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73 Sentences With "therapeutical"

How to use therapeutical in a sentence? Find typical usage patterns (collocations)/phrases/context for "therapeutical" and check conjugation/comparative form for "therapeutical". Mastering all the usages of "therapeutical" from sentence examples published by news publications.

Doctor is an author of numerous scientific studies and books with therapeutical fairy tales, characters of which are prototypes of real people: his patients and friends.
But just as a healthy houseplant can have real therapeutical benefits, the death of a houseplant can have real psychological and emotional effects, especially considering the parental connotation we've given plant care.
However it is an example of individualized genomic medicine therapeutical intervention.
He then addresses therapeutical approaches to understanding interpersonal relationships, in particular also the therapist–patient relationship.Yalom (1980), Existential Psychotherapy, Chapter 9.
Some DMARDs (e.g. the purine synthesis inhibitors) are mild chemotherapeutics, but use a side effect of chemotherapy—immunosuppression—as their main therapeutical benefit.
It has been used as a well-established therapeutical resource since the early 20th century. Back then, various devices were used including vibrating devices to stimulate the muscles.
Modulating the pyrimidine metabolism pharmacologically has therapeutical uses. Pyrimidine synthesis inhibitors are used in active moderate to severe rheumatoid arthritis and psoriatic arthritis, as well as in multiple sclerosis. Examples include Leflunomide and Teriflunomide.
Due to its antiglucocorticoidal activity, mifepristone is investigated for its therapeutical potential in indications like Cushing's syndrome, Alzheimer's disease or psychosis. Beside that SPRMs are under development for various gynecological applications, including estrogen-free contraception, uterine leiomyoma and endometriosis.
He published some popularized essays on psychology which he collected in the book Fri vokster which was published in 1949. This was the first book which introduced Wilhelm Reich's theories and therapeutical practice to a Norwegian audience (Dannevig, 1975).
The first English-language report of melanoma was presented by an English general practitioner from Stourbridge, William Norris in 1820. In his later work in 1857 he remarked that there is a familial predisposition for development of melanoma (Eight Cases of Melanosis with Pathological and Therapeutical Remarks on That Disease). Norris was also a pioneer in suggesting a link between nevi and melanoma and the possibility of a relationship between melanoma and environmental exposures, by observing that most of his patients had pale complexions.Norris W. Eight cases of Melanosis with pathological and therapeutical remarks on that disease.
The frequent association of anti-LKM-1 antibodies and hepatitis C virus (HCV) infections and the probable existence of an infectious and autoimmune form of anti-LKM-1-associated hepatitis, requiring different therapeutical strategies, necessitates the exact determination of anti-LKM-1 specificities.
I used to wake up very early, I liked seeing the junkies, fucked up, give them therapeutical kisses, and dangerous kisses for the prostitutes: only the resisting ones, the ones who were not defeated by the previous night yet. Now I always wake up late.
Although he practices intensely the diagnosis and treatment of Respiratory illnesses in general, His main areas of interest are: Diagnostic and Therapeutical Respiratory Endoscopy, Diagnosis and Treatment of Lung Cancer, Respiratory Infections specially pneumonias in ICU, the study of problems and treatment of Smoking, treatment of Respiratory Sleep Disorders and lecturing Pneumology.
One of the most popular skiing resorts of Turkey is located at Mount Uludağ, just next to the city proper. Bursa's thermal baths have been used for therapeutical purposes since Roman times. Apart from the baths that are operated by hotels, Uludağ University has a physical therapy centre which also makes use of thermal water.
Until the end of the year, another surgical department under the leadership of Leon Solomonovich Astvatsaturov started operating. Children department of Nikolaev hospital took one of the repaired barracks and calculated 30-40 beds. In the same building a nursery for the hospital staff was organised. The therapeutical department under the leadership of Perfiliev was designed for 70 beds.
This structure is both a medical and architectural landmark. Before this hospital, Pensacola had only a scattering of local clinics in converted houses. Doctors would send patients with serious cases as far away as New Orleans for complicated procedures not available in Pensacola. With this facility, Pensacola had the first surgical, radiological, bacterial, and therapeutical facilities in Florida.
Other negative results regarding dissociative amnesia and state dependent memory include: anxiety, depression, social dysfunction, and psychosis. A study done on a sixty year old man whose house burned down showed these effects. After a series of therapeutical sessions, the patient experienced episodes of epilepsy and conveyed feelings of distressed when given retrieval cues alluding to the house fire.
The family contains plants with various therapeutical and other uses in places such as China, Laos, Japan, Thailand, and others. Some members are used for making an insecticide. In Laos, people use them against fleas and lice by making an infusion which they drink to make their blood poisonous. Plants from the family are used for the preparation of a fish poison.
