" – Kauffmann Pulp Fiction "[W]hat's most bothersome about Pulp Fiction is its success.
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For adults, there's little evidence that decongestants help with congestion, one of the most bothersome cold symptoms.
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The results aren't always pretty, but it handles some of the most bothersome first steps of video editing.
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The majority of people ranked "uncomfortable beds and towels" as most bothersome, above small bathrooms or mismatched décor.
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At the outset of the study, all the participants rated the severity of their most bothersome symptom at about 2.5.
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Blockchain, the decentralized record-keeping system, could help tackle some of Facebook's most bothersome problems, like identity verification or advertising sales.
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The lower dose had 20.7% of participants feeling pain-free after two hours and 34.1% relieved of the most bothersome symptoms.
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The sounds are designed to mask particular frequencies most bothersome and detrimental to sleep rather than every loud noise you might encounter.
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But most bothersome were the moments in which BET revealed that it still hasn't committed to intersectionality as a framework for Black liberation.
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The most bothersome thing for me is getting emails all the time from women all over the world, saying: They say I have depression.
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The most bothersome feature of the game is the lazy way they chose to add inventory and health menus to float in space in front of you.
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For adults and older children, whooping cough can often be treated at home with a course of antibiotics, with the severe hacking cough being the most bothersome symptom.
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The most bothersome source of interference is unintentional radio noise from spacecraft electronics, which could be avoided by asking moon-bound missions to include strong electromagnetic shielding for their spacecraft.
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To see what symptoms patients find most bothersome, van Driel and colleagues asked 10 customers seeking over-the-counter treatments at a community pharmacy in Belgium what concerned them the most.
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About 39 percent in the 50mg group also reported the absence of their most bothersome symptom (MBS), such as nausea or sensitivity to light or sound, compared with 27.4 percent for placebo.
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They prevent unscrupulous doctors from convincing their most bothersome patients to ask for assisted suicide and they keep sick people from the devastating feeling that they should kill themselves to stop being a burden.
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The research team found at the end of the trial that women in all of the groups had average reductions of 1.2 to 1.4 points, or about 50 percent, in the severity of their most bothersome symptom.
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She also receives visitors, the most bothersome being Ginny Smythson-Balby, who possesses "attention-seeking breasts" and claims to be a local reporter, though her home is in faraway Notting Hill and she doesn't ask any good questions.
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Corporate and political advertising are being "mushed together" as a single topic of discussion, but it is political micro-targeting that is most bothersome to consumers, says Karen Kornbluh, senior fellow for digital policy at the Council on Foreign Relations.
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The drug, ubrogepant, showed greater rates of pain and symptom relief from migraine compared to a placebo, with more than 20% of participants given the drug reporting to be pain-free within two hours and more than 34% relieved of the most bothersome symptoms linked to migraine, which include light and noise sensitivity.
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In a study published last month, the drug showed greater rates of pain and symptom relief from migraine compared to a placebo, with more than 19% of participants given the drug reporting to be pain-free within two hours and nearly 40% relieved of the most bothersome symptoms linked to migraine, which include light and noise sensitivity.
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Science fiction and fantasy writer Roland J. Green wrote in a review of Yvgenie in the Chicago Sun-Times that he was impressed with Cherryh's "characterization and knowledge of folklore", and described the whole Russian series as her "most significant work of fantasy". A reviewer in Kirkus Reviews was less enthusiastic about Yvgenie, saying that the "most bothersome aspect" of this story is its "sourceless, effortless magic", and did not expect the book to attract too many devotees, except perhaps young readers who may be drawn to Ilyana's predicament.
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Topline results from the SPARTAN trial showed that the drug induced met its primary and secondary endpoints in the trial. The primary result showed a statistically significant improvement in pain relief relative to placebo 2 hours after the first dose. The secondary result showed a statistically significantly greater percentage of subjects were free of their most bothersome symptom (MBS) compared with placebo at two hours following the first dose. The FDA approved lasmiditan primarily based on data from two clinical trials, Trial 1 (# NCT02439320) and Trial 2 (#NCT02605174) of 4439 subjects with migraine headaches with or without aura.
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A 2004 meta-analysis comprising three randomized placebo-controlled studies with a total of 173 patients suggested that iberogast was more effective than placebo in relieving "the most bothersome gastrointestinal symptom" of functional dyspepsia as identified by each patient. Additionally, a single reference-controlled study was discussed, comparing iberogast to the prokinetic cisapride in the treatment of "'functional dyspepsia of the dysmotility type'" and finding no significant differences in efficacy or tolerability. This paper noted that, while iberogast seems to consistently provide symptomatic relief to patients, its efficacy is more evident "with associated symptoms of gastro-oesophageal reflux or predominance of epigastric pain." It suggests a synergy of therapeutic mechanisms provided by the complex interactions between the GI tract and each individual component of iberogast.
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The effectiveness of ubrogepant for the acute treatment of migraine was demonstrated in two randomized, double-blind, placebo-controlled trials. In these studies, 1,439 adult patients with a history of migraine, with and without aura, received the approved doses of ubrogepant to treat an ongoing migraine. In both studies, the percentages of patients achieving pain freedom two hours after treatment (defined as a reduction in headache severity from moderate or severe pain to no pain) and whose most bothersome migraine symptom (nausea, light sensitivity or sound sensitivity) stopped two hours after treatment were significantly greater among patients receiving ubrogepant (19–21% depending on the dose) compared to those receiving placebo (12%). Patients were allowed to take their usual acute treatment of migraine at least two hours after taking ubrogepant.
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