Sensitizing nursing home workers is not the only avenue to improvement.
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It's an amplified version of what travel already feels like: decentering, humbling, vividly sensitizing.
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Wahungu said the agency is sensitizing the judiciary to ensure smooth implementation of the ban.
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"Reality TV was sensitizing audiences to that aesthetic, 24-hour news as well," Mr. Myrick said.
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The Southeastern lone-star tick was exposing and thus sensitizing people to the sugar through its bites.
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Even more so, children "with sensitizing alleles on the dopamine receptor 2 and serotonin transporter genes" — a.k.a.
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"We are putting pressure and also sensitizing district collectors to punish the employers (of bonded laborers)," he said.
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As any retinol user can tell you, a multi-product hydrating regimen is essential in mitigating those skin-sensitizing effects.
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Research suggests adiponectin has anti-inflammatory and "insulin-sensitizing" properties and that may help reduce your risk for Type 2 diabetes.
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Initially Platts-Mills thought that maybe intestinal parasites or even a mold from the region was sensitizing patients to alpha-gal.
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Those mind-numbing exercises in high school—factoring polynomials, conjugating verbs, memorizing the periodic table—were possibly the opposite: mind-sensitizing.
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"We are promoting cooperation with content providers, sensitizing them as to content that violates Israeli law or the provider's terms of service," Shaked said.
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It seems that the low-salt guidelines could be 'priming' or 'sensitizing' our brains for an excessive reward from refined sugar and drugs of abuse.
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Steer clear of fragrances and essential oils during these months, and give your skin a rest from any chemical exfoliants or other strong, sensitizing acids.
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In much of this there was a familiar insinuation that parenthood is a singularly sensitizing, enlightening circumstance, giving someone a special stake in a more just world.
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That is why large Indian companies are rushing to change policies to include gender-neutral bathrooms, insurance for same-sex couples, leave for sex reassignment surgeries and sensitizing employees.
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He called for more LGBT-friendly policies such as gender neutral bathrooms, insurance for same-sex couples, leave for sex reassignment surgeries and sensitizing employees to make workplaces more inclusive.
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Use our heads and turn off all of the screaming on TV. It really seems to be just de-sensitizing us all, putting us into separate corners, and dumbing us the hell down.
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Baking soda is highly alkaline, and highly abrasive on the skin; it is also the key ingredient that gives most natural deodorants their sweat-absorbing, odor-fighting power, along with equally sensitizing essential oils.
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Peet Rivko, a fledgling "zero irritant" plant-based line, for example, eschews essential oils (along with nut oils, floral extracts and other sensitizing ingredients) in everything from the company's gentle cleanser to daily moisturizer.
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"The combination of these additives and finishes has an allergic and sensitizing effect on the human body, even if those several additives and finishes are relatively safe in their individual respective quantities," the lawsuit states.
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Despite justifiably high expectations of the laity that the abuse nightmare would finally be reined in, the focus was inexplicably modest, limited to sensitizing developing-world prelates to the suffering the scandal generates and best practices for responding.
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"With a one-time treatment with Revita DMR and without intensive lifestyle changes by the patient, we see an insulin-sensitizing effect and durable improvements in hepatic and glycemic indices over a year," Fractyl cofounder Harith Rajagopalan told TechCrunch.
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"The combination of these additives and finishes has an allergic and sensitizing effect on the human body, even if those several additives and finishes are relatively safe in their individual respective quantities," the Delta employees wrote in the lawsuit.
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"Environmental Communications's 'environmental photography' consisted of sensitizing oneself to the Los Angeles 'environment' to trace normally imperceptible environmental transformations and to penetrate an environmental resistance to imaging," curators Mark Wasiuta, Marcos Sánchez, and Adam Bandle told Hyperallergic in an email.
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But the mother, Tammy Weeks, was "not aware of the extent" of what Nicole was doing on social media, said Jarels, who is with the nonprofit group Help Save the Next Girl which focuses on sensitizing young women and girl to predators.
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Logistically, this required identifying and sensitizing communities, conducting baseline and endline assessment of all the children prior to tablet distribution, installing solar charging stations in all of these villages for the tablets, and physical data collection and tablet distribution by our heroic Field Assistants on motorbikes (just to name a few of the critical activities).
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This spring and summer, the public security minister, Gilad Erdan, traveled to London and to New York — where Hispanics make up about 222 percent of the Police Department, African-Americans 222 percent and Asians nearly 226 percent — to study those cities' experiences with diversifying and sensitizing their forces and with using body cameras to address complaints of police abuse.
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But how you stop this then gets to the prophylactic measures, which would be to harden voting procedures, harden them from meddling, sensitizing officials for signs of meddling, and measures that they should take at the local, regional, and state levels to assure the integrity of the electoral process What one does with respect to disinformation, this has always existed, but with new technologies it's exponentially more effective to do and harder to counter.
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There is no absolute conformity in the sensitizing potential of a substance in mouse, guinea pig and human.
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In the periphery, TrkB/BDNF binding and TrkB/NT-4 binding acutely sensitizing nocireceptive pathway that require the presence of mast cells.
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In panchromatic emulsions, the sensitivity of the silver halide crystal is enhanced by sensitizing dyes that adsorb on the crystal surface. Therefore, sensitivity can be increased by adsorbing more sensitizing dye. This requires increasing the surface area of the crystal, and also improving the dye molecules to form a dense assembly. Tabular grain emulsion solves the first part of this problem.
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The dust created from sanding rosewood is known to be a sensitizing irritant and can trigger asthma and other respiratory ailments. Continual or heightened exposure can increase sensitivity.
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Plasma leaks out into the connective tissues, and they swell. The process also loses pro- inflammatory cytokines. Pain—The cytokines increase COX-2 activity. This elevates levels of PGE2, sensitizing pain neurons.
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Evidence was emerging in 2008 that vitamin E with thiazolidinediones is effective in the treatment of non-alcoholic steatohepatitis due to their combined antioxidant and insulin sensitizing effects, producing histological improvements in steatosis severity.
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An HMW glutelin (glutenin) of the grass tribe Triticeae has been implicated as a sensitizing agent for coeliac disease in individuals possessing the HLA-DQ8 class II antigen receptor gene. This tribe contains wheat and oats.
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Thus, for overweight women with anovulation and PCOS, lifestyle modifications are important, and are very often an integral part of the treatment plan to relieve PCOS symptoms. These lifestyle modifications may include increased exercise and a diverse diet composed of fruits, vegetables, low-fat products, and lean meats. Following weight loss are insulin-sensitizing drugs. This class of drugs is the main therapy for women who experience irregular cycles, and want to improve their fertility. One example of an insulin-sensitizing drug is Metformin, which works by inhibiting the liver’s production of glucose.
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However, once the infant is delivered, the immature system is not able to handle this amount of bilirubin alone and jaundice or kernicterus (bilirubin deposition in the brain) can develop which may lead to brain damage or death. Sensitizing events during pregnancy include c-section, miscarriage, therapeutic abortion, amniocentesis, ectopic pregnancy, abdominal trauma and external cephalic version. However, in many cases there was no apparent sensitizing event. Approximately 50% of Rh-D positive infants with circulating anti-D are either unaffected or only mildly affected requiring no treatment at all and only monitoring.
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The ratio of tracer incorporation in lymph nodes from dosed animals is compared to control animals, giving a stimulation index (SI). When the stimulation index exceeds 3 (SI > 3), a relevant sensitizing potential is assumed. In contrast to the classical guinea pig tests, the LLNA provides a quantitative measurement of sensitizing potency of a tested chemical. The LLNA may not be appropriate for certain metallic compounds, surfactants, high-molecular-weight proteins, strong dermal irritants, and materials that do not sufficiently adhere to the ear for an acceptable period of time during treatment.
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Set up for holographic recording For two-color holographic recording, the reference and signal beam fixed to a particular wavelength (green, red or IR) and the sensitizing/gating beam is a separate, shorter wavelength (blue or UV). The sensitizing/gating beam is used to sensitize the material before and during the recording process, while the information is recorded in the crystal via the reference and signal beams. It is shone intermittently on the crystal during the recording process for measuring the diffracted beam intensity. Readout is achieved by illumination with the reference beam alone.
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Instead, they saw corticolimbic circuitry (implicated in emotion and memory) had a bigger role in HDACi related alterations of reward behaviors. Evidence that HDACi-mediated enhancement of a stimulant's sensitizing effects is context specific, and involves associative learning.
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Standards assess products for the presence of allergenic dyes and sensitizing chemicals“Chemical Allergens-What Are the Issues?”. Kimber, Ian, David A. Basketter, and Rebecca J. Dearman. 2010. “Chemical Allergens-What Are the Issues?” Toxicology 268(3): 139–42.
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Spirotetramat has moderate to low acute toxicity, is irritating to eyes and potentially sensitizing to skin. When tested on rats, it was not shown to be carcinogenic. In Denmark, it is listed as harmful to aquatic invertebrates, but not dangerous to bees.
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Activation of KORs on peripheral nerve terminals results in the inhibition of ion channels responsible for afferent nerve activity, causing reduced transmission of pain signals, while activation of KORs expressed by immune system cells results in reduced release of proinflammatory, nerve-sensitizing mediators (e.g., prostaglandins).
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For awareness, a team of experts will conduct workshops for sensitizing the main parties including builders and activists. The government will establish a special university for differently-abled people with a corpus of which will start functioning from the next academic year with special courses.
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The ester derivative are being investigated as a nitric oxide donors in biology and medicine. Due to the relatively low toxicity and good stability Roussin’s red salt. Photolysis of the compound induces the release of NO, thereby sensitizing target cells to exposure to radiation [2].
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It confirmed that crude balsam of Peru should not be used as a fragrance ingredient, because of a wide variety of test results on its sensitizing potential, but that extracts and distillates can be used up to a maximum level of 0.4% in products.
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Oil of guaiac is primarily composed of 42–72% guaiol, bulnesol, δ-bulnesene, β-bulnesene, α-guaiene, guaioxide and β-patchoulene. It is considered non- irritating, non-sensitizing, and non phototoxic to human skin. Oil of guaiac was also a pre-Renaissance remedy to syphilis.
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Named after former board member Arthur Ashe, the Arthur R. Ashe Foreign Policy Library is the only library in the U.S. dedicated to sensitizing Americans about African, Caribbean, and Latin-American issues. It is an important resource for policy analysts, scholars and the public.
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Decreased vision due to vitreous inflammation may occur. Unlike MEWDS, MPC is a chronic disorder and macular scarring contributes to severe visual loss. Theories regarding the cause include an exogenous pathogen sensitizing an individual to antigens within photoreceptors, RPE, or choroid.Polk TD, Goldman EJ. Chorioretinal Inflammatory Syndromes.
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Professionally trained beekeeper, Ludovic Belleval, produces flower honey, propolis, royal jelly, and pollen. In June and July, he welcomes classes to witness the harvesting of the flowing frames of honey. Belleval is an educator-beekeeper and aims at sensitizing school-children to the importance of Environmental issues.
