tissue. For tissues that are not directly acidic or basic, it can be difficult to use only one stain to reveal the necessary structures of interest.
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Neurothekeoma histology slide Neurothekeoma is a benign cutaneous tumor first described by Gallager and Helwig, who proposed the term in order to reflect the presumed origin of the lesion from nerve sheath. Microscopically, the lesions described closely resembled the tumor, "nerve sheath myxoma", an entity first described by Harkin and Reed. The latter had, through the years, been variously described as "Bizarre cutaneous neurofibroma", "Myxoma of nerve sheath", and "Pacinian neurofibroma". Clinically, neurothekeomas present as a solitary nodule of the skin.
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Horses have relatively poor "accommodation" (change focus, done by changing the shape of the lens, to sharply see objects near and far), as they have weak ciliary muscles.Prince JH, Diesem CD, Eglitis I, Ruskell GL. "Anatomy and histology of the eye and orbit in domestic animals." Springfield, IL: CC Thomas; 1960. However, this does not usually place them at a disadvantage, as accommodation is often used when focusing with high acuity on things up close, and horses rarely need to do so.
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Bozgan, p. 351 His scientific activity was known abroad as well as domestically, with many of his studies appearing in German. He made important advances in the histology of sensory organs in mammals and birds, publishing 34 articles on morphology, physiological anatomy and cynegetics. His discoveries pertained to the nerve endings in the tactile corpuscles of mammals, taste buds in birds, the neurofibrillary structure of nerve endings, the double innervation of striated muscle tissue and the epidermis, and glandular activity in sensory cells.
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The ages of the Aguja Formation and its primary fossil-bearing unit, the Upper Shale, are not well understood. Two radiometric dates have been taken from different sections of the upper shale, yielding ages of 72.6 Ma +/- 1.5 Ma old, and 76.9 Ma +/- 1.2 Ma old, respectively. The contact with the overlying Javelina Formation has been estimated at about 70 Ma agoWoodward, H. N. (2005). Bone histology of the sauropod dinosaur Alamosaurus sanjuanensis from the Javelina Formation, Big Bend National Park, Texas.
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Stains used: mouse monoclonal alpha-synuclein antibody; counterstained with Mayer's haematoxylin Lewy bodies Lewy bodies are abnormal aggregations of protein that develop inside nerve cells, contributing to Parkinson's disease (PD), the Lewy body dementias (Parkinson's disease dementia and dementia with Lewy bodies), and some other disorders. They are also seen in cases of multiple system atrophy, particularly the parkinsonian variant (MSA-P). They are identified under the microscope when histology is performed on the brain. Lewy bodies appear as spherical masses that displace other cell components.
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"Journal of Mammology" Brian K. McNab The armadillo can use specially evolved membranes in its nose to obtain oxygen from the surrounding soil particles without inhaling any of the soil itself."The vomeronasal organ of the South American armadillo Chaetophractus vilosus (Xenarthra, Mammalia): anatomy, histology and ultrastructure" P.D. Carmanchahi, et al. Armadillos are protected from predators by a series of thin, bony plates along the head and back. They reach sexual maturity at around 9 months and have been known to live over 30 years in captivity.
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In recent years, microscopic and other diagnostic techniques have improved dramatically. However, the tissue of origin can be still determined only about in one in four cases of CUPs with these methods. In some cases, the part of the body where cancer cells are first discovered helps the doctor decide which diagnostic tests will be most helpful. Additional clues which may be helpful in determining the primary site include the pattern of spread, and the cell type, which is based on its appearance under a microscope (histology).
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He was promoted to reader in 1965 and became dean of the Faculty of Science in 1978 until 1980. Campbell was a visiting scientist at the Field Museum of Natural History, Chicago, studying the histology of teeth in 1981. He was professor of geology from 1982 to 1993, a visiting scientist studying lungfish dentition at the School of Anatomy at Guy's Hospital, London in 1985, and following his retirement in 1992, became emeritus professor. Campbell died on 17 June 2017 at the age of 89.
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Throat cancers are classified according to their histology or cell structure, and are commonly referred to by their location in the oral cavity and neck. This is because where the cancer appears in the throat affects the prognosis - some throat cancers are more aggressive than others depending upon their location. The stage at which the cancer is diagnosed is also a critical factor in the prognosis of throat cancer. Treatment guidelines recommend routine testing for the presence of HPV for all oropharyngeal squamous cell carcinoma tumours.
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The following outline is provided as an overview of and topical guide to human anatomy: Human anatomy - scientific study of the morphology of the adult human. It is subdivided into gross anatomy and microscopic anatomy. Gross anatomy (also called topographical anatomy, regional anatomy, or anthropotomy) is the study of anatomical structures that can be seen by unaided vision. Microscopic anatomy is the study of minute anatomical structures assisted with microscopes, and includes histology (the study of the organization of tissues), and cytology (the study of cells).
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He took doctorates in medicine, biology and science. From 1974 to 2004, he was professor of histology, embryology and cytogenetics in the medical faculty of the University of Paris. Until 2004 he was also director of the laboratory of the Cochin – St Vincent de Paul – La Roche Guyon Hospital in Paris, head of the cytogenetics and pathology department, and chairman of the hospital group's advisory board. He hold tenures at the University of Alabama at Birmingham and at the Memorial Sloan-Kettering Cancer Center in New York.
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Later, his performance in his first year anatomy course earned him a second-year appointment as a student instructor in anatomy. During this time, his interest in histology developed. Under the mentorship of William Welch, Eugene Opie, and William McCallum, Whipple was inspired to correlate clinical illness and disease, to the tissue findings discovered on autopsy. Together, McCallum and Welch conspired to offer Whipple a position as junior member of the pathology department with the hope it would lead to Whipple become a pediatric pathologist.
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Small Blue Round Cell Tumor under a microscope Malignant ectomesenchymomas may form in the head and neck, abdomen, perineum, scrotum, or limbs. The tumor is defined by its heterologous rhabdomyoblastic components. MEM histology is that of an elongated cell with an embryonic morphology Holland, James F.; Frei III, Emil; Weichselbaum, Ralph R.; Bast, Robert C.; Gansler, Ted S.; Kufe, Donald W.; Pollock, Raphael E., eds. (2003), "Resemblance to embryonal tissue", Holland-Frei Cancer Medicine (6th ed.), Hamilton, Ontario, Canada: BC Decker, , OCLC 53895425, retrieved 3 Dec 2011.
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During his tenure at Michigan, he often held out-dated theories of disease causation despite considerable advances in bacteriology. He claimed that phthisis and tuberculosis were separate diseases and that the tubercle bacillus was not proven as the cause of either. In 1895 he moved to Detroit in 1898 to become the city's Health Officer and Professor of Internal Medicine and Pathology at the Michigan College of Medicine and Surgery. He wrote two books, Practical Histology (1880) and Practical pathology and morbid anatomy (1891).
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Jean Binot (11 August 1867 – 25 November 1909) was a French microbiologist born in Saint-Mandé, Val-de-Marne. He studied medicine in Paris, where one of his instructors was Raphael Blanchard (1857-1919). In 1887 he began work as an assistant préparateur in histology at the Collège de France, followed by an assignment as externe to the hospitals of Paris. In 1892 he became a hospital interne, and during the following year began taking courses in microbiology at the Pasteur Institute in Paris.
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For example, maggots were believed to appear spontaneously in decaying meat; Francesco Redi carried out experiments that disproved this notion and coined the maxim Omne vivum ex ovo ("Every living thing comes from a living thing" — literally "from an egg"); Virchow (and his predecessors) extended this to state that the only source for a living cell was another living cell.Virchow, R. (1858). Cellular pathology: As based upon physiological and pathological histology, 20 lectures delivered in the Pathological Institute of Berlin, during Feb. Mar. and Apr. 1858.
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In 1959 Yves Rumpler was appointed assistant chief in the Institute of Embryology at the University of Strasbourg and until 1966 his research focused on traditional subjects studied at Strasbourg e.g. thyroid hormones, teratology. From 1966 to 1976, Yves Rumpler was an associate lecturer in histology and embryology at the National School of Medicine, Tananarive, Madagascar (now part of the University of Antananarivo). He undertook studies on the systematic and chromosomal evolution of the lemurs in Madagascar and is consequently recognized for his work in primatology.
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With his associate Johann Veit (1852–1917), he is credited with establishing the groundwork for contemporary gynecological pathology and histology. In the 1870s the two men introduced the surgical biopsy as a necessary diagnostics tool. From their biopsies, they demonstrated that there were too many cases of unnecessary surgeries for cervical cancer, proving that physicians were often incapable of detecting cancer without the aid of a biopsy. Ruge is also credited with having first defined varicose veins as "any dilated, elongated and tortuous vein irrespective of size".
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Luis Simarro Lacabra (6 January 1851 - 19 June 1921) was a Spanish psychiatrist who was born in Rome while his parents were living in Italy. He studied medicine in Valencia and Madrid, and in 1877 was appointed director of the Santa Isabel insane asylum at Leganés, outside of Madrid. From 1880 he lived in Paris and studied general anatomy and histology with Louis-Antoine Ranvier and clinical neurology under Jean Martin Charcot. Here he also came under the influence of philosopher Ernest Renan (1823–1892).
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A small bone fragment from the European Paleocene has been considered the only plausible post-Cretaceous record, but this identification is based on comparative bone histology methods of doubtful reliability. The fossil record is unique because coelacanth fossils were found 100 years before the first live specimen was identified. In 1938, Courtenay- Latimer rediscovered the first live specimen, L. chalumnae, caught off the coast of East London, South Africa. In 1997, a marine biologist on honeymoon discovered the second live species, Latimeria menadoensis, in an Indonesian market.
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Krüger studied veterinary medicine at the Ludwig Maximilian University of Munich (LMU). After completing her studies in 1996, she accepted a position as scientific assistant at the Institute for Animal Anatomy and Histology at the LMU in Munich. From April 1999 to February 2006, she ran the Einthal Equestrian Park in Obertraubling, together with her husband. From June 2004, she held a research position at Biology 1 in the department of Zoology at the University of Regensburg, researching social learning and social cognition in horses.
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Added difficulties for diagnosis are the fact that serological markers (anti-tissue transglutaminase [TG2]) are not always present and many people may have minor mucosal lesions, without atrophy of the intestinal villi. Diagnosis of CD should be based on a combination of person’s familial history, genetics (i.e. presence of HLA DQ2/DQ8) serology and intestinal histology. CD affects approximately 1–2% of general population all over the world, but most cases remain unrecognized, undiagnosed and untreated, and exposed to the risk of long-term complications.
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The usage of illustrations in histology, deemed as useless by Bichat, was promoted by Jean Cruveilhier. In the early 1830s Purkynĕ invented a microtome with high precision. During the 19th century many fixation techniques were developed by Adolph Hannover (solutions of chromates and chromic acid), Franz Schulze and Max Schultze (osmic acid), Alexander Butlerov (formaldehyde) and Benedikt Stilling (freezing). Mounting techniques were developed by Rudolf Heidenhain (gum Arabic), Salomon Stricker (mixture of wax and oil), Andrew Pritchard (gum and isinglass) and Edwin Klebs (Canada balsam).
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Dercum was born in Philadelphia, Pennsylvania. He was educated at the local high school and attended medical school of the University of Pennsylvania. He received his medical degree in 1877. He began his medical practice and served as a consultant pathologist at the State Mental Hospital in Norristown, Pennsylvania. In 1879, at the University of Pennsylvania, he was a demonstrator in histology. In 1881, he was demonstrator in the physiology laboratory, and in 1882, he was an instructor in nervous diseases, also at the University of Pennsylvania.
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Clearing methods, including 3DISCO, was mainly developed for neuroscience research first. The reason is in high morphological and functional complexity of nervous system, which investigation is time-consuming and laborious with classical histology methods. Majority of studies is therefore focused on mouse central nervous system (rodents are one of main model organisms for neurobiology). Authors of 3DISCO method used it first for studying regeneration in the central nervous system (CNS) of mouse, including counting of microglia, astrocytes and mapping trajectories of axons after injury.
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Stricker was born in Waag-Neustadtl (Hungarian: Vágújhely, now Nové Mesto nad Váhom in Slovakia). He studied at the University of Vienna, and subsequently became a research assistant at the Institute of Physiology under Ernst Wilhelm von Brücke. Later he became head of the Institute of General and Experimental Pathology in Vienna. Stricker is remembered for his extensive studies in the fields of histology and experimental pathology, and is credited with making discoveries involving the diapedesis of erythrocytes and the contractility of vascular walls.
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Many spinosaurs likely had semiaquatic habits, as has been shown in studies using techniques like isotope analysis and bone histology. It has been found that they probably took advantage of aquatic prey and environments (usually marginal and coastal habitats) to occupy a distinct ecological niche, therefore avoiding competition with more terrestrial theropods. Spinosaurines appear to have been more adapted for such lifestyles than baryonychines. A 2018 study by British paleontologist Thomas M. S. Arden and colleagues examined the morphology of spinosaurine skull bones for possible aquatic traits.
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Birbeck granules Birbeck granules, also known as Birbeck bodies, are rod shaped or "tennis-racket" cytoplasmic organelles with a central linear density and a striated appearance. First described in 1961 (where they were simply termed "characteristic granules"), they are solely found in Langerhans cells. Although part of normal Langerhans cell histology, they also provide a mechanism to differentiate Langerhans cell histiocytoses (which are a group of rare conditions collectively known as histiocytoses) from proliferative disorders caused by other cell lines. Formation is induced by langerin.
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Merocrine secretion Merocrine (or eccrine) is a term used to classify exocrine glands and their secretions in the study of histology. A cell is classified as merocrine if the secretions of that cell are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and then onto a bodily surface or into the lumen. Merocrine is the most common manner of secretion. The gland releases its product and no part of the gland is lost or damaged (compare holocrine and apocrine).
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The generic name refers to Sierrita de la Cruz Creek where the holotype was found, and the specific name refers to Archie MacAlpin, who discovered the skeleton. Based on the histology of the scutes of the holotype, the individual was a subadult that was not fully grown. Sierritasuchus can be distinguished from other aetosaurs by several unique features as well as a distinct combination of features in its scutes. Unlike other aetosaurs, Sierritasuchus has recurved spines along its side that are serrated on the front edges.
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Pemphigus is an autoimmune disease caused by antibodies directed against both desmoglein 1 and desmoglein 3 present in desmosomes. Loss of desmosomes results in loss of cohesion between keratinocytes in the epidermis, and a disruption of the barrier function served by intact skin. The process is classified as a type II hypersensitivity reaction (in which antibodies bind to antigens on the body's own tissues). On histology, the basal keratinocytes are usually still attached to the basement membrane leading to a characteristic appearance called "tombstoning".
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Some early workers who did not know the structure. called it phospho-24-tungstic acid, formulating it as 3H2O·P2O5 24WO3·59H2O, (P2W24O80H6)·29H2O, which correctly identifies the atomic ratios of P, W and O. This formula was still quoted in papers as late as 1970. Phosphotungstic acid is used in histology as a component for staining of cell specimens, often together with haematoxylin as PTAH. It binds to fibrin, collagen, and fibres of connective tissues, and replaces the anions of dyes from these materials, selectively decoloring them.
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Wacław Mayzel was born on September 12, 1847 to Józef and Rozalia (Minheymer) Mayzel, in Kunów, Poland. Having graduated St Ann's secondary school in Cracow in 1865, he enrolled at the Faculty of Medicine in the Warsaw General School. Five years later, Mayzel earned a doctorate in the field. During his time as a student, and while working at Henryk Fryderyk Hoyer's (senior) Institute of Histology and Physiology, he wrote a paper titled Poszukiwania nad powstawaniem ropy (Exploring the formation of pus), critically acclaimed by his faculty.
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Buiuc, p.166 In 1892, he left for the University of Paris, and would remain in the French capital for a decade. At the medical faculty there, his professors included Louis Hubert Farabeuf (anatomy), Mathias-Marie Duval (histology), Paul Georges Dieulafoy, Pierre Potain and Sigismond Jaccoud (internal pathology), Paul Jules Tillaux and Paul Reclus (surgery) and Jean- Martin Charcot (neurology). He also attended Édouard Brissaud's optional course on the history of medicine. In 1894, he began working as an extern in the Paris hospitals.
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Miloš Marić (; ; 20 April 1885, in Ruma, Austria-Hungary, now Serbia – 3 May 1944, in Saratov, Soviet Union, now Russia) was a Russian scientist of Serbian origin, head of the department of histology at the Saratov State University. He entered the history of medicine with his most important research in the field of mitosis and amitosis, which laid the foundation for cloning. His older sister was Mileva Marić, the first wife of Albert Einstein who was also a scientist (physicist) in her own right.
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She studied broadly, in Latin, English literature, history, and the sciences, becoming the first woman in the university's history to take a laboratory physics class. While still an undergraduate, she became fascinated with zoology and especially anatomy, taking every class offered in these subjects. She went on to earn her Ph.D. at Cornell in 1880. In 1881, Phelps married Simon Henry Gage (1851–1944), who was already an assistant professor of histology and embryology at Cornell, where he would spend his entire academic career.
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H.G. Burkitt et al., Wheater's Functional Histology, 3rd ed. The etymology suggests this, since the Latin names translate to "the mucosa's own special layer" (lamina propria mucosae) and "muscular layer of the mucosa" (lamina muscularis mucosae). The muscularis mucosae is composed of several thin layers of smooth muscle fibers oriented in different ways which keep the mucosal surface and underlying glands in a constant state of gentle agitation to expel contents of glandular crypts and enhance contact between epithelium and the contents of the lumen.
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Histology of articular cartilage zones. -"The work is made available under the Creative Commons CC0 public domain dedication." Articular cartilage is hyaline cartilage on the articular surfaces of bones, and lies inside the joint cavity of synovial joints, bathed in synovial fluid produced by the synovial membrane, which lines the walls of the cavity. Though it is often found in close contact with menisci and articular disks, articular cartilage is not considered a part of either of these structures, which are made entirely of fibrocartilage.
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Micrograph demonstrating amyloid deposition (red-orange) with Congo red staining in cardiac amyloidosis. In histology and microscopy, Congo red is used for staining in amyloidosis, and for the cell walls of plants and fungi, and for the outer membrane of Gram- negative bacteria. Apple-green birefringence of Congo red stained preparations under polarized light is indicative of the presence of amyloid fibrils. Additionally, Congo red is used for the diagnostics of the Shigella flexneri serotype 2a, where the dye binds the bacterium's unique lipopolysaccharide structure.
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A micrograph showing cells with marked nuclear shape and size variation, a component of nuclear pleomorphism. Pleomorphism is a term used in histology and cytopathology to describe variability in the size, shape and staining of cells and/or their nuclei. Several key determinants of cell and nuclear size, like ploidy and the regulation of cellular metabolism, are commonly disrupted in tumors. Therefore, cellular and nuclear pleomorphism is one of the earliest hallmarks of cancer progression and a feature characteristic of malignant neoplasms and dysplasia.
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In 2006, the U.S. Food and Drug Administration (FDA) approved bevacizumab for use in first-line advanced nonsquamous non-small cell lung cancer in combination with carboplatin/paclitaxel chemotherapy. The approval was based on the pivotal study E4599 (conducted by the Eastern Cooperative Oncology Group), which demonstrated a two-month improvement in overall survival in patients treated with bevacizumab (Sandler, et al. NEJM 2004). A preplanned analysis of histology in E4599 demonstrated a four-month median survival benefit with bevacizumab for people with adenocarcinoma (Sandler, et al.
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Eusebio Oehl (December 5, 1827 – April 10, 1903) was an Italian histologist and physiologist who was a native of Lodi. He studied medicine at the University of Pavia, and following graduation (1850), he continued his education in Vienna under Joseph Hyrtl (1810-1894) and Ernst Wilhelm von Brücke (1819-1892). Afterwards, he returned to Pavia, where he taught classes in histology at the Collegio Ghislieri and at the university. In 1864 he attained the chair of physiology at the institute of physiology in Pavia.
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Gerbertus is a journal devoted to the history of science in the middle ages. In 1971, the specimens were analyzed by Odoardo Linoli, a professor in anatomy and pathological histology as well as chemistry and clinical microscopy, and former head of the Laboratory of Pathological Anatomy at the Hospital of Arezzo. He published his results in Quaderni Sclavo di Diagnostica Clinica e di Laboratori in 1971. Linoli's analysis was confirmed in 1981 by Ruggero Bertelli, a retired professor of human anatomy at the University of Siena.
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McGraw-Hill, New YorkMallory FB (1983) Pathological techniques: A practical manual for workers in pathological histology including directions for the performance of autopsies and for microphotography. In: Mallory NY (eds) WB Saunders, Philadelphia, PA, pp 143–144 It is a precipitation reaction in which silver ions react with phosphate in the presence of acidic material. Photo chemical degradation of silver phosphate to silver happens under light illumination. Additional methods need to be employed to confirm the presence of calcium, such as Alizarin Red S.
