The Institute for Clinical Economic Review — an independent expert body that assesses cost effectiveness of medical treatments — assigned a cost effectiveness value of up to $1,688,000 for Kymriah for its use in children.
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It's made the ritual more appealing because of the cost-effectiveness.
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Products of this type optimize for extreme convenience and cost effectiveness.
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Its high density translates into higher scooter usage, increasing cost-effectiveness.
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We have to take into account cost effectiveness and diagnostic yields.
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It's way far away from working on a cost-effectiveness level.
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But the cost-effectiveness of metformin makes it an attractive option.
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Yet this standard had never been tested for cost-effectiveness, Manchanda explained.
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Companies are also implementing cost-effectiveness initiatives to support their cash flows.
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It will also let the agency consider cost-effectiveness of new medicines.
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European regulators already require companies to demonstrate the cost effectiveness of new therapies.
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It will also let the agency consider the cost-effectiveness of new medicines.
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This group is less focused on cost-effectiveness and more on political feasibility.
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"We can build up our cost-effectiveness and provide high-end service," she says.
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One major factor going for the development of robot nannies is their cost effectiveness.
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For years, researchers working on these programs drummed up mixed findings about cost-effectiveness.
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But aren't regulators bred to the bone to focus on reliability and cost-effectiveness?
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The cost-effectiveness of MA plans also has positive, spill-over effects on traditional Medicare.
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Despite the rebuttal, NICE said it welcomed "further discussions" around the cost-effectiveness of Kymriah.
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They then subject those programs to rigorous evaluations of their implementation, impacts and cost-effectiveness.
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Cost-effectiveness, however, does not appear to be the Trump administration's priority at the moment.
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Title X is an odd target because it is the gold standard of cost-effectiveness.
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In fact, this is also the issue with the lack of our system's cost-effectiveness.
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"That enhances our relative competitiveness and cost-effectiveness when compared to other projects," Cha said.
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COST-BENEFIT ANALYSIS Some drug prices will be evaluated on the basis of their cost-effectiveness.
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Critics include Germany's IQWiG, which plays a key role in determining the cost-effectiveness of drugs.
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And in Japan, regulators are considering a cost-effectiveness test as a means of capping prices.
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As technology continues to mature, the focus is gradually shifting towards finding the most cost effectiveness.
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And digital health companies have to compete with the reliability and cost-effectiveness of traditional care.
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Will there be a cost-effectiveness council, like Britain's National Institute for Health and Care Excellence?
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In many transit advocacy circles, it's considered unfashionable to dwell on these questions of cost-effectiveness.
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"We have not invested much time in explicit estimates of PSPP's cost effectiveness," their review concludes.
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Drone delivery is still in its infancy, so it will take time to determine its cost-effectiveness.
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It's worth noting that drones' cost-effectiveness is also likely to make them equally attractive to pirates.
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That cost-effectiveness is especially appealing in low-income countries, where resources are often scarce for women.
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New ideas on closing the digital divide should be considered, hopefully with an eye toward cost-effectiveness.
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Assuming a 10- to 20-year benefit, the treatment failed to meet cost-effectiveness thresholds, ICER said.
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Frankly, I consider the talk of cost-effectiveness to be not only discriminatory but also pure ableism.
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These recommendations were followed by calls from academics to use cost-effectiveness thresholds to set Medicare policy.
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Economic studies consistently report the cost-effectiveness of early, sustained prevention efforts embedded in public health systems.
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Key to making it all work are three bold-line factors: public safety, cost-effectiveness, and justice.
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Automated smart factories can deploy 6900G connected technology to reduce energy consumption while improving speed and cost-effectiveness.
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Building upon aesthetics and recreation, NUSwan is a comprehensive solution to maximize use of resources and cost effectiveness.
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"Profit was higher because of cost-effectiveness and the rise in sales volumes," Petrol spokesman Sandi Salkic said.
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However, not all of the claims made about their cost-effectiveness and efficacy have stood up to scrutiny.