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MWA works together with other non-profit groups in order to engage the government of Malawi for the realization of Dual Citizenship for Malawians in the Diaspora. MWA's initiative, Movement for Dual Citizenship for Malawi, aims at sensitizing Malawians about matters concerning dual citizenship in Malawi.
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Adavosertib (development codes AZD1775, MK-1775) is an experimental anti- cancer drug candidate. It is a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. It is being developed by AstraZeneca.It is being investigated as a treatment for pancreatic cancer with phase 1 trial.
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"The works applying concepts from the logical framework of structuration theory that Giddens approved of were those that used them more selectively, 'in a spare and critical fashion.'" Giddens and followers used structuration theory more as "a sensitizing device".Turner, J.H. (1986). Review essay: The theory of structuration.
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The progression to cirrhosis may be influenced by the amount of fat and degree of steatohepatitis and by a variety of other sensitizing factors. In alcoholic FLD, the transition to cirrhosis related to continued alcohol consumption is well- documented, but the process involved in non-alcoholic FLD is less clear.
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Rhesus Solution Initiative (also known as RSI) is a non-governmental organization in Nigeria that focuses on sensitizing the society, particularly teenagers and pregnant women on the importance of knowing their blood group and rhesus status to prevent problems associated with rhesus disease and provide access to anti D immunoglobulin.
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The program aims to holistically impact a girl child's education, health, and nutrition while sensitizing their families on their welfare. In the 1st phase of the program, he has selected of 4 schools from 4 blocks respectively. Through these schools the impact will be on more than 1000 girls and their families.
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Activation of these receptors amplifies gene expression and, in doing so, may be the mechanistic base of triclocarban's health impact on humans. However, further investigation is needed to determine whether triclocarban increases the activity of sex steroid hormones by binding to the receptors or by binding to and sensitizing the receptor coactivators.
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In India, the Indian Society for Trenchless Technology or IndSTT is the apex organization to promote trenchless technology in South Asia. It was established in 1995 with its head office at New Delhi. No Dig India is the official Journal of IndSTT. Several organizations bring out technical Journals for sensitizing the readers about such techniques.
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Most sensitizing pro-inflammatory agents activate the phospholipase C pathway. Phosphorylation of TRPV1 by protein kinase C have been shown to play a role in sensitization of TRPV1. The cleavage of PIP2 by PLC-beta can result in disinhibition of TRPV1 and, as a consequence, contribute to the sensitivity of TRPV1 to noxious stimuli.
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This initiative was endorsed by the Lagos State Ministry Of Women Affairs and Poverty Alleviation. This campaign led to her organization organizing rape sensitizing workshops in secondary schools across the Nigeria tagged College Acquaintance Rape Education (C.A.R.E), in partnership with the Lagos state Ministry of Justice and the Domestic and Sexual Violence Response Team (DSVRT).
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Sedona, BEST Life Media. Lee categorizes all of his training techniques under one or more of the five sequential steps that comprise Brain Education. The focus of each step is as follows: # Brain Sensitizing: Stress management, awakening of the five senses, physical health, and brain awareness. # Brain Versatilizing: Enhanced learning ability through the creation of new synaptic connections.
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Page 160. . Characteristically the lesions appear in sun-exposed areas such as the vee of the neckline or the forearms, but not the face. It may be brought on by sun-sensitizing medications, but is usually associated with autoimmune disorders such as rheumatoid arthritis and Sjögren's syndrome. Treatment generally involves sun avoidance and protection and topical corticosteroids.
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Program Name: Inclusive Education in Northern Uganda Partner: Leonard Cheshire Disability (LCD) Program Description: The program aims to improve the life chances for children with disabilities through inclusive primary education, by ensuring the enrollment of 500 children with disabilities in mainstream schools in Amolatar district, and supporting them with the interventions necessary to improve their learning. The program works on sensitizing and training teachers on Inclusive Education and teaching techniques, and sensitizing communities, school management committees and parent teacher association on the right to quality education of children living with disability. It provides locally-sourced assistive devices to schools and students, and supports the adaptation of school infrastructure to meet the needs of the students. The program established an Inclusive Education Resource Centre in Amolator town to serve all teachers and students in the district.
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She takes part in the program "Eat well, it's well played!" launched in 2005 by the Sports Foundation. She is also involved in the production of videos aimed at young athletes to teach them the basics of a diet adapted to physical effort, as part of a program of the Sports Foundation sensitizing children to the importance of the sport. physical activity.
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G-protein coupled receptor 120 is a protein that in humans is encoded by the GPR120 gene. GPR120 is a member of the rhodopsin family of G protein-coupled receptors (GPRs). GPR120 has also been shown to mediate the anti-inflammatory and insulin-sensitizing effects of omega 3 fatty acids. Lack of GPR120 is responsible for reduced fat metabolism, thereby leading to obesity.
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It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis.
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PDT has the most supporting evidence of all light therapy modalities. When regular light is used immediately following the application of a sensitizing substance to the skin such as aminolevulinic acid or methyl aminolevulinate, the treatment is referred to as photodynamic therapy (PDT). PDT treats acne by using various forms of light (e.g., blue light or red light) that preferentially target the pilosebaceous unit.
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This allows for the speedy and accurate detection of a single finger, but it causes some ambiguity if more than one finger is to be detected. Two fingers may have four possible detection positions, only two of which are true. However, by selectively de-sensitizing any touch-points in contention, conflicting results are easily eliminated. This enables "Self Capacitance" to be used for multi-touch operation.
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The author of Viagra and vision attributes cyanopsia after taking sildenafil to diminished enzyme activity, thereby sensitizing the retinal rod cells. Rod cells are most sensitive to light of wavelengths near 498 nm; such light appears blue-green. When light levels are low enough for both rods and cone cells to be active (mesopic vision) the enhanced rod activity induces the bluish visual tint.
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Hyperalgesia ( or ; 'hyper' from Greek ὑπέρ (huper, “over”), '-algesia' from Greek algos, ἄλγος (pain)) is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus. Prostaglandins E and F are largely responsible for sensitizing the nociceptors. Temporary increased sensitivity to pain also occurs as part of sickness behavior, the evolved response to infection.
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He worked as a lecturer at Nkumba University and also volunteered at Interreligious Council of Uganda. He was working with Urban TV Uganda be he joined NBS Televion in 2016. He was also part of Topowa Campaign by CCEDU, a human Rights advocate team sensitizing people during the 2016 general elections. He was of recent arrested for allegedly undermining government put meaures to cub the spread of COVID-19.
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The specific inhalation challenge (SIC) is a diagnosis tool to assess airway responsiveness to "sensitizing" substances as opposed to nonspecific stimuli such as pharmacological agents (i.e. histamine, methacholine), cold air and exercise. Subjects are exposed to a suspected occupational agent in a controlled way under close supervision in a hospital laboratory. The specific inhalation challenges has been considered as the gold standard in confirming the diagnosis of occupational asthma.
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Through these protests, the Greens provide a public reaction to environmental degradation and pollution as a means of sensitizing the public to the ongoing issues. In addition to protests, The Green Party has undertaken a series of concrete actions for public awareness, such as seminars, workshops, environmental conferences, distribution of posters, leaflets, territory cleaning activities, and waste reduction. The party's activities have found wide support throughout different segments of the population.
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Board members stand in front of their 'thrift cooperative' in Mulukanoor, Andhra Pradesh. A. Nippierd argues that on a more micro or local level, sensitizing managers and leaders of cooperatives to gender issues is a key starting point towards increasing gender equality. It is only with a full understanding of the issues and a strong decision to methodically address them that proactive measures begin to be enforced.Nippierd, A. (2002).
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By then, chemists from other universities and industry were also contributing. One example of much needed chemicals were dyes for sensitizing photographic film. Research efforts in this field led to the foundation of Eastman Kodak Organic Chemicals Division. The summer preps contributed to the war effort in World War II but were discontinued in 1950 because by then an infrastructure of chemical companies with their own research had been established.
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Gender Sensitization and Education. International Journal of Interdisciplinary and Multidisciplinary Studies (IJIMS), 2(4), 107-113. Teachers who are successful at sensitizing their students to gender at a young age can influence a change in children's thought processes, which positions them to break societal stigmas in childhood and throughout life. Teaching children to be sensitive to gender also relies heavily on the parents or guardians of the children.
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Visible, irritating bites are due to an immune response from the binding of IgG and IgE antibodies to antigens in the mosquito's saliva. Some of the sensitizing antigens are common to all mosquito species, whereas others are specific to certain species. There are both immediate hypersensitivity reactions (types I and III) and delayed hypersensitivity reactions (type IV) to mosquito bites. Both reactions result in itching, redness and swelling.
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Despite the recent dramatic decrease of social hostility and discrimination in the U.S. Army as a result of the EO Program, many individuals still find ways to criticize it. The primary argument consists of the possible side effects of "over-sensitizing" the armed forces. The U.S. Army operates in a male-dominant environment where extreme aggression is praised. Teaching soldiers to be compassionate of others feelings and insecurities can appear to some soldiers as counterproductive.
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Darglitazone (previously known as CP 86325-2) is a member of the class of drugs and an agonist of peroxisome proliferator-activated receptor-γ (PPAR-γ), an orphan member of the nuclear receptor superfamily of transcription factors. It has a variety of insulin-sensitizing effects, such as improving glycemic and lipidemic control, and was researched by Pfizer as a treatment of metabolic disorders such as . Its development was terminated on November 08, 1999.
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Hemolytic disease of the fetus and newborn (HDN) is a condition where the passage of maternal antibodies results in the hemolysis of fetal/neonatal red cells. The antibodies can be naturally occurring such as anti-A, and anti-B, or immune antibodies developed following a sensitizing event. Isoimmunization occurs when the maternal immune system is sensitized to red blood cell surface antigens. The most common causes of isoimmunization are blood transfusion, and fetal-maternal hemorrhage.
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Hemolytic disease of the fetus and newborn (HDN) is a condition where the passage of maternal antibodies results in the hemolysis of fetal/neonatal red cells. The antibodies can be naturally occurring such as anti-A, and anti-B, or immune antibodies developed following a sensitizing event. Isoimmunization occurs when the maternal immune system is sensitized to red blood cell surface antigens. The most common causes of isoimmunization are blood transfusion, and fetal-maternal hemorrhage.
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Technical Pan is a microfilm emulsion that was made panchromatic through the addition of sensitizing dyes, as is the case with all panchromatic films. If developed in a general-purpose developer such as D-76, Tech Pan displays extreme contrast. It becomes a pictorial film when developed in a very low-contrast developer. The film can be developed at home, mainly by using the chemical mixture Technidol, which Kodak sold for that purpose alone.
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Cancer is the uncontrolled growth of cells with loss of differentiation and commonly with metastasis. Anticancer drugs are used to control the growth of cancerous cells. Oxaliplatin is a third-generation platinum-derived antineoplastic agent that has been proved effective mainly against advanced colorectal cancer (CRC). Oxaliplatin administration has an acute excitatory and sensitizing effect, including unpleasant cold allodynia in the distal extremities, mouth, and throat and usually associated with muscle cramps.
