68 Sentences With "intermediated" | Random Sentence Generator

In the case of Alexa and Siri, our content gets intermediated.

But the company ultimately sells third-party physical goods intermediated by human choices.

This work tour was built around the changing and dis-intermediated economy, a subject he talks about frequently.

"The lawsuit shows that pharmacy benefits managers are now also at risk of being dis-intermediated," he wrote.

We invested in SmartCommerce, led by CEO Jennifer Silverberg, which helps brands increase sales despite an increasingly dis-intermediated shopping experience.

"We have made it clear we are not prepared to be intermediated," said one of the bankers involved in the meeting.

Nonetheless, it is still not a properly intermediated market with multiple banks given lead manager roles on deals, especially for financials and sukuk offerings.

If Judge Leon believes HBO Now customers are intermediated by a distributor like Apple, then he should believe the exact same thing about Netflix.

"Opposing arguments are self-serving statements from those who profit by the way that trades are intermediated today," said IEX president and co-founder Ronan Ryan.

Cross-border bank lending booked in Hong Kong has roughly doubled in the past decade, much of it Chinese companies borrowing dollars intermediated through the territory.

That's all pretty wonky, but you can intuitively feel this problem throughout the digital economy, which is increasingly intermediated by a small handful of platforms and companies.

That said, "most sellers can expect their costs of payments processing to be reduced after they transition to eBay's intermediated payments model," eBay said in its announcement.

And German insurers' collective negotiations are "quite different from the US, where drug price negotiations with manufacturers are fragmented, and often intermediated by pharmacy benefit managers," she added.

The Bank of Korea said in a statement that it would improve credit policies of the Bank Intermediated Lending Support Facility, the bank's main tool to provide cheap loans to small businesses.

The beauty is that you don't need to be intermediated by so many layers as the amount of tech and money and everything needed for you to reach an audience of millions gets lower every year.

"Venezuelan bond investors range from taxi drivers to large companies, and everything in the middle," said Victor Silva of local brokerage Kapital, which has intermediated the sale of paper issued by Venezuela and state oil company PDVSA.

"This rising real economy leverage in itself creates macroeconomic risks, but also makes it more important to identify whether the particular form of debt or the particular ways in which credit flows are intermediated or managed are contributing further to the inherent risks," it said.

In a world that is seeing customers abandon part or all of their in-store and brick 'n' mortar shop in favour of online outlets like Amazon, brands such as Unilever are exploring new ways of having a more direct relationship with those same customers in a bid to not become intermediated.

In July 2020, the Romanian businessman Radu Budeanu admitted having intermediated a bribe from another businessman (whose identity remains unknown) to Udrea. The bribe was meant to make Udrea help the businessman renew long-term contracts between his commercial energy companies and the state-owned company Hidroelectrica. Although he initially promised Udrea US$5 million, Budeanu claimed to have intermediated several payments summing up to $3.8 million between November 2011 and February 2012.

The number of recoveries rises to 958, 7 patients are in ICU and no patients are on intermediated care. 2,363 analyses were made on the day. 29 July 2020: 19 new cases are confirmed, 5 of them due to an outbreak in the city of Bella Unión. The number of infected people rises to 1,237. The number of recoveries rises to 967, 6 patients are in ICU and no patients are on intermediated care.

Facets is a software program for Rasch analysis of rater- or judge-intermediated data, such as essay grades, diving competitions, satisfaction surveys and quality-of-life data. Other applications include rank-order data, binomial trials and Poisson counts.

2,100 analyses were made on the day. 25 July 2020: 9 new cases are confirmed. The number of infected people rises to 1,174. The number of recoveries rises to 947, 3 patients are in ICU and no patients are on intermediated care.

1,488 analyses were made on the day. 26 July 2020: 18 new cases are confirmed. The number of infected people rises to 1,192. The number of recoveries rises to 948, 5 patients are in ICU and no patients are on intermediated care.

