Human smugglers tend to use more rudimentary tunnels, he said.
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But keeping tabs on patients is more rudimentary in the NHS.
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But Sailor says this tech is much more rudimentary than IC Realtime's.
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The men—Tom and Megan's husband Scott (Luke Evans)—feel even more rudimentary.
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But reduced to 10 men apiece, the teams resorted to more rudimentary maneuvers.
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The new policy doesn&apost cover more rudimentary forms of doctored videos either.
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That process could expose problems in the research that a more rudimentary read can't catch.
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Most RISC-V based processors serve more rudimentary functions, such as powering simple internet-of-things devices.
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Many scholars and thinkers have expanded on Butler's theory or challenged other, more rudimentary "performance"-based theories.
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Hammy's pleasures are more rudimentary: a cold beer and cigarettes, milk, and a new woman every night.
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Coming to these campgrounds sight unseen requires a degree of adaptability, as some are more rudimentary than others.
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"Some countries have fewer resources and more rudimentary systems, which can result in delays and missed outbreaks," she said.
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These games are very different from more rudimentary games like Pong and Space Invaders that older men grew up playing.
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The attack in Barcelona, capital of the Spanish region of Catalonia, was therefore "more rudimentary than they originally planned," Trapero said.
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Some fear that if neither of these strategies works, high-earners may take a more rudimentary route to tax avoidance: relocation.
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"The three-generation model only has SU(3) × U(1), so it's more rudimentary," Furey told me, pen poised at a whiteboard.
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This app was more rudimentary: It essentially scrolled through my timeline and clicked on the "delete" button for each of my posts for me.
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The apparently accidental explosion at the house forced the conspirators to scale down their plans and to hurriedly carry out more "rudimentary" attacks, police say.
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And yet this act, whatever its particulars, represents the culmination of long-building trends, in which terror tactics become more rudimentary and the targets more random.
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It then invites users to follow a link to verify their identity, and this is the part that distinguishes it from a more rudimentary phishing attempt.
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You can also trigger the dispensing of a treat, of course, and this is where the Bites departs from a more rudimentary two-way connected home camera.
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It's all a bit more rudimentary than it is on iOS: There's no option to view app use by category, or to set limits by category rather than by individual apps.
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While the system has been very useful for Israel against more rudimentary Hamas- and Hezbollah-launched projectiles, it would be less so against weapons like hypersonic missiles, which can maneuver midflight.
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If you're using OneDrive and Office on the web, you can access a more rudimentary version of this feature by selecting File, Info, and Previous Versions with the file open on screen.
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The tech was even more rudimentary for John Jacobs as he drove in a minivan from door to door in a quintessential Polish neighborhood, West Alilis, famous for its Christmas season decorations.
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The scene was enough to take Sisley back to 1966, when the women's team she coached at Oregon featured more rudimentary basketball: half-court games; pinnies for uniforms; and once-a-week practices.
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You might recall that WhatsApp actually announced a version of this feature back in April that was more rudimentary: you could select Nobody, Everybody or Contacts (but not specific contacts) to add you to Groups.
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I think with the automation move and the use of artificial intelligence perhaps taking away some of the more rudimentary roles, there's a big obligation to make sure we're retraining our associates for the future.
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Facebook's partner Samsung is already selling a more rudimentary $99 headset, the Gear VR. Apple has filed dozens of virtual reality-related patents in the past, including one in 2008 for a head-mounted display apparatus.
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Considering he finishes each sketch in about 20 seconds, most caffeine-starved customers get a more rudimentary image like a happy sun with some inspirational words alongside it or Snoopy stretched out atop the Starbucks' siren.
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Users who remember interacting with those more rudimentary video games will enjoy discovering commands like "take" to add any object to your "inventory" (I picked up "Pittsburgh" and the "glass cube" from the American Museum of Natural History).