Some tumors, such as glioblastomas, medulloblastoma, and neuroblastoma, are much more sensitive to the methionine starvation than the normal tissues. Therefore, methionine depletion arises as a relevant therapeutical approach to treat cancer. For that reason, MGL has been studied to decrease the methionine levels in the blood serum and decrease the tumor growth and also to kill, by starvation, those malignant cells.
Kv1.3 is already linked with proliferation of lymphocytes, vascular smooth cells, oligodendrocytes and cancer cells. Recent studies have shown that there is therapeutical potential for Kv1.3-blockers such as Margatoxin. In a minipig treatment a study with margatoxin has been conducted. An eight-day treatment led to a prolonged immune suppression that lasted three to four weeks after termination of dosing.
FlutemazepamGB Patent 1431282 - Benzodiazepine Compounds for Therapeutical Use. was developed at a team at Stabilimenti Chimici Farmaceutici Riuniti SpA in the mid 1970s. Is a drug which is a 3-hydroxy benzodiazepine derivative and an analogue of temazepam that has hypnotic, sedative, amnesiac, anxiolytic, anticonvulsant and skeletal muscle relaxant properties. It is most closely related in structure to temazepam and is indicated for the treatment of severe insomnia.
However, the findings related to the role of campothecin and its potential therapeutical use were reaffirmed in the study by Zhang et al. conducted in patients with keloid.Zhang, Guo-You; Gao, Wei-Yang; Li, Xuan; Yi, Cheng-Gang ; Zheng, Yan; Li, Yang; Xiao, Bo; Ma, Xian-Jie; Yan, Li; Lu, Kai-Hua; Han, Yan; Guo, Shu-Zhong. Effect of Camptothecin on Collagen Synthesis in Fibroblasts From Patients With Keloid.
"Our sound is a little bit different from our old sound, [but] it's like something that we would have done but on another level. Like the new version of who we are [...]." Lyrically, "Departed" chronicle a woman's talks about mutual support with loved ones. Recorded with therapeutical background, Norwood has noted the fatal 2006 car accident, in which she was involved, as a reason for its inclusion on the album.
It is currently not approved in the USA. Where approved, Fibrolan has been licensed on the basis of claimed good therapeutical experience, but adequate and well controlled studies are still lacking. In the past, combinations with the antibiotic chloramphenicol were available, but because chloramphenicol in any form of application has led to aplastic anemia and death, these were banned. Additionally, combinations with the antifibrinolytic agent tranexamic acid have been withdrawn from pharmaceutic markets.
The efficacy and safety of flunoxaprofen has been compared with those of Naproxen in rheumatoid arthritis patients to show that the two drugs have equivalent therapeutical effects. Both drugs significantly relieve spontaneous pain which occurs both during the day and at night. Both drugs also significantly relive the pain associated with active and passive motion and aid in relieving morning stiffness. The study also showed both drugs to be equally effective at improving grip strength.
Glenn argues that the conversational aspect of the rituals may have therapeutical effects. Members from all Venezuelan social classes participate in the rituals. In local reports, the rituals have been considered to be linked with the late president of Venezuela Hugo Chávez, yet there is little to no evidence. Chávez himself said he did not take part in it, and some followers of María Lionza have said to support him while others dislike Chávez.
Using immunohistochemistry, calretinin can be demonstrated in both benign mesothelium and in malignant mesothelioma and can be used to help differentiate different lung tumours. Antibodies to calretinin can also be used to distinguish between different types of brain tumour, demonstrating only those with neuronal rather than glial, differentiation. Furthermore, the essential function of calretinin in mesothelioma cell lines has been demonstrated in vitro and may be an interesting target for therapeutical approaches.
These conditions along with many others push and motivate most Copts to rely on the Church for its consistent therapeutical and medical support. However, the most significant factor of Church reliance is the passing of folklores. Since there have been many stories of healings, Egyptians pass certain traditions and stories among their friends and families. In recent time, a Priest named Father Makary Younan has performed many spiritual healings in his church Saint Mary and Saint Makar in Oleya.
By the growing number of tuberculosis patients coming to Davos Carl Rüedi was well off. Within few years Rüedi gained an excellent reputation among his clientele. By the end of 1878 Rüedi resigned his post of a district doctor and concentrated on his activities as a private doctor. Rüedi's therapeutical successes were due to a combination of medical competence and the high-Alpine climate of Davos (altitude 1.560 m / 5,118 ft) with its cool, clean and dry air.
