121 Sentences With "results in the loss of"

He said this directly results in the loss of jobs and substantial decline in revenue.

Phillips lives with spinal muscular atrophy (SMA), a genetic disease that results in the loss of voluntary muscle movement.

After a visit to the doctor, Thomas learned he had vitiligo, a skin disorder that results in the loss of pigmentation.

"We really don't know the causal pathway that causes the loss of connection in the brain that results in the loss of cognitive abilities [in Alzheimer's patients]," said Breitner.

By studying mice, researchers at Stanford have found that a lack of dietary fiber — which is missing from most processed foods — results in the loss of important bacterial strains.

"While many of the objectives of the recent raid in Yemen were met, I would not describe any operation that results in the loss of American life as a success," McCain said in a statement.

"While many of the objectives of the recent raid in Yemen were met, I would not describe any operation that results in the loss of American life as a success," McCain said in the statement.

Now 9 years old, the fourth grader of North Tonawanda, New York, has Lysosomal acid lipase deficiency, a rare, life-threatening condition that results in the loss of enzyme activity, multi-organ damage and, often, premature death.

The degenerative neurological disorder, which was the cause behind the Ice Bucket Challenge that swept the internet in 2014, results in the loss of motor function, with eyes commonly being the last remaining muscle that can move.

Mice with mutations in the gene for MITF have an overactive response to viruses that results in the loss of melanocytes and melanocyte stem cells in the hair bulb, and this results in hair graying, the study team reports.

The pro-Erdogan collective has taken over a variety of prominent accounts, changing their photos and username — which results in the loss of the verified checkmark — while posting pro-Turkey messages and claiming to obtain contents of the victims' direct messages.

The dead zone in the Chesapeake Bay, for instance -- which measures 403 cubic miles, or nearly the volume of 3.2 million Olympic-size swimming pools -- results in the loss of tens of millions of fish, which both humans and crabs eat.

In a statement on its website responding to the snitch scandal, the league defends its actions writing that it has "a responsibility to protect the clubs and their fans" from unlicensed broadcasts being made in public places, claiming that such activity results in the loss of an estimated €150M annually from the league.

"The radiograph showed at least 14 to 15 puppies, so we decided on a C-section because a natural birth for a litter that size would be a long delivery for the mother and often results in the loss of puppies because of the long delivery process," Dr. Aime Johnson professor and theriogenologist at the school said of Bailey's predicament.

On the other hand, too high a level results in the loss of dynamic range.

The insertion and subsequent expression of hobo-like sequences results in the loss of germ cells in the gonads of developing flies.

This often results in the loss of the child as well as the rejection of the woman by her husband and others.

A second type of NSD has been observed in yeast. In this mechanism, the absence of Ski7 results in the loss of poly-A tail binding PABP proteins by the action of the translation ribosome. The removal of these PABP proteins then results in the loss of the protective 5'm7G cap. The loss of the cap results in rapid degradation of the transcript by an endogenous 5'-3' exonuclease such as XrnI.

Malden, MA : Blackwell Publishing. He also did pioneering research in schizophrenia, especially focusing on how deterioration and deficit results in the loss of normal functioning.Milite , George. (2001). Shakow, David (1901-1981).

If a player makes contact with the set, it results in the loss of the point. Even if the player hit a "kill shot", they will lose the point if they touch the set before the ball makes contact with the ground.

Schaefer, 243.Reefer Madness reprint. Anne's drug use results in the loss of many of her inhibitions, and the film shows her actions under the influence, including scenes implying sexual promiscuity. As the film progresses, she is fired from her job and begins selling drugs for Markey.

Failure to follow suit, criticising or verbally trying to influence the game generally results in the loss of the game. If a trick is not yet completed (i.e. the cards are still face up on the table), each player has the right to view the previous trick on request.

Beekeepers often combine nucs together in the fall to produce a single, strong colony. This results in the loss of all but one queen, but provides a colony capable of surviving winter. In warm climates, nucs can overwinter. Nucs can also survive winter indoors, or in an observation hive.

Attenuation: In addition to geometric spreading, absorption and scattering of energy during propagation results in the loss of energy. The attenuation length is the distance at which intensity drops to 1/e(37%) to initial intensity. Environmental factors such as fog, rain and turbulence disturb signal transmission and decreases attenuation length.

Loss of KCC2 following neuronal damage (i.e. ischemia, spinal cord damage, physical trauma to the central nervous system) results in the loss of inhibitory regulation and the subsequent development of neuronal hyperexcitability, motor spasticity, and seizure-like activity as GABAA receptors and glycine receptors revert from hyperpolarizing to depolarizing postsynaptic effects.

When Sqoon has reached its maximum capacity of nine humans, the player must discharge survivors onto an island which will then release power-ups and replenish fuel. Sqoon has a fuel supply which must be replenished every sixty seconds. Failure to do so results in the loss of a life.

An unnamed narrator refuses to pay his landlord when she raises the rent on him. In the end, his insistence upon maintaining his sense of "self-respect" results in the loss of his house. Consequently, he sends his family off to "visit" his parents, while he searches for a new job.

Dehydration of the at the pentanone substituted alcohol group is also possible, following an E1 reaction mechanism. This reaction is acid-catalyzed and results in the loss of a water molecule. Like with the SN1 reaction, protonation of the leaving group is required first. Water then is eliminated, leaving behind a carbocation, which leads eventually to alkene formation.

Loss of all shields results in the loss of one of three credits, or continues, and loss of all continues results in the player seeing the game over screen. The game uses a unique leveling system, in which the player gains experience from defeated enemies to gain newer, more powerful versions of the weapons the player has access to.

Such greedy protocols tend to increase latency and packet loss for all users. The amount of over-provisioning in interior links required to replace QoS depends on the number of users and their traffic demands. This limits usability of over-provisioning. Newer more bandwidth intensive applications and the addition of more users results in the loss of over-provisioned networks.