"Summary of responses received in respect of the EU consultation on legal certainty of securities holding and transactions", European Commission However, the phenomena of dematerialization of securities issued by large firms is mostly undertaken via Central Securities Depository, a national or regional institution holding the notary function, such as the Depository Trust Company (DTC) in the United States or Euroclear Group in part of the EU, which itself entrusts banks and investment firms to act as intermediaries between issuers and investors for the custody of these securities. Therefore, dematerialized securities are often referred as intermediated securities, in particular by the Unidroit convention on substantive rules for intermediated securities.

In January 2003 IAG, Insurance Australia Group, purchased NZI when acquiring Aviva's general insurance business, and NZI is now a subsidiary of IAG New Zealand Ltd. Aviva predecessor General Accident bought NZI in 1989. NZI focuses on providing products to the intermediated market; i.e. brokers and banks.

Meanwhile, Prague German intermediated between Upper German and East Central German, influencing the foundations of modern standard German. At the same time and place, the teachings of Jan Hus, the rector of Charles University and a prominent reformer and religious thinker, influenced the rise of modern Czech.

1,943 analyses were made on the day. 27 July 2020: 13 new cases are confirmed. The number of infected people rises to 1,202. The number of recoveries rises to 951, 5 patients are in ICU and no patients are on intermediated care. 1,955 analyses were made on the day.

K Desktop Environment 2 introduced significant technological improvements compared to its predecessor. DCOP (Desktop COmmunication Protocol), a client- to-client communications protocol intermediated by a server over the standard X11 ICE library. KIO, an application I/O library. It is network transparent and can access HTTP, FTP, PoP, IMAP, NFS, SMB, LDAP and local files.

Several years later, in Alice v. CLS Bank, the Supreme Court readdressed the patent eligibility of a business method. It held patent ineligible a method of securing intermediated settlement—a form of electronic escrow. In invalidating Alice's patent, the Court announced a two- step test based on the Court's earlier decisions in Mayo v.

Transaction Banking (TB) can be defined as the set of instruments and services that a bank offers to trading partners to financially support their reciprocal exchanges of goods (e.g.trade), monetary flows (e.g., cash), or commercial papers (e.g., exchanges). TB allows banks to maintain close relationship with their corporate clients so banks don’t want to be dis-intermediated by other players.

McKnight, D., H., Chervany, N. L. (2001) "Conceptualizing Trust: A Typology and E-Commerce Customer Relationships Model". Proc. of the 34th Hawaii Int. Conf. on System Sciences. For example, inter-personal relationship between the buyer and the seller has been dis- intermediated by the technology,Giddens, A. (1991) Modernity and Self- identity: Self and Society in the Late Modern Age.

Temuco Formation a sedimentary formation near the city of Temuco in southern Chile. The formation crops out in the western part of Labranza Basin at the footfills of the Chilean Coast Range. It overlies the Bahía Mansa Metamorphic Complex and underlies sediments of Holocene age. The formation is thought to represent ancient river systems of low and intermediated energy near an area of volcanism around cerro Ñielol.

In 2003, Unidroit started a negotiation process with a view to harmonise the material aspects of intermediated securities. The purpose is to achieve a further step towards legal integration of securities markets, that consist not only in identifying the applicable law, but also in harmonising some parts of the legislation of the signatory States. These negotiations eventually reached the adoption, in October 2009, of the Geneva Securities Convention.

The bank lending channel theorizes that changes in monetary policy will shift the supply of intermediated credit, especially credit extended through commercial banks. The bank lending channel is essentially the balance sheet channel as applied to the operations of lending institutions. Monetary policy actions may affect the supply of loanable funds available to banks (i.e. a bank's liabilities), and consequently the total amount of loans they can make (i.e.

CBOE offers binary options on the S&P; 500 (SPX) and the CBOE Volatility Index (VIX). The tickers for these are BSZ and BVZ, respectively. NADEX, a U.S.-based Commodity Futures Trading Commission (CFTC) regulated exchange, launched binary options for a range of Forex, commodities, and stock indices' markets in June 2009,. On March 30, 2010 the CFTC issued an amended Order of Designation to allow trades on NADEX to be intermediated.