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Kalpavriksha, the social b-plan contest of Ahvan, is one of the most prestigious business plan events across the country. It was conceptualized in 2006 with the focus on sensitizing the participants about their responsibility and the potential difference they can make. It provides a platform for budding entrepreneurs to showcase self-sustainable B-plans with a strong societal focus. The event has been associated with reputed sponsors like Infosys, Tata Group, Deloitte and Cognizant.
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Over the years, PHR-I has built partnerships with other local non-governmental, independent organizations. Through consistent collaborative work, the mobile clinic aims to serve as a gesture of trust and solidarity with Palestinian patients and medical professionals, help to foster greater recognition for human rights values among the Israeli medical community, while sensitizing the Israeli public and international community to the need for Israeli policy change vis- à-vis the occupied Palestinian territory.
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Alternatively, ambiguity can be avoided by applying a "de-sensitizing" signal to all but one of the columns . This leaves just a short section of any row sensitive to touch. By selecting a sequence of these sections along the row, it is possible to determine the accurate position of multiple fingers along that row. This process can then be repeated for all the other rows until the whole screen has been scanned.
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Hemolytic disease of the fetus and newborn (HDN) is a condition where the passage of maternal antibodies results in the hemolysis of fetal/neonatal red cells. The antibodies can be naturally occurring such as anti-A, and anti-B, or immune antibodies developed following a sensitizing event. Isoimmunization occurs when the maternal immune system is sensitized to red blood cell surface antigens. The most common causes of isoimmunization are blood transfusion, and fetal-maternal hemorrhage.
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ANHAD's activities include secular mobilization, sensitizing people about their democratic rights as enshrined in Indian Constitution, research and publication of books and reports, welfare programs for marginalised sections of society, launching creative mass mobilization campaigns. People's tribunals. It also work as a pressure group among political circle to take action against communalism. ANHAD plays a major role in Gujarat to fight against human right violations, as well as in the Kashmir Valley.
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This campaign led to her organization organizing rape sensitizing workshops in secondary schools across the Nigeria tagged College Acquaintance Rape Education (C.A.R.E), in partnership with the Lagos state Ministry of Justice and the Domestic and Sexual Violence Response Team (DSVRT).Speaking about the separation in The Sun ( Nigeria) newspaper, Esther encouraged her fellow women facing domestic violence to re-consider their long term position in such relationship to salvage their sanity and life.
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Phytophotodermatitis, also known as berloque dermatitis or margarita photodermatitis, is a cutaneous phototoxic inflammatory reaction resulting from contact with a light-sensitizing botanical agent followed by exposure to ultraviolet light (from the sun, for instance). Symptoms include erythema, edema, blisters (vesicles and/or bullae), and delayed hyperpigmentation. Heat and moisture tend to exacerbate the reaction. A reaction may be elicited in any person who has been exposed to adequate amounts of both a photosensitizing agent and ultraviolet light.
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Robert Gover (November 2, 1929 – January 12, 2015) was an American journalist who became a best-selling novelist at age 30. His first novel, One Hundred Dollar Misunderstanding, a satire on American racism, remains a cult classic that helped break down America's fear of four-letter words and sexually explicit scenes, as well as sensitizing Americans to sanctimonious hypocrisy. Gover worked with writers for three decades. On the Run with Dick and Jane was his ninth novel.
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The only part left of Fischer's original problem with a multi-layer emulsion were the wandering sensitizing dyes. In 1929 money ran out, and Mees decided to help them once more. Mees knew that the solution to the problem of the wandering dyes had already been found by one of Kodak's own scientists, Leslie Brooker. So he gave Mannes and Godowsky enough money to pay off the loan Kuhn Loeb had supplied and offered them a yearly salary.
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At this temperature, nitroglycerin freezes, contracting upon solidification. Thawing it out can be extremely sensitizing, especially if impurities are present or the warming is too rapid. Chemically "desensitizing" nitroglycerin is possible to a point where it can be considered about as "safe" as modern high explosives, such as by the addition of roughly 10 to 30% ethanol, acetone, or dinitrotoluene (the percentage varies with the desensitizing agent used). Desensitization requires extra effort to reconstitute the "pure" product.
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By similar techniques, special-purpose films can be made sensitive to the infrared (IR) region of the spectrum. In black-and-white photographic film, there is usually one layer of silver halide crystals. When the exposed silver halide grains are developed, the silver halide crystals are converted to metallic silver, which blocks light and appears as the black part of the film negative. Color film has at least three sensitive layers, incorporating different combinations of sensitizing dyes.
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Low PPAR-gamma reduces the capacity of adipose tissue to store fat, resulting in increased storage of fat in nonadipose tissue (lipotoxicity). A soy protein diet increases adipose tissue PPAR-gamma, thereby reducing lipotoxicity. Many insulin sensitizing drugs (namely, the thiazolidinediones) used in the treatment of diabetes activate PPARG as a means to lower serum glucose without increasing pancreatic insulin secretion. Activation of PPARG is more effective for skeletal muscle insulin resistance than for insulin resistance of the liver.
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This may renormalize tobacco use in the general public. There is a possible risk of re-normalizing of tobacco use in areas where smoking is banned. Government intervention is recommended to keep children safe from the re-normalizing of tobacco, according to a 2017 review. The "catalyst model" suggests that vaping may proliferate smoking in minors by sensitizing minors to nicotine with the use of a type of nicotine that is more pleasing and without the negative attributes of regular cigarettes.
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Tarimo served as a director of Lindi Regional Centre, a satellite branch of the Open University of Tanzania, from 2007 to 2013. During her tenure, enrollment at the centre grew significantly and, by 2013, 50 students from the centre had graduated and more than 200 were continuing with their studies. She left her mark in Lindi by sensitizing higher education in the region. While serving as director, she initiated a fundraising campaign that enabled the centre to purchase its own vehicle.
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It also has an insulin-sensitizing effect with multiple actions on tissues including the liver, skeletal muscle, endothelium, adipose tissue, and the ovary. The average patient with type 2 diabetes has three times the normal rate of gluconeogenesis; metformin treatment reduces this by over one-third. Activation of AMPK was required for metformin's inhibitory effect on liver glucose production. AMPK is an enzyme that plays an important role in insulin signalling, whole-body energy balance and the metabolism of glucose and fats.
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Threshold Pharmaceuticals discontinued the hypoxia activated prodrug, TH-302, after Phase III trials failed to show statistically significant overall survival. Niacinamide, the active form of vitamin B3, acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. Niacinamide also inhibits poly(ADP-ribose) polymerases (PARP-1), enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy. As of August 2016, no clinical trials appear to be in progress for this indication.
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Celastrol (tripterine) is a chemical compound isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In mice, celastrol increase expression of IL1R1, which is the receptor for the cytokine interleukin-1 (IL-1). This suggests that celastrol exhibits its anti- obesity effects via a pro-inflammatory signaling pathway, as IL1R1 knock-out mice exposed to celastrol exhibit no leptin-sensitizing or anti-obesity effect.
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As Chair of the UN ESCAP Economic Business Council's Task Force on MSMEs and Entrepreneurship for Development in Asia and the Pacific, Narain conducts the Young Business Leaders Programme. This program is designed for sensitizing entrepreneurs, banks, and DFIs to the ethical principles of Socially Responsible Business and Investments. Narain has designed and implemented several credit-based financial schemes and non-financial support services for assisting MSMEs, as well as risk mitigation-collateral-free SME credit guarantee schemes for banks and DFIs.
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Post-operatively, local areas of numbness (paresthesia) might occur in the contoured portion(s) of the gluteal region, and might perdure for a long time after the surgery. Hence, the patient is advised to facilitate the re-sensitizing of the numb area(s) with applications of gentle massage, to prevent the development of a neuroma complication, and to alleviate pain. Nonetheless, depending upon the tissue-healing capabilities of the patient, he or she can recover in full at 2-years post-operative.
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Relative to other NSAIDs, salsalate has a weak inhibitory effect on the cyclooxygenase enzyme and decreases the production of several proinflammatory chemical signals such as interleukin-6, TNF-alpha, and C-reactive protein. The mechanism through which salsalate is thought to reduce the production of these inflammatory chemical signals is through the inhibition of IκB kinase resulting in decreased action of NF-κB genes. This mechanism is thought to be responsible for salsalate's insulin-sensitizing and blood sugar lowering properties.
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The collodion wet plate process that gradually replaced the daguerreotype during the 1850s required photographers to coat and sensitize thin glass or iron plates shortly before use and expose them in the camera while still wet. Early wet plate cameras were very simple and little different from Daguerreotype cameras, but more sophisticated designs eventually appeared. The Dubroni of 1864 allowed the sensitizing and developing of the plates to be carried out inside the camera itself rather than in a separate darkroom.
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Unmodified silver halide crystals are sensitive only to the blue part of the visible spectrum, producing unnatural-looking renditions of some colored subjects. This problem was resolved with the discovery that certain dyes, called sensitizing dyes, when adsorbed onto the silver halide crystals made them respond to other colors as well. First orthochromatic (sensitive to blue and green) and finally panchromatic (sensitive to all visible colors) films were developed. Panchromatic film renders all colors in shades of gray approximately matching their subjective brightness.
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This oil is a pale yellow liquid and contains up to 60% 1,8-cineole, the main antimicrobial component of the oil . Cajuput oil has been classified as non-toxic and non- sensitizing, although skin irritation may occur at high concentrations. It has been reported to be useful as an insect repellant, as a sedative and relaxant and is useful in treating roundworms and urino-genital infections. It is used to flavour foods and to add to the fragrance of soaps and cosmetics.
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Clinical trials of TSC have focused on testing the compound's effectiveness in sensitizing hypoxic cancer cells to radiation therapy in patients with glioblastoma, an aggressive form of brain cancer. TSC, which is being developed by Diffusion Pharmaceuticals, has been shown to enhance the oxygenation of hypoxic tumor tissue and belongs to a subclass of oxygen diffusion-enhancing compounds known as bipolar trans carotenoid salts. Diffusion Pharmaceuticals is currently investigating the use of trans sodium crocetinate in the treatment of COVID-19, acute stroke, and solid cancerous tumors.
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During research and development, pramocaine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent. Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans. Like other local anesthetics, pramocaine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
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However, some prewarnings can work paradoxically to increase memory conformity by overly sensitizing the initial viewer, who then mistakenly incorporates incorrect post-event information into their initial memory. Postwarnings are post-event attempts to reduce conformity. The misinformation effect can occur when the memory of an eyewitness is influenced by misinforming him or her after an event. Studies have found that social "postwarnings," like characterizing an individual as having low credibility after the misinformation has been introduced, can reduce the misinformation or memory conformity effect.
