140 Sentences With "having a role in" | Random Sentence Generator

Pakistan has vehemently denied having a role in the attacks.

Pakistan has vehemently denied having a role in the incident.

WikiLeaks publisher Julian Assange denied having a role in the email.

Fujimori is accused having a role in the authorizing the killings.

New Delhi blamed Islamabad, which denies having a role in the attack.

Excited by the prospect of having a role in the awards ceremony?

What is it like having a role in a women-led film?

Obama possibly having a role in the Clinton administration—if Clinton wins. Mrs.

Police said both men had confessed to having a role in the Aug.

Mr. Najib has denied meeting Ms. Altantuya or having a role in her death.

"We're an American company," he said, when asked about CFIUS having a role in the deal.

But despite this relationship, no one has previously accused Kushner of having a role in the incident.

Mullah Saadyar has also been accused of having a role in the stoning of a local woman, Rukhshana.

Actress Felicity Huffman is set to plead guilty Monday to having a role in a widespread college admissions bribery scandal.

Last month, prosecutors dropped all remaining charges against the police officers accused of having a role in Mr. Gray's death.

When reached by BuzzFeed News, Navarra neither confirmed nor denied having a role in the egg and declined to comment further.

The Dalits, often translated as the oppressed, are communities that have been excluded from having a role in India's caste system.

As evidenced by Zuck's answers, he was more open to the idea of Facebook having a role in the fake news fiasco.

Kraninger has denied having a role in setting or developing the immigration policy but said that she attended meetings relating to its implementation.

She did not mention having a role in any decision on whether to return those found to have been stolen by the Nazis.

Iran has also accused the U.S. of having a role in a deadly attack earlier this month on a military parade in Ahvaz, Iran.

The Turkish government blames Gülen and his followers for having a role in the failed 2016 coup, and also declared his movement a terrorist organization.

Pakistan has vehemently denied having a role in the incident, which New Delhi says was carried out by Pakistan-based terrorist group Jaish-e-Mohammed.

She also suggested she'll be an ally for pharmacy benefit managers, the middlemen who are increasingly getting blamed for having a role in rising drug prices.

The irony of an old-school warrior having a role in revolutionizing the game — or ruining it, depending on your viewpoint — is not lost on Backman.

The crown prince has denied having a role in the killing, and Riyadh has reportedly put 11 people on trial for the crime in nonpublic proceedings.

The importance of tech is magnified in these kinds of incidents, but it's probably an extension of how tech is increasingly having a role in every story.

Bannon spent seven years in the Navy as a surface warfare officer after college and is reportedly interested in having a role in shaping military and foreign policy.

"I am talking to colleagues about how we can look at parliament having a role in going into that and, if you like, coming out of that," she said.

The Federal Aviation Administration said on Monday that Boeing needed more time to finish changes in a flight-control system suspected of having a role in two deadly crashes.

Judiciary spokesman Gholamhossein Esmaili said some of those accused of having a role in the plane disaster had been arrested, although he did not say how many or identify them.

An amendment to a bill on US countermeasures said that "commanders" and "authorities having a role in" the killing of Qassem Soleimani in a drone strike on Friday were also terrorists.

During this past season, Beltran told Cashman that he would be retiring at the end of the season and that he would be interested in having a role in the Yankees organization.

We have written so much about Russia, we've written about the different aspects of what's been called the "collusion case," we've written about Middle Eastern countries having a role in this investigation.

Kraninger, who works closely with Mulvaney at the Office of Management and Budget, has denied having a role in setting or developing that policy but said she attended meetings relating to its implementation.

In a backward way, Weiner wound up having a role in one of the first big progressive electoral victories of the decade (your mileage may vary on what has happened under de Blasio since).

These firms, from Facebook to Twitter, have now very publicly admitted to having a role in facilitating the spread of foreign influence during elections and, more generally, of circulating massive amounts of disinformation the world over.

When confronted about his role in helping form Trump's "zero tolerance" immigration policy in June, Wolf denied having a role in its development, saying the direction was given through an executive order and the attorney general's policy.

"The prospect of direct rule in Northern Ireland and the Irish government's insistence on having a role in that — an appropriate role consistent with the Good Friday Agreement — is not where we want to be," he said.

It wasn't long after he was announced as having a role in the next Game of Thrones season that he casually dropped a massive spoiler about his role — and it doesn't sound as though he has any remorse.

But we do have an interest in freedom of navigation in the rule of international law, in the peaceful resolution of dispute, and in ASEAN having a role in an issue which is this important in our neighborhood.

Asked this week about the United States's view on the Syrian government having a role in Raqqa, State Department spokeswoman Heather Nauert called that a "hypothetical," and said the focus now is on providing locals with basic human needs.

He also complained that the United States had convicted Mehmet Hakan Atilla, the deputy director of the state-owned Halkbank, for having a role in conspiring to violate American sanctions against Iran, and was pursuing further cases against the bank.

But she faced opposition after admitting she did not disclose that her brother held a senior position at Barclays during her time at the central bank, despite her having a role in drafting a code of conduct policy that required a disclosure of such conflicts.

While one doesn't normally think of the U.S. Environmental Protection Agency as having a role in national security, ensuring the Tidewater region can support military installations and thousands of personnel ready to deploy at a moment's notice requires clean water supplies, reliable training ground, energy innovation and safe communities.

Chinese officials have accused the US and other foreign governments of having a role in backing the pro-democracy protests that have roiled Hong Kong in recent weeks, protests that were launched in response to a bill that would have allowed Hong Kong to extradite individuals to mainland China.

Until then, he remains in the high-security wing of Manhattan's federal jail, though his case has not gone quiet — just last week, The Times explored some of the crimes he is accused of having a role in, including murders, torture, kidnappings and an attempt to smuggle seven tons of cocaine in cans of jalapeños.

As unpalatable as Syrian dictator Bashar al-Assad having a role in the country's future governance might be for some Western countries, when the US and Russia are in open dispute over Syria, the prospects for reaching a lasting political settlement become bleaker, and the regime may even feel emboldened to commit further atrocities.