Bob Connolly is the author of a print book titled Dynamic Media – Music, Video, Animation and the Web. According to Pearson Publishing's press release, this book was the first of its kind by offering an interactive rich media PDF on CDROM which is bundled with the book. The book/CDROM eBook teaches you how to make interactive eBooks in PDF. Connolly is also an expert in the positive therapeutical aspects of electromagnetic fields and lectures on the subject.
Antihistamines are also consumed in combination with alcohol, particularly by youth who find it hard to obtain alcohol. The combination of the two drugs can cause intoxication with lower alcohol doses. Hallucinations and possibly delirium resembling the effects of Datura stramonium can result if the drug is taken in much higher than therapeutical dosages. Antihistamines are widely available over the counter at drug stores (without a prescription), in the form of allergy medication and some cough medicines.
Secondly, Ruth Cohn was dissatisfied with her finding that therapeutical groups were so full of human encounters and experiences, wereas the life in class rooms was so academic, so abstract. It should be possible to form and lead learning and work groups in such a way that there would be some activation by lively dialogue, some self-determination, some personal engagement. The answer was TCI. At the beginning of 1960s Ruth Cohn worked in commercial enterprises using TCI for the first time.
However, resistance to trimethoprim and other drugs aimed at DHFR can arise due to a variety of mechanisms, limiting the success of their therapeutical uses. Resistance can arise from DHFR gene amplification, mutations in DHFR, decrease in the uptake of the drugs, among others. Regardless, trimethoprim and sulfamethoxazole in combination has been used as an antibacterial agent for decades. Folate is necessary for growth, and the pathway of the metabolism of folate is a target in developing treatments for cancer.
Saig bei Lenzkirch is a small village and health resort with therapeutical climate in the community of Lenzkirch, district of Breisgau-Hochschwarzwald in the German state of Baden-Württemberg.Lenzkirch Wanderparadies im Hochschwarzwald It has a surface area of 11,03 km2 and a resident population of 1023, 777 in the urban area (as of 31 December 2014).Lenzkirch: Fläche, Bevölkerung, Zweitwohnsitze, ... Saig derives its name from Seigge, a German word for watershed as it lays in the divide between the Rhine and the Danube.
After purine itself was isolated, a variety of derivatives were prepared, some of which were patented in view of possible therapeutical applications. Fischer is particularly noted for his work on sugars. Among his early discoveries related to hydrazine was that phenylhydrazine reacted with sugars to form substances which he named osazones, and which, being highly crystalline and readily formed, served to identify such carbohydrates more definitely than had been previously possible. Later, among other work, he is noted for the organic synthesis of D-(+)-glucose.
However, there are studies that show Aparf1 and caspase-9 have independent roles other than the apoptosome so altering their levels could alter cell function as well. So despite encouraging experimental data several problems remain unsolved and limit the use of experimental drugs in clinical practice. The discovery of apoptosome inhibitors will provide a new therapeutical tool for the treatment of apoptosis mediated disease. Of particular importance are those new compounds able to inhibit apoptosome stability and activity, by acting on intracellular protein–protein interactions without altering the transcriptional levels of the apoptosome components.
Consumption in smaller quantities have been found to be of therapeutical value, especially amongst people who suffer from sleeping disorders. Kava is used to calm anxiety, stress, and restlessness, and treat sleep problems (insomnia). It is also used for attention deficit-hyperactivity disorder (ADHD), epilepsy, psychosis, depression, migraines and other headaches, chronic fatigue syndrome (CFS), common cold and other respiratory tract infections, tuberculosis, muscle pain, and cancer prevention.Some people use kava for urinary tract infections (UTIs), pain and swelling of the uterus, venereal disease, menstrual discomfort, and to arouse sexual desire.
Ammoniacum has a faintly fetid, unpleasant odor, which becomes more distinct on heating; externally, it possesses a reddish-yellow appearance, and when the tears or lumps are freshly fractured they exhibit a waxy luster. It is chiefly collected in central Persia, and comes to the European market by way of Bombay. Ammoniacum is closely related to asafoetida and galbanum (from which, however, it differs in yielding no umbelliferone) both in regard to the plant which yields it and its putative therapeutical effects. Internally it is used in conjunction with squills in bronchial affections.
Today his most historically significant contribution to science is his work on the psychogenics of psychiatric and mental illnesses, such as hysteria. For the first time in the German-speaking world he postulated psychological causes of disease. For this reason and because of his convincing arguments for the therapeutical effects of electrotherapy, Sigmund Freud referred to Möbius as one of the fathers of psychotherapy. A further important contribution is to have given his friend, the psychiatrist Emil Kraepelin (1856-1926), important ideas to the differentiation and systematisation of mental illness.
