" She insisted that the "singularity of the world's populations is not soluble merely in the market," while denouncing the "lies of globalization and liberalism.
|
|
Acyl chloride is not soluble in water. Instead, it decomposes in water.
|
|
Silver acetylide is not soluble in water and is not appreciably soluble in any other solvent.
|
|
It displays nephrotoxic effects to rats, but not to humans. It can be made from the compound trichloroethylene. Dichloroacetylene is not soluble in water.
|
|
Albumins are also globular proteins, although, unlike all of the other globular proteins, they are completely soluble in water. They are not soluble in oil.
|
|
Lithium fluoride (LiF) is the only alkali halide that is not soluble in water, and lithium hydroxide (LiOH) is the only alkali metal hydroxide that is not deliquescent.
|
|
For example, water and ethanol are miscible because they mix in all proportions. By contrast, substances are said to be immiscible if there are certain proportions in which the mixture does not form a solution. For one example, oil is not soluble in water, so these two solvents are immiscible. As another example, butanone (methyl ethyl ketone) is significantly soluble in water, but these two solvents are also immiscible because they are not soluble in all proportions.
|
|
Some of these anionic polyhydrides satisfy the 18-electron rule, many do not. Because of their high lattice energy, these salts are typically not soluble in any solvents, a well known exception being K2ReH9.
|
|
Citrus Red 2 is an orange to yellow solid or a dark red powder with a melting point of 156 °C. It is not soluble in water, but is readily soluble in many organic solvents.
|
|
The anionic substances often leave a form of calcium salts, which are not soluble, in the hair strands that causes hair to be dry and tangled. The alkaline residue may also cause hair and skin irritations.
|
|
However, it has been questioned as to whether tea made from A. annua is effective against malaria, since artemesinin is not soluble in water and the resulting tea would not be expected to contain any significant amount of artemesinin.
|
|
Journal of the International Hemp Association, 1997, 4(2):80-82. A colorless liquid, it is not soluble in water, but miscible with fats and oils. It is chiral, occurring naturally both as the racemate and enantio-enriched forms.
|
|
It is not soluble in water, though it will start dissolving in warm acid. Kurnakovite is usually colorless or white and either transparent or translucent. It has a vitreous, pearly luster and a refractive index of between 1.488 - 1.525.
|
|
Clobazam is a 1,5-benzodiazepine, meaning that its diazepine ring has nitrogen atoms at the 1 and 5 positions (instead of the usual 1 and 4). It is not soluble in water and is available in oral form only.
|
|
US Navy reactors and Boiling Water Reactors do not. Soluble poisons are also used in emergency shutdown systems. During SCRAM the operators can inject solutions containing neutron poisons directly into the reactor coolant. Various solutions, including sodium polyborate and gadolinium nitrate (Gd(NO3)3·H2O), are used.
|
|
However, CMC has also been misused in earlier work with cellulase enzymes, as many had associated whole cellulase activity with CMC hydrolysis. As the mechanism of cellulose depolymerization has become better understood, exo-cellulases are dominant in the degradation of crystalline (e.g. Avicel) and not soluble (e.g. CMC) cellulose.
|
|
It is not soluble in water, but it is soluble in acetone and many other organic solvents. Due to this property, dibutyl ether is used as solvent in various chemical reactions and processes. For example, phenyllithium is commercially available as a ca. 1.8 M solution in dibutyl ether.
|
|
Because of this arrangement, the interior of the toroids is not hydrophobic, but considerably less hydrophilic than the aqueous environment and thus able to host other hydrophobic molecules. In contrast, the exterior is sufficiently hydrophilic to impart cyclodextrins (or their complexes) water solubility. They are not soluble in typical organic solvents.
|
|
Roughly 20% comes from other heme sources, however, including ineffective erythropoiesis, and the breakdown of other heme-containing proteins, such as muscle myoglobin and cytochromes. The unconjugated bilirubin then travels to the liver through the bloodstream. Because this bilirubin is not soluble, it is transported through the blood bound to serum albumin.
