Health care providers should monitor patients for sepsis when transfusing platelets, the CDC advised.
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Recent research has shown that transfusing this mixture rather than individual components improves survival rates.
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But this result suggests that for practical purposes, transfusing young blood shouldn't be a top research priority.
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Peter Thiel has some wild ideas, but transfusing teen blood into his own body might not be his bag.
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The harm of transfusing blood not formally tested for Zika must be weighed against the benefits, depending on local circumstances.
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Karmazin says that his company was merely conducting a clinical trial, transfusing plasma from donors under twenty-five years old.
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In the 1800s, doctors knew that transfusing blood between individuals could cause red blood cells to clump — a phenomenon called agglutination.
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"It bleeds out of the judicial branch power to interpret the law, transfusing that power into the executive branch," he said.
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He'd read the literature on self-experimentation, and tallied the results: eight deaths (including that of the blood-transfusing Alexander Bogdanov), and ten Nobel Prizes.
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In experiments unthinkable today, Rosenberg had tried just that, transfusing the cured man's blood into the veins of a terminal cancer patient in the next bed.
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But when stories started coming out that tech billionaire Peter Thiel was interested in transfusing teen blood into his own body, it sent Silicon Valley into a fever dream.
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A newer development is blood doping—transfusing blood or taking a synthetic version of erythropoietin (EPO), a hormone produced in the kidneys, to increase levels of red blood cells.
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He credits the heart specialist, a key member of the team, for giving the right medication and transfusing the right amount of fluid, allowing the surgeons to continue their work.
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Partridge and her co-authors also detail different techniques that have been tested on mice to reduce the effects of aging, including transfusing blood from human umbilical cords into older mice.
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Blood-stem-cell transplantation involves using drugs (backed up, in Mr Brown's case, by radiotherapy) to kill a patient's natural blood-producing tissue, the bone marrow, and then transfusing in new stem cells from a donor.
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The drones, manufactured by California robotics company Zipline, will begin delivering blood to 21 transfusing facilities in the western part of Rwanda, where poor roads and healthcare infrastructure have often made it difficult to reach patients in need.
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Therapies that aim to treat disease by altering a patient's genetics have made strides over the past year, but typically those therapies have relied on making any genetic changes outside of the human body, then transfusing the corrected cells into the patient.
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Pew asked about three techniques that might emerge in the future but that are not even close to ready now: using gene editing to protect babies from disease, implanting chips in the brain to improve people's ability to think, and transfusing synthetic blood that would enhance performance by increasing speed, strength and endurance.
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Plastic bags for storing and transfusing blood. Lancet, v.1, 1958, pp. 294‐296. Intestinal pseudo‐obstruction.
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In adults with upper gastrointestinal bleeding transfusing at a higher threshold caused harm (increased risk of death and bleeding).
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Woodlands Medical Centre is beginning a randomised controlled trial to look into the benefits of transfusing leukoreduced whole blood for the ICCU patients.
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Involves transfusing red blood cells without removing any of the patient’s blood. It is used when the patient's hemoglobin is much lower than normal, for example an aplastic crisis.
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Transfusing platelets is the only known treatment for abciximab- induced thrombocytopenia, but this therapy may have limited effectiveness because the drug may bind and inhibit the receptors on the newly transfused platelets.
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Issues in transfusing preterm infants in the NICU. Journal of Perinatal and Neonatal Nursing 18(2), 170-182. Retrieved December 4, 2007, from EbscoHost Research Databases. It is likely that only a carefully selected subpopulation of infants may benefit from its use.
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Transfusion associated circulatory overload is prevented by avoiding unnecessary transfusions, closely monitoring patients receiving transfusions, transfusing smaller volumes of blood at a slower rate, and considering the use of diuretics. A pre-transfusion TACO checklist can be used to assess patients' risk of developing TACO.
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The increasingly recognized problem of inadequate efficacy of transfusion is also raising the profile of RBC viability and quality. Notably, U.S. hospitals spend more on dealing with the consequences of transfusion-related complications than on the combined costs of buying, testing/treating, and transfusing their blood.
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The primary method to treat transfusion-dependent anemia is by transfusing packed red blood cells. Transfusion is also one of the treatment strategies for beta-thalassemia patients and patients with myelodysplastic syndrome (MDS). Although transfusion of red blood cells cannot correct the underlying problems, it can improve anemia conditions.
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This explains why his uncle Henry didn't recognize him; he appeared more mature to Henry. Polgas suggests that they try transfusing Dado with his blood to counteract this condition; Dado agrees. As they banter, the courier for the mushrooms arrives. It's no other than Renate Domingo, alias Atong Damuho, Polgas' mortal enemy.
