The Russians are well-equipped and disciplined; the Syrians are dishevelled.
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The man, who offered his name as Theodore, was extremely dishevelled.
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There was anti-grooming, which involved fake sweat and dishevelled bed hair.
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Limp Bizkit were big, not doe-eyed boys singing with dishevelled ennui.
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The dishevelled man shrugged and walked away, gathering his ragged coats around him.
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Errol's discomfort increased until he felt compelled to account for his dishevelled appearance.
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The pair appear dishevelled and both break down crying during the 13-minute video.
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On the set, Tewksbury was a fanatic: wiry, dishevelled, intense, and a little terrifying.
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Sitting behind a desk in a maroon polo shirt, he appeared drawn, serious and dishevelled.
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Most students had a shambolically rustic look: boots, jeans, oversized checked shirts and dishevelled hair.
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He followed her into a dishevelled sitting room, where open books covered an octagonal table.
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"Two billion people on this earth less than a hundred years ago," the dishevelled man says.
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I wanted the blond trucker to see me like that, freshly bathed and a bit dishevelled.
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On the other side of the table sat Cohen's main defense attorney, Martin Klotz, looking slightly dishevelled.
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Mr Trump's dishevelled chief strategist, Steve Bannon, a self-described nationalist populist, has similar views, with a twist.
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In committee, in her slightly dishevelled philosopher's clothes, she simply tried to induce public servants to think rationally.
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There I meet some lads on the platform, somewhat dishevelled but still in their suits from the night before.
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But the EU should not give up on its dishevelled inner courtyard, if only because of the risks inaction poses.
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This was what Nunez had meant about his team having found a "different explanation" for Kolman's dishevelled state: a hookup.
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Such terms are rooted in the cult of the male artist—the dishevelled Beethovenian loner who conquers an indifferent world.
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Between all the sets were visions of Chicago's own brand of festival-goer: determined, dishevelled, and occasionally clad in banana suits.
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The man who led the facsimile project, a proudly dishevelled Englishman named Adam Lowe, was admiring the fake walls alongside me.
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Cobija, a dishevelled district capital 1,000km from the ocean, is the name of a Chilean fishing village that was Bolivia's main seaport.
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He was in his fifties, with a heavy red face, dishevelled hair, and a bushy mustache going from strawberry blond to white.
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"Night of the Blond Knives," said The Sun, Britain's most-read newspaper, in reference to the colour of Johnson's dishevelled mop of hair.
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One of the boats was filling up with dishevelled-looking men, who waved goodbye to a gaggle of women gathered on the embankment.
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" On one occasion, as Johnson made yet another grand, dishevelled appearance at a news briefing, a French reporter asked, " Qui est ce monstre ?
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The dishevelled Spanish combo guard looks like he just woke up from a bender, but there's an electric offensive game behind his laid-back demeanor.
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He said he had been offered up to $100,000 for interviews and been ambushed by paparazzi whose snaps had shown him buying beer and looking dishevelled.
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The Baartmans and Siegel show But, while designers opt for an artfully-dishevelled look, enhanced through artificial means; the look on the street is considerably less polished.
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LOOKING SOMEWHAT dishevelled and sometimes confused, the leader of Islamic State (IS), Abu Bakr al-Baghdadi, issued his first video message in five years on April 210th.
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Attended by only a faithful butler, since all the other servants have fled, they remain there for days, penned in like sheep, growing nastier and more dishevelled.
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Vo, who is forty-two, with permanently dishevelled dark hair and a gently humorous kind of authority, has been involved in every aspect of the installation process.
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Confronted by a topless protester from Femen, a radical feminist group, as he cast his vote, a dishevelled Mr Zeman had to steady himself on a nearby table.
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Her rival is a dishevelled septuagenarian with, according to the Committee for a Responsible Federal Budget, a hole of at least $3 trillion in his health-care plans.
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The only individual Jane Click was now aware of with any regularity was Theodore, who remained dishevelled in a way that seemed unsustainable even here, even within Dove.
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Then there's the dishevelled, Partagás-smoking Finn, who makes an offhand reference to the "Act of '53" as a law deals with the citizenship status of artificial intelligences.
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The designers at men's fashion week in London, which ended Monday, were unified in their approach to men's beauty, with models rocking a dishevelled, just-out-of-bed look.
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Nolan told us he took over a dishevelled unit in Crumlin, Dublin, in 2015, only made $25 in his first Saturday of trading, and thought he had screwed up.
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He said he had agreed to the pictures because he hoped they would improve his image as previous paparazzi snaps had shown him buying beer and looking dishevelled, TMZ said.
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Bannasch and her team spotted a specific mutation, in a gene known as DISHEVELLED 2 or DVL2, in all of the bulldogs and Frenchies and in nearly every terrier (94 percent).
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Natalia, tanned as always, wearing a loose white dress, her hair long and dark and dishevelled—I saw her through the fog of my irritated eyes, which I couldn't stop blinking.
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It is a far cry from 2015, when he left a good shop in Dublin to take the keys to a dishevelled unit in Crumlin, with approximately $500 to his name.
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In his dishevelled garden my neighbor Has fourteen varieties of apples, Fourteen trees his wife put in as seedlings Because, being sick, she wanted something Different to do (different from being sick).
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LONDON (Reuters) - Oscar winner Charlize Theron and comedy actor Seth Rogen join forces in rom-com "Long Shot", playing an unlikely love pairing between a powerful politician and an unemployed dishevelled journalist.
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The fascination with Mr Houellebecq is partly to do with the dishevelled chain-smoking figure himself, who embodies a decadent ennui that the French admire, yet who repels them at the same time.
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Serious but friendly, a woman who rarely jokes but readily laughs, the Los Angeles artist Laura Owens, forty-seven years old, was pleasantly dishevelled in mom attire: shirt, baggy shorts, sneakers, big glasses.
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He went on doing this on stage, television and film, appropriately playing both Prospero and a mad pyschiatrist: an increasingly dishevelled figure with accusing eyes, modelling himself on largely unknown orators of the London streets.
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With his carefully ruffled blond hair and often dishevelled appearance, Johnson's disarming wit and charm have proved popular with the public and helped him to shrug off crises that might have ended others' political careers.
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During previous work, Dr Watson noticed that a mixture of 37 proteins from Nematostella, including several known to help either repair or destroy misfolded proteins, were used by the anemones to reorganise their dishevelled bundles.
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Wehrschuetz is a household name in Austria, known for his often dishevelled appearance as well as his reports from the former Yugoslavia, where he has been a correspondent since 1999 and he continues to work.
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In "The Triumph of Poverty" (2009), a crowd treks past a beat-up car in a rural scene; one of them is a dishevelled rich man whose dropped pants reveal that he is ass-backward.
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In the back, Skinner found diapers, an empty bottle of the opiate hydrocodone, an extra set of license plates, and a driver's license showing a thin white man in his late twenties, with dishevelled brown hair.
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BERLIN (Reuters) - Peter Altmaier once said he would never rise to the top tier of German politics because of his appearance — he is a huge man who seems perpetually dishevelled, with shirt untucked and tie askew.
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In the clip, Jumpei Yasuda addresses his family and says he cannot speak with them, his hair looking longer and more dishevelled than in a previous photo taken shortly before he went missing around July last year.
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Haynes, a trim, boyish fifty-eight, with dishevelled brindle hair, was standing at the epicenter of his newest drama: a small corner office, whose west-facing windows looked out on skyscrapers and a sliver of the Ohio River.
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So clean-cut does he seem as an actor, with that steady jaw and the disconcerting directness of his gaze, that when anything truly messy or emotionally dishevelled comes along we know for sure that battle will be joined.
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Johnson, known in Britain and beyond for his often outlandish persona and dishevelled mop of platinum hair, said his country would not turn its back on the world after Brexit and cast the United Kingdom as a cosmopolitan consumer of imports.
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A natural comedian known to all by his first name, the dishevelled Boris has expertly kept the nation guessing for years as to exactly how high he wanted to climb and what he would be prepared to do along the way.
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The rise to one of the four great offices of state was the latest twist in an eventful career for the man invariably referred to simply as "Boris", known in Britain and beyond for his clownish persona and dishevelled mop of platinum hair.
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And it would, in fact, be easy to believe that you had stumbled into a favorite watering hole of some quiet fishing village, were it not for the patrons, who are more or less the picture of millennial affect common on this industrial corner of Bushwick: artfully dishevelled hair, dirty white T-shirts, fading sleeves of tattoos.
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"I think about that night all the time," Jacob said, knowing already, in the first hours of Tamir's visit, that he wouldn't have whatever human quality was required to tell Tamir that his marriage was failing, or how dishevelled and disappointed he had become, how agnostic—how far from that best night of his life his life had travelled.
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Regardless of who anyone was or why anyone had come—for Stormzy, for Novelist, for The Kooks, for the university orchestra, or for Daithí's violin covers of "Hollaback Girl"—it felt like every single person would end up face-down in a public space or a Subway at 6 AM or putting a cone on the head of a statue, reduced to their most dishevelled and pure form, and entirely satisfied.
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Segment polarity protein dishevelled homolog DVL-3 is a protein that in humans is encoded by the DVL3 gene. This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
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The śikhā is tied back or knotted to perform religious rites. Only funerals and death anniversaries are performed with the śikhā untied or with dishevelled hair. Dishevelled hair is considered inauspicious, and represents times of great sorrow or calamity. In Hindu scripture, Draupadi took an oath in the assembly of the Kurus after she was molested by Dushasana that she would remain with dishevelled hair until the enemies were properly revenged.
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The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
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Her hair appears dishevelled and she wears the simple clothes of a beggar. Her breasts are dry.
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The dishevelled madman of the stage behind the scenes turned crafty, trickish, and wary to a degree.
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This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ domain binding motif in its C-terminus, with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue, and cancer progression.
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Dishevelled binding antagonist of beta catenin 2 is a protein that in humans is encoded by the DACT2 gene.
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Segment polarity protein dishevelled homolog DVL-1 is a protein that in humans is encoded by the DVL1 gene.
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The current model is that these act together to inhibit GSK-3 activity. Dishevelled is able to induce a secondary axis when overexpressed and is present at higher levels on the dorsal side after cortical rotation (Symmetry Breaking and Cortical Rotation). Depletion of Dishevelled, however, has no effect. GBP has an effect both when depleted and overexpressed.
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The whispers became a roar when resident curtain-twitcher Mrs Timmins claimed to have spotted a dishevelled fat man munching on a giant beetle.
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He earned his nickname al-Ashʿath ("the dishevelled") because he was known to have dishevelled hair.Madelung 1997, pp. 193 Prior to his embrace of Islam in late 631, al-Ash'ath launched an expedition against the tribe of Murad, whose members had killed his father Qays. However, his assault was repulsed and he was taken captive. In return for his release, he paid the Murad 3,000 camels as a ransom.
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It is suspected that the mutation, which is known to budgerigar breeders as the "feather duster budgerigar" mutation, caused unrestricted feather growth, resulting in the budgerigar's dishevelled appearance.
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Back at his studio, Pinglet climbs in just before his wife returns. She is very dishevelled from a traffic accident. The summonses arrive from the police. Pinglet sees Mme.
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Dishevelled (Dsh) is a family of proteins involved in canonical and non- canonical Wnt signalling pathways. Dsh (Dvl in mammals) is a cytoplasmic phosphoprotein that acts directly downstream of frizzled receptors. It takes its name from its initial discovery in flies, where a mutation in the dishevelled gene was observed to cause improper orientation of body and wing hairs. There are vertebrate homologs in zebrafish, Xenopus (Xdsh), mice (Dvl1, -2, -3) and humans (DVL-1, -2, -3).
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Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins.
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Frizzled is a family of G protein-coupled receptor proteins that serves as receptors in the Wnt signaling pathway and other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol.
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Genetic studies have linked the autosomal recessive form of the disorder to the ROR2 gene on position 9 of the long arm of chromosome 9. The gene is responsible for aspects of bone and cartilage growth. This same gene is involved in causing autosomal dominant brachydactyly B. The autosomal dominant form has been linked to three genes - WNT5A, Segment polarity protein dishevelled homolog DVL-1 (DVL1) and Segment polarity protein dishevelled homolog DVL-3 (DVL3). This form is often caused by new mutations and is generally less severe than the recessive form.