|
|
Talc is translucent to opaque, with colors ranging from whitish grey to green with a vitreous and pearly luster. Talc is not soluble in water, and is slightly soluble in dilute mineral acids.Profiles of Drug Substances, Excipients and Related Methodology, Volume 36 p. 283 Soapstone is a metamorphic rock composed predominantly of talc.
|
|
Like asymmetrically disubstituted hydrazines, they are liquids, but their boiling points are typically higher. In particular, the aliphatic compounds are basic and reducing agents and are soluble in water. Aromatic symmetric disubstituted hydrazines are not soluble in water. Symmetrically disubstituted hydrazines are prepared by reducing nitro compounds under basic conditions or by reducing the azines.
|
|
If the number of glass and batch components is not equal, if it is impossible to exactly obtain the desired glass composition using the selected batch ingredients, or if the matrix equation is not soluble for other reasons (i.e., the rows/columns are linearly dependent), the batch composition must be determined by optimization techniques.
|
|
Pure avobenzone is a whitish to yellowish crystalline powder with a weak odor, dissolving in isopropanol, dimethyl sulfoxide, decyl oleate, capric acid/caprylic, triglycerides and other oils. It is not soluble in water. Avobenzone is a dibenzoylmethane derivative. Avobenzone exists in the ground state as a mixture of the enol and keto forms, favoring the chelated enol.
|
|
Sodium bismuthate is an inorganic compound, and a strong oxidiser. It is somewhat hygroscopic, but not soluble in cold water, which can be convenient since the reagent can be easily removed after the reaction. It is one of the few water insoluble sodium salts. Commercial samples may be a mixture of bismuth(V) oxide, sodium carbonate and sodium peroxide.
|
|
Although Mg2FeH6 is not soluble in ordinary solvents, related derivatives are. For example, the related salt Mg4Br4(THF)4FeH6 is soluble as are related alkoxides. Measurements on such compounds suggest that the hydride ligand exerts a weaker crystal field than cyanide.R.B. King "Structure and bonding in homoleptic transition metal hydride anions" Coordination Chemistry Reviews, 2000, vol.
|
|
Because pyrogens are often difficult to remove, inactivation or destruction of the LPS molecule can sometimes be preferable. ;Acid-base hydrolysis :This method has been shown to cleave Lipid A from the polysaccharide in the LPS molecule (see right). The lipid moiety alone is not soluble in water. Thus unable to bind to endothelial cells, it is rendered inactive.
|
|
Indigo is a challenging dye because it is not soluble in water. To be dissolved, it must undergo a chemical change (reduction). Reduction converts indigo into "white indigo" (leuco-indigo). When a submerged fabric is removed from the dyebath, the white indigo quickly combines with oxygen in the air and reverts to the insoluble, intensely colored indigo.
|
|
Aluminium (symbol Al) or aluminum (American English) is a silvery white member of the boron group of chemical elements and a p-block metal classified by some chemists as a post-transition metal.Huheey JE, Keiter EA & Keiter RL 1993, Principles of Structure & Reactivity, 4th ed., HarperCollins College Publishers, , p. 28 It is not soluble in water under normal circumstances.
|
|
Fish efficiently absorb methyl mercury, but excrete it very slowly. Methyl mercury is not soluble and therefore not excreted. Instead, it accumulates, primarily in the viscera, although also in the muscle tissue. This results in the bioaccumulation of mercury, in a buildup in the adipose tissue of successive trophic levels: zooplankton, small nekton, larger fish, and so on.
|
|
Shiso's distinctive flavor comes from perillaldehyde, which is found only in low concentrations in other perilla varieties, including Perilla frutescens. The oxime of perillaldehyde, perillartine, is about 2,000 times sweeter than sucrose. However, perillartine has a bitter aftertaste and is not soluble in water, and is only used in Japan as an artificial sweetener to sweeten tobacco.Kinghorn and Compadre (2001) apud .