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In general, by transfusing healthy stem cells to the recipient's bloodstream to reform a healthy immune system, allogeneic HSCTs appear to improve chances for cure or long-term remission once the immediate transplant-related complications are resolved.Venkat, Chaya (July 19, 2005). "The Only Real Cure Out There, for Now " . CLL Topics, Inc.
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Cardiopulmonary bypass surgery can result in destruction of a large proportion of the patient's platelets and may render the remaining viable platelets to be dysfunctional. The indications for transfusion in such patients is controversial. General guidelines recommend not transfusing patients prophylactically but only when they are bleeding excessively, while also giving desmopressin.
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There is less evidence for specific transfusion thresholds in children compared to adults. There has only been one randomized trial assessing different thresholds in children, and this showed no difference between a restrictive or liberal transfusion strategy. This trial used similar thresholds to the adult studies, and transfusing when the hemoglobin is less than 70g/L is also recommended in children.
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Blood transfusions in those without symptoms is not recommended until the hemoglobin is below 60 to 80 g/L (6 to 8 g/dL). In those with coronary artery disease who are not actively bleeding transfusions are only recommended when the hemoglobin is below 70 to 80g/L (7 to 8 g/dL). Transfusing earlier does not improve survival. Transfusions otherwise should only be undertaken in cases of cardiovascular instability.
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Young blood transfusion refers to transfusing blood specifically from a young person into an older one with the intention of creating a health benefit. The scientific community currently views the practice as essentially pseudoscientific, with comparisons to snake oil. There are also concerns of harm. The U.S. Food and Drug Administration, in 2019, cautioned "consumers against receiving young donor plasma infusions" stating that they are an "unproven treatment".
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Georgia re- instituted the death penalty. He advocated harvesting the organs from inmates after the death penalty was carried out for transplant into sick patients, but failed to gain the cooperation of prison officials. As a pathologist at Pontiac General Hospital, Kevorkian experimented with transfusing blood from the recently deceased into live patients. He drew blood from corpses recently brought into the hospital and transferred it successfully into the bodies of hospital staff members.
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The Ultimate Marvel imprint version of Henry "Hank" Pym is portrayed as a brilliant but mentally fragile scientist. He takes Prozac to battle his mental instability and depressive episodes. He gains his Giant-Man abilities after transfusing the blood of his mutant wife Janet Pym. The character is expelled from the Ultimates after his abusive behavior ends his marriage and his Giant-Man serum is used by S.H.I.E.L.D. to make an entire Giant-Men team.
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This refers to transfusing a single unit or bag of red blood cells to a person who is not bleeding and haemodynamically stable followed by an assessment to see if further transfusion is required. The benefits of single unit transfusion include reduced exposure to blood products. Each unit transfused increases the associated risks of transfusion such as infection, transfusion associated circulatory overload and other side effects. Transfusion of a single unit also encourages less wastage of red blood cells.
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House decides to buy time by transfusing the newborn with the mother's blood. The baby improves but the team is unsure why. The mother has melanoma, a mole under her finger nail, which has been passed to the baby. She is unusually healthy for someone with late-stage melanoma, and the team discover it is because she also has lung cancer which is causing antibodies to be created which are fighting off the melanoma and giving her blood an added factor which helped the baby.
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Depletion of inorganic phosphate within the cell is required for activation of the Pho regulon in most prokaryotes. In the most commonly studied bacterium, E. coli, seven total proteins are used to detect intracellular levels of inorganic phosphate along with transfusing that signal appropriately. Of the seven proteins, one is a metal binding protein (PhoU) and four are Phosphate- specific transporters (Pst S, Pst C, Pst A, and Pst B). The transcriptional response regulator PhoR activates PhoB when it senses low intracellular inorganic phosphate levels.
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During his PhD research, Dr. Fakhri carried out a series of experiments to determine an effective method to treat cancer with immunotherapy. He published several papers on his results, demonstrating the successful treatment of cancer in animals using macrophages and antibodies. In order to apply his findings to human subjects, he examined human peritoneal macrophages for the possibility of transfusing them between individuals. He tested for the presence of HLA D antigens, which are responsible for the rejection of foreign macrophages, on the surfaces of macrophages.
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Joseph is able to pass it on to Jotaro, but is fatally wounded by DIO who uses his blood to increase the duration of his ability. Jotaro then fights DIO alone, slowly discovering that he shares DIO's time-stopping ability, due to Star Platinum having similar abilities and stats to The World. The battle ends with Jotaro defeating DIO using the ability, transfusing DIO's blood back into Joseph, before destroying the vampire for good. Jotaro and Joseph then bid Polnareff farewell before returning to Japan, as Holly has made a full recovery.
