Sentences Generator
And
Your saved sentences

No sentences have been saved yet

180 Sentences With "laboratory animal"

How to use laboratory animal in a sentence? Find typical usage patterns (collocations)/phrases/context for "laboratory animal" and check conjugation/comparative form for "laboratory animal". Mastering all the usages of "laboratory animal" from sentence examples published by news publications.

type: All Declarative Interrogative Exclamative

structure: All Simple Compound Complex Compound-Complex

length: All <=10 words 10-20 words 20-30 words 30-50 words

Laboratory animal studies have shown effects on the liver and reproduction.
Correction: A previous version of this story wrongly attributed laboratory animal deaths to the University of Michigan.
This will ultimately enhance laboratory animal welfare and scientific discovery, human and animal health, food safety and the nation's future.
The ever-thorough Bilott discovers old laboratory animal studies that DuPont and 3M, which manufactured PFOA, had conducted decades earlier.
We've seen him dissect the physical ailments and qualities of Hillary Clinton the way he would a farm or laboratory animal.
Laboratory animal testing, particularly on rodents, has long been an important means for determining the toxicity of chemicals and other environmental contaminants.
Their article was half-prospectus and half-plea — a call to fellow physiologists to make the Burmese python a standard laboratory animal.
The four remaining survived for 90, 90, 182, and 195 days—all of them were euthanized as required by prior approval and laboratory animal guidelines.
The best laboratory animal would not only get infected and get sick, but get sick in the same way that humans do, showing a similar course of disease.
For Benedict, the python's Olympian feats of digestion made it worthy of study, but he was nearly as impressed by its placid disposition — a highly valued trait in a laboratory animal.
Each of the strange events was described by the university in a separate letter to the National Institutes of Health (NIH) Office of Laboratory Animal Welfare, which provides oversight to recipients of grant funding.
More research and more laboratory, animal, and later human tests will need to be done before the research from Boston University can become a real-life medicine people with red hair can take to prevent skin cancer.
Over the past four decades, regulations and guidance from the United States Department of Agriculture, the National Research Council, the American Veterinary Medical Association and the Office of Laboratory Animal Welfare have undergone substantial refinement aimed at improving compliance with standards for animal well-being, care and housing.
"As part of that oversight, and in the interest of full transparency, the [university] self-reported each of these events to the National Institute of Health's Office of Laboratory Animal Welfare...[which] found [the university] took all necessary steps to self-report and correct these isolated incidents," the spokesperson added.
To date, several of our oxime drugs have been as good as or more effective than 2-PAM for increasing 24-hour survival for animals exposed to lethal doses of OPs, using highly relevant mimics of two nerve agents sarin and VX, as well as an insecticidal chemical in a laboratory animal model.
A Registered Laboratory Animal Technician has an animal science education, training in the care and use of laboratory animals and on the job practical experience. Associate Registered Laboratory Animal Technician These individuals have several years of experience in the field and an interest in continuing their education. An ARLAT is trained for the care and use of laboratory animals. Registered Laboratory Animal Technician The Registered Laboratory Animal Technician (RLAT) and Registered Laboratory Animal Technician (Research) (RLAT(R)) are equivalent designations.
He retired from the Army in 1983 with the rank of Colonel. After the Army, Rozmiarek spent the next two decades in academia as a professor of laboratory animal medicine. In 1983 he went to The Ohio State University where he served as Professor of Laboratory Animal Medicine and Director of University Laboratory Animal Resources through 1986. In 1987 he joined the University of Pennsylvania as University Veterinarian and Professor and Director of University Laboratory Animal Resources.
He moved to Toronto in 1967 and began working for the Division of Laboratory Animal Science at the University of Toronto. He founded the American Association of Laboratory Animal Science, serving first president.
AALAS publishes two scientific journals, Comparative Medicine and the Journal of the American Association for Laboratory Animal Science, as well as a member magazine, Laboratory Animal Science Professional. Publications are produced in the AALAS national office in Memphis, TN.
National Centre for Laboratory Animal Sciences (NCLAS) is established in India in 1957, for spreading knowledge on the Care, Breeding, Management and Experimentation using laboratory animals in biomedical research. It started as a unit called Laboratory Animal Information Service (LAIS) at the Indian Cancer Research Centre, Bombay way back in 1957 and this unit was later shifted to National Institute of Nutrition ( NIN ), Hyderabad in 1976. it was renamed then as Laboratory Animal Information Service Centre (LAISC). In 1998, during the 7th Five Year Plan, additional support came from Department of Biotechnology (DBT) under the Ministry of Science and Technology, Government of India, which helped the unit to become the National Center for Laboratory Animal Sciences (NCLAS).
The National Laboratory Animal Center (NLAC) is a research institute in Taiwan which is part of the National Applied Research Laboratories.
The symposium is the only laboratory animal conference held each year in Canada and attracts more than 400 members from the industry.
The Institute for Laboratory Animal Research of the United States National Research Council has produced guidelines for the transportation of research animals.
Hemorrhagic fever with renal syndrome: mode of transmission to humans. Laboratory Animal Science. 37: 95-104.Schamljohn, C. S., AND B. Hjelle. 1997.
The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care, or AAALAC. In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). The name change reflects the organization's growth in other countries, and its commitment to enhancing life sciences and quality animal care around the world.
Typically RMLAT's are in supervisory positions or are candidates for such positions. They are able to compile facts, analyze the consequences of different approaches to any given animal research related problem and apply their knowledge in problem- solving and decision-making situations. RMLAT(R): Registered Master Laboratory Animal Technician (Research) The background is similar to the RMLAT Registration but is applied to those individuals who have been involved primarily with specific laboratory animal species and projects. The individual has a laboratory animal science knowledge base enabling them to be a major contributor to a successful research program.
The Journal of the American Association for Laboratory Animal Science (JAALAS) serves as an official communication vehicle for the American Association for Laboratory Animal Science (AALAS). The journal, published bi-monthly, includes a section of refereed articles and a section of AALAS association news. The mission of the refereed section of the journal is to disseminate high-quality, peer-reviewed information on animal biology, technology, facility operations, management, and compliance as relevant to the AALAS membership. Reflecting this mission, the journal title has changed, effective with the first issue of 2006, from Contemporary Topics in Laboratory Animal Science (CT) to JAALAS.
Laboratory, animal, and other pre-clinical studies suggest that BLT2 receptors may be involved not only in inflammation and allergy but also in human cancer.
Each spring since 1962, CALAS has held a national Symposium. The CALAS Symposium is a networking and educational event for the laboratory animal science community in Canada. It brings members and non- members together for four days of knowledge building workshops, discussions, demonstrations and networking. Eleven professional and technical awards for recognition in the field of laboratory animal science are presented each year at the symposium.
Comparative Medicine (CM), an international bi- monthly journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. It seeks to advance knowledge about comparative medicine and laboratory animal science through the publication of scholarly articles about animal models, animal biology, laboratory animal medicine, laboratory animal pathology, animal behavior, animal biotechnology, and related topics. The journal invites reports and reviews about basic and applied laboratory investigations, clinical investigations, and case studies. It also welcomes informed and thoughtful opinions relevant to the humane care and use of laboratory animals.
The person has in depth knowledge about their research project and the animal species they are working with. Their knowledge includes understanding how animal husbandry, the environment, and the operation of an animal facility affect their research. RMLAT: Registered Master Laboratory Animal Technician The Master's achievement is the highest level of Registration. Successful candidates possess a knowledge of most laboratory animal species, their care, management and use in research.
In 1991, Vergara was nominated by the Spanish Society for Laboratory Animal Science (SECAL) as their scientific representative to the International Council for Laboratory Animal Science (ICLAS). She was later elected by the ICLAS General Assembly to serve on the ICLAS Governing Board as Treasurer from 1999 to 2003 and then as the first woman ICLAS Secretary General from 2003 to 2007. In 2011, she was elected ICLAS's first woman President.
The faculty offers general training in veterinary medicine, health risk management, medicine and health risks in southern countries, equine dentistry, food chain control, food safety, equine orthopaedics, equine revalidation and beekeeping. It also organises the necessary training to award the legal titles of Master of Experiment, laboratory animal caretakers and technicians, accredited by Felasa (the Federation of European Laboratory Animal Science Associations), which are compulsory for experimentation using laboratory animals.
Today, these three principles are central to the laws and guidelines governing the use of animals and research. In the U.S., the Animal Welfare Act of 1970 (see also Laboratory Animal Welfare Act) set standards for animal use and care in research. This law is enforced by APHIS’s Animal Care program see AWA policies. In academic settings in which NIH funding is used for animal research, institutions are governed by the NIH Office of Laboratory Animal Welfare (OLAW).
AFRIMS also has the largest medical library in Southeast Asia and a modern research animal facility, which is accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC).
The Institute for Laboratory Animal Management (ILAM) is an AALAS educational program developed to provide instruction in management concepts that is applicable to the laboratory animal science industry and to enhance communication, team building, and networking among colleagues with mutual interests. Directors, managers, and supervisors of laboratory animal facilities have seen their roles grow more and more complex over the years, and they have found themselves in a unique profession. People in management positions must be able to interpret the social, political, and economic environments in which they operate and use administrative and technical skills to maintain and improve their animal care and use programs. The vast majority of people in these positions was trained in biologic and veterinary sciences and must find additional training in management skills to fulfill their administrative roles.
Patri Vergara is a Professor in Physiology at the Veterinary Faculty, at the Universidad Autónoma de Barcelona, Spain and in 2011, was elected the first woman President of the International Council for Laboratory Animal Science.
A Syrian hamster Syrian hamster care includes all the actions which a person might take to promote animal welfare in the Syrian hamster when it lives with humans either as a pet or laboratory animal.