|
|
Though it is not soluble in water (0.003%% solubility), aldrin dissolves very well in organic solvents, such as ketones and paraffins. Aldrin decays very slowly once released into the environment. Though it is rapidly converted to dieldrin by plants and bacteria, dieldrin maintains the same toxic effects and slow decay of aldrin. Aldrin is easily transported through the air by dust particles.
|
|
Zirconium propionate is a white powder with molecular formula Zr(CH3CH2COO)4. Its structure is complex, but is believed to be based on hydroxy-bridged zirconium polymers, with the propionate carboxyl group bonded to the zirconium. Propionates are salts or esters of propionic acid. It is not soluble in water, but dissolves in a solution of isopropanol, ethanol and ethyl acetate.
|
|
Biliverdin dimethyl ester, biliverdin, and phycocyanobilin are commercially available from Frontier Scientific. Biliverdin dimethyl ester, biliverdin, or phycocyanobilin is dissolved in DMSO at a concentration of 5 mM. The solution is very dark and pipette vigorously to ensure all is dissolved. Biliverdin dimethyl ester is not soluble in common buffers, including phosphate buffered saline (PBS) or Hank's balanced salt solution (HBSS).
|
|
The powder is placed inside a pycnometer of known volume, and weighed. The Pycnometer is then filled with a fluid of known density, in which the powder is not soluble. The volume of the powder is determined by the difference between the volume as shown by the pycnometer, and the volume of liquid added (i.e. the volume of air displaced).
|
|
Vanadyl acetylacetonate is the chemical compound with the formula VO(acac)2, where acac– is the conjugate base of acetylacetone. It is a blue-green solid that dissolves in polar organic solvents. The coordination complex consists of the vanadyl group, VO2+, bound to two acac– ligands via the two oxygen atoms on each. Like other charge-neutral acetylacetonate complexes, it is not soluble in water.
|
|
Lithium hydride is an inorganic compound with the formula LiH. This alkali metal hydride is a colorless solid, although commercial samples are grey. Characteristic of a salt-like (ionic) hydride, it has a high melting point, and it is not soluble but reactive with all organic and protic solvents. It is soluble and nonreactive with certain molten salts such as lithium fluoride, lithium borohydride, and sodium hydride.
|
|
Regardless, vitrinite is not soluble in water and could therefore only contaminate fire features in the stratum as particulate matter. Repeated examination of the radiocarbon samples by four different laboratories has consistently failed to reveal any particulate fragments. Additionally, microstratigraphic analyses by Paul Goldberg and associates has conclusively indicated absolutely no groundwater movement and hence, no vehicle for transporting contaminants in any of the sites 11 strata.
|
|
Protoporphyrin IX is an organic compound, specifically a porphyrin, that plays an important role in living organisms as a precursor to other critical compounds like hemoglobin and chlorophyll. It is a deeply colored solid that is not soluble in basic water. The name is often abbreviated as PPIX. The Protoporphyrin IX molecule contains the porphine core, a tetrapyrrole macrocycle that shows marked aromatic character.
|
|
A typical laboratory technique for crystal formation is to dissolve the solid in a solution in which it is partially soluble, usually at high temperatures to obtain supersaturation. The hot mixture is then filtered to remove any insoluble impurities. The filtrate is allowed to slowly cool. Crystals that form are then filtered and washed with a solvent in which they are not soluble, but is miscible with the mother liquor.
|
|
Because the long linear chains of amylose more readily crystallize than amylopectin (which has short, highly branched chains), high-amylose starch is more resistant to digestion. Unlike amylopectin, amylose is not soluble in cold water. It also reduces the crystallinity of amylopectin and how easily water can infiltrate the starch. The higher the amylose content, the less expansion potential and the lower the gel strength for the same starch concentration.
|
|
This reaction is exploited in the Claus process, an important industrial method to dispose of hydrogen sulfide. Hydrogen sulfide is slightly soluble in water and acts as a weak acid (pKa = 6.9 in 0.01–0.1 mol/litre solutions at 18 °C), giving the hydrosulfide ion (also written ). Hydrogen sulfide and its solutions are colorless. When exposed to air, it slowly oxidizes to form elemental sulfur, which is not soluble in water.