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Since testicular cancers can spread, patients are usually offered adjuvant treatment - in the form of chemotherapy or radiotherapy - to kill any cancerous cells that may exist outside of the affected testicle. The type of adjuvant therapy depends largely on the histology of the tumor (i.e. the size and shape of its cells under the microscope) and the stage of progression at the time of surgery (i.e. how far cells have 'escaped' from the testicle, invaded the surrounding tissue, or spread to the rest of the body).
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Immune-system cells, neutrophils and plasma cells, accumulate in the skin, in densities that may cause microabscesses. Warthin-Starry or Levaditi silver stains selectively stain T. pallidum, and direct and indirect immunofluorescence and immunoperoxidase tests can detect polyclonal antibodies to T. pallidums. Histology often shows some spatial features which distinguish yaws from syphilis (syphilis is more likely to be found in the dermis, not the epidermis, and shows more endothelial cell proliferation and vascular obliteration). Blood-serum (serological) tests are increasingly done at the point of care.
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Mesothelioma often has a poor prognosis. Typical survival despite surgery is between 12 and 21 months depending on the stage of disease at diagnosis with about 7.5% of people surviving for 5 years. Women, young people, people with low-stage cancers, and people with epithelioid cancers have better prognoses. Negative prognostic factors include sarcomatoid or biphasic histology, high platelet counts (above 400,000), age over 50 years, white blood cell counts above 15.5, low glucose levels in the pleural fluid, low albumin levels, and high fibrinogen levels.
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In anatomy and histology, the term wandering cell (or ameboid cell)ameboid+cell at eMedicine Dictionary is used to describe cells that are found in connective tissue, but are not fixed in place. This term is used occasionally and usually refers to blood leukocytes (which are not fixed and organized in solid tissue) in particular mononuclear phagocytes. Frequently, the term refers to circulating macrophages and has been used also for stationary macrophages fixed in tissues (histiocytes), which are sometimes referred to as "resting wandering cells".
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A 2017 study examined the histology of thin-sectioned dodo bones, modern Mauritian birds, local ecology, and contemporary accounts, to recover information about the life history of the dodo. The study suggested that dodos bred around August, after having potentially fattened themselves, corresponding with the fat and thin cycles of many vertebrates of Mauritius. The chicks grew rapidly, reaching robust, almost adult, sizes, and sexual maturity before Austral summer or the cyclone season. Adult dodos which had just bred moulted after Austral summer, around March.
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Unlike those in bone, however, these canals in cementum do not contain nerves, nor do they radiate outward. Instead, the canals are oriented toward the periodontal ligament (PDL) and contain cementocytic processes that exist to diffuse nutrients from the ligament because it is vascularized.Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 171 The progenitor cells also found in the PDL region contribute to the mineralization of the tissue. Once in this situation, the cementoblasts lose their secretory activity and become cementocytes.
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Identification of 45,X/46,XY karyotype has significant clinical implications due to known effects on growth, hormonal balance, gonadal development and histology. 45,X/46,XY is diagnosed by examining the chromosomes in a blood sample. The age of diagnosis varies depending on manifestations of disease prompting reason for cytogenetic testing. Many patients are diagnosed prenatally due to fetal factors (increased nuchal fold, or abnormal levels of serum), maternal age or abnormal ultrasounds, while others will be diagnosed postnatal due to external genital malformation.
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Cerebrospinal fluid specimen stained with Perls Prussian blue showing iron containing macrophage (stained blue) surrounded by erythrocytes (stained red). Perls Prussian blue is a commonly used method in histology, histopathology, and clinical pathology to detect the presence of iron in tissue or cell samples. Perls Prussian Blue derives its name from the German pathologist Max Perls (1843–1881), who described the technique in 1867. The method does not involve the application of a dye, but rather causes the pigment Prussian blue to form directly within the tissue.
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Deciduous teeth – commonly known as baby teeth, milk teeth, temporary teeth,Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 255 and primary teeth – are the first set of teeth in the growth development of humans and other diphyodont mammals. They develop during the embryonic stage of development and erupt (that is, they become visible in the mouth) during infancy. They are usually lost and replaced by permanent teeth, but in the absence of permanent replacements, they can remain functional for many years.
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Višinskis attended lectures of botany by Andrey Beketov, anatomy by Peter Lesgaft, histology by Alexander Dogiel, organic chemistry by Nikolai Menshutkin, geology by Vasily Dokuchaev, and other famous professors. He struggled with chemistry and physics, the latter he failed and was required to repeat the first year. He also attended meetings of the Russian Anthropological Society and the Imperial Russian Geographical Society. He continued to participate in Lithuanian cultural life, writing his first fiction Paparčių žiedai (Fern Flowers) during the Christmas break in 1894.
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Most, and perhaps all, cases of synovial sarcoma are associated with a reciprocal translocation t(x;18)(p11.2;q11.2). There is some debate about whether the molecular observation itself is definitive of synovial sarcoma. The diagnosis of synovial sarcoma is typically made based on histology and is confirmed by the presence of t(X;18). This translocation event between the SS18 gene on chromosome 18 and one of 3 SSX genes (SSX1, SSX2 and SSX4) on chromosome X causes the presence of an SS18-SSX fusion gene.
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Uvarov studied at the University of London Royal Veterinary College, where she won the college's bronze medals for Physiology and Histology and qualified in 1934. Following graduation, Uvarov worked first in general mixed practice as an assistant veterinary surgeon, before establishing her own practice in 1944 in Surrey. In 1953, Uvarov joined the Veterinary Department of Glaxo Laboratories Ltd, where she was involved in product development and training sales representatives. While at Glaxo, Uvarov published her research on the development of antimicrobials, and their use in animals.
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Indium oxide is used in some types of batteries, thin film infrared reflectors transparent for visible light (hot mirrors), some optical coatings, and some antistatic coatings. In combination with tin dioxide, indium oxide forms indium tin oxide (also called tin doped indium oxide or ITO), a material used for transparent conductive coatings. In semiconductors, indium oxide can be used as an n-type semiconductor used as a resistive element in integrated circuits. In histology, indium oxide is used as a part of some stain formulations.
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Urine diastase is useful in diagnosing uncertain abdominal cases (especially when pancreatitis is suspected), stones in the common bile duct (choledocholithiasis), jaundice and in ruling out post-operative injury to the pancreas; provided that the diastase level is correlated with clinical features of the patient. Diastase is also used in conjunction with periodic acid–Schiff stain in histology. For example, glycogen is darkly stained by PAS but can be dissolved by diastase. Fungi, on the other hand, stains darkly with PAS even after treatment by diastase.
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Marcello Malpighi (10 March 1628 – 29 November 1694) was an Italian biologist and physician, who is referred to as the "Founder of microscopical anatomy, histology & Father of physiology and embryology". Malpighi's name is borne by several physiological features related to the biological excretory system, such as the Malpighian corpuscles and Malpighian pyramids of the kidneys and the Malpighian tubule system of insects. The splenic lymphoid nodules are often called the "Malpighian bodies of the spleen" or Malpighian corpuscles. The botanical family Malpighiaceae is also named after him.
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The taxon was reassigned to the newly named genus Plagiosuchus in 1922 by von Huene, who described new material that permitted him to differentiate it from Plagiosternum granulosum; this was also when the specific epithet was grammatically modified. Additional material was referenced and briefly figured by Hellrung (2003) and Werneburg and Witter (2005), but most of the osteology comes from the description of a complete skull, figured by Hellrung, by Damiani et al. (2009). Histology of the osteoderms and the limbs has also been analyzed.
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The legs, like many from the order Artiodactyla, had four fingers of which only two were used to walk. The tail was rather long in comparison to the rest of the body. The bone histology of Myotragus shows lamellar-zonal tissue throughout the cortex, a feature otherwise typical of ectothermic reptiles. The growth of bones in Myotragus is unlike any other mammal and similar to crocodilians in showing slow and adaptive rates, intermittently ceasing growth altogether, and reaching somatic maturity by about 12 years.
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Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 135 The buccinator acts as a valve that prevents air forcing into the duct, which would cause pneumoparotitis. Running along with the duct superiorly is the transverse facial artery and upper buccal nerve; running along with the duct inferiorly is the lower buccal nerve. The exit of the parotid ducts can be felt as small bumps (Papillae) on both sides of the mouth, and are usually positioned next to the maxillary second molars.
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It is also unknown how tumor histology affects ctDNA release. Another major limitation with using only ctDNA levels to detect tumor burden is that ctDNA can only predict residual tumor, it can tell nothing about the location of the tumor. This means that CAPP-Seq can be best used in complementary with other sequencing approaches for imaging disease burden at different times. Thus, technical sensitivity, reproducibility, specificity and requirement of expertise for analysis of large amount of data are some of the concerned issues with the technique.
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Lolaniso Ibrohimovna Ismoilova () (born October 4, 1929) is a Tajikistani biologist, active during the Soviet era. Born into a working-class family in Dushanbe, Ismoilova graduated from the Department of Biology of the Tajikistan State University in 1953. In 1965 she joined the Communist Party of the Soviet Union. She became an assistant professor in the Department of Histology at the University in 1970, and in 1974 was promoted to become head of the Department of Biology and General Genetics of the Tajikistan State Medical Institute.
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Subsequently it is cut frozen with the microtome portion of the cryostat, the section is picked up on a glass slide and stained (usually with hematoxylin and eosin, the H&E; stain). The preparation of the sample is much more rapid than with traditional histology technique (around 10 minutes vs 16 hours). However, the technical quality of the sections is much lower. The entire laboratory can occupy a space less than , and minimal ventilation is required compared to a standard wax embedded specimen laboratory.
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Histology of Medulloepithelioma The World Health Organization has classified the central nervous system primitive neuroectodermal tumors into five subtypes: neuroblastoma, ganglioneuroblastoma, medulloepithelioma, ependymoblastoma, and not otherwise specified PNET. The last one encompasses the PNETs with varying characteristics that hasn't been well defined yet. Neuroblastomas are PNETS that involve the process of cell differentiation into neurons, while ganglioneuroblastomas are PNETs that involve ganglion cells. Medulloepithelioma, on the other hand, are tumors involving the constant cell division on the epithelium tissue where bundle of neuron endings are located.
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A microtome (from the Greek mikros, meaning "small", and temnein, meaning "to cut") is a tool used to cut extremely thin slices of material, known as sections. Important in science, microtomes are used in microscopy, allowing for the preparation of samples for observation under transmitted light or electron radiation. Microtomes use steel, glass, or diamond blades depending upon the specimen being sliced and the desired thickness of the sections being cut. Steel blades are used to prepare sections of animal or plant tissues for light microscopy histology.
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While she was a graduate student at Cornell University, she was an assistant in the Histology and Embryology Department, teaching and researching under professor Simon Henry Gage; Gage's expertise in microscopy shaped Read's later work.Cornell University, The Register (1906): 301-302. Read's work at the U. S. Department of Agriculture's Bureau of Chemistry (the precursor to the U. S. Food and Drug Administration) focused on the detection of adulterated foods,"Government Women Who Hold Unique or Lucrative Jobs" Miami News (November 29, 1913): 7. via Newspapers.
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Carl Wedl (October 14, 1815 - September 21, 1891) was an Austrian pathologist who was a native of Vienna. In 1841 he obtained his doctorate in Vienna, and subsequently practiced medicine in Ischl and Salzburg. In 1844 he took a scientific journey to France and England, afterwards returning to Vienna, where he performed histological research. With assistance from Karl Rokitansky (1804-1878), he received his habilitation in 1849. In 1853 he became an associate professor, and in 1872 was appointed professor of histology at the University of Vienna.
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After finishing his primary education in Kairouan, Ain drahem and Kelibia, Mongi Ben Hamida completed his secondary education at Sadiki College, where he got his baccalaureate degree in 1948. Later, he enrolled in medical studies at the Medical School of Paris (divided in 1970) where he specialized in neurology. His thesis on the dento-olivary pair in 1965 won him a Prix de Thèse (thesis prize) and quickly became an international clinical and neuropathological reference. Mongi Ben Hamida held a diploma of advanced studies in histology and cytology under the direction of Professor René Couteaux.
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At the age of 75, Holliday developed Non-Hodgkin lymphoma, a type of blood cancer. He spent the rest of his life in retirement; growing vegetables, reading a large number of books (including Gibbon's lengthy The History of the Decline and Fall of the Roman Empire), and rediscovering his interest in histology (including analysing samples of his own blood). He had developed cancer twice in his last few years. Holliday died on 5 September 2016, a few weeks short of his 81st birthday, at the Aberdeen Royal Infirmary.
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This may indicate that certain genetic features drives cellular changes which ultimately effect fluid movement which can be seen on MRI and these features are predominantly associated with poor prognosis. The combination of more dangerous genetic alterations, histology and clinical outcomes for patients with prostate tumours which are visible on mpMRI, has lead to suggestions that the definition of 'clinically significant cancer' should be at least in part based on mpMRI findings. The radiogenomic approach has been also successfully applied in breast cancer. In 2014, Mazurowski et al.
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MLS in his work environment Medical laboratory scientists work in all areas of the clinical laboratory, including blood banking, chemistry, hematology, immunology, histology and microbiology . They perform a full range of laboratory tests – from simple prenatal blood tests to more complex tests to uncover diseases such as HIV/AIDS, diabetes, and cancer. They are also responsible for confirming the accuracy of test results, and reporting laboratory findings to pathologists and other physicians. The information that a medical laboratory scientist gives to the doctor influences the medical treatment a patient will receive.
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CUBIC (abbreviation for “clear, unobstructed brain imaging cocktails and computational analysis) is a histology method that allows tissues to be transparent (process called “tissue clearing”). As a result it makes investigation of large biological samples with microscopy easier and faster. The method was published in 2014 by Etsuo A. Susaki and Hiroki R. Ueda, primarily for use in neurobiology research of brains from model organisms like rodents or small primates. But in upcoming years there were other works published, using CUBIC method on other tissues like lymph nodes or mammary glands.
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Various approaches have been developed and employed for the diagnosis of BFDV. These include histology, electron microscopy, haemagglutination, immunohistochemistry, in situ hybridisation, polymerase chain reaction (PCR), duplex shuttle PCR, real-time PCR, PCR followed by high- resolution melting curve analysis, and swarm primer-applied loop-mediated isothermal amplification (sLAMP). The serological detection of anti-BFDV antibodies has been conducted by haemagglutination inhibition and Enzyme- Linked Immunosorbent Assay (ELISA). So far, the standard PCR-based assay has been used most frequently (>49%) to screen BFDV between 1984 and July 2015.
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38 No. (Supplement 1) 2010Nurcan Özyurt, Selami Candan & Zekiye Suludere: The morphology and histology of the male reproductive system in Apodiphus amygdali (Germar, 1817) (Hemiptera: Heteroptera: Pentatomidae) Life: The Excitement of Biology 2(1) They have two generations a year, the first at the end of June and the second at mid-August. Adults of this second generation over winter from October to May. The fertilized females lay on the underside of the leaves masses of eleven to fifteen eggs, which take two to five days to hatch. Nymphs pass through five moltings.
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The habitat of Timimus consisted of polar forests with mild summers but cold and dark winters due to the closer proximity of the area to the South Pole during the Early Cretaceous. In 1996, Anusuya Chinsamy, an expert on the microstructure of fossil bones, examined bone material from Timimus and Leaellynasaura and discovered they exhibited different bone histology. The ornithischian showed a continuous rate of bone deposition, while the coelurosaur had a cyclical pattern of bone formation, which suggested Timimus may have hibernated in colder months.Chinsamy, A., Rich, T., and Rich-Vickers, P. (1996).
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As with Stegoceras, the wide age range present in specimens of Foraminacephale allows for analysis of the ontogeny, or growth, of the dome. Measurements of 27 different points on 21 Foraminacephale skulls showed that the dome became proportionally taller with age, but did not become significantly wider. Histology of the specimens showed that the domes became less porous with age - the smallest specimen's skull was 1.67% empty space, while the largest specimen's skull was 0.25% empty space. Generally, the frontal part of the dome was more porous than the parietal part.
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The monument of Tarkhanov in front of Tbilisi Medical University Tarkhanov worked intensively at translating many medical and physiology textbooks, among them Technical Textbook of Histology, by L.-A. Ranvier (1876) and General Muscle and Nerve Physiology by I. Rosenthal (1879). Between the years 1892 and 1904, Tarkhanov contributed nearly 160 articles, from B to Z, in physiology and medicine to the Brockhaus and Efron Encyclopedic Dictionary. Following his resignation from the St. Petersburg Military Medical Academy, he published during the period 1897–1908 nearly 250 popular articles on a variety of topics.
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The basic sciences run through the first 5 semesters. This covers all subjects related to anatomy and neuroanatomy; histology; embryology; basic genetics; biochemistry and molecular biology; physiology and neurophysiology; human conduct and psychopathology; gross and histologic pathology; microbiology and parasitology; biostatistics; basic clinical (theoretical) psychiatry; pharmacology; pathophysiology; semiology and family medicine. This bloc also covers several ethics subjects including medicine and human values, as well as health anthropology. Throughout, students must practise on the corpses available at the amphitheatre; microscopic and lab analyses, as well as physiology lab analyses.
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Kazan State Medical University (KSMU) is located in the central part of Kazan. The KSMU main campus is on Butlerov Street, although there are also other KSMU buildings throughout Kazan. The main campus includes main libraries, the museum, the departments of foreign languages, history, philosophy, political science and sociology, medical biology and genetics, public health and organization of healthcare, economical theory and social work, general and organic chemistry, microbiology, pathological physiology. A further set of buildings based around Universitetskaya Street includes the departments of physiology, histology and anatomy.
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At the age of fourteen, he rebelled against his father's plan to train for the clergy, and he left home to sail to the East Indies and returned only at the age of twenty one. He then studied under private tutors and went to the University of Aberdeen. He became a licentiate of the Royal College of Physicians in 1879 and in 1887 he became Professor of Physiology and Normal and Morbid Histology at Westminster Hospital Medical School. He was a curator of the anatomical museum at King's College.
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Portrait from Saint Bartholomew's Hospital archives Emanuel Edward Klein FRS (31 October 1844 at Osijek – 9 February 1925 at Hove) was a bacteriologist who was born in Croatia and educated in Austria before settling in Britain. He is sometimes known as the father of British microbiology, but most of his work in microbiology, histology, and bacteriology was overshadowed during his life by his use of and apparently outspoken support for animal vivisection in physiological and medical experiments. His English was poor and during court questioning, many of the answers he provided were considered shocking.
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400px The school's campus is located on Little Hill () and consists of four separate buildings. The historical M. R. Štefánik building is home to the three National Centres of Excellence, the school's nursing academy, and is also used for the teaching of Latin for first year medical students. The main building headquarters many of the pre-clinical medical departments, such as anatomy, histology, embryology, biophysics and medical biology. The assembly hall houses the dean's office and the aula magna, which itself is used for conferences, graduations, inaugurations, matriculation, and other events.
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The MZUSP has one of the largest natural-history collections in Latin America, with over 8.5 million preserved specimens of vertebrates (amphibians, mammals, birds, fish and reptiles) and invertebrates (cnidarians, insects, crustaceans, arachnids, myriapods, annelids, mollusks and other marine groups). Each collection is curated independently, and organized according to specific needs. Other facilities in the museum include a library specializing in zoology and laboratories dedicated to research in chronobiology, electron microscopy, molecular biology, histology and CT scans. MZUSP also operates the Boracéia Biological Station in the forest near Salesópolis for field research.
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Left to right: denticles of Paralogania (?), Shielia taiti, Lanarkia horrida The bony scales of thelodonts, the most abundant form of fossil fish, are well understood. The scales were formed and shed throughout the organisms' lifetimes, and quickly separated after their death. Bone, a tissue that is both resistant to mechanical damage and relatively prone to fossilization, often preserves internal detail, which allows the histology and growth of the scales to be studied in detail. The scales comprise a non-growing "crown" composed of dentine, with a sometimes-ornamented enameloid upper surface and an aspidine base.
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Hope Hibbard (December 18, 1893- May 12, 1988) was an American biologist, cytologist, zoologist, and professor of zoology. Born in Altoona, Pennsylvania, she conducted research in the fields of histology and marine biology, utilizing organisms such as silkworms, limpets, earthworms, and frogs. Hibbard dedicated most of her life to education as a professor at multiple institutions, including Bryn Mawr College, Elmira College, and Oberlin College. She received accolades for her research and academic merits, such as the Sarah Berliner Fellowship and the Adelia A. Field Johnston Professor of Zoology.
