2 Sentences With "most epidemic"

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Over the past 50,000–100,000 years, as modern humans increased in numbers and dispersed throughout the world, new infectious diseases emerged, including those caused by viruses. Earlier, humans lived in small, isolated communities, and most epidemic diseases did not exist.Clark, p. 56Barrett and Armelagos, p. 28 Smallpox, which is the most lethal and devastating viral infection in history, first emerged among agricultural communities in India about 11,000 years ago.
How was it then that diseases native to the American continents did not kill off Europeans? Diamond posits that most of these diseases were only developed and sustained in large dense populations in villages and cities; he also states most epidemic diseases evolve from similar diseases of domestic animals. The combined effect of the increased population densities supported by agriculture, and of close human proximity to domesticated animals leading to animal diseases infecting humans, resulted in European societies acquiring a much richer collection of dangerous pathogens to which European people had acquired immunity through natural selection (see the Black Death and other epidemics) during a longer time than was the case for Native American hunter- gatherers and farmers. He mentions the tropical diseases (mainly malaria) that limited European penetration into Africa as an exception.