192 Sentences With "oxygen deprivation" | Random Sentence Generator

Oxygen deprivation causes the brain to start breaking itself down, leading to permanent damage.

As few as five minutes of oxygen deprivation can cause permanent brain damage or death.

Mushrooms basically exhale carbon dioxide as they grow; you're probably experiencing a little oxygen deprivation.

They cited a rash of incidents in which pilots appeared to suffer from oxygen deprivation.

Or it could be the combination of oxygen deprivation and a specific toxic effect of fentanyl.

Oxygen deprivation of this kind occurs when waters are overloaded with sewage, fertilizers, and other nutrients.

"We wanted to test systematically just how much oxygen deprivation these animals can stand," he said.

"Perhaps even feeding the brain fructose during this period of oxygen deprivation could help," Lewin said.

Pauly noted that oxygen deprivation is already killing fish in the United States and around the world.

To learn more about how Čolak overrode his instincts to master the art of oxygen deprivation, watch above.

They cited a rash of incidents in which pilots appeared to suffer from oxygen deprivation, known as hypoxia.

What the naked mole rat can do is up-regulate its fructose pathway when it goes into oxygen deprivation.

Such hypoxia, or oxygen deprivation, results in lower production of serotonin by the brain, which can lead to depression.

The researchers learned that spaceflight is associated with oxygen-deprivation stress, increased inflammation and dramatic nutrient shifts that affect gene expression.

This supercharging then might make the effects of any oxygen deprivation to the area caused by an overdose all the more damaging.

We make it up one of the mid-size dunes and decide to head back down before G. dies from oxygen deprivation.

Autopsies had concluded that the provisional cause of death was a combination of hypoxia - oxygen deprivation - and hyperthermia - overheating - in an enclosed space.

The brain is highly sensitive to lack of oxygen; permanent brain damage sets in after four minutes of oxygen deprivation in most situations.

Controlled atmosphere stunning, on the other hand, uses gas to knock the birds out before they die of oxygen deprivation or later bleed-out.

And stroke makes the brain vulnerable even after the initial event: Oxygen deprivation causes a severe drop in brain pH, leading to damaged neurons.

Nik, who is training with wind machines and an oxygen-deprivation mask, said the volcanic gases could pose a real threat to the wire.

A cease-fire with Pakistan has been in place since 2003, but soldiers live in constant danger of frostbite, oxygen deprivation, hidden crevasses and avalanches.

A baby of an HIV+ mom might get the correct dose of antiretrovirals, only to suffer long-term disability or die due to oxygen deprivation.

Rescuers scrambled to get to Matilda -- but by the time they reached her, she was in bad shape ... suffering from oxygen deprivation and brain damage.

It's definitely a bad sign if your lips turn blue, but you probably won't die from oxygen deprivation by sucking on a whipped-cream can.

The Air Force suspended the F-35A flights on June 85033 after five incidents since May 2 in which pilots experienced symptoms similar to oxygen deprivation.

More specifically, the device helps pilots recognize oxygen deprivation in a controlled environment so they can properly execute emergency procedures if a situation develops while airborne.

Autopsies concluded that the provisional cause of death of the 39 people was a combination of hypoxia - oxygen deprivation - and hyperthermia - overheating - in an enclosed space.

The Air Force in June temporarily grounded a squadron of F-35 fighter jets in Arizona to figure out why five pilots suffered from oxygen deprivation.

The researchers looked at a composite of adverse outcomes for the baby, including stillbirth, neonatal death, brain hemorrhage, oxygen deprivation, troubled breathing, convulsions and required ventilation.

The 29-year-old hit up BlueStreak Sports Training facility in Stamford, CT yesterday -- and grinded out a pretty intense workout complete with an oxygen deprivation mask.

She was drawn to videos by Andrew Moulden, a Canadian neuroscientist who claimed that vaccines cause autism by triggering oxygen deprivation or "mini strokes" in the brain.

Oxygen deprivation The open ocean is also losing its oxygen, between 0.5-3.3% between 21003 and 2010, the IPCC report found, and it's expected to get worse.

I won't give too much away (you'll have to watch the video), but it involves meeting with a neurosurgeon, researching pearl divers and some major oxygen deprivation.

The cause was brain damage from oxygen deprivation, said her husband of only three months, Mattias Hargin, a Swedish Alpine World Cup skier and her high school sweetheart.

There are many known causes, including a wide range of genetic disorders such as Down syndrome, as well as oxygen deprivation to the fetus, cytomegalovirus and severe fetal alcohol syndrome.

And in October a Navy instructor and a student died when their T-45 crashed in east Tennessee, though it is not yet known whether oxygen deprivation was a factor.

Although she and another audience member ran to him and loosened the noose, the actor remained in a coma until Friday when he was pronounced brain dead after severe oxygen deprivation.

The 56th Fighter Wing cancelled local flying operations for its F-35A Lightning II fighters after five incidents since May 2 where pilots experienced symptoms similar to hypoxia, or oxygen deprivation.

The Air Force's temporary grounding of a squadron of F-28503 fighter jets in Arizona has been extended as analysts try to figure out why five pilots suffered from oxygen deprivation.

Following a rash of incidents during which pilots appeared to suffer from oxygen deprivation, the Navy will install new oxygen-level monitoring systems on all T-2628 training jets by February. Sen.

Washington (CNN)An F-35 fighter wing will remain grounded as the service works to identify the cause of five incidents where pilots suffered from oxygen deprivation problems, the Air Force said Monday.

The Air Force has "temporarily" grounded a squadron of F-35s fighter jets at Luke Air Force Base in Arizona after five pilots reported symptoms consistent with oxygen deprivation, the service said Friday.

Read: The dangers of oxygen deprivation on Everest The end products will be methane gas, which can be used for cooking or lighting, and effluent that can be used as fertilizer for crops.

The base canceled local flying operations for its F-35A Lightning II aircraft due to five incidents in which pilots experienced symptoms resembling hypoxia, or oxygen deprivation, Graff said on Friday at the Pentagon.

So by understanding this mechanism, we might be able to help someone experiencing oxygen deprivation (from something like a heart attack or stroke) and keep them alive until they can get to a hospital.

At that time, researchers were trying to identify fetuses at risk for oxygen deprivation, with accompanying brain damage; they developed electronic fetal monitoring in a quest to identify appropriate occasions for intervening during labor.

Furthermore, explained Emilsson, climbers are usually exhausted and a little out of it from oxygen deprivation when they reach the top, so Everest VR will allow them to revisit the experience with a clear head.

A later virtual autopsy was inconclusive about just how Warmbier fell ill, noting that he'd suffered from oxygen deprivation through "an unknown insult more than a year prior to death" that led to brain damage.

When a woman consents to a C-section for fetal distress, she is saying, in essence: I don't know whether my baby is truly experiencing oxygen deprivation, but I don't want to take any chances.

The North Carolina Office of the Chief Medical Examiner said in its report that 59-year-old William Bishop died from oxygen deprivation to the brain due to strangulation and noted ligature marks on his neck.

F-35 fighter jets made by Lockheed Martin were grounded at the Luke Air Force base in Arizona because of irregularities in pilots' oxygen supplies that caused them to suffer symptoms apparently related to oxygen deprivation.

Some research shows that hypoxia, or oxygen deprivation, "entails significant suffering" akin to the pain of a heart attack during which the offender may "begin to drool, urinate, defecate or vomit", remaining conscious all the while.

Other incidents that have hit the F-35 program include a runway fire in Florida in 2014 which led to inspections of the plane's engines; and five incidents in 2017 where pilots reported oxygen deprivation problems.

The 56th on Friday canceled local flying operations for its F-35A Lightning II fighters for the weekend, after five incidents since May 2 in which pilots experienced symptoms similar to hypoxia, also known as oxygen deprivation.

"Carbon monoxide is a known toxicant which causes hypoxia, or oxygen deprivation, which has several well-known and well-studied detrimental effects on pregnancy and offspring development," Bonn-Miller, who wasn't involved the study, said by email.

The Hill's Ellen Mitchell reports: Following a rash of incidents during which pilots appeared to suffer from oxygen deprivation, the Navy will install new oxygen-level monitoring systems on all T-2900 training jets by February. Sen.

