56 Sentences With "most efficacious" | Random Sentence Generator

At that point it's about helping owners "use the safest products and most efficacious products on their pets," she said.

This one time comprehensive care planning session will arm patients and caregivers with the facts, prognosis, and most efficacious treatment plan.

Exercise is the most efficacious drug known to humankind, works for everyone who takes it, has no side effects, and is free.

Fascists were also convinced that "the people" were best off, and politics most efficacious, when led by a strong ruler or a committed minority.

Regardless of modern placards, the World Health Organization lists ketamine as an "essential medicine," and among the safest and most efficacious ones known to science.

The WHO describes ketamine as among " …the most efficacious, safe and cost–effective medicines for priority conditions" and recommends ready availability in every medical system.

"If you have a mood or anxiety disorder, many excellent treatments are available; the most efficacious is some form of cognitive-behavior therapy with or without medication," she said.

Fighting the last war is a venerable tradition in both politics and the military, but it's seldom the most efficacious approach to ensuring victory in either mode of combat.

These medicines are defined as "minimum medicine needs for a basic health-care system, listing the most efficacious, safe and cost-effective medicines for priority conditions," according to the WHO.

WE MAY HAVE OUR DISCUSSIONS REGARDING TRADE AND OTHER MATTERS, WHAT'S THE BEST MOST EFFICACIOUS WAY TO GENERATE THE KIND OF ECONOMIC GROWTH POLICIES AND SOLVE THE WORLD TRADING BALANCES.

The thick cream contains bi-floral cells — a fancy way of saying that scientists took the best, most efficacious cells from two plants and combined them into one supercell that took over the world.

Consider the Choice Project in St. Louis and the Colorado Family Planning Initiative, two large-scale programs focused on providing the most efficacious forms of contraception, long-acting reversible contraception (LARC) like IUDs and implants.

"No criticism intended," Burroughs said at one point to Harvard's leading data witness as he was criticizing the challengers' interpretation, "but I assume that you're both presenting the data in the way that's most efficacious for your models."

But the larger and more interesting group to discuss is the significant portion of American parents who say they believe in vaccines but just don't want them for their children — or don't want all the vaccines that experts insist are safest and most efficacious.

"ECT is the single most efficacious treatment that we have and the treatment of choice if you absolutely had to get someone out of a severe depression within a day or two," said Steven D. Hollon, a professor of psychology at Vanderbilt University, who has studied the treatment of depression.

The answer, in short, is more politics: a political system that is fluid and competitive; A system that leverages diversity and creates opportunity for experimentation and change; A political system that expands, not limits, the combinatorial possibilities of political innovation and deal-making; A political system that helps citizens to aggregate and realize their interests in the most efficacious ways, rather than simultaneously expecting them to be super-engaged and expert while giving them few meaningful choices.

If I may quote myself for a moment: The answer, in short, is more politics: a political system that is fluid and competitive; a system that leverages diversity and creates opportunity for experimentation and change; a political system that expands, not limits, the combinatorial possibilities of political innovation and deal-making; a political system that helps citizens to aggregate and realize their interests in the most efficacious ways, rather than simultaneously expecting them to be super-engaged and expert while giving them few meaningful choices.

At this stage, antibiotics are most efficacious to prevent further growth and symptoms of the disease before the major symptoms manifest.

Application of the tissue-molding device at 1-week after the child's birth proved most efficacious in achieving a successful correction, because, when the correction was initiated at 3-weeks from birth, the lessened malleability of the cartilage and tissues of the ear reduced the successful deformity correction rate to 50 per cent.

Despite the name, the diezmo was not always exactly ten percent. The actual amount differed in different places and times. Nor was it extended to all products of agriculture and husbandry, which led to market distortions as farmers shifted to whatever was not taxed. The most efficacious measure against fraud was excommunication, which would remain in place until one's debt was paid.

4-Benzylpiperidine is a drug and research chemical used in scientific studies. It acts as a monoamine releasing agent with 20- to 48-fold selectivity for releasing dopamine versus serotonin. It is most efficacious as a releaser of norepinephrine, with an ec50 of 109/41.4/5246nM for DA/NE/5HT, respectively . It has a fast onset of action and a short duration.

Academic research has yielded some generalizable results on the effects of upzoning, the root causes of unaffordability, and the most efficacious policy prescriptions to help low-income workers in prosperous cities. However, scholars have said more research is necessary to determine the full effects of upzoning and market-rate housing development on affordability for all income levels in prosperous cities.