Currently, the Guide is in its eighth edition.NABR Animal Law Section — Research Animal Protection Section An accreditation committee was formed in 1963, and it was independently incorporated from the ACP. Its name was AAALAC, the American Association for the Accreditation of Laboratory Animal Care. In 1996 this committee changed its name to the "Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC)" A series of reports on poor animal welfare in the US led to a major article in Life magazine in 1966.
Michael Balls (born 1938) is a British zoologist and professor emeritus of medical cell biology at the University of Nottingham. He is best known for his work on laboratory animal welfare and alternatives to animal testing.
Overall, this movement had little legislative success until the passing of the Laboratory Animal Welfare Act, in 1966.Buettinger, Craig (1 January 1993) Antivivisection and the charge of zoophil-psychosis in the early twentieth century. The Historian.
Carbone, Larry. (2004). What Animals Want: Expertise and Advocacy in Laboratory Animal Welfare Policy. Mice, rats, fish, amphibians and reptiles together account for over 85% of research animals. Most animals are euthanized after being used in an experiment.
Murphy received her V.M.D. and Ph.D. from the University of Pennsylvania. She completed a postdoctoral fellowship in the department of comparative medicine at Johns Hopkins University and is a diplomate of the American College of Laboratory Animal Medicine.
Zhang, Y. P., Onifer, S. M., Burke, D. A., & Shields, C. B. (2001). A topical mixture for preventing, abolishing, and treating autophagia and self-mutilation in laboratory rats. American Association for Laboratory Animal Science, 40(2), 35-36.
Association for Assessment and Accreditation of Laboratory Animal Care, Accessed 06 September 2007 a non-governmental, nonprofit association, is regarded by the industry as the "gold standard" of accreditation. "AAALAC Accreditation Visit" ILACUC Newsletter. Ohio State University. September, 2005.
It is not uncommon for an infected animal to die within 1–10 days of disease contraction. During necropsy, inflammation of the ileum, cecum, and colon are commonly present.Loew, Franklin, Fred Quimby, Lynn Anderson, and James Fox. Laboratory Animal Medicine.
The center receives unannounced bi-annual inspections by the United States Department of Agriculture. It has been accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International since 1975. As required by the Animal Welfare Act, the center also maintains an Institutional Animal Care and Use Committee; each IACUC must consist of at least one veterinarian with training in laboratory animal science and expertise in the species under consideration, at least one practicing research scientist, and at least one person not affiliated with the institution to represent community interests in proper care and use of animals.
Attempts to reproduce the disease in mice, the standard laboratory animal model, also failed. The disease was finally produced in guinea pigs. The CDC announced the discovery at a press conference on January 18, 1977. The bacterium was later named Legionella pneumophila.
ICLAS Monitoring Center was established in the CIEA in 1979 and is the only center in the world for testing and verifying the quality of laboratory animals, under the direction of Dr. Tatsuji Nomura with a conduct of International Council for Laboratory Animal Science (ICLAS).
The Canadian Association for Laboratory Animal Science (CALAS), a not-for- profit membership association was formed in 1962 with a vision to elevate the standards of laboratory animal science and to enhance animal well-being. They embarked on a goal to work towards the elimination of inhumane and unnecessary use of animals in research. The CALAS mission is to advance the knowledge, skills and status of those who care for and use laboratory animals, to improve the standards of animal care in research and to provide a forum for the exchange and dissemination of knowledge regarding care and research. CALAS has 900 members, being veterinarians, physicians, researchers, administrators and technicians.
Their placental structure is similar to that of humans, and their gestation period can be divided into trimesters that resemble the stages of fetal development in humans.Elsevier Academic Press(2012). "The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents" p. 705 American College of Laboratory Animal Medicine. .
Laboratory Animal Science 27:38–42. Most behaviour changes have not been demonstrated to lead to fitness gains in either the host or the parasite.Pullin, R. (1995) “Adaptive” changes in the behaviour of parasitized animals: A critical review. International Journal for Parasitology 25 (12): 1371–1383.
Best, Steven. Terrorists or Freedom Fighters? Lantern Books, 2004, , p. 20. Logo of the Animal Liberation Front In August 1974, Lee and Goodman were arrested for taking part in a raid on Oxford Laboratory Animal Colonies in Bicester, which earned them the name the "Bicester Two".
Eight professional and technical awards for excellence in the field of laboratory animal science are given each year at the AALAS National Meeting. The AALAS National Meeting is the largest gathering in the world of professionals concerned with the production, care, and use of laboratory animals.
Whitney is a diplomate of the American College of Laboratory Animal Medicine and served as chief veterinary officer of the Public Health Service from 1985 to 1989. His awards include the U.S. Public Health Service Distinguished Service Medal and the Legion of Merit for his US Army service.
It is caused by the spore-forming bacterium Clostridium piliforme, formerly known as Bacillus piliformis.Hansen, A. K., Andersen H. V. and S. O. 1994. Studies on the diagnosis of Tyzzer’s disease in laboratory rat colonies with antibodies against Bacillus piliformis (Clostridium piliforme). Laboratory Animal Science 44:424-429.
Laboratory animal allergy (LAA) is an occupational disease of laboratory animal technicians and scientists. It manifests as an allergic response to animal urine, specifically the major urinary proteins (Mups) of rodents, and can lead to the development of asthma. A study of 5641 workers in Japan who were exposed to laboratory animals found 23.1% had one or more allergic symptoms; globally the prevalence among at risk workers is estimated between 11 and 30% According to the National Institutes of Health, prevention of animal allergy depends on the control of allergens in the work environment. This involves a combination of measures to eliminate or control allergen exposure, including engineering controls, administrative controls, and personal protective equipment.
In 2009, there were a total of 130 companies based in the park and sales totaled NT$461 billion. Key industries in the park include integrated circuits, optoelectronics, green energy, and biotechnology. Prominent companies based in the park include the National Laboratory Animal Center, TSMC, InnoLux Corporation, and United Microelectronics Corporation.
The altered Schaedler flora (ASF) is a community of eight bacterial species: two Lactobacilli, one Bacteroides, one spiral bacteria of the Flexistipes genus, and four extremely oxygen sensitive (EOS) Fusobacterium species.[Fox, J., Anderson, L., Loew, F. and Quimby F. Laboratory animal medicine. 2nd Ed. 2002. Academic Press. 46-47.
More recent research has shown that ice water is faster and less stressful than anaesthetics for killing tropical ornamental fishes like zebrafish.Wilson et al. 2009.Evaluation of Rapid Cooling and Tricaine Methanesulfonate (MS222) as Methods of Euthanasia in Zebrafish (Danio rerio). Journal of the American Association for Laboratory Animal Science 48, 785–789.
Reportedly it had some success in these goals. The air crib was a controversial invention. It was popularly mischaracterized as a cruel pen, and it was often compared to Skinner's operant conditioning chamber (aka the 'Skinner Box'). This association with laboratory animal experimentation discouraged its commercial success, though several companies attempted production.
30 Years of the Animal Welfare Act. Animal Welfare Information Center Bulletin 8: 1-2, 23. Although Congress discussed laboratory animal welfare in the early 1960s, there was not enough interest to pass legislation until articles published by Sports Illustrated and Life in 1965 and 1966, respectively, generated a public outcry.Stevens, C. (1990).
He was a contributing author to the IACUC Handbook. Rozmiarek represented the United States as the National Member to the International Council for Laboratory Animal Science (ICLAS) from 2003-2013; was elected to the ICLAS Governing Board in 2007; and served as Secretary-General, 2011-2013, at the time of his death. ICLAS is an international scientific organization advancing human and animal health by promoting the ethical care and use of laboratory animals in research worldwide. Rozmiarek was the recipient of numerous awards for his lifetime of accomplishments in the area of laboratory animal care: the AALAS Research Award (1983); the AALAS Griffin Award (1995), the AVMA Charles River Prize (1996); the AAALAC Bennett J. Cohen Award (2012); the AALAS Nathan R. Brewer Lifetime Achievement Award (2013).
Many scientists like Jianfei Wang, the director of laboratory animal science at GlaxoSmithKline Research and Development Center in China, maintain that China has made considerable progress to work towards animal protection and welfare, especially considering that the concept of laboratory animal science did not exist in China until the late twentieth century. According to Wang, international collaboration with research institutions have brought animal welfare concepts from abroad back to China. Additionally, as China gets more involved in international trade, there are many pressures placed on China throughout the world over concerns for animal welfare and protection. For example, organizations like PETA were instrumental with stopping a shipment research primates from Chinese laboratories to Los Angeles, the U.S.'s largest port of entry for research primates.
Festing is the author of over 200 scientific papers on laboratory animal genetics and related issues. He has a particular interest in improving the design of animal experiments, particularly in the area of toxicology testing. He has written books cataloguing laboratory animals, including International Index of Laboratory Animals and Inbred Strains in Biomedical Research.
The School of Life Science pursues questions fundamental to our understanding of biology and diseases. It also develops enabling technologies and methods to improve human health and life. The University has launched the Advanced Biomedical Technology Core Facility and the Laboratory Animal Resource Center. The Core Facility has established a series of research platforms.
Harry Rozmiarek (March 27, 1939 – June 15, 2013) was a noted veterinarian, academic, and laboratory animal care specialist. Rozmiarek was born in Pulaski, Wisconsin. He graduated from the University of Minnesota in 1962 with a veterinary degree. He joined the United States Army and was assigned as an attending army veterinarian at Fort Myer, Virginia.
Many academic research institutes seek accreditation voluntarily, often through the Association for Assessment and Accreditation of Laboratory Animal Care, which maintains the standards of care found within The Guide for the Care and Use of Laboratory Animals and the PHS policy. This accreditation is, however, not a prerequisite for federal funding, unlike the actual compliance.