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This had forced the conspirators to scale down their plans and to hurriedly carry out more "rudimentary" attacks in Barcelona and the resort of Cambrils, where a group of men drove a car at pedestrians and police before being shot dead.
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Instead, U.S. forces took advantage of the hours of early warning provided by U.S. intelligence and were able to take more rudimentary defensive measures before missiles fired from at least three locations inside of Iran hit their targets in Iraq.
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That Black Wax Ms. West used waterproof fabrics popular with mountain climbers to line many of the more rudimentary pieces she built, including moccasins and a type of early leg warmer that involved wrapping shins with fur held in place with strips of leather.
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This problem has been one that numerous companies in the AR enterprise space have been tackling, though Remote Assist is still more rudimentary than products from startups like Scope AR, which allow users to integrate CAD files that can be mapped directly onto machinery.
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But when Kim hears Libya he thinks of the assassination of its longtime dictator, Moammar Gadhafi, after a NATO-led air operation in 2011 that may not have happened had he not previously given away a nuclear program that was far more rudimentary than North Korea's.
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"[Financial automation] helps to simplify some of the more rudimentary financial tasks that we all have to do," says Jacquette M. Timmons, a financial behaviorist, author of "Financial Intimacy: How to Create a Healthy Relationship with Your Money and Your Mate" and president and CEO of Sterling Investment Management Inc.
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While thoroughly modern systems like Tesla's Autopilot, Cadillac's Super Cruise and even Ford's own Co-Pilot 4.53 will automatically hold you in the center of the lane and provide steering input around bends, the more rudimentary Navigator makes do with an older system that merely bounces you back if you clip a lane marking.
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A black banya is more rudimentary than a white banya. Traditional Northern Russia banya in Mandrogy open air museum.
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The vast waters are dotted with sailing vessels. Where the water spills upon the ground below, grass and a more rudimentary civilization spring up.
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Police chief Josep Lluís Trapero believed terrorists were in the process of manipulating the gas canisters when they exploded, after which they decided to continue their plans by conducting more rudimentary vehicle ramming attacks.
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Many of these challenges are exacerbated when the records are still in the custody of the generating body or in private hands, where owners or custodians may be unwilling to provide access to external enquirers, and where finding aids may be even more rudimentary or non-existent.
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The Sonjo also maintain terraced village sites, albeit of considerably more rudimentary form than what is found at Engaruka. New studies have also revealed new information about the Middle Stone Age and Pastoral Neolithic occupational histories of the area.Seitsonen, Oula. 2005. ‘Stone Age observations in the Engaruka area’, in Nyame Akuma 63, 27-32.
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Troubadours performed their own songs. Jongleurs (performers) and cantaires (singers) also performed troubadours' songs. They could work from chansonniers, many of which have survived, or possibly from more rudimentary (and temporary) songbooks, none of which have survived, if they even existed. Some troubadours, like Arnaut de Maruelh, had their own jongleurs who were dedicated to singing their patron's work.
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They refer to it as Kitemi or Gitemi. The Sonjo are known for their use of irrigation systems in agriculture. They have consequently been linked by some historians with the Engaruka complex, situated some 60 miles to the southeast. The Sonjo also maintain terraced village sites, albeit of considerably more rudimentary form than what is found at Engaruka.
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The national medical insurance scheme covers 90% of the entire population. The Algerian government decided to invest in government run expansive health care centres and clinics instead of investing in expensive hospitals. The health care facilities and medical equipment varies in size depending on the size of local population. Remote areas tend to get more rudimentary medical services.
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Calcidius' commentary on Plato's Timaeus praises Alcmaeon (as well as Callisthenes and Herophilus), about their work on the nature of the eye. He mentions that Alcmaeon excised an animal eye to study the optic nerve. However, there is no evidence that Alcmaeon himself dissected the eye or the skull. Based on this observation, and more rudimentary, Alcmaeon described the senses, except for the touch sense.