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In April 2014, NICE initially did not recommend Eli Lilly's lung cancer drug Alimta on cost-effectiveness grounds.
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Balancing social, environmental and economic considerations, agencies draft and OIRA reviews rules, considering cost-effectiveness and possible alternatives.
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Was the request meant to gauge the programs' cost-effectiveness, or was it a prelude to abolishing them?
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Finally, ImpactMatters uses this cost-effectiveness measurement to give each nonprofit a rating of one to five stars.
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"For me, the argument has always been one of cost effectiveness not cost," he told the Thomson Reuters Foundation.
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Additionally, if the performance of the drug slips over time, the drug's cost-effectiveness will be renegotiated, said Pani.
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And much of the inter-office communication gets mired in the dull details of cost effectiveness and software architecture.
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ICER, a not-for-profit group that the pharmaceutical industry loathes, attempts to identify the cost effectiveness of drugs.
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It added that NICE, the UK's drug cost effectiveness agency, had concluded that using Avastin for AMD was safe.
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Because the quality and cost-effectiveness of healthcare in the United States lags behind that in other developed nations.
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That will take time and money, and even then they'll need to evaluate the cost effectiveness of their yields.
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The agency has around 9,000 staff members in more than 150 countries, and it prides itself on cost effectiveness.
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Other ideas — like incorporating cost-effectiveness criteria into Medicare and private plan coverage criteria — are sure to prompt disagreement.
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The search for cost-effectiveness on the part of insurers may indeed be at the heart of the issue.
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But people who have discovered the brand are big fans of the durability and cost-effectiveness of its washing machines.
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Yes. Cost-effectiveness aside, there are also a number of recipes for which powdered Parm is genuinely the best choice.
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Perhaps one of the biggest advantages of the Internet of Things is its efficiency and cost effectiveness of these systems.
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We often hear how these technologies boast capabilities we care about in financial inclusion: efficiency, transparency, security and cost-effectiveness.
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Programs that have demonstrated cost-effectiveness — such as Washington, D.C.'s highly successful school-choice program — are rewarded as well.
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It is the first such annual report by the Boston-based research group, which conducts cost effectiveness assessments of drugs.
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Then we started looking into the cost-effectiveness of different ways in particular to help improve health in poorer countries.
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The size of UK shale reserves remains unknown and the cost effectiveness of extraction has not been studied by the government.
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The draft guidance marks the first time NICE has applied its new cost effectiveness limits for treatments for very rare conditions.
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It's could improve the reliability and cost-effectiveness of orbital spaceflight, but the aircraft's first launch test isn't scheduled until 2019.
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But in truth, there's always been a lot of subjectivity in cost-effectiveness estimates — GiveWell's, as well as any other estimates.
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The QALY is a measure invented to estimate the cost-effectiveness of a medical treatment using mortality, morbidity and cost data.
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That means maximum cost effectiveness, which is good especially with pricier foods like a pomegranate, and it also means tastier juice.
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Instead, they trust an unelected panel of bureaucrats to apply "cost-effectiveness" and "emerging" science to better prepare for severe weather.
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While hydropower may be the right choice in some scenarios, the increasing cost-effectiveness of solar and wind offers viable alternatives.
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NICE is reappraising all the drugs covered by the Cancer Drugs Fund and requiring that they meet tough cost-effectiveness targets.
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NICE data, however, shows only 10 to 15 percent of the drugs it approves currently meet this lower cost-effectiveness hurdle.
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These factors not only determine the cost-effectiveness of the project but also the value of panels to any prospective buyer.
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Equipment at most mines was more than 50 years old, severely undermining efficiency and cost effectiveness of the sector, said Manhando.
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The same is true when it comes to federal agencies: Digitization increases the quality of service, promotes efficiency, and improves cost-effectiveness.
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Ted Cruz spent slightly more than Kasich or Trump per vote but came much closer to their cost-effectiveness than to Rubio's.
