How to use unsequestered in a sentence? Find typical usage patterns (collocations)/phrases/context for "unsequestered" and check conjugation/comparative form for "unsequestered". Mastering all the usages of "unsequestered" from sentence examples published by news publications.
The alpha-3 subunit (COL4A3) of collagen IV is thought to be the antigen implicated in Goodpasture syndrome, wherein the immune system attacks the basement membranes of the glomeruli and the alveoli upon the antigenic site on the alpha-3 subunit becomes unsequestered due to environmental exposures. Goodpasture syndrome presents with nephritic syndrome and hemoptysis. Microscopic evaluation of biopsied renal tissue will reveal linear deposits of Immunoglobulin G by immunofluorescence. This is classically in young adult males.
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A significant portion of the toxicity of copper comes from its ability to accept and donate single electrons as it changes oxidation state. This catalyzes the production of very reactive radical ions, such as hydroxyl radical in a manner similar to Fenton chemistry. This catalytic activity of copper is used by the enzymes with which it is associated, thus is only toxic when unsequestered and unmediated. This increase in unmediated reactive radicals is generally termed oxidative stress, and is an active area of research in a variety of diseases where copper may play an important but more subtle role than in acute toxicity.
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Copper toxicity can occur from excessive supplement use, eating acid foods cooked in uncoated copper cookware, exposure to excess copper in drinking water, or as the result of an inherited metabolic disorder in the case of Wilson's disease. A significant portion of the toxicity of copper comes from its ability to accept and donate single electrons as it changes oxidation state. This catalyzes the production of very reactive radical ions, such as hydroxyl radical in a manner similar to Fenton chemistry. This catalytic activity of copper is used by the enzymes with which it is associated, thus is only toxic when unsequestered and unmediated.
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" The jury pool was then polled through a "challenge for cause" procedure to determine if a potential juror had been influenced by the media coverage prior to the publication bans taking effect. When the bans were lifted, a large media presence attended and reported on the trial, including American television programs Dateline NBC and 48 Hours. Following his first-degree murder conviction, Twitchell used the extensive media coverage of his case as grounds for an appeal. He argued in his notice of appeal that "the media attention surrounding my case was so extensive, so blatant and so overtly sensationalized that it is unreasonable to expect any unsequestered jury to have remained uninfluenced by it, regardless of judges' instructions in the charge.
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