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"variegate" Definitions
  1. to diversify in external appearance especially with different colors : DAPPLE
  2. to enliven or give interest to by means of variety

34 Sentences With "variegate"

How to use variegate in a sentence? Find typical usage patterns (collocations)/phrases/context for "variegate" and check conjugation/comparative form for "variegate". Mastering all the usages of "variegate" from sentence examples published by news publications.

The variegate objects in the room, the suspended nude torso, the neon palm leaf light all give a sense of treasured goods and uncovered objects brought at a sleepover.
Variegate porphyria has an autosomal dominant pattern of inheritance. Mutations in the PPOX gene cause variegate porphyria. The PPOX gene makes a membrane bound mitochondrial enzyme called protoporphyrinogen oxidase, which is critical to the chemical process that leads to heme production. The activity of this enzyme is reduced by 50 percent in most people with variegate porphyria.
An additional aggravating mutation affecting variegate porphyria can be found at 6p21.3 on the HFE gene. A 2006 clinical, biochemical and mutational study of eight Swiss variegate porphyria patients and their families found four novel PPOX gene mutations believed to be unique to the Swiss population.
Some known Burseraceae fruit consumers include hornbills (Buceros bicornis, Ceratogyma atrata, C. cylindricus, Penelopides panini), oilbirds (Steatnoris caripensis), fruit pigeons, warblers, vireos, orioles, flycatchers, tanagers, woodpeckers, loeries, primates (Cercopithecus spp., Lophocebus albigena), lemurs (Varecia variegate subsp. variegate), and sun bears (Helarctos malayanus). The fruits may also have been water dispersed.
Some people with variegate porphyria have skin that is overly sensitive to sunlight (photosensitive). Areas of skin exposed to the sun develop severe blistering, scarring, changes in pigmentation, and increased hair growth. Exposed skin becomes fragile and is easily damaged. Rarely, the signs and symptoms of variegate porphyria can begin in infancy or early childhood.
A new stabilized variegated variety of H. vulgare, billed as H. vulgare variegate, has been introduced for cultivation as an ornamental and pot plant for pet cats to nibble.
Other common names for this ray include Bleeker's variegate ray and ocellate whipray. The reticulate whipray (H. uarnak) and the leopard whipray (H. leoparda) are closely related to the honeycomb whipray.
In South Africa, the prevalence of variegate porphyria is approximately 1 in 300. In Finland, the prevalence is approximately 1 in 75,000. It is also found in Argentina, Sweden, and Australia.
1979 C. Roubet. Économie Pastorale Préagricole en Algérie Orientale: le Néolithique de Tradition Capsienne. Paris: CNRS. Anatomically, Capsian populations were modern Homo sapiens, traditionally classed into two variegate types: Proto-Mediterranean and Mechta-Afalou on the basis of cranial morphology.
When diagnosing Congenital Erythroipoetic Porphyria (Gunther Disease) one must exclude other forms of porphyria. These include Hepatoerythropoietic Porphyria and rare homozygous variants of Variegate Porphyria, Hereditary Coproporphyria, and STING-associated vasculopathy with onset in Infancy (SAVI). Mild variants may be present similarly to Porphyria Cutanea Tarda. There are 4 steps in establishing the diagnosis of any porphyria.
Prickly heat, which is caused by warm weather or heat is not the same as PLE. Photosensitivity is also found in some of the porphyrias. Nearly all cases of porphyria cutanea tarda exhibit blister formation on the skin within 2–4 days of light exposure. Variegate porphyria and hereditary coproporphyria can also exhibit symptoms of light-induced blisters.
Variegate porphyria (also porphyria variegata or mixed porphyria), which results from a partial deficiency in PROTO oxidase, manifests itself with skin lesions similar to those of porphyria cutanea tarda combined with acute neurologic attacks. Hereditary coproporphyria, which is characterized by a deficiency in coproporphyrinogen oxidase, coded for by the CPOX gene, may also present with both acute neurologic attacks and cutaneous lesions. All other porphyrias are either skin- or nerve-predominant.