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Muhammad made mention of a person who travels widely, his hair dishevelled, and covered with dust. A similar version in Hadith reported by Ahmad, Muslim, and al- Tirmidhi from Abu Hurayrah, as mentioned in sahih al-Jami #2744.
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The Dhumavati Tantra describes her as an old and ugly widow. She is thin, tall, unhealthy, and has a pale complexion. She is described as restless and wicked. Unadorned with jewellery, she wears old, dirty clothes and has dishevelled hair.
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De Gaulle's use of obscure vernacular profanity in a major speech was initially mistranslated by The Guardian and the English press corps as chien lit - dog bed, alluding to a chaotic, dishevelled, malodorous, flea pit, as in the English expression "a dog's breakfast".
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Catfights are often described as titillating for heterosexual men. Portrayals of catfights in cartoons, movies and advertising often display participants as attractive, with "supermodel physiques," dishevelled and missing articles of clothing, and catfights are often described by media aimed primarily at men as sexy.
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One of the first discovered examples of a highly dynamic intracellular liquid biomolecular condensate with a clear physiological function were the supramolecular complexes (Wnt signalosomes) formed by components of the Wnt signaling pathway. The Dishevelled (Dsh or Dvl) protein undergoes clustering in the cytoplasm via its DIX domain, which mediates protein clustering (polymerisation) and phase separation, and is important for signal transduction. The Dsh protein functions both in planar polarity and Wnt signalling, where it recruits another supramolecular complex (the Axin complex) to Wnt receptors at the plasma membrane. The formation of these Dishevelled and Axin containing droplets is conserved across metazoans, including in Drosophila, Xenopus, and human cells.
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Nkd proteins consist of at least four well-conserved blocks of amino acid sequence interspersed by variable regions.Wharton KA Jr, Zimmermann G, Rousset R, Scott MP. Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling. Dev Biol. 2001 Jun 1;234(1):93-106.
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The function of DEPDC5 is not yet known, but it has been implicated in intracellular signal transduction based on homology between the DEP domains of DEPDC5 and Dishevelled-1 (DVL1). Mutations in this gene have been associated to cases of focal epilepsy (doi:10.1038/ng.2601).
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Many other proteins also comprise the NMJ, and are required to maintain its integrity. For example, MuSK also binds a protein called "dishevelled" (Dvl), which is in the Wnt signalling pathway. Dvl is additionally required for MuSK-mediated clustering of AChRs, since inhibition of Dvl blocks clustering.
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Tim Westwood presents a special edition of Pimp My Ride in which he visits an old people's home in Staffordshire and then pimps their dishevelled 12-year-old LDV community transport bus. The finished bus came complete with waterproof seating, a walking stick rack and an onboard bingo hall.
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Generally of a dishevelled appearance, he used green moss and leaves taken from trees as clothing. As implied by his name, he had black hair; he was of a small stature. His fondness of children is similar to that displayed by the little known Hyter sprite of English mythology.
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Ascagne gallops across the stage on horseback. Didon and Énée have been separated from the rest of the hunting party. As a storm breaks, the two take shelter in the cave. At the climax of the storm, nymphs with dishevelled hair run to-and-fro over the rocks, gesticulating wildly.
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Monro took little pride in his personal appearance and was described by contemporaries as dishevelled, scruffy and even dirty. This was an era when many in medicine considered cleanliness to be finicking and affected. "An executioner might as well manicure his nails before chopping off a head."Gordon, Richard (2001) p.
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Dsh relays complex Wnt signals in tissues and cells, in normal and abnormal contexts. It is thought to interact with the novel protein, SPATS1, when regulating the Wnt Signalling pathway. Dishevelled plays important roles in both the embryo and the adult, ranging from cellular differentiation and cell polarity to social behavior.
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She notices the same man again when he delivers a pizza to her house. In the campus, she finds that he always seems to be falling asleep while at work. Becoming curious about this middle-aged dishevelled-looking man called Shigeru Matsumoto (Somegoro Ichikawa), she decides to film him for a class project.
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Jago 2015, p.419 As early as 1938, Chips Channon had called his clothes "truly tragic" and as he grew older, Butler acquired an ever more dishevelled appearance. He ate and drank copiously as Master of Trinity, causing him to put on weight and begin to suffer from heart problems.Howard 1987, p. 355.
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Meanwhile, Manni spots the homeless man from the subway passing by on a bicycle with the money bag. Manni steals back the bag at gunpoint, giving the man his gun in exchange. Lola arrives to witness Manni handing off the money to his boss. Manni joins Lola, who is dishevelled and perspiring.
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In the late antique Testament of Solomon,Testament of Solomon 58–59, translation and introduction by F.C. Conybeare, Jewish Quarterly Review 11 (1898), p. 30 online. Abyzou (as Obizuth) is described as having a "greenish gleaming face with dishevelled serpent-like hair"; the rest of her body is covered by darkness.Barb, "Antaura," p. 9.
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Willene is shocked at the dishevelled appearance of Mrs. Hammond and insist on giving her a bath. Willene explains that her husband is a very famous yet untalented country music star, Simon Cassidy, whose music is heard on the radio during the later scene. During the course of the bath, Willene unintentionally masturbates Mrs. Hammond.
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Naked cuticle 1 (NKD1) is a human gene that encodes the protein Nkd1, a member of the Naked cuticle (Nkd) family of proteins that regulate the Wnt signaling pathway.Wharton KA Jr, Zimmermann G, Rousset R, Scott MP. Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling. Dev Biol. 2001 Jun 1;234(1):93-106.
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Yan D, Wallingford JB, Sun TQ, Nelson AM, Sakanaka C, Reinhard C, Harland RM, Fantl WJ, Williams LT. Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3802-7. Katoh M. Molecular cloning, gene structure, and expression analyses of NKD1 and NKD2. Int J Oncol.
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After the run-in with zombified Calvin, Nick, Madison, and Travis choose to flee to the desert, and they want Alicia, Liza, and Chris to follow. Alicia finds Matt ill in his dishevelled house. Travis arrives and sees a bite on Matt, who convinces Alicia to leave. The group returns to Madison's home to gather supplies.
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Secreted proteins and cell surface receptors includes neurotrophins and tyrosine kinase receptors, BMP7, Wnt/dishevelled, EPHB 1-3, Semaphorin/plexin-neuropilin, slit-robo, netrin-frazzled, reelin. Rac, CDC42 and RhoA serve as cytoskeletal regulators and the motor protein includes KIF5, dynein, LIS1. Important secretory and endocytic pathways controlling the dendritic development include DAR3 /SAR1, DAR2/Sec23, DAR6/Rab1 etc.
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The Baroness now arrives, followed by all of the duellists' exhausted seconds. They denounce the Countess, but she convinces them individually that each is still her favourite. The suitors tell the Countess that the Commander has been seriously wounded by the Chevalier. He enters, bandaged and dishevelled, and ashamed to have lost the duel for the Countess.
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However, a dishevelled Boris now enters, echoing Shuysky: "Begone child!" The boyars are horrified. After Boris comes to his senses, Shuysky informs him that a humble old man craves an audience. Pimen enters and tells the story ("One day, at the evening hour") of a blind man who heard the voice of the Tsarevich in a dream.
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Winehouse's father and manager then sought to have her detained under the Mental Health Act of 1983. Her dishevelled appearance during and after a scheduled club night in September 2008 sparked new rumours of a relapse. Photographers were quoted as saying she appeared to have cuts on her legs and arms. According to her physician, Winehouse quit using illegal substances in 2008.
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In November 1985, Mervyn Rundle, then a 10-year-old altar boy in Donnycarney, Dublin, came to Naughton's house. Upon returning home, he told his mother that the priest was "a queer". The boy offered his dishevelled clothes as proof, saying Naughton had touched him sexually. Mrs Rundle telephoned her husband and told him to come home from work immediately.
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Naked cuticle 2 (NKD2) is a human gene that encodes the protein Nkd2, one of the Naked cuticle (Nkd) family of proteins that regulate the Wnt signaling pathway. Both Nkd1 and Nkd2 proteins can bind to Dishevelled proteins (DVL1, DVL2, DVL3), but only Nkd2 can bind to the EGF-ligand family member TGF alpha and regulate its polarized secretion in cultured epithelial cells.
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300px Self-portrait with dishevelled hair, Self portrait as a Young Man, and various other titles, is an early self-portrait by the Dutch artist Rembrandt, now in the Rijksmuseum. It dates to 1628 and is an exercise in chiaroscuro. It is one the earliest of over 40 painted self-portraits by Rembrandt.White, Christopher, Buvelot, Quentin (eds), Rembrandt by himself, pp.
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Prickle is recruited to the cell surface membrane by strabismus, another planar cell polarity protein. In the developing Drosophila wing, prickle becomes concentrated at the proximal side of cells. Prickle can compete with the ankyrin-repeat protein Diego for a binding site on Dishevelled. In Drosophila, prickle is present inside cells in multiple forms due to alternative splicing of the prickle mRNA.
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Humphries' character Sir Les Patterson is a boozy Australian cultural attaché: dishevelled, uncouth, lecherous and coarse. He alternates with Edna and Sandy Stone in Humphries' stage shows and typically features in pre-recorded segments in Dame Edna's TV shows. He is the polar opposite of Dame Edna; she a culturally aspirational Protestant from Melbourne and he a culture-free Roman Catholic from Sydney.
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While walking through the city, Gabriel receives a vision about the whereabouts of his comrade Uriel (Harry Pavlidis). However, the leader of the Fallen, Sammael, senses Gabriel's presence and sends the Fallen Molloch (Goran D. Kleut) to kill him. Gabriel fights and kills Molloch, then proceeds to the city's outskirts. He finds a dishevelled and alcoholic Uriel hiding in a rundown bus.
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Irena returns to her apartment looking dishevelled and exhausted; she is shown shortly afterwards weeping in the bathtub. Irena dreams of Dr. Judd dressed up as King John speaking of "the key". She later steals the key to the panther's cage in Central Park. Irena, Oliver and Alice visit a museum, and Irena is angered when the two virtually ignore her.
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After Wnt binds, an intracellular protein named Dishevelled (Dvl) is activated via phosphorylation. β-catenin degradation complexes in the cytoplasm are composed of adenomatous polyposis coli (APC), glycogen synthase kinase 3β (GSK3β) and Axin. APC promotes the degradation of β-catenin by increasing the affinity of the degradation complex to β-catenin. Axin is a scaffolding protein which holds the degradation complex together.
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In 1997, Gillian Wearing won the annual Turner Prize. In 1998, Chris Ofili won the annual Turner Prize. In 1999, Tracey Emin was nominated for the Turner Prize. Her main exhibit, My Bed, consisting literally of her dishevelled, stained bed, surrounded by detritus including condoms, slippers and soiled underwear, created an immediate and lasting media impact and further heightened her prominence.
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Giles identifies the body as an old friend from London, Philip Henry. The body has a tattoo, which Giles claims he does not recognize. Shaken, Giles does not meet Buffy at the hospital, and she battles the doctor-dressed vampires alone until Angel shows up. She goes to check on Giles who looks dishevelled and appears to have been drinking.
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Phil is blackmailed into signing The Albert over to Vincent Hubbard (Richard Blackwood), forging Sharon's signature. Sharon is angry but Phil pacifies her by revealing he has traced her father, now going by the name of Gordon Cook (Stephen Marcus). Gordon is a dishevelled man living in a run-down house. Phil persuades Sharon not to pursue meeting Gordon, but she changes her mind and visits him.
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DDX3X promotes CK1ε-mediated phosphorylation of Dishevelled (Dvl) in the canonical Wnt pathway but has also been demonstrated to stimulate CK1δ- and ε-specific kinase activity by up to five orders of magnitude. On the contrary, proteins being homologous to CK1BP (e.g. dysbindin or BLOC-1 [biogenesis of lysosome-related organelles complex-1]) are able to inhibit CK1δ kinase activity in a dose dependent manner.