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Corinna Thierolf, "Robert Rauschenberg: Borealis 1988-92" (Galerie Thaddaeus Ropac: 2019). Urban Bourbons (1988-1996), Phantoms (1991), and Night Shades (1991). In addition, throughout the 1990s, Rauschenberg continued to utilize new materials while still working with more rudimentary techniques. As part of his engagement with the latest technological innovations, in his late painting series he transferred digital inkjet photographic images to a variety of painting supports.
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Deontological judgements linked to emotional and intuitive responses were developed by human beings as they were confronted with personal and close interactions with others. In the past century, our social organizations were altered and this type of interactions have become much less frequent. Therefore, we should rather rely on more sophisticated consequently judgements that fit better in our modern times, than deontological judgements that were useful for more rudimentary interactions.
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Calkins, calls for a more deeper analysis of the history than presented in this volume. Despite of the apparent image of "the official Pakistani point of view" intended to be used as textbook for undergraduate students, the volume should have been able to offer more for those who desire more rudimentary knowledge of sultanate period. He praises the particular aspect of the book as "historigraphical rather than historical".
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Multicylinder flathead engines were used for cars such as the Ford Model T, the Ford flathead V8 engine and the Ford Sidevalve engine. Cadillac produced V-16 flathead engines for their Series 90 luxury cars from 1938–1940. After WWII, flathead designs began to be superseded by OHV (overhead valve) designs. Flatheads were no longer common in cars, but they continued in more rudimentary vehicles such as off-road military Jeeps.
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A far more rudimentary form of double fertilization occurs in the sexual reproduction of an order of gymnosperms commonly known as Gnetales. Specifically, this event has been documented in both Ephedra and Gnetum, a subset of Gnetophytes. In Ephedra nevadensis, a single binucleate sperm cell is deposited into the egg cell. Following the initial fertilization event, the second sperm nucleus is diverted to fertilize an additional egg nucleus found in the egg cytoplasm.
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Head of a woman discovered at Uruk, the 'Mask of Warka'. The Uruk period saw a notable renewal, which accompanied substantial changes in the symbolic sphere. This is visible primarily in the artistic media: the forms of pottery became more rudimentary, after the development of the potter's wheel, which allowed mass- production without a focus on decorative elements. Painted pottery is less common than in previous periods, with no decoration or just incisions or pellets.
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A more rudimentary (or in some cases, supplementary) manual element to structured queue management involves the addition of a member of human staff to deliver a system, monitoring structured queue lengths in order to guide people in a queue or to make adjustments to speed up service (e.g. fetching more cashiers). Such systems are used in UK supermarkets, for example, where the addition of a 'host' role or Customer Service Manager may occur.
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Within a full gamelan, it stands out somewhat because of the high speed of playing, and contrasting timbre because of its materials and more because it has a wider melodic range than the other instruments. In Javanese gamelan, the gambang plays cengkok like the other elaborating instruments. However, the repertoire of cengkok for the gambang is more rudimentary than for other instruments (for instance, the gendér), and a great deal of variation is accepted.
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The breezeway is interrupted by an early concrete storage space around which a timber stair to the lower floor winds. The first floor has several elements of high quality timber joinery including architraves, window framing and skirtings. The lower floor is a more rudimentary space, with lower ceilings, very little decorative treatment and plain concrete dividing walls. The house adjoins a more recent building via a walkway from an existing opening on the first floor.
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Within a year of prohibition, the number of murders and gang robberies decreased by 20%. The number of riots fell by 13% and traffic accidents were reduced by 10%. For the economy, spending per household rose: increase in sales of milk by 10%, cheese by 200%, two-wheeled vehicles by 30%, and electrical appliances by 50%. In villages, brick houses are gradually taking the place of more rudimentary cottages since state Prohibition came into effect.
