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136 Sentences With "opacities"

How to use opacities in a sentence? Find typical usage patterns (collocations)/phrases/context for "opacities" and check conjugation/comparative form for "opacities". Mastering all the usages of "opacities" from sentence examples published by news publications.

Their device embeds a tiny monochrome LCD in the lens that can be set to varying opacities and patterns.
Narrator: While bright-white veneers may have four to five shades, Apa&aposs teeth use 17 to 20 different shades and opacities.
Another definite evidence of the virus are ground-glass opacities (white multifocal circles) in the lungs, which are seen in CT scan results.
Out of a commendable distaste for the opacities of artspeak, Perl insists on a simplicity of language that can sometimes spill over into the fatuous.
This is not exactly a bad deal for Tebow, who is being paid $100,000 based off one janky workout and various opacities about character and potential.
"At present it's far from clear how regions with the same amount of material can have such different opacities," Matthew Hedman, another co-author of the study said.
Whereas the U.S. market is relatively transparent and efficient, markets in developing countries have opacities and inefficiencies that could allow a well-researched active manager to gain an upper hand.
They therefore started experimenting with cheap, non-toxic UV-filtering films of various opacities, and found that the strongest of these could delay the sensor's colour change by 9½ hours—nearly twice what was needed.
That study and work by Dr. Xiao show that as the disease progresses, CT scans show "ground glass opacities," a kind of hazy veil in parts of the lung that are evident in many types of viral respiratory infections.
Beyond the legal loopholes the case elucidates, the system that dispossessed Young's heirs is a cautionary tale about the art world's many opacities and ambiguities, and how they send shock waves through the lives of people outside of it.
These "treatment" foundations now heal skin with an even lighter, more breathable feel — thanks to new "finishes, opacities and textures," according to the Toronto-based cosmetic chemist Stephen Alain Ko. The resulting dewy glow lasts — even after washing off your makeup.
While the two bodies or work remain distinct, they operate elegantly together to address the opacities of communication and the illegibility of suffering, whether imposed by social, political, and juridical conditions or inherent to the nature of pain and memory.
The DTR's artists clearly illustrated with a scientific mind, as they showed specimens from various perspectives to fully capture their form or indicate how they move; some illustrations feature multiple iterations of a single specimen but rendered with different opacities, colors, or textures.
Javier Garcia at Caltech told Gizmodo in an email: "It is truly remarkable that in a laboratory on Earth into plasma opacities, the Sandia Z group are connecting and shedding light on plasma processes in both the Sun and in accretion disks around black holes."[PRL]
Older patients may show faint to definite central, horizontally oval, bilateral stromal opacities. The opacities may be associated with decreased visual acuity, but they have not been severe enough to need corneal transplantation.
Excimer laser phototherapeutic keratectomy (PTK) is useful in superficial (nebular) corneal opacities.
In those who have lung involvement, a chest X-ray may demonstrate diffuse alveolar opacities.
Fleck corneal dystrophy, also known as Francois-Neetens speckled corneal dystrophy, is a rare form of corneal dystrophy. It is caused by mutations in PIKFYVE gene. Small opacities, some of which resemble "flecks", are scattered in the stroma of the patients. Other opacities look more like snowflakes or clouds.
Corneal opacities, the hallmark of the chronic phase, are usually self-limited. They may occur as numular keratitis.
The eyes may develop a white or clear covering the cornea (corneal opacities) which can cause problems with vision.
Rarely other manifestations can be seen on CT scans, including military nodular opacities, perihilar opacities (that mimic hilar lymphadenopathy), pleural effusions and pulmonary masses. Cavitation and aspergilloma are rarer findings, not exceeding 20% of patients, and likely represent a shift from ABPA to CPA if accompanied by pleural thickening or fibrocavitary disease.
The leading reason for corneal tattooing is to alter the appearance of the eye cosmetically. Usually, the need for this alteration stems from corneal opacity. Corneal opacities (scarring of the cornea that creates an opaque or semi-transparent area on the eye) may be caused by leucoma, keratitis or cataracts. Such opacities can be cosmetically disruptive for patients in their everyday lives.
Phototherapeutic keratectomy (PTK) can be used to excise or ablate the abnormal corneal tissue. Patients with superficial corneal opacities are suitable candidates for this procedure.
Small nodular opacities occur in up to 50% of patients and large nodules in 15%. On high resolution computed tomography, airspace consolidation with air bronchograms is present in more than 90% of patients, often with a lower zone predominance. A subpleural or peribronchiolar distribution is noted in up to 50% of patients. Ground glass appearance or hazy opacities associated with the consolidation are detected in most patients.
CT scanning and radiography can be used to aid in the diagnosis of indium lung. CT abnormalities include ground-glass opacities, interlobular septal thickening, honeycombing, and bronchiectasis.
Clin Experiment Ophthalmol. 2009 Jan;37(1):81-9.Khurana et al. High- speed optical coherence tomography of corneal opacities. Ophthalmology. 2007 Jul;114(7):1278-85.
The prevalence of congenital corneal opacities (CCO) is estimated to be 3 in 100,000 newborns. This number increases to 6 in 100,000 if congenital glaucoma patients are included. A study of live births in Spain reported that corneal opacities accounted for 3.11% of congenital eye malformations (Bermejo et al, 1998). About 4% of keratoplasties done in the pediatric population in Denmark are due to congenital anomalies (Hovlykke et al, 2014).
Asteroid hyalosis is a degenerative condition of the eye involving small white opacities in the vitreous humor. It is known to occur in humans, dogs, cats, horses, and chinchillas. Clinically, these opacities are quite refractile, giving the appearance of stars (or asteroids) shining in the night sky—except that ocular asteroids are often quite mobile. Ocular asteroids must be distinguished from the more common typical vitreous floaters, which are usually fibrillar or cellular condensates.
Optical iridectomy creates a clear entrance pupil, improving vision in patients with segmental corneal opacities. An area of clear peripheral cornea can produce retinal images compatible with good visual acuity.
With time, the corneal changes progress into opacities in Bowman's membrane, which gradually becomes more irregular and more dense. Significant vision loss may occur. However, vascularization of the cornea is not present.
Much more commonly, misuse of contact lenses may be a precipitating factor. Whichever, it is always potentially serious and sometimes necessitates urgent treatment and corneal opacities are the fourth leading cause of blindness. Opacities may be keratic, that is, due to the deposition of inflammatory cells, hazy, usually from corneal edema, or they may be localized in the case of corneal ulcer or keratitis. Corneal epithelial disruptions may be detected with fluorescein staining of the eye, and careful observation with cobalt-blue light.