They said that a lack of oxygen can lead to hypoxia, or oxygen deprivation, and affect fundamental processes of the brain, like the production of the neurotransmitter serotonin, which is thought to play a key role in mood.

The iconic naked mole-rat, with its ability to resist cancer and oxygen deprivation and seemingly death itself, tends to get much of the research attention, but there are several other species of mole-rats with plenty to offer.

Marine mammals are already difficult to anesthetize, because of concerns that the drug can activate their dive reflex—which helps them conserve oxygen underwater by redirecting blood flow to the heart and lungs—and cause oxygen deprivation or cardiac problems.

MORE (R-Ariz.) is concerned the Air Force has not identified the cause of oxygen deprivation issues with F-35A fighter jets in his home state, despite an investigation and a pause on flights that will be lifted this week.

In the late 1980s, Dr. Semenza, a pediatric geneticist at Johns Hopkins, and Dr. Ratcliffe, a kidney specialist at Oxford, began independently researching how oxygen deprivation, or hypoxia, prompts the production of a hormone that elicits red blood cell production to combat it.

Anything to take your mind away from the fact your body is operating at a height that at which, were the plane to suddenly disappear, the only comfort you'd have would be a few minutes of oxygen deprivation before the ground turned you into human-flavored slurry.

The boy, who was brought in to the hospital on Tuesday night, has been upgraded to good condition, is in "a very delicate situation" and shows no immediate symptoms of long-term injury caused by oxygen deprivation to the brain, police Lt. James Espinoza told the Wichita Eagle.

That's where she got the idea that the same technique might work for a "rapid ascent" on Everest, a peak that people typically spend at least a month getting acclimated to by taking short day hikes from base camp to get their brains and bodies used to high-altitude oxygen deprivation.

Oxygen-deprivation and cockpit-pressurization problems have afflicted trainer and top-line aircraft in the Navy and the Air Force — including the F-22 Raptor, the F-0003A Joint Strike Fighter, the A-10 Thunderbolt, the T-45 Goshawk trainer and F/A-18 Hornet — for at least a decade.

"Naked mole-rats have evolved in an extremely different environment from most other mammals and they have had millions of years to figure out how to survive dramatic oxygen deprivation," said neurobiologist Thomas Park of the University of Illinois at Chicago, who helped lead the study published in the journal Science.

Now, nothing to do with spaetzle or the price of good vanilla, but a good example of how powerful beat reporting is: John Ismay in The Times, on how the military is finally closing in on a solution to oxygen-deprivation and cockpit pressurization problems that have plagued Navy and Air Force aircraft for at least a decade.

He reached higher heights, including 42,000 feet on the fatal November flight on which he died of oxygen deprivation.

These contaminants can cause oxygen deprivation for infants and increase the risk of cancer. Nitrite is significantly more toxic than nitrate. Nitrate, a fertilizer chemical, which can cause oxygen deprivation in infants and increase the risk of cancer. Perchlorate, which is a component of rocket fuel, can interfere with thyroid function if ingested.

Moyamoya disease is an extremely rare cerebrovascular condition that limits blood circulation to the brain, consequently leading to oxygen deprivation.

The road inclination of 4.5% and oxygen deprivation due to altitude make the crossing difficult for both vehicles and people.

Mild symptoms include difficulties with complex learning tasks and reductions in short-term memory. If oxygen deprivation continues, cognitive disturbances, and decreased motor control will result. The skin may also appear bluish (cyanosis) and heart rate increases. Continued oxygen deprivation results in fainting, long-term loss of consciousness, coma, seizures, cessation of brain stem reflexes, and brain death.

Uterine contractions and maternal muscle tone encourage the head to flex. Oxygen deprivation may occur from either cord prolapse or prolonged compression of the cord during birth, as in head entrapment. If oxygen deprivation is prolonged, it may cause permanent neurological damage (for instance, cerebral palsy) or death. It has been suggested that a fast vaginal delivery would mean the risk of stopping baby's oxygen supply is reduced.

The next item of interest is oxygen deficiency, questioning how oxygen deficiency impacts the brain is an important part of comprehending why ASC occurs when there is oxygen deprivation in an environment.

Brain injury as a result of oxygen deprivation either due to hypoxic or anoxic mechanisms are generally termed hypoxic/anoxic injuries (HAI). Hypoxic ischemic encephalopathy (HIE) is a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation is not total. While HIE is associated in most cases with oxygen deprivation in the neonate due to birth asphyxia, it can occur in all age groups, and is often a complication of cardiac arrest.

On July 14, 2016, Matilda Rapaport, a Swedish professional extreme skier, was buried in an avalanche. She died on July 18, 2016 in a hospital in Santiago after suffering oxygen deprivation and brain damage.

Without oxygen, cells cannot manufacture the necessary ATP to regulate ion levels and thus cannot prevent the intracellular environment from approaching the ion concentration of the outside environment. It is not oxygen deprivation itself that precipitates cell death, but rather without oxygen the cell can not make the ATP it needs to regulate ion concentrations and maintain homeostasis. Notably, even a small drop in temperature encourages cell membrane stability during periods of oxygen deprivation. For this reason, a drop in body temperature helps prevent an influx of unwanted ions during an ischemic insult.

Christopher had suffered trauma and oxygen deprivation during the shooting, and died seventeen days later.Englade, p. 73. A private funeral service was held for Christopher on November 20, 1989. Both Carol and Christopher are buried under Carol's maiden name.

Haigh died on 4 February 2018, aged 86. He had spent his last years in a nursing home after oxygen deprivation led to brain damage in 2003, following his accidental swallowing of a bone in a restaurant in Soho.

Cerebral hypoxia is a form of hypoxia (reduced supply of oxygen), specifically involving the brain; when the brain is completely deprived of oxygen, it is called cerebral anoxia. There are four categories of cerebral hypoxia; they are, in order of severity: diffuse cerebral hypoxia (DCH), focal cerebral ischemia, cerebral infarction, and global cerebral ischemia. Prolonged hypoxia induces neuronal cell death via apoptosis, resulting in a hypoxic brain injury. Cases of total oxygen deprivation are termed "anoxia", which can be hypoxic in origin (reduced oxygen availability) or ischemic in origin (oxygen deprivation due to a disruption in blood flow).

Oxygen deprivation that occurs as the result of immobilization (bed rest), glucocorticoid treatment, and withdrawal of oxygen have all been shown to promote osteocyte apoptosis. It is now recognized that osteocytes respond in a variety of ways to the presence of implant biomaterials.

Following an apparent rehabilitation from a severe episode of prolonged cerebral oxygen deprivation, patients with Grinker's myelinopathy begin to experience massive white matter death that leads to a wide range of neurological dysfunctions ranging from confusion and apathy to Parkinson-like symptoms.

A supersonic passenger jet flying over the Pacific Ocean is struck by an errant missile. Due to the effects of decompression and oxygen deprivation, all but a handful are incapacitated. Three survivors must attempt to land the airplane, despite attempts to cover up the disaster.

Intrauterine hypoxia, or oxygen deprivation in the womb, can cause serious brain damage in the fetus. It most commonly occurs because of damage to or malformation of the umbilical cord or placenta. Intrauterine hypoxia can cause brain damage, including cerebral palsy and other neurological and psychiatric disorders.

Most people who travel to high altitudes acclimatize. Acclimatization precludes the development of HACE by maintaining adequate levels of cerebral oxygen. The primary cause of HACE is hypoxia (oxygen deprivation). This occurs after the body is exposed to a low- oxygen environment and before it acclimatizes.

Bunta is an oceanographer who died of oxygen deprivation in a freak submarine accident. He lost his beloved younger sister Nami years earlier in an airplane crash. Bunta's body was cryogenically sustained in a medical facility for research until Joker found him. Using bionic technology, Joker revived Bunta as a cyborg.

In addition to oxygen deprivation or deficiency, infections are a common pathological cause of ASC. A prime example of an infection includes meningitis. The medical website WEBMD states that meningitis is an infection that causes the coverings of the brain to swell. This particular infection occurs in children and young adults.

The consequence of oxygen deprivation in tissues is a switch to anaerobic metabolism at the cellular level. As such, reduced systemic blood flow may result in increased serum lactate. Serum lactate levels have been correlated with illness severity and mortality in critically ill adults and in ventilated neonates with respiratory distress.