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The lead track "Icehouse" had been written by Davies when he lived at 18 Tryon Road, Lindfield in an old, cold flat of a two-storey mansion – across the street was a dishevelled house which had its lights on all night peopled by short-term residents. Davies only learned it was a half-way house for psychiatric and drug rehab patients after he wrote the song.
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According to photographer Keith Morris by 1971 Drake was a "hunched, dishevelled figure, staring vacantly...ignoring the overtures of a friendly labrador or gazing blankly over Hampstead Heath." His sister recalled: "This was a very bad time. He once said to me that everything started to go wrong from [this] time on, and I think that was when things started to go wrong."Dann (2006), p. 157.
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The first, dating from 1898, was that of the family Onnis Devoto, by Sartorio. That of Faggioli contains three important paintings by Filippo Figari (1921). Also by Figari, the Larco monument, (1922) includes a painting by Figari, representing the Entombment of Christ. The painting caused controversy with Joseph of Arimathea pictured as a gravedigger, Mary Magdalene appearing dishevelled, and Christ's body stiff and rigid.
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Eva herself and her teenage daughter Gloria wore some dresses fashioned from Pag-asa cloth to show its versatility and practical use in daily activities. Dr. Macapagal is credited with transforming Malacañang from a dirty and dishevelled place to a clean and magnificent palace. Her training as a physician enabled her to bring about cleanliness and neatness in the rooms and appointments of the presidential residence.
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Before returning to Dublin in November 1949 he presented numerous manuscripts to the family, all of which are now believed to be in Spain. Kavanagh's personality became progressively quixotic as his drinking increased over the years and his health deteriorated. Eventually becoming a dishevelled figure, he moved among the bars of Dublin, drinking whiskey and displaying his predilection for turning on benefactors and friends.
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Key works include Hirst's The Physical Impossibility of Death in the Mind of Someone Living, a shark preserved in formaldehyde in a vitrine, and Emin's My Bed, a dishevelled double bed surrounded by detritus. The first use of the term "young British artists" was not by Michael Corris in a footnote in ArtForum, May 1992,Corris, Michael. "British? Young? Invisible? w/Attitude?.", ArtForum, May 1992, p. 109.
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Two music videos were produced for the song. The original video of "Be Mine!", directed by Brad Kluck and released in 2005, shows several Robyns (one bald, one a green-haired stripper, one with a bowl-cut and another dishevelled- looking one with white hair) featured in different scenes. Most of the different Robyns self-evaluate their appearance in some way, by looking into mirrors.
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She herself professed a liking for vintage clothing: > "When girls do the walk of shame ... I think they look best like that, > slightly dishevelled." The Kate Moss look? "Yeah".Sunday Times Magazine, 1 > January 2012 Some of the teenaged rock bands, such as Second SexSecond Sex took their name from the book of that name (1949) by Simone de Beauvoir. and the Plastiscines, that emerged in France c.
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Dev Biol. 2007 Nov 15;311(2):538-53. Epub 2007 Sep 15. 2) a single, extended EF hand motif (called "EFX" or "NH2") that binds Dsh/Dvl proteins;Yan D, Wallingford JB, Sun TQ, Nelson AM, Sakanaka C, Reinhard C, Harland RM, Fantl WJ, Williams LT. Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3802-7.
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Reid went to Belgium for 10 days before catching a train to Paris on 16 December. On 21 December 2001, Reid attempted to board a flight from Paris to Miami, Florida. His boarding was delayed because his dishevelled physical appearance aroused the suspicions of the airline passenger screeners. In addition, Reid did not answer all of their questions, and had not checked any luggage for the transatlantic flight.
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Rigor mortis has set in, forcing Rusk to break Babs's fingers to get the pin. Dishevelled and dirty, he gets out when the lorry stops at a roadside cafe. Babs's body is discovered when her leg is spotted sticking out of the back of the truck as it passes by a police car. Blaney, now the prime suspect in Babs's murder as well as the others, seeks out Rusk's help.
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Ashley is said to be a wheeler-dealer like his son. Ashley's arrival is reported to be due to difficulties in his personal life. An EastEnders insider is reported to have said "Fatboy has been a real hit with viewers and the bosses have decided that it's now time to bring in his dad so people can see what Fatboy is really all about." Ashley has been described as "dishevelled".
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The funnels riddled with bullet holes, the boats smashed and hull dirty and stained. Disembarking at Portsmouth dockyard, he stopped a civilian bus just outside the gates. Having looked at the dishevelled bunch in front of him, still with their weapons (and brandy), the bus conductor asked, "Are you just back from Dunkirk, sir?" The civilian passengers were still on board as the bus took the military personnel to Whale Island.
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During Life on Mars, Hunt often wore a beige camel coat with a white shirt and tie, grey suit and trousers with white slip on shoes, typical of the period. His top shirt button is always undone and his tie always hangs halfway down his chest in an untidy, dishevelled fashion. In Ashes to Ashes, he is often seen wearing a black suit, striped tie, Crombie coat and snakeskin boots.
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Commentary for "Homer Alone", in The Simpsons: The Complete Third Season [DVD]. 20th Century Fox. Susie Dietter served as assistant director for the episode and animated several of the scenes for the subplot with Bart, Lisa, Patty and Selma. In a scene where Homer sings a song to Maggie, he was designed to look dishevelled because the writers had wanted him to look drunk, although no attention was called to it.
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The film received rave reviews in the UK after its Royal Command Performance. The film has been characterised as "one of the best films ever about a painter".Rotten Tomatoes.com, The Horse's Mouth (1958), Ken Hanke – Mountain Xpress (Asheville, NC) Scott Weinberg of the "Apollo Guide" described Guinness’ performance as "a devilishly enjoyable character study" that "ranges from 'mildly dishevelled’ to 'tragically exhausted’" and also praises Ronald Neame's direction.
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The story concerns a dishevelled man in a filthy apartment. He is anxious and paranoid, trying to kill a small bug-like creature that is scurrying on the floor. It is revealed that the bug resembles a miniature version of himself, with every movement it makes being later matched by the man himself. He crushes the bug with his shoe, but is subsequently squashed by a larger version of himself.
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Self-Portrait with Dishevelled Hair (Rijksmuseum) is one of several works by Rembrandt bought for Dutch museums with assistance from the Vereniging Rembrandt. Vereniging Rembrandt (Rembrandt Foundation or Rembrandt Association) is a Dutch association of art patrons who raise funds to assist Dutch museums and art galleries in purchasing artworks. Since it was founded in 1883, it has helped purchase over two thousand works, including Vermeer's The Milkmaid.
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Standing behind the tree, she then provided Dufour with covering fire, allowing him to make his escape to hide in a friend's barn. Szabo fought the Germans for thirty minutes, killing a corporal, possibly more, and wounding some others. Eventually, she ran out of ammunition and was captured by two men who dragged her up the hill to a bridge over a railway. She was hot, dishevelled, and in pain.
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His costume is dishevelled and torn. He fights the minister, but breaks off when Tewke enters with other Puritans, who are armed and carry axes and lanterns. Lackland seizes an axe, but is immediately run through, to Tewke's dismay, by a pike carried by one of the Puritans. He dies in Marigold's arms; she kisses his brow, then stands and calls for vengeance and for her own death.
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It is of course always winter, when the chaperon was most likely to be worn. Saint Joseph is especially useful, as it is never part of his depiction to be fashionably dressed, and it is part of his character in the period that he is often shown quite dishevelled (see examples below). The shepherds are the lower-class figures most often shown in a large scale in paintings of the period.
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Everything is second hand, except the leviathan gin shops, which are ghastly in their newness and richness of decoration. The broad pavement presents a mixture of Vanity Fair and Rag Fair. It is the paradise of the lowest of costermongers, and often the saturnalia of the most emerited thieves. Women appear there in their most unloveley aspect: brazen, slovenly, dishevelled, brawling, muddled with beer or fractious with gin.
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This made her dishevelled and some of her supporters were dismayed, but this act revealed the stream that soon became a focal point for pilgrimages. Although it was muddy at first, the stream became increasingly clean. As word spread, this water was given to medical patients of all kinds, and many reports of miraculous cures followed. Seven of these cures were confirmed as lacking any medical explanations by Professor Verges in 1860.
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Epub 2010 Sep 19. Nkd1 binds to the Dishevelled (Dvl) family of proteins (DVL1, DVL2, DVL3). Specific truncating NKD1 mutations identified in DNA mismatch repair deficient colon cancer that disrupt Nkd1/Dvl binding implicate these mutations as a cause of increased Wnt signaling in approximately 1% of human colon cancer, the majority of which have increased Wnt signaling due to mutations the adenomatous polyposis coli (APC), AXIN2, or rarely the beta-catenin genes.
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It shows Townley in herm form – head and neck only, without full shoulders or arms – with a bare neck, dishevelled hair and a pensive expression. The National Heritage Memorial Fund, in whose 2008-9 annual report the bust is described as "masterfully executed", made a grant of £187,000 to help purchase the bust so that it could be returned to Towneley Hall Museum in the collector's former family home on the outskirts of Burnley.
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The noncanonical planar cell polarity (PCP) pathway does not involve β-catenin. It does not use LRP-5/6 as its co-receptor and is thought to use NRH1, Ryk, PTK7 or ROR2. The PCP pathway is activated via the binding of Wnt to Fz and its co-receptor. The receptor then recruits Dsh, which uses its PDZ and DIX domains to form a complex with Dishevelled-associated activator of morphogenesis 1 (DAAM1).
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The film begins with a shot in which a very dishevelled looking Abhijit (Abir Chatterjee) enters the room to find Debjani (Raima Sen) lying dead on the bed. The story goes back to a flashback and we get to see the reason behind such a fatal outcome. Abhijit is a professor of Mathematics at St. Xavier’s College, Kolkata. He lives with his only sister Mallika who is a crime journalist by profession.
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The difference between simple contractors and spellmasters is not clear and may be just a matter of experience. It is not known which demon made the contract, but it is implied to be a member of the royal family, as Hilda recognises the seal on his hand. He already had sealed the contract when he was in High School.Chapter 127 He wears a bandana, long, black dishevelled hair and is always seen smoking.
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Creepy people were thought to be more often male than female by an overwhelming majority of participants (around 95% of both males and females participants). Another study conducted by Watt et al. also found that participants associated the ectomorphic body type (more linear) with creepiness, more than the other two body types (51% vs mesomorphic, 24% and endomorphic, 23%). Other cues of creepiness included low hygiene, especially according to female participants, and a dishevelled appearance .
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Spermatogenesis associated serine rich 1 (SPATS1) is a protein which in humans is encoded by the SPATS1 gene. It is also known by the aliases Dishevelled-DEP domain interacting protein (DDIP), Spermatogenesis Associated 8 (SPATA8), and serin-rich spermatogenic protein 1 (SRSP1). A general idea of its chemical structure, subcellular localization, expression, and conservation is known. Research suggests SPATS1 may play a role in the canonical Wnt Signaling pathway and in the first spermatogenic wave.
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At the appropriate point in the flight, he would pretend to vomit loudly and violently into the bag. Then, to the horror of passengers and crew, he would proceed to eat the contents. One April Fools' Day Humphries placed a roast dinner and glass of champagne in an inner-city rubbish bin. Later in the morning, when there were many businesspeople queuing at a nearby building, Humphries approached the group as a dirty, dishevelled man.
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Two weeks later, Stan passes away from his cancer, devastating Cora. After his funeral, Cora departs, saying she will stay with Tanya in Exeter, and is then seen calling her and waiting for her to pick her up. A few months later, a dishevelled Cora attends a charity drive for the homeless at the community centre, but ensures nobody sees her. When Abi calls Tanya, she discovers Cora has not visited Tanya.
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Colin Weatherby is a Deputy Manager Wet and caretaker of Whitbury Leisure centre. Colin is a gentle, loyal and friendly character who is popular with all of his colleagues. However, he is also forgetful, disorganized, almost always late for staff meetings, highly incompetent and appears constantly dishevelled and filthy. However, Colin is a skilled carpenter and engineer and also has an impressive knowledge of biology, woodwork, construction, science, midwifery, plants, natural foods and healthy lifestyles.