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Not all languages using clicks as phonemes are considered Khoisan. Most others are neighboring Bantu languages in southern Africa: the Nguni languages (Xhosa, Zulu, Swazi, Phuthi, and Northern Ndebele); Sotho; Yeyi in Botswana; and Mbukushu, Kwangali, and Gciriku in the Caprivi Strip. Clicks are spreading to a few additional neighboring languages. Of these languages, Xhosa, Zulu, Ndebele and Yeyi have intricate systems of click consonants; the others, despite the click in the name Gciriku, more rudimentary ones.
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The phone features T9 text input (optional), with functions allowing the user to expand the default dictionary with their own terms. This only works with languages supported by the phone, wherein the display languages for the North American market are English, French, and Spanish. More rudimentary features in the phone are alarms (including alarm during power off), calculator, calendar, "To do" list, voice memo, currency converter and world time. The device contains software or functionality from RSA Security.
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The rooms are generally larger, with better fittings on the second floor, and more rudimentary accommodation provided on the first. A large second floor room on the principal corner of the building, accessing the small balcony in the tower, features an ebonised and marbellised timber fireplace, with iron register grate intact. Bathrooms throughout the interior have been modernised. Interior joinery throughout the first and second floor remains intact and of high quality, although now heavily painted.
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Shared file access should not be confused with file transfer using the file transfer protocol (FTP), or the Bluetooth IRDA OBject EXchange (OBEX) protocol. Shared access involves automatic synchronization of folder information whenever a folder is changed on the server, and may provide server side file searching, while file transfer is a more rudimentary service. Share Files across Cloud Storage. Shared file access is normally considered as a local area network (LAN) service, while FTP is an Internet service.
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From 1875 to 1965, a more rudimentary structure existed in the same location. Built by the Belfast Central Railway as part of its line which linked the Great Northern Railway and the Belfast and County Down Railway, it was a single track eight-span wooden bridge. Heavier locomotives were banned from crossing it, and by the time it was closed by the Ulster Transport Authority in 1965, it had earned the nickname, The Lagan Shaky Bridge. It was subsequently demolished shortly after closure.
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A marímbula, the "bass" instrument used by changüí ensembles. Some groups used the more rudimentary jug known as botija or botijuela. Although the history of Cuban music dates back to the 16th century, the son is a relatively recent musical invention whose precursors emerged in the mid-to-late 19th century. Historically, most musicologists have supported the hypothesis that the direct ancestors (or earliest forms) of the son appeared in Cuba's Oriente Province, particularly in mountainous regions such as Sierra Maestra.
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Remote areas tend to get more rudimentary medical services. The Algerian government had a 4-year plan from 2010–14, which was expected to spend €5.7bn in health care which a majority of the fund directed in the establishment of over 1,500 health care facilities all over Algeria. By 2015, the Algerian government had allocated €4.85bn to build 10 hospital and renovate old ones. The Algerian government is investing in human resources by creating 58,000 jobs in nursing, doctors and health care assistants.
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Tass Times had different features and graphics depending on which system it was developed for. This was a common practice for games of its era due to the disparate abilities of the systems of that era. For example, the higher-end system (Amiga, Atari ST and Apple IIGS) versions had 16-32 color graphics and wavetable sound, while the lower-end (Apple II, PC) versions had more rudimentary graphics. Likewise, the higher-end systems supported sound, while some of the lower-end ports had no sound capability.
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There are two distinct modes of live- preview, with only a few manufacturers offering both in their digital cameras. The first is a more rudimentary type of live preview that displays the overall framing on an electronic display and allows a preview of what the camera's sensor will detect before the photograph is taken. This can be particularly helpful when the lighting conditions are too dark for an optical viewfinder. This type of live preview is the autogain/framing live view type (or framing priority display).
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The elaborate summoning of the Sicilian Muse Thalia celebrates antiquity and the pastoral genre. Furthermore, this introduction involving a Grecian muse emphasizes ingenio itself over that of a more rudimentary imitation delineated by regulations and set expectations. Imitatio (the reverential imitation of the art of the ancients) was prevalent in Renaissance poetry as seen in the verse of the highly influential Spanish poet Garcilaso de la Vega who in turn borrowed heavily from the Italian Dolce Stil Novo poets, such as Petrarch, who revolutionized the poetry of the 14th and 15th centuries.