However, this "prohibition does not succeed in abolishing" the desire to touch; all it can do is repress the desire and "force it into the unconscious". p. 29. Freudian psychoanalysis remained the dominant treatment for OCD until the mid-1980s, even though medicinal and therapeutical treatments were known and available, because it was widely thought that these treatments would be detrimental to the effectiveness of the psychotherapy. In the mid-1980s, psychiatry made a sudden "about-face" on the subject and began treating OCD primarily through medicine and practical therapy rather than psychoanalysis.
He established the Zander Therapeutical Institute in Stockholm. In 1880 he became a lecturer of the Stockholm University, and in 1896 he became a member of the Royal Swedish Academy of Sciences. Zander exhibited his Institute at the 1876 Centennial Exhibition in Philadelphia where his exercise machines won a gold medal.Carolyn Thomas de la Pena The Body Electric: How Strange Machines Built the Modern American New York University Press (2003) p72 By 1906 he had established Institutes in 146 countries, and by 1910 "ample numbers of Americans were familiar with the machines".
The Institute for Therapy through the Art is a non-profit creative arts therapy organization in Evanston, Illinois, in the United States. It was founded in 1975 by Marilyn Richman, a drama therapist and co-founder of the North American Drama Therapy Association (NADTA), as a division of the Music Institute of Chicago, with the help of Frank Little, the director at the time. In 2015, the ITA's 40th anniversary, ITA became its own independent non-profit organization. ITA provides therapeutical services in art, drama, dance/movement and music therapy.
The H3-receptor is a promising potential therapeutical target for many (cognitive) disorders that are caused by a histaminergic H3R dysfunction, because it is linked to the central nervous system and its regulation of other neurotransmitters.Bolam, J. Paul, and Tommas J. Ellender. “Histamine and the Striatum.” Neuropharmacology 106 (July 2016): 74–84Sadek, Bassem, Ali Saad, Adel Sadeq, Fakhreya Jalal, and Holger Stark. “Histamine H3 Receptor as a Potential Target for Cognitive Symptoms in Neuropsychiatric Diseases.” Behavioural Brain Research 312 (October 2016): 415–430 Examples of such disorders are: sleep disorders (including narcolepsy), Tourette syndrome, Parkinson, OCD, ADHD, ASS and (drug)addictions.
"Spannabis" convention, 2010 In October 2005, the autonomous government in the region of Catalonia launched a program of therapeutical use of Sativex for 600 patients of a wide set of illnesses, from multiple sclerosis to cancer, in order to avoid nausea or to relax tense muscles. The project involves six hospitals, forty researchers and sixty drugstores. The product is presented as an atomizer to be taken orally, and it will be delivered at drugstores inside some hospitals. The full text of the research initiative can be seen here, in Catalan, from the Universitat Autònoma de Barcelona.
Visa Vuorio (Tobias Zilliacus), a 35-year-old team leader at the Helsinki city gardening department, is suffering from a terminal neurological disease and only has a few months to live. Because of this, he is a member of a therapeutical support group for people suffering from terminal diseases. Visa's life changes when a young female reporter, Hanna Manninen (Helena Vierikko), arrives at the support group offering to write a series of articles about Visa's life story. While visiting the doctor, Visa hears there's been a mix-up of samples, and he is in fact perfectly healthy.
Mystim GmbH was founded in 2005 by Christoph Hofmann. According to him,Interview Christoph Hofmann, Bürgerblatt Mömbris 25/2013ETO Magazine, Birmingham, September 2013, page 30 the founding was a direct reaction to the increasing demand he noted during his work for a medical engineering company that produces electric current devices and applications for therapeutical and medical use. The brand Mystim was to manufacture specialized products that allow electric current to be used safely and risk free in an erotic context. The e-stim devices for instance conform to the German law and secondary legislation for medical devices.
Article 6 of the law integrates the Italian Penal Code with Articles 583-Bis and 583-Ter, punishing any practice of female genital mutilation "not justifiable under therapeutical or medical needs" with imprisonment ranging from 4 to 12 years (3 to 7 years for any mutilation other than, or less severe than, clitoridectomy, excision or infibulation). Penalty can be reduced up to if the harm caused is of modest entity (i.e. if partially or completely unsuccessful), but may also be elevated up to if the victim is a minor or if the offense has been committed for profit.
Kriz argues that psychotherapy research usually neither does justice to the fact of non-linear courses in development and change processes nor does it take the human being as subject into account. The conditions for research would not only be determined by manualizedIn psychotherapy, manualization describes the definition and formalization of therapeutical interventions and steps in a procedural instructional book. effects or interventions, but also to a large extent by the patients' subjective attributions of meaning as well as their interpretations. This, however, makes the so-called "independent variables" of an experimental design dependent on interpretations.
