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73 Sentences With "folding to"

How to use folding to in a sentence? Find typical usage patterns (collocations)/phrases/context for "folding to" and check conjugation/comparative form for "folding to". Mastering all the usages of "folding to" from sentence examples published by news publications.

Remove from heat, and add egg mixture, gently folding to completely incorporate.
While they waited, the immigrants turned to paper folding to pass the time.
South Korea, on the other hand, is worried about the political ramifications of folding to Washington's demands.
They also see the tariffs as helping to ward off political criticism that Mr. Trump is folding to China.
Suddenly the painstaking effort I had taken to pack a suit and tie, carefully folding to avoid wrinkles, felt amateurish.
It took about 40 years after the invention of the printing press for paper folding to commonly create smaller, cheaper volumes.
Our success here will be limited but still far more effective and virtuous than folding to Trump's coercion and losing our political voice.
On Wednesday, Trump contended his decision to ask his Commerce Department to find a way to aid ZTE did not constitute "folding" to China's suggestions.
Others argue that the firing of Gillis was less about folding to political correctness and more about how Gillis would fit into the culture of SNL.
But he used paper and origami folding to create the masks, and then added shellac, acrylic paint and polyurethane varnish to give them a final gothic appearance.
At Harvard University, engineers turned to kirigami — the Japanese art of paper cutting, rather than foldingto create artificial snakeskin that enables a soft robot to crawl forward.
Opponents have argued that the pope risked setting a terrible precedent by folding to an authoritarian power with a record of human rights abuses and persecution of religious groups.
DeepMind believes that the same principle will apply to science and health care, with deep-learning techniques helping to improve the accuracy and efficiency of everything from protein-folding to radiography.
His advisers have been working for months to secure an agreement strong enough to dodge criticism from both Democrats and Republicans that Mr. Trump is folding to America's biggest economic competitor.
No more empty rhetoric, no more folding to political pressure, no more accepting by inaction this fundamental injustice that stains the future of the greatest republic in the history of the world.
While RAGA is focused on winning elections and the hearts and minds of voters, DAGA is focused on disregarding the rule of law and folding to the demands of extreme special interest groups.
Sanders' and Biden's campaigns criticized Harris' plan, with the former accusing her of folding to the interests of the health insurance industry and the latter saying she was undercutting the Affordable Care Act.
Many people tend to agree, even in the moment, that these behaviors are foul, and the companies folding to them under pressure are too weak-willed and image-conscious to take a proper stand.
With earnings improving, the dollar weakening and margins rising, Dwyer argued that rather than folding to sell-off pressure if the market dips, investors should keep in mind the global factors that could play out in their favor.
Eventually, self-teaching systems will be used to solve more pressing problems, such as protein folding to conjure up new medicines and biotechnologies, figuring out ways to reduce energy consumption, or when we need to design new materials.
Twist and then fold the large loop in half to make a double loop, and repeat this process about 4-5 times: stretching the loop to arms length, twisting and folding to develop many thin "strings" within the loop.
READ: Macron keeps folding to the yellow vest protesters — but it might not be enough In a statement, Five Star said the yellow vests had many commonalities with the anti-establishment party, and that their two movements would soon hold another meeting in Rome.
Continuing the conceptual ethos of the label they run together along with OYE Records' Delfonic, Money $ex Records, the new album is chock full of dusty, hip-hop inflected deep house music that's danceable without folding to any conventional molds you'd find in dance music.
Those hopes took a big hit on Monday when Caruana, considered America's best hope in decades for a world championship title, lost his final match in the Moscow tournament, folding to Sergey Karjakin of Russia and missing the chance to advance to the event in New York.
READ: Macron keeps folding to the yellow vest protesters — but it might not be enough The attack was the latest in a string of Islamist atrocities on French soil in recent years, that has killed more than 240 people since the Charlie Hebdo attack of January 2015.
The other uses a swept wing or axial folding to produce something like a fuselage extending out of leading edge of the wing.
Slow-playing is deceptive play in poker that is roughly the opposite of bluffing: checking or betting weakly with a strong holding, attempting to induce other players with weaker hands to call or raise the bet instead of folding, to increase the payout.