Flame lift-off in oil fired pressure jet burners is an unwanted condition in which the flame and burner become separated. This condition is most commonly created by excessive combustion air and often results in the loss of flame as the photoelectric cell fails to register the light of the flame, this in turn results in a safety lockout of the control box.

In the final episode of the original series, Nadine suffers a blow to the head that results in the loss of her delusions of teenhood. Apparently, she has no memory of anything that has occurred since her suicide attempt. 25 years later, Nadine is an avid viewer of Lawrence Jacoby's "Dr. Amp" web series and has turned her silent drape-runners into a business.

The dam site is located upstream of the ruins of the Great Dam. The new dam, like the old, was designed to store water for irrigating the Ma'rib plains. However, the wadi bed at the new dam site consists of alluvial sand and gravel material 30–50 m thick. Seepage that emanates from this dam does not threaten its structure, but results in the loss of water.

Epic is an action-based space flight simulator game. It features eight completely different levels (including two in two phases), which take place either in space or over the surface of a planet. Each has a tight time limit to complete the mission (destroying the assigned targets); failure results in the loss of one of the player's ships and may affect the gameplay in subsequent missions.

Studies have shown that a mutated COL2A1 gene is responsible for all type II chondroldysplasias, including Kniest dysplasia. It is believed that point mutations or the alteration of splice sites in COL2A1 domains will result in Kniest Dysplasia. The COL2A1 domain typically spans between exon 12 and 24. Mutations that occur at a splice donor site results in the loss of function at that site.

Before a unit fires at enemy infantry, the firing player must decide on either Normal or Suppressive fire. If Normal fire is chosen, then each hit results in the loss of one infantry figure from the targeted squad; a casualty. The figure is removed from the squad base and put back in the box. The defender chooses which specific figures are lost and in what order.

An electrocuted megabat on overhead power lines in Australia Megabats are threatened by habitat destruction by humans. Deforestation of their habitats has resulted in the loss of critical roosting habitat. Deforestation also results in the loss of food resource, as native fruit-bearing trees are felled. Habitat loss and resulting urbanization leads to construction of new roadways, making megabat colonies easier to access for overharvesting.

Ferrie was born in Cleveland, Ohio. A Roman Catholic, Ferrie attended St. Ignatius High School, John Carroll University, St. Mary's Seminary, where he studied for the priesthood, and Baldwin Wallace College. He next spent three years at the St. Charles Seminary in Carthagena, Ohio. He suffered from alopecia areata, a rare skin condition, which results in the loss of body hair and whose severity increases with age.

Madarosis is a condition that results in the loss of eyelashes, and sometimes eyebrows. The term "madarosis" is Greek for the word "madao" which means "to fall off." It originally was a disease of only losing eyelashes but it currently is the loss of both eyelashes and eyebrows. Eyebrows and eyelashes are both important in the prevention of bacteria and other foreign objects from entering the eye.

The purpose is to reduce the mechanical force on the sarcolemma as a result of muscle contraction. In addition to myoclonus dystonia, problems associated with a dysfunctional DAP complex include Duchenne muscular dystrophy. Upwards of 65 mutations of the SGCE gene are thought to cause myoclonus dystonia. The majority of the mutations lead to a truncated protein product that results in the loss-of-function of the epsilon sarcoglycan protein.

The second stated completed illegal move by the same player results in the loss of the game, unless the position is such that it is impossible for the opponent to win by any series of legal moves (e.g. if the opponent has a bare king) in which case the game is drawn. A move is completed when it has been made and the player has pressed the clock.

PRC1 is also recruited to the inactivated X chromosome in somatic cells in a highly dynamic, cell cycle-regulated manner. Recent study has indicated that knockdown of CULLIN3 or SPOP results in the loss of MACROH2A from the inactivated X chromosome, leading to reactivation even in the presence of methylation and deacetylase inhibitors. SPOP mutations have been implicated in endometrial cancer through the SPOP-CUL3-RBX1 E3 ubiquitin ligase complex.

GABAA receptor function is inhibited by zinc ions. The ions bind allosterically to the receptor, a mechanism that is critically dependent on the receptor subunit composition. De novo heterozygous missense mutations within a highly conserved region of the GABRB3 gene can decrease the peak current amplitudes of neurons or alter the kinetic properties of the channel. This results in the loss of the inhibitory properties of the receptor.

In order to obtain input data for PyClone, cell lysis is a required step to prepare bulk sample sequencing. This results in the loss of information on the complete set of mutations defining a clonal population. PyClone can distinguish and identify the frequency of different clonal populations but can not identify exact mutations defining these populations. Instead of clustering cells by mutational composition, PyClone clusters mutations that have similar cellular frequencies.

In Bomber Raid, the player controls a small "Freedom Fighter" aircraft able to fire different types of projectiles through five levels. The player starts with three lives and a limited number of cluster bombs. Any collision with either an enemy aircraft or enemy fire results in the loss of a life. One type of enemy, a strange disk like object with a green and red flashing center, drops a powerup when destroyed.

A particular cytokine gene encodes for IL-2, which influences T cell proliferation, survival, and differentiation. The absence of CD28 costimulation results in the loss of IL-2 production causing the T cells to be anergic. Additionally, CD28 ligation causes arginine-methylation for many proteins. CD28 also drives transcription within T cells and produce signals that lead to IL-2 production and Bcl-xL regulation, an antiapoptotic protein, which are essential for T cell survival.

When sea otters are removed from the ecosystem (for example, by human exploitation), urchin populations are released from predatory control and grow dramatically. This leads to increased herbivore pressure on local kelp stands. Deterioration of the kelp itself results in the loss of physical ecosystem structure and subsequently, the loss of other species associated with this habitat. In Alaskan kelp forest ecosystems, sea otters are the keystone species that mediates this trophic cascade.