|
|
The impact strength of styrene-butadiene co-polymers is based on phase separation, polystyrene and poly-butane are not soluble in each other (see Flory-Huggins theory). Co- polymerization creates a boundary layer without complete mixing. The butadiene fractions (the "rubber phase") assemble to form particles embedded in a polystyrene matrix. A decisive factor for the improved impact strength of styrene-butadiene copolymers is their higher absorption capacity for deformation work.
|
|
Where dissolution of the acid copolymer is difficult, simply swelling the polymer in the solvent is sufficient, though dissolving is always preferred. Because basic salts are polar and are not soluble in the non-polar solvents used to dissolve most polymers, mixed solvents (e.g. 90:10 toluene/alcohol) are often used. Neutralization level must be determined after an ionomer is synthesized as varying the neutralization level varies the morphological and physical properties of the ionomer.
|
|
Synthetic chlorophyll is registered as a food additive colorant, and its E number is E140. Chefs use chlorophyll to color a variety of foods and beverages green, such as pasta and spirits. Absinthe gains its green color naturally from the chlorophyll introduced through the large variety of herbs used in its production. Chlorophyll is not soluble in water, and it is first mixed with a small quantity of vegetable oil to obtain the desired solution.
|
|
The (1→3)-linkages break up the uniform structure of the beta-D-glucan molecule and make it soluble and flexible. In comparison, the indigestible polysaccharide cellulose is also a beta-glucan, but is not soluble because of its (1→4)-beta-D-linkages. The percentages of beta-glucan in the various whole oat products are: oat bran, having from 5.5% to 23.0%; rolled oats, about 4%; and whole oat flour about 4%.
|
|
Mixtures of substances that are not soluble are usually readily separated by physical sieving or settlement. However mixtures can have different properties from the individual components. One familiar example is the mixture of fine sand with water used to make sandcastles. Neither the sand on its own nor the water on its own will make a sand-castle but by using physical properties of surface tension, the mixture behaves in a different way.
|
|
Technetium exhibits nine oxidation states from −1 to +7, with +4, +5, and +7 being the most common. Technetium dissolves in aqua regia, nitric acid, and concentrated sulfuric acid, but it is not soluble in hydrochloric acid of any concentration. Metallic technetium slowly tarnishes in moist air and, in powder form, burns in oxygen. Technetium can catalyse the destruction of hydrazine by nitric acid, and this property is due to its multiplicity of valencies.
|
|
Suspension polymerization is divided into two main types, depending on the morphology of the particles that result. In bead polymerization, the polymer is soluble in its monomer and the result is a smooth, translucent bead. In powder polymerization, the polymer is not soluble in its monomer and the resultant bead will be porous and irregular. The morphology of the polymer can be changed by adding a monomer diluent, an inert liquid that is insoluble with the liquid matrix.
|
|
For most drug compound libraries, where many compounds are not soluble beyond ~100 μM, screening multiple compounds is consequently not feasible owing to solubility issues. Thermofluor screens do not require the development of custom screening reagents (e.g. cleavable substrate analogs), do not require any radioactive reagents, and are generally less sensitive to the effects of compounds that are chemically reactive with protein active site residues, and that consequently show up as undesirable hits in enzyme activity screens.
|
|
Some fullerene structures are not soluble because they have a small band gap between the ground and excited states. These include the small fullerenes , and . The structure is also in this class, but the endohedral version with a trapped lanthanide-group atom is soluble due to the interaction of the metal atom and the electronic states of the fullerene. Researchers had originally been puzzled by being absent in fullerene plasma-generated soot extract, but found in endohedral samples.
|
|
Neptunium(III) hydroxide is quite stable in acidic solutions and in environments that lack oxygen, but it will rapidly oxidize to the IV state in the presence of air. It is not soluble in water. Np(IV) hydroxides exist mainly as the electrically neutral Np(OH)4 and its mild solubility in water is not affected at all by the pH of the solution. This suggests that the other Np(IV) hydroxide, , does not have a significant presence.