She never regained consciousness. Over the following days, doctors performed brain scans that showed she had no brain activity due to oxygen deprivation. On November 4, her parents consented to have her removed from life support. At the request of her mother, Dunne’s kidneys and heart were donated to transplant recipients.

Animals from ‘Brachycephalic’ (pushed faced) breeds, such as bulldogs, pugs and Persian cats, are prone to respiratory problems. Their short nasal passages makes them particularly vulnerable to oxygen deprivation and heat stroke during the process of pet shipping. Most airlines prohibit these breeds from being shipped due to the associated health risks.

This results in an increased mortality rate, including an increased risk of sudden infant death syndrome (SIDS). Oxygen deprivation in the fetus and neonate have been implicated as either a primary or as a contributing risk factor in numerous neurological and neuropsychiatric disorders such as epilepsy, attention deficit hyperactivity disorder, eating disorders and cerebral palsy.

Julia Bailey-Serres is professor of genetics, director of the Center for Plant Cell Biology, and a member of the Institute for Integrative Genome Biology at the University of California, Riverside. Her accomplishments include the pioneering of methods for profiling the "translatomes" of discrete cell-types of plants and identification of a homeostatic sensor of oxygen deprivation in plants.

The US Air Force trains air crews to recognize their individual subjective signs of approaching hypoxia. Some individuals experience headache, dizziness, fatigue, nausea and euphoria, and some become unconscious without warning. Loss of consciousness may be accompanied by convulsions and is followed by cyanosis and cardiac arrest. About 7 minutes of oxygen deprivation causes death of the brainstem.

Onset of symptoms may be after just a few minutes, but usually occurs after at least 20 minutes of free hanging. Typical symptoms are pallor, sweating, shortness of breath, blurred vision, dizziness, nausea, hypotension and numbness of the legs. Eventually it leads to fainting, which may result in death due to oxygen deprivation of the brain.

Microaerophiles can be cultivated in candle jars. Candle jars are containers into which a lit candle is introduced before sealing the container's airtight lid. The candle's flame burns until extinguished by oxygen deprivation, creating a carbon dioxide-rich, oxygen-poor atmosphere. Other methods of creating a microaerobic environment include using a gas-generating pack and gas exchange.

This is obviously only true if the compost is weed free; many are not. For trees and shrubs, mixes of well aged compost with the native soils can be used as backfill. Immature composts may cause settling and young root disturbance due to oxygen deprivation. Seasonally, top dress with compost to the drip line and rake into the soil.

This would result in additional trapped miners and rescue workers. Since miners are trapped in pockets of rock, the risk of an explosion and oxygen deprivation is high. As of 2001, more than 30 million people were employed in the mining industry. Despite that being only 1% of the world's workforce, mining holds over 8% of workplace fatalities.

The effects of a circulatory collapse vary based on the type of collapse it is. Peripheral collapses usually involve abnormally low blood pressure and result in collapsed arteries and/or veins, leading to oxygen deprivation to tissues, organs, and limbs. Acute collapse can result from heart failure causing the primary vessels of the heart to collapse, perhaps combined with cardiac arrest.

Ferrandino, the son of two Italian- American public school teachers, was born in Nyack, New York. He was born with oxygen deprivation and had to have surgery because he was cross eyed. Suffering from multiple learning difficulties, he took special education classes until the fourth grade. He later joined mainstream classes, played the trumpet and captained his high school track team.

Stone and Lloyd, suffering oxygen deprivation, cannot understand the cosmonaut's gestures or obey Keith's orders. Dougherty arrives and he and the cosmonaut transfer the two surviving and mentally dazed Ironman astronauts into the rescue ship. Both the Soviet ship and the X-RV return to Earth, and the final scene fades out with a view of the abandoned Ironman One adrift in orbit.

The ichnogenus is found both in anaerobic, organic-rich sediments and in oxic layers, where it is almost invariably the last in the bioturbation sequence, i.e., it was placed deep within the sediments, away from oxidizing surficial and interstitial water. These suggest the tracemaker's ability to tolerate oxygen deprivation very well. Therefore, Chondrites can be used as an indicator of anoxia in sediments.

Marlise Munoz was 14 weeks pregnant when her husband found her unconscious in November 2013, possibly from a pulmonary embolism. She was subsequently declared brain dead after her arrival at JPS Hospital. Munoz had previously indicated to her husband that she would not like to be kept artificially alive if brain dead. The fetus had suffered from oxygen deprivation and was suspected to be non- viable.

Thus, traveling to remote times poses severe dangers from hypothermia and oxygen deprivation. In the first Pern novel, Dragonflight, Lessa passes out after having travelled back more than four hundred Turns. The Dragonlover's Guide to Pern states that dragons defecate while between. This idea originated with a statement by Anne McCaffrey herself, in answer to a fan's question about the subject at a con.

After the pressure was released, the fresh air caused blinding headaches to the crew, who had suffered oxygen deprivation. Lonsdale clambered to the bridge, and sighting land, decided to try to make for Swedish waters. The confidential papers were consigned to the sea bed, and the Asdics were destroyed and the pieces thrown overboard. Lonsdale sent a message to the Admiralty: "Am making for the Swedish coast".

Tru Confessions is a 2002 Disney Channel Original Movie directed by Paul Hoen and is based on the book of the same name by Janet Tashjian. Tru Walker (Clara Bryant) aspires to be a famous filmmaker. She has a twin brother Eddie (Shia LaBeouf), who is developmentally delayed due to oxygen deprivation at birth. Eddie becomes the subject of Tru's documentary for a film contest she enters.

It is also possible to classify inhalants by the effect they have on the body. Some solvents act as depressants, causing users to feel relaxed or drowsy while others act as stimulants. Many inhalants act primarily as asphyxiant gases, with their primary effect due to oxygen deprivation. Nitrous oxide can be categorized as a dissociative drug, as it can cause visual and auditory hallucinations.

However, if the water is poured uninterruptedly it will lead to death by asphyxia, also called dry drowning. Waterboarding can cause extreme pain, damage to lungs, brain damage from oxygen deprivation, other physical injuries including broken bones due to struggling against restraints, and lasting psychological damage. Adverse physical effects can last for months, and psychological effects for years. The term "water board torture" appeared in press reports as early as 1976.

This secondary injury can cause permanent brain damage. Invasive ICP monitoring allows doctors to determine how much swelling the brain has sustained, and enables cerebrospinal fluid to be drained accordingly in order to prevent oxygen deprivation. In the United States surveys conducted in 1995, 2000 and 2006 have shown that since 1995 (the year the TBI Guidelines were published) ICP Monitoring rose from 32% to 78% in 2005.

Compression of blood vessels may also lead to brain ischemia, by blocking the arteries that carry oxygen to the brain. Tumors are one cause of blood vessel compression. Ventricular tachycardia represents a series of irregular heartbeats that may cause the heart to completely shut down resulting in cessation of oxygen flow. Further, irregular heartbeats may result in formation of blood clots, thus leading to oxygen deprivation to all organs.

Gus makes the decision to leave Hale behind- even choking him, believing he is dead. Ethan has been overcome with oxygen deprivation and needs Gus' assistance to reach safety down the mountain. Unknown to the Morgans, Hale crawls down the mountain through snow, determined to obtain revenge against Gus. In time, though, Hale comes to understand the difficult choice Morgan had to make, and the brothers reconcile their own differences.

Since COHb releases carbon monoxide slowly, less hemoglobin will be available to transport oxygen from the lungs to the rest of the body. Conversion of most Hb to COHb results in death - known medically as carboxyhemoglobinemia or carbon monoxide poisoning. Smaller amounts COHb lead to oxygen deprivation of the body causing tiredness, dizziness, and unconsciousness. COHb has a half-life in the blood of 4 to 6 hours.

Lippincott Williams and Wilkins, 2003. When the uterine muscles contract, they constrict the blood supply to the tissue of the endometrium, which, in turn, breaks down and dies. These uterine contractions continue as they squeeze the old, dead endometrial tissue through the cervix and out of the body through the vagina. These contractions, and the resulting temporary oxygen deprivation to nearby tissues, are responsible for the pain or cramps experienced during menstruation.

