Another 34% had success when trying intrauterine insemination (IUI) first.
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My first fertility treatment, IUI (intrauterine insemination), was 6 years ago.
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I've had friends try intrauterine insemination when they've struggled to conceive.
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I started with intrauterine insemination (IUI), the baby step of fertility intervention.
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Her doctor prescribed clomid, an oral medicine to stimulate ovulation, and she tried intrauterine insemination.
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"Intrauterine insemination (IUI) — a type of artificial insemination — is a procedure for treating infertility," according to Mayo Clinic.
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In the first 4½ years of their marriage, she miscarried four times and made three intrauterine insemination attempts without success.
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After three failed attempts at intrauterine insemination, or IUI, and a failed egg retrieval, they are trying IUI yet again.
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After seeking the help of a reproductive endocrinologist, the couple tried in vitro fertilization treatment when IUI (intrauterine insemination) didn't work.
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If the allergy is severe enough that a person can't tolerate the semen, intrauterine insemination or IVF can be an option.
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She and her husband had tried intrauterine insemination three times without success before moving on to two failed rounds of IVF.
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It is great that assisted reproductive technology, such as IVF or IUI (intrauterine insemination), gives women options and potential for childbearing.
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The day before my first intrauterine insemination, my husband and I had the usual gang over to watch Game of Thrones.
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However, Emily, 25, was unable to conceive naturally and was also unable to get pregnant when the couple tried intrauterine insemination (IUI).
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Compared to intrauterine insemination, or IUI (in which sperm is placed inside a person's uterus), IVF is a much more invasive procedure.
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If you have a semen allergy and want to conceive, your doctor may suggest in vitro fertilization (IVF) or intrauterine insemination (IUI).
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That's fine if you're trying to get pregnant without resorting to expensive treatments like intrauterine insemination (IUI) or in vitro fertilization (IVF).
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They then tried intrauterine insemination, a fertility treatment in which sperm is placed directly inside a woman's uterus -- and the procedure worked.
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L is more cautious, almost as if she has read Katkin's story, advising fewer drugs after a failed attempt at intrauterine insemination.
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One intrauterine insemination, which we tried before I.V.F., was canceled when the most reputable clinic in Kabul forgot to order a catheter.
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We found a donor, did four rounds of IUI (intrauterine insemination, which is less invasive) and one round of IVF (in-vitro fertilization).
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Polaris can forecast how likely a couple is to get pregnant using different treatment methods—intrauterine insemination versus in-vitro fertilization, for example.
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In the meantime, she was willing to prescribe letrozole, a medication used to promote ovulation, or, if that failed, a course of intrauterine insemination.
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Many women choose intrauterine insemination (ICI), wherein a medical professional inserts a catheter past the cervix so the sperm is introduced directly into the uterus.
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"We did the exact same thing we did with our first daughter, Blayke (who's 5): intrauterine insemination, "Adam says in the latest issue of PEOPLE.
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Soon after her 40th birthday, still not having pinpointed the love of her life, she became pregnant by intrauterine insemination and had a son, Alexander.
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After three intrauterine insemination procedures, three rounds of I.V.F., and two years on an adoption agency's waiting list, I still long to become a mother.
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Renee and Anna McInarnay both welcomed baby girls just two days apart after the Mississippi couple became pregnant at the same time through intrauterine insemination (IUI).
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As far back as the 1940s, plenty of women have gotten pregnant via the low-tech intrauterine insemination (IUI)—aka "turkey baster" approach— no hormones or surgeries required.
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She said that since then, about 85,000 women had become pregnant in the tri-county area, including about 5,000 who might have used fertility methods like intrauterine insemination.
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She eventually got pregnant with Graham after three rounds of intrauterine insemination (IUI), a fertility treatment that entails the placement of the male partner's sperm in the woman's uterus.
