3 Sentences With "monozygous twins"

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The incidence of multiple births increases with the age of the mother but distinctly more so for dizygous rather than for monozygous twins and more so still for triplets.
Monochorionic twins are twins that share the same placenta. This occurs in 0.3% of all pregnancies, and in 75% of monozygotic (identical) twins, when the split takes place on or after the third day after fertilization. The remaining 25% of monozygous twins become dichorionic diamniotic. The condition may affect any type of multiple birth, resulting in monochorionic multiples.
Genetic alterations involving gains or loss of entire chromosomes predominantly occur during anaphase stage of cell division. But these are uncommon in somatic cells because they are usually selected against due to their deleterious consequences. Somatic variations during embryonic development can be represented by monozygous twins since they carry different copy number profiles and epigenetic marks that keep on increasing with age. Early research on somatic mutations in aging showed that deletions, inversion and translocations of genetic material are common in aging mice and aging genomes tend to contain visible chromosomal changes, mitotic recombination, whole gene deletions, intragenic deletions and point mutations.