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62 Sentences With "skin discoloration"

How to use skin discoloration in a sentence? Find typical usage patterns (collocations)/phrases/context for "skin discoloration" and check conjugation/comparative form for "skin discoloration". Mastering all the usages of "skin discoloration" from sentence examples published by news publications.

Using hydroquinone on a long-term basis can cause skin discoloration by lightening it too much.
"There's enough lactic acid in yogurt to provide a mild bleaching effect that could help even skin discoloration," he says.
" Other effects can include "burning, rash, itching, skin discoloration/redness, blistering, allergic type reactions including hives/welts, allergic contact dermatitis, and bleeding also have been reported.
Complications such as infection, poor wound healing and skin discoloration still occur in a small number of cases, according to the American Society of Plastic Surgeons.
Through stimulating the normal lymph flow within the body and helping to detoxify it naturally, dry body brushing suppresses the formation of cellulite, varicose veins, and skin discoloration.
Mundy -- who was part of the Steelers' Super Bowl 43 squad -- says he got the wound stitched up ... but he now has permanent skin discoloration at the scar site.
The pair returned to the doctor, who again prescribed medication, and diagnosed the boy with eczema "based on the aggressive spreading of the rash" and skin discoloration, according to the documents.
At the hospital, tests showed that he had kidney damage and signs of liver dysfunction, and doctors observed dark spots all over his face and skin discoloration on his lower body.
The treatment – most commonly used to treat scars, wrinkles, acne scars and sun damage – improves skin tone, smoothes out fine lines, and evens out skin discoloration by treating tiny sections of the skin at a time.
"Long-term use of inorganic mercury in skin-lightening creams can result in kidney damage, skin discoloration, rashes, toxicity to the kidneys, peripheral neuropathy, and psychosocial issues such as anxiety, depression, and possibly psychosis," Dr. Chiu explains.
In her research on skin bleaching in Tanzania, Lewis-Arthur also found that many women falsely believed that if they just continued to use their lightening products, the acne, skin discoloration and other side effects they caused would disappear.
The lack of sanitation and the unregulated mining operations mean the ground in La Rinconada is heavily contaminated with mercury, resulting in many of the residents suffering from mercury poisoning, which affects​ the nervous system and causes itching, burning, and skin discoloration.
Slipping back and forth between conversational Spanish and English with a man seeking naloxone and fentanyl test strips, she moved methodically step-by-step, beginning with an overview of the physical symptoms of overdose: blue nails or lips, skin discoloration and shallow breaths.
It has anti-inflammatory properties, so it can help with acne; it evens out skin discoloration and hyperpigmentation by inhibiting melanin synthesis through an enzyme; it helps stimulate collagen production, which helps with wrinkles and fine lines; and it brightens, so your skin will look smoother, glowy, energized, and healthy.
The most common adverse effects include redness, skin discoloration and pain. Other side effects include blistering and scarring.
Dec 1983;22(10):590-2. Scarring, postoperative skin discoloration or keloid formation are potential complications. Therefore, conservative DPN treatment is advisable.
Heat generated from using a laptop on the lap can also cause skin discoloration on the thighs known as "toasted skin syndrome".
Chrysiasis can ultimately lead to acute kidney injury (such as tubular necrosis, nephrosis, glomerulitis), severe heart conditions, and hematologic complications (leukopenia, anemia). While some effects can be healed with moderate success, the skin discoloration is considered permanent.
Sunitinib adverse events are considered somewhat manageable and the incidence of serious adverse events low. The most common adverse events associated with sunitinib therapy are fatigue, diarrhea, nausea, anorexia, hypertension, a yellow skin discoloration, hand-foot skin reaction, and stomatitis. In the placebo-controlled Phase III GIST study, adverse events which occurred more often with sunitinib than placebo included diarrhea, anorexia, skin discoloration, mucositis/stomatitis, asthenia, altered taste, and constipation. Dose reductions were required in 50% of the patients studied in RCC in order to manage the significant toxicities of this agent.
Melasma (also known as chloasma faciei,James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. . or the mask of pregnancy when present in pregnant women) is a tan or dark skin discoloration.
A noticeable side-effect of gold-based therapy is skin discoloration, in shades of mauve to a purplish dark grey when exposed to sunlight. Skin discoloration occurs when gold salts are taken on a regular basis over a long period of time. Excessive intake of gold salts while undergoing chrysotherapy results – through complex redox processes – in the saturation by relatively stable gold compounds of skin tissue and organs (as well as teeth and ocular tissue in extreme cases) in a condition known as chrysiasis. This condition is similar to argyria, which is caused by exposure to silver salts and colloidal silver.