In a September 2020 feature in the New Yorker, David Baker stated that the cancer drug Neoleukin-2/15, described in a January 2019 paper by the Rosetta@home researchers, would begin human clinical trials "later this year". Rosetta@home also contributed to this research with "forward folding" to validate designs.
Apart from above, a range of speciality tissues are also manufactured to be used in the packing industry. These are used for wrapping/packing various items, cushioning fragile items, stuffing in shoes/bags etc. to keep shape intact or, for inserting in garments etc. while packing/folding to keep them wrinkle free and safe.
An Escherichia coli-based open cell-free synthesis (OCFS) allows the synthesis of proteins containing site-specifically incorporated non-natural amino acids and has been optimized for predictable high-yield protein synthesis and folding. The absence of a cell wall allows the addition of non-natural factors to the system to manipulate transcription, translation and folding to provide precise protein expression modulation.
Consequences can also be played in a drawing version, sometimes known as picture consequences, where the first player draws the head, passes it unseen (by means of folding) to the second player who draws the body, then on to the third player who draws the legs. The composite person or creature is then revealed to all by unfolding the paper.
After the disc becomes tri-layered, it undergoes growth and folding to transform it from disc to cylinder shaped. The layer of ectoderm and mesoderm in the dorsal axis grow ventrally to meet at the midline. Simultaneously, the cephalic (head) and caudal (tail) ends of these layers of the disc fold ventrally to meet the lateral folds in the center. The meeting of both axis at the center form the umbilical ring.
The wings and stabilators are modified for folding to maximise the number of aircraft the carrier can accommodate and to allow ease of movement on deck. The aircraft is outfitted with more powerful turbofan engines to increase thrust-to-weight ratio, as well as an in-flight refuelling probe. The Su-33 sports canards that shorten the take-off distance and improve manoeuvrability, but have required reshaping of the leading edge root extensions (LERX).
I-motifs are particularly useful due to their unique sensitivity to changes in acidity near physiological pH. A study at the University of Bonn used I-motif folding to tighten and loosen a ring of DNA. A circular ring of DNA was synthesized, with certain regions of C-rich DNA. At a pH of 5, these regions contracted to form i-motifs, tightening the ring in a fashion similar to closing a trash bag.
Recently-deposited sediments are normally mechanically weak and prone to remobilization before they become lithified, leading to folding. To distinguish them from folds of tectonic origin, such structures are called synsedimentary (formed during sedimentation). Slump folding: When slumps form in poorly consolidated sediments, they commonly undergo folding, particularly at their leading edges, during their emplacement. The asymmetry of the slump folds can be used to determine paleoslope directions in sequences of sedimentary rocks.
The idea of using protein design to accomplish the same goals as DNA origami has surfaced as well. Researchers at the National Institute of Chemistry in Slovenia are working on using rational design of protein folding to create structures much like those seen with DNA origami. The main focus of current research in protein folding design is in the drug delivery field, using antibodies attached to proteins as a way to create a targeted vehicle.
Physiological serpin polymers are thought to form via domain swapping events, where a segment of one serpin protein inserts into another. Domain-swaps occur when mutations or environmental factors interfere with the final stages of serpin folding to the native state, causing high-energy intermediates to misfold. Both dimer and trimer domain-swap structures have been solved. In the dimer (of antithrombin), the RCL and part of the A-sheet incorporates into the A-sheet of another serpin molecule.
Some pen guns are not designed to fire regular cartridges, but rather blank cartridges, signal flares or tear gas cartridges. In the United States, pen guns that can fire bullet or shot cartridges and do not require a reconfiguration to fire (e.g., folding to the shape of a pistol) are federally regulated as an Any Other Weapon (Title II). They require registration under the National Firearms Act and a tax in the amount of five dollars is levied.
Though the North Atlantic was opening, a land connection appears to have remained between North America and Europe since the faunas of the two regions are very similar. India began its collision with Asia, folding to initiate formation of the Himalayas. It is hypothesized that the Eocene hothouse world was caused by runaway global warming from released methane clathrates deep in the oceans. The clathrates were buried beneath mud that was disturbed as the oceans warmed.