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Defining cerebral cytoarchitecture began with the advent of histology—the science of slicing and staining brain slices for examination. It is credited to the Viennese psychiatrist Theodor Meynert (1833–1892), who in 1867 noticed regional variations in the histological structure of different parts of the gray matter in the cerebral hemispheres.Meynert, T. (1872) Der Bau der Gross- Hirnrinde und seine örtlichen Verschiedenheiten, nebst einem pathologisch–anatomischen Corollarium. J.H. Heuser’sche Verlagsbuchhandlung, Neuwied & Leipzig. Paul Flechsig was the first to present the cytoarchitecture of the human brain into 40 areas.
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This a six-year program divided within three cycles. First cycle: Theory and lectures (1-2), second cycle: pre-clinical training (3-4) and third cycle: clinical training (5-6). First year consists mainly of theoretical classes, however there are practice since first day in laboratories and institutes, such as biochemistry, anatomy which included lectures and teaching sessions with cadavers in dissection tables, Molecular Biology, histology, embryology and many others general subjects. The second year is usually mainly quite theoretical although most teaching sessions takes place in laboratories.
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Along with her sister, Edith earned a Bachelor of Philosophy from Buchtel in 1892. She then went on to Cornell University, and wrote her Master of Science thesis on white blood cells in 1893. From 1894 to 1899, Claypole served as a professor of physiology and histology at Wellesley College, and also headed the zoology department for two years. In 1899, she started work in the medical department at Cornell where she stayed until 1901 when she moved to Pasadena to be near her stepmother, who was ill.
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The ICD-10 lists macroglossia under "other congenital malformations of the digestive system". Definitions of macroglossia have been proposed, including "a tongue that protrudes beyond the teeth during [the] resting posture" and "if there is an impression of a tooth on the lingual border when the patients slightly open their mouths". Others have suggested there is no objective definition of what constitutes macroglossia. Some propose a distinction between true macroglossia, when histologic abnormalities correlate with the clinical findings of tongue enlargement, and relative macroglossia, where histology does not provide a pathologic explanation for the enlargement.
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Later in his life, he became involved in researching how altitude changes in the Andes affected anatomy and histology in human beings, men specifically. It had long been thought that the multiple cases of pulmonary hypertension in Andes men came from the altitude they lived in. Arias Stella's research showed that "hypoxia-induced thickening of the pulmonary arteriolar walls" was the main cause for the hypertension. Considering that the natives had no access to vasodilators, their cases of hypertension were found to be different from known cases of acute hypoxic pulmonary vasoconstriction.
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Charles-Philippe Robin Charles-Philippe Robin (4 June 1821 – 6 October 1885) was a French anatomist, biologist, and histologist born in Jasseron, département Ain. He studied medicine in Paris, and while still a student took a scientific journey with Hermann Lebert to Normandy and the Channel Islands, where they collected specimens for the Musée Orfila. In 1846 he received his medical doctorate, and at different stages of his career he was a professor of natural history, anatomy, and histology. He was a member of the Académie Nationale de Médecine (1858) and Academy of Science (1866).
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Dehydration is followed by a clearing agent (typically xylene although other environmental safe substitutes are in use) which removes the alcohol and is miscible with the wax, finally melted paraffin wax is added to replace the xylene and infiltrate the tissue. In most histology, or histopathology laboratories the dehydration, clearing, and wax infiltration are carried out in tissue processors which automate this process. Once infiltrated in paraffin, tissues are oriented in molds which are filled with wax; once positioned, the wax is cooled, solidifying the block and tissue.
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Histology of nasal polyp, magnification 25x (H&E; stain) On histologic examination, nasal polyps consist of hyperplastic edematous (excess fluid) connective tissue with some seromucous glands and cells representing inflammation (mostly neutrophils and eosinophils). Polyps have virtually no neurons. Therefore, the tissue that makes up the polyp does not have any tissue sensation and the polyp itself will not be painful. In early stages, the surface of the nasal polyp is covered by normal respiratory epithelium, but later it undergoes metaplastic change to squamous type epithelium with the constant irritation and inflammation.
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The Hippocrates Project began In 1987 in an unused microbiology laboratory by six medical students (Alan Simon, M.D.; Howard M. Karpoff, MD and others) and one member of the faculty, Martin Nachbar, MD (1937-2015). It was one of the early adopters of the use of computers and multimedia in education. Courseware was created, such as a computerized atlas of Histology in HyperCard and a multidimensional Neuroanatomy Atlas using SuperCard. Software expanded to include other courseware, digitized video, and 3-d simulations of surgery, such as Laparoscopic Cholecystectomy.
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Vittorio Marchi (1851-1908) Vittorio Marchi (30 May 1851, Novellara - 12 May 1908, Iesi) was an Italian neurologist and histologist. He studied pharmaceutical chemistry and medicine at the University of Modena, earning his doctorate in 1882.Vittorio Marchi in Dizionario Biografico – Treccani (biography) He was head of the histology laboratory at the psychiatric hospital of Reggio Emilia, and later director of the primary medical hospital in Iesi.Treccani.it Vittorio Marchi nell'Enciclopedia Treccani He was the creator of a popular osmium-based staining method ("Marchi stain") for the demonstration of degenerating nerve fibers.
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Costa was born in Turin, Italy, on 9 January 1940. In 1949 his family migrated to Argentina, where he attended San Martin high school and then in 1954 entered the public Italian High School Cristoforo Colombo of Buenos Aires, finishing the Scientific Lyceum in 1960. In his youth he was intrigued by science, even selling his bicycle so he could buy a microscope to study protozoa in ponds. He studied as an intern in the University of Turin's Department of Anatomy and Histology, working as a researcher under supervision of Giorgio Gabella.
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Christian August Voigt (21 August 1808 - 10 February 1890) was an Austrian anatomist born in Brody, Galicia. He studied medicine in Vienna, receiving his doctorate in 1841 with a dissertation titled, De systemate Intermedio vasorum eiusque radicibus. In Vienna, he was influenced by the work of anatomist Christian Joseph Berres (1796-1844). From 1847 to 1850, he was a professor at the surgical-medical college in Laibach, afterwards teaching classes in Lemberg (1850–54), Krakow (1854–61) and Vienna (1861–78), where he was a professor of anatomy and histology.
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An example of a physical theory that takes a deliberately macroscopic viewpoint is thermodynamics. An example of a topic that extends from macroscopic to microscopic viewpoints is histology. Not quite by the distinction between macroscopic and microscopic, classical and quantum mechanics are theories that are distinguished in a subtly different way. At first glance one might think of them as differing simply in the size of objects that they describe, classical objects being considered far larger as to mass and geometrical size than quantal objects, for example a football versus a fine particle of dust.
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GPS applications typically use icons to represent different categories of POI on a map graphically. A region of interest (ROI) and a volume of interest (VOI) are similar in concept, denoting a region or a volume (which may contain various individual POIs). In medical fields such as histology/pathology/histopathology, points of interest are selected from the general background in a field of view; for example, among hundreds of normal cells, the pathologist may find 3 or 4 neoplastic cells that stand out from the others upon staining.
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His interest was drawn toward experimental research, and so enrolled in the department of natural sciences where he joined the laboratory for two years, the same which had once been used by Arthur Van Gehuchten. It was during this time that he made his first scientific contributions: two publications on the histology of the nerve cell. After having a conversation with Désiré Mercier, founder of Leuven's laboratory of experimental psychology, was when he finally decided to dedicate himself to psychology. He began working under Armand Thiéry, who had been the laboratory director since 1894.
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He studied under Heinrich Wilhelm Waldeyer (1836-1921) at the University of Berlin, obtaining his medical doctorate in 1892 with a thesis on the ciliary body and iris of the reptilian eye. In 1898 he received his habilitation in Berlin, and in 1935 was appointed full professor of histology, embryology and anatomy at the institute of Hermann Stieve (1886-1952). Kopsch published numerous works on comparative anatomy and embryology, and with August Rauber (1841-1917) was co-author of the Lehrbuch und Atlas der Anatomie des Menschen. After Rauber's death, he was its sole author.
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Some of the most important anatomical information about dinosaur teeth is collected from polished, microscopically thin sections (histology), including the types of dental tissues present, tooth wear, tooth replacement patterns, how the teeth are attached, and the frequency of replacement. The actual material comprising a dinosaur tooth is not very different to teeth in modern animals. Most significant differences are in how the teeth fit together and continually regrew, with some examples shedding old teeth and others reabsorbing old teeth as they would grind down under chewing throughout a dinosaurs life.
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A stained histologic specimen, sandwiched between a glass microscope slide. Staining is a technique used to enhance contrast in samples, generally at the microscopic level. Stains and dyes are frequently used in histology (the study of tissue under the microscope) and in the medical fields of histopathology, hematology, and cytopathology that focus on the study and diagnoses disease at a microscopic level. Stains may be used to define biological tissues (highlighting, for example, muscle fibers or connective tissue), cell populations (classifying different blood cells), or organelles within individual cells.
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The Hertwig epithelial root sheath (HERS) or epithelial root sheath is a proliferation of epithelial cells located at the cervical loop of the enamel organ in a developing tooth. Hertwig epithelial root sheath initiates the formation of dentin in the root of a tooth by causing the differentiation of odontoblasts from the dental papilla. The root sheath eventually disintegrates with the periodontal ligament, but residual pieces that do not completely disappear are seen as epithelial cell rests of Malassez (ERM).Ten Cate's Oral Histology, Nanci, Elsevier, 2013, p.
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Robins moved to the psychiatric department at Washington University in St. Louis in 1949, initially as a pharmacology fellow working in the lab of biochemist Oliver H. Lowry, author of the most cited scientific paper ever (on a method for measuring proteins).A Tribute to Eli and Lee Robins - Citation Superstars. A Citationist Perspective on Biological Psychiatry Institute for Scientific Information, 1989 Throughout his career he published on brain neurochemistry and histology. He would be author on more than 175 peer-reviewed articles, including on suicide, hysteria, homosexuality and depression.
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Even after her retirement in 1967, Battle found innovative ways to teach and was one of the first instructors to use television, taping a series of lectures for the Natural Science Centre. Her research included examining the impact of pollutants on marine life and drinking water through the analysis of fertilized fish eggs. She was one of the first zoologists to actively apply laboratory research methods to marine problems, including histology and physiology methods. She also pioneered the use of fish eggs to study the effects of cancer-causing substances on cell development.
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The Heterostracans differed from other Paleozoic agnathan taxa both in the arrangement and histology of their scales. Most heterostracans had two plates which form a large dorsal shield and a large ventral shield, and had series of scales arranged in various patterns on the sides of their bodies, the exact pattern differing from one group to another. In a few primitive forms, such as Lepidaspis, the dorsal and ventral shields are composed of a mosaic of tiny scales. In most other known forms, though, these tiny scales have fused together to form the shield-plates.
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Castoreum Castoreum is a yellowish exudate from the castor sacs of mature beavers. Beavers use castoreum in combination with urine to scent mark their territory.Walro, J.M. and Svendsen, G.E., "Castor sacs and anal glands of the North American beaver (Castor canadensis): their histology, development, and relationship to scent communication" Journal of Chemical Ecology, Volume 8, Number 5 / May 1982, Department of Zoology and Microbiology, Ohio University,Müller-Schwarze, Dietland (1992). "Castoreum of beaver (Castor canadensis): function, chemistry and biological activity of its components" Chemical Signals in Vertebrates IV, 457–464, Plenum Press.
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The cells from giant-cell carcinomas are anaplastic, and show no evidence of cell maturation or differentiation, lacking the cytological and tissue architectural characteristics of squamous cell carcinoma, adenocarcinoma, neuroendocrine carcinomas, or other more differentiated lung cancer cell types. They tend to be highly pleomorphic (i.e. variable in characteristics), but are most often round and/or polygonal in shape, with a relatively low nuclear-to-cytoplasmic ratio. When associated with spindle cells, as they very frequently are in tumors with mixed histology, malignant giant cells tend to form loosely cohesive aggregate structures on cytological examination.
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Ficarra has a BSc (Hons) from the University of Sydney. Following graduation she became a senior tutor at the university in histology and physiology, teaching medical, dental, veterinary science and science students. As government affairs adviser to Merck Sharp and Dohme Australia, she assisted in obtaining federal government approval and reimbursement for many vital pharmaceuticals including the cervical cancer vaccine. During that time she was elected for three years to the executive of the NSW Liberal Party of which she has been a member for over 30 years.
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The diagnosis of DLBCL-CI is heavily dependent on patient history, presence of a tumor with the appropriate histology, and evidence indicating EBV infection. The patient should have a history of long-term chronic inflammation in a site that is known or thought to be sequestered from the immune system such as the pleural space, skin ulcer, or foreign body. The lesions, which generally are tumorous rather than infiltrative, should consist of large cells that resemble centroblasts, immunoblasts, or, less commonly, anaplastic, i.e. poorly differentiated, cells that are arranged in a diffuse pattern.
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DMF. Bulk powder is dark purple. Texas Red or sulforhodamine 101 acid chloride is a red fluorescent dye, used in histology for staining cell specimens, for sorting cells with fluorescent-activated cell sorting machines, in fluorescence microscopy applications, and in immunohistochemistry.Sulforhodamine 101 acid chloride Sigma-Aldrich product information Texas Red fluoresces at about 615 nm, and the peak of its absorption spectrum is at 589 nm. The powder is dark purple. Solutions can be excited by a dye laser tuned to 595-605 nm, or less efficiently a krypton laser at 567 nm.
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As expected, the mortality rates increase as the severity of the ARDS increases with mortality rates at approximately 35%, 40%, and 46% for mild, moderate, and severe, respectively. It has been revealed that patients with ARDS that show DAD on histology are at a high mortality rate of 71.9% compared to 45.5% in patients with ARDS but without DAD. Of the patients who succumb to ARDS, the most common cause of death is septic shock with multi organ dysfunction syndrome. Among survivors upon discharge, many will have impairments in their lung function.
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When he was studying in Vienna, during the height of the Crimean War, he attempted to join the army of Omar Pasha as a civil surgeon, but passport issues meant he was arrested instead. George Harley, 1863, by Camille Silvy In 1855 Harley was appointed lecturer on practical physiology and histology at University College London; and was also made curator of its anatomical museum. In 1856 he started private practice in Nottingham Place. In 1858 he was elected a fellow of the Chemical Society, and fellow of the College of Physicians of Edinburgh.
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The status of the histologic middle segment of the epididymis in reptiles is incompletely defined (Figure 1A). Considering the wide variation in the anatomical structures of the four orders (Crocodilia, Sphenodontia, Squamata, Testudines) of reptilian epididymides and the paucity of histologic studies that correlate anatomical structure to histology, the evolution of the middle segment in reptiles, if present, remains to be delineated. In contrast, extensive studies of the echidna epididymis show that the monotreme epididymis lacks a middle segment. It is only in metatherian and eutherian mammals that a middle segment has been extensively documented.
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Due to the causal relationship between H. pylori infection and MALT lymphoma, identification of the infection is imperative. Histological examination of GI biopsies yields a sensitivity of 95% with five biopsies, but these should be from sites uninvolved by lymphoma and the identification of the organism may be compromised by areas of extensive intestinal metaplasia. As proton-pump inhibition can suppress infection, any treatment with this class of drug should be ceased 2 weeks prior to biopsy retrieval. Serology should be performed if histology is negative, to detect suppressed or recently treated infections.
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At the end of the 1960s and beginning of the 1970s he became interested in studying the macromycetes from arid ecosystems of Mexico;Repositorio Atenea de la Facultad de Ciencias, UNAM: Macromicetos de las zonas áridas de México. II. Gasteromycetos in collaboration with Gastón Guzmán they became pioneers in this research area. At the same time he continued to describe the Mexican fungal flora from the Valley of Mexico. In 1965 he published a detailed study of the systematic, histology and ecology of the genus Helvella in the Valley of Mexico.
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Instead, these experimental grafts typically did not affect the speed of wound closure. In one case, however, a particular type of collagen graft led to significant delay of wound closure. Careful study of histology samples revealed that grafts that delayed wound closure induced the synthesis of new dermis de novo at the injury site, instead of forming scar, which is the normal outcome of the spontaneous wound healing response. This was the first demonstration of regeneration of a tissue (dermis) that does not regenerate by itself in the adult mammal.
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The reticular membrane (RM, also called reticular lamina or apical cuticular plate)Histology and Virtual Microscopy Learning Resources University of Michigan Medical School; accessed 4 Apr 2013 is a thin, stiff lamina that extends from the outer hair cells to the Hensen's cells.Radivoj V. Krstic. Human Microscopic Anatomy: An Atlas for Students of Medicine and Biology Springer, 1991; pp 554. . The RM is composed of "minute-fiddle-shaped cuticular structures" called the phalangeal extensions of the outer hair cells, interspaced with extensions coming from the outer phalangeal cells.
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He was born at Weimar, and educated at the University of Jena (1841–45). He subsequently became an associate professor at the University of Göttingen (1852), relocating to the University of Würzburg in 1858 as a full professor of pathological anatomy.biography @ Allgemeine Deutsche Biographie His investigations on pathological histology and teratology were widely noted. In 1854 he provided an early description of Charcot-Leyden crystals,Thorax 1986;41:503-507 Charcot-Leyden crystals and Curschmann spirals in asthmatic sputum and in 1862, described what would later become known as Meckel syndrome.
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At the same time, Dr. Marić also held the top Chair of the Histology Department at the Zootechnical- Veterinary School of the same university. He quickly became a respected scientist in Soviet Russia, publishing scientific articles and monographs in the field of mitosis and amitosis. Some Russian scientists are convinced that Milos Marić (in Russia known as Milos Milosevic Maric) laid the foundations of the medical field that is now called cloning. Along with these studies, Marić worked and prepared for the study of the nervous system, but was interrupted by the Great Patriotic War.
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In 1893, John Henry Comstock and Simon Henry Gage founded the Comstock Publishing Company in order to make textbooks on microscopy, histology, and entomology available at a reasonable price to students and to publish the works of Anna Botsford Comstock on nature study. Comstock, through his own work and that of his students, had a significant influence in the development of entomology departments throughout the United States. He suffered a stroke on August 5, 1926, and continued to live as an invalid until his death on March 20, 1931.
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In 1847 he received his habilitation at Würzburg, where from 1858 he served as a full professor of topographical and comparative anatomy. As an instructor, he also taught classes in systematic anatomy, histology and microscopy.Deutsche Biographie Heinrich Müller In 1851 Müller noticed the red color in rod cells now known as rhodopsin or visual purple, which is a pigment that is present in the rods of the retina. However, Franz Christian Boll (1849–1879) is credited as the discoverer of rhodopsin because he was able to describe its "visual pigment cycle".
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After completing the training program, students travel to their assigned regional site to complete the first of three, one-week clinical "intersessions." These clinical experiences are continued at the beginning of every quarter during years one and two, and are also where students will complete their third- and fourth-year clinical clerkships. After returning to the Spokane campus in the fourth week, students begin their first curriculum block, anatomy and histology. Students split their time between classroom instruction, cadaver lab, and self-directed learning through weekly small group case-based-learning sessions.
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Gross anatomy also includes the branch of superficial anatomy. Microscopic anatomy involves the use of optical instruments in the study of the tissues of various structures, known as histology, and also in the study of cells. The history of anatomy is characterized by a progressive understanding of the functions of the organs and structures of the human body. Methods have also improved dramatically, advancing from the examination of animals by dissection of carcasses and cadavers (corpses) to 20th century medical imaging techniques including X-ray, ultrasound, and magnetic resonance imaging.
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Medical studies in France are organized as follow: Description of medical studies in France Right after graduating from high school with a baccalaureat, any student can register at a university of medicine (there are about 30 of them throughout the country). At the end of first year, an internal ranking examination takes place in each of these universities in order to implement the numerus clausus. First year consists mainly of theoretical classes such as biophysics and biochemistry, anatomy, ethics or histology. Passing first year is commonly considered as challenging and requires hard and continuous work.
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The diagnosis of IVNK/TL depends upon obtaining histology findings in the skin and/or other involved tissue that resembles that seen in IVBCL except that the malignant lymphocytes are not B-cells but rather: 1) NK-cells as evidenced by their expression of NK-cell selective marker proteins (e.g. CD3e, CD2, CD30, CD43, CD56, and/or CD79), expression of granule-bound enzymes (e.g. granzyme B), and expression of EBV proteins (e.g. Epstein–Barr virus latent membrane protein 1 and EBV- produced small RNAs); but not the expression of B-cell (e.g.
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Toponomics is a discipline in systems biology, molecular cell biology, and histology concerning the study of the toponome of organisms. It is the field of study that purposes to decode the complete toponome in health and disease (the human toponome project)—which is the next big challenge in human biotechnology after having decoded the human genome. A toponome is the spatial network code of proteins and other biomolecules in morphologically intact cells and tissues. The spatial organization of biomolecules in cells is directly revealed by imaging cycler microscopy with parameter- and dimension- unlimited functional resolution.