He had a scar above his navel and one on the left side of his abdomen, as well as multiple open sores and skin discoloration on his legs. His toes were also misshapen, resulting from an infection. Investigators believe that he may have been from South Florida.
Side effects include skin irritation, sun sensitivity, allergic reactions, and skin discoloration. It is unclear if use during pregnancy is safe for the baby and use during breastfeeding is not typically recommended. The exact mechanism of action is unknown. It is a complex mixture of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.
Due to the numbing sensation of the cold and possible nerve damage during the stunt, participants are often unaware of the extent of any injuries sustained during the challenge, only feeling pain once the salt on their skin enters lesions created during the challenge. Skin discoloration from the challenge may remain after the challenge has been attempted.
He was kept in custody for 153 days, but was given remuneration in 1980. He then met Birgit Hogefeld, and they began dating and moved in together. On February 15, 1987, the Tagesschau on ARD ran a bulletin on Grams and Hogefeld. He was described as tall and with blue green eyes and a striking dark skin discoloration on his face.
Some normal side effects may occur after laser hair removal treatments, including itching, pink skin, redness, and swelling around the treatment area or swelling of the follicles (follicular edema). These side effects rarely last more than two or three days. The two most common serious side effects are acne and skin discoloration. Some level of pain should also be expected during treatments.
There is a risk of skin discoloration and a very small risk of scarring. Exfoliation with various tools such as brushes and loofahs also helps prevent bumps. Some men use electric razors to control PFB. Those who use a razor should use a single blade or special wire-wrapped blade to avoid shaving too closely, with a new blade each shave.
Kasabach–Merritt syndrome has a mortality rate of about 30%. For patients that survive the acute disease, supportive care may be required through a gradual recovery.Furthermore, patients may need care from a dermatologist or plastic surgeon for residual cosmetic lesions or an otolaryngologist for head & neck/airway involvement. On long-term followup, most patients have skin discoloration and/or mild disfiguration from the dormant tumor.
Bismuthia is a rare dermatological condition that results from the prolonged use of bismuth. Much more rarely than with silver, bismuth may produce a generalized persistent skin discoloration resembling argyria. The conjunctivae and oral mucosa, as well as skin, are commonly afflicted by the condition. Pigment granules are evenly scattered through the dermis, producing a blue, or bluish gray skin color by the scattering phenomenon.
Long term effects of acne mechanica include potential scarring and skin discoloration at the area of the acne lesion if rubbing of the skin continues. It is not a lethal condition and the acne will clear up on its own once the heat and pressure stressors are avoided and if the skin is kept clean so the pores do not continue to become clogged.
They were allegedly smuggled into the country and then held for ransom. The captor who had been shot in self defense was an Asian man, between the ages of 22 and 32 years old. He was 5 feet 6 inches tall and weighed 124 pounds. He had black hair and brown eyes as well as scars on his left arm and skin discoloration on his left wrist.
The DHS completed several assessments and studies between 1988 and 1991 that found exposure for the waste was mostly through inhalation, ingestion, and skin contact. Children played with the seep material like ‘silly putty” and used the waste as chewing gum, while adults had skin discoloration and a burning sensation from handling the material during yard excavations. Asthma, allergies, and other respiratory problems plagued sensitive populations due to inhalation exposure.
The symptoms and signs that occur depend on the cyst's location and size. Alveolar disease usually begins in the liver, but can spread to other parts of the body, such as the lungs or brain. When the liver is affected, the patient may experience abdominal pain, weight loss, along with yellow-toned skin discoloration from developed jaundice. Lung disease may cause pain in the chest, shortness of breath, and coughing.
The most common CNS feature is an intracranial hemangioma in the midbrain. Cerebral malformations can result in severe headaches, cerebral hemorrhages, vomiting, meningism, seizures, acute strokes, and progressive neurological deficits due to acute or chronic ischaemia caused by arteriovenous shunting. The facial features of Bonnet–Dechaume–Blanc syndrome vary from case to case. A person showing signs of the syndrome may display faint skin discoloration, nevi, or angiomas of the skin.
Since deoxygenated blood should not be delivered to the tissues, the result is cyanosis, or a bluish skin discoloration stemming from low oxygen concentration. Proper function of Tbx20 is essential because it controls other genes that regulate cardiomyocyte proliferation, such as Tbx2 and N-myc1. Cardiomyocytes are the basis for the correct architectural scheme of the heart, and if defects arise in these structures, proper heart development is likely unattainable.