In E. coli, MviN is an essential protein which when defective results in the accumulation of polyprenyl diphosphate-N-acetylmuramic acid-(pentapeptide)-N-acetyl-glucosamine, thought to be the peptidoglycan intermediated exported via MviN. In Mycobacterium tuberculosis, MviN is thought to play an essential role in peptidoglycan biosynthesis. Another MVF protein, MurJ, functions as a peptidoglycan biosynthesis protein. A 3-d structureal model shows that MurJ contains a solvent-exposed cavity within the plane of the membrane.

MALS-39 provides all the aviation supply and intermediated level of aircraft maintenance, avionics, and ordnance support for nine flying squadrons. Additionally, whenever the flying squadrons deploy, whether in the United States or overseas, MALS-39 augments these squadrons with its Marines to ensure optimum aviation logistics support in every clime and place. During the last ten years, Marines from MALS-39 have seen action throughout the world. Elements of the squadron participated in Operation Desert Storm and in the liberation of Kuwait.

Born in Białystok, Piekarski moved to Brazil with fellow countryman Krzysztof Nowak in 1996 to play for Atlético Paranaense. After one year, he joined Flamengo where he stayed for five months, also playing for Mogi Mirim before returning to Europe. He retired in 2002 after an ankle injury sustained in a match for Anorthosis Famagusta, also suffering two cruciate ligaments injuries in his knees before. After retirement, he worked as an agent and intermediated the transfer of Roger Guerreiro and Edson to Poland.

The earliest known tianxia view of the world in Korean history is recorded in Goguryeo epigraphs dating to this period. Dongmyeong of Goguryeo was a god-king, the Son of Heaven, and his kingdom was the center of the world. As the descendants of the Son of Heaven, the kings of Goguryeo were the Scions of Heaven (), who had supreme authority and sacerdotally intermediated between Heaven and Earth. The Goguryeo concept of tianxia was significantly influenced by the original Chinese concept, but its foundation laid in Dongmyeong.

After the coup, Peidl became chair of the printer's trade union again. Representing the working class, he participated in the grand coalition talks intermediated by Allied representative George Clerk in early November. Peidl went into exile in Austria on 18 November 1919, after receiving an increasing number of death threats from far-right paramilitary groups. He resided in Vienna and Sankt Radegund bei Graz, where he worked as a proofreader, until his return to Hungary in November 1921, where he resumed his trade union activity.

On 5 February 2015, Federal Police launched the ninth phase of Car Wash, called "My Way". It has served 62 search and seizure warrants, temporary and preventive arrests and enforcement orders in four states of Brazil, to gather evidence about operators who intermediated the payment of bribes and kickbacks under Petrobras. Evidence was also collected regarding payments under BR Distribuidora, a subsidiary of Petrobras. During this phase forty-eight works of art were seized at 's house and taken to the Oscar Niemeyer Museum.

Auldbrass Partners seeks concentrated positions in excellent companies with strong sustainable growth and resilience that can be reasonably expected to achieve liquidity in 3-5 years. Auldbrass Partners has a company focused, data driven approach which targets gross returns of 2.0x MOIC and 20%+ IRRs. Through both direct GP and intermediated relationships built over decades of successful investing, Auldbrass Partners has established a network of 200 funds and 300 general partner/limited partner relationships from which it sources its deals.[3] Auldbrass Partners team members have completed over $5 billion (500 fund transactions) of transactions.

Collectively, these measures enhance the value of the report to investors and consequently, to the company itself. The intermediated research framework includes the further protections; ensuring that the independent research firms involved have no investment banking or brokerage operations in their business models; conduct no traditional company-paid research; deliver a standard template for analysis of every company so that all standard topics are covered; and avoiding ratings and target prices in the reports, since these can risk becoming a focus of pressure exerted on the research provider by the subject company.