Naam Ghosa () is a Vaishnavite scripture of verses in praise of Lord Krishna. This book was written by Madhabdev in Assamese in about 1568–1596. It extols the practice of chanting the name of the deity as the most efficacious means of devotion. The English version of this book subtitled as The Divine Verses translated by Soroj Kumar Dutta in 1997.

The standard of care is administration of antifilarial drugs, most commonly Ivermectin or diethyl-carbamazine (DEC). The most efficacious dose in all nematode and parasitic infections is 200 μg/kg of ivermectin. There has also been other various anthelminthic drugs used, such as mebendazole, levamisole, albendazole and thiabendazole. In worst-case scenarios, surgery may be necessary to remove nematodes from the abdomen or chest.

In the late 19th century, the most efficacious remedies were: fumigations with sulphur for several evenings in succession while the grain was in blossom, lime and ashes strewn over them when wet with dew, liming and ploughing the soil into which they have burrowed, and sowing late in spring or early in autumn. A little black ichneumon fly deposits her eggs within these larvae, and destroys many.

The plasma is then further processed to produce a final product approximately 8 times the concentration found in the blood. This final product can be produced in under an hour, making it possible to treat the lesion immediately. PRP is most efficacious when used in acute lesions within 10 days of original injury. Because PRP contains white blood cells, injection of the product has been associated with inflammation following treatment.

There currently is no established guideline for the standardised treatment of malignant chondroid syringomas, due to their rarity. However, the efficacy of treatment for malignant mixed tumours depends on the time of diagnosis. An immediate and broad surgical excision "with clear margins" (Tural, Selçukbiricik, Günver, Karışmaz, and Serdengecti, 2013) is considered curative and to be the most successful treatment. This treatment aims for the most efficacious disease control.

Fairey created a series of posters supporting Barack Obama's 2008 candidacy for President of the United States, including the iconic "HOPE" portrait. The New Yorker art critic Peter Schjeldahl called the poster "the most efficacious American political illustration since 'Uncle Sam Wants You'". Fairey also created an exclusive design for Rock the Vote. Because the Hope poster had been "perpetuated illegally" and independently by the street artist, the Obama campaign declined to have any direct affiliation with it.

There are various forms of topical retinoids. Tretinoin, a retinoid, is widely considered to be the most efficacious treatment for photoaging by dermatologists due to consistent evidence from several randomized clinical trials. Retinoids are vitamin A derivatives that bind to retinoic acid receptors (RARs) and retinoid X receptors (RXRs). Binding to these receptors induces a cascade of cellular processes that ultimately lead to increased collagen production and epidermal thickening, reducing the appearance of skin sagging and wrinkling.

Most treatment for problem gambling involves counseling, step-based programs, self-help, peer-support, medication, or a combination of these. However, no one treatment is considered to be most efficacious and, in the United States, no medications have been approved for the treatment of pathological gambling by the U.S. Food and Drug Administration (FDA). Gamblers Anonymous (GA) is a commonly used treatment for gambling problems. Modeled after Alcoholics Anonymous, GA is a twelve-step program that emphasizes a mutual-support approach.

Albertini, Rudolph von, and Wirz, Albert. European Colonial Rule, 1880-1914: The Impact of the West on India, South East Asia and Africa Historians L. H. Gann and Peter Duignan have also argued that Africa probably benefited from colonialism on balance. Although it had its faults, colonialism was probably "one of the most efficacious engines for cultural diffusion in world history".Lewis H. Gann and Peter Duignan, The Burden of Empire: An Appraisal of Western Colonialism South of the Sahara (1967).

The mainstays of treatment are the administration of broad-spectrum antibiotics (typically potentiated sulfonamides or penicillin and streptomycin, but doxycycline may be the most effective). If possible, microbial culture and sensitivity testing should be performed, so the most efficacious antibiotic can be chosen. However, intracellular organisms such as Corynebacterium pseudotuberculosis will be susceptible to certain antibiotics in vitro that are not effective for the specific organism in the horse. These horses are typically treated with rifampin in addition to one of the previously mentioned antibiotics.

Oximes remove the phosphoryl group bound to the active site of the AChE by binding to it. There are a few oximes that are the most efficacious by AzM poisoning, namely oxime K-27 and physostigmine. These two treatments are also used together, some patients are namely treated with atropine (a competitive antagonist of AChE) and reactivating oximes. When patients are resistant to atropine, the patients can be treated with low doses of anisodamine, a cholinergic and alpha-1 adrenergic antagonist, to achieve a shorter recovery time.