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The military lacked the capacity to demobilize armed groups or adequately prevent the trafficking violations committed by members of its own forces. The country's criminal and military justice systems, including the police, courts, and prisons were practically nonexistent; there were few functioning courts or secure prisons in the country. Some advances, however, were noted during the reporting period in demobilizing children from fighting factions, including from the national army, and in sensitizing military officials about the illegality of committing forced labor abuses."Democratic Republic of the Congo".
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Additionally, the UPS also plays a role in inflammatory responses as regulators of leukocyte proliferation, mainly through proteolysis of cyclines and the degradation of CDK inhibitors. Lastly, autoimmune disease patients with SLE, Sjögren syndrome and rheumatoid arthritis (RA) predominantly exhibit circulating proteasomes which can be applied as clinical biomarkers. Radiation therapy is a critical modality in the treatment of cancer. Accordingly, the proteasome subunit alpha type-1 was examined as a strategy in radio sensitizing for the treatment of non-small-cell lung carcinomas.
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Additionally, the UPS also plays a role in inflammatory responses as regulators of leukocyte proliferation, mainly through proteolysis of cyclines and the degradation of CDK inhibitors. Lastly, autoimmune disease patients with SLE, Sjögren syndrome and rheumatoid arthritis (RA) predominantly exhibit circulating proteasomes which can be applied as clinical biomarkers. Radiation therapy is a critical modality in the treatment of cancer. Accordingly, the proteasome subunit alpha type-1 was examined as a strategy in radio sensitizing for the treatment of non-small cell lung carcinomas.
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Addiction is a brain disorder characterized by compulsive drug use despite adverse consequences. Addiction is a component of a substance use disorder and represents the most severe form of the disorder. Overexpression of the gene transcription factor ΔFosB in the nucleus accumbens plays a crucial role in the development of an addiction to opioids and other addictive drugs by sensitizing drug reward and amplifying compulsive drug-seeking behavior. Like other addictive drugs, overuse of opioids leads to increased ΔFosB expression in the nucleus accumbens.
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It is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted in urine without accumulating in the body. Acute toxicity studies have shown that methylparaben is practically non-toxic by both oral and parenteral administration in animals. In a population with normal skin, methylparaben is practically non-irritating and non-sensitizing; however, allergic reactions to ingested parabens have been reported. A 2008 study found no competitive binding for human estrogen and androgen receptors for methylparaben, but varying levels of competitive binding were seen with butyl- and isobutyl- paraben.
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The most common cause of hyperacusis is overexposure to excessively high decibel (sound pressure) levels. Some sufferers acquire hyperacusis suddenly as a result of taking ear sensitizing drugs, Lyme disease, Ménière's disease, head injury, or surgery. Others are born with sound sensitivity, develop superior canal dehiscence syndrome, have had a history of ear infections, or come from a family that has had hearing problems. Bell's palsy can trigger hyperacusis if the associated flaccid paralysis affects the tensor tympani, and stapedius, two small muscles of the middle ear.
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This is world’s one of such project which focuses on empowering children by sensitizing all stakeholders including parents, teachers, law enforcement, local government officials and elected public representatives.Child-Friendly Constituency: Kalinga Kusum does capacity development in Khandapada, Odisha Under the project, 126 children, and adolescent collectives have been formed in 40 panchayats and one urban local body of the Khandapada Assembly constituency. 40 GPRPs have been trained to create child clubs, disseminate information and train parents in child rights. These have become catalysts to ensure facilitation of child rights.
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At this junction, DCC is not a pharmaceutical target. As DCC is not overexpressed in cancer and is present throughout the body, so it is not considered a good target for most types of cancer drugs. DCC is expressed at very low levels through most of the body but at higher levels in many areas of the brain, particularly in dopamine neurons. Recently it has been shown that a sensitizing treatment regimen of amphetamines causes markedly increased levels of DCC and UNC-5 expression on neuron cell bodies.
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There were also some members in the Compton city government who disagreed with the chief's methods. “I will never be a hard core law and order man,” he insisted, “nor will I stand for the type of law enforcement that title has come to represent in recent years. I’m trying to enforce justice in the city while, at the same time, sensitizing the people in Compton to the underlying reasons for crime.” “The way I perceive the police chief’s job,” continued the chief, “is that he is the man in the middle.
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All RhD negative pregnant women should receive RhoGam at 28 weeks gestation and within 72 hours after childbirth in addition to doses with any sensitizing event (miscarriage, trauma, bleeding). Most RhD mediated disease can be prevented if this is done. There are theories as to why or how this works, but none have been proven definitively to be the case. In addition, there has been research into finding a non-human derived version of this antibody, but none have been as effective as the currently available human derived formulations.
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Although it would be many more years before these sensitizers (and better ones developed later) found much use beyond scientific applications such as spectrography, they were quickly and eagerly adopted by Louis Ducos du Hauron, Charles Cros and other color photography pioneers. Exposure times for the "problem" colors could now be reduced from hours to minutes. As ever-more-sensitive gelatin emulsions replaced the old wet and dry collodion processes, the minutes became seconds. New sensitizing dyes introduced early in the 20th century eventually made so- called "instantaneous" color exposures possible.
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Once the light activates the sensitizing substance, this generates free radicals and reactive oxygen species in the skin, which purposefully damage the sebaceous glands and kill C. acnes bacteria. Many different types of nonablative lasers (i.e., lasers that do not vaporize the top layer of the skin but rather induce a physiologic response in the skin from the light) have been used to treat acne, including those that use infrared wavelengths of light. Ablative lasers (such as CO2 and fractional types) have also been used to treat active acne and its scars.
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More recently, based on recent findings showing that by-product formation most likely occurs exclusively from the lowest singlet excited state,D. Mendive-Tapia, A. Perrier, M. J. Bearpark, M. A. Robb, B. Lasorne, D. Jacquemin, Phys. Chem. Chem. Phys. 16:18463-18471 (2014) M. Herder, B. Schmidt, L. Grubert, M. Pätzel, J. Schwarz, S. Hecht, J. Am. Chem. Soc. 137 (7):2738–2747 (2015) a superior fatigue resistance of dithienylethenes upon visible-light excitation has been achieved by attaching small triplet- sensitizing moieties to the diarylethene core via a -conjugated linkage.
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A fault is said to be detected by a test pattern if the output of that test pattern, when testing a device that has only that one fault, is different than the expected output. The ATPG process for a targeted fault consists of two phases: fault activation and fault propagation. Fault activation establishes a signal value at the fault model site that is opposite of the value produced by the fault model. Fault propagation moves the resulting signal value, or fault effect, forward by sensitizing a path from the fault site to a primary output.
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Neroli (Citrus aurantium) essential oil in a clear glass vial It is one of the most widely used floral oils in perfumery. Like all essential oils neroli is irritating, sensitizing and a known allergen because of the high content of aromatic terpenes such as linalool, limonene, farnesol, geraniol and citral. It blends well with any citrus oil, various floral absolutes, and most of the synthetic components available on the market. Neroli oil is a classic element in fragrance design and one of the most commonly used in the industry.
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Harekrushna Mahatab's role in this success has become cherished in Bhadrak, and a part of the history of modern India. Gandhi, who visited Bhadrak again in 1934, staying in Mahatab's residence at Nuabazar, addressed a meeting of the Harizan workers in Jimbaran Ashram (Nuasahi, Ashram, Garadpur). It was during this time that Banchhanidhi Mohanty of Eram was by his patriotic songs shaping, stimulating, and sensitizing the national consciousness among the people. Since independence, the history of Bhadrak has been of progress in education, industry, agriculture, trade, and commerce.
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Most studies show no benefit from the addition of chemotherapy. However, a large clinical trial of 575 participants randomized to standard radiation versus radiation plus temozolomide chemotherapy showed that the group receiving temozolomide survived a median of 14.6 months as opposed to 12.1 months for the group receiving radiation alone. This treatment regimen is now standard for most cases of glioblastoma where the person is not enrolled in a clinical trial. Temozolomide seems to work by sensitizing the tumor cells to radiation, and appears more effective for tumors with MGMT promoter methylation.
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Hence the readout beam with a longer wavelength would not be able to excite the recombined electrons from the deep trap centers during readout, as they need the sensitizing light with shorter wavelength to erase them. Usually, for two-color holographic recording, two different dopants are required to promote trap centers, which belong to transition metal and rare earth elements and are sensitive to certain wavelengths. By using two dopants, more trap centers would be created in the lithium niobate crystal. Namely a shallow and a deep trap would be created.
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Sensitization refers to the precipitation of carbides at grain boundaries in a stainless steel or alloy, causing the steel or alloy to be susceptible to intergranular corrosion or intergranular stress corrosion cracking. Unsensitized microstructure Heavily sensitized microstructure Certain alloys when exposed to a temperature characterized as a sensitizing temperature become particularly susceptible to intergranular corrosion. In a corrosive atmosphere, the grain interfaces of these sensitized alloys become very reactive and intergranular corrosion results. This is characterized by a localized attack at and adjacent to grain boundaries with relatively little corrosion of the grains themselves.
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"We are not doing this to make money, we are interested in developing a compound that would be a benefit to society," he explained. The effort to make Zerit more affordable was a success: millions of people around the world benefited from Prusoff's research and humanitarian efforts. Though William Prusoff officially retired at age 70, he never stopped working and continued to be industrious. Until his death, his work as professor emeritus concentrated on the potential for using boronated-thymidine analogs as sensitizing cancer agents for neutron therapy.
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There were a number of technical issues with the system, including the relatively long time required to make each sequence of three exposures and the difficulty of correctly balancing them to obtain accurate color values under different lighting conditions. In 1901, Miethe had introduced "Ethyl Red", a sensitizing dye that greatly improved the characteristics of panchromatically sensitized photographic emulsions, which in turn obviated the very long exposures previously needed to photograph red-filtered images, simplified color filter design, and generally cleared the path for future progress."Frühe Farbfotografie: Bunt fürs Leben". In Spiegel Online.
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TransAfrica was a founding member of the Free South Africa Movement. It is a grassroots organization that laid the foundation for the taking the anti-apartheid movement in the U.S. to mainstream politics and lobbying for change. They were at the forefront of the sensitizing U.S. policy makers, students and the public about the anti-apartheid efforts in a strategic move. On November 21, 1984, a day before Thanksgiving, Randall Robinson, Congressman Walter Fauntroy and Mary Frances Berry were arrested for a sit-in staged at the South African embassy.
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Mendell's research within neurotrophins has focused specifically on nerve growth factors (NGF) and their role that they play within inflammatory pain. Within this, there was also a focus in brain-derived neurotrophic factor (BDNF) and their sensitizing effect on specific synaptic transmission between nociceptors and their target. In his recent labs, he has been studying the contributions of a third neurotrophin (NT-3) and the effects of altering the synapses involved in transmission between stretch receptors and motor neurons. Mendell's research on neuronal plasticity is specifically focused on the mammalian spinal cord.
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CAPB has been claimed to cause allergic reactions in some users, but a controlled pilot study has found that these cases may represent irritant reactions rather than true allergic reactions. Furthermore, results of human studies have shown that CAPB has a low sensitizing potential if impurities with amidoamine (AA) and dimethylaminopropylamine (DMAPA) are low and tightly controlled. Other studies have concluded that most apparent allergic reactions to CAPB are more likely due to amidoamine. Cocamidopropyl betaine was voted 2004 Allergen of the Year by the American Contact Dermatitis Society.