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Along with Ken Yoshioka (harmonica) and Mike Robertson (steel guitar), Fauth formed the trio Dark Holler, named after a Clarence Ashley tune. They released the album Mother Earth (1998). In 2000, Fauth met Bob Mover and played alongside him for a while, before touring in Russia with Rotundo two years later. His debut album, Songs of Vice and Sorrow, was released by Electro-Fi Records in 2005, the cover of which depicted a dishevelled image of Buster Keaton.
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One document revealed that the Minister had ignored Planning SA's request not to make any commitments to the developers before the state's own 30-year plan was completed. South Australia's Planning Minister John Rau (2010–present) said that the Government should not have approved the rezoning of land without the government and council being able to support that community with infrastructure. The Government has since announced it will reform the state's planning process, calling it "dishevelled, disjointed and inconsistent".
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Scapigliatura () is the name of an artistic movement that developed in Italy after the Risorgimento period (1815–71). The movement included poets, writers, musicians, painters and sculptors. The term Scapigliatura is the Italian equivalent of the French "bohème" (bohemian), and "Scapigliato" literally means "unkempt" or "dishevelled". Most of these authors have never been translated into English, hence in most cases this entry cannot have and has no detailed references to specific sources from English books and publications.
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A very small species of marsupial, 45 to 58 millimetres in length. The fur is spiky and dishevelled in appearance, the upperparts are a mix of ginger and brown hairs, or grey-brown, with a rufous coloration across the flanks, ears and face. The eyes are close set and their muzzle is long and pointed. It rarely exceeds 58 mm in body length, with a tail 60 to 76 m long and a weight from 5.0 to 9.4 grams.
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The DEP domain derives its name from the proteins Dishevelled, Egl-10 and Pleckstrin, each of which contain a variant of this domain. It spans 82 residues and is 343 amino acids from the C-terminus. A SWISS-MODEL predicts two beta sheets and three alpha helices contained within the domain. While its exact function is not known, the DEPDC5 DEP domain has the highest structural similarity to the DEP domain of DVL1 when performing a CBLAST at NCBI.
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Kinsley (1997), p.176 Her hair is grey, her teeth crooked and missing, and her clothes old and worn.Kinsley (1997), p. 180 alt=A grey-scale image depicting woman wearing a sari and gold ornaments sitting on a chariot pulled by two large black birds and holding a winnowing basket. Sometimes, Dhumavati rides a crow and holds a trident. She may be depicted wearing a garland of severed heads, with red-coloured limbs and matted but dishevelled hair.
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In the 1930s she played Lady Macbeth and Queen Katherine in Henry VIII at the Shakespeare Memorial Theatre, Stratford-upon-Avon. In Gielgud's view, her most notable role of the inter-war years was Queen Elizabeth in Ferdinand Bruckner's Elizabeth of England: "In this play she showed unexpected tragic power in the scene in which Essex bursts into her presence to find her wigless and dishevelled."Gielgud, John. "Miss Phyllis Neilson-Terry", The Times, 30 September 1977, p.
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Lee had met him some years before while filming Tales of Hans Anderson, where he received his blessing. However, shortly before the wedding, Lee ended the engagement. He was concerned that his financial insecurity in his chosen profession meant that she "deserved better" than being "pitched into the dishevelled world of an actor." She understood, and they called the wedding off. Lee was introduced to Danish painter and former model Birgit "Gitte" Krøncke by a Danish friend in 1960.
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56 Bhikshatana is depicted with jatabhadra (dishevelled matted locks) or with jatamandala (matted hair arranged in a circle). A serpent may be depicted in his matted hair, which is also adorned by the crescent moon. His forehead bears a tripundara, the Shaiva tilaka composed of three horizontal lines of sacred ash with a red dot in the middle representing the third eye. He wears a patta (ornamental head band)—sometimes adorned with a human skull motif—on his forehead.
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Jang as the abused, chain smoking Sun- yeong in Sorum (2001), her first starring role for which she won several awards. Jang's first starring role was in the 2001 psychological horror film Sorum, in which she was cast against type as Sun-yeong, a chain smoking abused wife. The part required her to look badly bruised and dishevelled, and she found the regimen of three packets of cigarettes per day to be quite gruelling, despite being a smoker herself.Park Jeong-ho.
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Dalí's Rain Taxi, a former taxi, welcomed the visitors in the forecourt. The old automobile was covered with ivy inside and out, and a female dummy with dishevelled hair and dressed in an evening gown sat between some heads of lettuce and chicory in the back of the car. Next to her was a sewing machine. The driver was a doll, whose head was framed by the mouth of a shark and whose eyes were covered by a pair of dark glasses.
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In 1974 these murals were painted over at the order of a local bureaucrat. In 1972 he sold a painting to Tim Guthrie for less than $150. At a well known 1997 Sotheby's auction the same piece, "Water Dreaming at Kalipinypa" from the Tim Guthrie Collection of Early Western Desert Paintings sold for $206,000 to a Californian buyer for the record sum of $206,000 against an estimate of $50,000–$80,000. Warangkula was featured in the press as a dishevelled starving artist.
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With a new identity as the HTAV, during the 1980s the association continued to evolve towards its current form. Perhaps the most enduring legacy was the 1986 acquisition of a permanent address for the organisation, 'The Bakery' at 402 Smith St, Collingwood. This premise has remained the association's home for nearly twenty years and would be barely recognisable by those who knew it then. Somewhat dishevelled, it was transformed in 2003 to include carpets, air-conditioning and retail outlets below.
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Taylor's wife reported that when he arrived home on foot, he appeared dishevelled and muddy with torn clothing and ripped trousers. His wife called the police and a doctor, who treated him for grazes to his chin and thighs. Police accompanied Taylor to the site where he claimed he received his injuries. They found "ladder-shaped marks" in the ground where Taylor said he saw the large spherical object and other marks that Taylor said were made by the smaller, mine-like objects.
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My Bed by Tracey Emin (1998) My Bed is a work by the English artist Tracey Emin. First created in 1998, it was exhibited at the Tate Gallery in 1999 as one of the shortlisted works for the Turner Prize. It consisted of her bed with bedroom objects in a dishevelled state, and gained much media attention. Although it did not win the prize, its notoriety has persisted. It was sold at auction by Christie’s in July 2014 for £2,546,500.
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Aubry warns George that he must keep watch over Emmy - but already she is being led into the forest by Ruthven. Scene 4: Outside the inn Blunt, Gadshill, Scrop and Green sing of the pleasures of drink. Blunt's wife Suse upbraids the men, to the delight of the onlookers, but a dishevelled George arrives, recounting how he followed Emmy and "Marsden", only to find him standing over her dead body. He had shot the Earl immediately, leaving him to die in the moonlight.
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She plods along in a constantly dishevelled state, but has a calculating mind and, despite her irascible personality, she cares deeply about her work and colleagues. She often proves her superior skills by picking up small errors in her co-workers' thought processes. Vera forms a close relationship with sergeants Joe Ashworth (David Leon) and Aiden Healy (Kenny Doughty). On 27 August 2020, it was confirmed that the show had been renewed for an eleventh series, which will air in 2021 and 2022.
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Although the targets of CK2 are predominantly nucleus-based the protein itself is localized to both the nucleus and cytoplasm. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathway activation. A Pertussis toxin-sensitive G protein and Dishevelled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of CK2. Further studies need to be done on the regulation of this protein due to the complexity of CK2 function and localization.
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He was bare- bodied and his hair was dishevelled when the attack occurred. Lü Bu and his wife escaped by climbing over the wall and then they fled to the camp of Gao Shun, one of Lü's subordinates. Lü Bu told Gao Shun about the Henei accents he heard, and Gao Shun deduced that the rebel leader was Hao Meng. Gao Shun then led his troops to Lü Bu's office and drove the rebels away by firing arrows at them.
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Her performance qualifies her for heavy- duty roles." Upon release, the film, which was made on a budget of $26million, earned over $95million at the worldwide box office. In late 2005, McAdams starred with Sarah Jessica Parker and Diane Keaton in the seasonal family comedy-drama The Family Stone, which gave McAdams an opportunity to play a dishevelled and sardonic sister, rather than the usual "obvious" girlfriend or wife roles. She was eager to work with Keaton and remarked, "It's never about line counts for me.
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While a teacher is on sick leave, despite his dishevelled appearance and an employment history with unexplained gaps, Daniele is hired to take a class in Rimini. To get to know his pupils, he asks them to write a free essay or, if they prefer, one on the writer Manzoni. To his surprise, only one chooses the latter, the quiet and very attractive Vanina, who increasingly absorbs his attention. He talks to her when he can and gives her the book Vanina Vanini by Stendhal.
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Six youths ditch school for the woods, where some hotrodding on a stolen moped changes the fate of their day. They crash into Peter, a dishevelled drifter, who is delighted to have a group of teens to hang out with. First he gains their trust by joining in their games, but then his behaviour changes. Peter uses what he has learned about the kids against them, bullying the alpha boys, belittling the weaker ones and saving his worst for the only girl in the group.
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In resting cells, axin molecules oligomerize with each other through their C-terminal DIX domains, which have two binding interfaces. Thus they can build linear oligomers or even polymers inside the cytoplasm of cells. DIX domains are unique: the only other proteins known to have a DIX domain are Dishevelled and DIXDC1. (The single Dsh protein of Drosophila corresponds to three paralogous genes, Dvl1, Dvl2 and Dvl3 in mammals.) Dsh associates with the cytoplasmic regions of Frizzled receptors with its PDZ and DEP domains.
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The film is set in and around a bird-hide on the Suffolk marshes owned by Roy Tunt (Macqueen). Roy is a middle-aged, obsessive bird watcher, who needs just one more sighting (of the sociable plover) to complete the entire British list of birds. He is unexpectedly joined by a dishevelled and tattooed stranger, who introduces himself as Dave John (Campbell). After an awkward start, the pair build up a rapport, share lunch, have a drink and discuss a wide variety of subjects.
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Lauren calls Ned while he is at the airport; he initially ignores her calls, but Ms. Hampton appears and forces him to answer his phone. He and Lauren reconcile and she tells him that they must marry on the Tiwi Islands. Ned persuades Ms. Hampton to skip a day at work and come to the wedding, as he is grateful for her continuous support of Lauren and Trevor. Ned rushes back to Trevor's house and encourages him to come to his daughter's wedding, despite his dishevelled state.
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Goopy Geer snaps his fingers madly, and produces a rhythm by pulling a lever on and thereby releasing the ash from his new dance-partner, the stove. A dishevelled villain enters with a shotgun; he lowers at Goopy's sweetheart, whereupon Goopy orders him to stand back. This challenge is met with shotgun bursts and our hero staggers back from the scene, stepping in a pair of spitoons and falling back on the table. He frees the spitoons from his feet, flinging them at the cackling cad.
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Li Qing thus cremated Li Tieguai's body. He passed by a dying beggar on his way to his mother's but did not have time to bury him. Upon returning, Li Tieguai's spirit found that his body had been cremated and had to enter the only body available at the time, the corpse of the homeless beggar who had just died of starvation. The beggar, unfortunately, had a long and pointed head, large ears with one large brass earring, a woolly and dishevelled beard and hair.
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Ridiculusmus is an award-winning British theatre company founded in 1992 by Angus Barr, Jon Haynes and David Woods. Their work has been described as "seriously funny," "Dadaist" and "physical theatre." Theatre critic Ian Shuttleworth said that Ridiculusmus is "not so much rough theatre as completely dishevelled." Since 1996, the company has been led by Haynes and Woods as co-directors, and although the majority of their stage works in recent years have been two-handers, they additionally work with a large pool of collaborators.
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Ashes is an oil on canvas painting by the Norwegian symbolist painter Edvard Munch. Painted in 1894-95 it is now in the collection of the National Gallery of Norway in Oslo. The work depicts a critical scene in a lovemaking tryst between a couple in the forest, which has left the man hunched over in shame or dejection and the dishevelled woman wide-eyed and motionless in frustration or despair. The picture's title suggests that, for whatever reason, the heat of their passion had burnt out at that moment.