Mechanisms other than allergen-antibody interactions are known to cause histamine release from mast cells. Many drugs, for example morphine, can induce direct histamine release not involving any immunoglobulin molecule. Also, a diverse group of signaling substances called neuropeptides, have been found to be involved in emotionally induced hives. Dominantly inherited cutaneous and neurocutaneous porphyrias (porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria and erythropoietic protoporphyria) have been associated with solar urticaria.
Variegate porphyria, also known by several other names, is an autosomal dominant porphyria that can have acute (severe but usually not long-lasting) symptoms along with symptoms that affect the skin. The disorder results from low levels of the enzyme responsible for the seventh step in heme production. Heme is a vital molecule for all of the body's organs. It is a component of hemoglobin, the molecule that carries oxygen in the blood.
One of the many hypothesized diagnoses of the artist Vincent van Gogh is that he and his siblings, in particular his brother Theo, suffered from AIP and syphilis. Another theorized sufferer was King George III of the United Kingdom who even had a medallion struck to commemorate his "curing". His descendant Prince William of Gloucester was reliably diagnosed with variegate porphyria in 1968. It is probable that the philosopher Jean- Jacques Rousseau suffered from porphyria.
After learning that Landon was put into the camp for a relatively minor offense, further research reveals that Driscoll is Landon's father. It appears they have a genetic disease, and House eventually concludes it's variegate porphyria. Meanwhile, House tries to help Cuddy's daughter Rachel get into a prestigious preschool. He first visits the school under false pretenses, takes pictures of all the toys in the test room and buys several of them.
As the author casts these subjects into his lines,he uses a sharp and complex style. His stanzas variegate in length and his poetry disturbs and re-forms the routine language. The word combinations strikingly violate the order with outstanding, unexpected images. His free-verse often depends on the cadence or grouping of phrases, and the reading depends on either a slowing down or a speeding up till it reaches an emphasis in the final lines.
The initial diagnosis of acute porphyria is confirmed by urinalysis, including the common method, the Watson-Schwartz test. Elevated urine porphobilinogen confirms diagnosis of AIP, hereditary coproporphyria (HCP), or variegate porphyria (VP). A positive test should be indicated with an increase of five times normal, not just a slight increase which can occur with dehydration. To distinguish between AIP from HCP and VP, fecal porphyrin levels are normal in AIP but elevated in HCP and VP. Rapid, accurate diagnosis is important.
Similarly, poikilohydry occurs in land plants which survive environmental conditions when water supplies are seasonal or intermittent, as in the liverwort genus Targionia, which lives in Mediterranean habitats with hot dry summers. The term is derived from Ancient Greek ποικίλος (poikílos, “spotted or variegate”). The antonym of poikilohydry is homoiohydry, a suite of morphological adaptations and strategies that enable plants to regulate or achieve homeostasis of cell and tissue water content. The vascular plants have largely lost the capacity to tolerate dehydration.
The variegate Lithuanian mythology of this time (legend about emigration of Palemon from Rome to Lithuania, legend about the founding of the capital of Lithuania Vilnius by Duke Gediminas, and other pieces) had been presented in a spirit of high lucid and virtuous patriotism. Original architectural style (with Western-European and Byzantine tendencies fused in it) and other manifestations of material culture of this time prove Lithuania as a distinctive cultural unit. However, Lithuania was too little known to Western Europeans in these times.
Etheostoma variatum (common name variegate darter) is a species of darter. It is native to the eastern United States where it occurs primarily in the Ohio River basin; it is present in the states of Ohio, New York, Pennsylvania, Indiana, West Virginia and Kentucky with a small population in Virginia. It is a large darter, growing to long, orange-red with black vertical barring on its body, and horizontal barring on its front dorsal fin. Its typical habitat is swift-flowing riffles with rubble, boulder and gravel.
