Wood is 79 years old, an age at which enfeeblement is hardly rare.
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The enfeeblement of the parliamentary opposition is already generating talk about extra-parliamentary resistance.
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The old rulers are ridiculed for corruption, economic mismanagement and the military enfeeblement they are said to have overseen.
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The findings suggest, in effect, that skipping workouts now need not guarantee enfeeblement later, and if we forget what fitness once felt like, our muscles recollect.
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My current guesses for the most likely failure modes are twofold: The gradual enfeeblement of human society as more knowledge and know-how resides in and is transmitted through machines and fewer humans are motivated to learn the hard stuff in the absence of real need.
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Map of Caucasus Region 1405. After the devastating invasions by Timur and subsequent enfeeblement of the Kingdom of Georgia, it soon faced a new threat. Timur's death in 1405 marked the beginning of the end of his Empire, unified only by fear and blood of the subjected peoples. Turkomans, particularly the Kara Koyunlu clan, were among the first to rebel against Shah Rukh who ruled most of the Persia and Mawerannahr.
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After the devastating invasions by Timur and subsequent enfeeblement of the Kingdom of Georgia, it soon faced a new threat. Timurid hegemony was not to last, for on Timur's death in 1405, the Kara Koyunlu re- established their empire. They took advantage of the temporary weakness of Georgians and launched attacks against them, apparently in which, George VII was killed. In response Constantine I engaged Turkomans at the Battle of Chalagan, in which he was defeated and executed.
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According to the Cambridge History of the Bible, this was mainly because "the vernacular appeared simply and totally inadequate. Its use, it would seem, could end only in a complete enfeeblement of meaning and a general abasement of values. Not until a vernacular is seen to possess relevance and resources, and, above all, has acquired a significant cultural prestige, can we look for acceptable and successful translation."Lampe, G. W. H. (ed.) (1975) The Cambridge History of the Bible, vol.
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After the devastating invasions by Timur and subsequent enfeeblement of the Kingdom of Georgia, it soon faced a new threat. Timur's death in 1405 marked the beginning of the end of his Empire, unified only by fear and blood of the subjected peoples. Turkomans, particularly the Kara Koyunlu clan, were among the first to rebel against Shah Rukh who ruled most of the Persia and Mawerannahr. Qara Yusuf, ruler of the Kara Koyunlu, defeated Shah Rukh, captured Baghdad, and repulsed Timurids from western Persia.
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The vizier () was the senior minister of the Fatimid Caliphate for most of the Egyptian period of its existence. Originally it was held by civilian officials who acted as the chief civilian ministers of the caliphs, analogous to the original Abbasid model. When a vizier was not appointed, an "intermediary" () was designated instead. The enfeeblement of the caliph's power and the crisis of the Fatimid regime under Caliph al-Mustansir, however, led to the rise of military strongmen, who dominated the post from the 1070s until the Caliphate's end.
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Around 1256, or, according to a different opinion, after the recapture of Constantinople in 1261, the island's government was entrusted to John Palaiologos, the younger brother of Emperor Michael VIII Palaiologos (). Nevertheless, already , the increasing threat of Turkish raids led Michael VIII to grant Rhodes to John de lo Cavo, a Genoese corsair in Imperial service, as a fief. Western, and specifically Genoese, interest in Rhodes did not abate. With the rapid enfeeblement of the restored Byzantine Empire under Andronikos II Palaiologos (), the Western powers hatched new plans to seize the strategically situated island.
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The three signs of multiple sclerosis now known as Charcot's triad 1 are nystagmus, intention tremor, and telegraphic speech, though these are not unique to MS. Charcot also observed cognition changes, describing his patients as having a "marked enfeeblement of the memory" and "conceptions that formed slowly". He was also the first to describe a disorder known as Charcot joint or Charcot arthropathy, a degeneration of joint surfaces resulting from loss of proprioception. He researched the functions of different parts of the brain and the role of arteries in cerebral hemorrhage. Charcot was among the first to describe Charcot–Marie–Tooth disease (CMT).
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It was at first thought > that this was an exclusively Jewish disease because most of the cases at > first reported were between Russian and Polish Jews; but recently there have > been reported cases occurring in non-Jewish children. The chief > characteristics of the disease are progressive mental and physical > enfeeblement; weakness and paralysis of all the extremities; and marasmus, > associated with symmetrical changes in the macula lutea. On investigation of > the reported cases, they found that neither consanguinity nor syphilitic, > alcoholic, or nervous antecedents in the family history are factors in the > etiology of the disease. No preventive measures have as yet been discovered, > and no treatment has been of benefit, all the cases having terminated > fatally.
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The first attempt to establish a set of diagnostic criteria was also due to Charcot in 1868. He published what now is known as the "Charcot Triad", consisting in nystagmus, intention tremor, and telegraphic speech (scanning speech)R. Milo, A. Miller, Revised diagnostic criteria of multiple sclerosis, Autoimmunity Reviews 13 (2014), 12 January 2014, 518–524 Charcot also observed cognition changes, describing his patients as having a "marked enfeeblement of the memory" and "conceptions that formed slowly". Diagnosis was based on Charcot triad and clinical observation until Schumacher made the first attempt to standardize criteria in 1965 by introducing some fundamental requirements: Dissemination of the lesions in time (DIT) and space (DIS), and that "signs and symptoms cannot be explained better by another disease process".
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Having observed that most actinomycetales are saprophytes, that is able to survive outside of living organisms, with the help of a veterinary, Camille Guerin, he attempted to create a special nutritious environment for the bacillus that, in time, altered its features by eliminating the virulence and leaving only the antigenic power. Both of the scientist knew that this arduous task would require a lot of effort and time, because it was necessary to act on a large number of generations to change the genetic foundation of a species, nevertheless the velocity of the bacteria's reproduction allowed, since it was constantly monitored, to interfere with an important phase of its evolution. The environment deemed appropriate for the denaturation of the Mycobacterium bovis was a compost of potatoes cooked in the bile of an ox treated with glycerine, and Calmette re-inseminated it every three weeks for thirteen years, while checking for an enfeeblement of the pathogenic power of the bacillus. Having finally lost completely its virulence, the bovine tuberculosis germ grown with their method was the principal prophylactic weapon against human tuberculosis, and it helped to reduce considerably the frequency of this disease.
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