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For the 12% of women like Kowalewski who struggle to conceive, procedures like IVF and intrauterine insemination (IUI) are emotionally arduous, physically taxing, incredibly stressful, and usually very expensive.
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She eventually got pregnant with Graham after three rounds of intrauterine insemination (IUI), a fertility treatment that entails the direct placement of the male partner's sperm in the woman's uterus.
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They've now looked into IVF, and the simpler option, IUI, or intrauterine insemination, where the sperm is implanted directly into the uterus to make it easier to reach an egg.
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When the chance of the woman getting pregnant on her own over the next 12 months was estimated to be less than 30 percent, the woman was also offered intrauterine insemination.
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But the company's sales could explode if plans tell their enrollees that they must first try The Conception Kit before the plan covers more-expensive fertility drugs, intrauterine insemination or IVF.
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After having "no luck" getting pregnant after the surgery, she and Julian, 36, did one unsuccessful round of intrauterine insemination in 2015, followed by two unsuccessful rounds of in vitro fertilization in 2016.
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Ponto told Us Weekly that she had to undergo five rounds of intrauterine insemination (IUI) – a method in which sperm is carefully placed into a uterus by a medical professional – before she conceived.
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In other words, employees have a certain amount allotted to spend on fertility treatments such as egg-freezing, IVF, intrauterine insemination (IUI) or something else with a doctor and facility of their choosing.
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She ran more tests to find out if my fallopian tubes were open and to check my thyroid levels, then told me her recommended course of action: IUI (Intrauterine Insemination) with fertility drugs.
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On that rainy winter morning two months ago, I was being monitored for my third and final IUI—or Intrauterine Insemination, which is when sperm is inserted directly into the uterus to facilitate fertility.
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A traditional surrogate becomes pregnant with her own egg and the father's sperm—via IVF or intrauterine insemination (in which sperm are placed directly in the uterus)—and she is the child's biological mother.
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Through IUI (intrauterine insemination) treatment, Clarissa was soon pregnant with Shanna and discovered at her 20-week ultrasound that her daughter had a rare heart defect caused by a rare chromosome condition called 22q11.
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Intrauterine insemination is on the cheaper end of available options, ranging from $247 to $236,240 per insemination, but the cost is generally higher when the patient requires donated sperm, as queer (and single) people necessarily do.
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"That was really difficult, and I ended up having to have a couple [dilation and curretage surgeries] after that," she recalled, revealing that she and Caldwell used intrauterine insemination (IUI), which worked on the third try.
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After five cycles of Clomid (two with timed intercourse and three with intrauterine insemination, in which my husband's sperm was manually inserted into my uterus with a catheter), I was no closer to motherhood than before.
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Headquartered in New York, the business has secured a $22014 million Series A investment from Regal Healthcare Capital Partners to expand its fertility services, which also include infertility treatments, such as in vitro and intrauterine insemination.
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In the emotional episode, Mellencamp Arroyave details the experience of undergoing intrauterine insemination to get pregnant with Slate — which, luckily, worked on the first try — before experiencing multiple failed rounds of in vitro fertilization and a miscarriage.
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The 29-year-old tells PEOPLE that it was months before she was healthy enough to try again — this time with intrauterine insemination (IUI), a fertility treatment that entails the placement of the male partner's sperm in the woman's uterus.
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Infertility services or medications used by some mothers in the study included oral or injectable medicines that stimulate ovulation, or ovulation induction plus intrauterine insemination, or so-called assisted reproductive technology, such as in vitro fertilization, frozen embryo transfer or donor eggs or embryos.
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Among women whose only infertility problem is the failure of their ovaries to release egg cells during the menstrual cycle, as many as 21 percent who take the medicine will typically ovulate and be able to conceive naturally or through intrauterine insemination or in vitro fertilization.
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The fitness trainer has been open about her struggles with infertility over the past year and a half, and after several months of trying to get pregnant through IUI, or intrauterine insemination, in which semen is inserted into the uterus, Victoria, 30, said that they had to stop.