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In 1910, he acquired a valuable house in España Avenue and extended as far as the railroad, present day Gondra Street. Andrés Barbero was born in Asunción on July 28, 1877. He finished his pharmacy studies in 1898 and, in 1903, his medicine studies, being among the first people who received their medical diploma in Paraguay. His wealthy position allowed him to dedicate himself completely to teaching, beginning with the National School and later in the same Medicine University, in the subjects of physical medicine, physiology and histology.
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In an analysis of the shell bone histology of two stem trionychians, the Adocidae and Nanhsiungchelyidae, it was found that the shell bones of the nanhsiungchelyids have a diploe structure and cortical bone layers that frame the interior cancellous bone. Osteoderms of the Basilemys have pronounced and elaborate sculpturing patterns. The sample from the North America Basilemys showed a highly organized “spindle-shaped pattern” of ornamentation. In addition, the sculpturing pattern of Basilemys is made of irregular grooves and pits of external bone surface which is what is typically described as the “pock-mark” surface.
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Histology slide of a solar lentigo Differently from the melanotic nevi and the verrucous nevi on the skin, age spots change in color and in shape with time. Michelitsch and Michelitsch propose an hypothesis inspired by their misrepair-accumulation aging theory for the development of age spots. They propose that aged basal cells contain lipofuscin bodies cannot be removed and might promote the aging of neighboring, generating a feedback loop whereby more and more neighbor cells become aged and lipofuscin-containing. Such cells might then aggregate into a spot with an irregular shape.
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This type of microscopy confirmed that the primary adenoma cell cultures keep their physiological characteristics in vitro, which matched the histology inspection. Moreover, cell cultures of human pituitary adenomas were viewed by light microscopy and immunocytochemistry, where these cells were fixed and immunolabeled with a monoclonal mouse antibody against human GH and a polyclonal rabbit antibody against PRL. This is an example of how a immunolabeled cell culture of pituitary adenoma cells that were viewed via light microscopy and by other electron microscopy techniques can assist with the proper diagnosis of tumors.
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Starting in approximately the 1970s into the present day analytical chemistry has progressively become more inclusive of biological questions (bioanalytical chemistry), whereas it had previously been largely focused on inorganic or small organic molecules. Lasers have been increasingly used in chemistry as probes and even to initiate and influence a wide variety of reactions. The late 20th century also saw an expansion of the application of analytical chemistry from somewhat academic chemical questions to forensic, environmental, industrial and medical questions, such as in histology. Modern analytical chemistry is dominated by instrumental analysis.
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The cell theory of Matthias Schleiden and Theodor Schwann (1838/39) generated a debate about the behaviour of cancer cells, the use of the microscope, and its relevance to cancer diagnosis. Not all pathologists believed that cancer cells were distinctive or that cancer could be diagnosed by looking at a collection of cells (histology) rather than individual cells (cytology). The definition of cancer did not incorporate its morphological features until many years later. It had instead relied on looking solely at the spread of the cancer, that is, its "ability to invade locally and metastasize".
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A cementoblast is a biological cell that forms from the follicular cells around the root of a tooth, and whose biological function is cementogenesis, which is the formation of cementum (hard tissue that covers the tooth root). The mechanism of differentiation of the cementoblasts is controversial but circumstantial evidence suggests that an epithelium or epithelial component may cause dental sac cells to differentiate into cementoblasts, characterised by an increase in length.Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 207 Other theories involve Hertwig epithelial root sheath (HERS) being involved.
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He studied medicine there for three months before continuing his studies in Budapest. Klein worked as an instructor in histology and pathology from 1945 to 1947 at the Pázmány Péter University; it was while working there, in July 1947, that he met his future wife, Eva Fischer. Shortly after meeting her, he and a group of students were invited by a Jewish student club in Sweden to visit Stockholm and Gothenburg, where Klein was introduced to the Karolinska Institute. After talking to Torbjörn Caspersson, he was offered a job there as a research assistant.
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As with any cancer, the treatment and prognosis of HCC vary depending on the specifics of tumor histology, size, how far the cancer has spread, and overall health. The vast majority of HCC occurs in Asia and sub- Saharan Africa, in countries where hepatitis B infection is endemic and many are infected from birth. The incidence of HCC in the United States and other developing countries is increasing due to an increase in hepatitis C virus infections. It is more common in males than females for unknown reasons.
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Meyer was born in Basel (Switzerland) to Theodor Meyer, 1852–1934, (a „Meyer zum Pfeil”), international cigar merchant, and Sophie, née Lichtenhahn, teacher, 1857-1936. Karl Friedrich had two younger sisters. Meyer began his studies in 1902 at the University of Basel and soon moved to the University of Zurich where he concentrated on biology, zoology, histology, and laboratory techniques. He was greatly fostered by Heinrich Zangger, professor of comparative anatomy (and later the first professor of Medical Law in Zurich), who sent him to work with leading scientists in Munich and Bern.
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Anton Weichselbaum (8 February 1845 – 23 October 1920) was an Austrian pathologist and bacteriologist born near the town of Langenlois. Weichselbaum was among the first scientists to recognize the importance of bacteriology for the field of pathological anatomy. In 1869, he received his medical doctorate in Vienna, and subsequently worked as an assistant to pathological anatomist Josef Engel (1816–1899). In 1885, he was appointed an associate professor of pathological histology and bacteriology, and from 1893 to 1916, he was director of the pathological-anatomical institute at the University of Vienna.
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Retina (part of the eye) stained with hematoxylin and eosin, cell nuclei stained blue-purple and extracellular material stained pink. Hematoxylin and eosin stain or haematoxylin and eosin stain (often abbreviated as: H&E; stain or HE stain) is one of the principal tissue stains used in histology. It is the most widely used stain in medical diagnosis and is often the gold standard. For example, when a pathologist looks at a biopsy of a suspected cancer, the histological section is likely to be stained with H&E.
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Rack of slides being removed from a bath of hematoxylin stain. There are many ways to prepare the hematoxylin solutions (formulation) used in the H&E; procedure, in addition, there are many laboratory protocols for producing H&E; stained slides, some of which may be specific to a certain laboratory. Although there is no standard procedure, the results by convention are reasonably consistent in that cell nuclei are stained blue and the cytoplasm and extracellular matrix are stained pink. Histology laboratories may also adjust the amount or type of staining for a particular pathologist.
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A comparison between modern turtles and Proganochelys found that it was not likely that stem- turtles had differentiated into specialized ecologies such as open water swimmers or solely terrestrial turtles in the Late Triassic period. If this is the case, a freshwater habitat would be the most likely environment for Proganochelys to have lived in. On the other hand, it is noted that some believe Proganochelys were solely terrestrial. Shell bone histology of extant turtles revealed congruence with terrestrial turtles for the earliest basal turtles, including Proganochelys, taxa in one study.
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Gross anatomy is the study of anatomy at the visible or macroscopic level. The counterpart to gross anatomy is the field of histology, which studies microscopic anatomy. Gross anatomy of the human body or other animals seeks to understand the relationship between components of an organism in order to gain a greater appreciation of the roles of those components and their relationships in maintaining the functions of life. The study of gross anatomy can be performed on deceased organisms using dissection or on living organisms using medical imaging.
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Birkett was admitted a Member of the Royal College of Surgeons on 1837-10-06, and appointed a Demonstrator of Anatomy at the same time, a post that he held until 1847. In 1844 he was elected Fellow of the R.C.S. without examination, and by 1845/1846 he was giving demonstrations in microscopic anatomy on weekday evenings, the first instruction in histology given at the medical school. In 1847 he was appointed to the position of making the hospital's post-mortem examinations. In May 1849 he was elected assistant surgeon.
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In 1925, she went to the United States where she worked with Ross G. Harrison of Yale University carrying out experimental work on the axolotl or Mexican salamander. On returning to Oslo two years later, she discovered how an arm could grow out of an unexpected place on the body of the axolotl. Teaching formed an important part of Ruud's activities at the laboratory. In addition to assisting Bonnevie with her zoology course which covered anatomy, embryology and cytology, Ruud was responsible for a one-year practical course and for lectures on histology.
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Once in the brain, the virus and the host's inflammatory response disrupt neural function, leading to illness and complications, many of which frequently are neurological in nature, such as impaired motor skills and altered behavior. Viral encephalitis can be diagnosed based on the individual's symptoms, personal history, such as travel history, and different clinical tests such as histology, medical imaging, and lumbar punctures. A differential diagnosis can also be done to rule out other causes of the encephalitis. Many encephalitic viruses often have characteristic symptoms of infection, helping to aid diagnosis.
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Studies of bone histology show that Kosmoceratops grew rapidly and had an elevated metabolism, similar to modern birds and mammals. The teeth of ceratopsids were adapted to processing fibrous plants; coprolites (fossilized dung) from the Kaiparowits Formation that contain wood may have been produced by ceratopsids. The functions of ceratopsian frills and horns have been debated, including display, combat, and species recognition. The Kaiparowits Formation dates to the late Campanian age and was deposited on Laramidia, an island continent, when North America was divided at the center by the Western Interior Seaway.
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Tibial histology of MOR 2919 The describing article also published the result of histological research of the bone structure of the left shinbone of the type specimen. This bone showed fourteen LAGs, lines of arrested growth, that likely represented yearly seasons of low food intake. The age of the holotype would thus be about fourteen years. The distance between the lines indicated this individual had not yet reached its maximum size, but closely approached it, proof that it was not simply a subadult Brachylophosaurus specimen with a small crest.
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HIV-associated nephropathy (HIVAN) refers to kidney disease developing in association with infection by human immunodeficiency virus, the virus that causes AIDS. The most common, or "classical", type of HIV-associated nephropathy is a collapsing focal segmental glomerulosclerosis (FSGS), though other forms of kidney disease may also occur. Regardless of the underlying histology, kidney disease in HIV-positive patients is associated with an increased risk of death. HIVAN may be caused by direct infection of the kidney cells by HIV, with resulting kidney damage through the viral gene products.
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Use of alcian blue has historically been a popular staining method in histology especially for light microscopy in paraffin embedded sections and in semithin resin sections. The tissue parts that specifically stain by this dye become blue to bluish-green after staining and are called "Alcianophilic" (comparable to "eosinophilic" or "sudanophilic"). Alcian blue staining can be combined with H&E; staining, PAS staining and van Gieson staining methods. Alcian blue can be used to quantitate acidic glycans both in microspectrophotometric quantitation in solution or for staining glycoproteins in polyacrylamide gels or on western blots.
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He studied histology under Justin Marie Jolly at the Collége de France in Paris,Notice nécrologique sur Jacques Millot par Jean Dorst. (in French) earning his medical doctorate in 1922. In 1931 he became a professor of physiological anthropology, and in 1943, he was appointed chair of comparative anatomy at the Muséum national d’Histoire naturelle, a position he kept up until 1960.Prosopo Sociétés savantes de France Afterwards, he was a professor of ethnology at the natural history museum as well as director of the Musée de l'Homme (1960–67).
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The holotype specimen was likely not fully grown when it died. The histology of the holotype humerus, which shows a lack of an external fundamental system (an outer layer of bone found only in fully-grown vertebrates) and abundant fast- deposited or still-growing woven tissue in the primary fibrolamellar bone of the outer bone cortex, led Lacovara et al. (2014) to determine that the specimen was still growing when it died. It remains unknown how large this individual would have grown had it not died when it did.
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The falciform ligament can become canalised if an individual is suffering from portal hypertension. Due to the increase in venous congestion, blood is pushed down from the liver towards the anterior abdominal wall and if blood pools here, will result in dilatation of veins around the umbilicus. If these veins radiate out from the umbilicus, they can give the appearance of a head (the umbilicus) with hair of snakes (the veins) - this is referred to as caput medusae.Misdraji J, Embryology, anatomy, histology, and developmental anomalies of the liver.
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In 1990 Sokolov became a foreign honorary member of the American Academy of Arts and Sciences. His research focused on ecological morphology, electron microscopy and histology, the hydrodynamics of swimming and environmental physiology, bionics and telemetry, radio-ecology and ecotoxicology and ground-based environmental monitoring. He showed great interest in environmental law and wildlife management issues, conservation of biodiversity and rare species, the history of zoology and environmental education. During his work Sokolov organised numerous zoological expeditions in the Soviet Union, as well as abroad to Bolivia, Cuba, Ethiopia, Mexico, Mongolia, Peru and Vietnam.
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Born in Copenhagen on 13 December 1955, Dahlin is the daughter of the physician Edgar Frankovitch Dahlin and Birte Hauge Andersen, a histology technician. She studied at the Royal Danish Academy of Fine Arts (1978–84) under Sven Dalsgaard, Freddie A. Lerche and Hein Heinsen. Dahlin first collaborated with the other Wild Youth artists, creating dynamic, expressive works but in the mid-1980s, she became interested in experimenting with shifts in perspective. Her 1988 work I forgot to Remember to Forget draws on traditional Chinese painting which is free of perspective.
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In some cases, DCIS may become invasive and spread to other tissues, but there is no way of determining which lesions will remain stable without treatment, and which will go on to become invasive. DCIS encompasses a wide spectrum of diseases ranging from low-grade lesions that are not life-threatening to high-grade (i.e. potentially highly aggressive) lesions. DCIS has been classified according to the architectural pattern of the cells (solid, cribriform, papillary, and micropapillary), tumor grade (high, intermediate, and low grade), and the presence or absence of comedo histology.
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In 1893, Stewart went to Harvard University as instructor in physiology following an invitation from Henry P. Bowditch. In 1894 he was appointed professor of physiology and histology at Western Reserve University School of Medicine, in Cleveland, Ohio, where he remained with the exception of the years 1903–1907 during which he was professor of physiology at the University of Chicago. In 1907 he became professor of experimental medicine and director of the H.K. Cushing Laboratory of Experimental Medicine; he was also clinical physiologist to Lakeside Hospital, Cleveland.
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It will deal exclusively with basic veterinary disciplines such as Anatomy, Histology, Microbiology and Physiology as well as modules in Animal Science, Pasture Science and Professional Life. The third year will be devoted to the causes and effects of disease and will include modules on Infectious Diseases, Parasitology, Toxicology, Pharmacology, Organ Pathology and Professional Life. In the fourth year, the student will be introduced to modules aimed at diagnostics and therapeutics and in the first semester of the fifth year with community interaction. Specific species-directed modules in these semesters will also be presented.
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Histochemistry and Cell Biology is a peer-reviewed scientific journal in the field of molecular histology and cell biology, publishing original articles dealing with the localization and identification of molecular components, metabolic activities, and cell biological aspects of cells and tissues. The journal covers the development, application, and evaluation of methods and probes that can be used in the entire area of histochemistry and cell biology. The journal is published by Springer Science+Business Media and the official journal of the Society for Histochemistry. Earlier names of the journal are Histochemie and Histochemistry.
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Frank B. Mallory, James H. Wright. Pathological Technique : a practical manual for workers in pathological histology and bacteriology : including directions for the performance of autopsies and for clinical diagnosis by laboratory methods. First published 1897 He also studied the function of histiocytes, he confirmed that the whooping cough bacillus discovered by Jules Bordet was the causative agent, and he worked on improvements in classification of tumours, particularly meningiomas, and cirrhosis of the liver. He was president of the American Association of Pathologists and Bacteriologists in 1910, and was its treasurer from 1911 to 1940.
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The Javelina Formation is a geological formation in Texas. Dating has shown that the strata date to the Maastrichtian stage of the Late Cretaceous, approximately 70 to 66.5 million years old. The middle part of the formation has been dated to about 69 million years ago plus or minus 1 Ma and the top situated near the Cretaceous–Paleogene boundary (in the overlying Black Peaks FormationWoodward, H. N. (2005). Bone histology of the sauropod dinosaur Alamosaurus sanjuanensis from the Javelina Formation, Big Bend National Park, Texas.), dated to 66 Ma ago.
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Some researchers posit that it must not be macrophages that are involved, as they could not appropriately discriminate between the varied array of opsonized entities as necessary, and that, in reality, the properties ascribed to the macrophage in the initiation phase of the inflammatory response actually belong to the lymphatic dendritic cell. It is unclear, however, if the latter is a distinct population of cells or if it is merely a particularly specialized strain of macrophage.Ross, MH, Histology: A Text and Atlas, 3rd Edition. Philadelphia: Lippincott, Williams and Wilkins, 1995. page 339.
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It is the first turtle to be discovered in South American continental deposits of that age, and shows a unique combination of traits (shared and derived), who allows the recognition of this fossil as a new genus. Despite that, more remains are needed to clarify its phylogenetic relationships. The estimated length of carapace is 18 cm. The histology of its plates, a shell that is dorsoventrally low, and the paleoenvironment proposed for the Tacuarembó Formation (permanent and temporary streams and lakes), support the ecology of this genus as semiaquatic and mainly aquatic turtles.
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The inorganic dye ammoniated ruthenium oxychloride, also known as ruthenium red, is used in histology to stain aldehyde fixed mucopolysaccharides. Ruthenium red (RR) has also been used as a pharmacological tool to study specific cellular mechanisms. Selectivity is a significant issue in such studies as RR is known to interact with many proteins. These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase, mitochondrial Ca2+ uniporter, tubulin, myosin light- chain phosphatase, and Ca2+ binding proteins such as calmodulin.
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In 1991, they reported that the bones of old individuals contained the highest amounts of lead and iron, while those in younger animals were lower. A study of the bone histology of various dinosaurs in 2000, by biologists John M. Rensberger and Mahito Watabe, revealed that the canaliculi (channels which connect bone cells) and collagen fibre bundles of Gallimimus and other ornithomimids were more akin to those in birds than mammals, unlike those of ornithischian dinosaurs, which were more similar to mammals. These differences may have been related to the process and rate at which bone formed.
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Victor Babeș (; 28 July 1854 in Vienna – 19 October 1926 in Bucharest) was a Romanian physician, bacteriologist, academician and professor. One of the founders of modern microbiology, Victor Babeș is author of one of the first treatises of bacteriology in the world – Bacteria and their role in pathological anatomy and histology of infectious diseases, written in collaboration with French scientist Victor André Cornil in 1885. In 1888, Babeș underlies the principle of passive immunity, and a few years later enunciates the principle of antibiosis. He made early and significant contributions to the study of rabies, leprosy, diphtheria, tuberculosis and other infectious diseases.
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As for other lung cancer subtypes, lung adenocarcinoma incidence is strongly associated with smoking. Incidence of pulmonary adenocarcinoma has been increasing in many developed Western nations in the past few decades, with a share reaching 43.3% of all lung cancers in the US as of 2012, thus replacing squamous cell lung carcinoma as the most common type of lung cancer. This can be largely attributed to the decreasing smoking rates, which favors the adenocarcinoma histology. Indeed, although smoking is still its strongest risk factor, lung adenocarcinoma is by far the most common among lifelong non-smokers (<100 cigarettes in a lifetime).
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Normal squamous cells Dysplastic cells Dysplasia is any of various types of abnormal growth or development of cells (microscopic scale) and/or organs (macroscopic scale), and/or the abnormal histology or anatomical structure presumably resulting from such growth. Dysplasias on a mainly microscopic scale include epithelial dysplasia and fibrous dysplasia of bone. Dysplasias on a mainly macroscopic scale include hip dysplasia, myelodysplastic syndrome, and multicystic dysplastic kidney. In one of the modern histopathologic senses of the term, dysplasia is sometimes differentiated from other categories of tissue change including hyperplasia, metaplasia, and neoplasia, and dysplasias are thus generally not neoplastic (not cancerous).
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Forensic pathologists receive specialized training in determining the cause of death and other legally relevant information from the bodies of persons who died suddenly with no known medical condition, those who die from non-natural causes, as well as those dying as a result of homicide, or other criminally suspicious deaths. A majority of the forensic pathologists cases are due to natural causes. Often, additional tests such as toxicology, histology, and genetic testing will be used to help the pathologist determine the cause of death. Forensic pathologists will often testify in courts regarding their findings in cases of homicide and suspicious death.
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The boundary between the necrotic center and the outer fibrous shell is made up of the characteristic feature of the nodule, which is known as a cellular palisade. The palisade is a densely packed layer of macrophages and fibroblasts which tend to be arranged radially, like the seeds of a kiwifruit or fig. Further out into the fibrous shell there is a zone that contains T cells and plasma cells in association with blood vessels. The histology of pulmonary nodules are similar to that of subcutaneous nodules, with central necrosis surrounded by palisading macrophages and inflammatory infiltrate.