Mike PenceMichael (Mike) Richard PenceFEC chair calls on Trump to provide evidence of NH voter fraud Five years after Yazidi genocide, US warns ISIS is rebounding Log Cabin Republicans endorse Trump MORE (R- Ind) was chosen instead, but Fox decided to sever the ties regardless, due to the potential of Gingrich having a role in a Trump administration if the Republican wins in November.

NCAM has been implicated as having a role in cell–cell adhesion,Pathology Outlines neurite outgrowth, synaptic plasticity, and learning and memory.

Nineteen members of the so-called Islamic Revolutionary Council of Iran in 1979 were also prosecuted for having a role in the popular riot of Gowharshad Mosque.

Disturbed and altered sleep has also been suggested as having a role in dissociative disorders in general and specifically in DID, alterations in environments also largely affecting the DID patient.

PNMA1, 2 and 3 were found in the serum of patients with paraneoplastic neurological disorders. The family also includes modulator of apoptosis 1, having a role in death receptor-dependent apoptosis.

OPG has been identified as having a role in tumour growth and metastasis, heart disease, immune system development and signalling, mental health, diabetes, and the prevention of pre-eclampsia and osteoporosis during pregnancy.

A grand jury indicted some white miners for having a role in the massacre; none was convicted. Henry Stevens, as leader of the AAMA, was indicted on three counts of intent to kill.

Interferon-γ has been shown to be a crucial player in the immune response against some intracellular pathogens, including that of Chagas disease. It has also been identified as having a role in seborrheic dermatitis.

American Mathematical Society, Providence, RI, 2004. xii+325 pp. In addition to their role in geometry, nilmanifolds are increasingly being seen as having a role in arithmetic combinatorics (see Green–Tao ) and ergodic theory (see, e.g., Host–Kra).

He has accused the Kenyan government of former President Daniel arap Moi of trying to cover up Miss Ward's murder to prevent damage to the tourist industry. A former MI6 agent has admitted having a role in the case.

Clinton Pardons McColl denied having a role in the bank foundation's contribution to the Clinton library, saying the foundation had also donated $500,000 to the presidential library of George H.W. Bush and $225,000 to the library of Ronald Reagan.

Again, the robe was an important symbol in this transmission. Apart from having a role in texts and lineage, Mahākāśyapa has often been depicted in Buddhist art as a symbol of reassurance and hope for the future of Buddhism.

The differences in the niche of certain species may play a role in their behaviours. Lepidophagous behaviours only exist in some species. Adaptive radiation has been mentioned in many articles as having a role in the evolution of lepidophagy. There is some evidence to support this but much is also unclear.

On 12 February 2008, Borodoloi was remanded in Chandmari Police Custody for 5 days and charged under the Unlawful Activities (Prevention) Act with "having a role in fund collecting for the United Liberation Front of Assam (ULFA)" and under sections 120B and 121 of the Indian Penal Code for "waging a war against the State".

A SUMOplot Analysis conducted of Homo sapiens CXorf66 protein, discovered a high probability of a sumolyation motif at position K241, alongside low probability motifs at K316 and K186. With sumoylation having a role in various cellular processes like nuclear-cytosolic transport and transcriptional regulation, it is expected CXorf66 is modified by a SUMO protein post-translation.

Sam and Luna are taken to a hospital while Emma runs off to her grandmother's for safety. Sam tells Luna about Emma and swears to kill the shifter-murderers. Luna decides to let Marcus' mother into having a role in Emma's life until they find the killer. Sam wants to help Andy with the case regarding the shifter murders.

Kruppel-like factor 13, also known as KLF13, is a protein that in humans is encoded by the KLF13 gene. There is some evidence for KLF13 having a role in obesity. A methylation site, cg07814318, within the first intron of KLF13 has been associated with obesity and orexigenic processes. Ghrelin levels also positively correlated with methylation levels of cg07814318.

Tyrosinase is required for melanocytes to produce melanin from the amino acid tyrosine. Albinism may be caused by a number of other genes as well, like OCA2, SLC45A2, TYRP1, and HPS1 to name some. In all, already 17 types of oculocutaneous albinism have been recognized. Each gene is related to different protein having a role in pigment production.

Z from chromatin. In brain tissue, ANP32E together with Cpd1 regulate protein phosphatase 2A activity at synapses during synaptogenesis and has been observed to form a complex with ANP32A and SET that stabilizes short-lived mRNAs containing AU-rich elements, as well as having acetyltransferase inhibitory activity (in a complex with SET) and having a role in chromatin remodeling and transcriptional regulation.

Patti was ultimately convicted on April 14, 2010, for murder and sentenced to life imprisonment to be served in a regular prison facility; he admitted having a role in torture, albeit justifying his acts. Legislators from ARI, with government support, attempted to change Argentine law to prevent those accused of involvement from torture from taking public positions, a move which is highly accepted.

The speech was criticized by a reporter from The Wall Street Journal, who found the speech largely absent of emotion, while a National Review columnist criticized Obama for refusing to acknowledge Islamic terrorism as having a role in the shooting. On December 6, 2015, in his speech addressing terrorism, Obama included the Fort Hood shooting among Islamic inspired terrorist incidents.

Transmembrane protein 131 (TMEM131) is a protein that is encoded by the TMEM131 gene in humans. The TMEM131 protein contains three domains of unknown function 3651 (DUF3651) and two transmembrane domains. This protein has been implicated as having a role in T cell function and development. TMEM131 also resides in a locus (2q11.1) that is associated with Nievergelt's Syndrome when deleted.

First elected Governor in 1683, Treat was supplanted by Sir Edmund Andros in 1687, making Connecticut part of the Dominion of New England. Treat is credited with having a role in concealing the state's charter in the Charter Oak, and resumed his job as governor when the dominion scheme fell apart in 1689. He was re-elected annually until being defeated by Fitz-John Winthrop in 1698.