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To the outside public he was endeared as a statesman who could do or suffer "nothing base", and who had the rare power of transfusing his own indomitable energy and courage into all who served under him. "A spirited foreign policy" has always been popular in England, and Pitt was the most popular of English ministers, because he was the most successful exponent of such a policy. In domestic affairs his influence was small and almost entirely indirect. He himself confessed his unfitness for dealing with questions of finance.
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Evidence indicates that a great number of the patients who are being transfused today may not be seeing many tangible benefits from it, as the transfused blood fails to achieve its primary goals – prevention of ischemia and improving the clinical outcomes. The challenge lies in identifying those patients who are at risk of complications of severe anemia (ischemia) and transfusing them, without exposing other patients to unwarranted risks of inappropriate transfusions. Better transfusion practice should not be viewed as an option, but a necessity to ensure clinicians are doing good and not doing harm to their patients.
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Arnault Tzanck (1886–1954) was a French physician and a pioneer of blood transfusion. During the First World War, he was a doctor in the military ambulance where he realized the vital role of the blood transfusions. Arnault Tzanck's name is attached to an apparatus he invented that was widely used for transfusing blood in France between the wars, as well as a simple test he devised using the microscopic analysis of scrapings from skin cancer lesions, different ganglia, and some forms of dermatitis especially pemphigus. The Tzanck smear is still widely used as a test for herpes, among other diseases.
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Twins were subjected to weekly examinations and measurements of their physical attributes by Mengele or one of his assistants. The experiments he performed on twins included unnecessary amputation of limbs, intentionally infecting one twin with typhus or some other disease, and transfusing the blood of one twin into the other. Many of the victims died while undergoing these procedures, and those who survived the experiments were sometimes killed and their bodies dissected once Mengele had no further use for them. Nyiszli recalled one occasion on which Mengele personally killed fourteen twins in one night by injecting their hearts with chloroform.
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These machines sometimes also carry a metal cage or basket which is used to hold human captives so the Martians can later revitalize themselves by fatally transfusing their captives' blood supplies by using pipettes. The height of the fighting machines is unclear; a newspaper article describes them to be more than tall. But they are also observed wading through relatively deep sea water. HMS Thunder Child, a Royal Navy torpedo ram, engages a trio of tripods that are pursuing a refugee flotilla heading to France from the southeast English coast; the Thunder Child is eventually destroyed by the Martian heat- ray, but not before taking out two fighting machines.
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Little about the Martians is definitive, the story being told by a first- person narrator. The Martians are described as octopus-like creatures: the "body" consisting of a disembodied head nearly across, having two eyes; a V-shaped, beak-like mouth; and two branches each of eight 'almost whip-like' tentacles, grouped around the mouth, referred to as the 'hands'. They reproduce asexually, by "budding" off from a parent. Internally, the Martians consist of a brain, lungs, heart, and blood vessels; they have no organs for digestion, and therefore sustain themselves on Earth by mechanically transfusing blood via pipettes from other animals, notably humans.
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Single unit transfusion refers to transfusing a single unit or bag of blood product to a person who is not bleeding and haemodynamically stable followed by an assessment to see if further transfusion is required.. The benefits of single unit transfusion include reduced exposure to blood products. Each unit transfused increases the associated risks of transfusion such as infection, transfusion associated circulatory overload and other side effects. Transfusion of a single unit also encourages less wastage of blood products and can be cost-effective. Single unit transfusion can be as part of an institutional or national guidelines and instituted with the help of a transfusion committee or transfusion practitioner.
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In the second season, forty-eight of the remaining detainees are captured and taken to Mount Weather by the Mountain Men. The Mountain Men are transfusing blood from imprisoned grounders as an anti-radiation treatment as their bodies have not adapted to deal with the remaining radiation on Earth. Medical tests of the forty-eight show their bone marrow will allow the Mountain Men to survive outside containment, so the Mountain Men begin taking the youths' bone marrow. Meanwhile, the inhabitants of the Ark have crash-landed various stations on Earth and begin an alliance with the grounders to save both their people, naming the main settlement at Alpha Station "Camp Jaha".
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Jehovah's Witnesses now corporate body under public law in Bavaria In the states of Baden-Württemberg,Baden-Württemberg refuses to grant status of corporate body under public law and Bremen,No recognition as corporate body under public law the group was denied the status in 2011. Due to their status of corporate body under public law (in some states), Jehovah's Witnesses in 2010 filed a complaint for broadcasting time at Germany's international broadcaster, Deutsche Welle. Jehovah's Witnesses file complaint for broadcasting time, Welt Online, 06.07.2010 Concerning the issue of blood transfusions, the Federal Constitutional Court has held that transfusing blood to an unconscious Jehovah's Witness violated the person's will, but did not constitute a battery.
