Aurally, "experiment" and "empire" come dangerously close, and the poet seems to identify himself almost embryonically, as if that non-English mother still envelops him and influences his poetic/genetic code.
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Erasure of the lactosylceramide synthase by quality focusing on is embryonically deadly.
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The neurons in the inferior ganglion of the vagus nerve are embryonically derived from epibranchial neurogenic placodes.
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Expression of tailless is activated by torso protein in the poles of the embryo. Tailless is also regulated in a complex manner by the maternal-effect gene bicoid. Both embryonically-transcribed hunchback and maternally-transcribed hunchback are activated by bicoid protein in the anterior and is inhibited in the posterior by nanos protein. Embryonically-transcribed hunchback protein is able to exhibit the same effects on Krüppel and knirps as maternally-transcribed hunchback.
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Embryonic development of the nervous system. The neural crest can be seen in light green. The neurons in the superior ganglion of the vagus nerve are embryonically derived from the neural crest.
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The development of the CAM is similar to that of the allantois in mammals. Its growth starts from day 3 of embryonic development. Development of the allantois occurs extra embryonically from the ventral wall of the endodermal hindgut. Partial fusion of the chorion and allantois occurs between days 5 and 6.
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Most of the development of the OL occurs at the end of the larval stage. Prospero plays a different role in post embryonic neurogenesis than it did in the embryonic phase. Prospero is post-embryonically upregulated in order to promote neurons to exit the cell cycle, after GMCs differentiate during the embryogenesis Prospero is nearly undetectable.
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Development of the nervous system. The glomus type I cells of the carotid body are derived from the neural crest and can be seen in green. Glomus type I cells are embryonically derived from the neural crest. In the carotid body the respiratory chemoreceptors need a period of time postnatally in order to reach functional maturity.
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VE-PTP is a member of the classical protein tyrosine phosphatase (PTP) family. The deletion of the gene in mouse models was shown to be embryonically lethal, thus indicating that it is important for vasculogenesis and blood vessel development. In addition, it was shown to participate in adherens junctions complex and regulate vascular permeability. Recently, Soni et al.
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Herman F.C. ten Kate, the younger (7 February 1858 – 3 February 1931) was a Dutch anthropologist. Ten Kate's anthropological knowledge gathered over several decades of travel was considered as "embryonically modern" attesting to his scientific stature. He held the view that the science of anthropology of non-Western cultures provided insight into deficiencies in Western culture. A linguist, ten Kate was fluent in eight languages.
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RIG-I orthologs are found in mammals, geese, ducks, some fish, and some reptiles. RIG-I is in most cells, including various innate immune system cells, and is usually in an inactive state. Knockout mice that have been designed to have a deleted or non-functioning RIG-I gene are not healthy and typically die embryonically. If they survive, the mice have serious developmental dysfunction.
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The labrum is a flat extension of the head (below the clypeus), covering the mandibles. Unlike other mouthparts, the labrum is a single, fused plate (though it originally was—and embryonically is—two structures). It is the upper-most of the mouthparts and located on the midline. It serves to hold food in place during chewing by the mandibles and thus can simply be described as an upper lip.
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FGFR3 inhibitors are in early clinical trials as a cancer treatment, eg. BGJ398 for urothelial carcinoma. The FGFR3 receptor has a tyrosine kinase signaling pathway that is associated with many biological developments embryonically and in tissues. Studying the tyrosine kinase signaling pathway that FGFR3 displays has played a crucial role in the development of research of several cell activities such as cell proliferation and cellular resistance to anti-cancer medications.
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BMAL1 KO is not embryonically lethal and mice with BMAL1 ablated in adulthood do not express the symptoms of BMAL1 KO mice. BMAL1 binding is regulated in a tissue-specific manner by numerous factors including non-circadian ones. Following, tissue- specific KOs cause unique effects. BMAL1 has been shown to be important in bone metabolism as osteoblast BMAL1 KO mice have lower bone mass than their wild type counterparts.
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Cotyledons are formed during embryogenesis, along with the root and shoot meristems, and are therefore present in the seed prior to germination. True leaves, however, are formed post-embryonically (i.e. after germination) from the shoot apical meristem, which is responsible for generating subsequent aerial portions of the plant. The cotyledon of grasses and many other monocotyledons is a highly modified leaf composed of a scutellum and a coleoptile.
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The neocortex is derived embryonically from the dorsal telencephalon, which is the rostral part of the forebrain. The neocortex is divided, into regions demarcated by the cranial sutures in the skull above, into frontal, parietal, occipital, and temporal lobes, which perform different functions. For example, the occipital lobe contains the primary visual cortex, and the temporal lobe contains the primary auditory cortex. Further subdivisions or areas of neocortex are responsible for more specific cognitive processes.
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The patterning from the maternal genes work to influence the expression of the segmentation genes. The segmentation genes are embryonically expressed genes that specify the numbers, size and polarity of the segments. The gap genes are directly influenced by the maternal genes and are expressed in local and overlapping regions along the anterior/posterior axis. These genes are influenced by not only the maternal genes, but also by epistatic interactions between the other gap genes.
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OPC transplants contribute to remyelination, but it is difficult to maintain such cells in adequate concentrations at high purity. Finding a source for these cells remains impractical as of 2016. Should adult cells be used for transplantation, a brain biopsy would be required for each patient, adding to the risk of immune rejection. Embryonically derived stem cells have been demonstrated to carry out remyelination under laboratory conditions, but some religious groups are opposed to their use.
