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3 Sentences With "desynchronizes"

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Clock drift refers to several related phenomena where a clock does not run at exactly the same rate as a reference clock. That is, after some time the clock "drifts apart" or gradually desynchronizes from the other clock. All clocks are subject to drift, causing eventual divergence unless resynchronized. In particular, the drift of crystal-based clocks used in computers requires some synchronization mechanism for any high-speed communication.
On the neurological level, PFA is hypothesized to involve desynchronization of the part of an object-encoding neuronal ensemble (objectNE) from the rest of the ensemble. For example, when one imagines a kettle with a broken handle, the lateral prefrontal cortex (LPFC) desynchronizes the handle from the rest of the objectNE of the kettle. LPFC- driven shift of a part of the objectNE out-of-phase with the rest of the ensemble, results in the perception of a new object encoded by those neurons that remain firing synchronously. PFA was coined in to define the component of active imagination acquired by the first stone tools makers Homo habilis and Homo erectus.
Tetrodotoxin, which blocks action potentials, not only desynchronizes the cell population, but also suppresses the level of clock gene expression, demonstrating that neuronal networks play a dominant role in oscillation of rhythms in the SCN. Using the same Per-luc mice with the optical fiber inserted to the brain, Okamura's team succeeded in monitoring the rhythmic gene expression of the clock gene in real-time in freely moving mice, demonstrating that the Per gene is activated in the daytime and rests in the nighttime in the SCN. Okamura discovered that flashing NMDA, which is analogous to light stimuli, instantly altered the phase of the core clock oscillation of a slice of SCN. This proved that there is rhythmic transcription of genes at the single cell level.

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