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By 2012, there were 22 independent research programs plus core facilities in computational biology, cytometry, electron microscopy, histology, imaging, microscopy, molecular biology, proteomics and screening. Currently, the institute is home to over 550 members, including around 350 scientists, research associates, technicians and scientific support staff. Research at the Stowers Institute is primarily funded through the Hope Shares Endowment, most of which is the product of the Stowers’ generosity. The Institute receives additional competitive grant funding from the National Institutes of Health, the Howard Hughes Medical Institute, the American Cancer Society, the March of Dimes and other entities.
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Launois published several articles in the field of histology, but is primarily known for his studies involving the pituitary gland. His name is lent to "Launois' syndrome", which is also referred to as pituitary gigantism.Pierre Émile Launois, Études biologiques sur les géants 1904 In 1910, with M. Cléret, he described "syndrome hypophysaire adiposo-génital", known today as adiposogenital dystrophy, a disorder associated with an adenohypophysial tumour or lesions of the hypothalamus.Launois-Cléret syndrome @ Who Named ItMondofacto Dictionary (definition of eponym) With Raoul Bensaude (1866–1938), he described multiple symmetrical lipomatosis, a disease sometimes known as "Launois-Bensaude syndrome".
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Tong(1999), 68 The Association requested that she remain single during her time at medical school and for several years after her graduation, in order to focus on her practice. At the WMCP, LaFlesche studied chemistry, anatomy, physiology, histology, pharmaceutical science, obstetrics, and general medicine, and, like her peers, did clinical work at facilities in Philadelphia alongside students from other colleges, both male and female.Morantz-Sanchez (1985), 75 While attending medical school, LaFlesche changed her appearance. She began to dress like her white classmates and wore her hair in a bun on the top of her head as they did.
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Ru Group, German Klimenko, founder of LiveInternet, and Maelle Gavet, Head of Ozon.ru. Making a speech, the President used a tool for planting trees called Passion Fruit. Vladimir Putin promised to support Key to Life, a system of rapid communication with physicians, and gave instructions on the subject of integrating IIDF's projects into existing state mechanisms. These instructions referred to Angry Citizen, a system of processing applications submitted by citizens; Unim Histology, a system of remote diagnosis of cancer; Easy Ten, an application for studying English; and Micronet, an accounting and data systematisation system for consumption of public resources.
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Beutner in 2012 Ernst H. Beutner (August 27, 1923 – June 10, 2013) was a German-born microbiologist who discovered the role of autoimmunity in pemphigus and pemphigoid using self-designed immunofluorescent methods. For this achievement, he is often regarded as the "Founder of Immunodermatology".Thivolet, Jean; Jablonska, Stefania; Clinics in Dermatology , Volume 19 (5);Elsevier–Sep 1, 2001; Bullous disorders: from histology to molecular biologyJournal of Cutaneous Medicine And Surgery: Incorporating Medical and Surgical Dermatology Volume 6, Number 2, 155-206 He was the author or co-author of over 10 papers, which were each cited over 100 times.
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Meynert's work was largely focused on brain anatomy, pathology and histology, including the mapping of its intricate pathways and topography. He made many contributions involving the study of the cellular architecture of the brain and is often considered to be the founder of cerebral cortex cytoarchitectonics. Meynert developed theories in regards to correlations between neuroanatomical and mental processes. He conceptualized that a coupling between one mental association and its temporal successor as a literal contact between cortical nerve cells linked to one other by nerve fibers, and a series of cortical associations could therefore be construed as being a "train of thought".
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The neural canals in its neck vertebrae gradually become taller towards the back of the neck, which may be a distinguishing trait. Unlike the Lagerpetidae or Ornithodira, the hindlimbs of Teleocrater are not adapted for running; the metatarsal bones are not particularly elongated. Also unlike lagerpetids and ornithodirans, Teleocrater inherited the more flexible ankle configuration present ancestrally among archosaurs, suggesting that the same configuration was also ancestral to Avemetatarsalia but was lost independently by several lineages. Histology of the long bones of Teleocrater indicates that it had moderately fast growth rates, closer to ornithodirans than crocodilians and other pseudosuchians.
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Patients with this disorder may have detectable levels of circulating hepatitis C virus. The histology of the lesions in EMZL associated with hepatitis C virus infection is typical of EMZL although the genomic abnormalities in the disorders malignant cells has not been well- defined beyond their expression of the t(14;18) chromosome translocation in a significant number of cases. Treatment of this disease had relied on eradicating the virus using peginterferon-alfas, interferon-alpha-like drugs to mobilize the hosts' immune systems. This treatment cured the viral infection in ~50% and produced lymphoma remissions in <50% of cases.
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In children NMZL has been classified by the World Health Organization (2016) as a separate variant of NMZL based on its presentation, histology of the involved lymph nodes, and clinical course. Of the >60 published cases, 95% of Pediatric NMZL cases occurred in adolescent boys with >90% of cases presenting as an asymptomatic, localized (Stage I/II) disease involving enlargement of the lymph nodes of the head and neck regions. These cases showed no associations with autoimmune or pathogen-induced inflammatory diseases. All of these findings contrast with those seen in extranodal marginal zone lymphomas occurring in children.
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This also involved a large amount of histology and the overall supervision of a laboratory dealing with 40-60,000 general bacteriological specimens and 2-4000 Wasserman and Kahn tests annually. After the outbreak of Sino-Japanese hostilities in 1932 and 1937 normal services were dislocated and Blakelock was seconded for refugee work which included the evacuation and reorganization of hospitals. He assisted on two occasions in the complete evacuation of two large hospitals while under shell fire. Blakelock supervised inoculation, sanitary and vaccination measures in refugee camps and the distribution of American Red Cross supplies of milk and food to refugees.
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Paul Oscar Blocq (1860–1896, page 1.) was a French pathologist who is remembered for his neuropathological work done with Jean-Martin Charcot (1825-1893) and Gheorghe Marinescu (1863-1938) at the Salpêtrière in Paris. Blocq and Marinescu were the first physicians to describe extracellular neuritic plaque deposits in the grey matter of the brain. Also the two identified a case of Parkinsonian tremor caused by a tumor in the substantia nigra of the brain. With Marinescu and bacteriologist Victor Babeş (1854-1926), Blocq published an important work on the pathological histology of the nervous system titled Atlas der pathologischen Histologie des Nervensystems.
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Later on, he served as an assistant to François Jules Pictet de la Rive at the Geneva Academy, where in 1862 he became a professor of comparative anatomy. He was a regular contributor to the Archives des sciences physiques et naturelles.Claparède, René-Edouard Historischen Lexikon der Schweiz Statue of René-Édouard Claparède, at place Claparède in Geneva His main research dealt with the structure of infusoria, the anatomy of annelids, the histology of earthworms, the embryology of arthropods and the evolution of spiders. Species with the epithet of claparedii commemorate his name, an example being the sea anemone Edwardsia claparedii.
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In 1934 she left Columbia and until 1937 worked in the Department of Histology and Embryology at the Lithuanian University of Health Sciences. In 1938 she conducted important experiments which involved exposing female guinea pig foetuses to testosterone. She showed for the first time that this can give rise to an increase of masculine sexual behavior in adulthood. Danchakoff published many books as well as scientific papers, possibly her last publications being Le sexe; rôle de l'hérédité et des hormones dans sa réalisation in 1949 and Effects of cancer provoking chemical substances on gravid guinea pigs and their fruits in 1950.
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At this School, García-Austt set up an Integral Course of the Nervous System which included faculty from the physiology, biophysics, histology, anatomy and pharmacology departments. In 1959, García-Austt created the Neurophysiology Laboratory at the "Instituto de Neurología y Neurocirugía" of the School of Medicine. He worked until 1973, when he moved to Spain. The laboratory's research included: #Evoked potentials in humans and their relationship with attention and perception; # Regulating mechanisms of sensory, auditive, visual and somesthetic inputs; # Recording and electrical stimulation during brain surgery in humans; # Oxygen pressure variation during sleep; # Physiology and physiopathology of the intracranial pressure.
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Following the family tradition, he was admitted to study medicine at the University of Leiden in 1865 but his father thought he was too young and let him join after a year spent at home on private studies. During his studies at the University of Leiden, his research interests were sparked by Adriaan Heynsius who in turn had trained under Gerrit Jan Mulder. He also took an interest in histology under F.C. Donders, he joined the University of Utrecht. He received his license to practice medicine in 1872 and managed his father's practice while his parents vacationed abroad.
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He was the author of numerous > papers and studied such subjects as the water supplies of Trinidad; the > histology of Aedes and Anophole (sic = Anopheles) mosquitos; sickle-cell > anaemia; and the mosquito transmission of Venezuelan Equine > Encephalomeyelitis Virus in Trinidad. But he will best be remembered in the > annals of medical history along with Louis Pasteur for his contributions to > the study of rabies. His research on bat rabies has been considered by > rabies investigators over the world to be a classic of epidemiological > studies and has had a profound influence on all subsequent studies up to the > present time.Greenhall (1963), p. 14.
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The anatomy lecture room at the Woman’s Medical College of New York Infirmary, Frank Leslie's Illustrated Newspaper, April 16, 1870. Library of Congress. In 1872, Cushier graduated from the Woman's Medical College of the New York Infirmary for Women and Children and completed a year and a half of further studies at the University of Zurich researching pathological and normal histology, since this field of research was not open to women in the United States at that time. Cushier was employed by the Infirmary as a gynecologist and surgeon, becoming known for her expertise in both fields.
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In humans, enamel varies in thickness over the surface of the tooth, often thickest at the cusp, up to 2.5 mm, and thinnest at its border with the cementum at the cementoenamel junction (CEJ).Ten Cate's Oral Histology, Nanci, Elsevier, 2013, page 122 The normal color of enamel varies from light yellow to grayish (bluish) white. At the edges of teeth where there is no dentin underlying the enamel, the color sometimes has a slightly blue tone. Since enamel is semitranslucent, the color of dentin and any material underneath the enamel strongly affects the appearance of a tooth.
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A key strength of MSOT is its ability to resolve the photoechoes obtained in response to excitation with different wavelengths of illuminating light. Since the photoechoes depend on the optical absorption characteristics of molecules within the target tissue (or added to the tissue), MSOT can image the distributions of specific photoabsorbing molecules. The endogenous photoabsorbers most often imaged are oxy- and deoxy- hemoglobin, key players in oxygen metabolism, myoglobin, lipids, melanin and water. Several exogenous contrast agents have also been used in MSOT, including some common histology dyes, fluorescent dyes, novel metal-based agents and non-metallic nanoparticles.
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When the cementoid reaches the full thickness needed, the cementoid surrounding the cementocytes becomes mineralized, or matured, and is then considered cementum. Because of the apposition of cementum over the dentin, the dentinocemental junction (DCJ) is formed.Illustrated Dental Embryology, Histology, and Anatomy, Bath-Balogh and Fehrenbach, Elsevier, 2011, page 170-171 After the apposition of cementum in layers, the cementoblasts that do not become entrapped in cementum line up along the cemental surface along the length of the outer covering of the periodontal ligament. These cementoblasts can form subsequent layers of cementum if the tooth is injured.
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Secoisolariciresinol diglucoside slows the growth of human breast cancer in mice. Secoisolariciresinol diglucoside may different roles in people. For example, due to 400-500Da size limit for Blood–Brain Barrier permeability, in one assessment of a Grade IV histology group of adult patients diagnosed with malignant glioma, high intake of secoisolariciresinol (for highest tertile compared to lowest tertile, in all cases) was associated with poorer survival. In rabbits, SDG reduced hypercholesterolemic atherosclerosis and this effect was associated with a decrease in serum cholesterol, LDL-C, and lipid peroxidation product and an increase in HDL-C and antioxidant reserve.
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From the date of his removal to New York he took a leading position in his profession, making a specialty of the diseases of women, and particularly of ovariotomy. His treatise on Ovarian Tumors, published in 1872, was the standard authority on that subject. He also published in 1854 a work on Human Histology, and was a frequent and valued contributor to the medical journals. In 1872 he was elected Professor of Gynaecology in Dartmouth College, and in 1814 Gynaecology was made a separate chair in Bellevne Hospital Medical College, N. Y., and he was elected the first Professor.
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One research study found that pyridoxamine specifically reacts with the carbonyl group in Amadori products, but inhibition of post- Amadori reactions (that can lead to advanced glycation endproducts) is due in much greater part to the metal chelation effects of pyridoxamine. A variety of preclinical studies in animal models of diabetes indicated that pyridoxamine improved kidney histology comparable or superior to aminoguanidine. Because of these results, pyridoxamine has been investigated for clinical utility in the treatment of diabetic nephropathy. Pyridoxamine also inhibits the formation of advanced lipoxidation endproducts during lipid peroxidation reactions by reaction with dicarbonyl intermediates.
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Most recently the fourteenth Congress of the International Association of Pancreatology developed the International Consensus Diagnostic Criteria (ICDC) for AIP. The ICDC emphasizes five cardinal features of AIP which includes the imaging appearance of pancreatic parenchyma and the pancreatic duct, serum IgG4 level, other organ involvement with IgG4-related disease, pancreatic histology and response to steroid therapy. In 2002, the Japanese Pancreas Society proposed the following diagnostic criteria for autoimmune pancreatitis: ::I. Pancreatic imaging studies show diffuse narrowing of the main pancreatic duct with irregular wall (more than 1/3 of length of the entire pancreas). ::II.
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It is important to note that DAD can occur in settings other than ARDS and that ARDS can occur with histology other than DAD. That being said, the histologic finding of DAD is often associated with the clinical syndrome ARDS but it can also be seen in conditions such as acute interstitial pneumonia (essentially ARDS but without a known inciting cause), acute exacerbation of idiopathic pulmonary fibrosis, and primary graft dysfunction after lung transplant. The most common causes of ARDS are pneumonia, non-pulmonary sepsis, and aspiration. To reiterate, the hallmark of DAD is hyaline membrane formation.
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In February 2004, the U.S. Food and Drug Administration (FDA) approved pemetrexed for treatment of malignant pleural mesothelioma, a type of tumor of the mesothelium, the thin layer of tissue that covers many of the internal organs, in combination with cisplatin for patients whose disease is either unresectable or who are not otherwise candidates for curative surgery.National Cancer Institute: FDA Approval for Pemetrexed Disodium In September 2008, the FDA granted approval as a first- line treatment, in combination with cisplatin, against locally advanced and metastatic non-small cell lung cancer (NSCLC) in patients with non-squamous histology.
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Microscopically, the tumor cells recapitulate embryonic sensory retina or nonpigmented ciliary epithelium. The chalky grayish-white particles within the tumor mass correspond to foci of cartilage on histology; the semi-translucent membrane covering the lens in some tumors corresponds to spreading neoplastic cells. Tumor cells form a characteristic diktyomatous pattern, with folded cords and sheets resembling a fisherman's net. In early development of the retina, the medullary epithelial cells acquire polarity, such that a basement membrane associated with the vitreous forms the internal limiting membrane on one side, while terminal bars form the outer limiting membrane on the other side.
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The narrow surgical margin used (smaller than the standard of care of 5 mm), combined with the limitation of the standard bread loafing technique of fixed tissue histology - result in a high "false negative" error rate, and frequent recurrences. Margin controlled (peripheral margins) is necessary to eliminate the false negative errors. If breadloafing is utilized, distances from sections should approach 0.1 mm to assure that the method approaches complete margin control. Where the lesion is on the face and either large or 5mm margins are possible, a skin flap or skin graft may be indicated/required.
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Upon the death of Professor S. E. Stratingh, he was appointed in his place at the university of Groningen. He took up this appointment on September 12, 1844 with an inaugural lecture entitled de veteris medicorum interpretis munere a medicis non recusando. He lectured on a wide variety of topics in medicine, due to the lack of a sufficient number of professors, a situation which, as Ermerins wrote to a good friend, "benefits neither professors nor students". Beginning in 1852, however, he limited himself to general pathology, pathological anatomy and histology, and clinical courses in the Academic hospital.
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In it, Mayzel discusses Cohnheim's claims that during inflammation, leukocytes exit blood vessels and take part in the formation of pus. After receiving a diploma cum eximia laude, Mayzel took up a position of a lab assistant in Hoyer's Histology and Embryology faculty, instructing students in microscope usage, and conducting his own research. While observing epithelium regeneration, he noticed that nuclei of some of the newly formed cells feature unknown to him grains and fibers. He then, in 1874, informed the Warsaw Medical Association about his research so as to be credited in case an important discovery is made.
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Eva Fischer was born on 22 January 1925 in Budapest, Hungary, to a well-to-do Jewish family. She attended private school, with an interest in sports, theater, and science (inspired by the life and work of Marie Curie). Her career choices were constrained by the political situation, with worsening anti-semitism and persecution when Hungary was occupied by Germany after she finished secondary school. Fischer attended medical school at the University of Budapest, and in 1944/45 she and several members of her family survived by hiding at the Histology Institute of the University of Budapest.
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For microanatomy, known as histology, a similar standard exists in Terminologia Histologica, and for embryology, the study of development, a standard exists in Terminologia Embryologica. These standards specify generally accepted names that can be used to refer to histological and embryological structures in journal articles, textbooks, and other areas. As of September 2016, two sections of the Terminologia Anatomica, including central nervous system and peripheral nervous system, were merged to form the Terminologia Neuroanatomica. Recently, the Terminologia Anatomica has been perceived with a considerable criticism regarding its content including coverage, grammar and spelling mistakes, inconsistencies, and errors.
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The study of microscopic anatomy (or histology) can be aided by practical experience examining histological preparations (or slides) under a microscope. Human anatomy, physiology and biochemistry are complementary basic medical sciences, which are generally taught to medical students in their first year at medical school. Human anatomy can be taught regionally or systemically; that is, respectively, studying anatomy by bodily regions such as the head and chest, or studying by specific systems, such as the nervous or respiratory systems. The major anatomy textbook, Gray's Anatomy, has been reorganized from a systems format to a regional format, in line with modern teaching methods.
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The calculation presented by De Ricqlès in 2003 of a growth phase of less than 20 weeks was based on the assumption that bone diameters grew by 10 µm per day, which is subjective. Rather, histology reveals the presence of different tissue types in the bone that grew at different rates, as well as pauses in growth as indicated by the lines of arrested growth. Thus, growth periods must have been longer than in modern birds and likely took several years, as is true for the modern kiwi. The observed size distribution can, therefore, be feasibly explained by assuming a dinosaurian-style growth.
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Soft and pliable waxes, like beeswax, may be preferred for such sculpture, but "investment casting waxes," often paraffin-based, are expressly formulated for the purpose. In a histology or pathology laboratory, paraffin wax is used to impregnate tissue prior to sectioning thin samples of tissue. Water is removed from the tissue through ascending strengths of alcohol (75% to absolute) and the tissue is cleared in an organic solvent such as xylene. The tissue is then placed in paraffin wax for a number of hours and then set in a mold with wax to cool and solidify; sections are then cut on a microtome.
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In 1942 Ellen Illich and her three children—Ivan, Alexander, and Michael—left Vienna, Austria for Florence Italy, escaping the Nazi persecution of Jews. He finished high school in Florence, and then went on to study histology and crystallography at the local University of Florence. Hoping to return to Austria following World War II, Illich enrolled in a doctorate in medieval history at the University of Salzburg with the hope of gaining legal residency as he was undocumented. He wrote a dissertation focusing on the historian Arnold J. Toynbee, a subject to which he would return in his later years.
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Eosin Y Eosin B Eosin is the name of several fluorescent acidic compounds which bind to and form salts with basic, or eosinophilic, compounds like proteins containing amino acid residues such as arginine and lysine, and stains them dark red or pink as a result of the actions of bromine on fluorescein. In addition to staining proteins in the cytoplasm, it can be used to stain collagen and muscle fibers for examination under the microscope. Structures that stain readily with eosin are termed eosinophilic. In the field of histology, Eosin Y is the form of eosin used most often as a histologic stain.
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There are actually two very closely related compounds commonly referred to as eosin. Most often used is in histology is Eosin Y (also known as eosin Y ws, eosin yellowish, Acid Red 87, C.I. 45380, bromoeosine, bromofluoresceic acid, D&C; Red No. 22); it has a very slightly yellowish cast. The other eosin compound is eosin B (eosin bluish, Acid Red 91, C.I. 45400, Saffrosine, Eosin Scarlet, or imperial red); it has a very faint bluish cast. The two dyes are interchangeable, and the use of one or the other is a matter of preference and tradition.
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In 2020, the Australian Research Council funded her Future Fellowship project "Illuminating behavioural and environmental influences on human development". Smith works broadly in the area of human evolutionary biology. Her research focuses on dental development and growth using histology, elemental chemistry, and advanced imaging techniques, and how dental tissues can be used to resolve taxonomic, phylogenetic, and developmental questions about great apes and humans. She works primarily on tooth microstructure, including the use of juvenile dentition for determining age at death, and how dental development correlates with aspects of an individual's life history, growth and reproduction.