|
|
Hansen observed a number of nonrefractile small rods in unstained tissue sections. The rods were not soluble in potassium lye, and they were acid- and alcohol-fast. In 1879, he stained these organisms with Ziehl's method and noted the similarities with Koch's bacillus (Mycobacterium tuberculosis). There were three significant differences between these organisms: (1) the rods in the leprosy lesions were extremely numerous, (2) they formed characteristic intracellular collections (globii), and (3) the rods had a variety of shapes with branching and swelling.
|
|
When this occurs, the number of moles of hydroxypropyl groups per glucose ring, moles of substitution (MS), can be higher than 3. Because cellulose is very crystalline, HPC must have an MS about 4 in order to reach a good solubility in water. HPC has a combination of hydrophobic and hydrophilic groups, so it has a lower critical solution temperature (LCST) at 45 °C. At temperatures below the LCST, HPC is readily soluble in water; above the LCST, HPC is not soluble.
|
|
The phosphate ion has a molar mass of 94.97 g/mol, and consists of a central phosphorus atom surrounded by four oxygen atoms in a tetrahedral arrangement. It is the conjugate base of the hydrogen phosphate ion , which in turn is the conjugate base of the dihydrogen phosphate ion , which in turn is the conjugate base of orthophosphoric acid, . Many phosphates are not soluble in water at standard temperature and pressure. The sodium, potassium, rubidium, caesium, and ammonium phosphates are all water-soluble.
|
|
Ultraviolet light and cathode rays have no fluorescent effect on changbaiite and this is not soluble in hydrochloric acid, nitric acid or sulphuric acid but conditionally less soluble in hot phosphoric acid. Changbaiite has a hardness of 472.4 kg/mm2 on the Vickers hardness scale and 5.3 on mohs scale. In an optical spectrum changbaiite is uniaxial positive and it can be biaxial. Changbaiite reflectance, which is the fraction of incident radiation reflected by a surface, is 15.86 at 546 nm.
|
|
Potassium bromide (KBr) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries, with over-the-counter use extending to 1975 in the US. Its action is due to the bromide ion (sodium bromide is equally effective). Potassium bromide is used as a veterinary drug, as an antiepileptic medication for dogs. Under standard conditions, potassium bromide is a white crystalline powder. It is freely soluble in water; it is not soluble in acetonitrile.
|
|
As described in The Hidden Hand by Richard Aldrich on page 414, Soviet troops were not issued toilet paper in the field. This led them to use official documents as toilet paper. The US, UK and France then used their spies to retrieve the documents as the paper was not soluble and was put into bins. The spies actually complained to their handlers that they had to go through the bins that contained fecal matter and even amputated limbs, in the case of hospital rubbish bins.
|
|
Lipophobicity, also sometimes called lipophobia (from the Greek λιποφοβία from λίπος lipos "fat" and φόβος phobos "fear"), is a chemical property of chemical compounds which means "fat rejection", literally "fear of fat". Lipophobic compounds are those not soluble in lipids or other non-polar solvents. From the other point of view, they do not absorb fats. "Oleophobic" (from the Latin oleum "oil", Greek ελαιοφοβικό eleophobico from έλαιο eleo "oil" and φόβος phobos "fear") refers to the physical property of a molecule that is seemingly repelled from oil.
|
|
Ordinary bone wax is effective by virtue of its tamponade action, but is considered to have no active hemostatic properties (i.e. does not activate the blood clotting cascade). In addition, bone wax is not soluble in the bodily fluids and thus remains at the site of implantation for long periods of time, if not indefinitely. The portion of traditional bone wax that departs the implant site is most likely carried away through the action of the foreign body response and is associated with a low-grade inflammatory response at and near the implant site.
|
|
Amino acid general structure The Murchison meteorite is on display at the Smithsonian’s NMNH. Carbonaceous chondrites contain more than 600 organic compounds that were synthesized in distinct places and at distinct times. These organic compounds include: hydrocarbons, carboxylic acids, alcohols, ketones, aldehydes, amines, amides, sulfonic acids, phosphonic acids, amino acids, nitrogenous bases, etc. These compounds can be divided into three main groups: a fraction that is not soluble in chloroform or methanol, chloroform soluble hydrocarbons and a fraction that is soluble in methanol (which includes the amino acids).