In addition, inhibition of DLK or JNK delays radial migration and disrupts the formation of the neocortex in mice. Another important function of the developing mammalian nervous system is neuronal apoptosis. The absence of DLK also protects cultured mice sensory neurons from apoptosis that would normally be triggered by a lack of NGF. This, among other experiments, heavily implicates it as having a role in neuronal apoptosis.

Stephen L. Ondra is the founder and Chief Executive Officer of North Star Health Care Consulting. A neurosurgeon and neuroscientist, Ondra has also served in senior positions in the Federal government, having a role in health reform efforts and the implementation of the Affordable Care Act. He advises corporations, provider organizations and early-stage start-ups on the transition to value-based care and health IT strategy.

Three different political systems have been proposed for the Teuchitlán culture with the site of Los Guachimontones having a role in all three systems. Phil Weigand and Christopher Beekman proposed the first in 1998 that consisted of a segmentary state model. In this model, there is a concentrated core and a broad surrounding hinterland. Within the core of the segmentary state, control is exerted through ceremonialism rather than political force.

Consequently, in conjunction with the variation of α, the Tweedie convergence theorem can be viewed as having a role in the genesis of such multifractals. The variation of α has been found to obey the asymmetric Laplace distribution in certain cases. This distribution has been shown to be a member of the family of geometric Tweedie models, that manifest as limiting distributions in a convergence theorem for geometric dispersion models.

The British doctrine at the time did not foresee the armoured division having a role in its own right and was assigned the traditional cavalry role. They would then deploy independent tank brigades equipped with the infantry tanks to operate with the infantry. German panzer and light divisions were equipped with the latest Panzer III and Panzer IV tanks, which could outgun all British tanks.Buell, Bradley, Dice & Griess (2002), p.

According to the Hindu, two men on a motorcycle wearing black shirts, jeans and helmets planted the bomb. Investigating authorities revealed that ammonium nitrate, sulphur and potassium were used to cause the low-intensity blast. A team of National Security Guards was deployed to assist the investigating authorities. Delhi Police had detained five persons at the Indira Gandhi International Airport whom they suspected of having a role in the blast.

Pete Fry designed the logo, and did graphics for the publication for a large portion of its existence. An article by Brian Salmi, predicting forthcoming riot violence was blamed for having a role in the 1994 Stanley Cup Riot. The paper, and Salmi were never charged. It was one of the first papers to carry Dan Savage's "Savage Love" column other than his home publication, The Stranger, based out of Seattle.

It offers advantages over other materials such as aluminium, although this usage has fallen out of favor due to magnesium's flammability. Magnesium is also often alloyed with aluminium or zinc to form materials with more desirable properties than any pure metal. Magnesium has many other uses in industrial applications, such as having a role in the production of iron and steel, and the production of titanium. Calcium also has many uses.

In addition to having a role in the 'election' of English Kings, it is often held that the witenagemots had the power to depose an unpopular king. However, there are only two occasions when this probably happened, in 757 and 774 with the depositions of kings Sigeberht of Wessex and Alhred of Northumbria respectively.Chadwick, Anglo-Saxon Institutions, pp. 362–63. The witan's powers are illustrated by the following event.

Nicomedes III was soon expelled by Mithridates VI, who restored upon the throne Ariarathes VII. However, Ariarathes VII objected to his father's assassin, and ally of Mithridates VI, Gordius, having a role in the government of Cappadocia. So Mithridates VI had Ariarathes VII killed in 101 BC. Mithridates VI then put onto the Cappadocian throne his own 9 year old son, Ariarathes IX of Cappadocia, with Gordius as the regent for the young king.

Cendrakasih began acting in her teens, at first on stage and later in film. JB Kristanto, in his catalogue of Indonesian films, lists her as having a role in S Waldy's Musafir Kelana (The Wanderer, 1953). The Indonesian film historian Misbach Yusa Biran, meanwhile, writes that Cendrakasih made her feature film debut Ali Joego's Oh, Ibuku (O, My Mother, 1955). Cendrakasih subsequently appeared in Gambang Semarang (Gambang from Semarang, 1955) alongside her mother.

In September, the Colonial Office announced independence day would be 6 March 1957. The opposition was not satisfied with the plan for independence, and demanded that power be devolved to the regions. Discussions took place through late 1956 and into 1957. Although Nkrumah did not compromise on his insistence on a unitary state, the nation was divided into five regions, with power devolved from Accra, and the chiefs having a role in their governments.

To be specific, it is found in the somata and dendrites of dopaminergic neurons in the ventral tegmental area (VTA) and the substantia nigra. Some studies implicate this pathway as having a role in attention deficiency and hyperactive behavior. Soluble guanylate cyclase contains a molecule of heme, and is activated primarily by the binding of nitric oxide (NO) to that heme. sGC is primary receptor for NO a gaseous, membrane-soluble neurotransmitter.

These elements have significantly affected political participation. Digital media is seen by many scholars as having a role in Arab Spring, and crackdowns on the use of digital and social media by embattled governments are increasingly common. Many governments restrict access to digital media in some way, either to prevent obscenity or in a broader form of political censorship. Over the years YouTube has grown to become a website with user generated media.

Benjamin Fairbanks was an 18th-century farmer and selectmen from Dedham, Massachusetts who received the lightest sentence of anyone ever convicted under the Sedition Act of 1798. Fairbanks was charged with having a role in erecting the liberty pole in Dedham, along with David Brown. Brown held the ladder while another, presumably Fairbanks, put up a seditious sign on it. When it appeared, Fisher Ames and the rest of Dedham's Federalist community were enraged.

This occurs because the female body will only take the step to begin puberty if there are available mates around. She will not waste energy on puberty if there is no possibility of finding a mate. In addition to GnRH, exogenous estradiol has recently implicated as having a role in the Vandenbergh effect. Utilizing tritium-labeled estradiol implanted in male mice, researchers have been able to trace the pathways the estradiol takes once transmitted to a female.