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Nor did his devotion to the justification and > glorification of Florence permit him to see in the altered fortunes of his > city a repetition of the pattern of decline he had illustrated in the > histories of the great dynasties of his age.Green (1967), 168. Louis Green asserts that Giovanni's Cronica expressed the outlook of the merchant community in Florence at the time, but also provided valuable indications of "how that outlook was modified in a direction away from characteristically medieval to embryonically modern attitudes."Green (1967), 161.
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Netrins share the same terminal structure with vertebrate laminins but appear minimally related. The basement membrane assembly across species, Vertebrate laminin-1 (α1β1γ1) and laminin-10 (α5β1γ1), like the two Caenorhabditis elegans laminins, are embryonically expressed and are essential for basement membrane assembly. During the basement assembly process laminins anchor to the cell surface through their G domains after polymerizing through their LN domains. Netrins are involved in heterotropic LN domain interactions during this process which suggests that although similar in structure, the functions of the two families are different.
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Netrins share the same terminal structure with vertebrate laminins but appear minimally related. The basement membrane assembly across species, Vertebrate laminin-1 (α1β1γ1) and laminin-10 (α5β1γ1), like the two Caenorhabditis elegans laminins, are embryonically expressed and are essential for basement membrane assembly. During the basement assembly process laminins anchor to the cell surface through their G domains after polymerizing through their LN domains. Netrins are involved in heterotropic LN domain interactions during this process which suggests that although similar in structure, the functions of the two families are different.
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Locke's Second Treatise also points towards the heart of the anti-mercantilist critique: that the wealth of the world is not fixed, but is created by human labor (represented embryonically by Locke's labor theory of value). Mercantilists failed to understand the notions of absolute advantage and comparative advantage (although this idea was only fully fleshed out in 1817 by David Ricardo) and the benefits of trade., ch. 8. For instance, imagine that Portugal was a more efficient producer of wine than England, yet in England, cloth could be produced more efficiently than it could in Portugal.
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1962; 4th ed. 1970) The defining characteristic of a vertebrate is the vertebral column, in which the notochord (a stiff rod of uniform composition) found in all chordates has been replaced by a segmented series of stiffer elements (vertebrae) separated by mobile joints (intervertebral discs, derived embryonically and evolutionarily from the notochord). However, a few fish have secondarily lost this anatomy, retaining the notochord into adulthood, such as the sturgeon. The vertebral column consists of a centrum (the central body or spine of the vertebra), vertebral arches which protrude from the top and bottom of the centrum, and various processes which project from the centrum or arches.
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The female lays eggs which hatch as much-shortened versions of the adults, with only a few segments and as few as three pairs of legs. With the exception of the two centipede orders Scolopendromorpha and Geophilomorpha, which have epimorphic development (all body segments are formed segments embryonically), the young add additional segments and limbs as they repeatedly moult to reach the adult form. The process of adding new segments during postembryonic growth is known as anamorphosis, of which there are three types; euanamorphosis, where every moult is followed by addition of new segments, even after reaching sexual maturity. Emianamorphosis, where new segments are added until a certain stadium, and further moults happens without addition of segments.
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The defining characteristic of a vertebrate is the vertebral column, in which the notochord (a stiff rod of uniform composition) found in all chordates has been replaced by a segmented series of stiffer elements (vertebrae) separated by mobile joints (intervertebral discs, derived embryonically and evolutionarily from the notochord). However, a few vertebrates have secondarily lost this anatomy, retaining the notochord into adulthood, such as the sturgeon and coelacanth. Jawed vertebrates are typified by paired appendages (fins or legs, which may be secondarily lost), but this trait is not required in order for an animal to be a vertebrate. Fossilized skeleton of Diplodocus carnegii, showing an extreme example of the backbone that characterizes the vertebrates.
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This phenomenon is most consistently found in the Inland North, the Upper Midwest, New England, New York City, and the mid-Atlantic areas of Pennsylvania (including Philadelphia), Maryland, and Delaware, as well as in Virginia. It is somewhat less common in the lower Midwest, the West, and the South. However, there is considerable variation in the raising of , and it can be found inconsistently throughout the United States. The raising of is also present in Ulster English, spoken in the northern region of the island of Ireland, in which is split between the sound (before voiced consonants or in final position) and the sound (before voiceless consonants but also sometimes in any position); phonologist Raymond Hickey has described this Ulster raising as "embryonically the situation" for Canadian raising.
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The murine Fat1 knockout mouse is not embryonically lethal but pups die within 48-hours due to the abnormal fusion of foot processes of the podocytes within the kidney. These Fat1 knockout mice also showed partially penetrant but often severe midline defects including holoprosencephaly, microphthalmia-anophthalmia and in rare cases cyclopia. It has been shown that the EVH motifs in the cytoplasmic tail of mouse Fat1 interact with Ena/VASP and ablation of Fat1 by RNAi leads to decreased cell migration of rat epithelial cells The cytoplasmic tail of Fat1 has also been shown to bind the transcriptional repressor Atrophin in rat vascular smooth muscle cells At the carboxyl terminus of FAT1 lies a PDZ domain (PSD95/Dlg1/ZO-1) ligand motif (-HTEV). Zebrafish Fat1 was found to bind the protein scribble and regulate Hippo signalling Using the human SHSY5Y cell line as a model of neuronal differentiation, human FAT1 was shown to regulate Hippo kinase components with loss of FAT1 leading to nucleocytoplasmic relocation of TAZ and enhanced transcription of the Hippo target gene CTGF.
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