The United States' government responded by proclaiming these dogs as heroes. The Cold War sparked a heated debate over the ethics of animal experimentation in the U.S., particularly aimed at how canines were treated in World War II. In 1966, major reforms came to this field with the adoption of the Laboratory Animal Welfare Act.
Hediste diversicolor is used as a model laboratory animal for research. It has also been used to evaluate the quality of marine sediment because it bioaccumulates certain heavy metals such as lead, cadmium, chromium and arsenic. Anglers use it for bait when sea fishing, digging it out of the substrate with a large fork. It is also available commercially.
Temple University Press, 1995, p. 192; Magnuson, Warren G., Chairman. "Opening remarks in hearings prior to enactment of Pub. L. 89-544, the Laboratory Animal Welfare Act," U.S. Senate Committee on Commerce, 25 March 1966. The USDA recovered at least a dozen stolen pets during a raid on a Class B dealer in Arkansas in 2003.
APHIS is granted specific authority under several federal statutes: Animal Health Protection Act, et seq. Governs the prevention, detection, control, and eradication of diseases and pests of animals, where "animal" is defined as "any member of the animal kingdom (except a human)." (1) (West 2009). Animal Welfare Act (Laboratory Animal Welfare Act of 1966), et seq.
Laboratory Animal Welfare. In: Animals and Their Legal Rights, Animal Welfare Institute: Washington, D.C., p. 66-111. The first article, written by Coles Phinizy, appeared in the November 29, 1965, issue of Sports Illustrated. The piece detailed the story of Pepper the Dalmatian, a dog that disappeared from the yard of the Lakavage family home in Pennsylvania.
A 2016 systematic review of laboratory animal studies and preliminary human clinical trials using commercially available strains of probiotic bacteria found that certain species of the Bifidobacterium and Lactobacillus genera (i.e., B. longum, B. breve, B. infantis, L. helveticus, L. rhamnosus, L. plantarum, and L. casei) had the most potential to be useful for certain central nervous system disorders.
He is a member of the Task Force on Stem Cell Research and Regenerative Medicine of the Department of Biotechnology of the Government of India and has delivered guest lectures on the subject. He also serves as a member of the editorial board of the Journal of Animal Science of the Laboratory Animal Scientists' Association (India).
The American Association for Laboratory Animal Science (AALAS) is a 501(c)(3) nonprofit membership association, established in 1950 as a forum for the exchange of information and expertise in the care and use of laboratory animals. Membership consists of approximately 12,000 individual, institutional, commercial and affiliate members. The national office is located in Memphis, TN.
NAMRU-3 is the first overseas Department of Defense research laboratory to receive the College of American Pathologists (CAP) Laboratory Accreditation for infectious diseases clinical diagnostics. NAMRU-3 is the only research institution in North Africa with an AAALAC International (Association for Assessment and Accreditation of Laboratory Animal Care International) accredited animal research facility and is one of only two institutions in Africa with a Biosafety Level 3 (BSL-3) laboratory. Animal research conducted at NAMRU-3 is subject to approval by an Institutional Animal Care and Use Committee (IACUC) and is focused on tropical viral, bacterial and parasitic diseases; infection of blood-feeding arthropods; and tissue harvesting techniques training. In addition to these assets, NAMRU-3 has modern laboratory spaces, a centralized medical library and access to the US National Library of Medicine.
Expansion, acquisition, relocation and new product development became Vollrath's credo. A new foundry was dedicated in early 1965. In April 1968 the newly erected fabrication building was dedicated during an open house. The 400 by building was constructed for production of the mobile equipment line and the new line of laboratory animal housing units for primates, dogs, cats, rabbits and rodents.
AWA policies. In academic settings in which NIH funding is used for animal research, institutions are governed by the NIH Office of Laboratory Animal Welfare (OLAW). At each site, OLAW guidelines and standards are upheld by a local review board called the Institutional Animal Care and Use Committee (IACUC). All laboratory experiments involving living animals are reviewed and approved by this committee.
Carbone, p. 22. Sources of laboratory animals vary between countries and species; most animals are purpose-bred, while a minority are caught in the wild or supplied by dealers who obtain them from auctions and pounds."Use of Laboratory Animals in Biomedical and Behavioral Research", Institute for Laboratory Animal Research, The National Academies Press, 1988 .Cooper, Sylvia (1 August 1999).
Dealers that breed animals for sale to pet stores must be in compliance with AWA regulations. Animal dealers are people who sell animals bred at their facility. Examples of dealers include pet and laboratory animal breeders and brokers, auction operators, and everyone who sells exotic or wild animals, or dead animals or their parts. They must be licensed under class "A" or "B".
One of these members must be a Doctor of Veterinary Medicine with training or experience related to laboratory animal research :3. One member must have no relation with the institution except for serving on the IACUC. Additionally, if the committee consists of more than three members, more than three members can be from the same administrative unit of the facility.
In 2006, China issued the Guidelines on the Humane Treatment of Laboratory Animals. These guidelines mention, for the first time in China's formal policy and regulations, the words "animal welfare". This regulation was issued in addition to other laboratory animal- related policies in China like the 1988 Statute on the Administration of Laboratory Animals, 1997 Laboratory Animal Development Program for the Ninth Five-Year Plan, the 2005 Guidelines on Beijing Municipality on the Review of Welfare and Ethics of Laboratory Animals. Unlike the 1988 Statute on the Administration of Laboratory Animals which focuses solely on controlling the quality of the laboratory animals being tested on, the Guidelines on the Humane Treatment of Laboratory Animals officially expands into the realm of animal welfare and protection through addressing problems in procurement, husbandry, environmental conditions, experimental usage and transportation.
The unit makes contributions to Botany, Zoology, Morphology, and Parasitology. To assist researchers and teachers, ICB has four laboratory animal facilities with hundreds of guinea pigs kept in accordance to international principles of animal experimentation. The university operates the Federal University of Minas Gerais Ecological Station on the Pampulha campus, used for various research projects including a Master's course in Ecology Conservation and Wildlife Management.
Sorely realizing the insensitivity of his program, Thomas decides to show Sirius the university, where he marvels in awe. Sirius is acquainted with his creator's most trusted colleagues and scientists. They soon begin to study his mind and body. Months pass, and his new life as a pampered laboratory animal takes a toll on his physical and mental well-being, becoming overweight and agitated.
He also performed fourteen executions in New Jersey and was the executioner for six executions in Connecticut during the mid-1950s to early 1960s. Hover was married since he was 20 and had two children. He was the founder of a laboratory animal supply company, Taconic Farms, that he later sold. Hover held a General Class amateur radio license, since some time before 1969.
In the U.S., laboratory mice are not regulated under the Animal Welfare Act administered by the USDA APHIS. However, the Public Health Service Act (PHS) as administered by the National Institutes of Health does offer a standard for their care and use. Compliance with the PHS is required for a research project to receive federal funding. PHS policy is administered by the Office of Laboratory Animal Welfare.
The National Laboratory Animal Center was established in 1994 as the first large scale domestic supplier of specific pathogen free (SPF) laboratory rodents. In June 2003 it was brought under the umbrella of the National Applied Research Laboratories. NLAC supports Taiwan's biomedical industry. In 2015 NLAC succeeded in breeding their first advanced severe immuno deficiency (ASID) mouse which they established a commercial line off of.
Each fall since 1950, the American Association for Laboratory Animal Science has held its annual National Meeting. During the five days of the meeting, members and nonmembers participate in workshops, lectures, poster sessions, and exhibits. The program is designed to have topics relevant to the entire membership. Exhibitors have an opportunity to interact with AALAS members from the academic community, research institutions, government organizations, and commercial companies.
High- throughput sequencing platform – Molecular Biology Flow cytometry – Immunology Primate Experimental Medicine & Surgery Unit National Center for Laboratory Animal Sciences Microscopy – Biochemistry Confocal Microscopy – Biochemistry The institute carries out research and patent development in clinical nutrition, outcomes research, pharmacology, pathology, toxicology, food chemistry, endocrinology, molecular biology, regenerative medicine,Tissue and Cell, v.43, no.4, 2011 August, p.266(5) () community nutrition, ophthalmology, and sports nutrition.
For the past century, the measurement of pain in rodent biomedical research was considered complicated and imprecise, and many researchers suggested there is a mismatch between human clinical pain symptoms and established procedures in rodents. Based on the human Neonatal Facial Coding Scale, which is itself based on the Facial Action Coding System, Mogil and colleagues developed the Mouse Grimace Scale and the Rat Grimace Scale. The original findings were highly cited, widely covered in the scientific press, and Mogil was awarded the Bennet Cohen Award from the International Council for Laboratory Animal Science and the SGV Award from the Swiss Laboratory Animal Science Association for the finding. Grimace scales are now routinely used in institutional veterinary settings for the determination of post-operative pain in animals, and have been developed for 10 species: mice, rats, rabbits, cats, horses, cows, pigs, sheep, ferret, and seal.
Robert Goulet guest stars. # Astronaut Day (January 17, 2001) Part 2 of 2—Still in Atlantic City, the Anipals attempt to "unstick" Triumph before his big show. Meanwhile, Doug tries to achieve weightlessness. # Chinese New Year's Day (January 24, 2001)—The Anipals ditch the Funhouse to enter the lucrative, glamorous world of laboratory animal testing, as Doug celebrates Chinese New Year's Day and makes fireworks with a panda.
Kainate receptors likely control a sodium channel that produces excitatory postsynaptic potentials (EPSPs) when glutamate binds. Kainic acid is commonly injected into laboratory animal models to study the effects of experimental ablation. Kainic acid is a direct agonist of the glutamic kainate receptors and large doses of concentrated solutions produce immediate neuronal death by overstimulating neurons to death. Such damage and death of neurons is referred to as an excitotoxic lesion.