|
|
Homogenization (from "homogeneous;" Greek, homogenes: homos, same + genos, kind)homo-, word origin is the process of converting two immiscible liquids (i.e. liquids that are not soluble, in all proportions, one in another) into an emulsion (Mixture of two or more liquids that are generally immiscible). Sometimes two types of homogenization are distinguished: primary homogenization, when the emulsion is created directly from separate liquids; and secondary homogenization, when the emulsion is created by the reduction in size of droplets in an existing emulsion. Homogenization is achieved by a mechanical device called a homogenizer.
|
|
Schiller's focus became his opposition to formal logic. To understand Schiller's opposition to formal logic, consider the following inference: ::(1) All salt is soluble in water; ::(2) Cerebos is not soluble in water; ::(3) Therefore, Cerebos is not a salt. From the formal characteristics of this inference alone (All As are Bs; c is not a B; Therefore, c is not an A), formal logic would judge this to be a valid inference. Schiller, however, refused to evaluate the validity of this inference merely on its formal characteristics.
|
|
Non-polar compounds would not be influenced by the hydroxyls on the surface of the paper, but because of their hydrophobic nature may not diffuse through the aqueous medium resulting in false negatives. Large molecules also often diffuse poorly. Thus, some antimicrobial compounds may not be identified using a disc diffusion assay. On the other hand, the accuracy of the MTT microdilution assay can be compromised by samples that are coloured (such as plant extracts), redox active and/or samples that are not soluble in the medium, which is predominantly aqueous.
|
|
Hexafluoro-propan-2-ol is prepared from hexafluoropropylene through hexafluoroacetone, which is then hydrogenated.Günter Siegemund, Werner Schwertfeger, Andrew Feiring, Bruce Smart, Fred Behr, Herward Vogel, Blaine McKusick “Fluorine Compounds, Organic” in Ullmann's Encyclopedia of Industrial Chemistry, John Wiley & Sons, 2007. :(CF3)2CO + H2 → (CF3)2CHOH Hexafluoro- propan-2-ol is a speciality solvent for some polar polymers and organic synthesis. It is especially effective for solubilizing a wide range of polymers, including those that are not soluble in the most common organic solvents, such as: polyamides, polyacrylonitriles, polyacetals, polyesters (e.g.
|
|
This was the initial model, used for collection of airs by combustion. The pneumatic trough, while integral throughout the eighteenth century, was modified several times to collect gases more efficiently or just to collect more gas. For example, Cavendish noted that the amount of fixed air that was given off by a reaction was not entirely present above the water; this meant that fixed water was absorbing some of this air, and could not be used quantitatively to collect that particular air. So, he replaced the water in the trough with mercury instead, in which most airs were not soluble.
|
|
While this might sound like a large amount it has only resulted in a very small dose to the majority of the humans on the earth. Overall the health effects of fission products are far greater than the effects of the actinides released by a nuclear bomb detonation. The plutonium from the fuel of the bomb is converted into a high-fired oxide that is carried high into the air. It slowly falls to earth as global fallout and is not soluble, and as a result it is difficult for this plutonium to be incorporated into an organism if ingested.
|
|
In corrosion, spalling occurs when a substance (metal or concrete) sheds tiny particles of corrosion products as the corrosion reaction progresses. Although they are not soluble or permeable, these corrosion products do not adhere to the parent material's surface to form a barrier to further corrosion, as happens in passivation. Spallation happens as the result of a large volume change during the reaction. In the case of actinide metals (most notably the depleted uranium used in some types of ammunition), the material expands so strongly upon exposure to air that a fine layer of oxide is forcibly expelled from the surface.