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Histology of the thymus showing the cortex and medulla Minute structure of thymus. The ability of T cells to recognize foreign antigens is mediated by the T cell receptor (TCR), which is a surface protein able to recognize short protein sequences (peptides) that are presented on MHC. The purpose of thymocyte development is to produce mature T cells with a diverse array of functional T cell receptors, through the process of TCR gene rearrangement. Unlike most genes, which have a stable sequence in each cell which expresses them, the T cell receptor is made up of a series of alternative gene fragments.
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Unlike the other subtypes of Castleman disease, UCD and iMCD, which can present with a spectrum of features on microscopic analysis (histology) of tissue biopsied from an enlarged lymph node, only a plasmablastic pattern of histologic features has been described in HHV-8-associated MCD. Plasmablastic features are similar to the plasmacytic features seen in iMCD and UCD, with both demonstrating increased plasma cells in interfollicular spaces. Plasmablastic features are differentiated from plasmacytic features by increased numbers of plasmablasts in follicular mantle zones. Staining with latency-associated nuclear antigen (LANA-1), a marker for HHV-8 infection, is typically positive.
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Anatomical Sciences Education is a peer-reviewed journal that provides an international forum for the exchange of ideas, opinions, innovations and research on topics related to education in the anatomical sciences of gross anatomy, embryology, histology, and neurosciences at all levels of anatomical sciences education including, undergraduate, graduate, post-graduate, allied health, medical (both allopathic and osteopathic), and dental. It is the official publication of the American Association of Anatomists. According to the Journal Citation Reports, the journal has a 2019 impact factor of 3.759, ranking it 3rd out of 41 journals in the category "Education, Scientific Disciplines".
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The first year of the four year curriculum is composed of courses designed to provide students with a mastery of the normal structure and function of the human body. Basic science faculty are from both the college itself and Case Western Reserve University. In order to achieve this, didactic and hands on laboratory courses are combined to give students a solid foundation in fields such as biochemistry, histology, gross anatomy, neurobiology and physiology. Coursework during the second year focuses more on both variations and abnormalities that affect the organ systems of the human body, and ways to recognize and treat such pathology.
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The histology of EST is variable, but usually includes malignant endodermal cells. These cells secrete alpha-fetoprotein (AFP), which can be detected in tumor tissue, serum, cerebrospinal fluid, urine and, in the rare case of fetal EST, in amniotic fluid. When there is incongruence between biopsy and AFP test results for EST, the result indicating presence of EST dictates treatment. This is because EST often occurs as small "malignant foci" within a larger tumor, usually teratoma, and biopsy is a sampling method; biopsy of the tumor may reveal only teratoma, whereas elevated AFP reveals that EST is also present.
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In 1846 his collection of two thousand five hundred preparations was purchased by the college, and he was directed to prepare a descriptive illustrated catalogue of the whole histological collection belonging to the college, of which they constituted the chief part. In 1852 the title of his demonstratorship was changed to that of professor of histology; and on Owen's obtaining permission to reside at Richmond, Quekett was appointed resident conservator, finally succeeding Owen as conservator in 1856. His health, however, soon failed, and he died at Pangbourne, Berkshire, whither he had gone for the benefit of his health, on 20 Aug. 1861.
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Lydia and Anna Gurwitsch Gurwitsch was Professor of Histology and Embryology at Moscow University from 1924 to 1929 but fell afoul of the communist party and was forced to relinquish the chair. He then directed a laboratory at the Institute of Experimental Medicine in Leningrad from 1930 until 1945, though he was forced to evacuate during World War 2. In 1941 he was awarded a Stalin Prize for his mitogenetic radiation work since it had apparently led to a cheap and simple way of diagnosing cancer. He was director of the Institute of Experimental Biology in Leningrad from 1945 to 1948.
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He was the Chair of Georgetown University's Department of Biology from 1963–1990, where he initiated the Department’s graduate program and senior-thesis requirement and increased the size of its faculty. Under his chairmanship, the Department of Biology welcomed female professors including Rita R. Colwell, Ellen J. Henderson, and Diane Wallace Taylor. The Department annually awards the Chapman Medal to senior undergraduates for outstanding research projects. George Chapman taught cytology and histology and electron microscopy to several thousand pre-dental, premedical, and other students and about 250 medical students and mentored about 24 Ph.D. theses and nine M.S. theses.
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The body consists of many different types of tissue, defined as cells that act with a specialised function. The study of tissues is called histology and often occurs with a microscope. The body consists of four main types of tissues – lining cells (epithelia), connective tissue, nerve tissue and muscle tissue. Cells that lie on surfaces exposed to the outside world or gastrointestinal tract (epithelia) or internal cavities (endothelium) come in numerous shapes and forms – from single layers of flat cells, to cells with small beating hair-like cilia in the lungs, to column-like cells that line the stomach.
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The focus of the research undertaken by Smith's research involves investigating the pathological mechanism(s) underlying selective neuronal death in neurodegenerative diseases such as Alzheimer's disease. Further this research involves a variety of techniques including histology, state of the art molecular and cell biology and cellular and animal models of disease that are directed toward diagnostic, mechanistic, and therapeutic strategies. Current projects are directed towards 1) fundamental metabolic alterations; 2) homeostatic dysregulation of transition metals; 3) signal transduction alterations; and 4) inappropriate re-entry into the cell cycle. Smith collaborated with and co-authored works with, amongst others, Drs.
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Monospecific bonebeds suggest it was gregarious, and that this behavior gave Aniksosaurus a selective advantage over competitors in its paleoenvironment. The hypothesis suggesting gregarious (social) behavior is supported by the taphonomic association of individuals from the Bajo Barreal Formation and evidence garnered from analysis of its bone histology. The authors of this study, Ibiricu, Martínez, Casal and Cerda (2013) noted that this particular assemblage is only the second known body fossil association of small, coelurosaurian theropods discovered in South America. The theropod taxa have been interpreted as gregarious are Coelophysis bauri,Colbert EH (1989) The Triassic dinosaur Coelophysis.
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Rozella Pearl Beverly Blood was an only child, born 18 May 1911 in Wichita, Kansas, to Charles Gillman Blood and Sarah Dorothy 'Dollie' Sherman. She died in Boulder, Colorado on 15 December 1987. Rozella Blood enrolled in Wichita High School in 1929 and then became a student at the institution then-called the University of Wichita, earning a B.A. in 1932 and an M.S. in entomology in 1933. She went on to attend the University of Kansas Medical School as a graduate student and assistant instructor in anatomy, neurology and histology, also working as a staff artist, from 1933 to 1937.
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Recently, significant enhancement of fluorescence quantum yield of NIAD-4 was exploited to super-resolution fluorescence imaging of amyloid fibrils and oligomers. To avoid nonspecific staining, other histology stains, such as the hematoxylin and eosin stain, are used to quench the dyes' activity in other places such as the nucleus, where the dye might bind. Modern antibody technology and immunohistochemistry has made specific staining easier, but often this can cause trouble because epitopes can be concealed in the amyloid fold; in general, an amyloid protein structure is a different conformation from the one that the antibody recognizes.
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GCA is considered a medical emergency due to the potential of irreversible vision loss. Corticosteroids, typically high-dose prednisone (1 mg/kg/day), should be started as soon as the diagnosis is suspected (even before the diagnosis is confirmed by biopsy) to prevent irreversible blindness secondary to ophthalmic artery occlusion. Steroids do not prevent the diagnosis from later being confirmed by biopsy, although certain changes in the histology may be observed towards the end of the first week of treatment and are more difficult to identify after a couple of months. The dose of corticosteroids is generally slowly tapered over 12–18 months.
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In civilian life, Ambuhl was a histology technician at LabCorp in Herndon, Virginia. Including Delayed Entry time, Ambuhl served in the United States Army Reserve for two years and nine months. On February 21, 2003, Ambuhl was activated for service in the Iraq War. In a stipulation made during court- martial proceedings, Ambuhl wrote that she "received Geneva Convention and UCMJ training during an approximately 60–90 minute block of instruction in basic training, but cannot remember any specifics of those classes." Ambuhl was originally assigned to the 352nd Military Police Company, but was involuntarily transferred to the 372nd Military Police Company.
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In infants, fibrosarcoma (often termed congenital infantile fibrosarcoma) is usually congenital. Infants presenting with this fibrosarcoma usually do so in the first two years of their life. Cytogenetically, congenital infantile fibrosarcoma is characterized by the majority of cases having a translocation between chromosomes 12 and 15 (notated as t(12;15)(p13;q25)) that results in formation of the fusion gene, ETV6-NTRK3, plus individual cases exhibiting trisomy for chromosomes 8, 11, 17, or 20. The histology, association with the ETV6-NRTK3 fusion gene as well as certain chromosome trisomies, and the distribution of markers for cell type (i.e.
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After the rickettsia bacteria infects humans through a tick bite, it invades endothelial cells in the circulatory system (veins, arteries, capillaries). The body then releases chemicals that cause inflammation, resulting in the characteristic symptoms like headache and fever. The hallmark of all rickettsial diseases is a histology (cellular) finding called lymphohistiocytic vasculitis that involves immune cell deposition into the endothelial cells that make up vessels. This occurs secondary to the chemicals mentioned above, as well as damage from the infection, and involves signals to immune cells (T cells and macrophages) to come to the site of the infection.
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In 1893, Gage and John Henry Comstock founded the Comstock Publishing Company in order to make textbooks on microscopy, histology, and entomology available at a reasonable price to students and to publish the works of Anna Botsford Comstock on nature study. In 1931, Gage gave the company to Cornell University as a gift. Gage, along with Luzerne Corville and the architect, William H. Miller, designed Stimson Hall, which housed the Cornell Medical College. In 1915, Gage and his son started a memorial fund for Susanna Phelps Gage that was used to build a room in Clara Dickson Hall, the new dormatory for women.
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He worked for two years as graduate fellow in Clark University, Massachusetts, and became assistant professor of biology at the University of Texas at Austin, where after two years he was dismissed for libeling a member of the board of regents. He was made full professor at the University of Cincinnati in 1894 and remained there six years. From 1900 to 1910 he was the J. Pierpont Morgan Professor of Natural History in Trinity College, Connecticut. He then moved to University of Southern California where he was associate professor of biology (1911–1912), and Professor of Embryology and Histology (1912–1913).
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In 1941, she was appointed as temporary part-time Assistant Histologist to the Laboratory at the Royal College of Physicians of Edinburgh. From 1960, she moved to work at the Royal College of Surgeons of Edinburgh. In addition to performing the diagnostic histology she undertook a research work on the material in the Museum and donated to the College a large quantity of histological material and specimens, including whole sections of breast and other organs, some specially mounted for demonstration purposes. Several of these are still on display in the museum and a reference library which is publicly available.
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The diagnosis of H. cinaedei infection is made difficult by the fastidiousness of this organism: in culture, it grows very slowly and requires high humidity and microaerobic conditions. Furthermore, the bacterium, while being able to be cultured from blood specimens, is far harder to culture from tissue lesions such as those in the skin. Consequently, the diagnosis of H. cinaedie infection has been heavily based on: patient clinical presentations; histology of lesions including special staining for the bacterium; and analyses of tissue specimens by DNA sequencing and species-specific polymerase chain reactions to identify nucleotide gene sequences specific to the bacterium.
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Frederik Jacobus Johannes Buytendijk (1887–1974) was a Dutch anthropologist, biologist and psychologist. Frederik Jacobus Johannes Buytendijk (Breda, April 29, 1887 - Nijmegen, October 21, 1974) was a Dutch physician, psychologist and author. He graduated as a physician, was a lecturer in biology and general physiology at the VU University Amsterdam and received a chair in physiology there in 1919. In 1924 he became professor of physiology and histology in Groningen. From 1946 until his retirement in 1957, he was an extraordinary professor in Nijmegen and professor of psychology in Utrecht, although he had never studied psychology.
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In 1944, he joined the allied expeditionary force in the invasion of the continent with the British Liberation Army serving in field hospitals in Belgium and the Netherlands. Dr. Harold Taylor has pointed out that it was at this time that Joe's interest in fundamental biology became evident. Dr. Taylor happened to follow after McManus in three army hospitals, and in each he found that McManus had left a legacy: the best trained histology technicians Dr. Taylor had ever encountered. They had been painstakingly taught to use the McManus Periodic acid-Schiff stain to study normal kidneys, which led to his unique contributions on the nature of the juxtaglomerular complex.
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Scanning probe microscopy involves the interaction of a scanning probe with the surface of the object of interest. The development of microscopy revolutionized biology, gave rise to the field of histology and so remains an essential technique in the life and physical sciences. X-ray microscopy is three-dimensional and non-destructive, allowing for repeated imaging of the same sample for in situ or 4D studies, and providing the ability to "see inside" the sample being studied before sacrificing it to higher resolution techniques. A 3D X-ray microscope uses the technique of computed tomography (microCT), rotating the sample 360 degrees and reconstructing the images.
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In 1872 he was appointed Lecturer in Anatomy in Queen's College, and at the time of the establishment of the Royal College of Physicians and Surgeons of Canada in affiliation with Queen's University, he was appointed Professor of Anatomy. In 1883 he was President of the Canadian Medical Association, and was an Alderman from 1863 to 1873 and Mayor of Kingston from 1874 to 1875. He later became a Professor of Surgery and Histology, and was a trustee of the Kingston Hospital and a member of the Ontario Medical Association. He ran unsuccessfully for the House of Commons of Canada in the 1882 election for Kingston.
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In the same year he was appointed demonstrator, and later, lecturer, in the subjects of zoology, comparative anatomy, and histology at the university of Sydney. He was much interested in the fauna of the New South Wales coast, and especially in the Crustacea, Annelida and Bryozoa, but also did other work covering a wide field. When the Challis professorship of biology was founded in 1889, Haswell was given the position and held it until its division in 1913. In 1893 he published in the Macleay Memorial Volume "A Monograph of the Temnocephaleae", a group which retained his interest for the remainder of his life.
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He was Assistant Demonstrator in Histology from 1884–89, then House Surgeon at Guy's Hospital, London from 1889-95. From 1895-96 he worked at the Hygiene Institute, Vienna where he was associated with Professor Max von Gruber in the discovery of agglutination of bacteria. In 1897 he developed an agglutination reaction for diagnosis of typhoid fever, which then was called the Grubler-Durham reaction, subsequently known as the Widal reaction; and also created "Durham tubes" for measuring the amount of gas produced in the bacterial colonies, which are still used universally in microbiology laboratories.As expedições da Liverpool School of Tropical Medicine e a Amazônia Brasileira.
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This series of advancements in her professorship was almost unheard of for women during Hibbard's time; the standard progression of women professors was a drawn-out process, and female professors were commonly made to either wait for the completion an installed interval of time determined by international guidelines before rising in rank or remain at their current rank. Her steady elevation in the zoology department was therefore unorthodox in her day and age. Hibbard's research conducted while at Oberlin concentrated on a variety of fields, including cytology, histology, and marine biology. Her histological studies pinpointed research concerning organs and tissues of several marine invertebrates, including limpets, earthworms, silkworms, and squid.
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In protein engineering, flow cytometry is used in conjunction with yeast display and bacterial display to identify cell surface- displayed protein variants with desired properties. The main advantages of flow cytometry over histology and IHC is the possibility to precisely measure the quantities of antigens and the possibility to stain each cell with multiple antibodies-fluorophores, in current laboratories around 10 antibodies can be bound to each cell. This is much less than mass cytometer where up to 40 can be currently measured, but at a higher price and a slower pace. Flow cytometry protocols used for research often needs validation because of the risk of antibody binding to Fc receptors.
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Left to right: denticles of Paralogania (?), Shielia taiti, Lanarkia horrida The bony scales of the thelodont group, as the most abundant form of fossil, are also the best understood – and thus most useful. The scales were formed and shed throughout the organisms' lifetimes, and quickly separated after their death. Bone – being one of the most resistant materials to the process of fossilisation – often preserves internal detail, which allows the histology and growth of the scales to be studied in detail. The scales consist of a non-growing "crown" composed of dentine, with a sometimes-ornamented enameloid upper surface and an aspidine (acellular bony tissue) base.
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In 1947, Dr Simon Sevitt set up a pathology department that covered bacteriology, haematology, biochemistry, histology, and morbid anatomy. Though his best known work was in venous thrombosis and pulmonary embolism, fat embolism, and the healing of fractures, he was to become an "outstanding pathologist, particularly in accident surgery". His controversial 1959 paper on thromboembolism after fracture of the hip in old people written in conjunction with Gallagher, which found that fatal pulmonary embolism might occur 30 days or more after surgery for hip fracture triggered work by other researchers and revolutionised the profession's attitude to preventing, diagnosing, and treating the condition. Dr Sevitt died in September 1988.
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He earned the critics' attention in the 1890s as a short story writer with a socialist and pacifist message, but only returned to fiction writing briefly, in the 1930s. An award-winning ichthyologist, Bujor was hired by the University of Iași, where he taught for 41 years, and throughout the period worked on documenting the Black Sea fauna, and made discoveries concerning the environment of Techirghiol Lake. He inaugurated the Romanian study of animal morphology, while also contributing to histology, embryology, and parasitology, and gave popular lectures on evolution and physical culture. Bujor rallied with the Poporanist movement, infiltrating the National Liberal Party from the left.
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In the past, medulloblastoma was classified using histology, but recent integrated genomic studies have revealed that medulloblastoma is composed of four distinct molecular and clinical variants termed WNT/β-catenin, Sonic Hedgehog, Group 3, and Group 4. Of these subgroups, WNT patients have an excellent prognosis and group 3 patients have a poor prognosis. Also, a subgroup-specific alternative splicing further confirms the existence of distinct subgroups and highlights the transcriptional heterogeneity between subgroups. Amplification of the Sonic Hedgehog pathway is the best characterized subgroup, with 25% of human tumors having mutations in Patched, Sufu (Suppressor of Fused Homolog), Smoothened, or other genes in this pathway.
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In September 1877, she was engaged as instructor in microscopic botany, and placed in charge of a botanical laboratory, which position she held for twelve years. One of the leading features of that laboratory was the amount of original work accomplished in structural botany by both teacher and pupils. On July 10, 1878, in Saginaw City, Michigan, she married Charles Henry Stowell, M.D., professor of physiology and histology in the same university. In 1881, she co-founded the medical journal, The Microscope, and served as its editor through 1897, publishing it in Ann Arbor, Michigan, Detroit, Michigan, and Washington D.C. In 1882, she published a work entitled Microscopical Diagnosis (Detroit).
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The first English text appeared in 1960, and from that point onward English articles were frequently included. With the expanding field of pathology, it was decided in 1968 to divide the journal into two sections, namely part A dedicated to Pathologische Anatomie und Histologie and part B for Zellpathologie, later changed into Pathological Anatomy and Histology and Cell Pathology respectively, as the publication became more internationally oriented. Its entire publication language became English by the late 1970s, and the long German name of the journal itself was deleted. In 1994 the sister journals part A and B were merged with a new subtitle An International Journal of Pathology.
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RCTC offers certificates, diplomas, associate of arts degrees, associate of fine arts degrees, associate of science degrees, and associate of applied science degrees. Because of the proximity of Mayo Clinic to RCTC, many of the programs offered are medically focused, and a few are awarded in conjunction with the Mayo School of Health Sciences, including Cardiovascular Invasive Specialist, Clinical Research Coordinator, Clinical Neurophysiology Technology, and Histology. RCTC also offers a number of continuing education and custom training program for individuals, business, and industry. Services include designing specific training for organizations, allied health continuing education, entrepreneurship offerings, small business development, and continuing education of general interest.
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Histology suggests that UMZC T836 may have reached skeletal maturity, as closely spaced growth marks are present in the lamellar-zonal bone of the outer part of the cortex. It is not known why the outermost thin layer of bone directly below the external bone surface does not show these marks, interpreted as an outer circumferential layer. If they are truly absent, not simply obscured, this would argue against such interpretation indicating that this individual had a prolonged period in life of several years as an adult in which it experienced unfavorable growth conditions, like nutritional shortage, drought or disease, leading to limited growth. Ezcurra et al.
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Holocrine secretion Holocrine is a term used to classify the mode of secretion in exocrine glands in the study of histology. Holocrine secretions are produced in the cytoplasm of the cell and released by the rupture of the plasma membrane, which destroys the cell and results in the secretion of the product into the lumen. Holocrine gland secretion is the most damaging (to the cell itself and not to the host which begot the cell) type of secretion, with merocrine secretion being the least damaging and apocrine secretion falling in between. Examples of holocrine glands include the sebaceous glands of the skin and the meibomian glands of the eyelid.