Gusmer's manufacturing sites are located in Fresno, CA and Waupaca, WI. Fresno manufactures depth filters, oak alternatives, cellulose filter aids, and fermentation nutrients. The Waupaca facility primarily manufacturers depth filtration media for pharmaceutical applications, fryer oil filters, laboratory animal bedding as well as various specialty products. Waupaca has recently undergone several expansions to add capacity for its pharmaceutical partnership products. In 2008 the plant significantly expanded its molding capabilities.
Visscher was the 20th president of the American Physiological Society, serving from 1948 to 1949. He was elected a member of the National Academy of Sciences in 1956. He also served as a co-founder and president of the National Society for Medical Research, as secretary general of the International Union of Physiological Sciences, and as founding chairman of the American Association for Accreditation of Laboratory Animal Care.
He obtained this position with assistance from Carl Rokitansky (1804–1878). In 1875, he became a professor of forensic medicine at the University of Vienna.ADB:Hofmann, Eduard Ritter von In: Allgemeine Deutsche Biographie Hofmann is remembered for his diligent work in development of forensic medicine as a separate scientific entity. He is credited for introducing and expanding methodologies such as microscopy, spectroscopy and laboratory animal experimentation into forensic medicine at Vienna.
Years later, animals of this original breeding colony were exported to the US, where Syrian hamsters became a common pet and laboratory animal. Comparative studies of domestic and wild Syrian hamsters have shown reduced genetic variability in the domestic strain. However, the differences in behavioral, chronobiological, morphometrical, hematological, and biochemical parameters are relatively small and fall into the expected range of interstrain variations in other laboratory animals.Kuhnen, G. (2002).
The use of non- human animals in research: a guide for scientists The Royal Society, 2004, p. 1 The Institute for Laboratory Animal Research of the United States National Academy of Sciences has argued that animal research cannot be replaced by even sophisticated computer models, which are unable to deal with the extremely complex interactions between molecules, cells, tissues, organs, organisms and the environment."Science, Medicine, and Animals", Institute for Laboratory Animal Research, Published by the National Research Council of the National Academies 2004, p. 2 Animal rights organizations—such as PETA and BUAV—question the need for and legitimacy of animal testing, arguing that it is cruel and poorly regulated, that medical progress is actually held back by misleading animal models that cannot reliably predict effects in humans, that some of the tests are outdated, that the costs outweigh the benefits, or that animals have the intrinsic right not to be used or harmed in experimentation.
The National Institutes of Health Laboratory Animal Allergy Prevention Program The protein product of the mouse Mup17 gene, known as Mus m 1, Ag1 or MA1, accounts for much of the allergenic properties of mouse urine. Similarly, the product of the rat Mup13 gene, Rat n 1, is also a potent human allergen. One study found that two thirds of laboratory workers who had developed asthmatic reactions to animals had antibodies to Rat n 1.
There are about 70 inspectorsCompliance Inspections Animal Welfare – USDA Animal and Plant Health Inspection Service, Accessed 06 September 2007 monitoring around 1100 research institutions. The inspectors also conduct pre- licensing checks for sites that do not engage in animal research or transportation, of which more than 4000 exist (e.g. dog kennels). Another regulatory instrument is the Office of Laboratory Animal Welfare (OLAW), which is an office within the US National Institutes of Health.
The Animal Welfare Act of 1966 set standards of treatment of animals in research experiments. It requires all research facilities to register with the USDA and allows officials to conduct unannounced facility inspections. The Health Research Extension Act of 1985 requires that all research facilities using animals establish Institutional Animal Care and Use Committees (IACUCs) to evaluate twice a year the institutions' activities involving animals. The IACUCs report to the NIH Office of Laboratory Animal Welfare annually.
Allergic symptoms, including rhinitis, conjunctivitis, and asthma, have been documented in laboratory animal workers who come into contact with guinea pigs. Allergic reactions following direct exposure to guinea pigs in domestic settings have also been reported. Two major guinea pig allergens, Cav p I and Cav p II, have been identified in guinea pig fluids (urine and saliva) and guinea pig dander. People who are allergic to guinea pigs are usually allergic to hamsters and gerbils, as well.
As of May 2011, the Penn State College of Medicine has graduated 3,907 physicians (M.D.) and 1,004 scientists with Ph.D. or M.S. degrees. The College of Medicine offers degree programs in anatomy, bioengineering, biomedical sciences, bioinformatics and genomics, genetics, immunology and infectious diseases, integrative biosciences, molecular medicine, molecular toxicology, neuroscience, pharmacology, and physiology. Two postdoctoral programs leading to an M.S. degree are offered, namely in Laboratory Animal Medicine, the only such program in Pennsylvania, and Public Health Sciences.
In 1990 Sundqvist expanded his work to include radio comedy. He wrote several humorous shows for the radio station formerly known as Radiomafia, including Tietokoneenkorjauskurssi ("Computer repair course") and Koe-eläinpuisto ("Laboratory animal park"). Leevi and the Leavings started their career at the end of the 1970s, but became popular in wider circles in the second half of the 80s. Their first hits included "Pohjois-Karjala", "Teuvo, maanteiden kuningas", "Sopivasti lihava", "Amalia" and "Rin Tin Tin".
The locust is large and easy to breed and rear, and is used as an experimental model in research studies. It has been used in evolutionary biology research and to discover to what degree conclusions reached about other organisms, such as the fruit fly (Drosophila) and the housefly (Musca), are applicable to all insects. It is a suitable school laboratory animal because of its robustness and the ease with which it can be grown and handled.
Example LLW includes wiping rags, mops, medical tubes, laboratory animal carcasses, and more. LLW waste makes 94% of all radioactive waste volume in the UK. Some high-activity LLW requires shielding during handling and transport but most LLW is suitable for shallow land burial. To reduce its volume, it is often compacted or incinerated before disposal. Low-level waste is divided into four classes: class A, class B, class C, and Greater Than Class C (GTCC).
Its small stature and short generation time facilitates rapid genetic studies,About Arabidopsis on The Arabidopsis Information Resource page (TAIR) and many phenotypic and biochemical mutants have been mapped. A. thaliana was the first plant to have its genome sequenced. Among vertebrates, guinea pigs (Cavia porcellus) were used by Robert Koch and other early bacteriologists as a host for bacterial infections, becoming a byword for "laboratory animal," but are less commonly used today. The classic model vertebrate is currently the mouse (Mus musculus).
The IACUC must ensure that alternatives, including non-animal alternatives, have been considered, that the experiments are not unnecessarily duplicative, and that pain relief is given unless it would interfere with the study. The IACUCs regulate all vertebrates in testing at institutions receiving federal funds in the USA. Although the provisions of the Animal Welfare Act do not include purpose-bred rodents and birds, these species are equally regulated under Public Health Service policies that govern the IACUCs.Office of Laboratory Animal Welfare.
He retired from the University of Pennsylvania in 2004. He was the Director of Laboratory Animal Medicine and Facilities at the Fox Chase Cancer Center in Philadelphia, Pennsylvania from 2004 until his death in 2013. During his career, Rozmiarek was active in the development of guidelines for the proper care and use of laboratory animals in research. He served in leadership positions of national and international organizations that promote the humane treatment of animals in science including AAALAC, AALAS, ACLAM, and ICLAS.
Laboratory animal suppliers in the United Kingdom breed animals such as rodents, rabbits, dogs, cats and primates which they sell to licensed establishments for scientific experimentation. Many have found themselves at the centre of animal rights protests against animal testing.Conn, P. Michael and Parker, James V (2008). The Animal Research War, Palgrave Macmillan, Campaign methods have included leafleting, demonstrations, verbal and physical intimidation, false accusations of criminal activity such as paedophilia, destruction of property, arson, the use of explosive devices and a grave- robbing.
From 1989 to 1992, he was director of the NIH National Center for Research Resources. Prior to joining the PHS, Whitney was director of the U.S. Army training program in laboratory animal medicine and served a year in Vietnam (1970) as commander of a veterinary medical detachment. He retired from the USPHS in 1994, and co-founded "Earthspan", a non-profit organization dedicated to advanced technologies to conserve biodiversity, ecosystems, and environmental health. Whitney served as president of Earthspan, until his retirement in 2008.
Studies of human diseases have benefited from the availability of small laboratory animal models. However, the tissues of animal models with a GULO gene generally have high levels of ascorbic acid and so are often only slightly influenced by exogenous vitamin C. This is a major handicap for studies involving the endogenous redox systems of primates and other animals that lack this gene. Guinea pigs are a popular human model. They lost the ability to synthesize L-gulono-gamma-lactone oxidase 20 million years ago.
An individually ventilated and sealed cage for laboratory mice Mice are the most commonly used mammalian laboratory animal, due to their relatively close relationship, and associated high homology, with humans, their ease in maintenance and handling, and their high rate of reproduction. Laboratory mice typically belong to standardized inbred strains selected for the stability or clarity of specific harmful mutations. This allows research with laboratory mice to easily restrict genetic and biological variables, making them very useful model organisms in genetic and medicinal research.
Van den Berg was assigned as Payload Specialist on STS-51B Challenger (April 29–May 6, 1985). STS-51B, the Spacelab-3 mission, was launched from the Kennedy Space Center, Florida, and returned to land at Edwards Air Force Base, California. It was the first operational Spacelab mission. The seven-man crew aboard Challenger conducted investigations into crystal growth, drop dynamics leading to containerless material processing, atmospheric trace gas spectroscopy, solar and planetary atmospheric simulation, cosmic rays, and laboratory-animal and human medical monitoring.