Desymmetrization in stereochemistry is the modification of a molecule that results in the loss of one or more symmetry elements. A common application of this class of reactions involves the introduction of chirality.Willis, Michael C. "Enantioselective desymmetrization" Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry 1999, pp. 1765-1784. Formally, such conversions required the loss of an improper axis of rotation (mirror plane, center of inversion, rotation-reflection axis).

Once Siegfried has subdued Brunhild, Gunther takes Siegfried's place and takes Brunhild's virginity, which results in the loss of her superhuman strength. As a trophy, Siegfried takes Brunhild's ring and belt, which he later gives to Kriemhild. It is mentioned that Brunhild and Gunther have a son, whom they name Siegfried. Some years later, Brunhild, still disturbed by Siegfried's failure to behave as a vassal, convinces Gunther to invite Siegfried and Kriemhild to Worms.

Deforestation is often described as the changing of land from forested to non-forested by means both natural and unnatural. The relationship between deforestation and climate change is one of a positive feedback loop. The more trees that are removed equals larger effects of climate change which, in turn, results in the loss of more trees. In recent history, this process has been accelerated and amplified by humans in many different ways.

The game grants the player freedom to move around the convoy at will, but collision with any part of the fleet results in the loss of a life. Familiarity with the convoy layout is paramount to protecting it. Upon completion of a level the player is instructed to carefully dock with the largest ship in the fleet to re-fuel. Once successfully docked, bonus points are awarded for every dome left intact.

Another organism, Chiroptella geikiensis, a species of the chigger family Trombiculidae was discovered on specimens of this bat. Illustration of "Rhinolophus aurantius". Gould and H. C. Richter, 1863 The colony may desert a site if intruded upon by visitors, the species is noted as even more susceptible to human activities near their roosts than other bats. Direct threats include destruction of habitat by mining, clearing for agriculture and pastoralism that results in the loss of food resources.

Protesters linking arms to prevent San Francisco Sheriffs' deputies from evicting elderly tenants. August 4, 1977 Eviction is a cause of poverty, as well as a result of it. The loss of home often results in the loss of community connections, as well as children being forced into a new school. Possessions are routinely lost, as they are placed outside on the sidewalk or placed in storage that can only be accessed by paying a fee.

Chagas disease results in the loss of over 800,000 disability-adjusted life years each year. Chagas is endemic to 21 countries in continental Latin America: Argentina, Belize, Bolivia, Brazil, Chile, Colombia, Costa Rica, Ecuador, El Salvador, French Guiana, Guatemala, Guyana, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Suriname, Uruguay, and Venezuela. The endemic area ranges from the southern United States to northern Chile and Argentina, with Bolivia (6.1%), Argentina (3.6%), and Paraguay (2.1%) exhibiting the highest prevalence of the disease.

Decreases in skeletal muscle size and function have been reported since humans first began to explore space. Spaceflight results in the loss of lean body mass as determined by body composition measurements. Urinary amino acid and nitrogen excretion, both indirect measures of catabolism of lean body mass, are elevated during both brief and long spaceflights. Direct measurement of protein synthesis during spaceflight using 15N-glycine incorporation as a marker revealed an increase in whole-body protein synthesis rates.

He suggests that the mass media dilutes minority culture by representing the dominant culture as the most natural and normal. Lipsitz also proposes that capitalism turns historical traditions of minority groups into superficial icons and images in order to profit on their perception as "exotic" or different. Therefore, the commodification of these icons and images results in the loss of their original meaning. Minorities, according to Lipsitz, cannot fully assimilate nor can they completely separate themselves from dominant groups.

Some structures and upgrades become available only after the player achieves a certain "tech level". The UNSC can achieve multiple tech levels through the construction of reactors, with some actions requiring up to level four; the Covenant builds a single temple that allows three upgrades of tech level. The Covenant has one fewer tech level, and each upgrade is more expensive. Destruction of a temple results in the loss of all tech until the temple is rebuilt.

According to Vedic sages, when work becomes akin to a yajna (a worship ceremony), the effect of that work is transformed into apurva, that is, it becomes something unique, unprecedented and empowering. In contrast, anger clouds reason, which results in the loss of discrimination between right and wrong and virtue and vice. When the discriminating faculty is ruined, the person loses self-identity and the inner good perishes. With freedom from anger, a person reaches an apurva state.

Botrytis cinerea is a necrotrophic fungus that affects many plant species, although its most notable hosts may be wine grapes. In viticulture, it is commonly known as "botrytis bunch rot"; in horticulture, it is usually called "grey mould" or "gray mold". The fungus gives rise to two different kinds of infections on grapes. The first, grey rot, is the result of consistently wet or humid conditions, and typically results in the loss of the affected bunches.

Deep-fried foods cooked at certain temperatures can also contain acrylamide, a possible carcinogen. Additionally, fat degradation processes (lipid peroxidation) during deep frying results in the loss of nutritional value in deep-fried foods. Cooking oil that has been used for too long may in addition cause blood pressure elevation and vascular hypertrophy. Trans fats are used in shortenings for deep-frying in restaurants, as they can be used for longer than most conventional oils before becoming rancid.

David was king of Judah only but ends the conspiracy and is appointed king of Israel in Ishbaal's place. Some textual critics and biblical scholars suggest that David was actually responsible for the assassination and that his innocence was a later invention to legitimise his actions. Israel rebels against David and appoints David's son Absalom king. David is forced into exile east of the Jordan but eventually launches a successful counterattack, which results in the loss of Absalom.

Damage not only results in the loss of dreams but also of motivated behaviour. Transection or inhibition of the dopamine pathway also reduces some positive symptoms of schizophrenia, many of which have been likened to dream-like states. Drugs that block the system have anti- psychotic effects but also reduce excessive and vivid dreaming. Further evidence that dreaming can occur independently of REM sleep is found in the occurrence of nocturnal seizures during NREM that often present themselves as nightmares.