Symptoms of infection include pain, described as a heaviness or pressure that is disproportionate to physical findings, tachycardia, and hypotension. Tissue necrosis then causes edema and ischemia resulting in metabolic acidosis, fever, and kidney failure. The carbon dioxide and hydrogen produced during cellular respiration move through tissue planes, causing their separation, producing features characteristic of palpable emphysema. This also results in a magenta-bronze skin discoloration and bulla filled with a foul-smelling serosanguinous fluid.
AHAs are generally safe when used on the skin as a cosmetic agent using the recommended dosage. The most common side-effects are mild skin irritations, redness and flaking. The severity usually depends on the pH and the concentration of the acid used. Chemical peels tend to have more severe side- effects including blistering, burning and skin discoloration, although they are usually mild and go away a day or two after treatment.
The adverse effects found in the Phase II trial mainly affected the central nervous system, and appeared to be dose-related. The most common adverse effects were drowsiness, dizziness, tinnitus and vertigo, confusion, and slurred speech. Less common side effects included tremor, memory loss, gait disturbances, and double vision. In 2013 FDA warned the public that, Potiga (ezogabine) can cause blue skin discoloration and eye abnormalities characterized by pigment changes in the retina.
This is a skin disorder that is rare and inherited. It caused by genetics and is an autosomal recessive trait therefore, in order to be affected and present the disease each parent must be a carrier of the mutated allele and pass it to their kids. Inbreeding within families can cause Meleda disease to be prevalent. Meleda disease can be associated with other skin conditions such as skin discoloration, skin thickness, and skin peeling.
Often they are performed in surgical suites or in professional medical centers. Since the procedure can typically remove the top to deeper layers of the epidermis, and extend into the reticular dermis, there is always minor skin bleeding. The procedure carries risks of scarring, skin discoloration, infections, and facial herpes virus (cold sore) reactivation. In aggressive dermabrasion cases, there is often tremendous skin bleeding and spray during the procedure that has to be controlled with pressure.
Clofazimine produces pink to brownish skin pigmentation in 75-100% of patients within a few weeks, as well as similar discoloration of most bodily fluids and secretions. These discolorations are reversible but may take months to years to disappear. There is evidence in medical literature that as a result of clofazimine administration, several patients have developed depression which in some cases resulted in suicide. It has been hypothesized that the depression was a result of this chronic skin discoloration.
Most common side-effects include nausea, vomiting, acid reflux (heartburn), headache, cosmetic reduction in abdominal body fat, light sleeping, and loss of appetite. Less common side effects include faint discoloration of fingernails and toenails, mood elevation, occasional tingling or transient numbness of the hands or feet, and minor skin discoloration. Allergic reactions are rare. Early long- term higher-dose therapy with AZT was initially associated with side effects that sometimes limited therapy, including anemia, neutropenia, hepatotoxicity, cardiomyopathy, and myopathy.
Despite the numerous ailments for which practitioners claim cupping therapy is useful, there is insufficient evidence it has any health benefits and there are some risks of harm, especially from wet cupping and fire cupping. Bruising and skin discoloration are among the adverse effects of cupping and are sometimes mistaken for child abuse. In rare instances, the presence of these marks on children has led to legal action against parents who had their children receive cupping therapy.
Serious adverse effects connected to bevacizumab are infrequent but among those listed are gastrointestinal perforation, arterial thromboembolic events, hypertensive crisis, neutropenia, complications with wound healing, haemorrhage, nephrotic syndrome, heart failure and reversible posterior leukoencephalopathy syndrome. Sunitinib is a small molecule inhibitor which inhibits phosphorylation of VEGF receptor among other receptors. Sunitinib is mostly well tolerated. Common adverse effects which have an incidence rate of 20% are fatigue, asthenia, diarrhea, nausea, dyspepsia, abdominal pain, constipation, hypertension, skin discoloration, altered taste, stomatitis and mild bleeding.
Side effects of coal tar products include skin irritation, sun sensitivity, allergic reactions, and skin discoloration. It is unclear if use during pregnancy is safe for the baby and use during breastfeeding is not typically recommended. According to the National Psoriasis Foundation, coal tar is a valuable, safe and inexpensive treatment option for millions of people with psoriasis and other scalp or skin conditions. According to the FDA, coal tar concentrations between 0.5% and 5% are considered safe and effective for psoriasis.
In clinical practice, toxicity with emtricitabine is unusual. The most common treatment-related adverse events are diarrhea, headache, nausea, and rash. These symptoms are generally mild to moderate in severity, but they caused 1% of clinical trial patients to give up treatment. Skin discoloration, which is typically reported as hyperpigmentation and usually affects either the palms of the hands or the soles of the feet, is reported in less than 2% of individuals and is almost exclusive to patients of African origin.