The Unidroit convention on substantive rules for intermediated securities, also known as the Geneva Securities Convention, was adopted on 9 October 2009. It has been signed by only one of the 40 negotiating States (Bangladesh), but not entered into force. The official commentary is was published in 2012. This convention adopted under the aegis of the International Institute for the Unification of Private Law (Unidroit) complements the "Hague Securities Convention" adopted on 17 January 2002 by the Hague Conference on Private International Law, which entered into force in 2017.

While studying at Stanford, Scheinman was awarded a fellowship sponsored by George Devol, the inventor of the Unimate, the first industrial robot. Scheinman traveled with Devol and Joe Engelberger to Unimation and several of its customers, observing robot applications, including loading and unloading machines, handling material and early attempts to do spot welding. These early robots were hydraulic and programmed by teaching the robot a series of individual points that the robot would repeat each cycle. Some path control could be achieve by teach many intermediated points, but true path following was not possible.

An aryl aryl coupling thought to be catalyzed by a cytochrome P450 enzyme to form an aromatic ring system occurs. Staurosporine 2 This is followed by a nucleophilic attack between the indole nitrogens resulting in cyclization and then decarboxylation assisted by StaC exclusively forming staurosporine aglycone or K252c. Glucose is transformed to NTP-L-ristoamine by StaA/B/E/J/I/K which is then added on to the staurosporine aglycone at 1 indole N by StaG. The StaN enzyme reorients the sugar by attaching it to the 2nd indole nitrogen into an unfavored conformation to form intermediated O-demethyl-N-demethyl-staurosporine.

In 1919, he was sent by the government to preside over the Albanian delegation to the Paris Peace Conference. He intermediated through the Pope Benedict XV for opposing the Venizelos–Tittoni agreement for partitioning of Albania between Italy and Greece. He also participated in the Congress of Lushnje in January 1920 and, as a representative of the Catholic community, was elected to the four-member High Regency Council (). Together with Aqif Pasha Biçaku he took part in a coup d’état in December 1921 and was later relieved of his duties on the High Council by Ahmet Zogu.

Regarding nominees who are the registered owners of securities, the controlling legislation for the basic nominee relationship is Article 8: Investment Securities of the Uniform Commercial Code as amended, which was enacted by the State legislatures. Article 8 provides for a system of heavily-intermediated securities holding where transfers are by a series of book-entries and stock certificates are registered in the name of a designated nominee entity. This nominee must issue proxies to the beneficial owners of the stocks in order for these beneficial owners to have a right to vote in stockholders' meetings.

On 23 August 2017, the Federal Police launched a new phase named Court orders were carried out in the Federal District, and in the states of Bahia and São Paulo, totalizing four search and seizure warrants. The attorney Tiago Cedraz, son of the Federal Court of Accounts minister, Aroldo Cedraz, was one of the targets of the search warrants. According to the investigations, the lobbyist Jorge Luz, arrested in Curitiba, stated that Cedras intermediated talks betweens the north-American company Sargeant Marine and Petrobras, receiving 20 thousand dollars in bribes for the job in bank accounts kept in Switzerland, in the name of offshore companies.

Several scholars have recognised parallels between the philosophy of Pythagoras and Plato and that of the Upanishads, including their ideas on sources of knowledge, concept of justice and path to salvation, and Plato's allegory of the cave. Platonic psychology with its divisions of reason, spirit and appetite, also bears resemblance to the three gunas in the Indian philosophy of Samkhya. Various mechanisms for such a transmission of knowledge have been conjectured including Pythagoras traveling as far as India; Indian philosophers visiting Athens and meeting Socrates; Plato encountering the ideas when in exile in Syracuse; or, intermediated through Persia. However, other scholars, such as Arthur Berriedale Keith, J. Burnet and A. R. Wadia, believe that the two systems developed independently.

The conference was intermediated by the British emissaries with the idea of unifying the Albanian political spectrum against the Fascists, similar to AVNOJ in Yugoslavia. The agreement established a Committee of National Salvation which should take the lead over the Albanian resistance movement. The movement would take into consideration the Albanian national cause, making possible the creation of a Greater Albania, with the annexation of Albanian populated areas to a post-war Albanian state. On the part of the National Liberation Movement, the delegation was led by Ymer Dishnica, a member of the Politburo of the Central Committee of the Communist Party of Albania and Mustafa Gjinishi. Balli Kombëtar was represented by Skënder Muço, Hysni Lepenica, Mit’hat Frashëri, and Hasan Dosti (head of delegation) between others.