Post-eruptive breakdown (PEB) is a clinical feature, often observed in the majority of severely affected cases. The rate of PEB may be increased by the loading of masticatory forces on enamel weakened by MIH. The lesions resulting from PEB are irregularly shaped, with rough margins from the shearing of the enamel. PEB is more likely to occur in MIH affected teeth with yellow or brown opacities rather than those with white opacities, as darker lesions reflect a greater deficit in mineral content.
Diagnosis can be established on clinical grounds and this may be enhanced with studies on surgically excised corneal tissue and in some cases with molecular genetic analyses. As clinical manifestations widely vary with the different entities, corneal dystrophies should be suspected when corneal transparency is lost or corneal opacities occur spontaneously, particularly in both corneas, and especially in the presence of a positive family history or in the offspring of consanguineous parents. Superficial corneal dystrophies - Meesmann dystrophy is characterized by distinct tiny bubble-like, punctate opacities that form in the central corneal epithelium and to a lesser extent in the peripheral cornea of both eyes during infancy that persists throughout life. Symmetrical reticular opacities form in the superficial central cornea of both eyes at about 4–5 years of age in Reis-Bücklers corneal dystrophy.
The SLA standard resins come in different colours and opacities. Besides the engineering grade materials like the ABS-like or PP-like resin, there exist bio-compatible ones used for medical applications and flexible resins.
Topical cyclosporin A (CsA) appears to be effective in the treatment of persistent corneal opacities. Topical interferon might be effective as a prophylaxis of infection. Topical interferon is currently not commercially available due to unsettled patent issues.
Diffuse opacities of enamel does not affect the amount of enamel but changes its appearance. Affected enamel has a different translucency than the rest of the tooth. Demarcated opacities of enamel have sharp boundaries where the translucency decreases and manifest a white, cream, yellow, or brown color. All these may be caused by nutritional factors, an exanthematous disease (chicken pox, congenital syphilis), undiagnosed and untreated celiac disease,Dental Enamel Defects and Celiac Disease National Institute of Health (NIH) hypocalcemia, dental fluorosis, birth injury, preterm birth, infection or trauma from a deciduous tooth.
Topical steroids should be avoided because they prolong viral replication, frequently lead to long-lasting dry eye symptoms, and corneal opacities almost always recur after discontinuation of topical steroids. There is currently no effective and clinically applicable topical antiviral agent for the treatment of the acute phase of AKC. Topical cidofovir is the first antiviral agent which has effectively reduced the incidence of corneal opacities, but local toxicity rules out its clinical application. Recently, NMSO3, a sulfated sialyl lipid, has demonstrated a greater antiviral potency against adenovirus in vitro than cidofovir exhibiting minimal cytotoxicity.
It corresponds to an opacity of 20%. Shades 2, 3, 4 and 5 correspond to opacities of 40%, 60%, 80% and 100% (completely black) and are usually considered to be "black smoke" by air pollution boards of most countries.
They initially appear within the first decade of life. Visual acuity is more or less normal. Lattice dystrophy starts as fine branching linear opacities in Bowman's layer in the central area and spreads to the periphery. Recurrent corneal erosions may occur.
Kerley lines are a sign seen on chest radiographs with interstitial pulmonary edema. They are thin linear pulmonary opacities caused by fluid or cellular infiltration into the interstitium of the lungs. They are named after Irish neurologist and radiologist Peter Kerley.
Radiographically, CWP can appear strikingly similar to silicosis. In simple CWP, small rounded nodules (see ILO Classification) predominate, tending to first appear in the upper lung zones. The nodules may coalesce and form large opacities (>1 cm), characterizing complicated CWP, or PMF.
Clubbing is observed in 50% of patients. Tachypnea, respiratory distress, and inspiratory crackles over lower lung fields often are present. On chest radiographs, progressive fibrotic changes with loss of lung volume particularly affect the upper lobes. Nodular or ground-glass opacities are not present.
When they are very numerous, superimposition may give the impression of confluency, but this does not seem to occur in reality. The hilar lymph nodes can be very opaque but not enlarged. After cessation of exposure, there is a gradual clearing of the opacities.
Imaging abnormalities are typically bilateral and are usually described as "pulmonary infiltrates or opacities" on chest X-ray and "ground-glass opacities" on chest CT. Bronchoalveolar lavage specimens may exhibit an increased level of neutrophils in combination with lymphocytes and vacuole-laden macrophages. Lavage cytology with oil red O staining demonstrated extensive lipid-laden alveolar macrophages. In the few cases in which lung biopsies were performed, the results were consistent with acute lung injury and included a broad range of features, such as acute fibrinous pneumonitis, diffuse alveolar damage, lipid-laden macrophages, and organizing pneumonia. Lung biopsies often showed neutrophil predominance as well, with rare eosinophils.
The pattern deviation provides a numerical total and statistical display as the Total Deviation plot. However, it accounts for general reductions of vision caused by media opacities (e.g. cataract), uncorrected refractive error, reductions in sensitivity due to age and pupil miosis. This highlights focal loss only (i.e.
The lesions that appear in teeth affected with MIH can present as opacities that vary from white to yellow- brown. They are usually asymmetrical in appearance, with a sharp demarcation that distinguishes between normal and affected enamel. The lesions usually do not involve the cervical third of affected teeth.
Opacities due to MIH can be quite visible especially on anterior teeth which could present as a problem aesthetically. Patients frequently claim aesthetic discomfort when anterior teeth are involved. The discoloured appearance of the anterior teeth could also have negative effects on a child’s psychological development and self-esteem.
The chest radiograph may appear relatively normal, even late in the disease, or may suggest hyperinflation only. As the disease progresses, the chest radiograph often demonstrates diffuse, bilateral and symmetric reticulonodular opacities, cysts, bullae or a "honeycomb" (i.e., pseudo fibrotic) appearance. Pleural effusion and pneumothorax may be apparent.
In his first year at Cambridge, as a research student of Fowler, Chandrasekhar spent his time calculating mean opacities and applying his results to the construction of an improved model for the limiting mass of the degenerate star. At the meetings of the Royal Astronomical Society, he met E. A. Milne. At the invitation of Max Born he spent the summer of 1931, his second year of post-graduate studies, at Born's institute at Göttingen, working on opacities, atomic absorption coefficients, and model stellar photospheres. On the advice of P. A. M. Dirac, he spent his final year of graduate studies at the Institute for Theoretical Physics in Copenhagen, where he met Niels Bohr.
Currently, there is no specific treatment to correct the LCAT deficiency so therapy is focused on symptom relief. Corneal transplant may be considered for patients presenting with severely impaired vision caused by cholesterol corneal opacities. Dialysis may be required for patients presenting with kidney failure, and kidney transplant may be considered.