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For the study, researchers examined data on two groups of infertile women with advanced endometriosis: 894 who tried to conceive with in vitro fertilization (IVF) or other types of assisted reproductive technology; and 1,358 who tried to conceive with non-ART methods like timed intercourse or intrauterine insemination.
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If I couldn't get pregnant via intrauterine insemination (IUI, essentially the turkey-baster method) and had to do in vitro fertilization (IVF, which is more in-depth and involves combining an egg with a sperm outside the body, then transferring it inside the body), it would be substantially more than I could afford.
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For women trying to get pregnant on their own, the most common fertility treatments are intrauterine insemination (IUI), a non-invasive procedure wherein donor sperm is placed in the uterus while a woman is ovulating, and in vitro fertilization (IVF), which involves removal and fertilization of a woman's eggs via donor sperm, followed by embryo transfer into her uterus.
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The clinic donated one attempt at intrauterine insemination a few months ago, but it failed, and the doctor told the couple that their best bet, probably their only one, was I.V.F. They cannot afford it, and are considering borrowing the money from a finance company that lends to couples having I.V.F. She is now 40, and time is running out.
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A sneak peek of Kindbody's "fertility bus," which is still in the works A sneak peek of Kindbody's "fertility bus," which is still in the works Kindbody, which has raised $22 million to date from Green D Ventures, Trail Mix Ventures, Winklevoss Capital, Chelsea Clinton, Clover Health co-founder Vivek Garipalli and others, also provides women support getting pregnant with in vitro fertilisation (IVF) and intrauterine insemination (IUI).
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This estimate is based on Progyny's internal data, company spokesperson Selena Yang tells CNBC Make It. According to Progyny, the typical "road to pregnancy" without coverage from Progyny involves an average of three intrauterine insemination (IUI) treatments (a procedure where a sperm is placed inside a woman's uterus, thereby increasing the chances of fertilization), the medications for those treatments, and two in vitro fertilization (IVF) cycles (where an embryo is implanted in the lining of the uterus), as well as the corresponding associated medications, Yang says.
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In non-tubal sub fertility, fallopian tube sperm perfusion may be the preferred technique over intrauterine insemination.
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The use of fertility medication that stimulates ovulation (clomiphene citrate, gonadotropins) combined with intrauterine insemination (IUI) enhances fertility in these patients as does assisted reproduction.
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Danielle was also placed on Clomid to help her produce eggs and ovulate regularly. They went through 5 cycles (5 months) of intrauterine insemination on Clomid before discussing in vitro fertilization as an option. Instead of in vitro fertilization, they opted to switch Danielle to Femara and attempted intrauterine insemination again, ultimately becoming pregnant with Blayke. During their second journey of infertility, Adam's testosterone levels, sperm count, and sperm motility were considered normal; thus no infertility treatment was necessary for Adam.
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The male's ejaculate may be centrifuged from urine voided, and the isolated sperm injected directly into the woman through the use of intrauterine insemination. In more severe cases, in-vitro fertilization with intracytoplasmic sperm injection may be used.
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Cervical stenosis may impact natural fertility by impeding the passage of sperm into the uterus. In the context of infertility treatments, cervical stenosis may complicate or prevent the use of intrauterine insemination (IUI) or in vitro fertilization (IVF) procedures.
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When a sperm sample is prepared for intrauterine insemination, it is washed at a facility such as a fertility clinic or a sperm bank. Some sperm does not survive the washing process, as is also the case when freezing the sperm.
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The ultrasonic wavelengths create an audio "image" as the machine therapeutically shows a baby growth inside the genetic mother's uterus. They serve as a monitor and have a validation of the predictions of ovulation and the IUI Intrauterine insemination cycles.
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Intrauterine insemination. Information notes from the fertility clinic at Aarhus University Hospital, Skejby. By PhD Ulrik Kesmodel et al. However, these pregnancy rates may be very misleading, since many factors have to be included to give a meaningful answer, e.g.