In 1908 he married for the second time, to Margaret Nicholson of St. Louis, whose father was W. A. Nicholson. He was a member of the Republican Party, a Freemason and Shriner affiliated with St. Louis Keystone Lodge No.243, (A.F. & A.M.) and a supporter of the Missouri Athletic Club. He was a member of Pi Gamma Mu fraternity, a Fellow of the London College of Psychotherapy, a member of the Authors League of America; a member of the American Society of Psychical Research; a member of the Society of Rosicrucians; a member of the American Suggestive Therapeutical Association; and a member of the Science League of America.
This constraint has long been considered as the distinctive characteristic of vanilloid antagonism. Capsazepine competes for the capsaicin-binding site on TRPV1 however, due to low metabolic stability and poor pharmacokinetic properties the compound did not reach into clinical development. It was observed later on that this tether was not critical for activity as powerful antagonists free from this structural feature were developed, with 1,3-di(arylalkyl)thioureas emerging as one of the most promising non-vanilloid class of TRPV1 antagonist showing excellent therapeutical potential in pain regulation. Within these compounds, the replacement of the guaiacyl moiety of capsaicinoids with a 3-fluoro-4-sulfonylamido group found critical to revert activity.
Celedonio Calatayud.Celedonio Calatayud Costa (, October 29, 1880 in Pedreguer – January 24, 1931 in Madrid) was a Spanish scientist and radiologist, remembered for his achievements on radiology, radiotherapy, and electrology. He pioneered the use of radiology and electrology in Europe for both diagnostics and therapeutical purposes, introducing radiotherapy in Spain in 1906. He founded the Spanish Medical Electrology and Radiology Society (Sociedad Española de Radiología y Electrología Médicas),Spanish National Library - La Esfera, December 28, 1918 promoted the doctoral chair of Electro- radiology and was elected as the first professor to chair itSpanish National Library, Heraldo de Madrid - August 12, 1920 at the Universidad Central (later renamed Complutense University of Madrid).
These SNPs were located in the gene encoding complement factor H, which was an unexpected finding in the research of ARMD. The findings from these first GWA studies have subsequently prompted further functional research towards therapeutical manipulation of the complement system in ARMD. Another landmark publication in the history of GWA studies was the Wellcome Trust Case Control Consortium (WTCCC) study, the largest GWA study ever conducted at the time of its publication in 2007. The WTCCC included 14,000 cases of seven common diseases (~2,000 individuals for each of coronary heart disease, type 1 diabetes, type 2 diabetes, rheumatoid arthritis, Crohn's disease, bipolar disorder, and hypertension) and 3,000 shared controls.
Highlighted by AllMusic and Slant Magazine, Newsday writer Glenn Gamboa noted it as "guiding principle" on the album. Lead single "Right Here (Departed)" was not recorded until late into the production of Human and the first song Brandy recorded with Jerkins following their musical reunification in early June 2008. Written by The Writing Camp and recorded with therapeutical background, the track chronicles a woman's talks about mutual support with loved ones. It reached number-one on the Billboard Hot Dance Club Play chart, number 22 on the Hot R&B;/Hip-Hop Songs chart and the top ten of the French Singles Chart, becoming Brandy's biggest chart success in years.
R. La Roche, Yellow Fever, Considered in its Historical, Pathological, Etiological, and Therapeutical Relations, Philadelphia, 1855, 525. On March 28, 1803, the Legislature passed an act to incorporate that part of the township of the Northern Liberties lying between the west side of Sixth Street and the Delaware River and between Vine Street and Cohocksink Creek, thus creating the District of Northern Liberties. Under the Act of Consolidation, 1854, the district ceased to exist, and became a part of Philadelphia. Early in its history, the location just outside Philadelphia allowed the area to thrive in manufacturing, as mills, breweries, leather tanneries, paints and chemical works, tool making factories, and iron and stove foundries once lined the neighborhood.
A newly developed group therapy model based on Cognitive Behavioral Therapy (CBT) integrates knitting into the therapeutical process and has been proven to yield reliable and promising results. The foundation for this novel approach to CBT is the frequently emphasized notion that therapy success depends on the embeddedness of the therapy method in the patients' natural routine. Similar to standard group- based Cognitive Behavioural Therapy, patients meet once a week in a group of 10 to 15 patients and knit together under the instruction of a trained psychologist or mental health professional. Central for the therapy is the patient's imaginative ability to assign each part of the wool to a certain thought.