Moreover, in cases involving topical therapeutics, the role of MSM as an active agent, per se, versus its having a role in promoting skin permeation (in manner, akin to its solvent relative DMSO) must be characterized/controlled. The biochemical effects of supplemental methylsulfonylmethane are poorly understood. Some researchers have suggested that MSM has anti-inflammatory effects. The spectrum of biological effects of dimethyl sulfoxide (DMSO) and MSM differ, but those of DMSO may be mediated, at least in part, by MSM.

" The lack of graphics, poor interface and controls were seen as the reasons for the game's difficulty. However, the reviewers also noted most of it having a role in gameplay and the argument that the text-based graphics forces players to use their own imagination, making it more engaging. Weiner wrote, "[the game] may not look real, but once you're hooked, it feels vast, enveloping, alive. A micro-manager's dream, the game gleefully blurs the distinction between painstaking labor and creative thrill.

The map for the archaeology site of Los Guachimontones, Jalisco, Mexico Three different political systems have been proposed for the Teuchitlán Culture with the site of Los Guachimontones having a role in all three systems. Phil Weigand and Christopher Beekman proposed the first in 1998 that consisted of a segmentary state model. In this model, there is a concentrated core and a broad surrounding hinterland. Within the core of the segmentary state, control is exerted through ceremonialism rather than political force.

MAP3K12, otherwise known as DLK, can initiate coordinated signalling cascades that culminate in the phosphorylation of C-Jun N-terminal kinases or JNK. Several experiments have implicated this interaction as having a role in the developing mammalian nervous system. For example, neuronal migration and axon growth are critical components of neuronal development. DLK null mice have defects in neuronal migration, hypoplasia of several different axonal tracts and reduced axon number in various areas of the brain such as the cingulum and internal capsule.

On July 2, 2018, Davis confessed to having a role in the killing of Tupac after revealing he is dying of cancer. He went on to say he was the passenger in the white Cadillac on the night of the incident. He refused to name the other suspects in the car but confirmed that the shooter was Orlando Anderson, his nephew, and that it was out of retaliation for getting jumped at the MGM Grand earlier and the $1 million bounty by Puff Daddy.

Antagonists of the receptors cause synthesis and release of these neurotransmitters which promotes waking. H3Rs are mostly expressed on the histaminergic neurons of the CNS but can also be found in various areas of the peripheral nervous system. The H3R has been found in high densities in the basal ganglia, hippocampus and cortical areas which are all regions of the brain associated with cognition. The histaminergic system has been described as having a role in the pathophysiology of cognitive symptoms of diseases such as Alzheimer’s, schizophrenia and narcolepsy.

His reorganization has been credited as having a role in the French Revolutionary Army's victory in the Battle of Valmy (20 September 1792). Later, after the desertion (April 1793) of general Charles François Dumouriez, he was however arrested as an Orleaniste, being freed after the Thermidorian Reaction of 27 July 1794. He thenceforth spent some time in ballistic studies, which led him to the invention of the modern artillery shell. In 1795 he requested of the Committee of Public Safety reintegration in the army, a request which the Committee ignored.

Although a supporter of the Labour party, Clifford's approach in dealing with the Blair government was similar to that which he employed with Major's preceding Conservative government. The first instance of this was the story of Welsh Assembly leader Ron Davies. Then Clifford was accused by David Blunkett at the beginning of November 2005 of having a role in Blunkett's second resignation. This derived from claims made on behalf of a much younger woman, who had become involved with Blunkett, over Blunkett's business interests, which were published in The Times.

Stone credited the comments attributed to Haldeman in The Ends of Power as the source for his scenario. According to the political commentator Chris Matthews, Haldeman denied writing those words and said the theory of events actually belonged to DiMona. Matthews reported that Haldeman said he had no idea of what Nixon meant by the "whole Bay of Pigs thing" comments. Noting that Stone had implicated Nixon as having a role in planning a plot to kill Castro, Howard Rosenberg described it as "one of the most controversial themes of his movie".

In his capacity as Minister for Justice, O'Higgins established the Garda Síochána police force. His brother Thomas and nephews Tom and Michael were also elected TDs at various stages. Along with Arthur Griffith, Michael Collins and Eoin O'Duffy, O'Higgins is an important figure in Irish nationalist historiography, representing a more "conservative revolutionary" position when contrasted with republicanism. After having a role in the Irish War of Independence, he went on to defend the nascent Irish Free State, as part of the pro-Treaty side in the Irish Civil War.

After World War II ended, the Balli Kombëtar were defeated by Yugoslav and Albanian communists. The Ballists were so thoroughly discredited by their collaboration with the Nazis that there was no chance of them having a role in postwar Albania, though it took until 1945 to finish them off. Ironically, the Ballists' decision to work with the Nazis brought about the one thing they had sought to prevent – a Communist-dominated government. Balli Kombëtar fighters fled the Balkans to Austria, the United States, Australia, Switzerland and South America.

Her agent approached Ryan Murphy about her having a role in the series and he told the agent that she was the person he had in mind for Marie Laveau. Bassett watched the previous seasons of the series before meeting with Murphy and found the writing "wonderful" and the characters "so realized". Bassett's performance earned her a nomination for the Primetime Emmy Award for Outstanding Supporting Actress in a Miniseries or a Movie. She returned to the show for its fourth season American Horror Story: Freak Show, playing Desiree Dupree, a three-breasted woman.

Tension on the New York piers was mounting. ILA loyalists and many other longshoremen were at best suspicious of the IBL, which they viewed as a machine of the Waterfront Commission and a scab union—an organization of workers perceived as having a role in strike breaking. By early March 1954, the storm finally hit when Teamster boss David Beck was perceived as betraying the ILA by refusing to cross an IBL picket line. News spread and on piers up and down Manhattan, ILA longshoremen refused to touch Teamster deliveries.