Water boils at about and arterial oxygen saturation is about 8% lower than at most visitors' places of residence,Charles Houston, High Altitude: Illness and Wellness. 1993. but it is difficult to distinguish slight oxygen deprivation at the summit from fatigue caused by the exertion required to reach it. Authors speak of possible minimal sensory impairment above . Unlike fitness, age in itself is not a determinant factor in reaching the highest point in the Tatras.

Choking occurs when breathing is impeded by a constricted or obstructed throat or windpipe. In some cases the air flow is completely blocked, in other cases some amount of air can pass to the lungs. Insufficient oxygen being delivered to the body will result in oxygen deprivation. Although oxygen stored in the blood and lungs can keep a person alive for several minutes after breathing stops, this sequence of events can lead to death.

His research has focused on foetal growth restriction, prematurity, parturition, and menopausal medicine. His current research investigates the causes of cerebral palsy, especially dispelling the myth that it is caused by oxygen deprivation or difficulties during birth. He is a founding member of the Friends of Science in Medicine. He was appointed an Officer of the Order of Australia for his services to medicine as a practitioner, a researcher, and a teacher.

Kenneth B. Storey (born October 23, 1949) is a Canadian scientist whose work draws from a variety of fields including biochemistry and molecular biology. He is a Professor of Biology, Biochemistry and Chemistry at Carleton University in Ottawa, Canada. Storey has a world-wide reputation for his research on biochemical adaptation - the molecular mechanisms that allow animals to adapt to and endure severe environmental stresses such as deep cold, oxygen deprivation, and desiccation.

Stress stimuli such as radiation, nutrient deprivation or oxygen deprivation which causes apoptosis will lead to fragmentation of chromatin and cause most cells to apoptose. However a small subset of cells will survive apoptosis. This cleaved DNA will require repair, and when this is done incorrectly, rearrangements will be introduced into the chromosome. There is currently speculation that chromothripsis might be driven by viruses such as γ-herpes viruses which cause cancer, possibly by the inhibition of apoptosis.

Oxygen deprivation in the brain, also known as hypoxia, causes sodium and calcium from outside of the neurons to decrease and intracellular calcium to increase, which harms neuron communication. Lack of oxygen in the brain also causes ATP exhaustion and cellular breakdown from cytoskeleton damage and nitric oxide production. Twenty percent of comatose states result from the side effects of a stroke. During a stroke, blood flow to part of the brain is restricted or blocked.

ATPase inhibitor, mitochondrial is an enzyme that in humans is encoded by the ATPIF1 gene. This gene encodes a mitochondrial ATPase inhibitor. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. It prevents ATPase from switching to ATP hydrolysis during collapse of the electrochemical gradient, for example during oxygen deprivation ATP synthase inhibitor forms a one-to-one complex with the F1 ATPase, possibly by binding at the alpha-beta interface.

A short time after ingestion, the alkaloids produce potentially fatal neuromuscular dysfunction due to failure of the respiratory muscles. Acute toxicity, if not lethal, may resolve in spontaneous recovery, provided further exposure is avoided. The onset of symptoms is similar to that caused by curare, with an ascending muscular paralysis leading to paralysis of the respiratory muscles, causing death from oxygen deprivation. Death can be prevented by artificial ventilation until the effects have worn off 48–72 hours later.

Improbable was her first live foal. He likely suffered oxygen deprivation during the delivery, resulting in a failure to thrive in the days after birth (sometimes called "dummy foal" syndrome). He required intensive medical care and developed a strong attachment to his handlers. Improbable was sold as a weanling in 2016 for $110,000 by Taylor Made Agency, which resold him as a yearling in 2017 for $200,000 to WinStar Farm's Maverick Racing and China Horse Club.

Their research identified that genetic causes, rather than oxygen deprivation or other delivery issues, were the primary cause of cerebral palsy. In May 2018 they announced the results of a large-scale genetic study which identified disruptions in RNA signalling and inflammatory pathways that are common to children with cerebral palsy and autism. He is Head of the Cerebral Palsy Research Group in the university's Paediatrics and Reproductive Health unit. His gynaecological specialty was menopausal medicine.

Failure to relieve the pressure can result in the death of tissues (necrosis) in the affected anatomical compartment, since the ability of blood to enter the smallest vessels in the compartment (capillary perfusion pressure) will fall. This, in turn, leads to progressively increasing oxygen deprivation of the tissues dependent on this blood supply. Without sufficient oxygen, the tissue will die. On a large scale, this can cause Volkmann's contracture in affected limbs, a permanent and irreversible process.

In order to prove his point, the general shoots and kills Gen14's Windsprint. His plans, however, are crossed by Roxy, who levitates the Paladin base into space, knocking them all out due to oxygen deprivation. In the meantime, Caitlin has fully mutated due to the Warhol virus to which she was exposed and is rampaging across town in a Hulk-like fashion. Her rampage is cut short as the Paladin base crash-lands next to her.

A set of professional nail care tools The best way to care for nails is to trim them regularly. Filing is also recommended, as to keep nails from becoming too rough and to remove any small bumps or ridges that may cause the nail to get tangled up in materials such as cloth. Bluish or purple fingernail beds may be a symptom of peripheral cyanosis, which indicates oxygen deprivation. Nails can dry out, just like skin.

If pure nitrous oxide is inhaled without oxygen mixed in, this can eventually lead to oxygen deprivation resulting in loss of blood pressure, fainting and even heart attacks. This can occur if the user inhales large quantities continuously, as with a strap-on mask connected to a gas canister. It can also happen if the user engages in excessive breath-holding or uses any other inhalation system that cuts off a supply of fresh air.Dangers of Nitrous Oxide.

Corneal neovascularization (CNV) is the in-growth of new blood vessels from the pericorneal plexus into avascular corneal tissue as a result of oxygen deprivation. Maintaining avascularity of the corneal stroma is an important aspect of corneal pathophysiology as it is required for corneal transparency and optimal vision. A decrease in corneal transparency causes visual acuity deterioration. Corneal tissue is avascular in nature and the presence of vascularization, which can be deep or superficial, is always pathologically related.

In such individuals, the hemoglobin in red blood cells is extremely sensitive to oxygen deprivation, which results in shorter life expectancy. A person who inherits the sickle cell gene from one parent and a normal hemoglobin allele (HgbA) from the other, has a normal life expectancy. However, these heterozygote individuals, known as carriers of the sickle cell trait, may suffer problems from time to time. The heterozygote is resistant to the malarial parasite which kills a large number of people each year.

Dysfunctions in distinguishing differences in sizes and shapes of objects can have many causes, including brain injury, stroke, epilepsy, and oxygen deprivation. Lesions on the brain that develop as a result of injury or illness impair object recognition. Regions that specifically lead to deficits in object recognition when a lesion is present include the right lateral fusiform gyrus and the ventrolateral occipito-temporal cortex. These areas are crucial to the processing of shape and contour information, which is the basis for object recognition.

With both the white AN-M8 and colored M18 there is a danger of starting a fire if it is used in a dry area. Expended smoke grenade canisters remain hot for some time after burning out and should not be picked up bare-handed. The smoke is harmful if it is inhaled for prolonged periods; new smoke mixtures are under development that are less toxic. In enclosed spaces the smoke displaces oxygen and can cause respiratory or oxygen deprivation.

In the laboratory, epaulette sharks have survived for an hour without any oxygen at 30 °C (86 °F), which is also unusual in that most animals capable of tolerating oxygen deprivation do so at low temperatures. The physiological responses of the epaulette shark to low oxygen are mediated by the nucleoside adenosine. In hypoxic conditions, the heart and ventilation rates drop sharply. The shark's blood pressure falls by half as the blood vessels dilate to deliver more blood to the brain and heart.

Pre-eclampsia, involving oxygen deprivation and death of trophoblastic cells that make up most of the placenta, is a disease which is often associated with maladaptive long-term consequences of inappropriate fetal programming. Here, an inadequately developed and poorly functioning placenta fails to meet the fetus’ nutritional needs during gestation, either by altering its selection for nutrients which can cross into fetal blood or restricting total volume thereof. Consequences of this for the fetus in adult life include cardiovascular and metabolic conditions.