Breast cancer management takes different approaches depending on physical and biological characteristics of the disease, as well as the age, over-all health and personal preferences of the patient. Treatment types can be classified into local therapy (surgery and radiotherapy) and systemic treatment (chemo-, endocrine, and targeted therapies). Local therapy is most efficacious in early stage breast cancer, while systemic therapy is generally justified in advanced and metastatic disease, or in diseases with specific phenotypes. Historically, breast cancer was treated with radical surgery alone.

There are various Hindu tantric traditions within Shaivism, Shaktism and Vaishnavism. There are numerous tantric texts for these different traditions with different philosophical point of views, ranging from theistic dualism to absolute monism.Richard Davis (2014), Ritual in an Oscillating Universe: Worshipping Siva in Medieval India, Princeton University Press, , page 167 note 21, Quote (page 13): "Some agamas argue a monist metaphysics, while others are decidedly dualist. Some claim ritual is the most efficacious means of religious attainment, while others assert that knowledge is more important".

In the pre-modern chemistry of Paracelsus, a clyssus, or clissus, was one of the effects, or productions of that art; consisting of the most efficacious principles of any body, extracted, purified, and then remixed. Or, a clyssus is when the several constituents of a body are prepared and purified separately, and then combined again. Thus, the five principles, reassembled into one body, by long digestion, make a clyssus. So, clyssus of antimony is produced by distillation from antimony, nitre, and sulfur mixed together.

In the last couple of decades, there has been a growing movement to integrate the various therapeutic approaches, especially with an increased understanding of cultural, gender, spiritual, and sexual- orientation issues. Clinical psychologists are beginning to look at the various strengths and weaknesses of each orientation while also working with related fields, such as neuroscience, behavioral genetics, evolutionary biology, and psychopharmacology. The result is a growing practice of eclecticism, with psychologists learning various systems and the most efficacious methods of therapy with the intent to provide the best solution for any given problem.

In November 2001, Genzyme chief executive Henri Termeer organised a systematic comparison of the various potential drugs in a mouse model of Pompe disease. It was found that the Duke enzyme was the most efficacious, followed by Myozyme. However, due to easier manufacture of Myozyme, work on the other products was discontinued. Funding for research in this field was in part provided by the Muscular Dystrophy Association and the Acid Maltase Deficiency Association in the US, and by the Association of Glycogen Storage Disorders in the UK, as well as the International Pompe Association.

For last several decades of the 20th century, all histological variants of NSCLC were generally treated identically. In the last decade, it has become apparent that different variants of malignant tumors generally exhibit diverse genetic, biological, and clinical properties, including response to treatment. As patients with uncommon lung tumor variants, including tumors composed of mixtures of histological subtypes, tend to be excluded from clinical trials, the most efficacious treatment regimen(s) for basaloid squamous cell carcinoma remain unknown. In general, these variants appear to be treated according to standard protocols in place for squamous cell carcinoma.

Before 1838, Davies Gilbert wrote that the flat country round it (St Dennis) is destroyed in the most efficacious manner, having been turned over and over again down to the solid rock, in what is termed streaming for tin. Between 1908 and 1916 steam powered suction and cutter dredges were used for the mining of alluvial tin on the moor. Drilling took place in 1908 and 1909 but the position of the boreholes and what they contained have been lost. Approximately 70 tons of tin concentrate was extracted and the dredges were later moved to Breney Common, Molinnis and Red Moor.

Ingruentium Malorum 12 He strongly encourages Catholic families to pray the rosary together. The rosary-praying family will become a place of sanctity, where the Holy Rosary will not only be the particular prayer but will also become a school of Christian discipline and Christian virtue. As a meditation on the Divine Mysteries of the Redemption the rosary teaches adults to live while fostering daily admiration of the examples of Jesus and Mary, and to draw from these examples comfort in adversity.Ingruentium Malorum, 14 > The custom of the family recitation of the Holy Rosary is a most efficacious > means.

In 2007 Sackeim and his colleagues published the results of a study which followed 250 patients who had received electroconvulsive therapy. The study found that the various techniques used when giving electroconvulsive therapy can have a direct impact on the adverse effects experienced by patients. Sackeim and colleagues later demonstrated that right unilateral electroconvulsive therapy with an ultra brief pulse appears to be the most efficacious, while remaining the least likely to cause adverse effects.'Effects of Pulse Width and Electrode Placement on the Efficacy and Cognitive Effects of Electroconvulsive Therapy', Sackeim et al, 'Brain Stimulation', 2008.