Each local IACUC reviews research protocols and conducts evaluations of the institution's animal care. The evaluations include inspections of all animal use facilities every six months. The IACUC reports to the NIH Office of Laboratory Animal Welfare (OLAW) annually, and is issued an animal welfare assurance number by OLAW without which no federally funded use of animals in research may occur. The IACUC is required to report significant noncompliance with animal use protocols to OLAW, as well as IACUC actions taken to correct the noncompliance.
Animal Company In rodent diets, standardized research methods will reduce the fluctuation in study results. Envigo's Teklad business unit provides both high-fat and control diets mostly used in the research of impact of obesity and nutrition on disease states like diabetes, cancer and heart disease. Three of Envigo’s breeding sites have been accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International Council including Horst, the Netherlands (March 29, 2016), Bresso, Italy, and Wyton, United Kingdom (July 19, 2016).
The central theme of the Center for Molecular Medicine and Infectious Diseases (CMMID) is "Animal Model of Diseases." The faculty specializes in using various animal models that include not only traditional laboratory animal models (mice and rats), but also non-traditional (chickens, pigs, dogs, fish, crab, equine) animal models. CMMID employs animal models to better understand the disease processes that impact both humans and domesticated species. The center is geared toward addressing current problems in public health that require the use of appropriate animal and tissue culture models, as well as gene-expression analysis.
This new act stipulated that 1) experiments must be proven absolutely necessary for instruction, or to save or prolong human life; 2) animals must be properly anesthetized; and 3) animals must be killed as soon as the experiment is over. Today, these three principles are central to the laws and guidelines governing the use of animals and research. In the U.S., the Animal Welfare Act of 1970 (see also Laboratory Animal Welfare Act) set standards for animal use and care in research. This law is enforced by APHIS's Animal Care program.
Others have criticized the composition of IACUCs, asserting that the committees are predominantly made up of animal researchers and university representatives who may be biased against animal welfare concerns. Larry Carbone, a laboratory animal veterinarian, writes that, in his experience, IACUCs take their work very seriously regardless of the species involved, though the use of non-human primates always raises what he calls a "red flag of special concern".Carbone, p. 94. A study published in Science magazine in July 2001 confirmed the low reliability of IACUC reviews of animal experiments.
D. rerio is a common and useful scientific model organism for studies of vertebrate development and gene function. Its use as a laboratory animal was pioneered by the American molecular biologist George Streisinger and his colleagues at the University of Oregon in the 1970s and 1980s; Streisinger's zebrafish clones were among the earliest successful vertebrate clones created. Its importance has been consolidated by successful large-scale forward genetic screens (commonly referred to as the Tübingen/Boston screens). The fish has a dedicated online database of genetic, genomic, and developmental information, the Zebrafish Information Network (ZFIN).
To identify and quantify adrenaline release during stress, beginning in about 1919 Cannon exploited an ingenious experimental setup. He would surgically excise the nerves by supplying the heart of a laboratory animal such as a dog or cat. Then he would subject the animal to a stressor and record the heart rate response. With the nerves to the heart removed, he could deduce that if the heart rate increased in response to the perturbation, then the increase in heart rate must have resulted from the actions of a hormone.
Frankie Trull is an American science advocate and lobbyist. She is founder and president of the Foundation for Biomedical Research, a non-profit organization that educates the public about animal research in the quest for medical advancements, treatments and cures for both humans and animals. Trull is also president of the National Association for Biomedical Research (NABR), which aims to provide a unified voice for the scientific community on legislative and regulatory matters affecting humane laboratory animal research. Trull received her undergraduate degree from Boston University and her master's degree from Tufts University.
This unit is involved in assays for the determination of pathogenicity indices for avian viruses, the production of serum standards for diagnostic test methods, and research projects on disease pathogenesis. NCFAD primarily works with farm animals such as pigs, chickens and cattle in order to carry out its mandate. The Animal Care Unit consists of a veterinarian and laboratory animal technologists. This unit is devoted to the best possible care for the animals and ensures that all animal use meets or exceeds the guidelines established by the Canadian Council on Animal Care (CCAC).
The Laboratory Animal Resource Center (LARC) provides a variety of services including animal breeding (mice and rats), rederivation, Tg or Cas9-mediated gene KO/KI/CKO by microinjection, IVF for rescue and expansion, cryopreservation and resuscitation, and quality control of laboratory animals. LARC has a 1,600 m2 barrier system for animal breeding, holding and experimentation. LARC interacts closely with the Institutional Animal Care and Use Committee (IACUC) to satisfy guidelines for the care and use of animals in research. On April 12, 2018, LARC was approved by Zhejiang Provincial Department of Science and Technology Agency.
Animals frequently used for polyclonal antibody production include chickens, goats, guinea pigs, hamsters, horses, mice, rats, and sheep. However, the rabbit is the most commonly used laboratory animal for this purpose. Animal selection should be based upon: # the amount of antibody needed, # the relationship between the donor of the antigen and the recipient antibody producer (generally the more distant the phylogenetic relationship, the greater the potential for high titer antibody response) and # the necessary characteristics [e.g., class, subclass (isotype), complement fixing nature] of the antibodies to be made.
Notice the two streptococci at the top of the photo that appear to have no capsule. Quellung is the German word for "swelling" and describes the microscopic appearance of pneumococcal or other bacterial capsules after their polysaccharide antigen has combined with a specific antibody. The antibody usually comes from a bit of serum taken from an immunized laboratory animal. As a result of this combination, and precipitation of the large, complex molecule formed, the capsule appears to swell, because of increased surface tension, and its outlines become clearly demarcated.
In August 1974, Lee and Goodman were arrested for taking part in a raid on Oxford Laboratory Animal Colonies in Bicester, earning them the moniker the "Bicester Two." Daily demonstrations took place outside the court during their trial; Lee's local Labour MP, Ivor Clemitson, was one of their supporters. They were sentenced to three years in prison, during which Lee went on the movement's first hunger strike to obtain vegan food and clothing. They were paroled after 12 months, Lee emerging in the spring of 1976 more militant than ever.
The Element-A is an Internet of Things (IoT) sensor that measures temperature, pressure, humidity and light simultaneously and transmits these readings via Bluetooth to the Gateway. The Element-A is typically used to monitor environments and micro-environments. Typical uses would include monitoring parts of a laboratory, animal research facilities or incubators. An article in The Scientist demonstrated how an HVAC system blowing on an HPLC instrument was causing erratic readings and the customer was able to discover this error using an Element-A to monitor the environment.
One of the most popular tropical aquarium fish, the green swordtail has been bred into various hybrid forms for the aquarium hobby due to its hardiness and suitability for community tanks. X. hellerii is a common laboratory animal and has been used as a model organism in studies involving female mate preference and male conflict. It is often designated X. helleri (with one 'i'), but authorities consider this an orthographic error and the spelling with two 'i's to be the valid specific epithet. It is named after Karl Bartholomaeus Heller, who collected the type specimen.
However they do exhibit sleep cycles with phases of REM-like electrical activity measurable by EEG. A recent study found periodic eye movements in the central bearded dragon of Australia, leading its authors to speculate that the common ancestor of amniotes may therefore have manifested some precursor to REMS. Sleep deprivation experiments on non-human animals can be set up differently than those on humans. The "flower pot" method involves placing a laboratory animal above water on a platform so small that it falls off upon losing muscle tone.
Nonetheless, this does not mean that they are not capable of grieving as some may present other reactions. This assumption raises issues and debates about ethics and welfare of animals in situations such as with laboratory animal management. William Russel and Rex Burch published the seminal book, The Principles of Humane Experimental Techniques, and introduced the now referred "3Rs" principles: reduction, refinement and replacement of animal use. Despite the attention brought to this issue by the authors and since, the number of animals used in research and testing continues to increase drastically.
Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States. Most research involving laboratory animals is funded by the United States National Institutes of Health or, to lesser extents, other federal agencies. The NIH Office of Laboratory Animal Welfare (OLAW) has been directed by law to develop policies that describe the role of Institutional Animal Care and Use Committees. Every institution that uses certain animals for federally funded laboratory research must have an Institutional Animal Care and Use Committee (IACUC).
NIN offers advanced education courses and MS-MD-PhD program(s) for nutrition, biochemistry, dietetics and laboratory animal sciences. The Centre is recognized by Dr. N.T.R. University of Health Sciences and Kaloji Narayana Rao University of Health Sciences for pursuing post graduation in Applied Nutrition. Recently NIN has started awarding Research Fellowships to the toppers in the MSc course to pursue PhD in the institution. The institute is well recognized by Osmania University, University of Hyderabad, Jawaharlal Nehru Technological University, for pursuing PhD in various streams of Life Sciences especially Biochemistry and Nutrition.
A humane endpoint can be defined as the point at which pain and/or distress is terminated, minimized or reduced for an entity in a trial (such as an experimental animal), by taking action such as killing the animal humanely, terminating a painful procedure, or giving treatment to relieve pain and/or distress.Humane Endpoints From Netherlands Association for Laboratory Animal Science (NVP). Retrieved April 2011. The occurrence of an individual in a trial having reached may necessitate withdrawal from the trial before the target outcome of interest has been fully reached.
Arguello's early research was focused on understanding cancer metastases. His investigations led to the development of laboratory animal models to develop and study experimental metastases to the bones and other organs. Using this model, he studied and described the sequence of events that take place during bone metastasis, particularly vertebral metastasis and spinal cord compression. Arguello and colleagues at the University of Rochester also established that both vascular access of cancer cells to a target organ and the tissue microenvironment in it played a critical role in the establishment of metastases.