|
|
A light non-aqueous phase liquid (LNAPL) is a groundwater contaminant that is not soluble in water and has lower density than water, in contrast to a DNAPL which has higher density than water. Once a LNAPL infiltrates the ground, it will stop at the height of the water table because the LNAPL is less dense than water. Efforts to locate and remove LNAPLs is relatively less expensive and easier than for DNAPLs because LNAPLs float on top of the water in the underground water table. Examples of LNAPLs are benzene, toluene, xylene, and other hydrocarbons.
|
|
Not knowing that this visit was about the missing dog, he assumed that he was to be arrested, and so shot himself. His audience is stunned at the accusation that Capel was a murderer, objecting that he was not at the Appleton home on the day of the death; but Quin points out that strychnine is not soluble and would collect at the bottom of the decanter if placed there a week before. Why did Mrs Appleton smash the decanter? At Quin's prompting, Satterthwaite theorises it was to protect Capel, not to cover her own guilty tracks.
|
|
Before the first World War most speed records were gained using Gnome-engined aircraft, and in the early years of the war rotary engines were dominant in aircraft types for which speed and agility were paramount. To increase power, engines with two rows of cylinders were built. However, the gyroscopic effects of the heavy rotating engine produced handling problems in aircraft and the engines also consumed large amounts of oil since they used total loss lubrication, the oil being mixed with the fuel and ejected with the exhaust gases. Castor oil was used for lubrication, since it is not soluble in petrol, and the resultant fumes were nauseating to the pilots.
|
|
The RNA-dependent RNA polymerase that replicates both the positive and negative RNA strands is a complex of four proteins: the catalytic beta subunit (replicase, ) is encoded by the phage, while the other three subunits are encoded by the bacterial genome: alpha subunit (ribosomal protein S1), gamma subunit (EF-Tu), and delta subunit (EF-Ts). The structure of the Qbeta RNA replicase has been solved (). The two EF proteins serve as a chaperone for both the replicase and the RNA product. In fact, pure Qbeta polymerase is not soluble enough to be produced in large quantities, and a fusion protein constructed from the replicase and the two EF subunits is usually used instead.
|
|
Using ultraviolet–visible spectroscopy to study its reactions with phenol groups, after treating the samples with alkali, although the absorption curve initially showed no changes, it was observed to have shifted to higher absorption readings if one or more of the hydroxy groups were unpaired. Basing further research on this observation, Pedersen then dipped the unknown product in methanoland sodium hydroxide. Although the solution was not soluble in methanol, it became alkaline when in contact with the sodium hydroxide. thumb Due to not being soluble in methanol, Pedersen then proceeded to treat the methanol with soluble sodium salts, to which the unknown substance became soluble, allowing him to conclude that the solubility was due to sodium ions instead of alkalinity.
|
|
Artemisinin is a sesquiterpene lactone with an endoperoxide bridge and has been produced semisynthetically as an antimalarial drug. The efficacy of tea, made with either water or urine and A. annua, for the treatment of malaria is dubious, and is discouraged by the World Health Organization (WHO). Research has found that artemesinin is not soluble in water and the concentrations in these infusions are considered insufficient to treat malaria. In 2004, the Ethiopian Ministry of Health changed Ethiopia's first line antimalaria drug from sulfadoxine/pyrimethamine (Fansidar), which has an average 36% treatment failure rate, to artemether/lumefantrine (Coartem), a drug therapy containing artemesinin which is 100% effective when used correctly, despite a worldwide shortage at the time of the needed derivative from A. annua.
|
|
Methyl cellulose has a lower critical solution temperature (LCST) between 40 °C and 50 °C. At temperatures below the LCST, it is readily soluble in water; above the LCST, it is not soluble, which has a paradoxical effect that heating a saturated solution of methyl cellulose will turn it solid, because methyl cellulose will precipitate out. The temperature at which this occurs depends on DS-value, with higher DS-values giving lower solubility and lower precipitation temperatures because the polar hydroxyl groups are masked. Preparing a solution of methyl cellulose with cold water is difficult however: as the powder comes into contact with water, a gel layer forms around it, dramatically slowing the diffusion of water into the powder, hence the inside remains dry.
|
|