The six track EP, titled Opacities, was released on 4 December 2015. Sikth were also the opening act for Slipknot on their 2016 U.K tour in February alongside Suicidal Tendencies. They were announced to be performing the Arctangent Festival in August 2016, but later pulled out. They appeared in 2017.
Causes or reasons for corneal tattooing vary from patient to patient. Most patients receive treatment to alter the cosmetic appearance of their eyes following disease or accident. Others receive treatment for optical purposes, including decreasing circumstantial glare within the iris. Corneal opacities are the leading reason for undergoing cosmetic tattooing.
This cloudiness, or opacity, causes the corneal epithelium to become elevated, which leads to corneal opacities. The corneal erosions may prompt attacks of redness and swelling in the eye (ocular hyperemia), eye pain, and photophobia. Significant vision loss may occur. Reis-Bücklers dystrophy is diagnosed by clinical history physical examination of the eye.
It was found to not affect the corneal stromal layer or endothelial cell layer. Signs of this disease appear in the early first few years of life and begin as eye irritation. Under magnification, corneal changes consisting of punctate opacities in the epithelium are found. Occasionally, these are found in the Bowman membrane.
It generally does not cause any symptoms. The strands can connect to the cornea or lens, but most commonly to other parts of the iris. Attachment to the cornea can cause small corneal opacities, while attachment to the lens can cause small cataracts. Using topical atropine to dilate the pupil may help break down PPMs.
Respiratory samples from a man hospitalized in Paris, France were retrospectively diagnosed as having SARS-CoV-2 virus present. The man presented with advanced symptoms (chest CT of ground glass opacities). His child had previously presented with influenza-like illness. The man had not traveled recently (his last travel outside of France had been to Algeria in Aug 2019).
Florida keratopathy appears as multiple cloudy opacities in the stromal layer of the cornea. The spots appear concentrated at the center and become more diffuse at the periphery. They can range in size from one to eight millimeters. There are no other symptoms, and there is no response to treatment with either anti-inflammatory or antimicrobial drugs.
Typical visible features on CT initially include bilateral multilobar ground-glass opacities with a peripheral or posterior distribution. COVID-19 can be identified with higher precision using CT than with RT-PCR. Subpleural dominance, crazy paving, and consolidation may develop as the disease evolves. Chest CT scans and chest x-rays are not recommended for diagnosing COVID-19.
There are long hyperdense opacities that resemble fetal bones. Foetus in foetu (or fetus in fetu) is a developmental abnormality in which a mass of tissue resembling a foetus forms inside the body. An early example of the phenomenon was described in 1808 by George William Young. There are two theories of origin concerning "foetus in foetu".
The Future in Whose Eyes? is the third studio album by British progressive metal band Sikth, their first full-length album since their 2008–2013 hiatus, following their return EP Opacities (EP). It was released worldwide on 2 June 2017. It is the first album to feature new vocalist Joe Rosser, who replaced vocalist Justin Hill in 2016.
Some medications, such as systemic, topical, or inhaled corticosteroids, may increase the risk of cataract development. Corticosteroids most commonly cause posterior subcapsular cataracts. People with schizophrenia often have risk factors for lens opacities (such as diabetes, hypertension, and poor nutrition) but antipsychotic medications are unlikely to contribute to cataract formation. Miotics and triparanol may increase the risk.
In a number of breast pathologies, calcium is often deposited at sites of cell death or in association secretions or hyalinized stroma, resulting in pathologic calcification. For example, small, irregular, linear calcifications may be seen, via mammography, in a ductal carcinoma-in-situ to produce visible radio- opacities. Robbins and Cotran (2009), Pathologic Basis of Disease, 8th edition, Elsevier.
Baritosis is a benign type of pneumoconiosis, which is caused by long-term exposure to barium dust. Barium has a high radio-opacity and the disease may develop after few months of exposure. Extremely dense, discrete small opacities of 2–4 mm diameter, sometimes of a star-like configuration, are seen on the radiograph. Their distribution is uniform.
Congenital cataract, which may be detected in adulthood, has a different classification and includes lamellar, polar, and sutural cataracts. Cataracts can be classified by using the lens opacities classification system LOCS III. In this system, cataracts are classified based on type as nuclear, cortical, or posterior. The cataracts are further classified based on severity on a scale from 1 to 5.
Patients with subacute HP gradually develop a productive cough, dyspnea, fatigue, anorexia, weight loss, and pleurisy. Symptoms are similar to the acute form of the disease, but are less severe and last longer. On chest radiographs, micronodular or reticular opacities are most prominent in mid-to- lower lung zones. Findings may be present in patients who have experienced repeated acute attacks.
Chest X-rays taken shortly after the accident may or may not be abnormal, but typically over time show infiltrates in the lower lobes of the lungs. High-resolution CT will frequently demonstrate abnormalities, including opacities, pleural effusion, consolidation, or pulmonary nodules. Histopathology of lung biopsy or bronchoalveolar lavage may indicate lipid-laden macrophages. Laboratory results may show highly elevated inflammatory markers.
The Boston KPro is a treatment option for corneal disorders not amenable to standard penetrating keratoplasty (corneal transplantation) or corneal transplant. The Boston KPro is a proven primary treatment option for repeat graft failure, herpetic keratitis, aniridia and many pediatric congenital corneal opacities including Peter's anomaly. The device is also used to treat cicatrizing conditions including Stevens–Johnson syndrome and ocular cicatricial pemphigoid, and also ocular burns.
Filamentous opacities appear in the cornea with intertwining delicate branching processes. During an eye examination, the doctor sees these deposits in the stroma as clear, comma- shaped overlapping dots and branching filaments, creating a lattice effect. Over time, the lattice lines will grow opaque and involve more of the stroma. They will also gradually converge, giving the cornea a cloudiness that may also reduce vision.
Symptoms of the familial form include visual impairment caused by diffuse corneal opacities, target cell hemolytic anemia, and kidney failure. Less common symptoms include atherosclerosis, hepatomegaly (enlarged liver), splenomegaly (enlarged spleen), and enlarged lymph nodes. Fish-eye disease is less severe and most commonly presents with impaired vision due to corneal opacification. It rarely presents with other findings, although, atherosclerosis, hepatomegaly, splenomegaly, and lymphadenopathy can occur.
Onset occurs in the first decade, usually between ages 5 and 9. The disorder is progressive, vision changes with ageing from 2nd decade to 3rd visual impairment may seen in 4th and 5th decade severe visual impairment can be seen Minute, gray, punctate opacities develop. Corneal sensitivity is usually reduced. Painful attacks with photophobia, foreign body sensations, and recurrent erosions occur in most patients.
Todd Sanders and Harry West for example suggest not only that realms of the revealed and concealed require each other, but also that transparency in practice produces the very opacities it claims to obviate.Sanders, Todd & Harry G. West 2003. Powers revealed and concealed in the New World Order. In H. G. West & T. Sanders (eds) Transparency and Conspiracy: Ethnographies of Suspicion in the New World Order.