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In the fields of histology, pathology, and cell biology, fixation is the preservation of biological tissues from decay due to autolysis or putrefaction. It terminates any ongoing biochemical reactions and may also increase the treated tissues' mechanical strength or stability. Tissue fixation is a critical step in the preparation of histological sections, its broad objective being to preserve cells and tissue components and to do this in such a way as to allow for the preparation of thin, stained sections. This allows the investigation of the tissues' structure, which is determined by the shapes and sizes of such macromolecules (in and around cells) as proteins and nucleic acids.
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IPASS (IRESSA Pan-Asia Study) was a randomized, large-scale, double-blinded study which compared gefitinib vs. carboplatin/ paclitaxel as a first-line treatment in advanced NSCLC. IPASS studied 1,217 patients with confirmed adenocarcinoma histology who were former or never smokers. A pre-planned sub-group analyses showed that progression-free survival (PFS) was significantly longer for gefitinib than chemotherapy in patients with EGFR mutation positive tumours (HR 0.48, 95 per cent CI 0.36 to 0.64, p less than 0.0001), and significantly longer for chemotherapy than gefitinib in patients with EGFR mutation negative tumours (HR 2.85, 95 per cent CI 2.05 to 3.98, p less than 0.0001).
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Artery wall structure, showing intimal layer Immunological (innate and adaptive) and nonimmunological factors contribute to the complex pathogenesis of CAV. In those nontransplanted people who develop coronary artery disease due to atherosclerosis, progression of disease is slow, histological changes are confined mainly to the main coronary arteries and arterial dilatation is observed as a form of compensatory remodelling. However, in CAV, histology specimens typically show concentric thickening of the intimal layer of the main coronary arteries on the surface of the heart and in intramyocardial arteries which can become obliterated within a few years. There is smooth muscle cell migration, foamy macrophages and lymphocytic infiltrates.
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Candidates for the TQ were first required to pass a preliminary entrance examination or show evidence of an approved university degree. The former School of Medicine of the Edinburgh Royal Colleges They were then required to complete a curriculum as follows:In addition to the above, many candidates took voluntary additional courses which included sanitary science, histology, botany, psychiatry, dermatology, ophthalmic surgery, diseases of the ear, nose and throat and therapeutics. These regulations were rigorously enforced and exceptions were rarely granted. Doctors who had qualified elsewhere in the world, often with years of experience were still required to complete the clinical elements and in many cases the basic science elements.
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He was sent to Moscow to work as a doctor at the Lefortovo Military Hospital, and continued to study and worked at the Moscow University Chair of Histology. In Moscow, Dr. Marić became acquainted with biologist and histologist Professor Vladimir Porfirevich Karpov (1870-1943). Karpov became the dean of a Medical School at the University of Ekaterinoslav (now Dnjepropetrovsk) and Dr. Marić was invited to work at the Dnipropetrovsk Medical Institute in the Dnieper, Ukraine. On his arrival in the Dnieper, Dr. Miloš Marić married Karpov's daughter Marija Vasiljevna Karpova, although his first marriage was officially over when he was declared missing and his first wife Martha was "widowed".
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He entered the University of Michigan in 1869 and was graduated Bachelor of Arts in 1873. His further preparation for professional life included work in Cryptogamic and Physiological Botany at Harvard University, in Anatomy at Cornell, in Histology at the University of Pennsylvania, and in Plant Physiology at the University of Jena. The years from 1892 to 1894 he spent at the University of Leipzig, where he received the degree of Doctor of Philosophy at the conclusion of his studies. The years from 1873 to 1876 were spent in public school work, first as principal of the Battle Creek High School, and later of the Flint High School.
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There are several different ways for aquatic tetrapod to counteract their positive buoyancy caused by their lungs: pachyostosis, osteosclerosis, pachyosteosclerosis, and calcified cartilage of bone. The ultimate goal of these processes are to increase density for different parts of the body to offset the buoyancy, in order to live in an aquatic/semi-aquatic environment. Bone histology of Pistosaurus longaevus studied by Paleontologist Krahl showed that the medullary region of humeri was filled, and it contained calcified cartilage incorporated into endoseal bone. According to Krahl, the small region of medullary of humeri is results from a suppressed perimedullary resorption activity, which is associated with osteosclerosis.
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Advances in the fields of histology and cytology began in the late 19th century along with advances in surgical techniques allowing for the painless and safe removal of biopsy specimens. The invention of the electron microscope brought a great advance in resolution power and allowed research into the ultrastructure of cells and the organelles and other structures within them. About the same time, in the 1950s, the use of X-ray diffraction for studying the crystal structures of proteins, nucleic acids and other biological molecules gave rise to a new field of molecular anatomy. Equally important advances have occurred in non-invasive techniques for examining the interior structures of the body.
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Arnold was the author of 120 articles in the fields of histology and pathological anatomy.Julius Arnold @ Who Named It With Austrian pathologist, Hans Chiari, his name is lent to a condition known as Arnold–Chiari malformation, a disorder that takes place when the cerebellar tonsils and the medulla oblongata protrude through the foramen magnum into the spinal canal, without displacing the lower brain stem.Arnold-Chiari malformation @ Who Named It Arnold described his pathological findings associated with the disorder from an infant who died shortly after delivery. He published his account of the disorder in an 1894 paper titled "Myelocyste, Transposition von Gewebskeimen und Sympodie".
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Rare cases of DLBCL are associated with the presence of the bacterium, Helicobacter pylori, in the neoplastic B-cells. While the histology of Helicobactor pylori-associated diffuse large B-cell lymphoma (H. pylori+ DLBCL) is typical of DLBCL, the disease is sometimes a progression of mantle cell lymphoma, is often restricted to the stomach, is less aggressive that most DLBCL cases, and may respond to a drug regimen consisting of antibiotics and proton pump inhibitors directed at killing the bacterium. Perhaps because of these features of the disease, H. pylori+ DLBCL has not been classified as a DLBCL by the World Health Organization, 2016.
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A graph showing the hypothesized growth curves (body mass versus age) of four tyrannosaurids, with Albertosaurus drawn in red Most age categories of Albertosaurus are represented in the fossil record. Using bone histology, the age of an individual animal at the time of death can often be determined, allowing growth rates to be estimated and compared with other species. The youngest known Albertosaurus is a two-year-old discovered in the Dry Island bonebed, which would have weighed about 50 kilograms (110 lb) and measured slightly more than in length. The specimen from the same quarry is the oldest and largest known, at 28 years of age.
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The French anthropologist Robert Gessain interested himself in what he called the tache pigmentaire congenitale or coloured birthmark, publishing multiple papers in the Journal de la Société des Américanistes, an academic journal covering the cultural anthropology of the Americas. Gessain spent time with the Huehuetla Tepehua people in Hidalgo, Mexico, and wrote in 1947 about the spot's "location, shape, colour, histology, chemistry, genetic transmission, and racial distribution". He had previously spent several winters in Greenland, and wrote an overview in 1953 of what was known about the spot. He hypothesised that the age at which it faded in various populations might prove to be a distinguishing characteristic of those groups.
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Pangolin skeletons at the Museum of Osteology (2009) Schematic drawing of pangolin scale histology The physical appearance of a pangolin is marked by large hardened overlapping plate-like scales, which are soft on newborn pangolins, but harden as the animal matures. They are made of keratin, the same material from which human fingernails and tetrapod claws are made, and are structurally and compositionally very different from the scales of reptiles. The pangolin's scaled body is comparable in appearance to a pine cone. It can curl up into a ball when threatened, with its overlapping scales acting as armor, while it protects its face by tucking it under its tail.
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A phase III clinical trial was carried out on 493 histology or cytology- confirmed stage IIIB and IV NSCLC patients with a life expectancy >3 months. Patients were treated with Endostar (rh-endostatin, YH-16), a recombinant endostatin product, in combination with vinorelbine and cisplatin (a standard chemotherapeutic regimen). The addition of Endostar to the standard chemotherapeutic regimen in these advanced NSCLC patients resulted in significant and clinically meaningful improvement in response rate, median time to progression, and clinical benefit rate compared with the chemotherapeutic regimen alone.Results of phase III trial of rh-endostatin (YH-16) in advanced non-small cell lung cancer (NSCLC) patients (Y.
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Mainly as a result of reforms following the Flexner Report of 1910 medical education in established medical schools in the US has generally not included alternative medicine as a teaching topic. Typically, their teaching is based on current practice and scientific knowledge about: anatomy, physiology, histology, embryology, neuroanatomy, pathology, pharmacology, microbiology and immunology. Medical schools' teaching includes such topics as doctor-patient communication, ethics, the art of medicine, and engaging in complex clinical reasoning (medical decision-making). Writing in 2002, Snyderman and Weil remarked that by the early twentieth century the Flexner model had helped to create the 20th-century academic health center, in which education, research, and practice were inseparable.
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Its juvenile status is reflected by the small size of the type specimen which indicates a total body length of about two feet. The authors, Philip J. Currie and Peng, did not find any autapomorphies of Saurornithoides, but based on the then current knowledge of anatomy and genera, the assignment was reasonable. In 2011, Linhevenator was described, and IVPP V 10597 was shown to have many similarities to this new taxon, possibly being a juvenile. However, a 2012 study of the histology and osteology of IVPP V 10597 determined that it was a new taxon related to Linhevenator, and it was named Philovenator curriei by Xu Xing e.
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After the 1917 revolution Gurwitsch fell upon hard times and accepted the chair of Histology at Taurida University, the chief seat of learning of the Crimean Peninsula, where he spent seven happy years. Here in 1923 he first observed biophotons or ultra-weak biological photon emissions; weak electromagnetic waves which were detected in the ultra-violet range of the spectrum. Gurwitsch named the phenomenon mitogenetic radiation since he believed that this light radiation allowed the morphogenetic field to control embryonic development. His published observations, which related that cell-proliferation of an onion was accelerated by directing these rays down a tube, brought him great attention.
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GBM in the frontal right lobe as seen on CT scan Sagittal MRI with contrast of a glioblastoma WHO grade IV in a 15-year-old boy Glioblastoma (histology slide) Axial post-contrast T1 (top) and T2 (bottom) weighted MRI showing an IDH1 mutant frontal lobe glioblastoma with sparse enhancement despite large size. When viewed with MRI, glioblastomas often appear as ring-enhancing lesions. The appearance is not specific, however, as other lesions such as abscess, metastasis, tumefactive multiple sclerosis, and other entities may have a similar appearance. Definitive diagnosis of a suspected GBM on CT or MRI requires a stereotactic biopsy or a craniotomy with tumor resection and pathologic confirmation.
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This indicates a rate of growth that is 40% slower than that of comparably sized non-avian theropods, a finding that is supported by the unusual prominence of parallel-fibered bone which is known to be associated with relatively slow growth. However, individuals in this genus grew 40% faster than crocodylians. Lee and O'Connor noted that the evolution of slow growth gave this dinosaur the advantage of minimizing the nutritional investment allocated toward structural growth while living in a semiarid and seasonally stressful environment.Andrew H. Lee & Patrick M. O’Connor (2013) Bone histology confirms determinate growth and small body size in the noasaurid theropod Masiakasaurus knopfleri.
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When he returned to Quebec he began teaching at Laval in a variety of subjects including forensic medicine, inorganic chemistry, histology and toxicology. La Rue was a major contributor to the literary movement of 1860. He wrote extensively in the magazines and newspapers of his time, notably in the Courrier du Canada, L'Événement, Soirées Canadiennes, Foyer Canadien, and in La Ruche littéraire, where he signed his name Isidore de Méplats. One of his most remarkable studies is his work on Chansons populaires et historiques du Canada (1863), which he published: Le Voyage sentimental sur la rue Saint-Jean; départ en 1860, retour en 1880 (1879); le Voyage autour de l'Isle d'Orléans.
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Although an 18th-century doctor would examine a diseased organ as would a 19th-century doctor, but, because of their different medical cultures, each doctor would reach a different conclusion about the cause and treatment of the disease. Despite their perceptual differences of diagnosis, each medical report would be “true”, because each doctor diagnosed according to the way of thinking (the episteme) that considered their the respective, organised medical knowledge to be factual. Hence, despite their medical researches having occurred thirty years apart, the father of anatomical pathology, Giovanni Battista Morgagni (1682–1771), and the father of histology, Xavier Bichat (1771–1802), did not practise the same human anatomy.
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As well as histology demonstration slides, the box contains slides which may be related to original breakthroughs such as cortical localization in the brain; slides from contemporaries such as Angelo Ruffini and Gustav Fritsch; and slides from colleagues at Oxford such as John Burdon-Sanderson – the first Waynflete Chair of Physiology – and Derek Denny-Brown, who worked with Sherrington at Oxford (1924–1928)). Sherrington's teachings at Oxford were interrupted by World War I. When the war started, it left his classes with only nine students. During the war, he laboured at a shell factory to support the war and to study fatigue in general, but specifically industrial fatigue.
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A semiaquatic lifestyle has been proposed for many spinosaurids, on account of their unusual anatomical traits and bone histology. Cristatusauruss teeth would have likely been used for piercing and gripping prey items, rather than slicing flesh, as indicated by their subcircular cross section and reduced serrations. Its teeth, combined with the sinusoidal (wave-like) curvature of the jaws, would have performed as tan efficient trap for fish. The retracted nostrils would have allowed it to submerge its snout further underwater than most theropods, while still being able to breathe; and the bony secondary palate is theorized to have reinforced the skull against bending stresses when feeding.
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Baxter translated Rindfleisch's Pathological Histology for the New Sydenham Society; prepared the fourth edition of Garrod's Essentials of Materia Medica; and made some valuable experiments on "The Action of the Chinchona Alkaloids and their Congeners on Bacteria and Colourless Blood Corpuscles" described in the Practitioner (1873). He also drew up an able "Report on the Experimental Study of certain Disinfectants" printed in the Privy Council Reports (1875); and contributed a remarkable article to the British and Foreign Medico-Chirurgical Review in 1877 on the vaso-motor nervous system. His minor writings include a series of physiological notes which he contributed to the Academy for many years.
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Lower jaws at various growth stages It was identified that Europasaurus was a unique dwarf species, and not a juvenile of an existing taxon like Camarasaurus, by a histology analysis of multiple specimens of Europasaurus. The youngest specimen (DFMMh/FV 009) was shown by this analysis to lack signs of aging such as growth marks or laminar bone tissue, and is also the smallest specimen at in length. Such bone tissue is an indicator of rapid growth, so the specimen is probably a young juvenile. A larger specimen (DFMMh/FV 291.9) at shows large amounts of laminar tissue, with no growth marks present, so is likely a juvenile as well.
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In 1873, Gage entered Cornell University and graduated in 1877 with a B. S. in Natural History after writing a thesis on the life history of the Cayuga Lake Stargazer (Cottus). As an undergraduate, Gage worked in the Department of Anatomy with Burt Green Wilder teaching in the newly introduced biology courses. In the fall of 1877, Gage became an instructor of Comparative Anatomy and Microscopy. In 1881, Gage became an Assistant Professor of Physiology and Lecturer in Microscopical Technology. In 1889, Gage became an Associate Professor of Physiology and Lecturer on Microscopical Technology and in 1893, Gage became an Associate Professor of Anatomy, Histology, and Embryology.
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Most of the single calcified nodules were malignant. However, this did not include patients with ITNs and the sample is skewed towards malignancy. Another study evaluated the presence of ITNs on CT scans and found that 12 % of thyroid nodules were calcified, with no significant correlation between malignant or potentially malignant histology and punctate calcifications. As a result, some researchers believe that calcification per se is not a suspicious CT sign, and have suggested that calcified thyroid nodules on CT scans should be treated the same as non-calcified nodules. Fig. 1. An incidentally discovered colloid nodule with calcification, shown on CT scan of a 58-year-old female patient.
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Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as Berberis, such as Berberis vulgaris (barberry), Berberis aristata (tree turmeric), Mahonia aquifolium (Oregon grape), Hydrastis canadensis (goldenseal), Xanthorhiza simplicissima (yellowroot), Phellodendron amurense (Amur cork tree), Coptis chinensis (Chinese goldthread), Tinospora cordifolia, Argemone mexicana (prickly poppy), and Eschscholzia californica Californian poppy). Berberine is usually found in the roots, rhizomes, stems, and bark. Due to its yellow color, Berberis species were used to dye wool, leather, and wood. Under ultraviolet light, berberine shows a strong yellow fluorescence, making it useful in histology for staining heparin in mast cells.
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If he did much for these branches of science, he did still more for histology, the knowledge of the minute structure of the animal tissues. Among his earlier results was the demonstration in 1847 that smooth or unstriated muscle is made up of distinct units, of nucleated muscle cells. In this work, he followed in the footsteps of his master Henle. A few years before this, there was doubt whether arteries had muscle in their walls – in addition, no solid histological basis as yet existed for those views as to the action of the nervous system on the circulation, which were soon to be put forward, and which had such a great influence on the progress of physiology.
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Later, in 2017, another team re- evaluated the specimen, and determined through investigating the fossils at a microscopic level (in a process called histology) that this was correct, although they doubted the significance of some of the characters identified in the former study. Though the quality of bone preservation is generally poor, the holotype skeleton is estimated to be 60% complete. It consists of a left maxilla and dentary, parietal, various isolated skull elements, thirteen cervical vertebrae, six dorsal vertebrae, two sacral vertebrae, a series of 35 caudal vertebrae, a left scapula, lower portions of both humeri, most elements of the lower forelimbs, an ischium, left ilium, and most of the hindlimbs.
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Early in his career, Marinescu published a much needed atlas on the pathological histology of the nervous system with the bacteriologist Victor Babeş and the French pathologist Paul Oscar Blocq. His description with Blocq, of a case of Parkinsonian tremor due to tumour in the substantia nigra in 1893, was the basis for Édouard Brissaud's theory that Parkinsonism occurs as a consequence of damage to the substantia nigra. With Blocq he was the first to describe senile plaques and with Romanian neurologist Ion Minea he confirmed in 1913 Hideyo Noguchi's discovery of Treponema pallidum in the brain in patients with general paresis. His monumental work La Cellule Nerveuse, with a preface by Santiago Ramon y Cajal, appeared in 1909.
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He used a variety of anatomical and statistical arguments to defend his case, the methodology of which was fiercely debated among scientists. These debates sparked interest in new methods for ascertaining the palaeobiology of extinct animals, such as bone histology, which have been successfully applied to determining the growth-rates of many dinosaurs. Today, it is generally thought that many or perhaps all dinosaurs had higher metabolic rates than living reptiles, but also that the situation is more complex and varied than Bakker originally proposed. For example, while smaller dinosaurs may have been true endotherms, the larger forms could have been inertial homeotherms, or many dinosaurs could have had intermediate metabolic rates.
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Montessori moved forward with her intention to study medicine. She appealed to Guido Baccelli, the professor of clinical medicine at the University of Rome, but was strongly discouraged. In 1890, she enrolled in the University of Rome in a degree course in natural sciences, passing examinations in botany, zoology, experimental physics, histology, anatomy, and general and organic chemistry, and earning her diploma di licenza in 1892. This degree, along with additional studies in Italian and Latin, qualified her for entrance into the medical program at the University in 1893.Kramer 34–35; Trabalzini 9–10 She was met with hostility and harassment from some medical students and professors because of her gender.
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The Moscow Stomatological Institute (MSI) as a higher dental school was established under the Narkomzdrav's order dated June 9, 1935, as a subdivision within the SRISO's framework. Both institutions were housed in one building, sharing administration, finances and facilities. Thus, the MSI became the only institution in the Russian Soviet Federal Socialist Republic (RSFSR) that was to conduct scientific research in dentistry, translate the results obtained into everyday dental care practices and train dental professionals as well. Since 1935 a whole number of departments were being added to the institute those of normal anatomy, biology, general chemistry, histology, embryology, and, finally, in 1937 the departments of oral therapy, oral surgery and prosthodontics.
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Old building of the Pauls Stradiņš Clinical University Hospital On 2 February 1920, Swedish professor Gaston Bakman held the first lecture on human anatomy in the Theatrum Anatomicum Rigense (currently Anatomical Theatre in Riga). This lecture was the forebearer of higher education in medicine in Latvia. Professor Gaston Bakman believed that this was also the beginning of the Institute of Anatomy and Histology, as well as the Museum of Anatomy in Riga. After World War II, only two professors of medicine remained in Latvia, one of whom was Professor Pauls Stradiņš, who in a very short time as the Dean of the Faculty of Medicine managed to rebuild and renew the education and science of medicine from scratch.