Unfortunately, with the subject company paying directly for these services, this form of research suffers from a real or perceived lack of objectivity, which reduces its value to investors and hence to the companies themselves. Intermediated research improves significantly upon the sponsored research model, by introducing important safeguards into the commercial and research process framework. The key structure is that the company has no choice in its allocation to a research provider; once matched with the research provider, the company is under a long term contract in order to minimize commercial pressure or influence; and the fees paid to the research provider are not sufficiently material for the company to be able to exert any influence over the content or conclusions of the research report.

Under a strict definition, where helicopter drops are simply transfers from the central bank to the private sector financed with base money a number of economists have argued that they are already occurring. In 2016, the European Central Bank (ECB) launched a TLTRO programme lending money to banks at negative interest rates, which amounts to a transfer to banks. Also, the use of differential interest rates on tiered reserves to support commercial banks' profitability in the face of negative interest rates, opens up another source of helicopter drop - albeit intermediated by banks. In the case of the Eurozone, the use of TLTROs is believed by some economists to provide a legal and administratively tractable means of introducing transfers to households.

The Menlo Report attempts to summarize a set of basic principles to guide the identification and resolution of ethical problems arising in research of or involving ICT. ICT is a general umbrella term that encompasses networks, hardware and software technologies that involve information communications pertaining to or impacting individuals and organizations. ICT has increasingly become integrated into our individual and collective daily lives, mediating our behaviors and communications and presenting new tensions that challenge the applications of these guiding principles. The challenges of ICTR risk assessment derive from three factors: the researcher-subject relationships, which tend to be disconnected, dispersed, and intermediated by technology; the proliferation of data sources and analytics, which can heighten risk incalculably; and the inherent overlap between research and operations.

He is the author of Security Interests in Personal Property (with Steven Harris, 6th ed. 2015). Mooney was awarded the Distinguished Service Award in 2002 by the American College of Commercial Finance Lawyers. He served as a United States Delegate at the Diplomatic Conference for the Cape Town Convention on International Interests in Mobile Equipment and the Aircraft Protocol, and at the Diplomatic Conference for the Unidroit (Geneva) Convention on Intermediated Securities. Mooney also served as a Co-Reporter for the Drafting Committee for the Revision of Uniform Commercial Code (UCC) Article 9 (Secured Transactions), as the American Bar Association (ABA) Liaison-Advisor to the Permanent Editorial Board for the UCC, and as a member of Council and Chair of the Committee on UCC of the ABA Business Law Section.

In finance, intermediated research is a type of fundamental analysis or investment analysis of a business to establish its value for investors that attempts to avoid commercial pressure or influence. Many banks and brokers provide research to the investment community, however this form of research suffers from a real or perceived lack of objectivity. For example, this research may be subject to influence from within a bank from, say, investment bankers keen to win company’s IPO mandate. An alternative form is known as independent research or alternative research, this is research that is not provided by a bank or broker. However, someone has to fund the costs of conducting the research, and when the funder is the company being researched, this form of independent research is termed “sponsored” or “company-paid” research.

Nutrient exchanges and communication between a mycorrhizal fungus and plants. Mycorrhizal networks (also known as common mycorrhizal networks or CMN) are underground hyphal networks created by mycorrhizal fungi that connect individual plants together and transfer water, carbon, nitrogen, and other nutrients and minerals. The formation of these networks is context dependent, and can be influenced by factors such as soil fertility, resource availability, host or myco-symbiont genotype, disturbance and seasonal variation (due to enrichment of nitrogen in soil affect michozial communities or effect of human activities of human affecting nitrogen cycle). By analogy to the many roles intermediated by the World Wide Web in human communities, the many roles that mycorrhizal networks appear to play in woodland have earned them a colloquial nickname: the Wood Wide Web..

