Firing and vesication have not been productive of beneficial results.
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The vesication produced is the test of the presence of cantharides.
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Later, vesication of a liberal area surrounding the trochanter major is indicated.
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The application is to be renewed night and morning, until vesication is produced.
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I simply evacuated the fluid of the vesication and left the part exposed to dry.
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Absorption by the skin is most vigorous when the cuticle is removed by vesication, or blistering.
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Hypophosphites in assimilable form may be beneficial, and vesication of the patellar region contributes to recovery.
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Still more remarkable are the cases of vesication produced in hypnotized subjects by means of suggestion.
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Later, vesication of the whole pericarpal region is done and the subject allowed exercise at will.
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In the course of ten days or two weeks, if the acute painful condition has entirely subsided, vesication is indicated.
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Their alkylation may cause changes in the cellular architecture and, in direct line with that, be determinative for the onset of vesication.
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The effects of PARP on the mode of cell death in different skin cell types may determine the severity of vesication in vivo, and thus have implications for the design of PARP inhibitors to reduce sulfur mustard pathology.
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Early symptoms include a cough and fever. When skin or inhalation exposure occur, ricin can cause an allergy to develop. This is indicated by edema of the eyes and lips; asthma; bronchial irritation; dry, sore throat; congestion; skin redness (erythema); skin blisters (vesication); wheezing; itchy, watery eyes; chest tightness; and skin irritation. An antidote has been developed by the UK military, although it has not yet been tested on humans.
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Reported side effects are: neurological reactions (e.g., headache, dizziness, drowsiness, disorientation, hallucinations, and convulsions), nausea, vomiting, diarrhea, constipation, mucositis, anorexia, stomatitis, bone marrow toxicity (dose-limiting toxicity; may take 7–21 days to recover after the drug has been discontinued), megaloblastic anemia, thrombocytopenia, bleeding, hemorrhage, gastrointestinal ulceration and perforation, immunosuppression, leukopenia, alopecia (hair loss), skin rashes (e.g., maculopapular rash), erythema, pruritus, vesication or irritation of the skin and mucous membranes, pulmonary edema, abnormal liver enzymes, creatinine and blood urea nitrogen. Due to its negative effect on the bone marrow, regular monitoring of the full blood count is vital, as well as early response to possible infections.
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