The Center has a strong international orientation. It addresses themes such as political socialization, protest activity, political participation, participation in political parties, trade unions and social movements, lobbying and interest groups. CRAPUL has grown ever since its creation in September 2002, especially regarding conferences, the launching of collective research projects and a new series in social sciences at a Swiss publisher. Fillieule's main fields of research and publication refer to social movements theories, the sociology of militantism and political activism, interactionist approaches, commitment and disengagement, gender approaches to social movements and activism, collective behavior, demonstrations, maintenance of order, police and repression and protests and mobilizations against AIDS, therapeutical activism, commitment in vaccine trials.
After introducing the endomyocardial biopsy (EMB) procedure at AIIMS in 1986, he deployed the technique in the evaluation and diagnosis of tropical heart muscle diseases, and his findings on the occurrence of inflammatory myocarditis in Takayasu's arteritis patients have been documented, the first instance the topic was published in medical literature. He also proposed therapeutical protocol for reversing the myocardial dysfunction using immunosuppressants. He established radiofrequency ablation facility in 1992 at AIIMS as a therapeutic procedure for remedying Cardiac arrhythmia and three years later, he introduced Implantable cardioverter-defibrillator implantation procedure in 1995, the first time the procedure was performed in South Asia. The effort earned him a mention in the 1997 edition of the Limca Book of Records.
Consequently, he was often received with significant hostility at professional conferences and in print.Dr. Mike and Dr. Lidia Abrams: A Brief Biography of Dr. Albert Ellis 1913–2007 He regularly held seminars where he would bring a participant up on stage and treat them. His own therapeutical style was famed for often being delivered in a rough, confrontational style; however, it should not be confused with his rational-emotive and cognitive- behavioral therapy school that is practiced by his students and followers in a large variety of therapeutic styles (e.g., often depending on client's personality, client's clinical problem, and evidence-based information regarding the appropriate intervention, but also including therapist's own preference).
Yalom recites examples in literature, case studies and therapeutical implications concerning situations in which persons avoid responsibility. He discusses therapeutic approaches to disorders of wishing, willing and deciding, among them Viktor Frankl's paradoxical intention, which he equates with the "symptom prescription" approach in the writings of Don Jackson, Jay Hayley, Milton Erickson and Paul Watzlawick. A further approach he presents is Fritz Perls' approach of asking patients to re-enact a dream and to play the parts of all the objects in the dream drama. He adds however that Perls, although requesting patients to assume responsibility, had a so active and powerful style that he placed patients in a contradictory situation, leading to a double bind.
In the late 1990s, German healthcare regulators began to voice their doubts over the therapeutical usage of acupuncture, mostly because of the lack of reliable evidence regarding its therapeutic efficacy. This resulted in a heated debate, which led to Paul Rheinberger, Director of the Federal Committee of Physicians and Health Insurers, saying: "The higher the quality of clinical studies performed on acupuncture, the lesser the amount of evidence supporting its efficacy." In October 2000, the Federal Committee of Physicians and Health Insurers decided that acupunctural treatment may not be reimbursed by statutory health insurance companies except within the framework of experimental field studies. In 2001 the GERAC were set up at Bochum University as a field study on behalf of six German statutory health insurance organizations.
Skp2 is of considerable interest as a novel and attractive target for cancer therapeutical development, as disrupting the SCF complex will result in increased levels of p27, which will inhibit aberrant cellular proliferation. Although Skp2 is an enzyme, its function requires the assembly of the other members of the SCF complex. As Skp2 is the rate-limiting component of the SCF complex, effective inhibitors should be focused on the interfaces of Skp2 with the other members of the SCF complex, which is much more difficult than traditional enzyme inhibition. Small molecule inhibitors of the binding site between Skp2 and its substrate p27 have been discovered, and these inhibitors induce p27 accumulation in a Skp2-dependent manner and promote cell cycle arrest.
In 2007, Barros Franco was nominated Chief of Pneumology, Respiratory Endoscopy and Sleep Disorder Service of Casa de Saúde São José, a private hospital in Rio de Janeiro with 300 beds. It is a complete and modern service that offers specialized evaluations, diagnostical and therapeutical respiratory endoscopy, pulmonary effort exams, surgical risk assessment, smoking treatment and Sleep disorder laboratory. In PUC-RIO he coordinates the institution's Specialization Course in Pneumology that is accredited by both the Brazilian Pneumology Society (Sociedade Brasileira de Pneumologia) and Brazilian Medical Association (Associação Médica Brasileira). He also lectures on specialized courses in Pneumology, Respiratory Endoscopy, Pulmonary Oncology, Sleep Disorder and the I Course on Smoking, first in the country to qualify health professionals country-wide to handle this public health challenge.