In kinetic partitioning, Hsp70s repetitively bind and release substrates in cycles that maintain low concentrations of free substrate. This effectively prevents aggregation while allowing free molecules to fold to the native state. In local unfolding, the binding and release cycles induce localized unfolding in the substrate, which helps to overcome kinetic barriers for folding to the native state. Ultimately, its role in protein folding contributes to its function in signal transduction, apoptosis, protein homeostasis, and cell growth and differentiation.
Some pen guns are not designed to fire regular cartridges, but rather blank cartridges, signal flares or tear gas cartridges. In the United States, pen guns that can fire bullet or shot cartridges and do not require a reconfiguration to fire (e.g., folding to the shape of a pistol) are federally regulated as an Any Other Weapon (Title II). They require registration under the National Firearms Act and a tax in the amount of $200 to manufacture or $5 to transfer is levied.
Recombinant expression of protein in Escherichia coli often results in the formation of insoluble protein aggregates called inclusion bodies. These protein bodies require refolding in vitro once extracted from E.coli cells by strong detergent. Proteins are thought to unfold during the solubilization process, and subsequent removal of detergent by dilution of analysis allows their refolding. Both folding enhancers and aggregation suppressors are often employed during the removal of denaturant to facilitate folding to the native structure and to prevent aggregation.
Much of the eastern movement is due to major strike-slip faults. These strike-slip faults, along with the other faults in Tibet could still be interpreted as on a plate margin though. True intraplate deformation occurs farther north in areas such as Mongolia or the Tian Shan mountains. These areas display true intraplate deformation because there is still much faulting and folding to accommodate some of the crustal shortening from the India/Eurasia collision hundreds of kilometers away from the plate margin.
In 1893, Indian civil servant T. Sundara Rao published Geometric Exercises in Paper Folding which used paper folding to demonstrate proofs of geometrical constructions. This work was inspired by the use of origami in the kindergarten system. This book had an approximate trisection of angles and implied construction of a cube root was impossible. In 1936 Margharita P. Beloch showed that use of the 'Beloch fold', later used in the sixth of the Huzita–Hatori axioms, allowed the general cubic equation to be solved using origami.
The dead time is the time between the end of mixing the two solutions and the beginning of observation of the kinetics of the reaction. The usual dead time of a stopped flow apparatus is 1–2 milliseconds but some new devices have been developed that have dead times of 0.3–0.6 ms. A stopped-flow instrument coupled to either a circular dichroism spectrometer or a fluorescence spectrometer is often used in the field of protein folding, to observe rapid unfolding and/or refolding of proteins.
The book consists of six chapters, the first of which introduces the problem, sets it in the context of the investigation of the mathematical strength of straightedge and compass constructions, and introduces one of the major themes of the book, the relegation of paper folding to recreational mathematics as this sort of investigation fell out of favor among professional mathematicians, and its more recent resurrection as a serious topic of investigation. As a work of history, the book follows Hans-Jörg Rheinberger in making a distinction between epistemic objects, the not-yet-fully-defined subjects of scientific investigation, and technical objects, the tools used in these investigations, and it links the perceived technicality of folding with its fall from mathematical favor. The remaining chapters are organized chronologically, beginning in the 16th century and the second chapter. This chapter includes the work of Albrecht Dürer on polyhedral nets, arrangements of polygons in the plane that can be folded to form a given polyhedron, and of Luca Pacioli on the use of folding to replace the compass and straightedge in geometric constructions; it also discusses the history of paper, and paper folding in the context of bookbinding.
The process of folding begins when the cells in the central region of the neural plate, the medial hinge point cells, bind to the notochord beneath them. This creates a central anchoring point for the process of folding to occur, and subsequently creates the neural groove. As the neural folds continue to extend, dorsolateral hinge points form, allowing the folds to curve into a tube-like structure. When the peaks of the folds (known as the neural crest regions) touch, they merge and involute, creating the neural tube beneath the newly formed epidermal layer.