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Stage lives in Philadelphia with her wife and two children. She experienced infertility and underwent both intrauterine insemination, IVF, and a miscarriage before conceiving her daughter. She experienced depression and suicidal thoughts during pregnancy. Her wife, who also experienced infertility, carried their son.
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Their desire to start a family was impeded by infertility. It was discovered Ethan suffered an extremely low sperm count. They turned to fertility treatments, using a sperm donor along with intrauterine insemination (IUI). Their first daughter Eliot McKenna was born on July 14, 2004.
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Intrauterine insemination causes an evolutionary consequence resulting from polyandrous behavior. When multiple males mate with one female, there are multiple sets of sperm gametes in a female mouse. Offspring fertilized by multiple males can compete more strongly for mother's resources and can lead to a decrease in body size and variation in body size.
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Usual approaches include using the sperm for intrauterine insemination (IUI), in vitro fertilization (IVF), or IVF with intracytoplasmatic sperm injection (ICSI). With IVF-ICSI even with a few sperm pregnancies can be achieved. Obstructive causes of post-testicular infertility can be overcome with either surgery or IVF-ICSI. Ejaculatory factors may be treatable by medication, or by IUI therapy or IVF.
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However, Danielle was placed back on Femara to help with egg production and ovulation. On the fourth cycle of intrauterine insemination, Danielle became pregnant with the quintuplets. The quintuplets were born prematurely, at 28 weeks, and spent several months in the NICU. Ava was the last quintuplet to be released from the NICU due to a series of acid-reflux episodes.
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Treatment may include ovulation induction, surgical interventions, artificial insemination, such as intrauterine insemination (IUI), in vitro fertilization (IVF), or the use of an egg donor or a sperm donor. In vitro fertilization is the most well known of the assisted reproductive technology procedures performed at a fertility clinic. Advanced male infertility treatments such as TESA (Testicular Epididymal Sperm Aspiration) is also provided by fertility clinics these days.
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Sperm-bound antibodies are usually assessed >6 months after the vasectomy reversal if no pregnancy has ensued. Treatment options include steroid treatment, intrauterine insemination (IUI) and in vitro fertilization (IVF) techniques. #Occasionally, scar tissue develops at the site where the vas deferens is reconnected, causing a blockage. Depending on the physician, this occurs in 5-10% of vasovasostomies and up to 35% of vasoepididymostomies.
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Common procedures in infertility treatment such as semen analysis and intrauterine insemination (IUI) require collection of semen samples. These are most commonly obtained through masturbation, but an alternative to masturbation is use of a special collection condom to collect semen during sexual intercourse. Collection condoms are made from silicone or polyurethane, as latex is somewhat harmful to sperm. Some men prefer collection condoms to masturbation, and some religions prohibit masturbation entirely.
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Posted: 04/23/2004 procedures can be scheduled to take advantage of this time sequence,IVF.com ; Ovulation Induction. Retrieved Mars 7, 2010 such as intrauterine insemination or sexual intercourse. Also, patients that undergo IVF, in general, receive HCG to trigger the ovulation process, but have an oocyte retrieval performed at about 34 to 36 hours after injection by, a few hours before the eggs actually would be released from the ovary.
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Ava and Olivia are identical twins; Hazel, Riley, and Parker are fraternal triplets. Adam and Danielle had struggled with infertility, ultimately becoming pregnant both times by intrauterine insemination. During their first infertility journey, infertility was attributed to Adam's testosterone levels, sperm count, and sperm motility being low; and to Danielle's irregular ovulation. Adam was placed on Clomid, which helped his sperm counts, but his sperm motility remained low.