Sasha Jenson (born January 12, 1964) is an American film and television actor known for his role in the 1993 hit film Dazed and Confused. He is also known for his role in the 1988 horror movie Halloween 4: The Return of Michael Myers, also Ghoulies II in 1988, and for having a role in the 1992 hit movie Buffy the Vampire Slayer. His most recent film is in the 2003 release Grind. Jenson starred in the television series Teen Angel as Jason, and made guest appearances on shows like NYPD Blue and Monsters.

Ecology has a complex origin, due in large part to its interdisciplinary nature. Ancient Greek philosophers such as Hippocrates and Aristotle were among the first to record observations on natural history. However, they viewed life in terms of essentialism, where species were conceptualized as static unchanging things while varieties were seen as aberrations of an idealized type. This contrasts against the modern understanding of ecological theory where varieties are viewed as the real phenomena of interest and having a role in the origins of adaptations by means of natural selection.

Through this pattern the faith grew exponentially through the efforts of women as each generation passed. Despite women having a role in the growing of the faith, Catharism was not completely equal, for example the belief that one's last incarnation had to be experienced as a man to break the cycle. This belief was inspired by later French Cathars, who taught that women must be reborn as men in order to achieve salvation. Another example was that the sexual allure of women impeded man's ability to reject the material world.

It is able to bind to and phosphorylate the histone H3 of chromatin in cancer cells, thereby having a role in the regulation of gene expression. This modification of histone H3 and the resulting involvement in gene expression regulation can be a cause of tumor cell proliferation. The pyruvate kinase activity of PKM2 can be promoted by SAICAR (succinylaminoimidazolecarboxamide ribose-5′-phosphate), an intermediate in purine biosynthesis. In cancer cells, glucose starvation leads to a rise in SAICAR levels and the subsequent stimulation of pyruvate kinase activity of PKM2.

However, as time has gone by, researchers such as Pessoa, generalized this concept with help from evidence of EEG recordings, and concluded that the amygdala helps an organism to define a stimulus and therefore respond accordingly. However, when the amygdala was initially thought to be linked to fear, this gave way for research in the amygdala for emotional processes. Kheirbek demonstrated research that the amygdala is involved in emotional processes, in particular the ventral hippocampus. He described the ventral hippocampus as having a role in neurogenesis and the creation of adult-born granule cells (GC).

The C-terminal of TREK-1 channels plays a role in the mechanosensitivity of the channels. In the neurons of the central nervous system, TREK-1 channels are important in physiological, pathophysiological, and pharmacological processes, including having a role in electrogenesis, ischemia, and anesthesia. TREK-1 has an important role in neuroprotection against epilepsy and brain and spinal cord ischemia and is being evaluated as a potential target for new developments of therapeutic agents for neurology and anesthesiology. In the absence of a properly functioning cytoskeleton, TREK-1 channels can still open via mechanical gating.

Christopher Randolph (born 1959 in Boston, Massachusetts) is an American actor known for providing the English voice for Hal "Otacon" Emmerich and Dr. "Huey" Emmerich in the Metal Gear Solid series. Prior to landing his role as Otacon, he auditioned for multiple parts, including Solid Snake. After David Hayter was recast from playing Snake in Metal Gear Solid V: Ground Zeroes, Randolph became the longest serving English voice actor in the franchise, having a role in all but one main Metal Gear Solid series game since 1998. He also writes, directs, and teaches acting.

One of the main suspects that was identified as potentially having a role in LeeAnna's disappearance was a man by the name of Matthew James Curtis, who was aged 24 at the time. In August 2003, Curtis was arrested for possession of child pornography. He was interrogated a number of times by the police about whether or not he had anything to do with LeeAnna's case. Due to his prior charges and his proximity to LeeAnna, authorities suspected that Curtis had played a role in the young girl's disappearance.

TRAAK is only expressed in neuronal tissue, and can be found in the brain, spinal cord, and retina, which suggests that it has a function beyond mechanotransduction in terms of neuronal excitability. The highest levels of TRAAK expression are in the olfactory system, cerebral cortex, hippocampal formation, habenula, basal ganglia, and cerebellum. TRAAK channels are mechanically activated when there is a convex curvature in the membrane that alters the channel’s activity. TRAAK channels are thought to have a role in axonal pathfinding, growth cone motility, and neurite elongation, as well as possibly having a role in touch or pain detection.

Geneticists studying these premature-aging syndromes propose that caretaker genes that determine cell fate also play a significant role in aging. Similarly, gatekeeper genes have been identified as having a role in aging disorders that exhibit mutations in such genes without an increased susceptibility to cancer. Experiments with mice that have increased gatekeeper function in the p53 gene show reduced cancer incidence (due to the protective activities of products encoded by p53) but a faster rate of aging. Cellular senescence, also encoded by a gatekeeper gene, is arrest of the cell cycle in the G1 phase.

As a result, an increased co-expression of multiple isoforms at demyelinating nodal sites in painful dental pulp. This isoforms of sodium channels may be a main factor in pain sensations due to their production of axonal excitability properties.Michael A Henry, et al, Unmyelinated nerve fibers in the human dental pulp express markers for myelinated fibers and show sodium channel accumulations, Neuroscience, Volume 169, Issue 4, 15 September 2010, Pages 1881-1887, ISSN 0306-4522, 10.1016/j.neuroscience.2010.06.044. Neuropeptides are increasingly being researched for having a role in molecular mechanisms involved with pain, including ion channels and inflammation.

It was established by the Community Justice (Scotland) Act 2016, replacing eight community justice authorities that were set up under the Management of Offenders etc (Scotland) Act 2005. The organisation will oversee the new local arrangements, which aims to provide a more effectively rehabilitation in the community, following convictions. As well as having a role in assisting people released from custody, it will also be concerned with the management of people convicted of crimes who are not sent to prison. Karyn McCluskey, who had been Director of the Violence Reduction Unit, was named chief executive in September 2016.