The Hospital Pasteur was built during the first years of the 20th century in front of the institute, and was employed for a long time by the members as a field for clinical observation and experimentations of therapeutical processes elaborated by themselves. Since in the beginning it was provided with only 120 beds, every patient was so well isolated in his private room that each room could be almost considered a small pest house, ideal for quarantine. The construction of the hospital was enabled by the gift of a rich benefactor, Madame Lebaudy, while the money offered by another rich woman, the baroness Hirsch, was used to build a vast pavilion that accommodated the Department of Chemical Biology of the institute.
In recent years, some politicians have begun to debate the possibility of institutionally constituting Insubria and/or gaining its political autonomy. However, as of today there exist no political parties striving for that goal, but only some cultural and opinion movements. At the beginning of 2002 the "Movimento degli Indipendenti Insubrici" ("Insubrian Independence Movement") was constituted in the Ticino Canton, and later in the Graubünden Canton. It was led by Werner Nussbaumer, a physician from Gravesano, former member of the Greens and known for his actions aimed at promoting Cannabis indica for therapeutical purposes. The "Indipendenti Insubrici" had Nussbaumer as their representative in the Gran Consiglio of the Ticino Canton from January 2003 to the following elections in the same year, though he had been originally elected in 1999 among the Greens.
There is little doubt that the capacity for using psychiatry to enforce social norms and even political interests is immense. Now psychiatry is vulnerable because many of its notions have been questioned, and the sustainable pattern of mental life, of boundaries of mental norm and abnormality has been lost, director of the Moscow Research Institute for Psychiatry Valery Krasnov says, adding that psychiatrists have to seek new reference points to make clinical assessments and new reference points to justify old therapeutical interventions. As Emmanuil Gushansky states, today subjective position of a Russian patient toward a medical psychologist and psychiatrist is defensive in nature and prevents the attempt to understand the patient and help him assess his condition. Such a position is related to constant, subconscious fear of psychiatrists and psychiatry.
The head of the ÍSÍ board of health, Birgir Guðjónsson, was highly criticised for his actions in the case. The Icelandic Basketball Federation claimed that he offered to minimize punishment for two male basketball player who were charged and later suspended for the use of effedrin, an offer he had no legal grounds to make, if Kristín would admit to a wrongdoing. The claim was backed up by another member of the board of health who was present during the meeting. He was further criticised for not disclosing an email from Francoise Jascinski of FIBA that stated that if Kristín had prescriptions from a doctor for using the drug in question, which she did, then there was therapeutical justification for its use and no sanctions should apply for her per FIBA regulations.
Therefore, the behavior-guiding individual social identity of out- group members is strongly influenced by the stigmatizing labels applied by the majority in-group, and prejudice may yield the very pathological traits, the very aggressive, harmful, even criminal behavior in individual out-group members that out-groups are said to indulge in. In short, the majority in- group's dominant prejudices can thereby result in a self-fulfilling prophecy, a process which Bleibtreu-Ehrenberg dubs "self-maintenance of prejudice" (Selbststabilisierung des Vorurteils). For this reason, Bleibtreu-Ehrenberg dedicated Angst und Vorurteil to the prefaced motto Minderheitenschutz ist Mehrheitenschutz ("Protecting minorities (from prejudice) helps protect the majority.") Furthermore, Bleibtreu-Ehrenberg expressly incorporates structural violence of the state, including involuntary medico-therapeutical intervention, as a form of discrimination, considering it a regulating, standardizing dispositif motivating further discrimination by "vigilant" individuals.
Rather, there was a lack of data from reliable scientific investigation into physiological mechanisms, and the means "by which the effects of hydropathy can be measured and controlled". > Probably however, nothing has done more to repel earnest research than the > suspicion of quackery which taints the practice that ordinarily goes by this > name. Huge establishments can only be made to pay by full houses well kept > up, and this is found as a rule to require that their calling be magnified > in ways which are at once too special and popular to be scientific and > genuine. The British Medical Journal concurred with this writer on all counts, noting that there were "simple generalisations" that could be deduced regarding the effects of heat and cold on physiological processes, and lamenting the lack of such generalisations by "therapeutical authorities", let alone scientific investigations.