Congenital cataracts refers to a lens opacity which is present at birth. Congenital cataracts cover a broad spectrum of severity: whereas some lens opacities do not progress and are visually insignificant, others can produce profound visual impairment. Congenital cataracts may be unilateral or bilateral. They can be classified by morphology, presumed or defined genetic cause, presence of specific metabolic disorders, or associated ocular anomalies or systemic findings.
Macular corneal dystrophy, also known as Fehr corneal dystrophy named for German ophthalmologist Oskar Fehr (1871-1959), is a rare pathological condition affecting the stroma of cornea. The first signs are usually noticed in the first decade of life, and progress afterwards, with opacities developing in the cornea and attacks of pain. The condition was first described by Arthur Groenouw in 1890.Groenouw A. Knötchenförmige Hornhauttrübungen (noduli corneae).
Chronic cough and exertional dyspnea (shortness of breath) are common findings. Radiographically, chronic simple silicosis reveals a profusion of small (<10 mm in diameter) opacities, typically rounded, and predominating in the upper lung zones. ;Accelerated silicosis: Silicosis that develops 5–10 years after first exposure to higher concentrations of silica dust. Symptoms and x-ray findings are similar to chronic simple silicosis, but occur earlier and tend to progress more rapidly.
The most common findings on HRCT are diffuse hyperdense ground- glass attenuation and subpleural linear calcifications, often most predominant in the inferior and posterior portions of the lungs. Additionally, the medial aspects of the lungs appear to be more heavily involved than the lateral aspects. Ground-glass opacities, probably due to small calculi in the air space, are the most common finding in children and in patients with early- stage PAM.
Acute phase with conjunctival inflammation Adenoviral keratoconjunctivitis, also known as Keratoconjunctivitis epidemica is a common and highly contagious viral infection of the eye. The clinical course of (AKC) should be divided into an acute phase with conjunctival inflammation of varying intensity with or without corneal involvement and a chronic phase with corneal opacities. AKC is caused by many different serotypes and is highly contagious during the acute phase.
Phialemonium curvatum has been found to be capable of causing endophthalmitis particularly in immune compromised patients. Endophthalmitis is an inflammatory response typically due to an infection of the intraocular cavities. In reference specifically to P. curvatum, hypopyon (an accumulation of pus) as well as vitreous opacities are visible in patients with endophthalmitis. Reported sources of infection can include self intracavernous injections to treat erectile dysfunction as well as phacoemulsification.
In the examination of biomicroscopy, it appears as branches spread on the corneal stroma in the appearance of ghost vessels. diagnosis can also be confirmed with anterior segment OCT (visante OCT ,spetral domain OCT).The interwoven linear opaque filaments have some resemblance to NERVES, but may not be observed in all affected members of families with the condition. Recurrent corneal erosions may precede the corneal opacities and even appear in individuals lacking recognizable stromal disease.
No bacterial growth is seen around the discs that only contain either X or V factor. Chest X-ray of a case of Haemophilus influenzae, presumably as a secondary infection from influenza. It shows patchy consolidations, mainly in the right upper lobe (arrow). Chest X-ray in a case of COPD exacerbation where a nasopharyngeal swab detected Haemophilus influenzae: Opacities (on the patient's right side) can be seen in other types of pneumonia, as well.
Amine oxides (AO) are not known to be carcinogenic, dermal sensitizers or cause reproductive toxicity. They are readily metabolized and excreted if ingested. Chronic ingestion by rabbits found lower body weight, diarrhea, and lenticular opacities at a lowest observed adverse effect levels (LOAEL) in the range of 87–150 mg AO/kw bw/day. Tests of human skin exposure have found that after 8 hours less than 1% is absorbed into the body.
It can also be caused by severely dry eyes, a consequence of lower eyelid abnormalities and frequent eye infections. Although an abnormally shaped skull is not distinctive for Treacher Collins syndrome, brachycephaly with bitemporal narrowing is sometimes observed. Cleft palate is also common. Dental anomalies are seen in 60% of affected people, including tooth agenesis (33%), discoloration (enamel opacities) (20%), malplacement of the maxillary first molars (13%), and wide spacing of the teeth.
Aging causes laxity, downward shift of eyelid tissues and atrophy of the orbital fat. These changes contribute to the etiology of several eyelid disorders such as ectropion, entropion, dermatochalasis, and ptosis. The vitreous gel undergoes liquefaction (posterior vitreous detachment or PVD) and its opacities — visible as floaters — gradually increase in number. Various eye care professionals, including ophthalmologists (eye doctors/surgeons), optometrists, and opticians, are involved in the treatment and management of ocular and vision disorders.
There seems to be beneficial responses to clindamycin therapy as the lesions regress. This leads to the hypothesis that microorganisms may be playing a role in the initial stages of Kyrle disease. A family with Kyrle disease were examined which their skin lesions were benign. However, when three of the young adult members were closely examined, they had posterior subcapsular cataracts and two of those three developed multiple tiny yellow- brown anterior stromal corneal opacities.
For example, Peters anomaly is a rare disorder obtained during development characterized by adhesions due to malformations of the posterior corneal stroma, the absence of Descemet's membrane and the corneal endothelium, and corneal opacities. This syndrome can be attributed to fetal alcohol syndrome and aneuploidy. Scientists have generated a knockout model for Foxe3 in mice and are testing the effects on the lenses of those animals. So far, it appears that Foxe3 is essential for normal lens development.
Although both the symptoms and imaging findings are stereotypical and well-described, they are non-specific and indistinguishable from many other conditions. For example, chest x-ray may show alveolar opacities, and a CT may show a crazy paving lung pattern, both of which are seen more commonly in numerous other conditions. Thus, the diagnosis primarily depends on the pathology findings. Lung washings or tissue for histopathologic analysis are most commonly obtained using bronchoalveolar lavage and/or lung biopsy.
A layer of stratocumulus stratiformis perlucidus hiding the setting sun with a background layer of stratocumulus cumulogenitus resembling distant mountains. All cloud varieties fall into one of two main groups. One group identifies the opacities of particular low and mid-level cloud structures and comprises the varieties translucidus (thin translucent), perlucidus (thick opaque with translucent or very small clear breaks), and opacus (thick opaque). These varieties are always identifiable for cloud genera and species with variable opacity.
Pleural effusions are seen on CT in 12% of patients with S-LAM and 6% of patients with TSC-LAM. Other CT features include linear densities (29%), hilar or mediastinal lymphadenopathy (9%), pneumothorax, lymphangiomyoma, and thoracic duct dilation. Ground-glass opacities (12%) suggest the presence of interstitial edema due to lymphatic congestion. In patients with TSC, nodular densities on HRCT may represent multifocal micronodular pneumocyte hyperplasia (MMPH) made up of clusters of hyperplastic type II pneumocytes.