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If the patient was receiving warfarin at the time when HIT is diagnosed, the activity of warfarin is reversed with vitamin K. Transfusing platelets is discouraged, as a theoretical risk indicates that this may worsen the risk of thrombosis; the platelet count is rarely low enough to be the principal cause of significant hemorrhage. Various nonheparin agents are used as alternatives to heparin therapy to provide anticoagulation in those with strongly suspected or proven HIT: danaparoid, fondaparinux, bivalirudin, and argatroban. Not all agents are available in all countries, and not all are approved for this specific use. For instance, argatroban is only recently licensed in the United Kingdom, and danaparoid is not available in the United States.
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In the worldwide Spanish flu pandemic of 1918, "Pharmacists tried everything they knew, everything they had ever heard of, from the ancient art of bleeding patients, to administering oxygen, to developing new vaccines and serums (chiefly against what we now call Hemophilus influenzae – a name derived from the fact that it was originally considered the etiological agent – and several types of pneumococci). Only one therapeutic measure, transfusing blood from recovered patients to new victims, showed any hint of success." In 1931, viral growth in embryonated hens' eggs was reported by Ernest William Goodpasture and colleagues at Vanderbilt University. The work was extended to growth of influenza virus by several workers, including Thomas Francis, Jonas Salk, Wilson Smith and Macfarlane Burnet, leading to the first experimental influenza vaccines.
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Clarinda is wooed by her uncle's best friend, the absurd orator Sir Formal Trifle, and Miranda by a gallant fool, Sir Samuel Hearty. To gain admittance to Sir Nicholas's house where they can see their beloveds, Bruce and Longvil feign an interest in Sir Nicholas's absurd experiments, which include learning to swim on dry land by imitating a frog, transfusing the blood of a sheep into a man (resulting in a sheep's tail growing out of the man's anus), and bottling air from various parts of the country to be stored in his cellar like wine. While they attempt to pay court to Miranda and Clarinda, Bruce and Longvil are in turn courted by Sir Nicholas's promiscuous wife, Lady Gimcrack, who also keeps a lover, Hazard, on the side. Sir Nicholas similarly keeps a lover by the name of Mrs.
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Donald T. Ridley, "Jehovah's Witnesses' refusal of blood: obedience to scripture and religious conscience", Journal of Medical Ethics, 1999, Vol. 25, page 471. Muramoto recommends doctors have a private meeting with patients to discuss their wishes, and that church elders and family members not be present, enabling patients to feel free of church pressure. He suggests doctors question patients on (a) whether they have considered that the Watch Tower Society might soon approve some medical practices they currently find objectionable, in the same manner that it has previously abandoned its opposition to vaccination and organ transplants; (b) whether Witness patients know which blood components are allowed and which are prohibited, and whether they acknowledge that those rulings are organizational policy rather than biblical teachings; and (c) whether they realize that although some Bible scriptures proscribe the eating of blood, eating and transfusing blood have entirely different effects on the body.
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Whenever a red cell transfusion is being considered for an individual patient it is good practice to consider not only the hemoglobin level, but also the overall clinical context, patient preferences, and whether there are alternative treatments. If a person is stable and has a hematinic deficiency they should be treated for the deficiency (iron deficiency, B12 deficiency, or folate deficiency) rather than being given a red cell transfusion. In adults blood transfusion is typically recommended when hemoglobin levels reach 70 g/L (7 g/dL) in those who have stable vital signs, unless they have anemia due to a hematinic deficiency. Transfusing at a restrictive hemoglobin threshold of between 70 g/L to 80 g/L (7 to 8g/dL) decreased the proportion of people given a red blood cell transfusion by 43% across a broad range of clinical specialities, including those people who are critically ill.
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He makes mention of a "queer hooting" sound, but attributes it to the exhalation of air prior to fatally transfusing blood from their human victims. Some evidence of audible communication is associated with the Martian Fighting-Machine, which are described emitting siren-like calls, and the repeated "Ulla, ulla" call (similar to a distress signal) that echoes throughout London after the mass death from bacterial infection of the Martians. Despite their advancement, the Martians' technology lacks the wheel, and it is implied they are ignorant of disease and decomposition. It is theorized that their advanced technology eliminated whatever indigenous diseases were present on Mars, and so they no longer remembered their effects. Ultimately, their lack of knowledge or preparation against any bacteria indigenous to Earth, causes their destruction here (though the epilogue states they may have successfully invaded Venus) by what Wells described as “putrefactive bacteria,” which digests organic materials upon death.
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