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Past this period CD3 blocks the TCR- antigen binding and causes conformational change or the removal of the entire TCR3/CD3 complex from the T-cell surface. This lowers the number of available T-cells, perhaps by sensitizing them for the uptake by the epithelial reticular cells. The cross-binding of CD3 molecules as well activates an intracellular signal causing the T cell anergy or apoptosis, unless the cells receive another signal through a co-stimulatory molecule. CD3 antibodies shift the balance from Th1 to Th2 cells as CD3 stimulates Th1 activation.
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Kumar is responsible for managing and implementing a campaign in Delhi with hundreds of volunteers to ensure access to shelters, health-care, skill development, and justice for marginalized people. He has been consistently organizing mass events/rallies, conducting census/surveys, documenting and researching interventions, establishing networks and advocacy groups with government departments, other NGOs, and movements. Kumar has been fighting against social inequality, discrimination and sensitizing civil society for the realization of the larger goal of poor people within India. Kumar is also associated as a research scholar on the issue of homelessness with the Department of Social Work, University of Delhi.
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Toybank has a network of 145 play centers in Mumbai and another 105 outside the city in 9 districts in rural Maharashtra. A library of toys is maintained at each one of these play centers visited by children from poor backgrounds. The toys at the libraries may either be newly bought or collected through the toy collection drives. As of 2016, Toybank is affiliated with 56 partners around the country. Toybank has also been involved in sensitizing teachers about the importance of play in a child’s development through its “Power of Play” workshops in community centers and public schools.
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It may be the case that, in response to antipsychotics, neurons increase the production of D2 receptors (upregulation), thereby sensitizing the neuron to dopamine. However, this is likely an oversimplification, as—despite differences in sensitivity to dopamine of around 3-fold in people that have taken antipsychotics chronically, there is a disproportionately low increase in the amount of D2 receptors in the brain in these people (around 1.4-fold in the striatum of the brain in people with schizophrenia). Other hypotheses include increases in the "active" D2 receptors (termed D2High) relative to the "inactive" conformation (D2Low). The end result is dopamine supersensitivity.
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Normalization of e-cigarette use may lead former cigarette smokers to begin using them, thereby reinstating their nicotine dependence and fostering a return to tobacco use. There is a possible risk of re-normalizing of tobacco use in areas where smoking is banned. Government intervention is recommended to keep children safe from the re-normalizing of tobacco, according to a 2017 review. The "catalyst model" suggests that vaping may proliferate smoking in minors by sensitizing minors to nicotine with the use of a type of nicotine that is more pleasing and without the negative attributes of regular cigarettes.
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In 2011, Schlein was one of the founders of the association of university students known as Progrè, an association that dealt with deepening and sensitizing public opinion on issues related to migration policies and the prison reality. Former Prime Minister Romano Prodi received in support less than 100 centre-left electors and left the presidential election campaign. In April 2013, Schlein gave life to the mobilization campaign known as #OccupyPD, which opposed the formation of a grand coalition government, the Letta Cabinet. In occasion of the 2013 leadership election of the Democratic Party, Schelin gave her support to Giuseppe Civati, who ranked third.
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A new cat was made for each flogging by a bosun's mate and kept in a red baize bag until use. If several dozen lashes were awarded, each could be administered by a fresh bosun's mate—a left-handed one could be included to assure extra painful crisscrossing of the wounds. One dozen was usually awarded as a highly sensitizing prelude to running the gauntlet. For summary punishment of Royal Navy boys, a lighter model was made, the reduced cat, also known as boy's cat, boy's pussy or just pussy, that had only five tails of smooth whip cord.
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Interventions to facilitate child and family coping often begin with providing basic information and education about their illness and treatment procedures, often using videotaped or in vivo models to demonstrate the use of positive coping strategies and teach mastery skills. Other coping interventions include cognitive-behavioral and strength-building interventions, operant reward programs, integrating parent participation, evaluation and mobilization of family and social supports, assisting patient and family in understanding and navigating the medical system, directive and expressive medical play therapy, pain and anxiety management skills training, sensitizing medical staff to patient needs and perceptions, and psychopharmacological interventions.
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Heating the serum destroyed its killing activity. Nevertheless, the heat-inactivated serum, when injected into guinea pigs exposed to the cholera bacteria, maintained its ability to protect the animals from illness. Jules Bordet, a young Belgian scientist in Paris at the Pasteur Institute, concluded that this principle has two components, one that maintained a "sensitizing" effect after being heated and one (alexin) whose toxic effect was lost after being heated. The heat-stable component was responsible for immunity against specific microorganisms, whereas the heat-sensitive component was responsible for the non-specific antimicrobial activity conferred by all normal sera.
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Its principal objectives were to promote, defend and support the women's suffrage movement; to become the focus of action by regional committees; to set up committees in cities where they were absent; and to unite Italian women fighting for voting rights, exploring all legal avenues for obtaining the right for them to vote. In 1906, on behalf of the committee, Mozzoni presented a petition to the Italian Parliament inviting the deputies to discuss granting voting rights to women. While sensitizing parliamentarians to the issue, it was also effective in forming a basis for discussion by women throughout the country.
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The adiponectin genes regulate glucose metabolism as well as fatty acid breakdown; however, the exact mechanisms are not entirely understood. In both human and mice models, adiponectin has been shown to add insulin-sensitizing and anti-inflammatory properties to different types of tissue, specifically muscle and liver tissue. Adiponectin has also been shown to increase the rate of fatty acid transport and oxidation in mice, which causes an increase in fatty acid metabolism. With a high fat diet during gestation, there was an increase in methylation in the promoter of the adiponectin gene accompanied by a decrease in acetylation.
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Thiazolidinediones (TZD), rosiglitazone, and pioglitazone are all used to treat diabetes. These drugs act as agonists of the PPAR-γ receptor leading to insulin sensitizing effects that can improve glycemic control and serum triglyceride levels. Despite the positive effects these chemicals can have in treating diabetes patients, administration also lead to unwanted PPAR-γ mediated side effects such as peripheral edema which can be followed by persistent weight gain if the drug is used over a long period of time. These side effects are particularly prominent in diabetes 2 patients, a disease that tends to result from an overabundance of adipose tissue.
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The concept now is to use the sensitizing light to excite electrons from the deep trap farther from the valence band to the conduction band and then to recombine at the shallow traps nearer to the conduction band. The reference and signal beam would then be used to excite the electrons from the shallow traps back to the deep traps. The information would hence be stored in the deep traps. Reading would be done with the reference beam since the electrons can no longer be excited out of the deep traps by the long wavelength beam.
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A further set of infrared landscapes taken by Wood in Italy in 1911 used plates provided for him by CEK Mees at Wratten & Wainwright. Mees also took a few infrared photographs in Portugal in 1910, which are now in the Kodak archives. Infrared-sensitive photographic plates were developed in the United States during World War I for spectroscopic analysis, and infrared sensitizing dyes were investigated for improved haze penetration in aerial photography.Annual Report of the Director Bureau of Standards to the Secretary of Commerce for the Fiscal Year Ended June 30, 1919 U. S. Govt. Print. Off.
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PUVA (psoralen and ultraviolet A) is an ultraviolet light therapy treatment for skin diseases: Eczema, Psoriasis, Graft-versus-host disease, Vitiligo, Mycosis Fungoides, Large-Plaque Parapsoriasis and Cutaneous T-Cell Lymphoma using the sensitizing effects of the drug psoralen. The psoralen is applied or taken orally to sensitize the skin, then the skin is exposed to UVA. Photodynamic therapy is the general use of nontoxic light-sensitive compounds that are exposed selectively to light, whereupon they become toxic to targeted malignant and other diseased cells. Still, PUVA therapy is often classified as a separate technique from photodynamic therapy.
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GPR 120 is a G protein-coupled receptor (GPCR) and the putative receptor for omega-3 fatty acids including Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA). GPR 120 was among a number of free fatty acid receptors only recently discovered from the human genome database utilizing the GPCR deorphanizing strategy. Binding to the GPR 120 receptor is one of the many putative mechanisms of action for the potential health benefits of consuming omega-3 fatty acids. GPR 120 has specifically shown a role in the in-vivo anti-inflammatory and insulin-sensitizing effects of DHA and EPA in macrophages.
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The integrated hypothesis theory states that trigger points form from excessive release of acetylcholine which produces sustained depolarization of muscle fibers. Indeed, the trigger point has an abnormal biochemical composition with elevated concentrations of acetylcholine, noradrenaline and serotonin and a lower pH. These sustained contractions of muscle sarcomeres compresses local blood supply restricting the energy needs of the local region. This crisis of energy produces sensitizing substances that interact with some nociceptive (pain) nerves traversing in the local region which in turn can produce localized pain within the muscle at the neuromuscular junction (Travell and Simons 1999).
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Contact sensitivity, atopic dermatitis, eczema, and urticaria appear to be related phenomena, the cause of which is generally believed to be the hydrophobic prolamin components of certain Triticeae, Aveneae cultivars. In wheat one of these proteins is ω-gliadin (Gli-B1 gene product). A study of mothers and infants on an allergen-free diet demonstrated that these conditions can be avoided if wheat sensitive cohort in the population avoid wheat in the first year of life. As with exercise induced anaphylaxis, aspirin (also: tartrazine, sodium benzoate, sodium glutamate (MSG), sodium metabisulfite, tyramine) may be sensitizing factors for reactivity.
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The tradenames Brain Education, and Brain Education Systems Training (or BEST), refer to a set of exercises developed and promoted by Ilchi Lee subsequent to his "Brain Respiration" and "Dahnhak." According to Body & Brain's Web site, after more than 27 years of practice, Lee had developed a system of exercises, breathing, and stretches “to activate the natural healing rhythms of the brain and body.” Brain Education is described as consisting of five separate steps: brain sensitizing, brain versatilizing, brain refreshing, brain integrating, and brain mastering. Dr. Ben Goldacre of the U.K. lambasted Ilchi Lee's brain education claims as pseudoscience in his Guardian column "Bad Science" in 2004.
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Claudet was born in La Croix-Rousse son of Claude Claudet, a cloth merchant and Etiennette Julie Montagnat, was active in Great Britain and died in London. He was a student of photography pioneer Louis Daguerre. Claudet headed a glass factory at Choisy-le-Roi together with Georges Bontemps and moved to England to promote the factory with a shop in High Holborn, London. Having acquired a share in L. J. M. Daguerre's invention, he was one of the first to practice daguerreotype portraiture in England, and he improved the sensitizing process by using chlorine (instead of bromine) in addition to iodine, thus gaining greater rapidity of action.