The sanctuary also hosts veterinary, behavioral, animal care and organizational development interns throughout the year. Chimp Haven operates under strict standards of care that were especially created for the National Chimpanzee Sanctuary by the National Institutes of Health. Chimp Haven is the only sanctuary accredited by the American Association for Laboratory Animal Care (AALAC). Many of the sanctuary’s best practices have been adopted by other sanctuaries and zoological facilities. In 2016, Chimp Haven received a grant from New Mexico Community Foundation’s Chimpanzee Sanctuary Fund, a fundraising effort by Animal Protection of New Mexico and The Humane Society of the United States (HSUS).
In the night, Tess realizes that the only way to save her son is to destroy the base with all the proof and kill herself in the process. Amazed at how Liz didn't vote against her, Tess asks for Liz's help, trusting only her in the group. She understands her mistakes and she tells Liz that Max always loved only her and all the times that she and Max were together she always got flashes of Liz in his mind. Liz appreciates her sincerity and Tess asks Liz to not let the FBI study her like a laboratory animal.
Diabetes is a monthly peer-reviewed medical journal published since 1952 by the American Diabetes Association. It covers research about the physiology and pathophysiology of diabetes mellitus including any aspect of laboratory, animal or human research. Emphasis is on investigative reports focusing on areas such as the pathogenesis of diabetes and its complications, normal and pathologic pancreatic islet function and intermediary metabolism, pharmacological mechanisms of drug and hormone action, and biochemical and molecular aspects of normal and abnormal biological processes. Diabetes also publishes abstracts presented at the ADA's annual meeting, Scientific Sessions, in as a supplement.
The CompTox Chemicals Dashboard database contains high quality chemical structures and information that have been extensively curated and quality checked, which can be used as a resource for analytical scientists involved in structure identification. ToxCast bioactivity data view for Bisphenol A Chemical hazard data in the dashboard comes from both traditional laboratory animal studies and high-throughput screening. Biological data from high-throughput screening is generated by EPA's ToxCast program, the ToxCast data in the database provides information about the assays used and their response potency and efficacy. These data can be found in the bioactivity tab.
Aplysia californica has become a valuable laboratory animal, used in studies of the neurobiology of learning and memory, and is especially associated with the work of Nobel Laureate Eric Kandel. Its ubiquity in synaptic plasticity studies can be attributed to its simple nervous system, consisting of just 20,000 large, easily identified neurons with cell bodies up to 1 mm in size. Despite its seemingly simple nervous system, however, Aplysia californica is capable of a variety of non-associative and associative learning tasks, including sensitization, habituation, and classical and operant conditioning. Study typically involves a reduced preparation of the gill and siphon withdrawal reflex.
Bulik has been involved in the research and treatment of individuals with eating disorders since 1982. She received her BA from the University of Notre Dame and her MA and PhD in clinical psychology from the University of California, Berkeley. She completed internships and post-doctoral fellowships at the Western Psychiatric Institute and Clinic in Pittsburgh, PA. Bulik has developed outpatient, partial hospitalization, and inpatient services for eating disorders both in New Zealand and in the United States. Her research includes treatment, laboratory, animal, epidemiological, twin, and molecular genetic studies of eating disorders and body weight regulation.
The history of IACUCs evolved from the history of regulation of animal welfare in the USA. Prior to 1963, regulation was conducted solely by investigators, and research laboratories had inconsistent animal care policies and standards of care. A group of veterinarians formed the Animal Care Panel and began work in 1961, and in 1963 they published the first edition of The Guide for the Care and Use of Laboratory Animals, referred to hereafter as the Guide. Subsequent editions of the Guide were supported by NIH and published by the Institute of Laboratory Animal Research branch of the National Academy of Science.
SABRE Research UK is a British charity raising awareness of the need to remove bias from the conduct and scientific evaluation of animal research. DEBATE It addresses this issue by calling for systematic reviews of existing animal studies (published results of laboratory animal experiments). The charity was constituted in 2005 in response to disquiet about uninformed opinions about the scientific value of animal studies and dissatisfaction with 'polarised positions in the debate about animal research'. The charity found that neither the proponents of animal research nor its opponents were able to produce sufficiently sound scientific evidence in support of their opposing cases.
Major airlines such as Air China and China Eastern Airlines have also joined in on the global challenge of stopping laboratory tests on animals like primates and rodents. China's entry in the World Trade Organization could also be stymied if adequate progress is not made towards pressuring Chinese laboratories to follow international regulations for laboratory animal welfare. China has also felt domestic pressures to give laboratory animals more protection. In 2007, a photo taken by Li Feng depicting captive primates in cages waiting to be tested on won prizes in the economy and science categories in the China International Press Photo Contest.
While mice have proven to be a useful rodent model and techniques have been developed for routine disruption of their genes, in many circumstances rats are considered a superior laboratory animal for studying and modeling human disease. Rats are physiologically more similar to humans than are mice. For example, rats have a heart rate more similar to that of humans, while mice have a heart rate five to ten times as fast. It is widely believed that the rat is a better model than the mouse for human cardiovascular disease, diabetes, arthritis, and many autoimmune, neurological, behavioral, and addiction disorders.
The program is listed as an accredited institution by the Association for the Accreditation of Animal Laboratory Animal Care (AAALAC), whose voluntary accreditation program requires research programs to demonstrate that they meet standards of animal care beyond those required by law. As a standard targeted at laboratory animals, this accreditation requires a specific standard of general animal care, but does not set restrictions on the purposes for which the animals are used. The NMMP is also listed as a member of the Alliance of Marine Mammal Parks and Aquariums. The NMMP protocols for both care and research must be approved by an institutional animal care and use committee (IACUC).
The designations represent two streams rather than levels. The RLAT is employed by an animal facility, they have an animal science education, training in the care and use of laboratory animals and on the job practical experience. Continued development of this expertise enables him/her to obtain the knowledge base and practical competency required to meet the high standards set by the CALAS Registry examinations RLAT(R): Registered Laboratory Animal Technician (Research) The RLAT(R) typically works for one researcher as opposed to being employed by an animal facility. This person is very focused in one area of research and usually works with only one or two species of animals.
In laboratory animal husbandry, there is a huge demand for animals that have been kept in disease free conditions and housed in barrier units such as Individually Ventilated Cages. This is very important because when animals are used for scientific research, particularly drug-related research, the animals must provide accurate and valid results. Using an animal that is ill may cause the severity limit to be exceeded. If the animal already has a disease and then undergoes experimentation of a substance that also produces effects on the animals health, it could potentially worsen the effects of the agent being tested causing the animal to experience more suffering than necessary.
Laboratory animals are not restricted to rats, mice, dogs, and rabbits, but also include fish, frogs and birds. Research into alternatives to replace these species is often neglected, although fish are the third most widely used laboratory animal used for scientific purposes in the EU. This is also the field where until now only two alternative tests exist worldwide: One guideline, OECD TG 236, and one guidance (OECD series on testing and assessment 126) are so far available. Euroecotox is a European network for alternative testing strategies in ecotoxicology. It was funded by the Seventh Framework Programme (FP7) of the European Commission Environment Programme.
The Animal Welfare Act (Laboratory Animal Welfare Act of 1966, ) was signed into law by President Lyndon B. Johnson on August 24, 1966. It is the main federal law in the United States that regulates the treatment of animals in research and exhibition. Other laws, policies, and guidelines may include additional species coverage or specifications for animal care and use, but all refer to the Animal Welfare Act (otherwise known as the "AWA") as the minimally acceptable standard for animal treatment and care. The USDA and APHIS oversee the AWA and the House and Senate Agriculture Committees have primary legislative jurisdiction over the Act.
Most vets work in clinical settings, treating animals directly. These vets may be involved in a general practice, treating animals of all types; may be specialized in a specific group of animals such as companion animals, livestock, laboratory animals, zoo animals or horses; or may specialize in a narrow medical discipline such as surgery, dermatology, laboratory animal medicine, or internal medicine. As with healthcare professionals, vets face ethical decisions about the care of their patients. Current debates within the profession include the ethics of purely cosmetic procedures on animals, such as declawing of cats, docking of tails, cropping of ears and debarking on dogs.
The National Biotechnology Research Park, finished in 2017 and inaugurated in October 2018 by Taiwanese President Tsai Ing-wen, is located about 500 m north of the main campus and 500 m south of the Nankang Software Park, with the Nangang station to the west and the Taipei Nangang Exhibition Center MRT station to the east. It is home to four Academia Sinica centers for translational medicine, innovation, incubation, and bioinformatics service, as well as the Biotechnology Development Center of the Ministry of Economic Affairs, the Food and Drug Administration of the Ministry of Health and Welfare, and the National Laboratory Animal Center of the Ministry of Science and Technology.
The work environment has played a significant role in the occurrence of adverse human health effects due to chemical and biological hazards for centuries. Occupational health specialists, including toxicologists, rely upon human and animal data to determine safe exposure levels. If effects observed in workers can be reproduced in a laboratory animal, it becomes possible to investigate the mechanisms that might reasonably be expected to produce such effects. On the other hand, shedding light on the mechanism by which a designated effect is produced in a test animal species may make it easier to find ways to prevent such effects from occurring in humans.
A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. They are important animal models for studying the role of genes which have been sequenced but whose functions have not been determined. By causing a specific gene to be inactive in the mouse, and observing any differences from normal behaviour or physiology, researchers can infer its probable function. Mice are currently the laboratory animal species most closely related to humans for which the knockout technique can easily be applied.