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1991: Charles Saatchi funds Damien Hirst and the next year in the Saatchi Gallery exhibits his The Physical Impossibility of Death in the Mind of Someone Living, a shark in formaldehyde in a vitrine. 1993: Vanessa Beecroft holds her first performance in Milan, Italy, using models to act as a second audience to the display of her diary of food. 1999: Tracey Emin is nominated for the Turner Prize. Part of her exhibit is My Bed, her dishevelled bed, surrounded by detritus such as condoms, blood- stained knickers, bottles and her bedroom slippers.
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During her relationship with Cinque, she was dieting excessively and would obsess about her weight. Singh's problems appeared to stabilise briefly during the early days of her relationship with Cinque, but soon returned after they moved in together. Her university attendance became sporadic, and on the rare occasion when she was seen by her peers, she appeared to be "dishevelled" and "poorly dressed"—in contrast to her earlier generally immaculate and prideful dress sense. Singh's father took her to various psychologists and psychiatrists for help, who opined Singh's problem was "psychological", not physical.
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Mask of a Weeping Woman is a sculpture by Auguste Rodin, initially produced as a pair with Weeping Woman for the first version of his The Gates of Hell in 1885. The two pieces were intended to appear on the centre of each panel. They were later moved by Rodin himself, who instead placed Mask on the lower part of the left panel. In his 1909 retrospective catalogue of his own works, Rodin described this pair of works as a "face violently creased with sadness and torn by bitter tears and dishevelled hair".
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Three Wnt signaling pathways have been characterized: the canonical Wnt pathway, the noncanonical planar cell polarity pathway, and the noncanonical Wnt/calcium pathway. All three pathways are activated by the binding of a Wnt-protein ligand to a Frizzled family receptor, which passes the biological signal to the Dishevelled protein inside the cell. The canonical Wnt pathway leads to regulation of gene transcription, and is thought to be negatively regulated in part by the SPATS1 gene. The noncanonical planar cell polarity pathway regulates the cytoskeleton that is responsible for the shape of the cell.
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Upon activation of the receptor, a signal is sent to the phosphoprotein Dishevelled (Dsh), which is located in the cytoplasm. This signal is transmitted via a direct interaction between Fz and Dsh. Dsh proteins are present in all organisms and they all share the following highly conserved protein domains: an amino-terminal DIX domain, a central PDZ domain, and a carboxy-terminal DEP domain. These different domains are important because after Dsh, the Wnt signal can branch off into multiple pathways and each pathway interacts with a different combination of the three domains.
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In the Irish literary mind, wolves were particularly closely linked with the practices of the fianna, warrior bands of landless young men who lived for much of their time in the wilderness and were thought of as living in close proximity to supernatural forces. Warriors were often depicted with canine attributes and shared a common motif of a wild, dishevelled or naked appearance. They were frequently portrayed as wolves, hunting both animals and humans, and may have worn wolf-skins or a lupine hairstyle as part of a ritual transformation.Wyatt, pp.
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He therefore prepared to attack the island of Mona which had a powerful population and was a refuge for fugitives. He built flat-bottomed vessels to cope with the shallows, and uncertain depths of the sea. Thus the infantry crossed, while the cavalry followed by fording, or, where the water was deep, swam by the side of their horses. :On the shore stood the opposing army with its dense array of armed warriors, while between the ranks dashed women, in black attire like the Furies, with hair dishevelled, waving brands.
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Mario was born in São Paulo. Right after signing his first professional contract with Grêmio, Fernandes found it hard to adjust to a new home and fell into depression, prompting him to disappear to his uncle. The police found him in a dishevelled state nearly 700 miles from Porto Alegre, hungry and exhausted. In a later interview he refused to disclose why he made no attempt to contact the club during this time, but pointed out the difficulties of settling at the beginning of a career, citing the example of Jesús Navas.
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They would not meet again until 4 June 1989, when Chen went looking for Lan Yu, fearing for the youth's safety amid the army's Tiananmen Square crackdown. Finding Lan Yu dishevelled and distraught, the incident reunited the two and opened a new chapter in their relationship. Although Chen Handong still could not commit totally to Lan Yu, he now gave the youth time and attention as well as money, a car, and an expensive villa in the Beijing suburbs. None of the material things were what Lan Yu really wanted although he now accepted them.
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On 23 May 2020, Bhar took Pasi to a stream, where her dead body was found hanging from a tree in Devdaha, Rupandehi District, with "her shoes off her feet, her clothes torn, her hair dishevelled". The local residents believe that Pasi was murdered by Birendra Bhar's family. One resident noted that the tree was too tall for her to climb and hang herself, and "circumstantial evidence suggested other foul play". According to journalist Binod Pariyar, Bhar's family offered to suppress the case and prevent the involvement of police or human rights organisations.
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Wnt signalosome: Transduction of Wnt signals from the plasma membrane depends on clustering of LRP6 receptors with Dishevelled (Dvl) proteins to recruit the Axin complex for inactivation. B-cell receptor (BCR) signalosome: The B-cell receptor (BCR) binds antigen and undergoes clustering to induce signal transduction. T-cell receptor (TCR) signalosome: Antigen presentation to T-cells is recognised by the T-cell receptor (TCR), which initiates clustering and activation of downstream signalling to induce T-cell responses. COP9 signalosome: Catalyses the hydrolysis of NEDD8 protein from the Cullin subunit of Cullin-RING ubiquitin ligases (CRL).
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This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin (cadherin- associated protein) beta 1, glycogen synthase kinase 3 beta, protein phosphatase 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved.
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Determined to find the truth, F. leaves the hotel and heads toward the desert. On the way she finds Olsen's dead body next to his exploded Volkswagen van, and while she examines the disaster she meets the cameraman Polypheme, who is filming her. Polypheme tells F. that he has video footage of Sørensen, who was on the trail of a secret before her death, and offers to show it to F. if she allows him to make a film portrait of her. Despite his dishevelled appearance and apparent drunkenness, she agrees.
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DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for processes involved in cell transformations involved in neuroblastoma. The Schwartz-Jampel syndrome and Charcot-Marie- Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
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When they realise the intruder is not one of themselves, they attack it, stripping away the borrowed finery and leaving its so dishevelled that it is afterwards rejected by its fellows. The moral of the story is not to reach above one's station. Some mediaeval versions have different details. In Odo of Cheriton's telling the crow is ashamed of its ugliness and is advised by the eagle to borrow feathers from the other birds, but when it starts to insult them the eagle suggests that the birds reclaim their feathers.
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Pathologist Keith Simpson outlined his post-mortem examination, concluding that death was caused by "blunt head injuries" and "inhalation of blood". He confirmed that the lead pipe found at the scene was most likely responsible for Rivett's injuries; some, to the left eye and mouth, he thought more likely to have been caused by punches from a clenched fist. The last person to confirm seeing Lucan alive, Susan Maxwell-Scott, told the court that the earl looked "dishevelled", and his hair "a little ruffled". His trousers had a damp patch on the right hip.
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She then left for Lisbon, where she was the prima donna of an Italian opera buffa company led by Fioravanti. She performed in numerous operas at the Theatro de São Carlos between 1803 and 1805, including the world premiere of Fioravanti's La donna soldato. The young women in the São Carlos audiences were fascinated by her way of styling her thick blond hair to look artfully "dishevelled" and soon began imitating it. The Portuguese word "gaforina" was coined to describe both Gafforini's hairstyle and the type of woman who wore it.
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Epsin is thought to have role in the angiogenesis of tumors thus, epsin has the potential to be a target for anti-cancer therapies. Several cancers including prostate, breast, lung and skin display an up regulation in epsin. Research indicates that the overexpression could affect the regulation of tumor angiogenesis through defects in the notch pathway. There is also evidence that Epsin could lead to colon cancer through impaired Wnt Signaling by reducing the stability of the Wnt effector dishevelled, leading epsin to being a possible target for pharmaceuticals.
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It doesn't take long for the aliens to abduct the policeman, Jillian, and Riley, who is still clinging to the camera—the remaining footage shows a rapid ascension into orbit, and an in-time repeat of the same footage from the beginning of the film. Two men in respirators and Hazmat suits are seen taking the camera away in a U.S. Air Force van. In a mid-credits scene, Peter Morris is found one year later by a North Carolina state trooper. He is huddling on a bridge, naked, dishevelled and in a state of shock.
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Although all of the Pythons played women, Terry Jones is renowned by the rest to be 'the best Rat-Bag woman in the business'. His portrayal of a middle-aged housewife was louder, shriller, and more dishevelled than that of any of the other Pythons. Examples of this are the "Dead Bishop" sketch, his role as Brian's mother Mandy in Life of Brian, Mrs Linda S-C-U-M in "Mr Neutron" and the café proprietor in "Spam". Also recurring was the upper-class reserved men, in "Nudge, Nudge" and the "It's a Man's Life" sketch, and incompetent authority figures (Harry "Snapper" Organs).
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His round face was dominated by his luxuriant eyebrows, with the result that he was known among fellow Whigs as 'the Eyebrow.' Though he became increasingly dishevelled and fat in middle age, the young Fox had been very fashionable; he had been the leader of the 'Maccaroni' set of extravagant young followers of Continental fashions. Fox liked riding horses and watching and playing cricket, but his impulsive nature and considerable bulk led to his often being run out between wickets. Fox was extremely ridiculed – most famously by Gillray, for whom he served as a stock Jacobin villain.
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Billen conceded that his interpretation may be incorrect, and that the episode may have been a single "dying dream". McDowall noted that, with Christine's growing unhappiness and increasingly dishevelled appearance as the episode progresses, it is easy to see the story as about a mental collapse. The episode can also be seen as a story of revenge; it can be imagined that Christine has repressed the memory of her first boyfriend, and that he "has come back into her life seeking revenge". On this interpretation, the Stranger is the boyfriend, and causes the crash by stepping out in front of Christine's car.
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The protests against the skirt proposal marked the first representative actions of the Surf Bathing Association of New South Wales, the precursor to Surf Life Saving Australia, formed only days before on 18 October. Members of the Association, outraged by what they saw as their impending emasculation at the hands of the new bathing costume laws, organised the protest in less than two days. The rushed preparations undoubtedly accounted for the dishevelled state of dress in which many of the "ladies" appeared on the day. The beach protests were described as having a "carnival atmosphere", especially at Bondi.
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On a brief trip to London to meet the Wimsey family solicitor, Harriet is trapped in the basement of her old home by a sudden air raid, and is surprised to encounter a dishevelled Bunter, returned home from his and Peter's mission. He says he has no word from Peter. The following week, he appears at Talboys to resume service with the household, since he has been denied permission to re-enlist in the army because of his age. At the suggestion of Peter's sister Mary, Harriet summarises her progress in the murder investigation in letters to Peter, which she does not send.
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Over 240 productions took place in the Lancashire resort by a Yorkshire repertory during the war. The building in Townhead Street was eventually hired out for storage. At the end of the war, the Company was able to return to its natural home, although it owed a debt to Southport for its survival. The theatre was in a dishevelled condition, following its utilitarian usage during the war, but the Company, helped by willing volunteers successfully renovated the auditorium in 1945, allowing it to re- open to the theatre-going public, with the appropriately titled play, The Peaceful Inn.
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There they are locked in a cage-like room with a dishevelled man named Steven Taylor, an astronaut from Earth who crash-landed on the planet two years earlier and has been kept as a prisoner by the Mechonoids since then. The Daleks now attack the city. The Doctor and his party and Steven escape down some cables, while the Mechonoids and Daleks become involved in a pitched battle which devastates both sides as well as the building. The four companions flee to safety but are separated from Steven, whom they presume to have been killed.
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The story of a young man who is brought up in the forest by his mother because she does not want him to learn about chivalry and fighting, and who later arrives at King Arthur's court in an innocent and dishevelled state with the desire to be made a knight, is none other than an account of the childhood of Perceval. Chrétien de Troyes introduced Perceval at the beginning of his unfinished last romance, Perceval, le Conte du Graal, written between 1180 and 1190Kibler, William W and Carroll, Carleton W. 1991. Chrétien de Troyes: Arthurian Romances. Penguin Books Limited.
