The prostatic fluid is expelled in the first part of ejaculate, together with most of the sperm, because of the action of smooth muscle tissue within the prostate. In comparison with the few spermatozoa expelled together with mainly seminal vesicular fluid, those in prostatic fluid have better motility, longer survival, and better protection of genetic material. Disorders of the prostate include enlargement, inflammation, infection, and cancer. The word prostate comes from Ancient Greek προστάτης, prostátēs, meaning "one who stands before", "protector", "guardian", with the term originally used to describe the seminal vesicles.
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Esmail, S. (2010). HECOL 211 Human Sexuality Lecture Manual 2010. Department of Human Ecology, University of Alberta, Edmonton, AB. Seminal fluid continues down the ejaculatory duct into the prostate gland, where an alkaline prostatic fluid is added. This addition provides the texture and odor associated with semen.
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In vitro, approximately 32% of the drug in plasma is protein bound. Floxin is widely distributed to body tissues. Ofloxacin has been detected in blister fluid, cervix, lung tissue, ovary, prostatic fluid, prostatic tissue, skin, and sputum. Pyridobenzoxazine ring appears to decrease the extent of parent compound metabolism.
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The prostate is the only accessory gland that occurs in male dogs. Dogs can produce in one hour as much prostatic fluid as a human can in a day. They excrete this fluid along with their urine to mark their territory. Additionally, dogs are the only species apart from humans seen to have a significant incidence of prostate cancer.
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Ejaculation in boars is stimulated when the spiral- shaped penis interlocks with the female's cervix. A mature boar can produce of semen during one ejaculation. In llamas and alpacas, ejaculation occurs continuously during copulation. The semen of male dogs is ejaculated in three separate phases. The last phase of a male canine’s ejaculation occurs during the copulatory tie, and contains mostly prostatic fluid.
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It is surrounded by a fibromuscular capsule and contains glandular tissue as well as connective tissue. The prostate glands produce and contain fluid that forms part of semen, the substance that is emitted during ejaculation as part of the male sexual response. This prostatic fluid is slightly alkaline, milky or white in appearance. The alkalinity of semen helps neutralize the acidity of the vaginal tract, prolonging the lifespan of sperm.
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There have been contradictory findings regarding the penetrability of nitrofurantoin , quinolones (ciprofloxacin, levofloxacin), sulfas (Bactrim, Septra), doxycycline and macrolides (erythromycin, clarithromycin). This is particularly true for gram-positive infections. In a review of multiple studies, levofloxacin was found to reach prostatic fluid concentrations 5.5 times higher than ciprofloxacin, indicating a greater ability to penetrate the prostate. Clinical success rates with oral antibiotics can reach 70% to 90% at 6 months, although trials comparing them with placebo or no treatment do not exist.
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The alkalinity of the prostatic fluid serves to neutralize the acidity of the female vaginal tract in order to prolong the survival of sperm in this harsh environment. Semen is now a fructose-rich, alkaline fluid containing sperm as it enters the bulbourethral glands below the prostate. The bulbourethral glands secrete a small amount of clear fluid into the urethra before the ejaculate is expelled. The functions of this fluid are not entirely known but are suggested to aid in lubricating the male urethra in preparation for the semen during ejaculation.
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The dog's penis enlarges inside the vagina, thereby preventing its withdrawal; this is sometimes known as the "tie" or "copulatory lock". The male dog rapidly thrust into the female for 1–2 minutes then dismounts with the erect penis still inside the vagina, and turns to stand rear-end to rear-end with the female dog for up to 30 to 40 minutes; the penis is twisted 180 degrees in a lateral plane. During this time, prostatic fluid is ejaculated. The female dog can bear another litter within 8 months of the previous one.
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Erect bulbus glandis (1) in a Labrador Retriever The bulbus glandis (also called a bulb or knot) is an erectile tissue structure on the penis of canid mammals. During mating, immediately before ejaculation the tissues swell up to lock (tie) the male's penis inside the female. The locking is completed by circular muscles just inside the female's vagina; this is called "the knot" tightening thus preventing the male from withdrawing. The circular muscles also contract intermittently, which has the effect of stimulating ejaculation of sperm, followed by prostatic fluid, as well as maintaining the swelling of the penis and therefore the tie, for some time.
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In women, the labia and clitoris may become engorged and there may be a discharge of blood from the vagina while in men, "a more or less complete state of erection of the penis, with discharge of urine, mucus or prostatic fluid is a frequent occurrence ... present in one case in three." Other causes of death may also result in these effects, including fatal gunshots to the head, damage to major blood vessels, and violent death by poisoning. A postmortem priapism is an indicator that death was likely swift and violent. In a case reported from Thailand, an excess of sildenafil (Viagra) was thought to be cause of a death erection in a 64-year-old man.
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