Bracken Nature Reserve is a piece of protected land in Brackenfell in the Western Cape, South Africa. This park preserves badly threatened Cape Flats Sand Fynbos and Swartland Granite Renosterveld vegetation. A diverse array of orchids, succulents and flowering bulbs are among the over 160 plant species that occur here. Of these, ten occur only within the City of Cape Town and are in serious danger of extinction, including Antimima aristulata, cowslip (Lachenalia aloides), canary yellow vygie (Lampranthus glaucus) and carrion flower (Orbea variegate).
Clinically, patients affected with HCP present similarly to those with other acute porphyrias, such as acute intermittent porphyria (AIP) and variegate porphyria (VP). Patients with HCP and VP can present with symptoms shared between the acute and cutaneous porphyrias. This includes the acute attacks of abdominal pain, nausea, vomiting, diarrhea, tachycardia, hypertension and seizures, as well as the cutaneous findings seen in porphyria cutanea tarda (PCT), namely increased skin fragility, bullous lesions after exposure to sunlight and increased scarring. Individuals with HCP may be asymptomatic in the absence of triggering factors.
As well as parasitizing the nymphs the wasps can also cause high level of mortality among them when they are probed by or fed on by the adults, 76% of the first instar nymphs which were probed or fed on by adult balios wasps subsequently died. A parasitized nymph has a tiny pinhole on its right side in the middle and turns dark yellow and as it grows the asp larva can be visible. When the adult wasp emerges it creates a neat round hole in the nymph's exoskeleton. Encarsia variegate has been recorded as a hyperparasitoid of B. balios.
Acute and chronic hepatic porphyrias (acute intermittent porphyria, porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria) and tyrosinemia type I are risk factors for hepatocellular carcinoma. The diagnosis of an acute hepatic porphyria (AIP, HCP, VP) should be sought in patients with HCC without typical risk factors of hepatitis B or C, alcoholic liver cirrhosis, or hemochromatosis. Both active and latent genetic carriers of acute hepatic porphyrias are at risk for this cancer, although latent genetic carriers have developed the cancer at a later age than those with classic symptoms. Patients with acute hepatic porphyrias should be monitored for HCC.
In severe cases that begin early in life, the enzyme is almost completely inactive. Nongenetic factors such as certain drugs, stress, and others listed above can increase the demand for heme and the enzymes required to make heme. The combination of this increased demand and reduced activity of protoporphyrinogen oxidase disrupts heme production and allows byproducts of the process to accumulate in the liver, triggering an acute attack. Variegate porphyria is inherited in an autosomal dominant pattern, which means the defective gene is located on an autosome, and inheriting one copy of the defective gene from an affected parent is sufficient to cause the disorder.
Both Kauffman (1918) and Graham (1944) described C. ebulbosus and C. quadrifidus; Graham, however, only included C. quadrifidus in his key to his descriptions of Coprinus species. In 1979, W. Patrick published a comparative analysis of the three taxa from material collected by Peck, and, after concluding that the three were not sufficiently distinct to be considered separate species, reduced them to synonymy with Coprinopsis variegata, the earliest name. The specific epithet variegata derives from the Latin passive verb participle variegatus meaning "to have different colors, to variegate". The synonym name quadrifidus refers to the four segments into which the cap frequently split when mature, while ebulbosus means "not being bulbous".
The acute porphyrias are acute intermittent porphyria (AIP), variegate porphyria (VP), aminolevulinic acid dehydratase deficiency porphyria (ALAD) and hereditary coproporphyria (HCP). These diseases primarily affect the nervous system, resulting in episodic crises known as acute attacks. The major symptom of an acute attack is abdominal pain, often accompanied by vomiting, hypertension (elevated blood pressure), and tachycardia (an abnormally rapid heart rate). The most severe episodes may involve neurological complications: typically motor neuropathy (severe dysfunction of the peripheral nerves that innervate muscle), which leads to muscle weakness and potentially to quadriplegia (paralysis of all four limbs) and central nervous system symptoms such as seizures and coma.