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Opie and her partner, painter Julie Burleigh,Lisa Boone (April 12, 2013), Garden is her canvas, flowers and edibles (and chickens) her paint Los Angeles Times. constructed working studios in the backyard of their home in South Central Los Angeles.Hilarie M. Sheets (January 27, 2013), Home Views, Bound by Ice or Leather The New York Times. In 2001, Opie gave birth to a boy named Oliver though intrauterine insemination.
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Artificial insemination (AI) is the deliberate introduction of sperm into a female's cervix or uterine cavity for the purpose of achieving a pregnancy through in vivo fertilization by means other than sexual intercourse. It is a fertility treatment for humans, and is common practice in animal breeding, including dairy cattle (see Frozen bovine semen) and pigs. Artificial insemination may employ assisted reproductive technology, sperm donation and animal husbandry techniques. Artificial insemination techniques available include intracervical insemination and intrauterine insemination.
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Approximate pregnancy rate as a function of total sperm count (may be twice as large as total motile sperm count). Values are for intrauterine insemination. (Old data, rates are likely higher today) The rate of successful pregnancy for artificial insemination are 10-15% per menstrual cycle using ICI,Utrecht CS News Subject: Infertility FAQ (part 4/4) and 15–20% per cycle for IUI. In IUI, about 60 to 70% have achieved pregnancy after 6 cycles.
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In 2004 the appellant and respondent began a same-sex relationship but at no point entered into a civil partnership. In 2008, following a course of intrauterine insemination the respondent gave birth to a baby girl (known throughout the case as 'B'). The respondent undertook most of the care for B but the appellant effectively acted as a co-parent to the child and helped to share the responsibilities. In 2011 the relationship broke down acrimoniously and the appellant left the family home.
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Sperm may be donated by the donor directly to the intended recipient woman or through a sperm bank or fertility clinic. Pregnancies are usually achieved by using donor sperm in assisted reproductive technology (ART) techniques which include artificial insemination (either by intracervical insemination (ICI) or intrauterine insemination (IUI) in a clinic, or intravaginal insemination at home). Less commonly, donor sperm may be used in in vitro fertilization (IVF). The primary recipients of donor sperm are single women, lesbian couples, and heterosexual couples suffering from male infertility.
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Approximate pregnancy rate varies with amount of sperm used in an artificial insemination cycle. Values are for intrauterine insemination, with sperm number in total sperm count, which may be approximately twice the total motile sperm count. Sperm count, or sperm concentration to avoid confusion with total sperm count, measures the concentration of sperm in a man's ejaculate, distinguished from total sperm count, which is the sperm count multiplied with volume. Over 15 million sperm per milliliter is considered normal, according to the WHO in 2010.
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Sperm banks and clinics usually 'wash' the sperm sample to extract sperm from the rest of the material in the semen. A cryoprotectant semen extender is added if the sperm is to be placed in frozen storage. One sample can produce 1–20 vials or straws, depending on the quantity of the ejaculate and whether the sample is 'washed' or 'unwashed'. 'Unwashed' samples are used for intracervical insemination (ICI) treatments, and 'washed' samples are used in intrauterine insemination (IUI) and for in- vitro fertilization (IVF) procedures.
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Albeit intrauterine insemination (IUI) might circumvent ASA present in the cervical mucus, in a study comprising 119 IUI, no live pregnancy was reported, suggesting involvement of other mechanisms of ASA. Since ASA are usually bound to sperm surface antigens with high affinity, ordinary wash-up used before ICSI is not effective. Thus, some authors recommend treatment of sperm with chymotrypsin/galactose to cleave ASA molecules. However, this method has not been adopted by clinicians as some concerns exist regarding a possible negative impact of this digestive enznyme on sperm surface receptors involved in fertilization.
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With a straw or a vial volume of 0.5 milliliter, the general guideline is that, for intracervical insemination (ICI), straws or vials making a total of 20 million motile spermatozoa in total is recommended. This is equal to 8 straws or vials 0.5 ml with MOT5, or 2 straws or vials of MOT20. For intrauterine insemination (IUI), 1–2 MOT5 straws or vials is regarded sufficient. In WHO terms, it is thus recommended to use approximately 20 million grade a+b sperm in ICI, and 2 million grade a+b in IUI.