Rounded atelectasis (also known as Blesovsky’s or folded lung syndrome) develops from infolding of thickened visceral pleura with collapse of the intervening lung parenchyma. It presents radiographically as a mass and may be mistaken for a tumour. On a CT scan of the chest it appears as a rounded mass like opacity in the peripheral lung adjacent to thickened pleura and with curvilinear opacities which are the bronchi and vessels (comet tail).Batra, P., et al.
He traveled through Europe for six years, and painted in the Netherlands, Belgium, England, and Italy. In Europe, he mastered a type of watercolor where he achieved an abstract ambience, almost a pure abstraction with color that ranges from transparency to translucency, accompanied by strong opacities, and linear elements, always with a sense of freedom, which became one of his trademarks. In 1909, Marin held his first one-man exhibition at Alfred Stieglitz's 291 gallery in New York City.
It was formerly used to treat disorders, such as chronic hypertension, of the peripheral nervous system, which is innervated only by the sympathetic nervous system. The non-specificity of this treatment led to discontinuing its use. The use of inhaled hexamethonium, an unapproved drug, in a normal volunteer during a medical study is believed to have caused or contributed to her death in light of the presence of abnormal "ground glass opacities" on her chest X-ray.
Mucoid impaction of the upper and lower airways is a common finding. Plugs are hypodense but appear on CT with high attenuation (over 70 Hounsfield units) in up to 20% of patients. Where present it is a strong diagnostic factor of ABPA and distinguishes symptoms from other causes of bronchiectasis. CT scans may more rarely reveal mosaic-appearance attenuation, centrilobular lung nodules, tree-in-bud opacities and pleuropulmonary fibrosis (a finding consistent with CPA, a disease with ABPA as a known precursor).
Lisch epithelial corneal dystrophy (LECD), also known as band-shaped and whorled microcystic dystrophy of the corneal epithelium, is a rare form of corneal dystrophy first described in 1992 by Lisch et al. In one study it was linked to chromosomal region Xp22.3, with as yet unknown candidate genes. The main features of this disease are bilateral or unilateral gray band-shaped and feathery opacities. They sometimes take on a form of a whirlpool, repeating the known pattern of corneal epithelium renewal.
A crude practice of corneal tattooing was performed by Galen in 150 CE. He tried to cover leucomatous opacities of the cornea by cauterizing the surface with a heated stilet and applying powdered nutgalls and iron or pulverized pomegranate bark mixed with copper salt; the practice was revived in the 1800s. With the rise of Christianity, tattooing declined and eventually became banned by a papal edict in 787 CE. The practice of corneal tattooing was revived by Louis Von Wecker in the 1870s.
Opacity is generally calculated based on average opacities using Planck or Rosseland opacity functions. However, these averages generalize many one-electron transitions that can take place in a large number of atomic bound electron configurations. Harris' work was the first to calculate opacity including the full effects of line absorption. Edward Teller wrote in 1955 that Mayer worked with another student, John Reitz, and that they were supervised by Teller and by Frank Hoyt, a professor at the University of Chicago.
Characteristic imaging features on chest radiographs and computed tomography (CT) of people who are symptomatic include asymmetric peripheral ground-glass opacities without pleural effusions. The University of Montreal and Mila created the "COVID-19 Image Data Collection" in March which is a public data repository of chest imaging. The Medical Imaging Databank in Valencian Region released a large dataset of chest imaging from Spain. The Italian Radiological Society is compiling an international online database of imaging findings for confirmed cases.
Deprivation amblyopia (amblyopia ex anopsia) results when the ocular media become opaque, such as is the case with congenital cataract or corneal haziness. These opacities prevent adequate visual input from reaching the eye, and disrupt development. If not treated in a timely fashion, amblyopia may persist even after the cause of the opacity is removed. Sometimes, drooping of the eyelid (ptosis) or some other problem causes the upper eyelid to physically occlude a child's vision, which may cause amblyopia quickly.
The cause of asteroid hyalosis is unknown, but it has been associated with diabetes mellitus, hypertension, hypercholesterolemia, and, in certain animals, tumors of the ciliary body. In dogs, asteroid hyalosis is considered to be an age related change. The asteroid bodies are made up of hydroxylapatite, which in turn consists of calcium and phosphates or phospholipids. While asteroid hyalosis does not usually severely affect vision, the floating opacities can be quite annoying, and may interfere significantly with visualization and testing of the retina.
Pulmonary veno-occlusive disease can only be well diagnosed with a lung biopsy. CT scans may show characteristic findings such as ground-glass opacities in centrilobular distribution, and mediastinal lymphadenopathy, but these findings are non-specific and may be seen in other conditions. However, pulmonary hypertension (revealed via physical examination), in the presence of pleural effusion (done via CT scan) usually indicates a diagnosis of pulmonary veno-occlusive disease. The prognosis indicates usually a 2-year (24 month) life expectancy after diagnosis.
Aniseikonia can occur naturally or be induced by the correction of a refractive error, usually anisometropia (having significantly different refractive errors between each eye) or antimetropia (being myopic (nearsighted) in one eye and hyperopic (farsighted) in the other.) Meridional aniseikonia occurs when these refractive differences only occur in one meridian (see astigmatism). One cause of significant anisometropia and subsequent aniseikonia has been aphakia. Aphakic patients do not have a crystalline lens. The crystalline lens is often removed because of opacities called cataracts.
Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'.
" Critic Stephen Burt reviews Stolen Love Behaviour: "We know that a talented 21st-century English poet (Paul Farley, say) can render the 21st-century city in quick, ironic, breezy sketches. And we know that an extraordinarily talented 21st- century London poet (let's call him, for convenience, Mark Ford) can pursue the opacities of modern sociolects along with the bafflements of adult life. Can the same 21st-century poet do both? In cityscapes, domestic interiors, and briskly ironized variations on inherited language-games, John Stammers' second collection tries, and largely succeeds.
Epidemiological studies suggest an association between ocular cortical cataracts and UVB exposure, using crude approximations of exposure and various cataract assessment techniques. A detailed assessment of ocular exposure to UVB was carried out in a study on Chesapeake Bay Watermen, where increases in average annual ocular exposure were associated with increasing risk of cortical opacity. In this highly exposed group of predominantly white males, the evidence linking cortical opacities to sunlight exposure was the strongest to date. Based on these results, ozone depletion is predicted to cause hundreds of thousands of additional cataracts by 2050.