Coloration is dark bluish grey on top and lighter gray on the bottom, and the head can be brownish shading to light grey around the lip and the jaw. Skin discoloration might be caused by diatoms .They might have white oval scars possibly caused by cookie-cutter sharks. Adult males can also have long white ‘scratch’ scars. Males reach at least 4.4 m (14 ft 5 in) and 800 kg (1,800 lb), whereas females reach at least 4.6 m (15') and 1 tonne (2200 pounds).
Hair coloring involves the use of chemicals capable of removing, replacing, and/or covering up pigments naturally found inside the hair shaft. Use of these chemicals can result in a range of adverse effects, including temporary skin irritation and allergy, hair breakage, skin discoloration and unexpected hair color results. According to the International Agency for Research on Cancer (IARC), in vitro and in vivo studies (in exposed human populations) have shown that some hair dyes and many chemicals used in the hair dyeing process can be considered mutagenic and carcinogenic.
Laser based therapies can be indicated for the treatment of scars, unwanted hair, skin discoloration, and spider veins.Medical Aesthetics Clinical Skin Protocols 2014 It is important that overall health is assessed by a physician to ensure that the symptom being treated (for example, weight gain and excessive hair) is not a sign of an underlying medical condition (like hypothyroidism) that should be stabilized with medical therapies. It is also very important for the medical aesthetician to be inclusive in providing a team approach for minimally invasive facial aesthetic procedures.
In 2016, the Cambodian Ministry of Health warned that cupping could be a health risk and particularly dangerous for people with high blood pressure or heart problems. According to the NCCIH "Cupping can cause side effects such as persistent skin discoloration, scars, burns, and infections, and may worsen eczema or psoriasis". Cupping may cause breaks in the capillaries (small blood vessels) in the papillary dermis layer of the skin, resulting in the appearance of petechiae and purpura. These marks are sometimes mistaken for signs of child abuse when cupping is performed on children.
There is no known cure for this disease but it is not a life-threatening condition and is mainly of cosmetic concern, although, because it can appear so suddenly, so extensively and because it usually leaves permanent discoloration of the skin, it can cause understandable psychological concern. The skin lesions sometimes cause itching, which can be treated by applying cortisone cream. The cortisone cream will only help with the itching and does not improve the discoloration of the skin. Schamberg's disease causes no other symptoms beside skin discoloration and itching.
Aesthetic medicine is a broad term for specialties that focus on altering cosmetic appearance through the treatment of conditions including scars, skin laxity, wrinkles, moles, liver spots, excess fat, cellulite, unwanted hair, skin discoloration and spider veins. Traditionally, it includes dermatology, oral and maxillofacial surgery, reconstructive surgery and plastic surgery. It includes both surgical procedures (liposuction, facelifts, breast implants, Radio frequency ablation) and non-surgical procedures (radio frequency skin tightening, non surgical liposuction, chemical peel, high-intensity focused electromagnetic field, radio frequency fat removal), and practitioners may utilize a combination of both.International Association for Physicians in Aesthetic Medicine, IAPAM.
According to clinical trials with Hemopure, the following adverse events occurred at greater than or equal to 5%: transient yellow skin discoloration, nausea, mild to moderate increase in blood pressure (10 to 20 mm/Hg), vomiting, low urine output, difficulty swallowing, flatulence, and low red blood cell count. The use of Oxyglobin has shown the following common side effects: discoloration of the skin, mucous membranes and urine. Adverse events such as vomiting and melena (dark color feces) can also occur. Dogs with impaired cardiac function and other conditions that are predisposed to circulatory overload can have adverse events after Oxyglobin administration.
Other side effects associated with low-dose COCPs are leukorrhea (increased vaginal secretions), reductions in menstrual flow, mastalgia (breast tenderness), and decrease in acne. Side effects associated with older high-dose COCPs include nausea, vomiting, increases in blood pressure, and melasma (facial skin discoloration); these effects are not strongly associated with low-dose formulations. Excess estrogen, such as from birth control pills, appears to increase cholesterol levels in bile and decrease gallbladder movement, which can lead to gallstones. Progestins found in certain formulations of oral contraceptive pills can limit the effectiveness of weight training to increase muscle mass.