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The reproductive tract (or genital tract) is the lumen that starts as a single pathway through the vagina, splitting up into two lumens in the uterus, both of which continue through the Fallopian tubes, and ending at the distal ostia that open into the abdominal cavity. In the absence of fertilization, the ovum will eventually traverse the entire reproductive tract from the fallopian tube until exiting the vagina through menstruation. The reproductive tract can be used for various transluminal procedures such as fertiloscopy, intrauterine insemination, and transluminal sterilization.
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How long the man has abstained prior to providing a semen sample correlates with the results of semen analysis and also with success rates in assisted reproductive technology (ART). Both a too short period of time since last ejaculation and a too long one reduce semen quality. A period of time of less than one day reduces sperm count by at least 20%. Longer periods of abstinence correlate with poorer results – one study found that couples where the man had abstained for more than 10 days before an intrauterine insemination (IUI) had only a 3% pregnancy rate.
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Donor sperm is prepared for use in artificial insemination in intrauterine insemination (IUI) or intra-cervical insemination (ICI). Less commonly, donor sperm is prepared for use in other assisted reproductive techniques such as IVF and intracytoplasmic sperm injection (ICSI). Donor sperm may also be used in surrogacy arrangements either by artificially inseminating the surrogate (known as traditional surrogacy) or by implanting in a surrogate embryos which have been created by using donor sperm together with eggs from a donor or from the 'commissioning female' (known as gestational surrogacy). Spare embryos from this process may be donated to other women or surrogates.
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Also, compared with samples obtained from masturbation, semen samples from collection condoms have higher total sperm counts, sperm motility, and percentage of sperm with normal morphology. For this reason, they are believed to give more accurate results when used for semen analysis, and to improve the chances of pregnancy when used in procedures such as intracervical or intrauterine insemination. Adherents of religions that prohibit contraception, such as Catholicism, may use collection condoms with holes pricked in them. For fertility treatments, a collection condom may be used to collect semen during sexual intercourse where the semen is provided by the woman's partner.
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Artificial insemination Artificial insemination is the introduction of sperm into the reproductive tract of a female by means other than sexual intercourse for the purpose of impregnating or fertilizing the female. In humans, artificial insemination may be used when a woman or her normal sex partner cannot, for any of a number of reasons, conceive by natural means. A number of artificial insemination strategies are available, including intracervical insemination (ICI) and intrauterine insemination (IUI). Compared with natural insemination, artificial insemination may be more invasive, and may require professional assistance and medical expertise, which will have a higher cost.
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With no hyperstimulation drugs, the treatment cycle relies on the spontaneous development of one follicle only and therefore the aspiration of only one egg from the follicle (it is possible however that the cycle can have more than one egg or no eggs). GnRH antagonists may still be given for ovulation suppression. In addition the patient will need to take hCG (as with other less invasive treatments such as ovulation monitoring and intrauterine insemination) to time egg collection as well as progesterone pessaries to supplement the body’s progesterone levels. Progesterone aids implantation and supports pregnancy in its early stages.
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Because assisted reproductive technologies, or ARTs, such as in vitro fertilization (IVF) or intrauterine insemination (IUI) require the induction of sperm cell capacitation outside of normal biological parameters, numerous methods have been developed to induce this process in mammalian sperm cells. Sperm cells are harvested through ejaculation or harvested from the caudal epididymis and allowed to liquefy at room temperature. Capacitation can then be induced by adding media designed to mimic the electrolytic composition of the fallopian tubes, where fertilization occurs. These media vary between species, but are saline-based and contain energy substrates such as lactate, pyruvate, and possibly glucose.