Javy López was named the MVP for having a role in each Atlanta victory. In Game 1, he snapped a 2–2 tie with a two-run single; in Game 5, he hit a home run, two doubles, and scored four runs; in Game 6, he singled and scored after being hit by a pitch; and in Game 7, he went two for four with a double, a home run, three RBIs, and scored three runs. Overall, he batted .545 (13 for 24) with eight runs scored, five doubles, two home runs and six RBIs in the Championship Series.

Though not having a role in the story, Sumner and Ruri are from the video games TR1: New Wave and New Vision and make a cameo appearance in episode 45, watching something launching into space; Ruri has the latest issue of ray=out in her pocket, and the two are apparently listening to a radio. The events surrounding Sumner take place a few years prior to that of the anime. They are also the main characters of the Eureka Seven: Gravity Boys and Lifting Girl prequel manga, which chronicles Sumner and Ruri's lives when they were Renton's age.

Carbon monoxide (CO) is a colorless, odorless, and tasteless flammable gas that is slightly less dense than air. It is toxic to animals that use hemoglobin as an oxygen carrier (both invertebrate and vertebrate) when encountered in concentrations above about 35 ppm, although it is also produced in normal animal metabolism in low quantities, and is thought to have some normal biological functions. In the atmosphere, it is spatially variable and short-lived, having a role in the formation of ground-level ozone. Carbon monoxide consists of one carbon atom and one oxygen atom, connected by a triple bond that consists of a net two pi bonds and one sigma bond.

The group is known for maintaining tight control over their career, heavily involving themselves since their debut in the production of their music and songwriting, as opposed to many Korean idol groups. G-Dragon is known as the member that is most heavily involved in the production of the group's materials, having a role in producing almost their entire discography spanning ten years, and credited as the main songwriter for the group's earlier hits such as "Lies", "Last Farewell", and "Day by Day". G-Dragon, T.O.P, and Taeyang also collaboratively wrote "Last Dance", with G-Dragon co-producing the song. Recurring themes in their lyrics deal with love and relationships.

In early 2007, Samuel Quero Martínez, Rufino Aguilar Quero and Robert Luís Arreola, residents of Mitla, denounced the sacking of the museum and sale of its pieces, with the government of Oaxaca being suspected of having a role in the affair. Formal charges were filed in 2008. The dean of UDLA has denied the charges, and denies that the pieces were in the school's responsibility when they were found to be missing, but rather the property of INAH as "property of the nation". The dean claims that the university is not fit to manage such a museum and handed over the management of it to INAH.

Shona is arrested for helping him escape but denies having a role in his escape plot and she is released from custody shortly afterwards. In July 2019, David is framed for stealing Audrey's money and is sentenced to four months in prison, while Nick, the person who really stole the money, is sentenced to 2 years imprisonment but receives a suspended sentence. In October that same year, David is due to be released in a few weeks, in the lead up to his release he befriends a prisoner named Abe. Shortly after he goes to take his medication in the medical wing, to the horror of David, he sees Josh.

Little is yet been found about Laneham having a role in civil administration, but it is known that at least one major 'trial' was held in the village. Thomas Hancock was the Puritan vicar of Headon from 1605 to 1623, arriving from Elkesley. In 1620 he was fined "6d for riot", at a special sessions in Laneham to try 26 people indicted for riotous assault. Hancock had something of a record for challenging the establishment, having also been one of the Puritan curates sheltered by the Brewsters at Scrooby in the 1690s when he had conducted the apparently illegal wedding of another cleric, Robert Southworth.

Oral tolerance is the process by which the immune system is prevented from responding to antigen derived from food products, as peptides from food may pass into the bloodstream via the gut, which would in theory lead to an immune response. A paper published in Nature in 2012 has shed some light on the process and implicated goblet cells as having a role in the process. It was known that CD103-expressing dendritic cells of the lamina propria had a role to play in the induction of oral tolerance (potentially by inducing the differentiation of regulatory T cells), and this paper suggests that the goblet cells act to preferentially deliver antigen to these CD103+ dendritic cells.

In October 2017, actor Bruno Langley, who portrayed Todd Grimshaw, was faced with allegations of sexual assault by two women who alleged that he groped them at a nightclub some years previously. Following an internal investigation, Coronation Street announced that Langley's contract with the show had been terminated, and consequently, Todd Grimshaw would be written out of the programme towards Christmas. Langley's sacking came at an unfortunate time. The character of Todd was set to become integral to a storyline involving his long-term romantic partner Billy Mayhew (Daniel Brocklebank) being outed as having a role in the death of former character Susan Barlow sixteen years previously; Susan was the mother of Todd's business partner Adam Barlow (Samuel Robertson).

During the 2007 Gubernatorial campaign Democratic candidate Steve Beshear was accused by his opponent, then-Governor Ernie Fletcher, of having a role in the collapse of Kentucky Central. Beshear's law firm, Stites & Harbison, was hired to serve as general counsel to liquidator Donald Stephens, who was the state insurance commissioner. However, Stites & Harbison already represented the Bank of Louisville, whose holdings included millions of dollars of securities put up as collateral for a loan connected to Kentucky Central in a complicated real estate deal. Stephens asked another law firm in 1995 to look into allegations that Stites & Harbison had a conflict of interest representing the Office of Insurance while continuing to represent the Bank of Louisville.

University of Toronto psychology professor Jordan Peterson, well- known as an admirer of Jung’s work, uses Jungian terminology but reconfigures it into a model that divides the psychological world into the domains of nature and culture. The Great Father of culture is an archetypal force that shapes the potential of chaos into the actuality of order. In this framework, the persona would be the aspect of the personality that has been adapted to culture, more specifically to the social dominance hierarchy. People who refuse to submit to this social discipline or carry the responsibility inherent in having a role in the world remain as undifferentiated potential, known in more Jungian terms as peter pan syndrome, or the negative aspect of the puer aeternus.

