How to use orthomyxovirus in a sentence? Find typical usage patterns (collocations)/phrases/context for "orthomyxovirus" and check conjugation/comparative form for "orthomyxovirus". Mastering all the usages of "orthomyxovirus" from sentence examples published by news publications.
SHRV induced interferon (IFN) and orthomyxovirus resistance (Mx) gene expression in zebrafish at levels dependent on route of inoculation and fish age.
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Orthomyxovirus viral glycoproteins then travel to the cell membrane where they form a spherical bud to transport negative-stranded vRNA out of the host cell. After the new viral material leaves the host cell, the host cell is terminated.
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Influenza A virus subtype H7N7 (A/H7N7) is a subtype of Influenza A virus, a genus of Orthomyxovirus, the viruses responsible for influenza. Highly pathogenic strains (HPAI) and low pathogenic strains (LPAI) exist. H7N7 can infect humans, birds, pigs, seals, and horses in the wild; and has infected mice in laboratory studies. This unusual zoonotic potential represents a pandemic threat.
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The Orthomyxovirus family consists of 5 genera: Influenzavirus A, Influenzavirus B, Influenzavirus C, Isavirus, and Thogotovirus. The "RNA viruses" include the "negative-sense ssRNA viruses" which include the Family "Orthomyxoviridae" which contains five genera, classified by variations in nucleoprotein (NP and M) antigens. One of these is the Genus "Influenzavirus A" which consists of a single species called "Influenza A virus"; one of its subtypes is H5N1. H5N1 (like the other avian flu viruses) has strains called "highly pathogenic" (HP) and "low-pathogenic" (LP).
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Viral replication and transcription of associated virus orthomyxovirus There is limited information of the replication cycle specific to TiLV, but it is known to be in the family Orthomyxoviridae due to its single-stranded negative-sense RNA genome. Typical Orthomyxoviridae carry several surface glycoproteins that recognize and bind to sialic acid receptors on the target cell membrane. The target cell transports the virus into the cell by receptor-mediated endocytosis, initiating endosome acidification. This acidification results in a conformational change of the viral glycoprotein, initiating membrane fusion of the viral envelope and endosomal membrane.
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Through in situ hybridization, it is found that transcription of the TiLV viral genome occurs in the nucleus, this is common among all Orthomyxoviridae. The nucleocapsid of an orthomyxovirus is transported to the nucleus where it is transcribed by viral enzymes resulting in the production of viral mRNA. Cap sequences are taken from the host cell mRNA during transcription and bound to viral mRNA, this allows the viral mRNA to exit the nucleus and return to the cytoplasm of the host cell where it will by recognized and translated into proteins by host cell ribosomes. The 5' and 3' noncoding termini of TiLV include 13 similar nucleotides, this enables base pairing and replication, transcription, and packaging of viral RNA as a result of the formation of secondary structures.
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