Experiments on vertebrate animals in the European Union are since January 1, 2013. subject to Directive 2010/63/EU on the protection of animals used for scientific purposes, which was finalized in November 2010 and updated and replaced the Directive 86/609/EEC on the protection of Animals used for Experimental and other scientific purposes, adopted in 1986."Directive 86/609/EEC on the protection of Animals used for Experimental and other scientific purposes" European Commission, 1986. Retrieved February 8, 2007 Directive 86/609/EEC showed considerable variation in the manner member countries chose to exercise the directive: compare, for example, legislation from Sweden,"Laboratory animal research legislation in Sweden" , EBRA.
The Virginia–Maryland College of Veterinary Medicine (also known as the Virginia–Maryland Regional College of Veterinary Medicine) is a state- supported college of two states, Virginia and Maryland, filling the need for veterinary medicine education in both states. Students from both states are considered "in-state" students for admissions purposes. It is one of 28 colleges of veterinary medicine in the United States and is accredited by the American Veterinary Medical Association's Council on Education and the Association for Assessment and Accreditation of Laboratory Animal Care International. In 2011, the U.S. News 'Veterinary Medicine' Ranking placed the college tied for 17th with Iowa State University in a poll of 25 ranked schools.
Pregnancy testing was conducted in the mid-20th century by injecting urine from a woman into a male toad's lymph sacs, and if spermatozoa appeared in the toad's urine, the patient was deemed to be pregnant. The tests using toads were faster than those employing mammals; the toads were easier to raise, and, although the initial 1948 discovery employed Bufo arenarum for the tests, it soon became clear that a variety of anuran species were suitable, including the cane toad. As a result, toads were employed in this task for around 20 years. As a laboratory animal, the cane toad is regarded as ideal; they are plentiful, and easy and inexpensive to maintain and handle.
In 1986, MSPCA-Angell launched the statewide subsidized Spay/Neuter Assistance Program (SNAP) for low income pet owners who qualify. The MSPCA formed the Center for Laboratory Animal Welfare (CLAW) in 1992 and, in the following year, established the Animal Disaster Relief Fund to aid in animal protection and rescue globally. In 1994, a new MSPCA facility was opened in Brockton, Massachusetts, and Nevins Farm in Methuen launched the Equine Ambulance Program to offer emergency rescue and transport of disabled horses in New England and ambulance services events involving horses worldwide. In 1994, the society established Phinney's Friends, the first program run by a humane society to assist people with HIV/AIDS and their pets.
In 2013, a jury in Maine found that Jackson Laboratory did not violate that state's whistleblower protection law when they fired an employee who claimed to have been terminated after reporting her concerns about the treatment of animals to the National Institutes of Health Office for Laboratory Animal Welfare. The worker accused the laboratory of “allowing mice to suffer and then die in their cages instead of euthanizing them” and of cutting off the toes of mice to identify them. Jackson laboratory denied the allegations and said the worker was fired for her confrontational demeanor. In 2009, Jackson Laboratory was fined $161,680 by the EPA for improperly handling and storing hazardous materials.
Located in North Grafton, Massachusetts, the Cummings School offers a four-year curriculum leading to the degree of Doctor of Veterinary Medicine. The School also offers MS degrees in Animals and Public Policy and in Conservation Medicine, a PhD in Comparative Biomedical Sciences, as well as combined DVM/MS degree programs in Comparative Biomedical Studies and Laboratory Animal Medicine. The DVM/MPH degree program is conducted in collaboration with the Tufts University School of Medicine, as well as the DVM/MS program with the Fletcher School of Law and Diplomacy, the DVM/MS in Applied Biotechnology with Worcester Polytechnic Institute, the DVM/PhD with Sackler School of Graduate Biomedical Sciences, and the DVM/PhD with the University of Massachusetts Medical School.
A Designated Member Review (DMR) or Designated Subcommittee Review (DSR) is a review of a protocol where a committee designates one or more members of the committee to review a decisionmaking process or a protocol or procedure, a review which would ordinarily require the full committee's review. Typically this pertains to IACUCs. In protocols of the National Institutes of Health (NIH) in the United States, 'Correct Conduct of Full-Committee and Designated- Member Protocol Reviews', there are two ways a procedure or protocol can be reviewed, according to PHS policy.DMR & FCR, Office of Laboratory Animal Welfare - Topic Index, Protocol Review Sometimes a protocol or amendment to policies is submitted, which may not need to be considered at a full meeting.
While the bulk of LLW is not highly radioactive, the definition of LLW does not include references to its activity, and some LLW may be quite radioactive, as in the case of radioactive sources used in industry and medicine. LLW includes items that have become contaminated with radioactive material or have become radioactive through exposure to neutron radiation. This waste typically consists of contaminated protective shoe covers and clothing, wiping rags, mops, filters, reactor water treatment residues, equipments and tools, luminous dials, medical tubes, swabs, injection needles, syringes, and laboratory animal carcasses and tissues. The radioactivity can range from just above background levels found in nature to very highly radioactive in certain cases such as parts from inside the reactor vessel in a nuclear power plant.
In 1961, HSUS investigator Frank McMahon launched a probe of dog dealers around the country to generate support for a federal law to prevent cruelty to animals destined for use in laboratories. The five-year investigation into the multilayered trade in dogs paid off in February 1966 when Life published a photo-essay of a raid conducted on a Maryland dog dealer's premises by McMahon and the state police. The Life spread sparked outrage, and tens of thousands of Americans wrote to their congressional representatives, demanding action to protect animals and prevent pet theft. That summer the U.S. Congress approved the Laboratory Animal Welfare Act (later renamed the "Animal Welfare Act of 1966"), only the second major federal humane law passed since World War II.
Class B dealers , Humane Society of the United States."Who's Who of Federal Oversight of Animal Issues" , Aesop Project.Salinger, Lawrence and Teddlie, Patricia. "Stealing Pets for Research and Profit: The Enforcement (?) of the Animal Welfare Act" , paper presented at the annual meeting of the American Society of Criminology, Royal York, Toronto, 15 October 2006Reitman, Judith (1995) Stolen for Profit, Zebra, .Moran, Julio (12 September 1991) "Three Sentenced to Prison for Stealing Pets for Research," L.A. Times. It was in part out of public concern over the sale of pets to research facilities that the 1966 Laboratory Animal Welfare Act was ushered in—the Senate Committee on Commerce reported in 1966 that stolen pets had been retrieved from Veterans Administration facilities, the Mayo Institute, the University of Pennsylvania, Stanford University, and Harvard and Yale Medical Schools.
Animal technology refers to the practices of keeping, breeding and providing care for animals that are used for scientific purposes, such as captive in a laboratory. Animal technology is one of the recognized professional areas held by registered science technicians, and animal technologists, also called animal technicians, play a key role in supporting biomedical research by ensuring that animals are available for study. Principal areas of animal technology include animal husbandry and breeding, providing day-to-day care for laboratory animals, ensuring compliance with animal welfare practices and legal issues and performing essential scientific procedures. Technical qualifications for animal technologists and the regulations they must adhere to vary by country, but in many parts of the world animal technology is a highly structured profession that forms part of laboratory management.
During this time, he also published in the Journal of Value Inquiry, Philosophy in the Contemporary World, and the Journal of Applied Philosophy, as well as working as a lecturer in the USYD philosophy department and a guest lecturer for the USYD Laboratory Animal Services. After his PhD, Hadley worked as a lecturer in communication ethics in the Charles Sturt University (CSU) School of Communication and a lecturer in philosophy at the CSU School of Humanities and Social Sciences. He then joined the University of Western Sydney School of Humanities and Communication Arts, first as a lecturer in philosophy, and then as a senior lecturer in philosophy. Animal Ethics and Philosophy: Questioning the Orthodoxy, a collection edited by Hadley with the Finnish philosopher Elisa Aaltola, was published in 2015 by Rowman & Littlefield International.
Overall, this movement had no US legislative success. The passing of the Laboratory Animal Welfare Act, in 1966 was more focused on protecting the welfare of animals that are used in all fields, including research, food production, consumer product development, etc.Buettinger, Craig Antivivisection and the charge of zoophil-psychosis in the early twentieth century. The Historian 1993 On the other side of the debate, those in favor of animal testing held that experiments on animals were necessary to advance medical and biological knowledge and to ensure the safety of products intended for human and animal use. In 1831, the founders of the Dublin Zoo—the fourth oldest zoo in Europe, after Vienna, Paris, and London—were members of the medical profession, interested in studying the animals both while they were alive and when they were dead.
Sommer (2008) classified historical accounts related to vitamin A and/or manifestations of deficiency as follows: "ancient" accounts; 18th- to 19th-century clinical descriptions (and their purported etiologic associations); early 20th-century laboratory animal experiments, and clinical and epidemiologic observations that identified the existence of this unique nutrient and manifestations of its deficiency. During World War II, German bomber aircraft attacked Britain at night rather than by day to avoid detection, but British interceptor aircraft used the Airborne Intercept Radar system, developed in 1939, to locate bombers they could not see. To keep AI secret from the German military, the Ministry of Information told newspapers that the good night-time performance of Royal Air Force pilots was due to a high dietary intake of carrots rich in vitamin A, propagating the myth that carrots enable people to see better in the dark.
They can be recognised by the wearing of epaulettes bearing a lamb, representing the patients they care for; a lamp, representing knowledge; and an axe, symbolising strength. They are represented by the Veterinary Nurses Association of South Africa (VNASA) which was started in 1978 after South Africa's first class of qualified veterinary nurses graduated. Permission to offer a Bachelor of Veterinary Nursing through the University of Pretoria was recently applied for to the South African Qualifications Authority; under consideration is the addition of one year of study to the current DipVetNurs program, converting the diploma to a degree. Other veterinary para- professionals found in South Africa include animal health technicians (who oversee the well-being of food animals), laboratory animal technologists (who oversee the well-being of research animals), and veterinary technologists (who work mainly in diagnostic laboratories).