Nancy Laura Spungen was born on February 27, 1958 in Philadelphia, Pennsylvania at the University of Pennsylvania Hospital to Franklin "Frank" (1934-2010) and Deborah Spungen (born 1937). She was born with severe cyanosis and nearly died of oxygen deprivation after being choked by her umbilical cord during delivery. She appeared to have suffered no brain damage and was released from the hospital eight days after birth. The Spungens were a middle-class Jewish family that resided in Lower Moreland Township, a suburb of Philadelphia.

The black-and-white snub-nosed monkey lives at the highest altitude of any known non-human primate. The highest recorded altitude of a group of this species is 4700 m. Surviving in such extreme conditions is only made possible by a mutation in the primate's genomic DNA sequence that allows increased resistance to oxygen deprivation (hypoxia). Other mutations in the DNA sequence have been found to be harmful to the monkeys, as there is evidence of inbreeding and low genetic diversity among populations.

Clements, J. (2010), Schoolgirl Milky Crisis: Adventures in the Anime and Manga Trade, A-Net Digital LLC, pp. 117-118, Satsuma himself suffered numerous medical issues during his tenure, including oxygen deprivation, near-drowning, concussions, electric shocks and lacerations to the legs from the suits' steel wire reinforcements wearing through the rubber padding. The ventilation problem was partially solved in the suit used in 1994's Godzilla vs. SpaceGodzilla, which was the first to include an air duct, which allowed suit actors to last longer during performances.

Marine mammals are able to dive for long periods. Both pinnipeds and cetaceans have large and complex blood vessel systems which serve to store oxygen to support deep diving. Other important reservoirs include muscles, blood, and the spleen which all have the capacity to hold a high concentration of oxygen. They are also capable of bradycardia (reduced heart rate), and vasoconstriction (shunting most of the oxygen to vital organs such as the brain and heart) to allow extended diving times and cope with oxygen deprivation.

These findings were soon to be a foundation for further research into drug development. In the early 1960s, James Black, a Scottish pharmacologist, and associates of his at the Imperial Chemical Industries (ICI) in Great Britain were working on a series of β-adrenergic blocking compounds, pronethalol and propranolol. Dr. Black focused on developing a drug that would relieve the pain of angina pectoris, which results from oxygen deprivation in the heart. His plan was to create a drug that would decrease the heart's requirement for oxygen.

Halon 1211 is typically used in hand-held extinguishers, in which a stream of liquid halon is directed at a smaller fire by a user. The stream evaporates under reduced pressure, producing strong local cooling, as well as a high concentration of halon in the immediate vicinity of the fire. In this mode, fire is extinguished by cooling and oxygen deprivation at the core of the fire, as well as radical quenching over a larger area. After fire suppression, the halon diffuses, leaving no residue.

The final chapter, entitled "Dream", was published as "Episode" 61 of the manga. Notably, the chapter features no elements of the "typical" Franken Fran formula. Instead, most of the chapter consists of Fran being trapped on a sunken ship beneath the ocean, where oxygen deprivation soon leads her to experience a surreal dream - Okita, now a normal human, is her brother, Veronica is no longer a bio-weapon, etc. The dream culminates in an enormous party, which every character to have ever appeared in the manga attends.

One advantage of this method was the availability of larger amounts of nitrogen and flow rates last longer. Nitschke states that nitrogen is also more physiologically inert than helium, with less chance of adverse reaction, and that loss of consciousness is quick with death following within minutes. Unlike helium cylinders, nitrogen cylinders can be refilled in the event of leakage and nitrogen gas can't be detected during an autopsy. ;Process The principle behind the device is oxygen deprivation that leads to hypoxia, asphyxia and death within minutes.

Broden in 2015 Broden argued for continuation of artificial life support for the body of Marlise Munoz and led a vigil outside the Texas hospital where her body was kept on artificial life support. She was 14 weeks pregnant when her husband found her unconscious in November, possibly from a blood clot and subsequently died from brain death. Prior to her death she had indicated that she would not like to be kept artificially alive if brain dead. The fetus had suffered from oxygen deprivation and was suspected to be non-viable.

The term derives from the Latin angere ("to strangle") and pectus ("chest"), and can therefore be translated as "a strangling feeling in the chest". There is a weak relationship between severity of pain and degree of oxygen deprivation in the heart muscle, where there can be severe pain with little or no risk of a myocardial infarction (heart attack) and a heart attack can occur without pain. In some cases, angina can be quite severe. In the early 20th century this was a known sign of impending death.

Euthanasia can be accomplished either through an oral, intravenous, or intramuscular administration of drugs, or by oxygen deprivation (anoxia), as in some euthanasia machines. In individuals who are incapable of swallowing lethal doses of medication, an intravenous route is preferred. The following is a Dutch protocol for parenteral (intravenous) administration to obtain euthanasia: Intravenous administration is the most reliable and rapid way to accomplish euthanasia. A coma is first induced by intravenous administration of 20 mg/kg sodium thiopental (Nesdonal) in a small volume (10 ml physiological saline).

Confirming Finnegan is the fugitive they seek, the Judoon execute her for the murder of an alien princess and return for their ships. Martha uses CPR on the Doctor's two hearts to revive him. The Doctor disables the modified MRI and the Judoon finally shift the hospital back to Earth seconds before everyone perishes from oxygen deprivation. That evening, after a birthday party for Martha's brother Leo ends in a fight, the Doctor invites Martha to go on a trip with him Martha hesitates until the Doctor says he can travel in time as well.

In January 2009, James took part in the Amundsen Omega 3 South Pole Race with his TV presenter friend Ben Fogle and Dr Ed Coats as members of Team QinetiQ, finishing in second, 20 hours behind the winning Norwegian team. The race and the reasons behind was broadcast on BBC Television during summer 2009 in the series On Thin Ice. The trio raised funds for the children's medical research charity Sparks, chosen as the charity partner in memory of Cracknell's niece, Eva, who died at six days old after suffering oxygen deprivation at birth.

The symptoms of brain ischemia reflect the anatomical region undergoing blood and oxygen deprivation. Ischemia within the arteries branching from the internal carotid artery may result in symptoms such as blindness in one eye, weakness in one arm or leg, or weakness in one entire side of the body. Ischemia within the arteries branching from the vertebral arteries in the back of the brain may result in symptoms such as dizziness, vertigo, double vision, or weakness on both sides of the body . Other symptoms include difficulty speaking, slurred speech, and the loss of coordination.

Erick Muñoz petitioned for Marlise to be removed from all life-sustaining measures once brain death had been declared. The hospital refused, citing a Texas law which required that lifesaving measures be maintained if a female patient was pregnant—even if there was written documentation that this was against the wishes of the patient or the next of kin. Erick Muñoz filed suit in state court. In January 2014, Erick Muñoz's attorneys argued that the fetus had suffered from oxygen deprivation and was suspected to be non-viable.

Spontaneous breathing is resumed after the end of the duration of action of curare, which is generally between 30 minutesFor therapeutic dose of tubocurarine by shorter limit as given in: and 8 hours,For 20-fold paralytic dose of toxiferine ("calabash curare"), according to: depending on the variant of the toxin and dosage. Cardiac muscle is not directly affected by curare, but if more than four to six minutes has passed since respiratory cessation the cardiac muscle may stop functioning by oxygen-deprivation, making cardiopulmonary resuscitation including chest compressions necessary.

When a tumor stimulates the growth of new vessels, it is said to have undergone an 'angiogenic switch'. The principal stimulus for this angiogenic switch appears to be oxygen deprivation, although other stimuli such as inflammation, oncogenic mutations and mechanical stress may also play a role. The angiogenic switch leads to tumor expression of pro-angiogenic factors and increased tumor vascularization. Specifically, tumor cells release various pro-angiogenic paracrine factors (including angiogenin, vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and transforming growth factor-β (TGF-β).

In July 2017, it was announced by the UCI that Matija Kvasina had tested positive for an experimental drug known as Molidustat (BAY-85-3934), during two tests taken during the 2017 Fleche du Sud - a race in which he won. Molidustat represents a class of drugs that act on the same physiological pathways and enzyme cascades as those which are activated during altitude training. Oxygen deprivation has the effect of stimulating the body's production of erythropoietin (EPO) - Molidustat imitates this. Kvasina was subsequently kicked out of the 2017 Tour of Austria.

