How to use makes holes in in a sentence? Find typical usage patterns (collocations)/phrases/context for "makes holes in" and check conjugation/comparative form for "makes holes in". Mastering all the usages of "makes holes in" from sentence examples published by news publications.
Even so, Luke's enemies try pretty damn hard to hurt him, even if it only makes holes in his hoodie.
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Brooke realises TK still loves Sarah so she attempts to fall pregnant by him. She makes holes in condoms - but it backfires when Loren Fitzpatrick (Sophia Johnson), becomes pregnant instead. When Brooke becomes too needy, TK breaks up with her. She then strikes up a friendship with Gerald Tippett (Harry McNaughton).
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S is a holin, a small membrane protein that, at a time determined by the sequence of the protein, suddenly makes holes in the membrane. R is an endolysin, an enzyme that escapes through the S holes and cleaves the cell wall. Rz and Rz1 are membrane proteins that form a complex that somehow destroys the outer membrane, after the endolysin has degraded the cell wall. For wild-type lambda, lysis occurs at about 50 minutes after the start of infection and releases around 100 virions.
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Fanning levels also increase when the water is poorly oxygenated. Towards the end of the egg development phase, the male often makes holes in the roof and near the rim of the nest, presumably to improve ventilation of the nest during fanning at a time when the eggs are more metabolically active. Once the young hatch, the male attempts to keep them together for a few days, sucking up any wanderers into his mouth and spitting them back into the nest. Afterwards, the young disperse and the nest is either abandoned by the male, or repaired in preparation for another breeding cycle.
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The high binding affinity to the cell wall substrate (close to that of IgG for its substrate) of each lysin appear to be reason why multiple molecules are required, since every lysin binds so tightly to the cell wall that it can't break enough bonds to cause lysis by itself. In order to reach the cell wall, phage lysins have to cross the cell membrane. However, they generally lack a signal peptide that would allow them to do so. In order to solve such a problem, phage viruses synthesize another protein called holin which binds to the cell membrane and makes holes in it (hence its name), allowing lysins to reach the peptidoglycan matrix.
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