Following the collapse of Mr. Peanutbutter's house, he digs down to save everyone inside which results in the loss of his hands. He briefly has his hands replaced with gorilla feet and then lobster claws, but later receives hand transplants from a pedophile/murderer named Ernest Contralto. He is forced to re-run for governor following Todd's victory in the skiing race in which he is the only experienced politician. He eventually beats Jessica Biel following the revelation that she hates avocados.

Female Czechoslovak Wolfdogs tend to be more easily controllable, but both sexes often experience a stormy adolescence. The Czechoslovak Wolfdog is very playful, temperamental, and learns easily. However, it does not train spontaneously, the behavior of the Czechoslovak Wolfdog is strictly purposeful—it is necessary to find motivation for training. The most frequent cause of failure is usually the fact that the dog is tired out with long useless repetitions of the same exercise, which results in the loss of motivation.

The development of retinoblastoma can be explained by the two-hit model. According to the two-hit model, both alleles need to be affected, so two events are necessary for the retinal cell or cells to develop into tumors. The first mutational event can be inherited (germline or constitutional), which will then be present in all cells in the body. The second “hit” results in the loss of the remaining normal allele (gene) and occurs within a particular retinal cell.

The Striated, Spotted and Red- browed Pardalotes are widespread and common but their populations are decreasing due to habitat loss. Land clearing and commercial forestry in native eucalypt forests results in the loss of foraging habitat, nesting hollows and forest linkages essential for dispersal. The Forty-spotted Pardalote is listed as Endangered by the IUCN and under Australian legislation. The distribution of the Forty-spotted Pardalote is restricted to a narrow habitat range and the population is small and fragmented.

Since the Noongar are largely urbanised or concentrated in major regional towns, studies have shown that the direct economic impact of the Noongar community on the WA economy was estimated to range between five and seven hundred million dollars per year. Exit polls of tourists leaving Western Australia have consistently shown that "lack of contact with indigenous culture" has been their greatest regret. It has been estimated that this results in the loss of many millions of dollars worth of foregone tourist revenue.

After 9 to 12 seconds, the deoxygenated blood reaches the brain, and it results in the loss of consciousness. Exposure to vacuum for up to 30 seconds is unlikely to cause permanent physical damage. Animal experiments show that rapid and complete recovery is normal for exposures shorter than 90 seconds, while longer full-body exposures are fatal and resuscitation has never been successful. There is only a limited amount of data available from human accidents, but it is consistent with animal data.

On reaching the Swan Coastal Plain, they encounter two obstacles: firstly, the high permeability of the soil results in the loss of much water. Much flow is lost, and some watercourses simply cease to flow, for example, Wungong Brook, Cardup Brook, and Manjedal Brook. Secondly, the sequence of north-to-south-oriented dunes create obstacles to further westerly flow. Many watercourses turn at right angles and flow south or north along the dune swales, and in some cases this allows multiple watercourses to coalesce.

This increases the ability to remove waste products, like lactic acid, out of the muscles in order to not impair muscle function. Once moved out of muscles, lactic acid can be used by other muscles or body tissues as a source of energy, or transported to the liver where it is converted back to pyruvate. In addition to increasing the level of lactic acid, strenuous exercise results in the loss of potassium ions in muscle. This may facilitate the recovery of muscle function by protecting against fatigue .

Kalagni meets an old acquaintance in the caravan and chats mysteriously with him. On their way to Jabalpur in the jungle, they are cornered and attacked by a herd of elephants, which results in the loss of the second carriage. To escape from the herd, Banks drives the Steam House into Lake Puturia. All the food and provisions are lost with the second carriage and after some time, the fuel is exhausted, resulting in the Steam House floating in the middle of the lake.

From 1980–2012 the mean cumulative mass loss of glaciers reporting mass balance to the World Glacier Monitoring Service is −16 m. This includes 23 consecutive years of negative mass balances. Chart of annual and cumulative glacier mass balance from World Glacier Monitoring Service Data A glacier with a sustained negative balance is out of equilibrium and will retreat, while one with a sustained positive balance is out of equilibrium and will advance. Glacier retreat results in the loss of the low elevation region of the glacier.

Mice lacking FEZF1 had no prethalamus and had a smaller thalamus. A loss of function mutation in FEZF1 causes Kallmann Syndrome. As axons are developing and migrating in the early embryo, FEZF1 allows the axons of olfactory neurons to attach to the central nervous system in the mice model. During neural development, GnRH neurons migrate through one of these olfactory axon pathways, and the loss of function of FEZF1 therefore results in the loss of GnRH neurons in the brain, the hallmark of Kallmann Syndrome.

Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease, is a neurodegenerative disease that results in the loss of motor neurons that control voluntary muscles. Some also use the term motor neuron disease for a group of conditions of which ALS is the most common. ALS is characterized by stiff muscles, muscle twitching, and gradually worsening weakness due to muscles decreasing in size. It may begin with weakness in the arms or legs, or with difficulty speaking or swallowing.

Coins are neither gained nor lost from these spaces, and coins are only earned by winning mini- games. The winner of Mini-Game Stadium is determined by whoever accumulates the highest number of coins by the completion of the allotted turns. In the Mini-Game Coaster, one human player must play through each mini-game. The player has three lives and progresses through a world map with the completion of each mini-game, while losing a mini-game results in the loss of a life.

People can become entirely edentulous (without teeth) for many reasons, the most prevalent being removal due to dental disease, which typically relates to oral flora control, i.e., periodontal disease and tooth decay. Other reasons include pregnancy, tooth developmental defects caused by severe malnutrition, genetic defects such as dentinogenesis imperfecta, trauma, or drug use. Periodontitis is defined as an inflammatory lesion mediated by host-pathogen interaction that results in the loss of connective tissue fibre attachment to the root surface and ultimately to the alveolar bone.