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I mean, a fountain the size of the Leaning Tower... that's doable, sure, but its cost effectiveness must be questionable, for real.
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Either scenario is technologically possible, though we would need big breakthroughs in cost-effectiveness of alternative energy for the best-case outcomes.
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Alleging that Southern Company and Mississippi Power had overstated the plant's cost-effectiveness, the Bigger Pie Forum sued to unseal project records.
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Amid war-torn Iraq, the continued, relative stability at Mahmoudiya underscores the cost-effectiveness of helping local people negotiate their own peace.
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In order to get that same cost-effectiveness from Super Mario Party, I would have to play it for over 750 hours.
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The water projects were pure pork, which doesn't often make for good public policy from an environmental, safety, or cost-effectiveness standpoint.
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But this new scheme misses the point and the huge opportunity to truly impact efficiency and cost effectiveness without compromising quality or access.
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The nutrition and obesity researchers I spoke to were also skeptical about the cost-effectiveness and impact of fruit and vegetable incentive programs.
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Anyone skilled in marketing knows the precision, targeting and cost-effectiveness of online strategies to reach buyers, influencers and, in this case, voters.
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And, with an eye on cost-effectiveness, he and President Carter halted the B-1 bomber as a successor to the B-52.
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Specifically, both complaints accuse the company of prioritizing speed and cost effectiveness rather than safety when it comes to its driver-screening process.
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For companies, the issue is cost effectiveness, whether they should spend money on infrastructure or expand the PTC system - especially in the busy northeast.
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The legal industry currently finds itself in need of the innovative solutions for marketing, competition and cost-effectiveness that the legaltech sector can provide.
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While its equipment has been purchased by rural American telcos due to its cost effectiveness, the U.S. is not a critical market for Huawei.
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That's the more likely outcome for a dual-SIM iPhone: it's a matter of convenience for China rather than cost-effectiveness for emerging markets.
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Trump has criticized wind-power, cast doubts on solar power's cost effectiveness, and promised on the campaign trail he would bring back coal jobs.
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Feed the Future, the 6900 USAID-led precursor to the GFSA, has proven the cost-effectiveness and success of such U.S. foreign aid programs.
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A follow-up report will examine the longer-run impacts and cost-effectiveness of program services, including services provided by employment counselors and training.
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Their report, "Measuring Peacebuilding Cost-Effectiveness," showed that for every $85033 we spend on preventing conflict and atrocities we can save $16 in response.
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"Cost-effectiveness modeling can offer additional guidance" on the questions about colorectal cancer screening that "are difficult to answer," he wrote in the editorial.
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It's not entirely clear what accounts for those differences or what the United States can do to increase the cost-effectiveness of its tunneling.
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The institute considers a drug's cost-effectiveness, as well as the type of condition it addresses and whether it's for a particularly vulnerable population.
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The United States has had a historical unwillingness to face cost-effectiveness questions in health care decisions, something many other countries tackle head-on.
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LG said, however, that launch of new flagship devices and greater emphasis on cost-effectiveness will boost profitability for its mobile business this year.
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It is even more astounding when one considers that since 6900 eight different research studies have confirmed the safety and cost-effectiveness of CRNAs.
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Despite the benefits of ecosystems for coastal defenses, we do not work to rebuild and restore them in line with their proven cost-effectiveness.
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What is the relative effectiveness (and cost-effectiveness) of microcredit compared to other potential ways to help extremely poor people, including just giving cash?
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But most fundamentally, all these specific excess costs arise because no part of the political system was focused on cost-effectiveness as a priority.
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Then there's the issue of cost-effectiveness: this level of engineering can be incredibly expensive, especially if work must be done to accommodate said construction.
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But the delivery of useless or low-value services should concern anyone who cares about improving the quality, safety and cost-effectiveness of medical care.
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But the cost-effectiveness of these new technologies hasn't yet been proven, and until if and when it is, that's a huge barrier to uptake.