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On 19 May 2011, Jeloscek was hung up on during a phone interview with popular shock jock Ray Hadley on Sydney radio station 2GB. Hadley took offence that Jeloscek wanted to correct something he asserted was suggested on-air before the interview began, and Hadley cut off Jeloscek mid-sentence telling his listeners: Chief of staff to then Finance Minister Greg Pearce, Jo McCafferty, was involved in an altercation with Jeloscek at a drinks function in which a "dishevelled" McCafferty called Jeloscek a "bottom feeder". The incident reportedly related to a recent Seven News story criticising Greg Pearce.
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It portrays the unfinished outline of a young woman whose face gently gazes downward while her loosely drawn dishevelled hair waves in the air behind her. The woman's eyes are half-closed and completely ignoring of the outside world and viewer, while her mouth is slightly shaped into an ambiguous smile, evocative of the Mona Lisa. Other than her face that takes up most of the painting, the rest of the painting is barely even sketched in, with a primed but unpainted background. The differences in the face and the rest of the painting are effectively blended by a mastery of sfumato.
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The play premiered in January 1987 at the Théâtre Nanterre-Amandiers. It was presented on television in 1999 and that version was released on video in 1999. The play was performed in its original French at the Edinburgh Festival. Writing in The Independent, Paul Taylor said that despite his initial misgivings and prejudices--he anticipated "howling boredom"--he was won over by "a staging of impressive intensity", notably the "palpable magnetism between Pascal Greggory's tall, shaven-headed, vehemently fastidious Client and Patrice Chereau's smaller, dishevelled, professionally pleading Dealer" and the "formal stateliness and a verbal elaboration" at odds with the setting.
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Soon, the matter reaches the court of the new "King," who recognizes her husband despite his dishevelled and bewildered face. Prathap, however is unable to recognize the disguise of his wife and addresses her as the King. She decides to settle this dispute by asking the cobbler if he was happy to see the kingdom's new king. He responds positively, to which she replies that since this quarrel with the young man resulted in his visit to the new king, which ultimately made the cobbler happy, he should go back to his duties, since "happiness" was provided.
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Egyptian mourners inscribed on a tomb In ancient Egypt, the mourners would be "making an ostentatious display of grief which included loud wailing, beating exposed breasts, smearing the body with dirt and dishevelled hair; all signs of uncontrolled behavior, the disorder of sorrow" (Capel, 1996). There are many inscriptions on tombs and pyramids of crowds of people following a body throughout the funerary procession. However, the most important of the women were the two that impersonated the two gods Isis and Nephthys. Isis and Nephyts were both Egyptian gods that were believed to play a special role when someone died.
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Bandstand opened with "Burlesque", a straight rocker about a bar of that name in Chapman and Whitney's hometown of Leicester, England. Released as a single in the UK, it got up to number thirteen on the charts. Heavier songs on Bandstand included "Broken Nose", an angry sexual rant involving the British class structure, and "Ready To Go", a swipe at Family's detractors in the British rock press. Family also were becoming more adept with introspective tunes like "Coronation", about an apartment dweller ruminating about his neighbours and his own dishevelled flat, and "Dark Eyes," an atmospheric, sensual ballad Chapman wrote with Poli Palmer.
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Heyerdahl recounted how the captain of the expedition's ship wanted visiting aboriginal islanders to sign the ship's guestbook, but all of them refused. Figueroa attempted to get the crowd to comply, "[b]ut when he tried to give further explanations there was more and more disturbance around him...[Heyerdahl] had to use all of [his] authority to get Gonzalo out of the crowd, and he came back with the book, untidy and dishevelled."Heyerdahl, T. 1958: 51. The islanders had refused to sign because they believed that was how their ancestors had been tricked into being taken to Peru as slaves.
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Human Epac2 is coded by RAPGEF4 located at chromosome 2q31-q32, and three isoforms (Epac2A, Epac2B, and Epac2C) are generated by alternate promoter usage and differential splicing. Epac2A (called Epac2 originally) is a multi-domain protein with 1,011 amino acids, and is expressed mainly in brain and neuroendocrine and endocrine tissues such as pancreatic islets and neuroendocrine cells. Epac2A is composed of two regions, an amino-terminal regulatory region and a carboxy-terminal catalytic region. The regulatory region contains two cyclic nucleotide-binding domains (cNBD-A and cNBD-B) and a DEP (Dishevelled, Egl-10, and Pleckstrin) domain.
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The Doctor and Anne work on the control box further and successfully reprogram a control sphere, which they load into a disabled Yeti to make a covert, voice-controlled ally within the Intelligence's ranks. Staff-Sergeant Arnold, who turns up dishevelled and bleeding, having somehow survived, links up with the Colonel and Jamie in the tunnels. All three agree to return to HQ to support the Doctor, though they find that he and Anne have left while searching for a Yeti to reprogram. At that moment, the fungus bursts through the walls of HQ, swamping Goodge Street shelter.
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Monument to Menotti in Modena His father, who built musical organs, wanted him to follow in the profession, but the boy inclined towards art, and he received early mentorship from the sculptor Luigi Mainoni, professor of the Academy of Modena. At the Modenese Academy, he won all the contests, and garnered a stipend to study in Florence, and where he was helped by the sculptor Giovanni Duprè and Pietro Cantini. His first essay in sculpture, submitted back to Modena, was a stucco of Drunkenness, that is, a life-size, dishevelled Bacchante drinking. Then he sent a group of two figures, shepherds and sheepdog.
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In a second video released shortly after the first, Requesens appears dishevelled and in underwear stained with faeces. A third video was shared days later by Maduro, showing what the government claimed was another part of the "confession" from the first video. In the third video, Requesens is seen stating that Borges gave him the contact "Russo [...] who confirmed that Juan Monasterios was already in Colombia"; "Russo" refers to a suspect whose full name is Rayder Alexander Russo Márquez. El Nacional reported that journalist Javier Mayorca spoke to Vilca Fernández, a former political prisoner held at El Helicoide, in Peru.
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"Icehouse" is a song by the Australian rock band Flowers, later known as Icehouse. It was released as a single in Europe in 1982 by Chrysalis Records from the band's first album, Icehouse, after the band changed its name to Icehouse. In the United States, the song peaked at number 28 on the Billboard Top Tracks chart in 1981. "Icehouse" was written by founding member Iva Davies when he lived at 18 Tryon Road, Lindfield in an old, cold flat of a two-storey mansion—across the street was a dishevelled house which had its lights on all night peopled by short-term residents.
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In the engraving, symbols of geometry, measurement, and trades are numerous: the compass, the scale, the hammer and nails, the plane and saw, the sphere and the unusual polyhedron. Panofsky examined earlier personifications of geometry and found much similarity between Dürer's engraving and an allegory of geometry from Gregor Reisch's Margarita philosophica, a popular encyclopedia.Klibansky, Panofsky & Saxl, 315 Other aspects of the print reflect the traditional symbolism of melancholy, such as the bat, emaciated dog, purse and keys. The figure wears a wreath of "wet" plants to counteract the dryness of melancholy, and she has the dark face and dishevelled appearance associated with the melancholic.
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An apprentice Shaper is sent on a training mission with a Shaper Agent named Shanti by the Shaper Council. The pair are tasked with assessing the failed Shaper colony Drypeak and making contact with the pair of Shapers, Barzahl and Zakary, who were dispatched years ago to revitalize the colony. The gates of Drypeak are found unmanned, much to Shanti's disgust, the Agent and her charge are also attacked by rogue Shaper creations. When the pair gain access to the colony, they find a dishevelled Zakary who informs them that both he and Barzahl were unsuccessful in revitalizing the colony, which remains a barren desert.
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Maugham wrote: "... it had in the third act a scene in which the heroine had to appear dishevelled, with no make-up on, and have her hair done while she arranged her face before the audience. No actress would look at it...." Otho Stuart, at the Royal Court Theatre in London, had had an unexpected failure; needing a play during the time required to get another play ready, he accepted Lady Frederick. It was first produced there on 26 October 1907, with Ethel Irving as Lady Frederick. It transferred to the Garrick Theatre, the Criterion Theatre, the New Theatre and the Haymarket Theatre; it ran for 422 performances.
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An unmarried vicar, the Reverend Howard Phillips (Anthony Quayle), newly arrived in the parish, attempts to get local 19-year-old thug and petty criminal Larry Thompson (Andrew Ray) to face up to his responsibilities to Mary Williams (Leigh Madison), the naive young girl he has made pregnant. When Howard threatens to tell his coffee-bar friends, Larry trashes the room and fakes a struggle. As a dishevelled Larry leaves, Hester Peters (Sarah Churchill) arrives, and he tells her that Howard "interfered" with him. Hester is the daughter of the parish’s previous clergyman and has become infatuated with the athletic and handsome new vicar.
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Dishevelled and restless, Chimène enters followed by Elvire and her other ladies. She is in despair about the terrible choice she has been forced to make, but she strongly believes Rodrigue can never be defeated in combat. Rodrigue arrives to say goodbye for the last time and tells her that he will never dare to raise his sword against anyone who fights in her name. He will let himself be killed, with no fear for his honour: people will only say that, conquered by Chimène, and with no hope of changing her mind, he had preferred to die rather than live with the burden of her hatred.
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After meeting her mother, Sonya, he was then allowed to attend Ryan's 15th birthday party and stay overnight. After a shopping trip together, his increasingly erratic and possessive behaviour at the party, and inappropriate physical advances, he was told to leave by Ryan's mother Sonya, who then limited Ryan's mobile access. Later, on 19 February, Ryan left the house for an apparent sleepover with friends, but after not returning the next day, the police were notified. The same morning, at Horseshoe Bay in Port Elliot, Ryan's battered and dishevelled body was found floating face-down in the shallow water, and attempts to revive her failed.
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The king disliked the counsel of the first four owls. The fifth crow suggested that the crow king rip off some of the advisor's own feathers and attack him, leaving him in a dishevelled state, so that he could infiltrate the owl colony as a double agent. When the owls came upon the crow spy, they didn't know what to do with him, so the owl ruler consulted his advisors, one said to kill him but the other two were in favour of keeping him alive as an advisor. The first advisor was still adamant that they should kill the crow but he was ignored.
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Considered Villanelle's fashion foil by Entertainment Weekly, Eve Polastri has been described as considering fashion "trivial" and not bothering to dress well. Jennings suggested that even if she cared, "she'd be hopeless at it"; Mitchell and de Gaye crafted outfits that match Eve's practical attitude, with Mitchell saying that she "wears elastic waists [because] she doesn't have time to do up a button fly". Other choices include more clothes made of linen to more easily appear dishevelled. Eve is allowed some moments of being well-dressed, however, which are significant to the plot, including trying on dresses that Villanelle has chosen for her in her own stolen suitcase.
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Spotting a dishevelled figure resting from gathering firewood, intelligence soldiers engaged him in conversation, asked if he was Joyce, and when he reached in his pocket for his false passport, the soldiers, believing he was armed, shot him in the buttocks, leaving four wounds. Joyce was charged on the basis that, even though he had misstated his nationality to gain possession of a British passport, until it expired this entitled him to British diplomatic protection in Germany, and therefore he owed allegiance to the King of England at the time he commenced working for the Germans. Joyce was convicted and sentenced to death on September 19, 1945.
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In ufology, the Robert Taylor Incident, a.k.a. Livingston Incident or Dechmont Woods Encounter is the name given to claims of sighting an extraterrestrial spacecraft on Dechmont Law in Livingston, West Lothian, Scotland in 1979 by forester Robert "Bob" Taylor (1919–2007). When Taylor returned home from a trip to Dechmont Law dishevelled, his clothes torn and with grazes to his chin and thighs, he claimed he had encountered a "flying dome" which tried to pull him aboard. Due to his injuries, the police recorded the matter as a common assault and the incident is popularly promoted as the "only example of an alien sighting becoming the subject of a criminal investigation".