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Microscope-based diagnostics are widely performed and served as a gold standard in histological analysis. However this procedure generally requires a series time-consuming lab-based procedures including fixation, paraffin embedment, sectioning, and staining to produce microscope slides with optically thin tissue slides (4-6 µm). While in developed regions histology is commonly used, people who live in areas with limited resources can hardly access it and consequently are in need for a low- cost, more efficient way to access pathological diagnosis Adeyi, O. A. Pathology services in developing countries—the West African experience. Arch. Pathol. Lab. Med. 135, 183–186 (2011) Benediktsson, H., Whitelaw, J. & Roy, I. Pathology services in developing countries: a challenge. Arch. Pathol. Lab. Med.
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Rees' career was at the Zoology Department of the University College of Wales, Aberystwyth, where she successively held positions of Assistant Lecturer (1930–7), Lecturer (1937–47), Senior Lecturer (1947–66), Reader (1966–71) and Professor (1971–3), becoming Professor Emeritus in semi-retirement in 1973. She was also Chairman of the School of Biological Studies (1972–3) and acting Head of Department (1948, 1969, 1970). During her time as a staff member at the University College of Wales at Abernathy Rees supervised 215 honours students and 25 post-graduate students. Her research was in the area of helminthology, focusing on systematics, comparative functional morphology, histology and life cycles of trematode and cestode parasites.
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In zoology the word "collocyte" applies to several different types of cell in very different taxa, and there are a few similar terms used confusingly or interchangeably, such as colloblast. Some of the terms refer to specialised subject matter, so from time to time variations and inconsistent definitions have been coined independently in niche disciplines. For example, glial cells sometimes are called "glue cells" but have little in common with other types of so-called glue cells. Apart from such difficulties, "glue cells" of various types commonly occur in taxa of animals that are practically unrelated to each other, and in such cases they are as a rule non-homologous and differ profoundly in their morphology, histology and function.
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The diagnosis of AGEP may be forthright in typical cases in which an individual: has taken a drug known to cause the disorder; develops multiple sterile pustules overlying large areas of red swollen skin starting a few days after initial drug intake; and has a histology of biopsied lesions that shows pustules just below the skin's Stratum corneum (outermost layer), apoptotic (i.e. necrotic) keratinocytes, spongiosis of the stratum spinosum, and infiltration of these tissues by neutrophils plus, in many but not all cases, eosinophils. Many cases of AGEP, however, present less clear cut clinical features of the disorder. AGEP must be differentiated from generalized pustular psoriasis (GPP) with which it shares many clinical and histological features.
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His contributions include the development of new methods for preserving anatomical specimens for teaching (using a mixture of glycerine and arsenic), introducing histology (rather than just gross anatomy) as a part of the training for surgeons, propagating the antiseptic methods of Lister and knee surgery, although his surgical practice was very broad. He wasn't a prolific author, but did write entries for Heath's Dictionary of Practical Surgery and as an Editor for Guy's Hospital Reports. For the Royal College of Surgeons he was Vice-president (1897-1900) then President (1901–1903). He was knighted in the 1902 Coronation Honours list, receiving the accolade from King Edward VII at Buckingham Palace on 24 October that year.
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Dakotaraptor might have used its arms to keep its balance while subduing prey; here Ornithomimus is the victim The keeled claw of the second toe, the "sickle claw", was used to bring down prey and had a more robust flexor tubercle than that of Utahraptor. To the contrary, the third foot claw was relatively smaller in size than with other dromaeosaurids and seems not to have had an important function in attacking prey animals. Two morphs, a robust and a gracile one, were present in the fossil material. A study of the bone histology showed that both morphs were adult, so the lighter build of some bones was not caused by a young age.
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It is possible that Gargantuavis lived mainly in an environment that was not compatible with fossilization, such as areas far from the rivers and floodplains, which represent most of the fossiliferous deposits in the late Campanian-early Maastrichtian of France and Spain. Bone histology showed that Gargantuavis had a rapid early growth followed by an extended period (of at least 10 years) of slow cyclical growth before to attain skeletal maturity. A similar pattern is known in extinct dinornithiformes and in the extant kiwi, which are also insular birds. The titanosaur Ampelosaurus, found together with Gargantuavis in the Bellevue site, shows also a reduction in its growth rate, possibly linked to some environmental pressure like periodic food shortages.
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Involved tissues usually include mucosa-associated lymphoid tissues and evidence a histology of lymphoplasmacytoid infiltrates accompanied by large numbers of plasma cells and small lymphocytes. The plasma cells therein express the monoclonal α chain and therefore are clonal in nature and the sole or contributing producer of the α chain myeloma protein. Some 57% to 66% of patients present with disseminated lymphoma, 17% to 36% of patients present with a localized lymphoma, and 9% to 17% of patients lack any evidence of a lymphoplasmacytic neoplasm. A majority of the latter patients have an autoimmune disease or a chronic infection which may be responsible for, or contribute to, production of the α heavy chain.
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He became Professor of Anatomy and Histology at the University College of Agriculture in Warsaw in 1935. In 1939, following the German and Soviet invasions of Poland, Kazimierz escaped arrest to Italy while his wife Maria Wodzicka, a skilled mountaineer, guided other refugees over the mountains across the southern border of Poland and then took the children with her to unite with as a family in Paris. The family then moved to England and then to New Zealand in 1941 as Consul-General for the London-based Polish government-in-exile. When the Soviets occupied Poland, the family estates were taken and his father, Count Wodzicki was deported to Siberia, where he died.
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In 1917, Greenfield took membership in the Royal College of Physicians, earned his MD with a gold medal from the University of Edinburgh in 1921, and was elected a fellow of the college in 1925. During his time at the National Hospital, Greenfield collaborated with Farquhar Buzzard on several publications, including research on von Economo’s encephalitis in 1919 and Pathology of the Nervous System in 1921. Late infantile metachromatic leukodystrophy is occasionally known by the eponym Greenfield's disease because of his work studying its pathophysiology and histology. Greenfield played an important role in defining neuropathology as a distinct discipline, including lecturing to the Royal College of physicians on 'the pathology of the neuron' in 1939.
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Mutu's 12-panel series Histology of the Different Classes of Uterine Tumors, made up of collaged digital prints, was exhibited in the Hudson Showroom. Her work is included in the collections of the Museum of Modern Art, New York; The Whitney Museum of American Art; The Studio Museum in Harlem; Museum of Contemporary Art, Chicago; the Museum of Contemporary Art, Los Angeles; the Nasher Museum of Art at Duke University; the Musée d'art contemporain de Montréal (Museum of Contemporary Art, Montréal); the Brooklyn Museum; and Tate Modern in London. She is represented by Barbara Gladstone in New York, Susanne Vielmetter Los Angeles Projects in Los Angeles, and Victoria Miro Gallery in London.
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Guillermo Jaim Etcheverry Guillermo Jaim Etcheverry (born December 31, 1942) is an Argentine physician, former rector of the Universidad de Buenos Aires (UBA). Jaim Etcheverry obtained his M.D. in 1965 and his Ph.D. in 1972, both at the School of Medicine of the University of Buenos Aires. Committed since his graduation to teaching and full-time research in the field of Neurobiology, he was Principal Investigator of the Argentinean National Council of Research (CONICET) until 2012 as well as full professor and director of the Department of Cell Biology and Histology of the School of Medicine of the University of Buenos Aires until 2008. During 1986-1990 he was Dean of that School of Medicine.
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3Scan CEO Todd Huffman originally worked as a neuroinformatics researcher at Texas A&M; in 2003 and first encountered the technology which became the core of 3Scan's microscopy services during this time. While the KESM was originally developed as a neuroimaging tool, 3Scan has taken the principles involved in this technology and expanded its use to create a novel type of histology and tissue imaging. The company has raised a total of $22 million through two rounds of equity funding from Lux Capital and Data Collective, joined by Dolby Family Ventures, OS Fund, Comet Labs, and Breakout Ventures. They have also raised $390,000 in non-dilutive grant money from institutions such as Breakout Labs and Start-Up Chile.
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During this time he published several articles relating to physiological chemistry and histology, but finally turned his especial attention to pathological anatomy. In 1867 there appeared in Virchow's "Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin" (xli) Cohnheim's essay, "Ueber Entzündung und Eiterung", which made his reputation as a pathologist. In it he proved that the emigration of the white blood- corpuscles is the origin of pus, a statement which produced a great revolution in pathology. In 1868 Cohnheim was appointed professor of pathological anatomy and general pathology in the University of Kiel; and four years later (1872) he went to the University of Breslau to fill a similar position.
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His interest in the area of crude drugs began when he realised that little was known about those imported into Britain. After years of research he acquired an extensive knowledge of the history of origin, morphology and histology of crude drugs where he was later appointed professor of material medica at the London Hospital. His book on Materia Medica was the first great English work on Pharmacology and he was foremost in putting the knowledge and use of drugs on a scientific footing. During one of his first lectures held at the School of Pharmacy he spoke about ‘material medica consisting of three parts: (1) pharmacognosy, pharmacology, pharmacopathia or the history of simple drugs; (2) pharmacy, and (3) pharmacodynamics.
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A liver sinusoid is a type of capillary known as a sinusoidal capillary, discontinuous capillary or sinusoid, that is similar to a fenestrated capillary, having discontinuous endothelium that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.SIU SOM Histology GI The liver sinusoid has a larger caliber than other types of capillaries and has a lining of specialised endothelial cells known as the liver sinusoidal endothelial cells (LSECs), and Kupffer cells. The cells are porous and have a scavenging function. The LSECs make up around half of the non-parenchymal cells in the liver and are flattened and fenestrated.
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Johan Bollin and Edward O. Wilson, 'Social insect histology from the 19th century: the magnificent pioneer sections of Charles Janet, (2008) Arthropod Structure and Development 37, 163–167 He also worked on plant biology and finally wrote a series of papers on evolution. He was a prolific inventor and designed much of his own equipment, including the formicarium, in which an ant colony is made visible by being formed between two panes of glass. In 1927 he turned his attention to the periodic table and wrote a series of six articles in French, which were privately printed and never widely circulated. His only article in English was poorly edited and gave a confused idea of his thinking.
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Other studies have all supported the view that growth to adult size was slow, as it is in living precocial birds (as opposed to altricial birds, which are known to reach adult size quickly). Studies of the rate of bone growth in a variety of enantiornitheans has shown that smaller species tended to grow faster than larger ones, the opposite of the pattern seen in more primitive species like Jeholornis and in non-avialan dinosaurs. Some analyses have interpreted the bone histology to indicate that enantiornitheans may not have had fully avian endothermy, instead having an intermediate metabolic rate. Evidence of colonial nesting has been found in enantiornitheans, in sediments from the Late Cretaceous (Maastrichtian) of Romania.
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Three years later he transferred to the Central Institute for Microbiology (Zentralinstitut für Molekularbiologie / ZIM), in the Berlin-Buch, becoming initially deputy director and then, in 1981, the director of the institute in succession to Friedrich Jung. From 1984 his ability to work began to be restricted by serious illness, and the directorship of the institute passed to the immunologist . Zschiesche nevertheless remained committed to his scientific research at the academy, working at the Centre for Vertebrate Research, headed up by Heinrich Dathe, where till the end of the 1980s he led a histology working group. In 1989 he also accepted an appointment as deputy chairman of the newly created Centre for Medical Research at the academy.
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Oscarella lobularis has been used as a model organism for the study of evolutionary biology and developmental biology, being particularly suitable because of its easy availability, its simple histology and cell composition, its robust epithelial structures and because it lacks a skeleton. Researchers have studied the different colour morphs of this sponge which sometimes grow alongside each other. There appears to be a cryptic complex and two species that had been synonymised in 1877 have been redescribed as O. lobularis (violet in colour) and O. tuberculata; these species can be distinguished from each other cytologically, and by the former having a soft consistency and the latter a cartilaginous consistency. Several other new species have been described, mostly from caves.
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He used a variety of anatomical and statistical arguments to defend his case, the methodology of which was fiercely debated among scientists. These debates sparked interest in new methods for ascertaining the palaeobiology of extinct animals, such as bone histology, which have been successfully applied to determining the growth-rates of many dinosaurs. Today, it is generally thought that many or perhaps all dinosaurs had higher metabolic rates than living reptiles, but also that the situation is more complex and varied than Bakker originally proposed. For example, while smaller dinosaurs may have been true endotherms, the larger forms could have been inertial homeotherms, or that many dinosaurs could have had intermediate metabolic rates.
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1: Total loss of attachment (clinical attachment loss, CAL) is the sum of 2: Gingival recession, and 3: Probing depth As the original sulcular depth increases and the apical migration of the junctional epithelium has simultaneously occurred, the pocket is now lined by pocket epithelium (PE) instead of junctional epithelium (JE).Antonio Nanci, Ten Cate's Oral Histology, Elsevier, 2007, page 383 To have a true periodontal pocket, a probing measurement of 4 mm or more must be clinically evidenced. In this state, much of the gingival fibers that initially attached the gingival tissue to the tooth have been irreversibly destroyed. The depth of the periodontal pockets must be recorded in the patient record for proper monitoring of periodontal disease.
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Alexander Rollett in his study Alexander Rollett (14 July 1834 – 1 October 1903) was an Austrian physiologist and histologist born in Baden bei Wien, Niederösterreich. He studied with Ernst Wilhelm von Brücke (1819–1892) in Vienna, and in 1863 became a professor of physiology and histology at the University in Graz. He was a prime factor in making Graz an international center for physiological training and education. Between 1872 and 1903 he was rector of the university four times, and from 1893 was president of the Styrian Medical Association. He was a member of the Austrian Academy of Sciences (1864), a corresponding member of the Societas Medicorum Svecana (1882) and the Royal Bavarian Academy of Sciences (1892).
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In 1922, after receiving his baccalaureate, he enrolled in the University of Pavia, Italy, as a foreign student. From 1923 to 1925, Feider attended Histology and Pathology classes of the famous professor Camillo Golgi, the scientist-physician who discovered the Golgi apparatus, the Golgi tendon organ and the Golgi tendon reflex. Unfortunately, the student Feider was feeding himself poorly, and in 1925, after three years of starvation, he contracted pulmonary tuberculosis, which was still ravaging lives at the time. Forced to leave his studies in Italy, he returned to Romania, and was admitted to the Tuberculosis Sanatorium of Bârnova, close to Iași, where he strictly followed the rudimentary anti-tuberculous of treatment of that time.
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Blood is circulated around the body through blood vessels by the pumping action of the heart. In animals with lungs, arterial blood carries oxygen from inhaled air to the tissues of the body, and venous blood carries carbon dioxide, a waste product of metabolism produced by cells, from the tissues to the lungs to be exhaled. Medical terms related to blood often begin with hemo- or hemato- (also spelled haemo- and haemato-) from the Greek word (haima) for "blood". In terms of anatomy and histology, blood is considered a specialized form of connective tissue, given its origin in the bones and the presence of potential molecular fibers in the form of fibrinogen.
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Woodward was admitted as the first woman Member of the Royal College of Physicians in July 1909. In 1905, she is listed in the Medical Directory as house physician at the Royal Free Hospital, while living at 12 West Cromwell Road, London. In 1910, she is listed in the Medical Directory as medical registrar, Royal Free Hospital, having previously been its museum curator, demonstrator in morbid histology, clinical assistant, and assistant clinical pathologist. She also worked in this period as clinical assistant then senior clinical assistant in the Children’s Department at the New Hospital for Women, assistant schools medical officer for London County Council and medical examiner for Kensington High School and Notting Hill High School.
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In 1982 he held the post of principal academic surgeon at Tygerberg Hospital (Parow, South Africa). He was also engaged in doctoral, preclinical and laboratory research at the Nuffield Department of Surgery, John Radcliffe Hospital under the headmanship of Sir Professor Peter Morris and focused on pancreas transplantation for diabetes mellitus as well as the development of chemical immune suppressants such as cyclosporine. He has held faculty based, academic teaching and research professorship appointments in Surgery (ad hominem) as well as Anatomy and Histology at the University of Stellenbosch and focused on medical, para medical and post graduate surgeon education by application of applied digital imaging, theoretical and cadaveric teaching.du Toit Donald Prof.
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HHV-8-associated MCD is diagnosed based on patient history, physical exam, laboratory testing, radiologic imaging, and microscopic analysis (histology) of biopsied tissue from an enlarged lymph node. Formal criteria for the diagnosis of HHV-8-associated MCD have not been published; however, diagnosis requires enlargement of lymph nodes in multiple lymph node regions (typically confirmed with radiologic imaging), histologic changes consistent with HHV-8-associated MCD on biopsy of an enlarged lymph node, and confirmation of HHV-8 infection by LANA-1 lymph node staining or peripheral blood polymerase chain reaction for HHV-8. HIV testing is useful for management, but a positive result is not necessary for to diagnose HHV-8-associated MCD.
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A weakness with standard surgical excision is a reported higher recurrence rate of basal-cell cancers of the face, especially around the eyelids, nose, and facial structures. There is no clear approach for treating basal-cell carcinoma around the eye. A diagram on page 38 of the National Comprehensive Cancer Network publication demonstrate the area of high risk of recurrence as being most of the face with the exception of the central cheek and upper forehead. For ill-defined or recurrent basal-cell cancer on the face after previous surgery, special surgical margin controlled processing (CCPDMA – complete circumferential peripheral and deep margin assessment) using frozen section histology (Mohs surgery is one of the methods) should be considered.
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The 1891 founding professors included Robert Allardice in mathematics, Douglas Houghton Campbell in botany, Charles Henry Gilbert in zoology, George Elliott Howard in history, Oliver Peebles Jenkins in physiology and histology, Charles David Marx in civil engineering, Fernando Sanford in physics, and John Maxson Stillman in chemistry. The total initial teaching staff numbered about 35 including instructors and lecturers. For the second (1892–93) school year, Jordan added 29 additional professors including Frank Angell (psychology), Leander M. Hoskins (mechanical engineering), William Henry Hudson (English), Walter Miller (classics), George C. Price (zoology), and Arly B. Show (history). Most of these two founding groups of professors remained at Stanford until their retirement and were referred to as the "Old Guard".
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Currently there are no clinically established laboratory investigations available to predict prognosis or therapeutic response. Tumors in children who develop OMS tend to be more mature, showing favorable histology and absence of n-myc oncogene amplification than similar tumors in children without symptoms of OMS. Involvement of local lymph nodes is common, but these children rarely have distant metastases and their prognosis, in terms of direct morbidity and mortality effects from the tumor, is excellent. The three-year survival rate for children with non-metastatic neuroblastoma and OMS was 100% according to Children’s Cancer Group data (gathered from 675 patients diagnosed between 1980 and 1994); three-year survival in comparable patients with OMS was 77%.
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At the University of Melbourne from 1992 - 2009 Sandra taught undergraduate courses in neuroscience, histology, developmental neuroscience and cell biology and carried a full teaching load with convening responsibilities. Sandra has had extensive experience on committees at the university, faculty and departmental levels, serving on academic boards, equity and staff development committees and various selection committees for student and career interruption scholarships, as well as leadership programs for women. Sandra has been actively involved in mentoring young scientists, and has participated in women's mentoring programs, leadership courses and has given invited presentations to talk about women in research. Her laboratory has collaborated with research groups at Monash University, INSERM U676 Paris, France and Washington, Harvard and Oxford Universities.
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She remained on the faculty of George Washington University, where in 1909 she was Instructor of Histology and Embryology. From 1916 through 1920 she served as Anatomist at the Army Medical Museum, now the National Museum of Health and Medicine, on the Walter Reed Army Medical Center post in Washington, D.C. Her records at the museum, consisting of correspondence, notes, reports, logbooks, and other research materials, state that her research centered on identifying mosquitoes, including a project working with specimens sent in from military posts that resulted in the production of a Museum film, "Mosquito Eradication," in 1918. During 1920, she became the museum's Chief Entomologist, a position she held until her death.
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In the histology of skeletal muscle, a triad is the structure formed by a T tubule with a sarcoplasmic reticulum (SR) known as the terminal cisterna on either side. Each skeletal muscle fiber has many thousands of triads, visible in muscle fibers that have been sectioned longitudinally. (This property holds because T tubules run perpendicular to the longitudinal axis of the muscle fiber.) In mammals, triads are typically located at the A-I junction; that is, the junction between the A and I bands of the sarcomere, which is the smallest unit of a muscle fiber. Triads form the anatomical basis of excitation- contraction coupling, whereby a stimulus excites the muscle and causes it to contract.
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PTMs were first observed in 1901, when Claudius Regaud made a detailed study of the histology and physiology of the seminiferous tubules in rats. He described the PTMs as a single layer of flattened cells, which enclose the seminiferous tubules, and called them ‘’modified connective tissue cells’’. In 1958, Yves Clermont made a further investigation of the cells by electron microscopy. He found that these cells have a cytological resemblance to smooth muscle cells – they contain actin filaments, have invaginations at the cell surface and their organelles are located in the centre of the cell. He also suggested that these cells are responsible for the tubular contraction and referred to them as ‘’interlamellar cells’’.
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