The diagnosis is made by the clinical picture and the chest X-ray, which demonstrates decreased lung volumes (bell-shaped chest), absence of the thymus (after about six hours), a small (0.5–1 mm), discrete, uniform infiltrate (sometimes described as a "ground glass" appearance or "diffuse airspace and interstitial opacities") that involves all lobes of the lung and air- bronchograms (i.e. the infiltrate will outline the larger airways passages, which remain air-filled). In severe cases, this becomes exaggerated until the cardiac borders become indiscernable (a 'white-out' appearance).
It is important to note that although there is difference in enamel translucency in the affected teeth, there should not be any changes to the enamel thickness, unlike in enamel hypoplasia. As a consequence, children with MIH are more likely to experience tooth decay compared to those without the condition. Moreover, the development of tooth decay is very rapid due to the less mineralised enamel. MIH only becomes visible once the permanent molars start to erupt and that is when opacities on the tooth can be observed if it is affected.
Patient remains asymptomatic until epithelial erosions precipitate acute episodes of ocular hyperemia, pain, and photophobia. Visual acuity eventually becomes reduced during the second and third decades of life following a progressive superficial haze and an irregular corneal surface. In Thiel–Behnke dystrophy, sub-epithelial corneal opacities form a honeycomb-shaped pattern in the superficial cornea. Multiple prominent gelatinous mulberry-shaped nodules form beneath the corneal epithelium during the first decade of life in Gelatinous drop-like corneal dystrophy which cause photophobia, tearing, corneal foreign body sensation and severe progressive loss of vision.
Lisch epithelial corneal dystrophy is characterized by feather shaped opacities and microcysts in the corneal epithelium that are arranged in a band-shaped and sometimes whorled pattern. Painless blurred vision sometimes begins after sixty years of life. Corneal stromal dystrophies - Macular corneal dystrophy is manifested by a progressive dense cloudiness of the entire corneal stroma that usually first appears during adolescence and eventually causing severe visual impairment. In Granular corneal dystrophy multiple small white discrete irregular spots that resemble bread crumbs or snowflakes become apparent beneath Bowman zone in the superficial central corneal stroma.
There are three basic criteria for the diagnosis of CWP: #Chest radiography consistent with CWP #An exposure history to coal dust (typically underground coal mining) of sufficient amount and latency #Exclusion of alternative diagnoses (mimics of CWP) Symptoms and pulmonary function testing relate to the degree of respiratory impairment but are not part of the diagnostic criteria. As noted above, the chest X-ray appearance for CWP can be virtually indistinguishable from silicosis. Chest CT, particularly high-resolution scanning (HRCT), are more sensitive than plain X-ray for detecting the small round opacities.
Winchester syndrome is a rare congenital connective tissue disease described in 1969, of which the main characteristics are short stature, marked contractures of joints, opacities in the cornea, coarse facial features, dissolution of the carpal and tarsal bones (in the hands and feet, respectively), and osteoporosis. Winchester syndrome was once considered to be related to a similar condition, multicentric osteolysis, nodulosis, and arthropathy (MONA). However, it was discovered that the two are caused by mutations found in different genes; they are now thought of as two separate disorders. Appearances resemble rheumatoid arthritis.
Atypical Gillespie syndrome associated with bilateral ptosis, exotropia, correctopia, iris hypoplasia, anterior capsular lens opacities, foveal hypoplasia, retinal vascular tortuosity, and retinal hypopigmentation. Neurological signs are nystagmus, mild craniofacial asymmetry, axial hypotonia, developmental delay, and mild mental retardation. Mariën P did not support the prevailing view of a global mental retardation as a cardinal feature of Gillespie syndrome but primarily reflect cerebellar induced neurobehavioral dysfunctions following disruption of the cerebrocerebellar anatomical circuitry that closely resembles the "cerebellar cognitive and affective syndrome" (CeCAS). Congenital pulmonary stenosis and helix dysplasia can be associated.
The main materials used in the construction of the building are concrete which comprises the structure of the tower and aluminium and glass in the form of 59,619 strips of painted sheet metal of different colours, covering the approximately 16,000 m2 of exterior surface. In addition, the glass has different inclinations and opacities which, combined with the different shades of aluminium, alter the colour balance of the tower as a function of time of day and season of the year. The construction used 25,000 m3 of concrete and 125 tonnes of steel.
CEV does not include entoptic phenomena such as "floaters", which are instead caused by opacities in the vitreous humour and often appear as cells or strands in the field of vision. Full-closing and reopening the eyelids creates a very definite wiper-ridge in the tear film that is readily visible. Fully closing and reopening the eyelids also often stirs up the vitreous which settles down after a brief moment due to gravity. The motion of waking-consciousness CEV noise is not so directly and physically controllable and repeatable.
There is preliminary epidemiological evidence that increasing lutein and zeaxanthin intake lowers the risk of cataract development. Consumption of more than 2.4 mg of lutein/zeaxanthin daily from foods and supplements was significantly correlated with reduced incidence of nuclear lens opacities, as revealed from data collected during a 13- to 15-year period in one study. Two meta-analyses confirm a correlation between high diet content or high serum concentrations of lutein and zeaxanthin and a decrease in the risk of cataract. There is only one published clinical intervention trial testing for an effect of lutein and zeaxanthin supplementation on cataracts.
The definition of contrast ratio is therefore re-stated as follows : 'The ratio between the opacities of the darkest and lightest points in the film image', thus: contrast ratio = Omax. / Omin. As we have already seen, opacity is not easily measured with standard photographic equipment—but the logarithm of opacity is continually measured since, in fact, it is the unit of image saturation known as density. Since density is a logarithm we must take the ratio of the anti-logarithms of the maximum and minimum densities in the image in order to arrive at the contrast ratio.
The technique of partial coherence interferometry measures the time required for infrared light to travel to the retina. Because light travels at too high a speed to be measured directly, light interference methodology is used to determine the transit time and thus the AL. This technique does not require contact with the globe, so corneal compression artifacts are eliminated. Compared with ultrasonography, the partial coherence interferometry provides more accurate, reproducible AL measurement. However, it is difficult to obtain a measurement in the presence of a dense cataract or other media opacities, which limits the use of this technique.
Degrees of vision loss vary dramatically, although the ICD-9 released in 1979 categorized them into three tiers: normal vision, low vision, and blindness. Two significant causes of vision loss due to sensory failures include media opacity and optic nerve diseases, although hypoxia and retinal disease can also lead to blindness. Most causes of vision loss can cause varying degrees of damage, from total blindness to a negligible effect. Media opacity occurs in the presence of opacities in the eye tissues or fluid, distorting and/or blocking the image prior to contact with the photoreceptor cells.