In the special case of infants suffering perinatal asphyxia it appears that apoptosis is a prominent cause of cell death and that hypothermia therapy for neonatal encephalopathy interrupts the apoptotic pathway. In general, cell death is not directly caused by oxygen deprivation, but occurs indirectly as a result of the cascade of subsequent events. Cells need oxygen to create ATP, a molecule used by cells to store energy, and cells need ATP to regulate intracellular ion levels. ATP is used to fuel both the importation of ions necessary for cellular function and the removal of ions that are harmful to cellular function.

By making the cell membrane more impermeable, hypothermia helps prevent the cascade of reactions set off by oxygen deprivation. Even moderate dips in temperature strengthen the cellular membrane, helping to minimize any disruption to the cellular environment. It is by moderating the disruption of homeostasis caused by a blockage of blood flow that many now postulate, results in hypothermia's ability to minimize the trauma resultant from ischemic injuries. Targeted temperature management may also help to reduce reperfusion injury, damage caused by oxidative stress when the blood supply is restored to a tissue after a period of ischemia.

It has a highly unusual set of physical traits that allow it to thrive in a harsh underground environment and is the only mammalian thermoconformer, almost entirely ectothermic (cold- blooded) in how it regulates body temperature. The naked mole-rat lacks pain sensitivity in its skin, and has very low metabolic and respiratory rates. While formerly considered to belong to the same family as other African mole- rats, Bathyergidae, more recent investigation places it in a separate family, Heterocephalidae. The naked mole-rat is also remarkable for its longevity and its resistance to cancer and oxygen deprivation.

He branded the Earth symbol onto one of four Cardinals and murdered him through oxygen deprivation because of the Hassassin lodging dirt into the Cardinal's throat. The Cardinal was murdered at the first altar of science which was Chigi Chapel at the Santa Maria del Popolo. The second Cardinal was branded with the Air symbol and had his lungs punctured and asphysiated. Still alive, the cardinal (in the disguise of a tramp) was escorted to the second altar of science and left to die as Langdon and Vittoria arrived to the altar at the West Ponente of Saint Peter's Square.

In the late 1980s the development of a new set of concepts and problems led to a re- examination. A new generation of neonatal researchers were influenced by the growing evidence that protecting the brain against the effects of oxygen deprivation during labour might be possible. These researchers were aware that cooling produced powerful intra-ischaemic neuroprotection during cardiac surgery but a new concept of hypothermic post-insult neural rescue developed. This shift in thinking was possible because of at least three major new ideas that were developing at the same time: delayed post-ischaemic cell death; excitotoxicity; and apoptosis.

Advances in genomics and functional genomics have enabled large-scale analyses of gene and protein function by means of high-throughput cell biological analyses. Thereby, cells in culture can be perturbed in vitro and the induced effects recorded and analyzed. Perturbations can be triggered in several ways, for instance with molecules (siRNAs, expression constructs, small chemical compounds, ligands for receptors, etc.), through environmental stresses (such as temperature shift, serum starvation, oxygen deprivation, etc.), or combinations thereof. The cellular responses to such perturbations are analyzed in order to identify molecular events in the biological processes addressed and understand biological principles.

Effects of AHT are diffuse axonal injury, oxygen deprivation and swelling of the brain, which can raise pressure inside the skull and damage delicate brain tissue. Traumatic shaking occurs when a child is shaken in such a way that its head is flung backwards and forwards. In 1971, Guthkelch, a neurosurgeon, hypothesized that such shaking can result in a subdural hematoma, in the absence of any detectable external signs of injury to the skull. The article describes two cases in which the parents admitted that for various reasons they had shaken the child before it became ill.

Similar to other rodenticides, the preparation requires 3–7 days to be effective. Rather than killing rodents through internal haemorrhaging as anticoagulants do, PCC affects a rodent’s digestive system, causing acute dehydration due to its extremely absorptive nature (corn cob has been used in applications such as oil spills in water bodies, seed drying and de-icing). Physiological digestive pathways are disrupted, preventing normal regulation of water and salt levels, leading to hypovolemic circulatory shock through reduced blood volume and blood pressure, oxygen deprivation of the blood, and ultimately death. It is by nature biodegradable, thus not an environmental pollutant.

Zeller attempted to hang himself in his University apartment early on Sunday, January 2, 2011. Shortly before, he had posted a 4,000-word suicide note on his website, explaining that he had been sexually abused as a young child, and had decided to take his own life as he felt unable to escape the depression and "darkness" that the memories of this abuse had left him. He was found by officials from Princeton University. As a result of the suicide attempt, he suffered brain damage due to oxygen deprivation, and was in a coma at University Medical Center at Princeton.

A man collapses in a Manhattan street and is taken to a doctor; he has abdominal cramping, retching, confusion and an alarming bluish hue to the skin. The doctor is understandably confused, and at first diagnoses carbon monoxide poisoning, which is known to cause cyanosis (a blue colour to the extremities due to oxygen deprivation). The hospital prepares for a mass poisoning due to a gas leak or other possible cause. They are right to do so, as another ten men turn up at the hospital with the same symptoms — thus the eponymous eleven blue men.

In 2010, a group of environmentalists and geologists discovered that the underground river has a second floor, which means that there are small waterfalls inside the cave. They also found a cave dome measuring above the underground river, rock formations, large bats, a deep water hole in the river, more river channels, and another deep cave, as well as marine creatures and more. Deeper areas of the underground river are almost impossible to explore due to oxygen deprivation. On November 11, 2011, Puerto Princesa Underground River was provisionally chosen as one of the New7Wonders of Nature.

Unbeknownst to the company, the pulse oximeter was also being used to monitor oxygen deprivation in patients under anesthesia in operating rooms. Reports of this application reached the company's management in late 1982, and the company began to focus time and resources in developing operating room applications to help anesthesiologists monitor oxygenation levels in patients on the operating table. The company began to experience competition in the anesthesia market from a new entry into the field, Nellcor. In order to enter the anesthesia market and to mitigate competitive pressures, the company retained Kidder Peabody to assist it in developing a strategic alliance with large corporations in the medical field.

Near the end of September 1982, Jack went to Portsmouth Naval Shipyard in Kittery, Maine for a 27-month overhaul. In April 1983, while in dry dock, she suffered a casualty. While conducting a hydrostatic test of the oxygen banks, the shipyard was using Freon (R-12) as the fluid to conduct the test (the Freon would leave no residue and potential contamination in the O2 banks upon evaporation after the test). One of the shipyard workers was unable to get out of the engineering space in time, and succumbed to the oxygen deprivation effects of the Freon and was not able to be revived.

In the application of internal medicine to psychiatry, his research activities extended to an exploration of the relationship between mental illness and bodily temperature, blood pressure and pulse. In 1881 he published on the relationship between cerebral blood flow and oxygen consumption and posited a connection between cerebral oxygen deprivation, pathological brain circulation and mental illness. While at Bern he also successfully submitted articles on the histological preparation of brain cells, sensory aphasia ("word deafness"), the anatomy of the brain and cerebral localisation and forensic psychiatry. From 1881 until his departure from the Waldau Clinic in 1882, Eugen Bleuler, who coined the term schizophrenia in 1908, served as his medical intern.

Intracellular calcium concentrations are increased further due to the opening of glutamate-regulated ion channels. Ischemia causes anoxic cell depolarizations and it is this increase in membrane potential at the presynaptic cell that triggers the release of glutamate, an excitatory neurotransmitter. Glucose deprivation in the brain for any amount of time has the potential to pose serious consequences, and the amount of time the brain spends under these anoxic conditions is directly related to accumulation of irreversible damage to protein biosynthesis pathways. Protein synthesis all over the body is severely inhibited and essentially comes to a standstill while the brain is suffering from acute oxygen deprivation.

Phosphofructokinase mutation and cancer: In order for cancer cells to meet their energy requirements due to their rapid cell growth and division, they survive more effectively when they have a hyperactive phosphofructokinase 1 enzyme. When cancer cells grow and divide quickly, they initially do not have as much blood supply, and can thus have hypoxia (oxygen deprivation), and this triggers O-GlcNAcylation at serine 529 of PFK. This modification inhibits PFK1 activity and supports cancer proliferation, in contrast with the view that high PFK1 activity is necessary for cancer. This may be due to redirecting glucose flux towards the pentose phosphate pathway to generate NADPH to detoxify reactive oxygen species.