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As she became sterile after 5 successive miscarriages, she invented that she was pregnant to force Jose Carlos to take over the child. In the abandoned place, Nazaré tells Maria do Carmo that his name is Lourdes and promises to take care of the children while Maria do Carmo takes Reginaldo, who had been injured, to the hospital. Being alone with the youngest two months Lindalva in her arms, Nazaré glimpses the chance to realize his plan and kidnap the girl. She sets a fake and pretends to have given birth to the child, sensitizing the lover, who drops his wife and daughter to be with her.
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Some Citrus species contain significant amounts of the phytochemical class called furanocoumarins, a diverse family of naturally occurring organic chemical compounds. In humans, some (not all) of these chemical compounds act as strong photosensitizers when applied topically to the skin, while other furanocoumarins interact with medications when taken orally. The latter is called the “grapefruit juice effect”, a common name for a related group of grapefruit-drug interactions. Due to the photosensitizing effects of certain furanocoumarins, some Citrus species are known to cause phytophotodermatitis, a potentially severe skin inflammation resulting from contact with a light-sensitizing botanical agent followed by exposure to ultraviolet light.
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Vile gossip and scandal spew from the press in the 1888 Puck cartoon Raymond's contribution to journalism, then, was not the introduction of revolutionizing innovations in any department of the profession but a general improving and refining of its tone, a balancing of its parts, sensitizing it to discreet and cultivated popular taste. Taking The Times of London as his model, he tried to combine in his paper the English standard of trustworthiness, stability, inclusiveness, and exclusiveness, with the energy and news initiative of the best American journalism; to preserve in it an integrity of motive and a decorum of conduct such as he possessed as a gentleman.
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A diagram illustrating the distinction between cancer stem cell targeted and conventional cancer therapies Scientists have discovered a molecule on the surface of tumors that appears to promote drug resistance—by converting the tumor cells back into a stem cell-like state. When the tumor cells began to exhibit drug resistance, the cells were simultaneously transforming into a stem cell-like state, which made them impervious to the drugs. It appeared that the treatment itself was driving this transformation by activating a specific molecular pathway. Luckily, several existing drugs, such as Bortezomib for example, can attack this pathway and reverse the cellular transformation, thus ‘re-sensitizing’ the tumor to treatment.
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New and improved sensitizing dyes were developed, and in 1902 the much more evenly color-sensitive Perchromo panchromatic plate was being sold by the German manufacturer Perutz. The commercial availability of highly panchromatic black-and-white emulsions also accelerated the progress of practical color photography, which requires good sensitivity to all the colors of the spectrum for the red, green and blue channels of color information to all be captured with reasonable exposure times. However, all of these were glass-based plate products. Panchromatic emulsions on a film base were not commercially available until the 1910s and did not come into general use until much later.
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The sensitizing risk was brought to public attention by the "poison chair" incident, where Chinese manufacturer Linkwise produced two- seater sofas with DMF sachets inside to inhibit mould while they were in storage or transport. In Finland where the chairs were sold from 2006 to 2007, 60 users sustained serious rashes. The cause was identified as DMF-induced allergic reaction by Tapio Rantanen from Finland and his original article became the cover story in the July 2008 issue of the British Journal of Dermatology. In the United Kingdom, sofas sold by Argos, Land of Leather and Walmsley Furnishing containing the chemical caused over a hundred injuries.
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According to Steve Rothman, the NIF San Francisco director, "Things have definitely improved, particularly in sensitizing people to the existence of racism in Israeli society."A noble goal: Can Israel give soccer racism the boot?, by Joe Eskenazi, JWeekly In 2006, Israel joined Football Against Racism in Europe (FARE), network set up to counter racism in soccer.Israel joins fight against soccer racism, by MATT ZALEN, Jerusalem Post After a soccer game in March 2012, in which Beitar Jerusalem defeated a rival team at Jerusalem's Teddy Stadium, a group of at least a hundred Beitar fans entered the nearby Malha Mall chanting racist slogans and allegedly attacked Arab cleaning workers, whom some reports described as Palestinians.
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Bagchi, p. 124 Since its inception, it has been working as an advocacy group for sex workers and over the years, it has worked towards sensitizing general public about rights of sex workers, often initiating debate and discussion in public media and press, besides advocating abolition of 'The Immoral Traffic (Prevention) Act, 1956' (PITA), and legalisation of sex work. Many sex workers now have voters identity cards, health insurance and even bank accounts. In 1995, its consumer cooperative society and micro-credit programme, 'Usha' (literally meaning light), ensured that the Government of West Bengal altered the state's cooperative law to register it as a sex workers cooperative, instead of a 'housewives cooperative' under the prevalent state laws.
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In various rodent models, 20-HETE, at low concentrations (<50 nanomolar), acts to constrict arteries by sensitizing (i.e. increasing) the contraction responses of these artery's smooth muscle cells to other contracting agents such as alpha adrenergic agonists, vasopressin, endothelin, and a product of renin angiotensin system, angiotensin II. 20-HETE has a particularly complex interaction with the renin angiotensin system: angiotensin II stimulates the preglomerular microvessels of the rat kidney to produce 20-HETE; this production is required for angiotensin II to exert its full constrictor effects; and 20-HETE induces transcription of the enzyme which converts angiotensin I to angiotensin II, i.e. angiotensin-converting enzyme. Other agents such as Androgens and alpha adrenergic compounds such as norepinephrine.
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The use of the crop in show-jumping competition does not result in better performance, according to a study conducted in 2013 in the UK. In this sport, other abuses intended to force the horse to "respect" the bars are regularly found: coating the legs with the sensitizing product, training with metal bars that cause great pain when hit, or tightening the rear gaiters in such a way as to act on a tendon. Endurance competitions are often at the heart of scandals involving the death of mounts during or after the competition, as well as a large number of doping cases. These problems likely result from a cultural conflict between Western and Middle Eastern riders.
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In photography, the Collodion process was invented in 1851 by Frederick Scott Archer. This invention required only two to three seconds of light exposure to produce an image, but plates had to be sensitized at the time of exposure, exposed while the emulsion was still wet, and processed immediately after exposure in the camera. When he noticed that his health was being affected by the 'wet' collodion's ether vapor, Maddox began looking for a substitute. He suggested in the 8 September 1871 British Journal of Photography article An Experiment with Gelatino-Bromide that sensitizing chemicals cadmium bromide and silver nitrate should be coated on a glass plate in gelatin, a transparent substance used for making candies.
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The Rh system (Rh meaning Rhesus) is the second most significant blood-group system in human-blood transfusion with currently 50 antigens. The most significant Rh antigen is the D antigen, because it is the most likely to provoke an immune system response of the five main Rh antigens. It is common for D-negative individuals not to have any anti-D IgG or IgM antibodies, because anti-D antibodies are not usually produced by sensitization against environmental substances. However, D-negative individuals can produce IgG anti-D antibodies following a sensitizing event: possibly a fetomaternal transfusion of blood from a fetus in pregnancy or occasionally a blood transfusion with D positive RBCs.
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In Crisálida she assumed the role of project coordinator for 2013–2014, taking charge of the library's Trans Labor Inclusion Line, where she coordinated education and job training for members of the community. She focused her visibility work on sensitizing society as a trainer, setting up the 2012 to 2016 "Right to Identity" workshop for the Tucumán Security Forces, and teaching the workshop until her death in 2014. She also led the aforementioned workshop at the National University of Tucumán's Faculty of Philosophy and Letters and for the Ombudsman of Tucumán. She also participated in the university volunteering project "Youth, Sexual and Reproductive Rights, and Diversity" (DSyR) and the publication of its results.
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In 1992, Worden retired from Kodak and set up a consulting firm located in Santee, South Carolina. After Worden retired, he began to buy confidential data from another former Kodak employee, Kurt Strobl, at Kodak and from 63 other former Kodak colleagues. He also hired many former Kodak employees to work at his firm. From these actions, Worden was able to obtain a book containing every secret Kodak manufacturing formula with details of every chemical makeup of film base and coating, a book containing specifications for a $500 million film sensitizing facility, a collection of secret trouble- shooting procedures for the manufacturing of acetate, and a collection of techniques for inspecting and testing finished film base.
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The instability of early sensitizing dyes and their tendency to rapidly cause fogging initially confined their use to the laboratory, but in 1883 the first commercially dye-sensitized plates appeared on the market. These early products, described as isochromatic or orthochromatic depending on the manufacturer, made possible a more accurate rendering of colored subject matter into a black-and-white image. Because they were still disproportionately sensitive to blue, the use of a yellow filter and a consequently longer exposure time were required to take full advantage of their extended sensitivity. In 1894, the Lumière Brothers introduced their Lumière Panchromatic plate, which was made sensitive, although very unequally, to all colors including red.
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The Bank of France is in charge of offering services households in severe financial difficulty. This includes the management of over-indebtedness (one of the major tasks of the local branches of the bank), and the guarantee to an access to basic banking services for everyone, such as the right to a basic bank account. It is also in charge of financial and economic education of the general public, by developing an economic culture among specific populations (like youngsters and households in severe financial difficulty). This includes sensitizing high school students, providing online information and educational services, training social workers and the launch of the French Cité de l'économie et de la monnaie (Citéco), a museum based in the 17th district of Paris, in 2019.
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Recently, the Department of Telecommunications, Government of India has instructed all the telecom service providers in the country and TERM Cells to initiate following actions on frauds related to installation of towers and seeking advance: #Spreading awareness among general public by publishing public notices in leading newspapers in respective areas of operation on a periodical basis. #Sensitizing the general public of the issue by uploading public notices on respective websites. #Educating subscribers of the matter by sending them SMS. #Where such incidences are reported, TERM Cells are asked to bring matter into knowledge of the Superintendent/Commissioners and Director General of Police to take action on such cases wherein it is observed that name/logo of DoT has been used illegally.
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While the density of pure crystalline ammonium nitrate is 1700 kg/m3, individual prills of explosive-grade AN measure approximately 1300 kg/m3. Their lower density is due to the presence of a small spherical air pocket within each prill: this is the primary difference between AN sold for blasting and that sold for agricultural use. These voids are necessary to sensitize ANFO: they create so-called "hot spots".It was found by the IRA, in response to using low-brisance AN fertilizers, that "hot spots" can be created by blending powdered sugar into the ANFO mixture, effectively sensitizing the mixture to mining-standard prilled ammonium nitrate effectiveness in which the interaction of the detonation front with a spherical void concentrates energy.
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It utilized the photosensitivity of dichromated gelatin, discovered in 1852 by Henry Fox Talbot, who was thereby building on Mungo Ponton's 1839 contribution of potassium dichromate to the list of known sensitizing agents for making photographs on paper. The photochemical formation of the gelatin relief dates back to the first carbon printing patent of Alphonse Poitevin (1855). The idea of washing unhardened gelatin from the lower part of an exposed gelatin layer can be found in the early experiments of Adolphe Fargier (1861) and in the development of Joseph Swan’s fully practical carbon-transfer process (1864). Alois Auer, in his 1853 book on nature printing, describes making printing plates by forcibly impressing soft low-relief objects, such as leaves, into sheets of lead.