Common protein design programs use rotamer libraries to simplify the conformational space of protein side chains. This animation loops through all the rotamers of the isoleucine amino acid based on the Penultimate Rotamer Library. In protein design, the target structure (or structures) of the protein are known. However, a rational protein design approach must model some flexibility on the target structure in order to increase the number of sequences that can be designed for that structure and to minimize the chance of a sequence folding to a different structure.
There are a number of ways that RPTP catalytic activity can be regulated (for reviews, see ). Dimerization of identical RPTP proteins at the cell surface leaves the PTP domains either in an open active conformation, as in the case of PTPmu and LAR, or in an inhibited conformation that leaves the catalytic domain inaccessible, in the case of CD45, PTPalpha, and PTPzeta/beta. The binding of different parts of the protein with itself (ex. by folding to interact with itself), known as intramolecular interactions, can affect the activity of RPTPs.
In contrast to the Central Eastern Alps north of the Periadriatic Seam, the geology of the Southern Alps is not characterized by nappes. Neither are high grade metamorphic rocks common in the region. The Southern Alps are tectonically characterized by large scale thrusting and folding to the south, the dominant vergence (direction of fold asymmetry) in the region is southward. As is also the case in the southern foreland of the Pyrenees, thrusts in the Southern Alps are oriented along listric fault planes with relatively shallow decollement horizons.
In local unfolding, the binding and release cycles induce localized unfolding in the substrate, which helps to overcome kinetic barriers for folding to the native state. Ultimately, its role in protein folding contributes to its function in signal transduction, apoptosis, protein homeostasis, and cell growth and differentiation. Hsc70 is known to localize to the cytoplasm and lysosome, where it participates in chaperone-mediated autophagy by aiding the unfolding and translocation of substrate proteins across the membrane into the lysosomal lumen. Through this pathway, Hsc70 also contributes to the degradation of the proapoptotic BBC3/PUMA under normal conditions, thus conferring cytoprotection.
In 1845, Edwin Hill and Warren De La Rue were granted a British patent for the first envelope-making machine. The "envelopes" produced by the Hill/De La Rue machine were not like those used today. They were flat diamond, lozenge (or rhombus)-shaped sheets or "blanks" that had been precut to shape before being fed to the machine for creasing and made ready for folding to form a rectangular enclosure. The edges of the overlapping flaps treated with a paste or adhesive and the method of securing the envelope or wrapper was a user choice.
In kinetic partitioning, Hsp70s repetitively bind and release substrates in cycles that maintain low concentrations of free substrate. This effectively prevents aggregation while allowing free molecules to fold to the native state. In local unfolding, the binding and release cycles induce localized unfolding in the substrate, which helps to overcome kinetic barriers for folding to the native state. Ultimately, its role in protein folding contributes to its function in signal transduction, apoptosis, protein homeostasis, and cell growth and differentiation. In addition to the process of protein folding, transport and degradation, this Hsp70 member can preserve the function of mutant proteins.
A variant of the Mini-Beryl is also offered with a MIL-STD-1913 Picatinny rail instead of the standard rear sight; a simple auxiliary rear sight is built into the rail. The standard rear sight and front post are provided with luminescent dots to assist aiming in poor light conditions. The weapon's gas block is longer than that of the Onyks and it features internal threading that is used to secure the muzzle device in place. The Mini-Beryl has a twin-strut stock folding to the right-hand side of the receiver; the butt-plate is rubber.
One factor that limit broad applicability of self-folding polymer films is the manufacturing cost. Actually, polymer can be deposited by spinning and dipping coating at ambient conditions, the fabrication of polymer self-folding films is substantially cheaper than fabrication of inorganic ones, which are produced by vacuum deposition. In another word, there is no method, which is cheap and large- scale production of self-folding polymer films that substantially limits their application. To solve these issues, the future research must be focused on deeper investigation of folding to allow design of complex 3D structures using just 2D shapes.