In the United States, animal testing on vertebrates is primarily regulated by the Animal Welfare Act of 1966 (AWA), and the Animal Welfare Regulations which is enforced by the Animal Care divisionAnimal Care USDA Animal and Plant Health Inspection Service, Accessed 06 September 2007 of the Animal and Plant Health Inspection Service (APHIS) of the United States Department of Agriculture (USDA). The AWA contains provisions to ensure that individuals of covered species used in research receive a certain standard of care and treatment, provided that the standard of care and treatment does not interfere with "the design, outlines, or guidelines of actual research or experimentation.""Appendix C: Some Federal Laws Relevant to Animal Care and Use", Guide for the Care and Use of Laboratory Animals (1996), Institute for Laboratory Animal Research. Currently, AWA only protects mammals.
The National Institute of Nutrition (NIN) is an Indian Public health, Nutrition and Translational research center located in Hyderabad, India. The institute is one of the oldest research centers in India, and the largest center, under the Indian Council of Medical Research, located in the vicinity of Osmania University. The institute has associated clinical and pediatric nutrition research wards at various hospitals such as the Niloufer Hospital for Women and Children, the Government Maternity Hospital, the Gandhi Medical College and the Osmania General Hospital in Hyderabad. The National Centre for Laboratory Animal Science (to be integrated into the National Animal Resource Facility for Biomedical Research), the Food and Drug Toxicology Research Centre, the National Nutrition Monitoring Bureau are the other wings of NIN, ICMR's Institutes/Centres (scroll down page to find NIN) for India's Ministry of Health and Family Welfare.
Beginning in 1993, Grieder joined the faculty and conducted research at the medical school of the Uniformed Services University of the Health Sciences (USU) within the Department of Microbiology and Immunology, and Molecular/Cell Biology and Neuroscience in Bethesda, Maryland. Her areas of expertise include viral-induced neuroimmunology and neurodegeneration, emerging viral threats and the molecular genetics of the VEE virus. In 2000, at the National Center for Research Resources (NCRR), Grieder began managing the Division of Comparative Medicine's Laboratory Animal Sciences Program, where she created the Mutant Mouse Regional Resource Centers Program and supervised grants related to mammalian models, comparative and functional genomics, and training opportunities for veterinarians and veterinary students. Grieder joined the National Institutes of Health (NIH) in 2000 as a program official in the Division of Comparative Medicine, which was located in the former National Center for Research Resources (NCRR).
The author attempts to lessen the confusion > surrounding this issue by describing these methods, along with examples of > faulty hybrids and convenient strategies to bring unacceptable methods into > compliance. Although the United States Public Health Service Policy on > Humane Care and Use of Laboratory Animals (PHS Policy)1 has existed since > 1986 and the United States Department of Agriculture’s (USDA) Animal Welfare > Act2 regulations governing Institutional Animal Care and Use Committees > (IACUCs) have been extant since 1989, continuing questions and > misunderstandings exist regarding the procedures used for protocol review. Contrasted with 'Full Committee Review' (FCR).Office of Laboratory Animal Welfare (OLAW), , Office of Extramural Research, Notice Number: NOT-OD-09-035, IACUC Actions Following Full Committee Review (FCR) Declining a DMR Request A request for a DMR can be declined by one or more IACUC members on the basis of reliability - that a DMR would compromise the reliability of the committee's conduct of its duties.
A tabby cat and a mixed Molosser dog A pet, or companion animal, is an animal kept primarily for a person's company or entertainment rather than as a working animal, livestock or a laboratory animal. Popular pets are often considered to have attractive appearances, intelligence and relatable personalities, but some pets may be taken in on an altruistic basis (such as a stray animal) and accepted by the owner regardless of these characteristics. Two of the most popular pets are dogs and cats; the technical term for a cat lover is an ailurophile and a dog lover a cynophile. Other animals commonly kept include: rabbits; ferrets; pigs; rodents, such as gerbils, hamsters, chinchillas, rats, mice, and guinea pigs; avian pets, such as parrots, passerines and fowls; reptile pets, such as turtles, alligators, crocodiles, lizards, and snakes; aquatic pets, such as fish, freshwater and saltwater snails, amphibians like frogs and salamanders; and arthropod pets, such as tarantulas and hermit crabs.
Albert Szent-Györgyi wrote that he won a Nobel Prize after he found a way to mass-produce vitamin C for research purposes when he lived in Szeged, which had become the center of the paprika (red pepper) industry. Vitamin C was discovered in 1912, isolated in 1928 and synthesized in 1933, making it the first vitamin to be synthesized. Shortly thereafter Tadeus Reichstein succeeded in synthesizing the vitamin in bulk by what is now called the Reichstein process. This made possible the inexpensive mass-production of vitamin C. In 1934 Hoffmann–La Roche trademarked synthetic vitamin C under the brand name Redoxon and began to market it as a dietary supplement. In 1907 a laboratory animal model which would help to identify the antiscorbutic factor was discovered by the Norwegian physicians Axel Holst and Theodor Frølich, who when studying shipboard beriberi, fed guinea pigs their test diet of grains and flour and were surprised when scurvy resulted instead of beriberi.
OLAW oversees all animal studies funded by the Public Health Service (including NIH). The Health Research Extension Act of 1985 directed the NIH to write the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals. This Policy applies to any individual scientist or institution in receipt of federal funds and requires each institution to have an IACUC, among other stipulations. OLAW enforces the recommendations in the Guide for the Care and Use of Laboratory AnimalsGuide for the Care and Use of Laboratory Animals: Eighth Edition published by the Institute for Laboratory Animal Research,Page Not Found : Division on Earth and Life Studies which covers all vertebrate species, including rodents, birds, fish, amphibians, and reptiles Guide for the Care and Use of Laboratory Animals: Eighth Edition This means that IACUCs oversee the use of all vertebrate species in research at facilities receiving federal funds, even if the species are not covered by the AWA.
An investigation was conducted by 18 veterinarians from the American College of Laboratory Animal Medicine, commissioned by the Office for Protection from Research Risks (OPRR). Charles R. McCarthy, director of the OPRR at the time, wrote that "[d]espite the fact that Unnecessary Fuss grossly overstated the deficiencies in the Head Injury Clinic, OPRR found many extraordinarily serious violations of the Guide for Care and Use of Laboratory Animals ... Furthermore, OPRR found deficiencies in the procedures for care of animals in many other laboratories operated under the auspices of the university." The violations included that the depth of anesthetic coma was questionable; that most of the animals were not seen by a veterinarian either before or after surgery; survival surgical techniques were not carried out in the required aseptic manner; that the operating theater was not properly cleaned; and that smoking was allowed in the operating theater despite the presence of oxygen tanks. When PETA made its 26-minute film available, the OPRR initially refused to investigate because the film had been edited from 60 hours of videotape.
Palmiter's valuable research has contributed greatly to the molecular biology field; therefore, he has received numerous awards and accolades as well as given lectures at notable conferences throughout his career. His lectures include the Vern Chapman lecture in 2004 at the 18th International Mouse Genome Meeting as well as the Wallace Rowe lecture in 1999 at the American Association of Laboratory Animal Sciences 50th Annual Meeting. In 1999 he became a Tyner Eminent Scholar at Florida State University, in 1998 he was distinguished as a Second International Fellow of the Garvan Institute in Sydney, Australia, and in 1988 he was elected to both the National Academy of Sciences and the American Academy of Arts and Sciences. His awards include the Charles-Leopold Mayer Award from the French Academy of Sciences in 1994, the Distinguished Service Award from the US Department of Agriculture in 1989, the New York Academy Award in Biological and Medical Sciences in 1983, and the George Thorn Award from the Howard Hughes Medical Institute in 1982.
Shortly after training, Bono saw duty in Operations Desert Shield and Desert Storm as head, Casualty Receiving, Fleet Hospital Five in Saudi Arabia from August 1990 to March 1991. Upon returning, she was stationed at Naval Medical Center Portsmouth as a surgeon in the General Surgery department; surgical intensivist in the Medical/Surgical Intensive Care Unit, and attending surgeon at the Burn Trauma Unit at Sentara Norfolk General Hospital. Her various appointed duties included division head of Trauma; head of the Ambulatory Procedures Department (APD); chair of the Laboratory Animal Care and Use Committee; assistant head of the Clinical Investigations and Research department; chair of the Medical Records Committee, and Command Intern Coordinator. She has also served as the Specialty Leader for Intern Matters to the Surgeon General of the Navy. In September 1999, she was assigned as the director of Restorative Care at the National Naval Medical Center in Bethesda, Maryland, followed by assignment to the Bureau of Medicine and Surgery from September 2001 to December 2002 as the medical corps career planning officer for the Chief of the Medical Corps.
If everyone on the committee agrees, then the Chair or the committee can assign a person of knowledge and selected other member(s) to review the protocol and approve it or send it back to the full committee for discussion. A first step in such a process is for the chair to poll committee members to determine agreement for the DMR. If they agree, the DMR proceeds; if they do not agree, the DMR does not occur and it should be considered at a convened meeting by the complete committee.Office of Laboratory Animal Welfare - Topic Index, Protocol Review"Protocol review ... How is your IACUC doing?", AAALAC International Connection, Winter/Spring 2001Guide for the Care and Use of Laboratory Animals (8th Edition, NRC 2011, National Academies Press), available for free download as a PDF in English, Chinese, Japanese, and Thai, and available as a hard copy > The United States Public Health Service on Humane Care and Use of Laboratory > Animals (PHS Policy, Reprinted October 2000), states that prior to review, > each member of the IACUC must be given a list of proposed research projects > to be considered.

No results under this filter, show 180 sentences.

Copyright © 2024 RandomSentenceGen.com All rights reserved.