Some independent chemical weapons analysts, after studying initial intelligence reports and video coverage of survivors on state-run television, initially did not believe that the government or rebels had used advanced chemical weapons. Lack of burns, skin discoloration or quarantine measures were noted. The Syrian military appeared initially to believe that chlorine had been used, rather than an organophosphate. One analyst (Bretton- Gordon) cautioned that conventional high explosives can also produce an odor which might be mistaken for chlorine, and that there was no indication from the images he had seen that the chemical agent had been used.
If left untreated, the mortality rate for C. septicum infection nears 100%. A study by Cline and Turnbull offers that diagnosis be based on findings of pain disproportionate to clinical findings or injury, marked tachycardia, discolored or edematous skin, and a gram-stain of bullous drainage showing gram-positive bacilli without spores and few leukocytes. Physical manifestations of infection include pain caused by infiltration of the infected muscle with edema and gas, tachycardia, muscle and skin discoloration, and the presence of a brown, watery discharge with a foul smell within the wounds. Treatment for C. septicum infection includes antibiotic administration, surgical intervention, and hyperbaric oxygen therapy (HBOT).
In addition, prophylactic irradiation of the breasts can be used to prevent it and has minimal side effects, mostly consisting of temporary skin discoloration. Following continued clinical research after the discovery of the effectiveness of HDE for breast cancer in 1944, HDE, most commonly with diethylstilbestrol and to a lesser extent ethinylestradiol, became the standard of care for the treatment of breast cancer in postmenopausal women from the early 1960s onwards. In the 1970s, the antiestrogen tamoxifen was found to be effective for the treatment of breast cancer and was introduced for medical use. Comparative studies found that the two therapies showed equivalent effectiveness, but that tamoxifen had reduced toxicity.
Common symptoms of mercury poisoning include peripheral neuropathy, presenting as paresthesia or itching, burning, pain, or even a sensation that resembles small insects crawling on or under the skin (formication); skin discoloration (pink cheeks, fingertips and toes); swelling; and desquamation (shedding or peeling of skin). Mercury irreversibly inhibits selenium-dependent enzymes (see below) and may also inactivate S-adenosyl-methionine, which is necessary for catecholamine catabolism by catechol-O-methyl transferase. Due to the body's inability to degrade catecholamines (e.g. epinephrine), a person suffering from mercury poisoning may experience profuse sweating, tachycardia (persistently faster-than-normal heart beat), increased salivation, and hypertension (high blood pressure).
In fact, a major part of the cosmetic world is built around capitalizing on enhancing these features. Making eyes and lips appear larger as well as reducing the appearance of any age-related blemishes such as wrinkles or skin discoloration are some of the key target areas of this industry. Doug Jones, a visiting scholar in anthropology at Cornell University, said that there is cross-cultural evidence for preference for facial neoteny in women, because of sexual selection for the appearance of youthful fecundity in women by men. Jones said that men are more concerned about women's sexual attractiveness than women are concerned about men's sexual attractiveness.
Dermatosis neglecta is a skin condition in which accumulation of sebum, keratin, sweat, dirt and debris leads to a localized patch of skin discoloration or a wart-like plaque. It is caused by inadequate hygiene of a certain body part, usually due to some form of disability or a condition that is associated with pain or increased sensitivity to touch (hyperesthesia) or immobility. Dermatosis neglecta typically develops several months after a disability or other affliction leads to improper cleaning. Patients may deny that negligence is the cause of the lesion, even though it completely resolves on vigorous rubbing with alcohol swabs or water and soap (which provides both diagnosis and treatment).
This discoloration will disappear as the skin naturally renews itself and the top layer of skin is removed (typically takes a few days or at most a week). Ways of preventing skin discoloration are to wear latex or nitrile gloves to protect the hands and also by applying a thin layer of petroleum jelly or oil-based preparation around the hairline. Gentle abrasives such as moist baking soda or a small amount of toothpaste applied with a toothbrush may also help remove the uppermost layer of skin and dye (neither removes just the dye). Acetone and nail polish remover are not considered effective; laundry detergent may sometimes work as may moist cigarette ash rubbed into the stained area.
It is not recommended for use with benzoyl peroxide due to the risk of causing yellow- orange skin discoloration with this combination. Minocycline is an effective acne treatment, but it is not a first-line antibiotic due to a lack of evidence that it is better than other treatments, and concerns about its safety compared to other tetracyclines. Sarecycline is the most recent oral antibiotic developed specifically for the treatment of acne, and is FDA- approved for the treatment of moderate to severe inflammatory acne in patients nine years of age and older. It is a narrow-spectrum tetracycline antibiotic that exhibits the necessary antibacterial activity against pathogens related to acne vulgaris and a low propensity for inducing antibiotic resistance.

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