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William Cullen Bryant translated The Paradise of Tears by Nikolaus Muller.German Classics 1900 Archive.org :Beside the River of Tears, with branches low, :And bitter leaves, the weeping-willows grow; :The branches stream like the dishevelled hair :Of women in the sadness of despair :On rolls the stream with a perpetual sigh; :The rocks moan wildly as it passes by; :Hyssop and wormwood border all the strand, :And not a flower adorns the dreary land. :Then comes a child, whose face is like the sun, :And dips the gloomy waters as they run, :And waters all the region, and behold :The ground is bright with blossoms manifold.
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He invited a late and dishevelled Rory to eat breakfast with him and a group of his friends, who had adopted the name 'The Breakfast Crew' because it 'wasn't an official club or anything'. Marty appeared once more in that season, albeit briefly. He made several appearances in season five, including an appearance that seemed to be his last. During this, he went to dinner with Rory Gilmore, Logan Huntzberger and a group of Logan's well-to-do friends, some of whom had treated Marty with a lack of respect in the past asking him 'how he could be so big but yet so very small'.
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Railway trackman Tsanko Petrov discovers a large amount of money in bundles on the tracks, but instead of taking the cash for himself he notifies the authorities. The sophisticated head of PR at Bulgaria's Ministry of Transport, Julia Staykova, takes the opportunity to deflect a brewing corruption scandal by holding a ceremony to hail Tsanko as a working-class hero. Unkempt and dishevelled with a debilitating stutter, Tsanko is ridiculed by Julia's PR team while they parade him for the press as a hero. In order for the Minister to present Tsanko with a new digital watch, Julia removes Tsanko's own Slava-brand watch, an heirloom passed down from his father.
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He became well-known locally and was a regular patron of the Shamrock Cafe on Stratford Road and of the Rainbow pub in Digbeth, where he was employed on a casual basis as an odd-jobber and served as an unofficial taxi driver for drinkers. Smith received over 30 criminal convictions for minor offences, beginning in May 1984 when he was fined £100 for theft. His record also included handling stolen goods, burglary and driving without a licence, but no violence. At and weighing 22 stone, with a dishevelled appearance and a soft West Country accent, he was considered gentle by those he met.
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After the battle on the southern side of the Shangani was over, Forbes and his column conducted a cursory search for survivors from Wilson's party, but, unable to cross the river, could see nothing to tell them what had happened. Guessing (correctly) that all Company men beyond the river had been killed, they turned and trekked back to Bulawayo in miserable fashion, their supplies all but gone and the Matabele impeding their progress at every turn. Matabele raiding parties attacked the retreating column six times during its two-week journey back to Bulawayo. In pouring rain, the dishevelled men were soon mostly on foot, existing off horse meat and wearing makeshift shoes made from ammunition wallets.
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The author tells an introductory story of how he sat in a garden in Dijon, and fell into conversation with a dishevelled old man who sat near him leafing through a book.B. Guégan, Gaspard de la Nuit (1925), pp. 3-24. The stranger recognizes him to be a poet, and speaks of how he has spent his life searching for the meaning of Art ('L'art est la science du poète'), and for the elements or principles of Art. The first principle, what was sentiment in Art, was revealed to him by the discovery of some little book inscribed Gott - Liebe ('Dieu et Amour', God and Love): to have loved and to have prayed.
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Though not unsociable per se, he was extremely sensitive and shy. Ball acted as his own mechanic on his aircraft and, as a consequence, was often untidy and dishevelled. His singularity in dress extended to his habit of flying without a helmet and goggles, and he wore his thick black hair longer than regulations generally permitted. While flying a Bristol Scout on 16 May 1916, Ball scored his first aerial victory, driving down a German reconnaissance aircraft. He then switched to Nieuports, bringing down two LVGs on 29 May and a Fokker Eindecker on 1 June. On 25 June he became a balloon buster and an ace by destroying an observation balloon with phosphor bombs.
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Abd al-Rahman ibn Muhammad ibn al-Ash'ath was a descendant of a noble family from the Kinda tribe in the Hadramawt. His grandfather, Ma'dikarib, better known by his nickname "al-Ash'ath" ("He with the dishevelled hair"), was an important chieftain who submitted to Muhammad, but rebelled during the Ridda wars. Defeated, al-Ash'ath was pardoned and married Caliph Abu Bakr's sister. He went on to participate in the crucial battles of the early Muslim conquests, Yarmouk and Qadisiyya, as well as in the Battle of Siffin, where he was instrumental in forcing Ali to abandon his military advantage and submit to arbitration, and later led the Kindaite quarter in Kufa, where he died in 661.
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Villagers are the only act from Ireland to have been signed by Domino Records. Jape's Richie Egan has said of O'Brien: "That gentleman embodies everything I hold dear about music". He spoke of feeling inspired after attending one of their early shows, at a time when he himself had just won the Choice Music Prize. The Irish Times placed them at number six in a list of "The 50 Best Irish Acts Right Now" published in April 2009, commenting: "from what we’ve heard and seen live so far, Villagers generate the type of music (sparse, eerie, casually dishevelled, tangibly cool) that will spread beyond the confines of niche appreciation into a great blue yonder".
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On 28 May 1945, Joyce was captured by British forces at Flensburg, near the German border with Denmark, which was the last capital of the Third Reich. Spotting a dishevelled figure while resting from gathering firewood, intelligence soldiers – including a Jewish German, Geoffrey Perry (born Horst Pinschewer), who had left Germany before the war – engaged him in conversation in French and English. After they asked whether he was Joyce, he reached into his pocket (actually reaching for a false passport); believing he was armed, Geoffrey Perry shot him through the buttocks, resulting in four wounds. Two intelligence officers then drove him to a border post and handed him to British military police.
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The planar cell polarity pathway (PCP) is the most notable β-catenin independent pathway – the Wnt signal is received by the Frizzled receptor, which relays signals to DVL, which then acts as a branch point for two independent pathways, leading to the activation of small GTPases Rho and Rac. For the Rho branch, Wnt signals induce DVL to form a complex with Daam1 (Dishevelled associated activator of morphogenesis 1). This complex then interacts with Rho guanine nucleotide exchange factor WGEF (weak-similarity GEF), which activates downstream effectors like Rho GTPase and Rho-associated kinase (ROCK), which activates actin and cytoskeleton architecture in the cell. For the Rac branch, DVL activates the Rac GTPase.
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Maidman sings lead vocal and plays guitar in SoupSongs, a project devoted to Robert Wyatt's music, put together by Wyatt and Annie Whitehead. Soupsongs have released a critically acclaimed live double album, and performed at London's Royal Festival Hall, Queen Elizabeth Hall, at many other UK venues, and in France, Germany and Italy. Writing in the Guardian, the music critic John Fordham praised the album and said that "Maidman catches the composer's sense of dishevelled dignity and casually poetic radicalism". Maidman also performs regularly with the Orchestra That Fell to Earth (five members of the original Penguin Cafe Orchestra, including Geoffrey Richardson), plays regularly in France with Murray Head, and with Kokomo, Terry Reid and Annie Whitehead.
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Even the maximum restraint cells were requisitioned for temporary use. Throughout the asylum, rooms were crudely adapted to act as operating theatres, radiography departments and pharmacy stations. Contemporary photographs show, however, that the hospital retained some of its pre-war character, and the wards are strewn with large potted plants and ornate furnishings, though little could disguise the hard deal tables, the flagstone floors and the high windows with their cast-iron glazing bars. Stanley Spencer, the painter who served as a medical orderly in 1915–1916, can be glimpsed in one of these photographs – a diminutive, slightly dishevelled figure in an ill-fitting tunic, surrounded by long avenues of beds, each separated by large, ungainly wooden lockers.
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Lady Zhen's hair was dishevelled and she was crying behind her mother-in-law. When Cao Pi asked, Lady Liu told him the woman behind her was Yuan Xi's wife. Cao Pi was so entranced by Lady Zhen's beauty that he married her and treated her well.(世語曰：太祖下鄴，文帝先入袁尚府，有婦人被髮垢靣，垂涕立紹妻劉後，文帝問之，劉荅「是熈妻」，顧擥髮髻，以巾拭面，姿貌絕倫。旣過，劉謂后「不憂死矣」！遂見納，有寵。) Shiyu annotation in Sanguozhi vol. 5.
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Three suggested running away and relocating from the mountain, one suggested to propose a treaty wherein the crows would pay the owls an annual tribute in lieu of safety. The king disliked the counsel of the first four owls. The fifth crow suggested that the crow king rip off some of the advisor's own feathers and attack him, leaving him in a dishevelled state, so that he could infiltrate the owl colony as a double agent. When the owls came upon the crow spy, they didn't know what to do with him, so the owl ruler consulted his advisors, one said to kill him but the other two were in favour of keeping him alive as an advisor.
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My ideal of a clever lady rider is one who can ride far, who can ride at a really useful speed, who mounts hills with comfort, and makes no fuss or show of effort. The stylish, clever lady stops short of being a scorcher, but if women's races were to be organised, the participants would have to run to their limit, or else make a mockery of racing. And that limit is not pleasant to contemplate... the speed woman, dishevelled, grimy and graceless. I believe in a high standard of cycling ability as really worth while attaining by women, but not as racers... Imagine women dressed for speed, on bicycles built for speed, in attitudes necessary for speed, grabbing speed food, taking acidThe meaning isn't clear.
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A dishevelled Sheila returns home after being raped (1986) In 1986, the most notable story line regarding Sheila was broadcast. The story was written in order to keep Sue Johnston on the soap, who had previously expressed an interest in leaving. In 1986, Sheila was raped while walking home from a pub, following her ordeal she bathed, removing any evidence that could have incriminated her attacker. There were three suspects; former friend Matty Nolan, who was furious with her for wrecking his marriage by telling his wife he'd been having an affair; neighbour Pat Hancock (David Easter), who had gotten drunk after a violent argument with this girlfriend and couldn't remember what he'd been up to; and lecturer Alun, who had unsuccessfully tried to initiate an affair.
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The hero (Prithviraj) zooms down and starts whispering to us about Jesus, Frankenstein and Mangalassery Neelakantan, the idol trio who have had a say in his life. With his 'editor-publisher'(Kani) hanging around his arms, the writer that he is, speeds off to Kerala, promising her that he would get traditional attire to cover her up when they reach there. An aged woman (Sukumari) waits around for her bus to arrive in some bus station, while an army officer (Jayasurya) sitting nearby dozes off, his head resting gently on her shoulders. A dishevelled looking man in his fifties (Maniyanpilla Raju), brushes aside the advances of a teenage girl in a shabby looking lodge, as he gets all ready to go somewhere.
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Other central elements that Kahlo derived from Aztec mythology were hybridity and dualism. Many of her paintings depict opposites: life and death, pre-modernity and modernity, Mexican and European, male and female. In addition to Aztec legends, Kahlo frequently depicted two central female figures from Mexican folklore in her paintings: La Llorona and La Malinche as interlinked to the hard situations, the suffering, misfortune or judgement, as being calamitous, wretched or being "de la chingada." For example, when she painted herself following her miscarriage in Detroit in Henry Ford Hospital (1932), she shows herself as weeping, with dishevelled hair and an exposed heart, which are all considered part of the appearance of La Llorona, a woman who murdered her children.
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Sirius, worried, returns to Britain when Harry tells him that his scar has began hurting him again (a signal of Voldemort's presence), and when there were reports of Death Eater activities at the Quidditch World Cup. He sacrifices some of his regained health to help Harry: by the time he reaches Hogsmeade, he is once again gaunt and dishevelled, hiding in a cave with Buckbeak and surviving mainly on rats (with occasional gifts of food from Harry, Ron, and Hermione). He has little influence on Harry in this book; his presence cannot prevent the disaster at the Triwizard Tournament, and he mostly gives Harry advice on how to complete the Triwizard Tasks. He is later summoned to Hogwarts by Dumbledore and listens to Harry's re-telling of Voldemort's rebirth.