Concurrently, Thailand sought to add balance to its diplomacy by improving relations with Hanoi and Moscow. Diplomatic recognition was extended to Rumania, Outer Mongolia, and Czechoslovakia; a North Korean trade delegation visited Bangkok; and relations with China continued to warm.' During 1973-1976, a consensus developed within the Thai foreign policy elite, favorings decreased reliance upon the United States and return ing to a more traditional Thai stance of establishing cordial relations with as many contending powers as possible as the most efficacious means of protecting Thailand's sovereignty.Norman Peagam, "Thailand: Questioning the American Presence," Far Eastern Economic Review, 17 June 1974, p. 27.

Chapter 64, Practice in non-medical settings, in Rutter and Taylor (2002) In a review of existing meta-analyses and disorders on the four most frequent childhood and adolescent psychiatric disorders (anxiety disorder, depression, ADHD, conduct disorder), only for ADHD was the use of medication (stimulants) considered to be the most efficacious treatment option available. For the remaining three disorders, psychotherapy is recommended as the most effective treatment of choice. A combination of psychological and pharmacological treatments is an important option in ADHD and depressive disorders. Treatments for ADHD and anxiety disorders produce higher effect-sizes than do interventions for depressive and conduct disorders.

One of the most efficacious is the Turkana District Early Warning System in northern Kenya in which indicators include rainfall levels, market prices of cereals, status of livestock, rangeland conditions and trends, and enrollment on food-for-work projects. The system identifies three levels of crisis: alarm, alert and emergency, each of which is linked to a planned response to mitigate the crisis and try to prevent a worsening of the situation. International organizations responding to recent food crises created ad hoc measurements. In 2002, the World Food Programme created a number of "pre-famine indicators" for Ethiopia and combined it with measurements of nutrition levels to create recommendations.

Due to the geographic distribution of pneumococcal serotypes, additional research is needed to find the most efficacious vaccine for developing-world populations. In a previous study, the most common pneumococcal serotypes or groups from developed countries were found to be, in descending order, 14, 6, 19, 18, 9, 23, 7, 4, 1 and 15. In developing countries, the order was 6, 14, 8, 5, 1, 19, 9, 23, 18, 15 and 7. In order to further pneumococcal vaccine research and reduce childhood mortality, five countries and the Bill & Melinda Gates Foundation established a pilot Advance Market Commitment for pneumococcal vaccines worth US$1.5 billion.

It advises mortification and self-denial as the most efficacious weapons in this struggle. It teaches man to establish God's kingdom in his soul by the practice of virtues according to the example of Jesus Christ. It finally leads him to union with Christ by exciting love for him as well as by pointing out the frailty of all creatures: "It is necessary to leave the beloved thing for the beloved, because Jesus wishes to be loved above all things" (Oportet dilectum propter dilectum relinquere, quia Jesus vult solus super omnia amari: II, xvii). The thoughts of the "Imitation" are thrown into epigrams so simple that they are within the mental grasp of all.

Hyperbaric oxygen therapy increases oxygen transport via dissolved oxygen in serum, and is most efficacious where the haemoglobin is compromised (e.g. carbon monoxide poisoning) or where the extra oxygen in solution can diffuse through tissues past embolisms that are blocking the blood supply as in decompression illness. Hyperbaric chambers capable of admitting more than one patient (multiplace) and an inside attendant have advantages for the treatment of decompression sickness (DCS) if the patient requires other treatment for serious complications or injury while in the chamber, but in most cases monoplace chambers can be successfully used for treating decompression sickness. Rigid chambers are capable of greater depth of recompression than soft chambers that are unsuitable for treating DCS.

In Yasht 3.8, 11 and 15, the airyaman ishya is described as the weapon with which to put the daeva Taromaiti ("heresy") to flight.. Like the ahuna vairya invocation (the first of the four great formulas), the airyaman ishya is "the most excellent, the most mighty, the most efficacious, the most smiting, the most victorious, the most healing, the greatest" of the formulas. (Yasht 1.1-1.3, 3.5-3.6 and 11.3.) Also like the ahuna vairya, the airyaman ishya has the power to elicit good thoughts, words and deeds, and so further asha and weaken the druj. (Visperad 24.0-2). Since its incantation was considered the most effective form of healing (Yasht 3.6), the airyaman ishya was accorded special status in the religion.

V. lentus has been isolated from lesions found on the mantle and arms of the common octopus (Octopus vulgaris), where it forms rounded, hard lumps, and in more severe cases, loss of skin and exposure of the muscles beneath. Experimental introduction of the bacteria to healthy octopuses resulted in the formation of lesions, colonisation of the internal organs, and eventually death. The related species Vibrio harveyi is pathogenic to Gorgonian corals, oysters, prawns, lobsters, the common snook, barramundi, turbot, milkfish, and seahorses. In a research study in which over 200 bacterial isolates were tested in European sea bass (Dicentrarchus labrax) larvae as potential probiotics, V. lentus was the most efficacious, being harmless to the fish larvae and giving protection against vibriosis caused by V. harveyi.