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When enteropathy develops in early childhood, symptomatic disease is more rapidly evident. A survey of geriatrics with celiac disease in Finland revealed that the incidence of disease was much higher than the general population. Allergic disease may rise or fall with age; certain evidence points to the increased or daily use of non-steroidal anti-inflammatory factors (aspirin, ibuprofen) as an increased risk factor for urticaria or anaphylaxis, and the sensitizing dose may include low-dose aspirin therapy used in the treatment of heart disease. NCGS may be a late- onset condition: in a prospective study performed among adults of 18 to 80 years, the median age of disease onset was found to be 55 years, with a six times higher prevalence in females than in males.
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In a few processes, the three images were created one on top of another by repeated coating or re-sensitizing, negative registration, exposure and development operations. A number of variations were devised and marketed during the first half of the 20th century, some of them short-lived, others, such as the Trichrome Carbro process, enduring for several decades. Because some of these processes allow very stable and light-fast coloring matter to be used, yielding images which can remain virtually unchanged for centuries, they are still not quite completely extinct. The production of photographic three-color prints on paper was pioneered by Louis Ducos du Hauron, whose comprehensive 1868 French patent also included the basic concepts of most of the color photographic processes which were subsequently developed.
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Each of the three layers in the proposed film would be sensitive to one of the three primary colors, and each of the three layers would have substances (called "color couplers") embedded in them that would form a dye of the required color when combined with the by- products of the developing silver image. When the silver images were bleached away, the three-color dye image would remain. Fischer himself did not find a way to stop the color couplers and color sensitizing dyes from wandering from one layer into the other, where they would produce unwanted colors. Mannes and Godowsky followed that route, started experimenting with color couplers, but their experiments were hindered by a lack of money, supplies and facilities.
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The organization achieves its overall program goals acting in public life, and it deals with: advocacy and lobbying human rights of LGBTIQ persons at national, European and international level; supporting and participating in the organization of public meetings of LGBTIQ person, Pride events and parades in our country, the region and abroad in order to increase the visibility of LGBT persons and advocacy for protection of human rights; sensitizing the public to promote the interests and improve the position of LGBTIQ people ; encouraging self-organization of young LGBT people for exercising their rights; providing free legal aid and psychosocial support and counseling for LGBT people ; organization of workshops, courses, lectures, seminars, forums, conferences and other activities ; organizing the festivals of queer arts and culture and other events.
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Within a few years, exposures had been reduced to as little as a few seconds by the use of additional sensitizing chemicals and "faster" lenses such as Petzval's portrait lens, the first mathematically calculated lens. The daguerreotype was the Polaroid film of its day: it produced a unique image which could only be duplicated by using a camera to photograph the original. Despite this drawback, millions of daguerreotypes were produced. The paper-based calotype process, introduced by Henry Fox Talbot in 1841, allowed the production of an unlimited number of copies by simple contact printing, but it had its own shortcomings—the grain of the paper was obtrusively visible in the image, and the extremely fine detail of which the daguerreotype was capable was not possible.
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A second advantage of this approach is, that the second flame detector is a redundant one, in case the first one is not working or is blinded. In general, when mounting several flame detectors, one should let them "look" to each other not let them look to the walls. Following this procedure blind spots (caused by the shadow effect) can be avoided and a better redundancy can be achieved than if the flame detectors would "look" from the central position into the area to be protected. The range of flame detectors to the 30 x 30 cm, 1 x 1-foot industry standard fire is stated within the manufacturers data sheets and manuals, this range can be affected by the previously stated de-sensitizing effects of sunlight, water, fog, steam and blackbody radiation.
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" In contrast to the neo-Platonic and Christian approach, moreover, Talmudic thought does not "make any legal distinction between formed and unformed foetuses,"Jakobovits, Jewish Medical Ethics, p.182f. after the 40th day. Feldman, likewise, is emphatically comparative, saying: "... while Christianity's position on abortion has raised the moral level of western civilization in this regard and has succeeded in sensitizing humanity to a greater reverence for life, it is obviously comprised, at the same time, of theological postulates which the Jewish community can not share." Feldman also points out that Talmudic debate over whether the soul achieves immortality upon conception, or at a far later stage, has little bearing on halakhic protections for the fetus because, absent a doctrine of original sin, "abortion would not interfere with the immortal rights or destiny of the foetus.
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Governments recognize the "Slave Route" as an educational and tourist-worthy part of the cultural heritage, but not the people themselves. Salgado pressed for the government to take a census of the Afro-Chilean population, as well as to sponsor programs to destigmatize participation in events designed to promote their culture, sensitizing the public to their right to have their ethnic identity protected. Between 2004 and 2008, Salgado was a member of the consulting committee of the Chilean Advisory Panel on Culture and the Arts (), as a representative of the Afro-Chilean community. After more than a decade of pressuring the government, to prepare a statistical analysis of the Afro-Chilean community, Salgado and other activists were successful in obtaining a regional survey in 2011, but not in gaining national inclusion in the federal census as an ethnic minority.
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Diffusion tensor imaging (DTI) is a magnetic resonance imaging technique that enables the measurement of the restricted diffusion of water in tissue in order to produce neural tract images instead of using this data solely for the purpose of assigning contrast or colors to pixels in a cross-sectional image. It also provides useful structural information about muscle—including heart muscle—as well as other tissues such as the prostate. In DTI, each voxel has one or more pairs of parameters: a rate of diffusion and a preferred direction of diffusion-- described in terms of three-dimensional space--for which that parameter is valid. The properties of each voxel of a single DTI image is usually calculated by vector or tensor math from six or more different diffusion weighted acquisitions, each obtained with a different orientation of the diffusion sensitizing gradients.
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Methylisothiazolinone, MIT, or MI, (sometimes erroneously called methylisothiazoline), is a powerful synthetic biocide and preservative within the group of isothiazolinones, which is used in numerous personal care products and a wide range of industrial applications. It is a cytotoxin that may affect different types of cells. Its use for a wide range of personal products for humans, such as cosmetics, lotions, moisturizers, sanitary wipes, shampoos, and sunscreens, more than doubled during the first decade of the twenty-first century and has been reported as a contact sensitizing agent by the European Commission’s Scientific Committee on Consumer Safety. Industrial applications also are quite wide ranging, from preservative and sanitizing uses to antimicrobial agents, energy production, metalworking fluids, mining, paint manufacturing, and paper manufacturing, many of which increase potential exposure to it by humans as well as organisms, both terrestrial and marine.
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India Inclusion Summit an initiative supported by SAP SE, J.P. Morgan, Australia and New Zealand Banking Group Limited, Allegis Group brings together thought leaders working in the field of inclusion to deliberate, discuss and take forward different talents available in the society. The Summit aims to be an egalitarian platform attracting people from a range of fields. It mainly focused on 'Inclusion'- the idea that all people should freely, openly and without pity or sympathy accommodate any person with any kind of disability, physical, mental or intellectual, without restrictions or limitations of any kind. The summit aims at sensitizing the public on issues related to people with IDD (intellectual development disability) & physical disability through cinema, sports, books and media and will leverage the support of these well- known personalities to further the cause of an inclusive society, a press release said.
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A carbon print is a photographic print with an image consisting of pigmented gelatin, rather than of silver or other metallic particles suspended in a uniform layer of gelatin, as in typical black-and-white prints, or of chromogenic dyes, as in typical photographic color prints. 1932 Carbro process color print by Nickolas Muray In the original version of the printing process, carbon tissue (a temporary support sheet coated with a layer of gelatin mixed with a pigment—originally carbon black, from which the name derives) is bathed in a potassium dichromate sensitizing solution, dried, then exposed to strong ultraviolet light through a photographic negative, hardening the gelatin in proportion to the amount of light reaching it. The tissue is then developed by treatment with warm water, which dissolves the unhardened gelatin. The resulting pigment image is physically transferred to a final support surface, either directly or indirectly.
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Accordingly, parties could tackle major challenges in the implementation of the 2005 Convention by: # Streamlining and harmonizing data and information required for national and global monitoring purposes; # Encouraging research networks and statistical offices around the world to use the Global Report monitoring framework, its core indicators and means of verification as a basis for their data collection and the establishing of statistical baselines; # Filling existing data gaps identified in the two Global reports referring to key cultural policy areas, such as trade in cultural services, mobility flows, culture in the digital environment, or gender-disaggregated data; # Raising awareness among policy decision makers for cultural policy reforms; # Building capacities on policy monitoring; # Sensitizing the development community with regard to the creative sector's potential not only contributes to the creation of jobs and income, but also catalyzes innovation, permeating traditional development areas such as education and gender equality, and brings about change.
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From a more STS perspective, Sheila Jasanoff, has written that "Co-production is shorthand for the proposition that the ways in which we know and represent the world (both nature and society) are inseparable from the ways in which we chose to live in." Co-production draws on constitutive (such as Actor–network theory) and interactional work (such as the Edinburgh School) in STS. As a sensitizing concept, the idiom of co-production looks at four themes: "the emergence and stabilization of new techno-scientific objects and framings, the resolution of scientific and technical controversies; the processes by which the products of techno-science are made intelligible and portable across boundaries; and the adjustment of science’s cultural practices in response to the contexts in which science is done." Studies employing co-production often follow the following pathways: "making identities, making institutions, making discourses, and making representations"Jasanoff, Sheila.
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The center has discovered the mechanism of action underlying the anti-inflammatory actions of Conjugated linoleic acid in inflammatory bowel disease, and the insulin sensitizing and anti-inflammatory effects of abscisic acid. Its Center for Modeling Immunity to Enteric Pathogens Program is applying high performance computing techniques to model and simulate human immunology systems and help immunologists conduct quick in silico experiments to narrow down experimental design, validate their hypotheses and save significant time and laboratory cost. This laboratory is also collaborating with the Center for Global Health at the University of Virginia, the Department of Gastroenterology and the University of North Carolina at Chapel Hill and other medical schools and leading several human clinical trials on safer therapies for inflammatory and immune mediated diseases. It has recently established a partnership with the Division of Gastroenterology at the Carilion Clinic to launch a joint translational research program in inflammatory bowel diseases.
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While working as a research fellow at Harvard in the early 1980s, Poretsky became known for discovering, describing and characterizing insulin receptors in the human ovary. Before his research, the hormone insulin had been known to primarily regulate glucose and other fuel metabolism in the liver, fat, and muscle. His work established the ovary as a target for regulation by insulin, and introduced a new paradigm for the gonadotropic function of insulin. Poretsky had been researching the causes of hyperandrogenism (high level of male hormones and male features in females) in patients with extreme forms of insulin resistance, for example in people with insulin receptor gene mutations. Subsequently, Poretsky’s work became important for understanding more common disorders, such as polycystic ovary syndrome (PCOS), which affects up to 10% of reproductive age women and is associated with infertility and diabetes. Poretsky’s work helped lead to the use of insulin-sensitizing agents in patients with PCOS.