The Stock Exchange at 10–12 Broad Street, 1882 The earliest recorded organization of securities trading in New York among brokers directly dealing with each other can be traced to the Buttonwood Agreement. Previously, securities exchange had been intermediated by the auctioneers, who also conducted more mundane auctions of commodities such as wheat and tobacco. OCRed document unreable On May 17, 1792, twenty four brokers signed the Buttonwood Agreement, which set a floor commission rate charged to clients and bound the signers to give preference to the other signers in securities sales. The earliest securities traded were mostly governmental securities such as War Bonds from the Revolutionary War and First Bank of the United States stock, although Bank of New York stock was a non-governmental security traded in the early days.

If the initial stress minus the sliding frictional stress (with respect to the initial crack) is low, and the specific fracture energy or the strength of the crustal material (relative to the amount of stress) is high then slow earthquakes will occur regularly. In other words, slow earthquakes are caused by a variety of stick-slip and creep processes intermediated between asperity-controlled brittle and ductile fracture. Asperities are tiny bumps and protrusions along the faces of fractures. They are best documented from intermediate crustal levels of certain subduction zones (especially those that dip shallowly — SW Japan, Cascadia, Chile), but appear to occur on other types of faults as well, notably strike-slip plate boundaries such as the San Andreas fault and "mega- landslide" normal faults on the flanks of volcanos.

The Airline Tariff Publishing Company (commonly known as ATPCO) is a privately held corporation that engages in the collection and distribution of fare and fare-related data for the airline and travel industry. ATPCO currently works with more than 427 airlines worldwide, and it supplies more than 99% of the industry’s intermediated fare data to all the major airfare pricing engines, storing over 211 million active fares in its database. The users of ATPCO’s data are Global Distribution Systems (GDS), such as Sabre, Amadeus, Travelport, and their associated travel agents; the Central Reservation Systems (CRS) of airlines; online travel agencies (OTA) such as Expedia, Orbitz, and Travelocity; and other service providers in the travel industry. In November 2016, ATPCO announced that Rolf Purzer will be the new President and CEO, effective February 1, 2017.

In the United States Brokerage account agreements under Article 8 of the Uniform Commercial Code create a legal relation known as "custodianship", which is distinguished from the traditional concept of a trust. For example, in the context of the Individual Retirement Account (IRA), a brokerage firm distinguishes its custodial account IRAs from trust IRAs when seeking IRS tax approval for an IRA plan which is part of a brokerage account agreement. The treatment of a brokerage account based IRA as a trust for tax purposes is largely a legal fiction. If Article 8 is set aside and the brokerage account is considered purely under principles of common law, there is a possibility of construing the collection of brokerage accounts in the intermediated custodial holding chain as a collection of directed agency nominee trusts.

Mediation is perhaps the key theoretical idea behind activity: we don't just use tools and symbol systems; instead, our everyday lived experience is significantly mediated and intermediated by our use of tools and symbols systems. Activity theory helps frame, therefore, our understanding of such mediation. Besides a strong focus on material and symbolic mediation, internalizationIn Vygotskyan psychology internalization is a theoretical concept that explains how individuals process what they learned through mediated action in the development of individual consciousness. of external (social, societal, and cultural) forms of mediation, another important, aspect of first generation CHAT is the concept of the zone of proximal development (ZPD), meaning, as advanced in Mind in Society (1978), "the distance between the actual developmental level as determined by independent problem solving and the level of potential development as determined through problem solving under adult guidance or in collaboration with more capable peers".

In countries where the first interpretation prevails, the investor shall dispose of a right to "rivindicate" (claim as one's own) which will allow him a speedy recover of the securities. In countries where the second interpretation prevails (the US and, to a certain extent the recourse to trust deposits in common law countries), the investor would only dispose of a right of claim, that will oblige him, except when the contrary is specified, to share with other creditors of the insolvent intermediary the product of the winding up of the intermediary in prorate of the value of the security.France Drummond: " Intermediated securities: reflections on a new concept in French financial markets law ", Law and Financial Markets Review, September 2007, p. 435. This second interpretation does not comfort the investor, even when it is backed by experienced lawyers (see case of Banco Santander's securities deposited with Lehman Brothers).