They are rescued by Nick Fury, but Fitz sustains damage to his temporal lobe as a result of oxygen deprivation and is left comatose. In season two, Fitz initially struggles with technology and speech as a result of Ward's actions, but over time becomes a full member of the team again. Near the end of the season, as Fitz arranges for a date with Simmons, a Kree weapon called the "Monolith", which is in S.H.I.E.L.D. custody, breaks free of containment and absorbs Simmons into itself. In season three, Fitz acquires an ancient Hebrew scroll describing the Monolith that consumed Simmons as "Death" (), which Fitz is unable to accept.

Neonatal resuscitation also known as newborn resuscitation is an emergency procedure focused on supporting the approximately 10% of newborn children who do not readily begin breathing, putting them at risk of irreversible organ injury and death. Through positive airway pressure, and in severe cases chest compressions, medical personnel can often stimulate neonates to begin breathing on their own, with attendant normalization of heart rate. About a quarter of all neonatal deaths globally are caused by birth asphyxia.Guidelines on basic newborn resuscitation, 2012, World Health Organization This dangerous condition of oxygen deprivation may begin before birth, for example if the umbilical cord, which supplies oxygen throughout fetal development, is compressed during delivery.

In 1958, Caldeyro-Barcia and Alvarez developed a method to measure the effect of uterine contractions on fetal heart rate, which would later become the basis of fetal monitoring, commonly used to monitor the fetus's response to contractions during labor and to prevent any neurological damage resulting from oxygen deprivation. They defined normal and abnormal responses of the fetus through the continuous monitoring of fetal heart rate. The pair referred to the typical abnormal response of the fetal heart rate during labor as "type II DIP"; the term was later changed to late deceleration by other researchers. Caldeyro-Barcia and his staff developed sub partu tocolysis in 1969.

Because the brain cannot store reserves of oxygen and, unlike other organs, has an exceedingly low tolerance of oxygen deprivation, it is highly vulnerable if vasoconstriction is not reversed. Normally, if the brain is hypoxic, autonomous systems in the body divert blood to the brain at the expense of other organs; because the brain is vasoconstricted this mechanism is not available. Vasoconstriction is only reversed by the build-up of carbon dioxide in the blood through suspension of breathing. In some versions the bear-hug is replaced by pressure on the neck in which case blackout is a hybrid of strangulation and self-induced hypocapnia.

Sleator, William. Interstellar Pig (1984) Insisting that the man is the Devil, the Captain's brother strangles him--and in punishment, is keelhauled. Although he survives, his mind is damaged due to the oxygen deprivation, and he spends the rest of his life locked in his room (which later became Barney's bedroom), scratching patterns into the wooden walls and clinging to the strange trinket he had taken from the murdered man's corpse. That night Barney begins to see a pattern in the marks the Captain's brother had scratched into the window of his bedroom: all the scratches centered on a particular rock on a nearby island.

Potential injuries to the brain include but are not limited to stroke, oxygen deprivation, blunt force trauma, and surgical injuries. When patients have lesions on their brain that develop as a result of injury or illness, such as multiple sclerosis or epilepsy, it is possible that they may have impaired object recognition which can manifest in the form of many different agnosias. Similar deficits have also been observed adults that have suffered blunt force trauma, strokes, severe carbon monoxide poisoning as well as in adults that have surgical damage following removal of tumors. Deficits have also been observed in children with types of epilepsy that do not lead to the formation of lesions.

Survivors of grain entrapment also may require treatment. Many suffer painful contusions from the pressure of the grain they were confined in; it is not uncommon for them to lose consciousness due to the drop in blood pressure as circulation returns to normal. Glenn Blahey, president of the Canadian Agricultural Safety Association (CASA), recalls one incident where a man rescued from a Manitoba grain bin had to be immediately hospitalized as he went into a coma for several days afterwards due to the toxins that had built up in his bloodstream as a result of the oxygen deprivation that occurred during the hours it took to rescue him. Rescued victims have also experienced psychological issues.

Hot, dry periods, when the surface soil dries out to the extent that the lateral roots exude whatever water they contain, will result in the death of such lateral roots unless the water is replaced. Similarly, under extremely wet conditions when lateral roots are inundated by flood waters, oxygen deprivation will also lead to root peril. In plants that exhibit hydraulic redistribution, there are xylem pathways from the taproots to the laterals, such that the absence or abundance of water at the laterals creates a pressure potential analogous to that of transpirational pull. In drought conditions, ground water is drawn up through the taproot to the laterals and exuded into the surface soil, replenishing that which was lost.

The 45-minute documentary is narrated by Irish actor Liam Neeson and was filmed entirely in IMAX. It includes a description of the training required in order to climb the 29,029 feet to the summit of Mount Everest and the challenges faced during the ascent, such as avalanches, blizzards, and oxygen deprivation. The film centers on a team led by Ed Viesturs and Everest director David Breashears; among their number are Spanish climber Araceli Segarra, and Jamling Tenzing Norgay, son of the pioneering Sherpa mountaineer Tenzing Norgay. Everest was in production at the mountain during the 1996 Mount Everest disaster, in which another group of climbers became trapped by a blizzard near the summit.

Called to Mount Vernon, Dr. James Craik, Washington's personal physician, and two other doctors, Dr. Gustavus Richard Brown and Dr. Elisha C. Dick, arrived. Washington's condition rapidly worsened while his doctors purged or bled him and administered various standard medical procedures of the time, all of which had no positive effect to help their dying patient. Dick was strongly against Washington's fourth and final purge because it would seriously weaken Washington, whose skin color had turned blue, a condition of oxygen deprivation. Seeing the gravity of the situation, Dick, the youngest of the three consulting doctors, recommended a tracheotomy to allow air into Washington's lungs and save the patient's life, but the two senior physicians refused to have the fairly-new surgical procedure performed.

There may be an increase in pasture production due to a mulching effect and slight fertilizing effect, such as occurred following the 1980 Mount St. Helens and 1995/96 Mt Ruapehu eruptions. Heavier falls will completely bury pastures and soil leading to death of pasture and sterilization of the soil due to oxygen deprivation. Plant survival is dependent on ash thickness, ash chemistry, compaction of ash, amount of rainfall, duration of burial and the length of plant stalks at the time of ash fall. The acidic nature of ash will lead to elevated soil sulfur levels and lowered soil pH, which can reduce the availability of essential minerals and alter the soil's characteristics so that crops and plants will not survive.

Further action by the ADL also led to Strughold's removal from the International Space Hall of Fame in Alamogordo, New Mexico in May 2006. Further questions about Strughold's activities during World War II emerged in 2004 following an investigation conducted by the Historical Committee of the German Society of Air and Space Medicine. The inquiry uncovered evidence of oxygen deprivation experiments carried out by Strughold's Institute for Aviation Medicine in 1943. According to these findings six epileptic children, between the ages of 11 and 13, were taken from the Nazi's Brandenburg Euthanasia Centre to Strughold's Berlin laboratory where they were placed in vacuum chambers to induce epileptic seizures in an effort to simulate the effects of high-altitude sicknesses, such as hypoxia.

Canzano has won numerous accolades in her career, including the 2012 Best Investigative Reporting Award from the Oregon Association of Broadcasters. She also received the Edward R. Murrow Award in Investigative Reporting in 2007 for her piece on Jordaan Clarke, who after undergoing successful heart surgery at Oregon Health and Science University (OHSU) hospital as an infant, suffered prolonged oxygen deprivation causing permanent and profound brain damage. Canzano's report revealed that OHSU benefits from rare and unusual protection from the state that caps malpractice damages at $200,000 per incident, a luxury not widely available to other entities in the state of Oregon, according to documents obtained by the reporter."Report: OHSU benefits from tort cap" (September 1, 2008). The Oregonian, Staff Reports, p. A2.

Dr. Malocchio is believed to be deceased but is actually living in a secret base with Mr. Awesome, who is attempting to find the cure for the evil super-gene formula. In the season two finale, thanks to the blood transfusion from Mr. Awesome he finally becomes good again but a mishap in the lab resulted in his evil-genes entering into Mr. Awesome's bloodstream making him evil as a result. He agreed to return to Earth to warn the Awesomes about what happened, but was locked out of the escape capsule when he stepped outside to urinate and it drifted away. Suffering from oxygen deprivation and severely amnesiac, Malocchio was rescued by a troupe of space hippies in a psychedelically-painted craft.