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Methaneseleninic acid shows potential anticancer activity and is a model for studying the anticancer effects of selenium in vitro. Methaneseleninic acid shows superior in vivo inhibitory efficacy toward human prostate cancer compared to selenomethionine or selenite (ion). It has recently been reported that methaneseleninic acid enhances the efficacy of paclitaxel for treatment of triple-negative breast cancer, that methaneseleninic acid functions as an aromatase inhibitor, of possible use in therapy for estrogen receptor-positive breast cancer in postmenopausal women, that methaneseleninic acid shows promise as a sensitizing agent for apoptosis induced by the Bcl-2-family inhibitor ABT-737 in several cancer lines, and that methaneseleninic acid restricts tumor growth in the nude mouse model of metastatic breast cancer and Lewis lung carcinoma in mice. Methaneselenol (CH3SeH) can be produced in vivo by reduction of methaneseleninic acid and may in fact be the key metabolite responsible for selenium’s anticancer activity through generation of superoxide.
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It featured 2Baba, Ahmed Soultan, Ben Pol, Teni the Entertainer, Yemi Alade, Amanda Black, Stanley Enow, Gigi La Mayne, Prodigio and Betty G; artists from all over the continent of Africa. The project had to be produced and recorded remotely due to corona virus travel restrictions. In January 2019, he produced Not for Sale, the official anthem for Vote Not Fight, an electoral awareness campaign organised by the European Centre for Electoral Support (ECES) in partnership with Nigeria’s electoral organisation, the Independent National Electoral Commission (INEC). The campaign which was aimed at sensitizing Nigerians to their voting rights and encouraging them not to sell their votes, employed the additional talents of notable Nigerian musicians 2Baba, MI, Teni, Niniola, Waje, and others. In the same year Cobhams created the song For Every Child as the theme song for the celebration of the adoption of UNICEF’s CRC (Convention of the Rights of the Child) in Nigeria.
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Historians would generally assume that the failure to reform (too many vested interests, lack of coordination in the reforming coalition) would eventually lead to a greater upheaval or even revolution, since the system must eventually be adjusted or disintegrate, and the failure of the Conciliar movement helped lead to the Protestant Reformation in Europe. These frustrated reformist movements ranged from nominalism, devotio moderna (modern devotion), to humanism occurring in conjunction with economic, political and demographic forces that contributed to a growing disaffection with the wealth and power of the elite clergy, sensitizing the population to the financial and moral corruption of the secular Renaissance church. The outcome of the Black Death encouraged a radical reorganization of the economy, and eventually of European society. In the emerging urban centers, however, the calamities of the fourteenth and early fifteenth century, and the resultant labor shortages, provided a strong impetus for economic diversification and technological innovations.
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Prior to the late 1890s color photography was strictly the domain of a very few intrepid experimenters willing to build their own equipment, do their own color- sensitizing of photographic emulsions, make and test their own color filters and otherwise devote a large amount of time and effort to their pursuits. There were many opportunities for something to go wrong during the series of operations required and problem-free results were rare. Most photographers still regarded the whole idea of color photography as a pipe dream, something only madmen and swindlers would claim to have accomplished. In 1898, however, it was possible to buy the required equipment and supplies ready-made. Two adequately red-sensitive photographic platesAbney, W: "Orthochromatic photography", Journal of the Society of Arts, May 22, 1896 44:587–597 describes and illustrates (with spectrum photographs and curves) the characteristics of the Lumière Panchromatic and Cadett Spectrum plates as of 1896.
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The FFRP was responsible for drafting and introducing the Gender-Based Violence Bill (GBV), a private members bill and the only bill so far, at that point in time, to have originated outside of the executive branch of government. The process of drafting the original bill began in early 2005, when the FFRP mobilized its members and reached out to community leaders across the country to gather information and recommendations from the general population on how to define, prevent and appropriately punish acts of GBV. Following initial community outreach, a mass-media campaign began with the intention of raising awareness and sensitizing the country to the problem of GBV. Later on in the year, female parliamentarians of the FFRP returned to the field again to consult further with communities regarding the bill, and worked in collaboration with NAWOCO to conduct discussion sessions with women only, in addition to the discussions already taking place that involved both women and men.
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This was the case leading up to the Protestant Reformation. Following the breakdown of monastic institutions and scholasticism in late medieval Europe, accentuated by the "Babylonian Captivity" of the Avignon Papacy, the Great Schism, and the failure of the Conciliar movement, the 16th century saw the fomenting of a great cultural debate about religious reforms and later fundamental religious values. Historians would generally assume that the failure to reform (too many vested interests, lack of coordination in the reforming coalition) would eventually lead to a greater upheaval or even revolution since the system must eventually be adjusted or disintegrate, and the failure of the Conciliar movement helped lead to the Protestant Reformation in Europe. These frustrated reformist movements ranged from nominalism, devotio moderna (modern devotion), to humanism occurring in conjunction with economic, political and demographic forces that contributed to a growing disaffection with the wealth and power of the elite clergy, sensitizing the population to the financial and moral corruption of the secular Renaissance church.
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There are 23 objectives and commitments listed in the draft agreement. These include collecting and using accurate and anonymized data to develop evidence-based migration policy, ensuring that all migrants have proof of identity, enhancing availability and flexibility for regular migration, encouraging cooperation for tracking missing migrants and saving lives, ensuring migrants can access basic services, and making provisions for both full inclusion of migrants and social cohesion. The draft agreement recognises the principles of national sovereignty: The agreement lists actions for governments to draw from, including to "promote independent, objective and quality reporting of media outlets, including internet-based information, including by sensitizing and educating media professionals on migration-related issues and terminology" and to "support multicultural activities through sports, music, arts, culinary festivals, volunteering and other social events". The agreement makes no distinction between illegal and legal migrants, but does distinguish repeatedly between regular and irregular migrants, affirms the right of states to distinguish between regular and irregular migration status,Section 15, p.
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He spoke of the "assassination of MLK and its implication on white America.... (to those that mourned his assassination) Tears are not enough... (to those that inherited white racism) there will be no rest", blamed both sets of whites for the death, and then addressed the black students to question if "'law and order' was orderly racism, not justice." In May an essay by Thomas' was first place in a campus contest in the humanities school with reviewers affirming it as both highly scholarly and an organic expression of culture. Thomas' award winning essay begins as an analysis/reflection of Camus' The Stranger and The Plague as going towards a new morality, a new humanism: "a shift, a deliberate sensitizing of the basic components of humanity that are a very real and essential part of us – to extend ourselves into another person's soul as they are." And that year Nine Black Poets was published which included Thomas' work, considered one of the significant works of the year, though at least one reviewer found the attention of calling to God tiresome.
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HIJRA's protection programming targeting refugees in western Uganda, envisages a community that is able to be self-reliant in the provision of protection for the vulnerable including unaccompanied, separated children and those at risk of abuse, exploitation and neglect as well as a continued reduction of the SGBV incidences. HIJRA has been able to improve the access of Persons-of- Concern to legal assistance through the provision of probono legal services such as legal representation, facilitating of witnesses and interpreters to court in addition to other legal services. The programme has also played a role in reducing crime by conducting community policing sessions within and around the Settlement and sensitizing the communities on the laws of Uganda. The programme has facilitated the establishment of a well-organized community with security structures that are able to prevent, detect and report crime to relevant authorities; by mean of strengthening of community-based structures along with the capacity building of the several authorities such as police and the Refugee Welfare Committee members in charge of defense.
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BasicNeeds was set up because of the factors which the WHO report highlighted, and through its programs attempts to ensure that mental health is given due attention. BasicNeeds' mission is to enable people living with mental illness and epilepsy and their families to live and work successfully in their communities by combining health, socio- economic and community oriented solutions with changes in policy, practice and resource allocation. BasicNeeds' innovative Model for Mental Health and Development takes a holistic approach to community-based mental health care and consists of five inter-linking modules: # Capacity building: Identifying, mobilizing, sensitizing and training mental health and development stakeholders # Community Mental Health: Enabling effective and affordable community oriented mental health treatment services # Livelihoods: Facilitating opportunities for affected individuals to gain or regain the ability to work, earn and contribute to family and community life # Research: Generating evidence from the practice of mental health and development # Collaboration: Forging partnerships with stakeholders who are involved in implementing the model on the ground and/or are responsible for policy and practice decisions to improve mental health provision.
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Such a lens was necessary in order to produce the highly detailed results which had elicited so much astonishment and praise when daguerreotypes were first exhibited, results which the purchasers of daguerreotype equipment expected to achieve,Using this lens and the original sensitizing method, an exposure of several minutes was required to photograph even a very brightly sunlit scene. A much "faster" lens could have been provided—simply omitting the integral fixed diaphragm from the Chevalier lens would have increased its working aperture to about f/4.7 and reduced the exposure time by nearly 90 percent—but because of the existing state of lens design the much shorter exposure would have been at the cost of a peripherally distorted and very much less clear image. With uncommon exceptions, daguerreotypes made before 1841 were of static subjects such as landscapes, buildings, monuments, statuary, and still life arrangements. Attempts at portrait photography with the Chevalier lens required the sitter to face into the sun for several minutes while trying to remain motionless and look pleasant, usually producing repulsive and unflattering results.
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In 1985, as part of the International Youth Year, Sylvie Cotton and Claire Bourque founded the art gallery DARE-DARE. They then gave a first three-part mandate to the center: to allow young artists to exhibit and sell their works, to offer a transitional venue to artists before entering the established galleries, and finally, to educate the general population (and especially the local people) on current art practices. Located at this time on Laurier Street, the center presented a new exhibition every two weeks, totalling 28 artists of different disciplines in the first year. With the initial aim of sensitizing new audiences, the center has supported and still supports the efforts of artists who wish to meet other audiences and compare their practice with a specific context different from that of the workshop or the gallery. 8 The center is at the origin of many events: the Festival des musiciennes innovatrices (1986), Art et littérature féministe (1988), Dansité (1988), 11 artistes dans leurs quartiers (1990), Les Femmes l’Art et la Joie (as part of the Center's fifth anniversary in 1990) and Les Cracheurs d'images (1993).
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As a Harvard undergraduate, Robert F. Kennedy attended a meeting of students at which he stood up and challenged Feeney, later storming out following the priest's assertion that there was no salvation outside the Catholic faith. A similarly negative reaction to Feeney's teaching was recorded by British novelist and Catholic convert Evelyn Waugh, who wrote of visiting the priest while in the United States:The Letters of Evelyn Waugh (1980), 292–3. A few years later Feeney wrote critically of Knox and Newman in his collection of essays London is a Place, with an unsympathetic passing reference to Waugh's biography of St. Helena: In 2003, in an article for The Jewish Week newspaper, editor Gary Rosenblatt wrote: > In a lesser-known case, Richard Cardinal Cushing excommunicated a priest, > Leonard Feeney, in 1953, for preaching that all non-Catholics would go to > Hell.Even though Father Feeney’s words were based on the Gospel, Cardinal > Cushing found them offensive, in large part because his sister had married a > Jew, said Carroll, and the Cardinal had grown close to the family, > sensitizing him to the Jewish perspective toward proselytization.
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