Because of the property of Ero1p to transfer electrons directly to molecular oxygen via a flavin-dependent reaction, its activity may produce reactive oxygen species (ROS). In bacteria, this problem is solved by coupling oxidative folding to the respiratory chain. There, the reduction of molecular oxygen to water is carried out by a complex series of proteins, which catalyse this reaction very efficiently. In eukaryotes, the respiratory chain is separated from oxidative folding since cellular respiration takes place in the mitochondria and the formation of disulfide bonds occurs in the ER. Because of this, there is much more risk that ROS are produced in eukaryotic cells during oxidative folding.
The team did play both of its two preseason games on the road before folding. To balance out the divisions, the easternmost-West Division team, the Winnipeg Blue Bombers, moved to the East Division to take the Alouettes' place (along with this, the "cross-over rule" for the playoffs was scrapped and until 1997). The CFL held a dispersal draft for the Alouettes players. Some of the players left out of work by the team's demise (both on the Alouettes and players on other CFL teams who were cut to make room for former Alouettes) played in the NFL as replacement players during another players' strike later that year.
One of these techniques is 'wet- folding,' the practice of dampening the paper somewhat during folding to allow the finished product to hold shape better. Variations such as modular origami, also known as unit origami, is a process where many origami units are assembled to form an often decorative whole. Complex origami models normally require thin, strong paper or tissue foil for successful folding; these lightweight materials allow for more layers before the model becomes impractically thick. Modern origami has broken free from the traditional linear construction techniques of the past, and models are now frequently wet- folded or constructed from materials other than paper and foil.
Most basically, applications use code folding to outline source code, collapsing each block to a single line. This can be only top-level blocks like functions and classes, nested blocks like nested functions and methods, or all blocks, notably control-flow blocks. This allows one to get an overview of code, easily navigating and rearranging it, and to drill down into more detail as needed, without being distracted by other code. Viewing-wise, this allows one to quickly see a list of all functions (without their bodies), while navigation-wise this replaces extensive paging past long functions – or searching for the target – with going directly to the next function.
Later in the season, FSN Pittsburgh agreed to pick up the remaining games; Erie, Pennsylvania-based Image Sports Network was also involved with the league. Eight teams participating in the league in 2007 did not return for the 2008 season, including the 2007 champion Lakeland Thunderbolts. The AIFA became the third league since 2004 (excluding the folded WIFL and NIFL before its folding) to lose its standing champion (the 2004 NIFL champion Lexington Horsemen left to join the newly created UIF and later were in af2, and the 2006 champion Billings Outlaws also left to join two years later). However, nine teams signed on to begin play in 2008, and the league created a Western Conference.
Many rock figures and small valleys with steep vertical slopes have formed over hundreds of millions of years as a result of the natural processes of erosion, denudation, growth of mosses and lichens, and other natural factors. The formation of the Belogradchik Rocks started during the Permian period, about 230 million years ago, when the tectonic cycle was folding to create the Balkan Mountains and elevating the region of Belogradchik. Later, during the Triassic period, the region became the floor of a shallow sea. At the same time, the destruction of the earlier Paleozoic rocks formed enormous quantities of gravel, sand and clay, which were deposited by the rivers into the sea basin.
It is documented in many cases that faulting may develop from detachment folding or through the kinematic mechanisms involved with folding.Bowsworth, W. (1983) Foreland deformation in the Appalachian Plateau, central New York: the role of small-scale detachment structures in regional overthrusting, Journal of Structural Geology, 6, 1-2, 73-81 In general, faulting may occur during fault slip and detachment folding in two ways. Firstly, faulting may be induced when progressive folding or tightening of a folded limb reaches its maximum fold geometry resulting in a transition from folding to shearing. Secondly, it has been suggested a fault may propagate into the anticlinal core if material flow and accommodation space are not at equilibrium.
ERAD normally removes misfolded ER proteins to the cytosol for their destruction by cytosolic proteasomes. Dislocation of RTA requires ER membrane-integral E3 ubiquitin ligase complexes, but RTA avoids the ubiquitination that usually occurs with ERAD substrates because of its low content of lysine residues, which are the usual attachment sites for ubiquitin. Thus, RTA avoids the usual fate of dislocated proteins (destruction that is mediated by targeting ubiquitinylated proteins to the cytosolic proteasomes). In the mammalian cell cytosol, RTA then undergoes triage by the cytosolic molecular chaperones Hsc70 and Hsp90 and their co-chaperones, as well as by one subunit (RPT5) of the proteasome itself, that results in its folding to a catalytic conformation, which de-purinates ribosomes, thus halting protein synthesis.