In a first group of methods, initiation of second-strand synthesis takes place within the sequence of the first strand. However, the digestion of the 3' end of the first strand is required and therefore results in the loss of the sequences corresponding to the 5'end of the mRNA. In a second group of methods, initiation of second-strand synthesis takes place outside the sequence of the first strand. This group of methods does not require digestion of the 3' end of the first strand.

As first discovered in 1882, pyroglutamic acid can be formed by heating glutamic acid at 180 °C, which results in the loss of a molecule of water. In living cells, it is derived from glutathione through the action of an enzyme, γ-glutamyl cyclotransferase. Pyroglutamic acid may function in glutamate storage, and acts to oppose the action of glutamate, including in the brain. It also acts on the brain's cholinergic system; Amyloid β containing pyroglutamic acid is increased in Alzheimer's disease; this may be part of the disease process.

Getting hit or firing upon a civilian results in the loss of one of three lives and an appropriate sequence involving a gravedigger. There is one load/save slot and a second player can be introduced at the start of the game. The point, or "cash", bonus for completing a stage is higher if the boss is taken alive, by means of shooting the gun out of his hand before he can fire. Depending on who was captured alive, spared bosses may come back and try to either bribe or shoot the player character.

Lenz,Lenz, H.: Raumsinnstorung bei Hirnverletzungen, Deutsche Ztschr. Nervenh. 157:22-64, 1944. and McFie and associatesMcFie, J.; Piercy, M. F., and Zangwill, O. L.: Visuo-Spatial Agnosia Associated with Lesions of the Right Cerebral Hemisphere, Brain 75:433-471, 1952 proposed that the brain's right hemisphere controls a specific function in spatial perception, explaining why damage to the parieto-occipital lobe of the right hemisphere results in the loss of spatial perception. In his article, Denny- Brown alternately proposes that lesions of the parieto-occipital lobe cause errors in spatial summation, not spatial perception.

Fighters, with pilots and secondary armaments potentially attached, move among the nav points, fighting with each other and attacking the enemy carrier. During combat, either player may play "Maneuver" cards to fortify their fighters (assuming the targeted craft has a high enough Maneuver statistic) or "Battle Damage" cards to cripple their enemies; both have Power Point costs. Attacks are then resolved by comparison of the aggressor's Attack value with the defender's Defense value (with Support values from allied ships augmenting as appropriate). Each card lost results in the loss of one Power Point as well.

For example, dementia, a chronic and progressive disease that attacks the brain can induce memory loss and cause a decrease in rational thinking, almost always results in the loss of autonomy. Psychiatrists and clinical psychologists are often asked to evaluate a patient's capacity for making life-and-death decisions at the end of life. Persons with a psychiatric condition such as delirium or clinical depression may lack capacity to make end-of-life decisions. For these persons, a request to refuse treatment may be taken in the context of their condition.

Glacier retreat results in the loss of the low-elevation region of the glacier. Since higher elevations are cooler, the disappearance of the lowest portion decreases overall ablation, thereby increasing mass balance and potentially reestablishing equilibrium. If the mass balance of a significant portion of the accumulation zone of the glacier is negative, it is in disequilibrium with the climate and will melt away without a colder climate and/or an increase in frozen precipitation. Methods for measuring retreat include staking terminus location, global positioning mapping, aerial mapping and laser altimetry.

David is eventually cleared but the damage to the marriage is done after Liljana begins to think he really is guilty. David is devastated when he finds that Paul and Liljana have been having an affair. He tries to run Paul down with his car one afternoon at Lassiter's. After Paul is hospitalised after a bad business deal, which results in the loss of a leg, David, working as a salvation army volunteer, encounters him in the hospital and is goaded by Paul with the chance to get him out of the Bishops' life forever.

CTCF binds to the unmethylated maternal ICR region but not the methylated paternal ICR region. ICR is a shared control region of Ifg2 and H19 that, when deleted, results in the loss of imprinting of these genes. CTCF then binds another region of the chromosome, creating a loop where Igf2 is blocked from transcription, but H19 is not, resulting in the maternal chromosome expressing H19 but not Igf2. CTCF has been shown to directly interact with Suz12, a subunit of PRC2, in order to silence the Ifg2 promoter region through hypermethylation.

However, he is unable to make it to the fair due to getting lost in the woods. After going down a path that results in the loss of his horse and cart, and being attacked and nearly killed by a pack of rabid wolves, he winds up at the gate of a dark castle. When he enters the castle to stay for the night, he ends up being locked up by the Beast, the castle's master. Belle learns of what happened and goes to the castle, attempting to release her father.

This has resulted in the county having one of the highest unemployment rates annually in the state of Tennessee. The lack of jobs often results in the loss of educated young people who have limited opportunities locally. SR 52 has been upgraded to a 4-lane divided highway as part of the Corridor J project, which connects to I-40 in Cookeville, and work continues on developing a new industrial park within the Celina city limits. It is hoped this industrial park will help attract more jobs to the county. .

These newly synthesized membranes do not come from the thylakoids, but rather from vesicles generated from the inner membrane of the plastid. The most obvious biochemical change would be the downregulation of photosynthetic gene expression which results in the loss of chlorophyll and stops photosynthetic activity. In oranges, the synthesis of carotenoids and the disappearance of chlorophyll causes the color of the fruit to change from green to yellow. The orange color is often added artificially—light yellow-orange is the natural color created by the actual chromoplasts.

Their relationship is coloured by Maggie's desire to recapture the unconditional love of her father before his death. Tom's pragmatic and reserved nature clashes with Maggie's idealism and fervor for intellectual gains and experience. Various family crises, including bankruptcy, Mr Tulliver's rancorous relationship with Philip Wakem's father, which results in the loss of the mill and Mr Tulliver's untimely death, intensify Tom's and Maggie's differences and highlight their love for each other. To help his father repay his debts, Tom leaves school to enter a life of the business.