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The search giant's initiative also has backed Social Finance, a U.S.-based nonprofit that will study the cost effectiveness and success of youth-training programs.
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Buyers want the reliability and beauty of the traditional product but are also keen on the flexibility, cost-effectiveness and modernity provided by electric innovations.
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We're excited to offer this technology to customers as an AWS service – with all of the simplicity, flexibility, reliability, and cost-effectiveness of the cloud.
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The answer is most things on the medical treatment side do not yield a cost-benefit, so what's important is to think about cost effectiveness.
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Currently, Medicare is not permitted to consider cost and the ACA expressly prohibits the use of cost effectiveness in decisions of what to pay for.
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In Britain, routine use is stalled by a funding row, as well as doubts over cost-effectiveness, based on the high price of branded Truvada.
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What's next: Ogilvie says her research team is in the process of doing a cost-effectiveness paper that will be released in about a year.
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This measure would subject major rule making by agencies to dozens of new requirements, with a pervasive mandate for cost-benefit and cost-effectiveness analyses.
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Both have been shown to dramatically lower cholesterol levels, but uptake as been slow as the medical community and health insurers questioned their cost effectiveness.
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First, the department should design and conduct a credible evaluation that can determine the impacts and cost effectiveness of every experiment launched under the authority.
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Blockchain would enable the government to securely collect, store, process, and utilize the massive amounts of information it collects, thereby boosting cost effectiveness and transparency.
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The group has not completed a cost-effectiveness analysis but they calculated that only 10 women would need to be treated to produce an extra pregnancy.
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NICE is also appraising Teva Pharmaceutical Industries' rival biotech drug Cinqaero for severe eosinophilic asthma and has asked Teva to provide more information on cost-effectiveness.
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Japan, confronted with the ballooning cost of caring for an ageing population, is introducing a cost-effectiveness test for drugs as a means of capping prices.
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If you're looking for something a little more in depth, however, you can get the same convenience and cost-effectiveness in an online degree from Coursera.
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European governments control prices in various ways—Britain has the strictest system, refusing to pay for medicines that fail to meet a threshold of cost-effectiveness.
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The reforms expand the Patented Medicine Prices Review Board's (PMPRB) powers, and among other things give it the ability to consider the cost-effectiveness of medications.
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Japan, confronted with the ballooning cost of caring for an aging population, is introducing a cost-effectiveness test for drugs as a means of capping prices.
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They were the same group of experts who in January 2016 urged caution over the vaccine, saying its safety and cost-effectiveness had not been established.
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Never mind that cost-effectiveness only tells a decision-maker to minimize the cost of what may be a wasteful, predetermined and arbitrary action or policy.
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" Bibbins-Domingo pointed out that while cost-effectiveness factored heavily into the results of this study, the USPSTF "does not consider cost when issuing its recommendations.
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A paper published in the Journal of Public Health in 2017 examined the cost effectiveness of all public health guidance issued in Britain through June 2010.
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For example, the most common method for determining incremental cost-effectiveness of health-care interventions is based on a calculation of quality-adjusted-life-years (QALYs).
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And GiveWell is not alone; other groups like the World Health Organization need to make these kinds of calls in their cost-effectiveness research as well.
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When asked about their priorities for purchasing overseas real estate, the respondents said, "high cost-effectiveness" ranked first, followed by investment value and "permanent property rights."
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That cost-effectiveness is unlikely to last long, especially if both players continue to play at stratospheric levels and get offered big contracts at their next signing.
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But the impact on individual drugs, especially the effect of new cost-effectiveness and government budget analyses, will depend on how the PMPRB uses its new powers.
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Wide distribution to a young audience and that cost-effectiveness has proven to be a compelling elixir for investors, who handed the company $30 million in capital.
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"The idea that we base something solely on a cut point determined by one cost effectiveness analysis from ICER is a big step to take," Gellad said.