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The huts for European patients were small single roomed, timber buildings, while the huts for the non-European patients were more rudimentary structures of bush timber clad with tea tree bark. The durability of the bark cladding was short-lived, and in 1909 the huts were reclad with corrugated galvanised iron. However, the Queensland Government eventually abandoned the idea of housing non-European patients on Peel Island. By January 1939 several suspected Hansen's disease cases from Thursday Island and Cooktown had been sent to Fantome Island, while further cases were present on Palm Island.
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A satisfactory characterisation of this part of the dialogue has eluded scholars since antiquity. Many thinkers have tried, among them Cornford, Russell, Ryle, and Owen; but few would accept without hesitation any of their characterisations as having got to the heart of the matter. Recent interpretations of the second part have been provided by Miller (1986), Meinwald (1991), Sayre (1996), Allen (1997), Turnbull (1998), Scolnicov (2003), and Rickless (2007). It is difficult to offer even a preliminary characterisation, since commentators disagree even on some of the more rudimentary features of any interpretation.
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This mystical concept of God as the wellspring of being is seen in the works and ideas of Aquinas and can be seen as a simplistic rendering of apotheosis and a more rudimentary form of the doctrine of divine simplicity. She describes God in her work, 'the Dialogues', as a "sea, in which we are the fish", the point being that the relationship between God and man should not be seen as man contending against the Divine and vice versa, but as God being the endless being that supports all things.
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The Great Harry, launched at Woolwich in 1514. Woolwich Dockyard was founded by King Henry VIII in 1512 to build his flagship Henri Grâce à Dieu (Great Harry), the largest ship of its day.Woolwich, Encyclopædia Britannica Online Library Edition, 2010 The ship was built in Old Woolwich, which is where the dockyard was initially established: past Bell Water Gate, east of the area later known as Woolwich Dockyard. The site consisted of one or more rudimentary dry docks, a long storehouse (for canvas, rigging and other materials) and a small assortment of other buildings.
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Female P-cell dominance is tied to foraging for plants, a task requiring discrimination between colors and memory of form. Color is particularly important in foraging, as discrimination between colors aids in identifying a ripe piece of fruit from the greenery around it. As it were, the "green-red opponent system" is thought to be X-chromosome linked and phylogenetically more recent, in contrast with the more rudimentary "yellow-blue" system present to the same degree in both sexes (Alexander, 2003). According to the theory, this adaptation has persisted throughout human evolution, and may contribute to contemporary sexual- dimorphism in skill and preference.
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The Maya, along with several other cultures in Mesoamerica, constructed concertina-style books written on Amate paper. Nearly all Mayan texts were destroyed by the Spanish during colonization on cultural and religious grounds. One of the few surviving examples is the Dresden Codex. Although only the Maya have been shown to have a writing system capable of conveying any concept that can be conveyed via speech (at about the same level as the modern Japanese writing system), other Mesoamerican cultures had more rudimentary ideographical writing systems which were contained in similar concertina-style books, one such example being the Aztec codices.
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A slog is a powerful pull shot played over mid-wicket, usually, hit in the air in an attempt to score a six. A shot would be referred to as a slog when it is typically played at a delivery that would not ordinarily be pulled. A slog can also be described as hitting the ball to "cow corner". This phrase is designed to imply that the batting player is unsophisticated in their strokeplay and technique by suggesting they would be more at home playing on more rudimentary cricket fields in which there may be cows grazing along the boundary edge.
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They have simply made use of the clichés which require (a) that one man go berserk from the strain, (b) that one man try to escape at the expense of the others, and (c) that the tight- lipped hero has a heartbreaking story locked in his memory somewhere. From time to time Mr. Nolan dose succeed in creating a credible hero, but for the most part the characters are hackneyed in writing and performance. As an action film of the more rudimentary kind, 'Manila Calling' is continuously noisy. But considering" the subject and the times, that hardly seems enough".