Population pharmacokinetics is the study of the sources and correlates of variability in drug concentrations among individuals who are the target patient population receiving clinically relevant doses of a drug of interest. Certain patient demographic, pathophysiological, and therapeutical features, such as body weight, excretory and metabolic functions, and the presence of other therapies, can regularly alter dose-concentration relationships and can explain variability in exposures. For example, steady- state concentrations of drugs eliminated mostly by the kidney are usually greater in patients suffering from kidney failure than they are in patients with normal kidney function receiving the same drug dosage. Population pharmacokinetics seeks to identify the measurable pathophysiologic factors and explain sources of variability that cause changes in the dose-concentration relationship and the extent of these changes so that, if such changes are associated with clinically relevant and significant shifts in exposures that impact the therapeutic index, dosage can be appropriately modified.
After a few cases of infibulation practiced by complaisant medical practitioners within the African immigrant community came to public knowledge through media coverage, the Law n°7/2006 was passed on 1/9/2006, becoming effective on 1/28/2006, concerning "Measures of prevention and prohibition of any female genital mutilation practice"; the Act is also known as the Legge Consolo ("Consolo Act") named after its primary promoter, Senator Giuseppe Consolo. Article 6 of the law integrates the Italian Penal Code with Articles 583-Bis and 583-Ter, punishing any practice of female genital mutilation "not justifiable under therapeutical or medical needs" with imprisonment ranging from 4 to 12 years (3 to 7 years for any mutilation other than, or less severe than, clitoridectomy, excision or infibulation).Italian Law n°7 1/9/2006, Disposizioni concernenti la prevenzione e il divieto delle pratiche di mutilazione genitale femminile, accessed 23 March 2009. The penalty can be reduced up to if the harm caused is of modest entity (i.e.
' Such names would establish a clear distinction between the electricity by contact and that by induction, whilst they, at the same time, render due honour to a philosopher to whom medical science owes a discovery far more valuable in a therapeutical point of view than that of Galvani.'""Medical News, Thursday, August 28th 1851", The Lancet, Volume 2, Publisher Elsevier, 1851 (page 240) It is noted that: :"Some terms such as galvanic current and faradic stimulation are unique to physiotherapy. Their definitions given in the literature are far from universal.Sheila Kitchen, Sarah Bazin, "Section F. Low Frequency Currents", Electrotherapy: evidence-based practice, Volume 1, edition 11, Publisher Elsevier Health Sciences, 2002, , , 347 pages (page 234) ... The Clinical Electrophysiology Section of the American Physical Therapy Association established a unified terminology for clinical electrical currents--that is, (a) direct current (b) alternating current (c) pulsed current (Kloth and Cummings, 1991)Reference in quote to: Kloth LC, Cummings JP, Electrotherapeutic Terminology in Physical Therapy, 1991, Alexandria, VA: American Physical Therapy Association.
The following accounts indicate how bad the situation was: > A small stream of water, called Pegg's Run, passes through a portion of the > Northern Liberties and Spring Garden, which, until a few years ago, was left > open and unimproved. The bottom of the stream was miry, and, at low tide and > in hot and droughty weather, was often destitute of sufficient water to > carry off its contents. Receiving the offals of very many slaughter-houses, > lanyards, glue, starch, dressed skin, and soap manufactories adjoining it, > as well as the contents of two culverts, of a large number of privies, and > of the gutters of the numerous populous streets and alleys it crosses, it > became highly offensive, and the source of noxious exhalations. This stream, > which plays a conspicuous part in the history of one of the epidemics, and > was correctly pronounced the greatest nuisance in Philadelphia, attracted > finally the attention of the public and council, and has since been > culverted. \--From René La Roche, Yellow Fever, Considered in Its Historical, Pathological, Etiological, and Therapeutical Relations... (Blanchard and Lea, 1855), at 27-28.
As of 2014 no biomarker with perfect correlation has been found, but some of them have shown a special behavior like IgG- and IgM- oligoclonal bands in the cerebrospinal fluid and autoantibodies against neurotropic viruses (MRZ reaction) and the potassium channel Kir4.1. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes or pharmacological responses to a therapeutic intervention. Type 0 biomarkers are those related to the course a pathogenic process and type 1 are those that show the effects of the therapeutical intervention. As of 2014, the only fully specific biomarkers found to date are four proteins in the CSF: CRTAC-IB (cartilage acidic protein), tetranectin (a plasminogen-binding protein), SPARC-like protein (a calcium binding cell signalling glycoprotein), and autotaxin-T (a phosphodiesterase) Nevertheless, abnormal concentrations of non-specific proteins can also help in the diagnosis, like chitinases This list has been expanded in 2016, with three CSF proteins (Immunoglobulins) reported specific for MS. They are the following immunoglobulins: Ig γ-1 (chain C region), Ig heavy chain V-III (region BRO) and Ig-κ-chain (C region).

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