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Percoll was previously used in assisted reproductive technology (ART) to select sperm from semen by density gradient centrifugation, for use in techniques such as in vitro fertilization or intrauterine insemination. However, in 1996, Pharmacia sent out a letter to laboratories stating that Percoll should be used for research purposes only, not clinical. Pharmacia had not marketed it as a sperm preparation product; it had been repackaged and sold as such by third-party manufacturers. The FDA Warning Letter was due to concerns that PVP might cause damage to sperm (an unknown issue), and also that some batches of Percoll contained high levels of endotoxin (a known issue).
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Final maturation induction and release, such as by human chorionic gonadotropin (HCG or hCG) or recombinant luteinizing hormone (rLH), results in a predictable time of ovulation, with the interval from drug administration to ovulation depending on the type of drug. This avails for sexual intercourse or intrauterine insemination (IUI) to conviently be scheduled at ovulation, the most likely time to achieve pregnancy.IVF.com > Ovulation Induction Retrieved on Mars 7, 2010 As evidenced by clomifene-induced cycles, however, triggering oocyte release has been shown to decrease pregnancy chances compared to frequent monitoring with LH surge tests. Therefore, in such cases, triggering oocyte release is best reserved for women who require IUI and in whom LH monitoring proves difficult or unreliable.
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The sperm is stored in small vials or straws holding between 0.4 and 1.0 ml of sperm and cryogenically preserved in liquid nitrogen tanks. It has been proposed that there should be an upper limit on how long frozen sperm can be stored; however, a baby has been conceived in the United Kingdom using sperm frozen for 21 years and andrology experts believe sperm can be frozen indefinitely. The UK government places an upper limit for storage of 55 years. Before freezing, sperm may be prepared (washed or left unwashed) so that it can be used for intracervical insemination (ICI), intrauterine insemination (IUI) or for in-vitro fertilization (IVF) or assisted reproduction technologies (ART).
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Women with HIV have been shown to have decreased fertility which can affect available reproductive options. In cases where the woman is HIV negative and the man is HIV positive, the primary assisted reproductive method used to prevent HIV transmission is sperm washing followed by intrauterine insemination (IUI) or in vitro fertilization (IVF). Preferably this is done after the man has achieved an undetectable plasma viral load. In the past there have been cases of HIV transmission to an HIV-negative partner through processed artificial insemination, but a large modern series in which followed 741 couples where the man had a stable viral load and semen samples were tested for HIV-1, there were no cases of HIV transmission.
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Potential methods in unexplained infertility include oral ovarian stimulation agents (such as clomifene citrate, anastrozole or letrozole) as well as intrauterine insemination (IUI), intracervical insemination (ICI) and in vitro fertilization (IVF). In women who have not had previous treatment, ovarian stimulation combined with IUI achieves approximately the same live birth rate as IVF. On the other hand, in women who have had previous unsuccessful treatment, IVF achieves a live birth rate approximately 2–3 times greater than ovarian stimulation combined with IUI. IUI and ICI has higher pregnancy rates when combined with ovarian stimulation in couples with unexplained infertility, for IUI being 13% unstimulated and 15% stimulated, and for ICI being 8% unstimulated and 15% stimulated.
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Induction of final maturation also initiates the mechanisms that eventually result in ovulation, and thereby makes the oocytes destined to undergo ovulation unless artificial oocyte retrieval is performed first. Therefore, induction of final maturation is also called triggering oocyte release from the ovary, and the administration of pharmaceutical drugs to induce final maturation is colloquially called giving a "trigger shot", even if the plan is to perform artificial oocyte retrieval before ovulation.About.com Administration of a drug to trigger oocyte release without oocyte retrieval results in a predictable time of ovulation, with the interval from drug administration to ovulation depending on the type of drug. This avails for sexual intercourse or intrauterine insemination (IUI) to conveniently be scheduled at ovulation, the most likely time to achieve pregnancy.IVF.
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