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For example, the WT framework was adopted as the basic presentation framework in the parallel algorithms books (for the PRAM model) and , as well as in the class notes . explains the simple connection between the WT framework and the more rudimentary ICE abstraction noted above. The XMT paradigm can be programmed using XMTC, a parallel multi-threaded programming language which is a small extension of the programming language C. The XMT paradigm include a programmer’s workflow that starts with casting an algorithm in the WT framework and proceeds to programming it in XMTC. The XMT multi-core computer systems provides run-time load-balancing of multi-threaded programs incorporating several patents.
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Little Prelude in C major, BWV 933 played on a harpsichord by Gérard Janot The C major prelude consists of two brief sections, repeated as a pair, followed by a variation on each section, again repeated as a pair.BWV 933 in The Mutopia Project: Praeludium Nr. 1, by J. S. Bach (1685–1750) The first segment demands complete independence of the right and left hands, with the left hand providing a busy accompaniment. The bass material becomes more rudimentary in the second segment, as the treble adopts f of this prelude makes minimal changes to the basic material, mainly brightening it by lifting the slightly altered melody into a higher register.
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Modern terminology would categorize the objects included as belonging to natural history (sometimes faked), geology, ethnography, archaeology, religious or historical relics, works of art (including cabinet paintings), and antiquities. The classic cabinet of curiosities emerged in the sixteenth century, although more rudimentary collections had existed earlier. In addition to the most famous and best documented cabinets of rulers and aristocrats, members of the merchant class and early practitioners of science in Europe formed collections that were precursors to museums. Cabinets of curiosities served not only as collections to reflect the particular curiosities of their curators but as social devices to establish and uphold rank in society.
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Dedicated word processors and WP software for general-purpose computers that rose in popularity in the late 1970s and 1980s would use features such as microspacing (usually by 1/120 of an inch horizontally and, possibly, 1/48 of an inch vertically) to implement subscripts, proportional spacing, underlining, and so on. The more rudimentary software packages would implement bold text by overtyping the character in exactly the same spot (for example, using the backspace control code), but better software would print the letter in 3 slightly different positions. Software did exist to (slowly) produce pie charts on such printers (and on some daisywheels the dot was reinforced with metal to cope with extra wear).
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Previously, in the 16th century, Spanish theologian Francisco de Vitoria postulated the idea of freedom of the seas in a more rudimentary fashion under the principles of jus gentium. During World War II, nations started to expand and claim many resources and water territories all over their surrounding coasts. There were four international treaties meticulously drafted in the late 1950s and onto the 1970s, but the issues were not resolved between nations until 1982 when the United Nations Convention on the Law of the Sea was introduced. UNCLOS is a Law of the Sea treaty: an agreement of rights and responsibilities of nations and their use of the world’s ocean with guidelines of trade, environment, and the management of marine and open seas resources.
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Such huts exist at many different heights, including in the high mountains themselves – in extremely remote areas, more rudimentary shelters may exist. The mountain huts are of varying size and quality, but each is typically centred on a communal dining room and have dormitories equipped with mattresses, blankets or duvets, and pillows; guests are expected to bring and use their own sleeping bag liners. The facilities are usually rudimentary, but, given their locations, huts offer vital shelter, make routes more widely accessible (by allowing journeys to be broken and reducing the weight of equipment needing to be carried), and offer good value. In Europe, all huts are staffed during the summer (mid-June to mid-September) and some are staffed in the spring (mid-March to mid-May).