The decreased length of the open reading frame results in the loss of 2 prenylation sites and 1 amidation site. In human CERK, a retinoic acid response element (RARE)-like exists between -40bp and -28bp and contains the sequence: TCCCCG C CGCCCG. RARE-like plays a role in transcription regulation of CERK. It is suspected that in the presence of all-trans retinoic acid (ATRA), chicken ovalbumin upstream promoter transcription factor I (COUP- TFI), retinoic acid receptor (RARα), retinoid X receptor (RXRα) bind the RARE- like of CERK in 5H-SY5Y cells.

A problem with using reverberatory furnaces for cupellation is that the zinc oxidizes first, forming a crust across the top of the molten material. This crust prevents the penetration of oxygen to the rest of the material, and so it has to be manually broken up and removed using a rabble bar. This is both labor-intensive and also results in the loss of some of the silver. Similarly, the oxidized lead slag has to be removed when it forms to maintain the operation, and its removal also results in loss of silver.

Courses are composed of numerous tiles, which are suspended high above ground. The ball must be bounced past walls and over enemies; coming into contact with either, or plummeting over the edge of the course, results in the loss of one of the player's seven lives. Courses feature power squares, which push the tennis ball forward and allow longer jumps, these must be utilized to complete the course. Power squares are also used to enable the tennis ball to reach mystery spaces, tiles with question marks, which contain extra lives and bonus jumps which are used on bonus screens.

Otter enthusiastically left for America, only to find that the reality of being a Chinese immigrant meant working in the brutal cold and other awful conditions. Otter is filled with disgust and undertakes the seemingly impossible task of climbing the Tiger, the mountain which for so long has kept his people working in bitter conditions, ascending above the cloud layer to prevent an avalanche. Which results in the loss of his beloved Uncle. Taken aback by his loss, Otter is determined to finish what his Uncle started, even if it means withstanding the bitter cold for the rest of his life.

The function of this depressive adaptation is to prevent the loser from suffering further defeat in a conflict. In the face of defeat, a behavioural process swings into action which causes the individual to cease competing and reduce his ambitions. This process is involuntary and results in the loss of energy, depressed mood, sleep disturbance, poor appetite, and loss of confidence, which are typical characteristics of depression. The outward symptoms of depression (facial expressions, constant crying, etc.) signal to others that the loser is not fit to compete, and they also discourage others from attempting to restore the loser's rank.

On 8 March 2009 the satellite suffered a loss of communication with Data Processing Unit No. 1, processing data from one of the two photo- detector chains on the spacecraft. Science operations resumed early April with Data Processing Unit No. 1 offline while Data Processing Unit No. 2 operating normally. The loss of photo-detector chain number 1 results in the loss of one CCD dedicated to asteroseismology and one CCD dedicated to planet detection. The field of view of the satellite is thus reduced by 50%, but without any degradation of the quality of the observations.

The stunts that can be performed are relatively simple, mostly only involving jumping in the air and rotating about a given axis in 3D space. The idea is to be able to perform these stunts quickly in tight situations while landing the unicycle on its wheel to avoid wiping out, which results in the loss of accumulated speed. The game features nine tours of five tracks each (two race, two circuit, one stunt) for a total of 45. Beating each of the first eight tours requires defeating computer-controlled opponents for each of bronze, silver, and gold ranks.

Mount Cleveland is located from the western end of the Aleutian Arc, a long volcanic chain extending off the coast of Alaska. Containing over 75 volcanoes, this volcanic arc occurs above the subduction zone where the Pacific Plate plunges under the North American plate. As the plate moves deeper into the earth, the increasing pressure results in the loss of volatiles, certain elements and compounds with low boiling points, from various hydrous minerals. One of these compounds is water; its addition to the mantle wedge formed between the subducting and overriding plates lowers the melting point enough to allow magma to form.

During biostasy, abundant and regular precipitation induces strong pedogenesis characterized by chemical alteration of parent material and intensified eluviation and illuviation of soil minerals within the surface soil and subsoil layers (the solum). These processes contribute to the formation of eluvial and argillic horizons and an increased concentration of iron oxides, aluminum oxides, and other sesquioxides in the subsoil. Climatic conditions favor a vegetative cover which protects the soil from physical erosion but abundant rainfall results in the loss of mineral ions and increased concentration of those minerals in receiving bodies of water. Abundant marine calcium results in limestone formation.

On the other hand, video input in excess of 1.1 volt results in the loss of the carrier level and this tends to shut down the transmitter. For this reason a white clipper circuit is used to strictly limit the maximum amplitude of the video waveform at the transmitter. For recording and general use the white clipper is used to limit the maximum excursion of the signal. For recording this prevents overmodulation on analogue systems which tends to corrupt adjacent tracks in helical scanning; while on digital systems the peak signal amplitude is an absolute numerical value and cannot be exceeded.

Supreme Commander, like its spiritual predecessor, begins with the player solely possessing a single, irreplaceable construction unit called the "Armored Command Unit," or ACU, the titular Supreme Commander. Normally the loss of this unit results in the loss of the game (Skirmish missions can be set for a variety of victory conditions). These mech suits are designed to be transported through quantum gateways across the galaxy and contain all the materials and blueprints necessary to create a 37th-century army from a planet's native resources in hours. All standard units except Commanders and summoned Support Commanders (sACU) are self-sufficient robots.

As mentioned, irradiation of the co-factor with UV light results in the loss of CO and Fe. In addition the 542 Da compound can be further degraded by a phosphodiesterase (which specifically cleaves phosphate bonds). Hydrolysis of the phosphate bonds generates the ribonucleotide guanine mono-phosphate and a modified 2-pyridone. On the basis of spectroscopic characterization, Shima et al. have proposed a structure for this organic cofactor (minus the iron atom and CO molecules) as shown: Hmd Catalyzed Reaction Although the mechanism by which Hmd acts is unknown, the iron-containing cofactor is in part responsible for the catalytic activity.