Israel Keyes has been proposed as having a role in Maddy's disappearance, however Keyes' MO usually included theft from his victims; nothing was known to be stolen from Maddy's campsite. There were multiple items of value left behind in plain sight at Maddy's campsite, including a purse, camera, gasoline, expensive motorbike equipment and liquor; this is contrary to Keyes' MO of stealing from his victims. Hogsback lake is a straight 33 hour drive from Anchorage, Alaska, where Keyes lived, and in a different country; making travel quite inconvenient for Israel. However, a few days after Maddy's disappearance, on 2 June 2011, Keyes was known to have flown from Alaska to Chicago, rented a car and drove almost 1,000 miles to Vermont with the intent of committing murder.

The colour centre is a region in the brain primarily responsible for visual perception and cortical processing of colour signals received by the eye, which ultimately results in colour vision. The colour centre in humans is thought to be located in the ventral occipital lobe as part of the visual system, in addition to other areas responsible for recognizing and processing specific visual stimuli, such as faces, words, and objects. Many functional magnetic resonance imaging (fMRI) studies in both humans and macaque monkeys have shown colour stimuli to activate multiple areas in the brain, including the fusiform gyrus and the lingual gyrus. These areas, as well as others identified as having a role in colour vision processing, are collectively labelled visual area 4 (V4).

The cerebellum is highlighted red The cerebellum is known to play a part in correcting movement and in fine-tuning the motor agility found in procedural skills such as painting, instrument playing and in sports such as golf. Damage to this area may prevent the proper relearning of motor skills and through associated research it has more recently been linked to having a role in automating the unconscious process used when learning a procedural skill. New thoughts in the scientific community suggest that the cerebellar cortex holds the holy grail of memory, what is known to researchers as "the engram" or the biological place where memory lives. The initial memory trace is thought to form here between parallel fibers and Purkinje cell and then travel outwards to other cerebellar nuclei for consolidation.

Concerns were once again raised in 2020, this time by a senior Conservative MP, about CGN having a role in the UK's infrastructure, following the UK government's decision to exclude another Chinese firm, Huawei from the UK's 5G infrastructure over espionage concerns. Following this, nuclear industry executives confirmed that the Bradwell B project is also of major concern, especially within the Conservative government. The Financial Times reported on 6 August 2020 that a group of 'rebel Conservative MPs' are now turning their attention to the Bradwell B project as well as CGN's involvement in the Sizewell C project, following success at reversing the government's stance on Huawei. The article claimed that that at a private meeting with MPs last month, CGN’s activities were raised with the United States Secretary of State, Mike Pompeo.

After being sworn in as premier, Wynne quickly became embroiled in the Ontario power plant scandal, which had developed under the administration of her predecessor, Premier Dalton McGuinty. Opposition parties accused Wynne of having a role in the McGuinty government's costly decision to cancel the construction of gas plants in Mississauga and North-East Oakville in 2011, when she was co-chair of the Liberal campaign. Wynne denied that she was involved in the gas plant meetings or in the decision to cancel the plants, and asked the auditor general to investigate the cost of cancelling the plants. After months of investigation, the auditor general released their report on the gas plants in October 2013, suggesting the cancellation of both gas plants could cost taxpayers as much as $1.1 billion.

Versace also planned a Spring collaboration with the company that was only available in countries with online sales. Similar to previous collaborations, Versace agreed to let H&M; use its name for a previously agreed-upon sum, without actually having a role in the design process. In November 2011, H&M; announced a collaboration plan with Marni, that launched in March 2012. The campaign was directed by director Sofia Coppola. Trompe-l'œil printed viscose jersey dress by Maison Martin Margiela for H&M;, 2012 Lana Del Rey was the face of the fully plotted music video for the 2012 global summer collection, where she also sang a cover of "Blue Velvet". On 4 October 2012, Japanese Vogue editor Anna Dello Russo launched an accessories collection at H&M; as Paris Fashion Week drew to an end.

Its physiological role for fish, bacterial cell or insect is not known. However, in ferns it is thought to offer protection from insects while studies have shown that thiamine hydrolase (thiaminase type 2) which was originally thought to be involved solely in the degradation of thiamine has actually been identified as having a role in thiamine degradation with the salvage of the pyrimidine moiety where thiamin hydrolysis product N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine is transported into the cell and deformylated by the ylmB-encoded amidohydrolase and hydrolyzed to 5-aminoimidazole ribotide. It was first described as the cause of highly mortal ataxic neuropathy in fur producing foxes eating raw entrails of river fish like carp in 1941. It is also known as the cause of cerebrocortical necrosis of cattle and polioencephalomalasia of sheep eating thiaminase containing plants.

Although in experiments on synaptosomes, α-LTX triggered non-calcium dependent exocytosis of vesicles containing acetylcholine, glutamate and GABA,Role of calcium in neurotransmitter release evoked by alpha-latrotoxin or hypertonic sucrose - Khvotchev et al. both glutamate and GABA have been ruled out as the sole neurotransmitters responsible for emodepside's action) which then acts on the post-synaptic membrane (i.e. the pharyngeal/muscle membrane) of the nematode, having an inhibitory effect thereby either inducing paralysis or inhibiting pharyngeal pumping, both of which ultimately result in the death of the organism. Diagram Mutational studies involving LAT-1 knockout and LAT-2 gene deletion mutants have revealed that the role of latrophilin receptors in the different tissues that they are expressed differs between subtypes, with LAT-1 being expressed in the pharynx of C.elegans (thereby modulating pharyngeal pumping) and LAT-2 having a role in locomotion.

Kim Won- hong rose to prominence in 2003, as he was appointed commander of the Military Security Command (the North Korean army's intelligence unit) following the death of General Won Ung-hui, who had been heading it since 1990. In April 2009, Kim was promoted to General and then migrated to the KPA General Political Bureau's Department, at the same time when Kim Jong-il reportedly put Kim Jong-un in charge of the Ministry of State Security to which the Military Security Command is affiliated. Kim was also made a member of the Party's Central Committee and Central Military Commission in September 2010 and was reported to having a role in ensuring Kim Jong-un's succession. After Kim Jong-il's death and acting head of State Security Department, U Tong- chuk's purge, Kim Won-hong appeared as one of Kim Jong-un's most trusted and supporting generals.