Although Agr2 mRNA levels are correlated with the tamoxifen therapy response, AGR2 protein levels have yet to be statistically associated with the therapy. A combinatorial therapy using the anastrozole and fulvestrant has been shown to prevent binding of the ER to the Agr2 promoter, and there has been improved prognosis in the patients receiving it, possibly because AGR2 expression in the tumors have been reduced. What AGR2 does in cancers is poorly understood. In breast cancer, HSP90 is a molecular chaperone expressed in tumor cells when there exists an excess of unfolded protein, and its co-chaperone has been reported to induce expression of AGR2, so AGR2 may be used by the endoplasmic reticulum to assist with protein folding to alleviate proteotoxic stress.
A Ginetta G50 Supercup car. Porsche Carrera Cup GB Race at Donington Park The TOCA Support Package consists of five main support championships, which support the championship at almost every round, along with several smaller championships supporting one or two events. All the support championships are either Single Make Championships or Formula racing. After previously supported the BTCC in the late 1990s and then in 2013 and 2014, the British Formula Ford Championship announced that it was folding to become the MSA Formula, the FIA's Formula 4 championship in the UK for the 2015 season. Known as F4 British Championship from 2016, the championship uses Mygale carbon-fibre monocoque chassis and a Ford 1.6L EcoBoost engine as used in the more modern Formula Ford cars.
The third chapter discusses the confluence of Arabic and European mathematics, into the 18th century, with topics including the symmetries of folded objects and the attempted use of folding to prove the parallel postulate. Although Eugenio Beltrami continued to use folded models to investigate non-Euclidean geometry into the 19th century, the fourth chapter of the book argues that other 19th-century uses of folding were more pedagogical, including the use of folded models to demonstrate mathematical concepts, their applications in chemistry, and the introduction of folding into kindergarten programs by Friedrich Fröbel. The late 19th century also saw the publication in India and then the west of the book Geometric Exercises in Paper Folding, by T. Sundara Row. The final two chapters concern the 20th century and current topics of research in this area.
The Grateful Dead was an American rock band formed in 1965 in Palo Alto, California. The band is known for its eclectic style, which fused elements of rock, folk, country, jazz, bluegrass, blues, gospel, and psychedelic rock;"purveyors of freely improvised space music" – Blender Magazine, May 2003 "’Dark Star’, both in its title and in its structure (designed to incorporate improvisational exploration), is the perfect example of the kind of ’space music’ that the Dead are famous for. Oswald's titular pun ’Grayfolded’ adds the concept of folding to the idea of space, and rightly so when considering the way he uses sampling to fold the Dead's musical evolution in on itself." – Islands of Order, Part 2, by Randolph Jordan, in Offscreen Journal , edited by Donato Totaro, Ph.D, film studies lecturer at Concordia University since 1990.
For example, the spatial arrangement of conserved residues may suggest whether a particular residue is conserved to stabilize the folding, to participate in binding some small molecule, or to foster association with another protein or nucleic acid. Homology modeling can produce high-quality structural models when the target and template are closely related, which has inspired the formation of a structural genomics consortium dedicated to the production of representative experimental structures for all classes of protein folds. The chief inaccuracies in homology modeling, which worsen with lower sequence identity, derive from errors in the initial sequence alignment and from improper template selection. Like other methods of structure prediction, current practice in homology modeling is assessed in a biennial large-scale experiment known as the Critical Assessment of Techniques for Protein Structure Prediction, or CASP.