Repeat testing during an attack and subsequent attacks may be necessary in order to detect a porphyria, as levels may be normal or near-normal between attacks. The urine screening test has been known to fail in the initial stages of a severe, life-threatening attack of acute intermittent porphyria. Up to 90% of the genetic carriers of the more common, dominantly inherited acute hepatic porphyrias (acute intermittent porphyria, hereditary coproporphyria, variegate porphyria) have been noted in DNA tests to be latent for classic symptoms and may require DNA or enzyme testing. The exception to this may be latent post-puberty genetic carriers of hereditary coproporphyria.
In 2002, a DNA investigation into the hypothesis of a variegate porphyria mutation was introduced into the Aboriginal population by shipwrecked sailors was undertaken at the Queen Elizabeth II Medical Centre in Nedlands, Western Australia and the Stellenbosch University in South Africa. The research concluded the mutations were not inherited from shipwrecked sailors. The presence of similar European genetic maladies in the Aboriginal population (such as Ellis–van Creveld syndrome) as from VOC shipwreck survivors is also doubtful. Dutch-Indigenous links, via the VOC wrecks are less plausible because of the importation of hundreds of divers for use in the Western Australian pearling industry in the mid-to-late 19th century.
Among the songs were four tracks issued on singles by the Rolling Stones in the first half of 1966, the A-sides of which were "19th Nervous Breakdown" and "Paint It, Black". Referring to the atmosphere at RCA, Richards told Beat Instrumental magazine in February 1966: "Our previous sessions have always been rush jobs. This time we were able to relax a little, take our time." The main engineer for the album, Dave Hassinger, was pivotal in making the group feel comfortable during the sessions, as he let them experiment with instrumentals and team up with session musicians like Jack Nitzsche to variegate their sound.
In 1988, an American woman who had married into the Mallard family contacted Dr Playford and described how her husband had died some years before from a disease called variegate porphyria. Playford found that the disease was genetically linked and initially confined to Afrikaners and that all cases of the disease in South Africa were traceable to Gerrit Jansz and Ariaantjie Jacobs, who had married in The Cape in 1688. Zuytdorp arrived at the Cape in March 1712 where it took on more than 100 new crew. One of the Jansz' sons could have boarded the ship at this time and thus become the carrier of the disease into the Australian Aboriginal population.
The adult is yellowish with pale transverse lines and black spots on the forewing. Larva are hairy and reddish brown. Head reddish with white hairs. The caterpillar is major pest on several agricultural crops such as Ziziphus mauritiana, Ziziphus xylopyra, Ziziphus jujuba, Terminalia cattappa, Ricinus communis, Pyrus communis, Quisqualis indica, Sesamum indicum, Shorea robusta, Solanum melongena, Tectona grandis, Rosa, Rubus, Toxicodendron succedaneum, Trewia nudiflora, Tylophora asthmatica, Vigna unguiculata, Punica granatum, Codiaeum, Coffea, Dalbergia sissoo, Desmodium oojeinense, Gossypium, Grewia asiatica, Helianthus annuus, Hibiscus rosa- sinensis, Limonia elephantum, Malus pumila, Mangifera indica, Manihot esculenta, Manilkara zapota, Musa, Pelargonium, Persea bombycina, Plantago, Prunus persica, Psidium, Punica granatum, Abelmoschus esculentus, Aleurites fordii, Aleurites montana, Artocarpus heterophyllus, Bauhinia variegate, Bombax, Cajanus cajan, Camellia sinensis, Cinnamomum and Citrus.
The organs mainly involved in heme synthesis are the liver (in which the rate of synthesis is highly variable, depending on the systemic heme pool) and the bone marrow (in which rate of synthesis of Heme is relatively constant and depends on the production of globin chain), although every cell requires heme to function properly. However, due to its toxic properties, proteins such as Hemopexin (Hx) are required to help maintain physiological stores of iron in order for them to be used in synthesis. Heme is seen as an intermediate molecule in catabolism of hemoglobin in the process of bilirubin metabolism. Defects in various enzymes in synthesis of heme can lead to group of disorder called porphyrias, these include acute intermittent porphyria, congenital erythropoetic porphyria, porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, erythropoietic protoporphyria.

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