Typical zenith water opacities ranged from 0.10 to 0.15, with values as low as about 0.05 in the coldest, driest weather. A 1-second calibration is performed at the start of each scan to correct for short term variations of the receiver gain and atmospheric opacity. The observing season for the 1.2 m telescope, like other millimeter- wave telescopes at temperate northern latitudes, generally runs from October to May, with the best conditions in November through March. Cold, dry days afford the best observations, because of the decreased atmospheric opacity due to water vapor and the colder sky in general.
It will be positive in the event of exposure to D. immitis, so a cat that has successfully eliminated an infection may still be positive for up to three months. The antibody test is more sensitive than the antigen test, but it does not provide direct evidence of adult infection. It can, however, be considered specific for diagnosing previous larval infections, and therefore fairly specific for heartworm-associated respiratory disease. X-rays of the chest of a heartworm-infected cat may show an increased width of the pulmonary arteries and focal or diffuse opacities in the lungs.
Mice that have the lumican gene knocked out (Lum-/-) develop opacities of the cornea in both eyes and fragile skin. The lumican (LUM) gene was thought to be a candidate susceptibility gene for high myopia; however, a meta-analysis showed no association between LUM polymorphism and high myopia susceptibility in all genetic models studied. Lum knockout mice also have abnormal collagen in their heart tissue, with fewer and thicker fibrils. Mice deficient in both lumican and fibromodulin develop severe tendinopathy (tendon pathology), revealing the importance of these SLRPs in the development of correctly sized and aligned collagen fibers in tendon.
Lecithin–cholesterol acyltransferase (LCAT, also called phosphatidylcholine–sterol O-acyltransferase) is an enzyme that converts free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol), which is then sequestered into the core of a lipoprotein particle, eventually making the newly synthesized HDL spherical and forcing the reaction to become unidirectional since the particles are removed from the surface. The enzyme is bound to high-density lipoproteins (HDLs) (alpha-LCAT) and LDLs (beta-LCAT) in the blood plasma. LCAT deficiency can cause impaired vision due to cholesterol corneal opacities, anemia, and kidney damage. It belongs to the family of phospholipid:diacylglycerol acyltransferases.
A cataract is an opacity that develops in the crystalline lens of the eye. The word cataract literally means, "curtain of water" or "waterfall" as rapidly running water turns white, so the term may have been used metaphorically to describe the similar appearance between mature ocular opacities and water fall. The mechanism by which galactosemia causes cataract is not well understood, but the topic has been approached by researchers for decades, notably by the ophthalmologists, Jonas S. Friedenwald and Jin H. Kinoshita. Through this collective effort, a general mechanism for galactosemia's causation of presenile cataract has come into form.
Galen of Pergamum, a Roman physician and philosopher, first described corneal tattooing in 150 AD, and the same procedure was later described by Aetius in 450 AD as an attempt to mask the leucomatous opacities of the eye. Both physicians would cauterize the corneal surface with a heated stilet. After the cauterization, they would apply the dye to the eye, using a variety of dyes, such as powdered nutgalls and iron (see iron gall ink) or pulverized pomegranate bark mixed with copper salt. This would then stain the cornea, correcting the cosmetic appearance for the patient.
In laser thermal keratoplasty, a ring of concentric burns is made in the cornea, which causes its surface to steepen, allowing better near vision. ReLEx SMILE is the latest advancement in laser vision correction technology. In SMILE surgery, ZEISS VisuMax ® femtosecond laser is used to make a small incision and to create a pre-calculated mini lens tissue (or lenticule) inside the cornea. Lasers are also used to treat non-refractive conditions, such as phototherapeutic keratectomy (PTK) in which opacities and surface irregularities are removed from the cornea and laser coagulation in which a laser is used to cauterize blood vessels in the eye, to treat various conditions.
This will allow scientists to test and to further understand the functioning of the Sun (e.g., nuclear fusion processes taking place at the core of the Sun, solar composition, opacities, matter distribution, etc.) and will also help determine properties of neutrino oscillations, including the MSW effect. Specific goals of the experiment are to detect beryllium-7, boron-8, pp, pep and CNO solar neutrinos as well as anti-neutrinos from the Earth and nuclear power plants. The project may also be able to detect neutrinos from supernovae within our galaxy with a special potential to detect the elastic scattering of neutrinos onto protons, due to neutral current interactions.
Aldous Huxley Perhaps the most famous proponent of the Bates method was the British writer Aldous Huxley. At the age of 16, Huxley had an attack of keratitis, which, after an 18-month period of near-blindness, left him with one eye just capable of light perception and the other with an unaided Snellen fraction of 10/200. This was mainly due to opacities in both corneas, complicated by hyperopia and astigmatism. He was able to read only if he wore thick glasses and dilated his better pupil with atropine, to allow that eye to see around an opacity in the center of the cornea.
Keratoendotheliitis fugax hereditaria is an autosomal dominantly inherited disease of the cornea, caused by a point mutation in cryopyrin (also known as NALP3) that in humans is encoded by the NLRP3 gene located on the long arm of chromosome 1. In keratoendotheliitis fugax hereditaria, patients suffer from periodical transient inflammation of the corneal endothelium and stroma, leading to short term obscuration of vision and, in some patients after repeated attacks, to central corneal stromal opacities. Approximately 50 known cases have been reported in the literature. The disease so far has only been described from Finland, but exome databases suggest it may be more widely distributed in people of European ancestry.
Further clarification of ALDH3A1's role in the cornea has been provided by gene-knockout studies in which genes encoding ALDH3A1 were removed from the mice genome. It was found that ALDH3A1-null mice exhibited lower proteasome activity, higher rates of protein degradation/oxidation, and higher GSH, 4HNE and malondialdehyde protein adduct levels—all of which contributed to the development of cataracts and opacities in the subscapular regions of the cornea within one month of age. These observations on ALDH3A1-null mice reaffirm that ALDH3A1's role extends beyond enzymatic metabolism; encompassing functions in maintenance of the structural integrity and transparency of the cornea.
Type II alveolar cells have many important functions in the lung, including the production of pulmonary surfactant, maintenance of fluid balance and composition in the airspace. Phospholipids that make up pulmonary surfactant are broken down by macrophages, releasing phosphate into the alveolar lining fluid. The loss of the Npt2b phosphate transported eliminates the ability of alveolar type II cells to pump phosphorus ions from the alveolar space back into the bloodstream, and leads to microlith formation. Epithelial deletion of Npt2b in mice results in an authentic mimic of the human condition, including accumulation of calcium phosphate microliths in the lung tissue and progressive diffuse radiographic opacities.
