Hypersensitivity to the benzimidazole class of compounds contraindicates its use.
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A CT scan is essential in evaluating for a hemorrhagic event, which contraindicates thrombolytic therapy.
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Heparin-induced thrombocytopenia is an immune-mediated complication of heparin administration that contraindicates further heparin exposure.
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Additional muscle deficits can contraindicate tendon transfer, namely the serratus anterior muscle or the muscles-to-be-transferred themselves. Serratus anterior muscle deficit is another cause of scapular winging and decreases the efficacy of an Eden-Lange procedure, but it can be overcome with a simultaneous pectoralis major transfer. Muscular dystrophy often contraindicates tendon transfer, because the muscles transferred are either dystrophic or capable of becoming dystrophic. A pertinent example is facioscapulohumeral muscular dystrophy (FSHD), which commonly affects the trapezius, causing a need for scapular stabilization, but also commonly affects other periscapular muscles, which contraindicates the transfer.
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Therefore, the nursing mouth care policy for the Health Care Corporation of St. Johns recommended discontinuing use of lemon glycerine swabs for oral care due to its adverse effects. The evidence contraindicates the use of lemon glycerine swabstick for individuals suffering from dry mouth.
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This contraindicates certain drug control strategies. And, evidence from illicit distribution/trafficking networks suggest that gang membership isn't important to the flow of resources between violent, competing groups. With community outcomes in mind, this would contraindicate bans on gang membership. The use of evidence in this manner sometimes leads to law enforcement decisions that contrast with popular intuition.
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Eplerenone is contraindicated in patients with hyperkalaemia, severe renal impairment (creatinine Cl less than 30 ml/min), or severe hepatic impairment (Child-Pugh score C). The manufacturer of eplerenone also contraindicates ( relative C.I. ) concomitant treatment with ketoconazole, itraconazole or other potassium-sparing diuretics (though the manufacturer still considers taking these drugs to be absolute C.I.) Potential benefits should be weighted against possible risks.
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Immediate loading implants may have a higher rate of failure, potentially due to being loaded immediately after trauma or extraction, but the difference with proper care and maintenance is well within statistical variance for this type of procedure. More often, osseointegration failure occurs when a patient is either too unhealthy to receive the implant or engages in behavior that contraindicates proper dental hygiene including smoking or drug use.
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In France, the country's health agency contraindicates the use of NSAIDs, including aspirin, after the sixth month of pregnancy. In October 2020, the U.S. Food and Drug Administration (FDA) required the drug label to be updated for all nonsteroidal anti-inflammatory medications to describe the risk of kidney problems in unborn babies that result in low amniotic fluid. They are recommending avoiding NSAIDs in pregnant women at 20 weeks or later in pregnancy.
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Amphetamine is classified in US pregnancy category C. This means that detriments to the fetus have been observed in animal studies and adequate human studies have not been conducted; amphetamine may still be prescribed to pregnant women if the potential benefits outweigh the risks. Amphetamine has also been shown to pass into breast milk, so the USFDA advises mothers to avoid breastfeeding when using it. Due to the potential for stunted growth, the USFDA advises monitoring the height and weight of children and adolescents prescribed amphetamines. Prescribing information approved by the Australian Therapeutic Goods Administration further contraindicates anorexia.
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