Prior to the show, contestants are asked to answer a series of questions while connected to a polygraph, but were not informed of the results. During the show, each contestant is again asked up to 21 of the questions they were asked offscreen. A voice-over, or occasionally the host, announced whether the answer is "true" or "false", based on the result of the polygraph test before the show. The contestant may continue after certain milestones and keep the money they have won so far; giving an answer deemed "false" results in the loss of all the money.

However, it has been suggested that the tau mutation is a gain-of-function mutation, leading to increased phosphorylation of certain PER sites, thereby increasing the rate of PER degradation and shortening the circadian period. The CK1ε-tau mutation in hamsters was the first full description of a mammalian circadian mutant. In humans, mutations affecting the PER2 phosphorylation site of the CK1ε and/or CK1δ gene result in Familial Advanced Sleep Phase Syndrome (FASPS). This mutation, S662G, which results in the loss of a single phosphate acceptor site on PER2, prevents CK1ε protein from binding to PER and leads to an unusually short circadian period.

The king in the text, states K. V. Nagarajan, is assigned the "role of producing, acquiring, conserving, and dispensing wealth". The king's duty is to provide a just rule, be impartial and have courage in protecting his subjects and in meting out justice and punishment. The text supports death penalty for the wicked in the book of poruḷ, but does so only after emphasizing non-killing as every individual's personal virtue in the book of aṟam. The Kural cautions against tyranny, appeasement and oppression, with the suggestion that such royal behavior causes natural disasters, depletes the state's wealth and ultimately results in the loss of power and prosperity.

Vancomycin Six different types of vancomycin resistance are shown by enterococcus: Van-A, Van-B, Van-C, Van-D, Van-E and Van-G. The significance is that Van-A VRE is resistant to both vancomycin and teicoplanin, Van-B VRE is resistant to vancomycin but susceptible to teicoplanin, and Van-C is only partly resistant to vancomycin. The mechanism of resistance to vancomycin found in enterococcus involves the alteration of the peptidoglycan synthesis pathway. The D-alanyl- D-lactate variation results in the loss of one hydrogen-bonding interaction (four, as opposed to five for D-alanyl-D-alanine) being possible between vancomycin and the peptide.

Escape from Tarkov is a multiplayer first-person shooter video game in development by Battlestate Games for Windows. A closed alpha test of the game was first made available to select users on August 4, 2016, followed by a closed beta which has been running since July 2017. The game is set in the fictional Norvinsk region in Northwest Russia, where a war is taking place between two private military companies (United Security and BEAR). Players join matches in which they fight other players for loot and aim to survive and escape - dying results in the loss of almost all items the player used and found during that game.

Those with social- emotional agnosia have difficulty discerning the emotional meaning and significance behind objects, which causes a loss of fondness and familiarity. Bilateral amygdala damage has also been associated with social unresponsiveness, leading to an avoidance of social interactions and a preference for isolation from their own species. Evidence suggests that damage to the amygdala and the limbic system (specifically the amygdala-hypothalamus pathway) results in the loss of the core ability to recognize and interpret the mental states of others, a vital ability in social interactions. The amygdala evokes highly personal emotional memories and the loss of this function causes hypo-emotionality, a general lack of emotion when presented with different stimuli.

Natural calamities, such as floods, tropical cyclones, tornadoes, and tidal bores—destructive waves or floods caused by flood tides rushing up estuaries—ravage the country, particularly the coastal belt, almost every year. Between 1947 and 1988, 13 severe cyclones hit Bangladesh, causing enormous loss of life and property. In May 1985, for example, a severe cyclonic storm packing winds and waves high swept into southeastern and southern Bangladesh, killing more than 11,000 persons, damaging more than 94,000 houses, killing some 135,000 head of livestock, and damaging nearly of critically needed embankments. Flooding after the 1991 Bangladesh cyclone Annual monsoon flooding results in the loss of human life, damage to property and communication systems, and a shortage of drinking water, which leads to the spread of disease.

The Dublin Declaration on Maternal Health, signed in 2012, prioritizes fetal right to life by noting that "there is a fundamental difference between abortion, and necessary medical treatments that are carried out to save the life of the mother, even if such treatment results in the loss of life of her unborn child". Several organizations, such as World Health Organization (WHO) and Human Rights Watch prioritize women's reproductive rights over fetal rights. Under European law, fetus is generally regarded as an in utero part of the mother and thus its rights are held by the mother. The European Court of Human Rights opined that the right to life does not extend to fetuses under Article 2 of the European Convention on Human Rights (ECHR).

No consensus can be made on his stated desire to live out his days on a planet of humans, with doubts remaining as to his actual intent. Meanwhile, the remains of the Realm are still causing difficulties, which results in the loss of a crew member while he and Sulu (Grant Imahara) are removing debris from the hull of the Enterprise. Scotty comes up with a method to remove the remains, using an electromagnetic pulse, but while doing so, Uhura (Kim Stinger) is gravely wounded from an electrostatic shock, and dies while in sickbay. Apollo, witnessing this, gets up from his bed and places his hands over Uhura, and despite a warning from Spock to conserve his own energy, is able to return Uhura to life.

However, interfering signals can be observed due to side reactions of the matrix with the sample, such as in the case of the matrix interacting with alkali metal ions which can impair the analysis of the spectra. Typically the amount of salt in the matrix only becomes a problem in very high concentrations, such as 1 molar. The problem of having too high a concentration of salt in the sample can be solved by first running the solution through liquid chromatography to help purify the sample, but this method is time consuming and results in the loss of some of the sample to be analyzed. Another method is focused on purification once the sample solution is deposited onto the sample probe.