He is nearly drowned after using the explosive, while Simmons swims to the surface with his unconscious body, where they are rescued by Nick Fury, who picked up their distress signal. Fitz survives, but sustains damage to his temporal lobe as a result of oxygen deprivation and is left comatose. After being saved from death by Raina's synthesized GH325, Garrett begins exhibiting the super-strength given by the Centipede serum, as well as the manic behavior and hypergraphia caused by GH325, and the symbols he carves resemble those found by Ward in the Todorov Building in Minsk. Coulson, May, Skye and Triplett use the Trojan to locate the new Cybertek facility, and launch an assault while Quinn is giving some military generals a tour.

The team finished a fantastic third and gained England another medal and contributing to their total of 80 medals at these Games. In 1967, Warden competed at the Kenya AAA's Championships (known as the 'Three As') and finished third despite the oxygen deprivation caused by competing at 1,795m above sea-level. In the report by British Pathé, Warden and the British athletes had to be given pure oxygen after their races due to the impact of the altitude on their bodies. He is currently listed as 66th on the British All-Time list for the 400 meter hurdles Under the British Athletics Federation (later became UK Athletics) Warden was made National Coach for the North West and was later made National Jumps Coach.

His research projects, funded by grants from the NHMRC, the Cerebral Palsy Foundation, and The Tenix Foundation (2010–2017), investigated foetal growth restriction, prematurity, parturition, and cerebral palsyespecially disproving the previously widespread belief that it is caused by oxygen deprivation due to delivery problems. In 2013, the Cerebral Palsy Alliance's Research Foundation provided his team with a grant of AU$800,000 to help establish an Australian Cerebral Palsy Biobank. He leads the Australian Collaborative Cerebral Palsy Research Group, investigating the roles that genetic susceptibility and environmental triggers have in cerebral palsy. After retiring from his full-time academic position, he remains on the emeritus staff of the Robinson Institute, where his research team challenged the myth that cerebral palsy is usually due to lack of oxygen at birth.

According to Sarno, TMS is a condition in which unconscious emotional issues (primarily rage) initiate a process that causes physical pain and other symptoms. His theory suggests that the unconscious mind uses the autonomic nervous system to decrease blood flow to muscles, nerves or tendons, resulting in oxygen deprivation (temporary micro-ischemia) and metabolite accumulation, experienced as pain in the affected tissues. Sarno theorizes that because patients often report that back pain seems to move around, up and down the spine, or from side to side, that this implies the pain may not be caused by a physical deformity or injury. Sarno states that the underlying cause of the pain is the mind's defense mechanism against unconscious mental stress and emotions such as anger, anxiety and narcissistic rage.

All sprints beyond this distance increasingly incorporate an element of endurance.200 m For the Expert. IAAF. Retrieved on 26 March 2010. Human physiology dictates that a runner's near-top speed cannot be maintained for more than thirty seconds or so because lactic acid builds up once leg muscles begin to suffer oxygen deprivation. Top speed can only be maintained for up to 20 metres.Usain Bolt 100m 10 meter - Splits and Speed Endurance Retrieved 6 February 2013 The 60 metres is a common indoor event and indoor world championship event. Less-common events include the 50 metres, 55 metres, 300 metres and 500 metres which are run in some high school and collegiate competitions in the United States. The 150 metres, though rarely competed, has a star-studded history: Pietro Mennea set a world best in 1983,Superb Bolt storms to 150m record .

Tenacious lawyer Lieutenant Colonel Sarah "Mac" MacKenzie (Catherine Bell), a by-the-book Marine, is tasked with prosecuting, defending, and enforcing the laws of the sea as a member of the Navy's elite Judge Advocate General Corps. Along with her partner Commander Harmon "Harm" Rabb, Jr. (David James Elliott) - a former Tomcat pilot - Mac investigates a plethora of cases including desertion ("The Promised Land"), oxygen deprivation ("In Thin Air"), sexual harassment ("Offensive Action"), a mishap aboard the USS Seahawk ("When the Bough Breaks"), and a death during surgery ("Complications"). Also this season, Bud Roberts (Patrick Labyorteaux) is injured in Afghanistan ("Critical Condition"), Petty Officer Jennifer Coates (Zoe McLellan) joins JAG ("All Ye Faithful"), Commander Theodore Lindsey (W.K. Stratton) returns ("Fortunate Son"), Clayton Webb (Steven Culp) goes missing in Paraguay ("A Tangled Webb"), and Rear Admiral A.J. Chegwidden (John M. Jackson) accidentally ejects from an F-14 Tomcat ("Heart and Soul").

Tooth decay There are certain diseases and disorders affecting teeth that may leave an individual at a greater risk for cavities. Molar incisor hypomineralization, which seems to be increasingly common. While the cause is unknown it is thought to be a combination of genetic and environmental factors. Possible contributing factors that have been investigated include systemic factors such as high levels of dioxins or polychlorinated biphenyl (PCB) in the mother's milk, premature birth and oxygen deprivation at birth, and certain disorders during the child's first 3 years such as such as mumps, diphtheria, scarlet fever, measles, hypoparathyroidism, malnutrition, malabsorption, hypovitaminosis D, chronic respiratory diseases, or undiagnosed and untreated coeliac disease, which usually presents with mild or absent gastrointestinal symptoms. Amelogenesis imperfecta, which occurs in between 1 in 718 and 1 in 14,000 individuals, is a disease in which the enamel does not fully form or forms in insufficient amounts and can fall off a tooth.

Other researchers have developed an autism severity score to measure the degree of severity of the mice's autism, as well as the use of scent marking behavior and vocalization distress as models for communication. It has been observed that mice lacking the gene for oxytocin exhibit deficits in social interaction, and that it may be possible to develop treatments for autism based on abnormalities in this and other neuropeptides. Environmental Factors of ASD Looking at the environmental factors of autistic spectrum disorder in rodents helps us to understand the neuropathology of the disorder which can be compared to humans. Environmental factors have been studied in animal rodent models and have been seen to influence brain development and play a role in CNS neuropathology. For example, one study found that a possible environmental contributor to autism may be agents like prenatal exposure to air pollution or any birth difficulty leading to periods of oxygen deprivation to the brain, which alter serotonin levels in early development of the rodent1.

The fetus had suffered from oxygen deprivation and was suspected to be non-viable; the fetus's lower extremities were deformed to the extent that the gender couldn't be determined, had fluid building up inside the skull (hydrocephalus); and possibly had a heart problem. An attorney who had helped rewrite the Texas state law being used to keep her body on life support at John Peter Smith Hospital said that there was a problem with the application of the law to a patient that was no longer alive. Her husband Eric, with the support of her family, successfully sued the hospital for withdrawing treatment. Numerous states have adopted laws restricting the ability of doctors to end artificial life support for terminally ill pregnant patients with 12 of those states (including Texas) with the most restrictive such laws, which automatically invalidate a woman’s advance directive if she is pregnant stating that, regardless of the progression of the pregnancy, a woman must remain on life sustaining treatment until she gives birth with no exception for patients who will be in prolonged severe pain or who will be physically harmed by continuing life sustaining treatment.

Wall, Robert and Amy Butler. "USAF Weighs Future Priority Needs." Aviation Week, 21 November 2011. To address oxygen deprivation issues, F-22s were fitted with an automatic backup oxygen system (ABOS) and modified life support system starting in 2012. Increment 3.2 for Block 35/40 aircraft is a two-part upgrade process; 3.2A focuses on electronic warfare, communications and identification, while 3.2B includes geolocation improvements and a new stores management system to fully integrate the AIM-9X and AIM-120D."A transitional year for military combat aircraft", Aviation Week and Space Technology, December 1/8, 2014, p. 60. To enable two-way communication with other platforms, the F-22 can use the Battlefield Airborne Communications Node (BACN) as a gateway. The planned Multifunction Advanced Data Link (MADL) integration was cut due to development delays and lack of proliferation among USAF platforms. The F-22 fleet began receiving Increment 3.2B and upgraded software for cryptography capabilities and avionics stability in May 2019. A Multifunctional Information Distribution System-Joint (MIDS-J) radio that replaces the current Link-16 receive-only box is expected to be operational by 2020.