The Bosporus (red), the Dardanelles (yellow), and the Sea of Marmara in between, are known collectively as the "Turkish Straits". Modern borders are shown. This article called for an alternative to Ottoman military support per the terms of the treaty; rather than sending troops and arms in support of their Russian allies, the Ottomans would close the Dardanelles to all foreign warships at Russia's command. Below is the full text of the secret article: > “In virtue of one of the clauses of Article I of the Patent Treaty of > Defensive Alliance concluded between the Imperial Court of Russia and the > Sublime Porte, the two High Contracting Parties, are bound to afford to each > other, mutually substantial aid, and the most efficacious assistance, for > the safety of their respective dominions.

However, they were defeated by Czechoslovakia, 0–3, with Renáta Tomanová and Martina Navratilova overcoming them in only 36 games. Melville returned to the team in 1976 under her married name of Reid and she, alongside Goolagong (who reached the World No. 1 ranking for two weeks) and Fromholtz sent Australia to the final for the fourth consecutive time. They were still unable to claim their eighth title, nevertheless; on this occasion they were defeated by their old rivals from the United States, World No. 5 and successful doubles player Rosemary Casals and Moffitt, then known as Billie Jean King, who had become one of the most efficacious players of all time. After this tournament Goolagong left the Fed Cup team for a while, leaving it in the hands of Fromholtz, Reid and Top 10 player Wendy Turnbull.

War was declared to be the end product of the competition of capitalist nations in the world market, bolstered by "national prejudices systematically cultivated in the interests of the ruling classes". The resolution called for the replacement of standing armies by the democratic organization of "the armed people" — which, it was claimed, "would prove an effective means for making aggressive wars impossible". In the event of imminent war, the working class was mildly beseeched to "do all they can to prevent the breaking out of this war, using for the purpose the means which appear to them most efficacious". Should war nevertheless follow, the socialists were "bound to intervene for its being brought to a speedy end" and to make use of the economic and political crises created by the war "to hasten the breakdown of the predominance of the capitalist class".

But there was one source of embarrassment greater than all the rest. One strong motive which had impelled him to engage in this enterprise was his anxious desire to establish more friendly relations between Britain and France, and to dispel those feelings of mutual jealousy and alarm which were so frequently breaking forth and jeopardizing peace between the two countries. This was the most powerful argument with which he had plied the emperor and the members of the French government, and which he had found most efficacious with them. But while he was in the midst of the negotiations, Lord Palmerston brought forward in the House of Commons a measure for fortifying the naval arsenals of Britain, which he introduced in a warlike speech pointedly directed against France, as the source of danger of invasion and attack, against which it was necessary to guard.

Hope and optimism serve as powerful catalysts for action. Research contends that prognostic framing—which offers tangible solutions, strategies, targets, and tactics—coupled with motivational framing is most efficacious in moving people to act. Especially as it relates to climate change, the power of positive psychology is made evident when applied by activists and others generating interventions. The four main tenets of motivation as elucidated by Positive Psychology are agency, compassion, resilience, and purpose. When applied to climate action, the 4th edition textbook Psychology for Sustainability, further expands upon these tenets as they relate to sustainability and as catalysts of action: # Agency: Choosing, planning, and executing situation-relevant behavior # Compassion: Noticing, feeling, and responding to others’ suffering arising from a sense of connectedness # Purpose: Striving toward meaningful activity # Resilience: Recovering from, coping with, or developing new strategies for resisting adversity Hope is a critical component in augmenting a sense of purpose and agency, while enhancing resilience.

Among other ingredients entering into some of these formulae were the excrements of human beings, dogs, mice, geese, and other animals, calculi, human skull, and moss growing on it, blind puppies, earthworms, etc. Although other editions of the London Pharmacopoeia were issued in 1621, 1632, 1639, and 1677, it was not until the edition of 1721, published under the auspices of Sir Hans Sloane, that any important alterations were made. In this issue many of the remedies previously in use were omitted, although a good number were still retained, such as dogs’ excrement, earthworms, and moss from the human skull; the botanical names of herbal remedies were for the first time added to the official ones; the simple distilled waters were ordered of a uniform strength; sweetened spirits, cordials and ratafias were omitted as well as several compounds no longer used in London, although still in vogue elsewhere. A great improvement was effected in the edition published in 1746, in which only those preparations were retained which had received the approval of the majority of the pharmacopoeia committee; to these was added a list of those drugs only which were supposed to be the most efficacious.