The Senate Intelligence Committee eventually discovered that President Bush and his advisers heavily exaggerated the claims of weapons of mass destruction in Iraq and terrorist ties to Al Qaeda which were not validated by U.S. intelligence units. Since this scandal, Perle has made several attempts to reduce his alleged involvement in the war efforts stating: "Huge mistakes were made, and I want to be very clear on this: They were not made by neoconservatives, who had almost no voice in what happened..." In an interview he gave Vanity Fair that was excerpted in an article appearing in the 4November 2006 Los Angeles Times, he denied having a role in the planning of the war. He is reported to have told Vanity Fair, "I'm getting damn tired of being described as an architect of the war." This is not congruent with his signing of the PNAC letter in 1998.

In the Christmas Special, Mr Chinnery, who fears that he's on the verge of losing his sanity, told Bernice the story of how his great-grandfather Edmund Chinnery, the foremost vet of his time, was cursed to have any animal he touched "meet a dreadful end" and that his descendants would carry the curse after him. Bernice reassured him that there was no such thing as curses and that he, the doctor who first had the curse and his ancestor had had accidents similar to the curse primarily because they were scared of the curse and thought that they had it. She then told him to go and do his next job without any fear of the curse. He does not appear at all in Series 3, but does make an appearance in the film, The League of Gentlemen's Apocalypse, treating a giraffe and having a role in the film's climax.

Less than two weeks later, an article in The Seattle Daily Times hinted that then-recent Seattle mayor George F. Cotterill may have fired R.H. Ober as Superintendent of Buildings because of the latter's safety- related rejection of permits for the Grand."Former Mayor Will Be Asked by Committee to Explain Removal of Ober as Superintendent of Buildings", The Seattle Daily Times, February 3, 1917, p.11. (There was a long-running feud between the Times and Cotterill, in which the newspaper "consistently ridiculed Cotterill and his positions.") Levy had boasted in an advertisement about having a role in getting Ober removed, and other city officials may have felt intimidated by that; on the other hand, Fire Chief Frank L. Stetson asserted that the Grand had appeared no more dangerous than "other buildings of its type" and that the changes to the building that Ober had wanted had, indeed, ultimately occurred.

During evolution, hummingbirds have adapted to the navigational needs of visual processing while in rapid flight or hovering by development of an exceptionally dense array of retinal neurons allowing for increased spatial resolution in the lateral and frontal visual fields. Morphological studies showed that neuronal hypertrophy, relatively the largest in any bird, exists in a brain region called the pretectal nucleus lentiformis mesencephali (or nucleus of the optic tract in mammals) responsible for refining dynamic visual processing while hovering and during rapid flight. The enlargement of this brain region responsible for visual processing indicates an enhanced ability for perception and processing of fast-moving visual stimuli which hummingbirds encounter during rapid forward flight, insect foraging, competitive interactions, and high-speed courtship. A study of broad-tailed hummingbirds indicated that hummingbirds have a fourth color-sensitive visual cone (humans have three) that detects ultraviolet light and enables discrimination of non-spectral colors, possibly having a role in courtship displays, territorial defense, and predator evasion.

Through text mining, TMEM143 is shown to have interactions with seven different proteins in humans: Zinc finger protein 541 (ZNF541), DNA-damage inducible 1 homolog 2 (DD12), Paraneoplastic Ma antigen family-like 2 (PNMAL2), Kelch-like 31(JLHL31), Chromosome 14 open reading frame 28 (C14orf28), Chromosome 14 open reading frame 28 (TRIN71), and Cytoplasmic polyadenylation element binding protein 2 (CPEB). ZNF541 and PNMAL2, in relation to TMEM143, have been documented as having a role in the allelic loss of q13.3 of chromosome 19. This loss results in documented cases of malignant gliomas, neuroblastomas, and ovarian carcinomas, all suggesting a tumor suppression gene or genes in this region. While TMEM143 is not directly referred to in research in this area, it is present in this region on the chromosome, indicating a potential functional role in humans. Interactions between TMEM143 and DD12, JLHL31, C14orf28, TRIN71, and CPEB (in humans) have been documented through microarray data.

The FIA keenly tracked the whereabouts of Murtaza Bhutto in Syria, and successfully limited the influence of his al-Zulfikar group. In 1985, the FIA's undercover operation busted the drug trade, with the illicit trade leaders and their culprits apprehended by the FIA. Known as the "Pakistan League Affair", the FIA effectively put an end to the illicit drug trade with the arrest of the gang's key drug lord. From 1982 to 1988, the FIA launched a series of investigations and probes against Pakistan Communist Party leader Jam Saqi and aided the court proceedings relating to its findings. In 1986, the FIA successfully infiltrated the terrorist group responsible for hijacking Pan Am Flight 73, and quickly detained the Libyan commercial pilot suspected of having a role in the hijack. After securing voting plurality in 1993 Pakistani general elections, Prime Minister Benazir Bhutto further widened the scope of FIA, making FIA akin to Inter-Services Intelligence (ISI) in the intelligence community.

He admonished his soldiers not for the murder of the civilian population but for the chaotic way in which it was undertaken, particularly the premature taking of hostages and random measures. He ordered his troops to focus on Jews and Communist civilians, remarking that Communists were Jews that needed capture anyway; in order to improve relations with Ukrainians, even in cases of Ukrainian sabotage, local Jews were targeted for reprisal.Nazi empire-building and the Holocaust in Ukraine, Wendy Lower pages 54-55 UNC Press 2006 Thomas J. Laub presents a more complicated picture of Stülpnagel. According to Laub, while having a role in the Final Solution by their part in the deportation of Jews (although reluctantly, possibly by trying to avoid seeing the consequences of the deportation, which they preferred over mass shootings), both Carl-Heinrich and his cousin Otto (also his predecessor in France) disagreed with the regime's extreme aspects, including its racial agenda, and viewed the war as a traditional struggle between nation states rather than an ideological struggle.