Because the bases of the lungs lie posteriorly in the chest, a mild degree of collapse under the lungs' own weight can occur when the patient lies on their back. As the very base of the lungs may be the first region affected in several lung diseases, most notably asbestosis or usual interstitial pneumonia (UIP), the patient may be asked to lie prone to improve sensitivity to early changes of these conditions. The lung bases are often inconsistent in appearance in patients due to the potential for atelectasis causing positional ground glass or consolidative opacities. When the patient is positioned prone, or on their belly, the lung bases can expand further and help distinguish atelectasis from early fibrosis.
The yield of the Kraft process is only about 50%, which makes the demand of wood twice as high for the same amount of produced pulp Another benefit of the mechanical pulps is the excellent printing properties, making them very useful in newsprint and magazines. This is because of their good properties of absorbing the ink and also their high opacities and low area density. Chemimechanical pulps can give paper with high stiffness, making them suitable for paper board and as a stiff layer in paper packaging. The mechanical pulping processes have a high yield, which at the same time means that all the lignin is still present in the pulp and paper.
Consolidation and mucoid impaction are the most commonly described radiological features described in ABPA literature, though much of the evidence for consolidation comes from before the development of computed tomography (CT) scans. Tramline shadowing, finger-in-glove opacities and ‘toothpaste shadows’ are also prevalent findings. When utilising high- resolution CT scans, there can be a better assessment of the distribution and pattern of bronchiectasis within the lungs, and hence this is the tool of choice in the radiological diagnosis of ABPA. Central (confined to medial two- thirds of the medial half of the lung) bronchiectasis that peripherally tapers bronchi is considered a requirement for ABPA pathophysiology, though in up to 43% of cases there is a considerable extension to the periphery of the lung.
"Cataract" is derived from the Latin ', meaning "waterfall", and from the Ancient Greek ('), "down-rushing",καταρράκτης , Henry George Liddell, Robert Scott, A Greek-English Lexicon, on Perseus from καταράσσω (katarassō) meaning "to dash down"καταράσσω , Henry George Liddell, Robert Scott,A Greek-English Lexicon, on Perseus (from kata-, "down"; arassein, "to strike, dash"). As rapidly running water turns white, so the term may have been used metaphorically to describe the similar appearance of mature ocular opacities. In Latin, cataracta had the alternative meaning "portcullis"cataracta , Charlton T. Lewis, Charles Short, A Latin Dictionary, on Perseus and the name possibly passed through French to form the English meaning "eye disease" (early 15th century), on the notion of "obstruction".Online Etymology Dictionary , etymonline.
The ILO Classification system pertains to pulmonary parenchymal abnormalities (small and large opacities), pleural changes (pleural plaques, calcification, and diffuse pleural thickening) and other features associated, or sometimes confused, with occupational lung disease. The "Complete Set" of standard x-rays consists of 22 radiographs: two illustrating normal profusion, fifteen of differing profusion category and shape/size of small opacity (see below), three illustrating large opacity, one of "u"-sized small opacity, and one of various pleural abnormalities. The "Quad Set" consists of 14 radiographs, nine of the most commonly used standards from the Complete Set, plus five additional composite reproductions of quadrant sections from the other radiographs in the Complete Set. The film sets were new to coincide with the ILO (2000) Guidelines; the digital set is new and coincides with the 2011 Guidelines.
Main differential diagnosis include various causes of monoclonal gammopathy, lecithin-cholesterol-acyltransferase deficiency, Fabry disease, cystinosis, tyrosine transaminase deficiency, systemic lysosomal storage diseases, and several skin diseases (X-linked ichthyosis, keratosis follicularis spinolosa decalvans). Historically, an accumulation of small gray variable shaped punctate opacities of variable shape in the central deep corneal stroma immediately anterior to Descemet membrane were designated deep filiform dystrophy and cornea farinata because of their resemblance to commas, circles, lines, threads (filiform), flour (farina) or dots. These abnormalities are now known to accompany X-linked ichthyosis, steroid sulfatase deficiency, caused by steroid sulfatase gene mutations and are currently usually not included under the rubric of the corneal dystrophies. In the past, the designation vortex corneal dystrophy (corneal verticillata) was applied to a corneal disorder characterized by the presence of innumerable tiny brown spots arranged in curved whirlpool-like lines in the superficial cornea.
Kutner's two-layer model of the atmosphere parameterizes the elevation dependence of the correction factor in terms of only 3 parameters, each of which has a physical interpretation. Because oxygen has a much greater scale height than water vapor, the model assumes they can be considered separate layers, oxygen above water, with different characteristic temperatures and opacities. The temperature and opacity of oxygen in the upper atmosphere do not vary much seasonally and are assumed to be constant at 255 K and 0.378, respectively, at the signal frequency. The remaining parameters in the model, the temperature and opacity of water and the fraction of the received power from the sky, are determined through antenna tippings (measurements of the intensity of the sky signal as a function of elevation) at least once per six-hour observing shift, and more frequently if the weather is changing.
Active in helioseismology for over twenty years beginning in the early 1980s. The efforts in which he was involved include the first determinations of the Sun’s internal rotation, its internal differential rotation and determining limits on buried magnetic field and demonstrating that the Sun rotates on a single axis, determining the Sun’s seismic radius. Observationally, Goode led the effort that ultimately showed solar oscillations are driven, in part, by the noise made in the ubiquitous, continuous collapses of the dark inter-granular lanes. Also in the 1990s, he teamed to develop a seismic model of the Sun's interior, which was used to place strong limits on solar opacities and nuclear-reaction cross sections in the p-p chain, as well as demonstrating that there is no astrophysical solution to the sun’s neutrino deficit but rather the deficit is in the province of particle physics, which was subsequently shown experimentally.
The syndromes within CAPS overlap clinically, and patients may have features of more than one disorder. In a retrospective cohort of 136 CAPS patients with systemic involvement from 16 countries, the most prevalent clinical features were fever (84% of cases, often with concurrent constitutional symptoms such as fatigue, malaise, mood disorders or failure to thrive), skin rash (either urticarial or maculopapular rash; 97% of cases) especially after cold exposure, and musculoskeletal involvement (myalgia, arthralgia, and/or arthritis, or less commonly joint contracture, patellar overgrowth, bone deformity, bone erosion and/or osteolytic lesion; 86% of cases). Less common features included ophthalmological involvement (conjunctivitis and/or uveitis, or less commonly optic nerve atrophy, cataract, glaucoma or impaired vision; 71% of cases), neurosensory hearing loss (42% of cases), neurological involvement (morning headache, papilloedema, and/or meningitis, or less commonly seizure, hydrocephalus or mental retardation; 40% of cases), and AA amyloidosis (4% of cases). In keratoendotheliitis fugax hereditaria, systemic symptoms are not reported whereas the patients suffer from periodical transient inflammation of the corneal endothelium and stroma, leading to short term blurring of vision and, after repeated attacks, to central corneal stromal opacities in some patients.

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