In a series of stages, the player must shoot enemies before they fire, avoid shooting innocent bystanders, and reload each time their six-round revolver is depleted of bullets. Shooting a bystander or getting hit by a gunfighter results in the loss of one life out of three and is followed by a clip showing the town doctor commenting on the player's actions. However, this traditional light gun shooter gameplay is interspersed with "showdowns", which are fast draw duels that play the same as American Laser Games's later release Fast Draw Showdown. The arcade version is equipped with a specialized light gun which can detect whether or not the player had properly lowered the light gun at the beginning of the duel.

In advance of the 2016 NASCAR Sprint Cup Series season, the RTA played an integral role in forming an agreement between NASCAR and the various NASCAR Cup Series competitors on a charter system which would guarantee full-time license holders automatic entrance into every race of the season for nine years. Charters which are transferable were granted to full-time Cup Series teams that had been active in a full-time capacity since at least the 2013 NASCAR Sprint Cup Series season. There are a total of 36 charters, and a new total starting field in each race of 40 providing four "open" spots on the weekly race grid. Failure to field a car results in the loss of that charter.

The prevalent theory which explains the start of complex societies is the pressure exuded by warfare or a method to organize a population of approximately more than 150. Warfare contribution to establishing complex societies by creating pressure for comprehension between groups which strengthens the cooperation in groups, it improves the organization of the groups structure , and pushes the desire to grow the population of the group. The growth of population results in the loss of person to person interaction which creates a need for a system to keep track the interaction between the leads of the group. The groups would then create symbols of either language, clothing or ideology to identify who belongs to the group and where are their position in the society.

In mature individuals, the culms in young plants grow taller and wider in diameter as the general plant reaches maturity, but once the individual culm stops growing it will not grow again. P. edulis also flowers and produces seed, and it does so every half century or so, but it has a sporadic flowering nature rather than the synchronous blooming seen in some other bamboo species. The seeds fall from the mature culms in the hundreds of thousands and are quick to germinate. Mice, field rats and other rodents take notice of the bounty of seed, this results in the loss of many of the seeds, but within a few weeks the surviving few seeds would have germinated (see Predator satiation).

Comparison of brain tissue between healthy individual and Alzheimer's disease patient, demonstrating extent of neuronal death Alzheimer's disease (AD) is a chronic neurodegenerative disease that results in the loss of neurons and synapses in the cerebral cortex and certain subcortical structures, resulting in gross atrophy of the temporal lobe, parietal lobe, and parts of the frontal cortex and cingulate gyrus. AD pathology is primarily characterized by the presence of senile plaques and neurofibrillary tangles. Plaques are made up of small peptides, typically 39–43 amino acids in length, called beta-amyloid (also written as A-beta or Aβ). Beta-amyloid is a fragment from a larger protein called amyloid precursor protein (APP), a transmembrane protein that penetrates through the neuron's membrane.

With the rise of tourism and the subsequent influx in economic opportunity in Kenya, also comes the gradual degradation of its environment and the very ecosystems that are supposedly preserved as the tourists’ main attractions. The very construction of wildlife preservations and reserves as a means to conserve environmental biodiversity is, in and of itself, somewhat of a contradiction as it involves the commercial destruction of that unspoiled area to exist. Deforestation is a hugely negative impact suffered in the building process of wildlife areas and the various accommodations needed for tourists, such as lodging, campsites, roads for safari tours, outhouses, firewood, etc. This deforestation not only results in the loss of native flora, but it also causes a dramatic loss of habitat for animal species, resulting in a number of complications.

Public disclosure is any non-confidential communication which an inventor or invention owner makes available to one or more members of the public, revealing the existence of the invention and enabling an appropriately experienced individual ("person having ordinary skill in the art") to reproduce the invention. In the U.S., public disclosure of an invention results in the loss of patentability of the invention after a period of one year. In other countries, public disclosure may result in the immediate loss of invention patentability unless a patent application has already been filed, and disclosure may be considered to include oral as well as written communication. establishes various statutory bars to invention patentability with regard to invention novelty; these explicit bars preclude patentability as exceptions to a general underlying entitlement.

However, "common" and "uncommon" are also sometimes used to describe levels of abundance, with a common species being less abundant than an abundant species, while an uncommon species is more abundant than a rare species. Common species are frequently regarded as being at low risk of extinction simply because they exist in large numbers, and hence their conservation status is often overlooked. While this is broadly logical, there are several cases of once common species being driven to extinction such as the passenger pigeon and the Rocky Mountain locust, which numbered in the billions and trillions respectively before their demise. Moreover, a small proportional decline in a common species results in the loss of a large number of individuals, and the contribution to ecosystem function that those individuals represented.

The hydrogen on the water has a partial positive charge, which stabilizes the tetrahedral oxyanion intermediate. What will then occur is that the tetrahedral intermediate will collapse and lead to reformation of the carbonyl bond which results in the loss of the leaving group- that would be the P site ribose ring with the tRNA attached to it. With the release of the leaving group, the proton will be abstracted from the water which will lead to abstracting the proton from the two prime hydroxyl groups and the lone pairs will abstract the proton from the new amine of the amino acid. After the mechanism is complete, a non-acylated tRNA will remain in the P site and the entire growing polypeptide chain in addition to the extra amino acids are all attached in an ester linkage to the three prime hydroxyl groups of the tRNA in the A site.

Eteläsatama, the new site of the proposed museum, seen from the bay In September 2013, the Guggenheim Foundation advanced a revised proposal under which the museum would focus on Nordic and international architecture and design in the context of other forms of modern and contemporary art. Educational programs at the museum would provide opportunities for children and adults to expand their experience of the visual arts. The project's architect was to be chosen through an international competition."Guggenheim Foundation proposes architectural competition for Helsinki museum", YLE, September 24, 2013"Guggenheim Foundation presents a new proposal for a Guggenheim Helsinki", Art Daily, September 2013, accessed February 12, 2014 The proposal eliminates the controversial proposed merger with Helsinki Art Museum, although this results in the loss of the 700,000 euro government subsidy, and the new museum is envisioned to gradually build up a permanent collection from parts of its exhibitions.