In the business, management, economic and political-science literatures, nonmarket is typically associated with government, compared to other non-economic institutions, as in economist Baron’s (1995: 47) often quoted definition in the strategic-management field: > The nonmarket environment includes the social, political, and legal > arrangements that structure interactions outside of, but in conjunction > with, markets and private agreements. The nonmarket environment encompasses > those interactions between the firm and individuals, interest groups, > government entities, and the public that are intermediated not by markets > but by public and private institutions. Public institutions differ from > markets because of characteristics such as majority rule, due process, broad > enfranchisement, collective action, and publicness. Activities in the > nonmarket environment may be voluntary, as when the firm cooperates with > government officials, or involuntary, such as when government regulates an > activity or an activist group organizes a boycott of a firm’s product.

He backed the efforts by Grand Master Hermann von Salza to reach a reconciliation between Emperor Frederick II and Pope Gregory IX and sealed a 1230 peace agreement in the church of San Germano. He later also intermediated in the conflict between the emperor and his rebellious son King Henry VII; in 1237, he supported the election of Henry's younger brother King Conrad IV. However, in his later years, having established marital relationships with the Bohemian Přemyslid dynasty and the Counts of Andechs, he turned away from straitened Frederick II towards the ultramontane party. In 1247 he achieved the election of his younger son Philip as Archbishop of Salzburg. Bernhard von Spanheim fountain, Klagenfurt A territorial prince (princeps terre) at his own judgement, Bernhard concentrated on regional politics and aimed at extending his estates against rivalling territorial princes like Patriarch Berthold of Aquileia or the Bishops of Bamberg controlling the city of Villach and important trade routes to Italy, albeit without much success.

The underlying idea is that, while "intrinsic law" is intangible, since it is tributary to the legislation under which the issuer is incorporated, "substantive law" is, on the contrary, quite volatile, since it is subject to the place where the security is localised and/or traded. This distinction is ancient and draws back to the time where foreign investors used to repatriate paper securities subscribed with issuers incorporated under a different constituency. The title transfer of these securities (whether as a final transfer, or as a collateral) outside their constituency of origin could therefore be submitted to a law different from the law of the issuer: either the law convened by the parties (lex contractus), or, more often, the law of the place where the securities where located at the time of the transfer (lex rei sitae).John J.A. Burke, Anatoly Ostrovskiy: "The intermediated securities system / Brussels I breakdown" / In: The European legal forum: Forum iuris communis Europae 2007, v.

Both compounds are members of the specialized proresolving mediators class of PUFA metabolites in that they possess potent anti-inflammatory activity; however, only PDX inhibited human platelet aggregation responses. Subsequent studies found that various other dihydroxy-E,Z,E-double bound-configured PUFA but not those with E,E,E or E,E,Z double bond configurations share with PDX anti-platelet activity. Cells make PDX by metabolizing DHA by double oxygenation a 15-lipoxygenase to form the 10R,17S-hydroxperoxy intermediated which is reduced its 10R,17S-hydroxyl product, PDX, probably by cytosolic GPX1 (i.e. glutathione peroxidase 1). Serial metabolism two different lipoxygenases or a lipoxygenase and a cytochrome P45) on PUFA possessing three double bonds in a 1Z,4Z,7Z configuration may also make a 1,7-dihydroxy 2E,4Z,6E product. Other platelet- inhibiting dihydroxy-E,Z,E-PUFA are: 10R,17S-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid (10R,17S-diHDHA); 8S,15S-dihydroxy-5Z,9E,11Z,13E-eicosatetraenoic acid (8S,15S-diHETE); 9S,16S-10E,12Z,14E-octadecatrienoic acid (linotrin-1); and 9R,16S-10E,12Z,14E-octadecatrienoic acid (linotrin-2).