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At noon on 22 January the garrison's senior officer, Major Henry Spalding (Chelmsford's quartermaster general), received news of a Zulu presence in the area, and departed from Rorke's Drift in order to ascertain the whereabouts of reinforcements due from Helpmekaar. Consequently, Lieutenant John Chard, a Royal Engineer who had been given the task of maintaining the cable ferry across the river, was left as the senior officer. At around 15:00 a small number of dishevelled horsemen appeared with news that the camp at Isandlwana had been overwhelmed by a Zulu army that was probably on its way to attack Rorke's Drift. Acting Assistant Commissary James Dalton, an experienced former sergeant in the 85th Regiment, persuaded Bromhead and Chard that the best option was to remain at the station rather than make a fighting retreat.
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As Icehouse, the band spent the second half of 1981 touring the UK, Canada and the U.S., whilst Chrysalis released most of their Flowers material under the name Icehouse. The single "Icehouse" was released in Europe and created some interest in the UK, partly because of a video directed by Russell Mulcahy, while in the U.S. the song peaked at No. 28 on the Billboard Top Tracks chart in 1981. "Icehouse" had been written by Davies when he lived at 18 Tryon Road, Lindfield in an old, cold flat of a two-storey mansion – across the street was a dishevelled house which had its lights on all night peopled by short-term residents. Davies later learned it was a half-way house for psychiatric and drug rehab patients.
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During the 1745 Jacobite Rebellion his father sided with the Young Pretender, despite both James and his brother William then holding commissions under George II; James in the army, William in the navy. Remaining loyal to the Hanoverians, James then served at the Battle of Culloden, fighting on the opposite side to his father. During the rout following the Jacobite defeat, the Earl was captured and taken into the government camp, dishevelled and bareheaded, where he was reportedly recognised by James, who placed his own hat upon his father's head. This was the last time they were to meet, as the Earl was then transported to London where he was tried for treason and executed four months later; forfeiting all his lands and titles and thus depriving James of his inheritance.
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In 1999, Thomson was the co- founder, with Billy Childish of the Stuckism art group, which set out to promote figurative painting, in opposition to conceptual art, which they identified with the Turner Prize (whose jury chairman was Sir Nicholas Serota) and the Young British Artists, of which Tracey Emin (who had once been in a relationship with Childish) was a leading representative. Thomson's painting shows Serota, the director of the Tate gallery. He is smiling behind a large pair of red knickers on a washing line, saying "is it a genuine Emin (£10,000)" and thinking, "or a worthless fake?". This is a reference to Tracey Emin's My Bed, literally a display of her (dishevelled) bed with detritus which included a pair of her knickers, shown in the 1999 Turner Prize at Tate Britain.
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Beneath her portrait was a couplet which was frequently repeated in later writings about her: Stendhal, who had attended many of her performances at La Scala, later recalled: > In her, the comic genius flowered in all its glory. Her performances in La > Dama soldato, in Ser Marcantonio and in Il Ciabattino were unforgettable. > Never again shall there be born into the world, solely for the purpose of > ministering to the frivolous pleasures of sophisticated people, another > living being that so shone and sparkled, whose wit was more irrepressible, > nor whose merriment was more irresistible. Gafforini in her artfully dishevelled hairstyle, depicted in Lisbon in 1804 Gafforini continued to sing at La Scala for the 1802 season, appearing in several operas including the world premieres of Mosca's La fortunata combinazione and Fioravanti's La capricciosa pentita.
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The World Owes Me a Living does not appear to have attracted much critical attention on its release. A review from Kine Weekly praised Campbell's performance but found little else of worth, speaking of "ragged, dishevelled continuity" and observing "the gist of the story is timidly revealed in the last reel, but the build-up, with its sketchy romantic interludes, many aimless flights and repeated pub-crawls, is neither good drama nor much of a compliment to the pioneers of British aviation." The British Film Institute did not hold original prints and negatives in the BFI National Archive as of 2010, and classified the film as "missing". The film was included on the BFI's "75 Most Wanted" list of missing British feature films, due mainly to contemporary re-evaluation by film historians of Sewell's output as a director.
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For his drag pieces, the comedian established "The Lady Dresser", a female tailor who was desperate to out-dress her high class customers, and "Daisy Dillwater, the District Nurse" who arrived on stage with a bicycle to share light-hearted scandal and gossip with the audience before hurriedly cycling off.Cotes, pp. 52–53. With Robey's popularity came an eagerness to differentiate himself from his music hall rivals, and so he devised a signature costume when appearing as himself: an oversized black coat fastened from the neck down with large, wooden buttons; black, unkempt, baggy trousers and a partially bald wig with black, whispery strands of unbrushed, dirty-looking hair that poked below a large, dishevelled top-hat. He applied thick white face paint and exaggerated the redness on his cheeks and nose with bright red make-up; his eye line and eyebrows were also enhanced with thick, black greasepaint.
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" Jeanie progressed to regular character status in season 2. As the season came under way, it was revealed that her affair with Benton still continued, unbeknown to her husband, leaving Benton's authoritarian personality "uncomfortably weakened" as the third member of a love triangle. When Jeanie refused to leave her husband, the relationship ended on bad terms, setting up the next chapter in Jeanie's story as she finds employment as a Physician Assistant (PA) at the serial's focal setting of County Hospital's ER. This leads to hostilities from a dishevelled Benton, who proceeds to make her working life a "living hell", until she confronts him. In summary of the plot, Keenleyside noted that "it's nice to see Jeanie being allowed to move beyond the quiet forcefulness that has thus far marked her relationshsip with Peter, and it's even better to see Benton with his tail between his legs for a change.
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When Joseph finally meets his reclusive neighbour he discovers a cold, brooding man lost deep within his own cocoon of silence. He soon realises that in order to truly draw Tom Leyton, he must find the courage to unlock the man’s dark and perhaps dangerous secrets. But Joseph has his own secrets, including the pain of his damaged relationship with his absent father and his childhood fear of the Running Man – a local character whose wild appearance and strange manner of moving everywhere at a frantic pace terrified him when he was a small boy. These dreams suddenly return when Joseph is forced to face his fears and doubts regarding Tom Leyton. As Joseph moves deeper and deeper into his neighbour’s world he confronts not only Tom Leyton’s private hell, but also his own relationship with his father, and ultimately the dishevelled, lurching figure of the Running Man.
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Critical reception to Are You Are Missing Winner was mixed, often focusing unfavourably on the contrast with The Unutterable. Among the album's more negative reviews were that of John Bush of AllMusic, who suggests, "Are You Are Missing Winner represents a rare misstep for the mighty Fall", and Andrew Cowen for The Birmingham Post, who called it "appallingly recorded throwaway kids stuff", and "scrappy even by their standards", going on to write "Mark E Smith sounds paralytic throughout, mumbling and ranting like some sorry old man. You can almost smell the wee." Edwin Pouncey, writing in The Wire, is more upbeat: "…Smith scatterguns half remembered lyrics and conducts a whirlpool of splintered guitar, dishevelled drum and battered bass sounds with a Quasimodic Gene Vincent leather gloved fist that claws even deeper into the raw clay of innovation that birthed rock 'n' roll and continues to fuel Smith's unique vision".
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Soon I was in a virtual car, joyriding through a dystopian landscape with a group of circus clowns. One of them opened a bottle in the front seat and I smelt and felt real-life vodka hit my face; later I was instructed to hold up my left hand, only to see a virtual hand on screen, hairy and stained with blood. My response to the autoteatro-style instructions was as immediate and unquestioning as that of a sleepwalker.' Transmedia aspects of the show included a live performance by a Faruk Clown rock band at the Nightingale Theatre, Brighton; a radio documentary, in which fake anthropologists discussed the Faruk and a fictitious policeman warned people to avoid the show; Faruk clown workshops, in which participants, dressed in dishevelled clothes, were encouraged to 'discover their own inner pariah'; and a fictional parish newsletter given to audience members before the show.
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The celebration proved popular, and when the Queen came of age in 1898, her inauguration was postponed a week to 6 September so as not to interfere with Koninginnedag. The annual holiday fell on the final day of school summer vacation, which made it popular among schoolchildren. It is uncertain how much Wilhelmina enjoyed the festivities; although writer Mike Peek, in a 2011 magazine article about Koninginnedag, suggests she was enthusiastic, there is a story of Wilhelmina, after a tired return from one of these birthday processions, making her doll bow until the toy's hair was dishevelled, and telling it, "Now you shall sit in a carriage and bow until your back aches, and see how much you like being a Queen!" Koninginnedag 1902 not only honoured the Queen's birthday, but was celebrated with increased enthusiasm as it marked her recovery from serious illness.
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The upper cover (not illustrated here, see note for image) is very lavishly studded with large gems, and uses low repoussé relief.Zoomable image from the Morgan Library The composition also centres on a cross, but here a whole Crucifixion scene with a figure of Jesus on the cross and much smaller ones of the Virgin Mary and John the Evangelist. Each of these is in a compartment below the arms of the cross, paired with iconographically unusual female figures; the matching compartments above the arms each contain two angels. Identifications for these lower figures vary; they are described by the Morgan Library as anonymous mourners, "two dishevelled female figures thought to be personifications of Christian souls saluting their Redeemer" as their file note puts itMorgan notes, 3 quoted; Schiller, II, 108 agrees but Peter Lasko, calls them instead "the curiously duplicated figure of St Mary Magdalen (?)"Lasko, 66 To Needham they are Mary Magdalene and Mary Cleophas.
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The Reverend Edmund Farrer in his travels through the church heraldry of Norfolk identifies the arms above, a chevron engrailed, between three pierced mullets, as those of Rugge, and adds the following poetic description of the Mercer's Company's coat of arms: > A demi-virgin couped below the shoulders nebulée, vested and crowned with an > Eastern coronet, and wreathed around the temples with roses (The Mercers > Company, Gules, a demi-virgin couped below the shoulders, issuing from > clouds all proper, vested, or crowned with an Eastern coronet of the last, > her hair dishevelled, and wreathed around the temples with roses of the > second, all within an orle of clouds proper. There is no sign here of the > "orle of clouds," or what on a brass usually takes its place, "a bordure.") There is also a loveknot on the stone in the isle, with the initials R & E. His second wife Alice lies in Plumstead Parva. On a grave-stone, in the church;— > Here lyeth Alice Wayte, first wife to William Hare, Esq.
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Q1 has the direction, "Enter Ofelia playing on a Lute..." The early modern stage in England had an established set of emblematic conventions for the representation of female madness: dishevelled hair worn down, dressed in white, bedecked with wild flowers, Ophelia's state of mind would have been immediately 'readable' to her first audiences.Showalter (1985, 80–81). In Shakespeare's King John (1595/6), the action of act three, scene four turns on the semiotic values of hair worn up or down and disheveled: Constance enters "distracted, with her hair about her ears" (17); "Lady, you utter madness, and not sorrow", Pandolf rebukes her (43), yet she insists that "I am not mad; this hair I tear is mine" (45); she is repeatedly bid to "bind up your hairs"; she obeys, then subsequently unbinds it again, insisting "I will not keep this form upon my head / When there is such disorder in my wit" (101–102). "Colour was a major source of stage symbolism", Andrew Gurr explains, so the contrast between Hamlet's "nighted colour" (1.2.68) and "customary suits of solemn black" (1.2.
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Etty remained a prominent painter of nudes, but from 1832 onwards made conscious efforts to reflect moral lessons. Despite this he continued to be regarded as a pornographer by many, long after his death in 1849; as late as 1882 Vanity Fair was able to comment, "I know only too well how the rough and his female companion behave in front of pictures such as Etty's bather. I have seen the gangs of workmen strolling round, and I know that their artistic interest in studies of the nude is emphatically embarrassing." alt=Dishevelled and distressed naked woman tied to a tree, being cut free by a man in armour Interest in Etty declined after his death as new movements, particularly the Pre-Raphaelites and Aestheticism, came to characterise painting in Britain, and by the end of the 19th century the cost of all his paintings had fallen below their original prices. Very few subsequent artists have been influenced by Etty, and one of the few later works on which Candaules can be considered an influence is The Knight Errant, painted by John Everett Millais in 1870, which depicted the rescue of a distraught woman who has been stripped and tied to a tree.
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