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On the southern wall of the room, adjacent to where a raised platform indicates the chancel area, are four fine stained glass window panels, in trefoil arched openings, depicting the four Evangelists and from the Royal Bavarian Art Institute for Stained Glass. The eastern wall of the front section of the cheap features large pointed arched window openings, with grisaille stained glass panels. The more rudimentary rear section of the chapel has a timber fireplace, a walk through sash window and French door with transom light opening to the adjacent verandah. To the north of the chapel, and separated by a stair hall, is the 1914 addition, which comprises large rooms with Wunderlich pressed metal ceilings featuring fleur-de-lis and Greek cross motifs and rendered walls with dado and picture rails impressed in the plaster.
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Until 1971, most editors tended to consider All Religions are One as later than There is No Natural Religion. For example, in his 1905 book The poetical works of William Blake; a new and verbatim text from the manuscript engraved and letterpress originals, John Sampson places No Natural Religion prior to All Religions in his 'Appendix to the Prophetic Books'. However, in 1971, Geoffrey Keynes argued that All Religions are One was the earlier of the two, based on what he saw as its "greater technical imperfection."Erdman (1982: 789) In his 1978 book, The Complete Graphic Works of William Blake, David Bindman initially disagreed with Keynes, arguing that the imperfections in All Religions are not because of an earlier date of composition, but because of the increased complexity of the plates, with such complexity demonstrating Blake growing in confidence from the more rudimentary plates for No Natural Religion.
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Grotius, by claiming 'free seas' (Freedom of the seas), provided suitable ideological justification for the Dutch breaking up of various trade monopolies through its formidable naval power (and then establishing its own monopoly). England, competing fiercely with the Dutch for domination of world trade, opposed this idea and claimed in John Selden's Mare clausum (The Closed Sea), "That the Dominion of the British Sea, or That Which Incompasseth the Isle of Great Britain, is, and Ever Hath Been, a Part or Appendant of the Empire of that Island." It is generally assumed that Grotius first propounded the principle of freedom of the seas, although all countries in the Indian Ocean and other Asian seas accepted the right of unobstructed navigation long before Grotius wrote his De Jure Praedae (On the Law of Spoils) in the year of 1604. Additionally, 16th century Spanish theologian Francisco de Vitoria had postulated the idea of freedom of the seas in a more rudimentary fashion under the principles of jus gentium.
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Luttwak (1976) 134–5 This view is too extreme, as all the evidence suggests that such forts, even the more rudimentary earlier type based on the design of marching-camps (ditch, earth rampart and wooden palisade), afforded a significant level of protection. The latter is exemplified by the siege of the legionary camp at Castra Vetera (Xanten) during the revolt of the Batavi in 69–70 AD. 5,000 legionaries succeeded in holding out for several months against vastly superior numbers of rebel Batavi and their allies under the renegade auxiliary officer Civilis, despite the latter disposing of c. 8,000 Roman-trained and equipped auxiliary troops and deploying Roman-style siege engines. (The Romans were eventually forced to surrender the fort by starvation).Tacitus Historiae IV.22, 23, 29, 30, 60 Nevertheless, later forts were undoubtedly built to much higher defensive specifications than their 2nd-century predecessors, including the following features: #Deeper (average: 3 m) and much wider (av.
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KcsA was the first potassium ion channel to be characterized using x-ray crystallography by Roderick MacKinnon and his colleagues in 1998. In the years leading up to this, research on the structure of K+ channels was centered on the use of small toxin binding to reveal the location of the pore and selectivity filter among channel residues. MacKinnon’s group theorized the tetrameric arrangement of the transmembrane segments, and even suggested presence of pore-forming “loops” in the filter region made of short segments of amino acids that interacted with K+ ions passing through the channel The discovery of strong sequence homology between KcsA and other channels in the Kv family, including the Shaker protein, attracted the attention of the scientific community especially as the K+ channel signature sequence began to appear in other prokaryotic genes. The simplicity of the two transmembrane helices in KcsA, as opposed to the six in many eukaryotic ion channels, also provided a method to understand the mechanisms of K+ channels conduction at a more rudimentary level, thereby providing even great impetus for the study of KcsA.
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