With the importance of proteins established, the heat shock response can be employed under stress to induce heat shock proteins (HSP), also known as molecular chaperones, that help prevent or reverse protein misfolding and provide an environment for proper folding. Protein folding is already challenging due to the crowded intracellular space where aberrant interactions can arise; it becomes more difficult when environmental stressors can denature proteins and cause even more non-native folding to occur. If the work by molecular chaperones is not enough to prevent incorrect folding, the protein may be degraded by the proteasome or autophagy to remove any potentially toxic aggregates. Misfolded proteins, if left unchecked, can lead to aggregation that prevents the protein from moving into its proper conformation and eventually leads to plaque formation, which may be seen in various diseases.
Nag Hammadi bindings were constructed with a textblock of papyrus sheets, assembled into a single section and trimmed along the fore edge after folding to prevent the inner sheets from extending outward beyond the outer sheets. Because the inner sheets were narrower than the outer sheets after trimming, the width of text varied through the textblock, and it is likely that the papyrus was not written on until after it was bound; this, in turn, would have made it a necessity to calculate the number of sheets needed for a manuscript before it was written and bound.Szirmai, 12-13.Turner points out that a scribe could, however, insert a single leaf either in the middle of the book or at the end; some evidence points to this having been done in two of the Nag Hammadi codices.
The practice is followed by hotels all over the world, according to Stephen Gill, a British photographer who published a book of pictures of folded hotel toilet paper from various nations.Barnett, Laura, "The loo roll that says I love you: Stephen Gill explains why he spent three years taking pictures of hotel toilet paper", The Guardian, September 26, 2007, retrieved March 31, 2009 Dr. Susan Blackmore, who uses the example of hotel toilet paper folding to illustrate the use of memes, pointed out in the 2006 Darwin Day Lecture before the British Humanist Association that even a remote guesthouse she visited in rural Assam in India folded the first sheet on its rolls of toilet paper. Hotel toilet paper folding is such an institution that in the horror movie 1408 it is used as one of the eerie happenings noticed by the main character—after using the toilet paper, he finds it mysteriously has been freshly folded over.Salles, Steve, movie critic, "Roaches, bedbugs the least of your worries in '1408'", movie review, Standard-Examiner, Ogden, Utah, June 22, 2007, retrieved via NewsBank.
In an effort to be included in the ABA–NBA merger, the Spirits' owners, the Silna brothers, proposed selling the Spirits to a Utah group, buying the Kentucky Colonels franchise, and moving the Colonels to Buffalo to replace the Buffalo Braves, who were then planning to move to the Miami region (The Buffalo franchise would eventually move to Southern California, first as the San Diego Clippers before moving north to Los Angeles; Salt Lake City and Miami eventually gained NBA franchises, Salt Lake City through the move of New Orleans a few years later in 1979, and Miami via expansion in 1988). The Spirits were not included in the merger, but the Silna brothers nonetheless managed to turn the merger, for them, into one of the greatest deals in the history of professional sports:Pluto, Terry, Loose Balls: The Short, Wild Life of the American Basketball Association (Simon & Schuster, 1990), , pp.431–433Darren Rovell, NBA Edition: Silna Family "Fortune" And The Draft, CNBC, June 28, 2007 In June 1976, the remaining ABA owners agreed, in return for the Spirits folding, to pay the St. Louis owners $2.2 million in cash up front in addition to a 1/7 share of the four remaining teams' television revenues in perpetuity.
After years of glory the club was becoming conservative, although they would not admit it themselves. Other clubs were increasingly turning to professionalism, while players from FFK still played football in addition to having normal jobs. Training regimes were becoming more rigorous than before, but in Fredrikstad they felt that training more than twice a week would ruin the joy of playing football. There is also the sentiment that, in light of the club's formidable history, newer generations of FFK-players were given too much responsibility, folding to the pressure again and again whenever things were starting to look brighter. Fredrikstad was to struggle throughout the 1970s. They reached the cup final in 1971, but lost to Rosenborg, who were by now firmly en route to becoming a giant in Norwegian football. In 1972, they were runners-up in the league to Viking FK only on goal difference, as both teams finished the season on 34 points. In 1973, for the first time in the club's history, FFK were relegated. They immediately gained promotion via the playoffs and by 1975 were back in the highest division, where they stayed for two seasons before facing relegation yet again. The elevator ride between divisions continued until 1984.

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