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NICE, which has taken a firm stance on the issue of the cost-effectiveness of costly new medicines, did not give details of the latest price reduction.
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HR 938 is the type of legislation we need now to enable programs like Medicaid to continue to provide essential benefits while improving cost effectiveness and efficiencies.
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The interaction between gasoline prices, standards and fuel consumption is complicated ("Cost, effectiveness and deployment of fuel economy technologies for light duty vehicles", National Research Council, 2015).
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Providing support The funding will be allocated in portions to be assigned to each enterprise as they reach a set of predefined milestones based on cost effectiveness.
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Put it this way: Could you imagine a company like Apple or Amazon not using their data to continually improve their operations, cost effectiveness and overall results?
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After Garin's announcement, the Formulary Executive Council (FEC) of advisers urged caution over the vaccine because it said its safety and cost-effectiveness had not been established.
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"Many migrant workers continue to believe that the cumbersome process does not outweigh the speed, flexibility and cost-effectiveness of irregular channels," Lim of the IOM said.
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Thankfully, Congress did listen to patients back in 2010, and were concerned enough to ban use of the QALY metric used in cost effectiveness analyses in Medicare.
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But GiveWell has now answered that question pretty thoroughly, with lots of top charities that are all "in a fairly narrow band of cost-effectiveness," Hollander told me.
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Some patient copayments and deductibles, guided by evidence-based approaches such as value-based insurance design, might improve the quality and cost-effectiveness of a single-payer plan.
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This effort will build on 4G in the most efficient way in terms of power, operations, and cost effectiveness, and with the highest level of quality and reliability.
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Insurers are using economic analyses based on a discriminatory cost-effectiveness metric called Quality-Adjusted Life Years (QALY) as negotiating leverage to limit access to life-changing medications.
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While cost-effectiveness had been a near-constant source of praise for the other Sam&aposs Club wines, reviewers were more split than usual on the $19.98 Champagne.
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But it's unclear whether people who pledge really go vegetarian, or how long they stay vegetarian, making it exceptionally difficult to estimate the cost-effectiveness of the video ads.
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All new vehicles would be electric by 2025, due to cost-effectiveness rather than a green revolution, Tony Seba, a serial entrepreneur and author, told a Nomura investment forum.
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"The emergence of more powerful lasers to destroy incoming target may also be worthy of consideration, not least because of the alleged cost-effectiveness of such systems," writes Rudd.
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Tech companies and startups outside of Tier 1 cities may see an advantage in terms of cost-effectiveness and margins when compared with their counterparts in Beijing and Shanghai.
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Last year, NICE opted not to recommend Gazyvaro's broad use in first-line lymphoma, citing, among other things, "concern about the assumptions used in the company's cost-effectiveness modeling".
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"We should be informed fully whether this operation is reasonably done with cost effectiveness and safety and making sure that the best technology is being used," Mr. Suzuki said.
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There, the district's deployment of the tech has ignited a squabble between parents, school board members, state education officials, and privacy advocates over facial recognition's risks and cost-effectiveness.
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The DOJ plans to pause the Legal Orientation Program, which serves over 28500,6900 people a year in 2628 detention centers across the country, while it evaluates its cost-effectiveness.
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Based on a cost-effectiveness threshold of $100,0 per quality-adjusted life year, an exercise intervention could save money as long as expenses are held to just under $3,000.
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"That G3 vehicle will not just have the technical specs for driverless, but it will have a lot of the cost effectiveness necessary to scale built in," Cameron said.
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But if we could see another three or four percent point boost [in turnout], the cost-effectiveness of this tactic will cause it to be much more widely used.
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" It continued, "Aspirin is widely recognized as one of the preeminent antiplatelet therapies of choice across a wide cardiovascular risk continuum, based on its proven efficacy, safety and cost-effectiveness.
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Naturally, pharmaceutical companies and medical device makers wish to protect their profits, regardless of the comparative effectiveness vis a vis other treatments (or cost effectiveness) of what they are selling.
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Here are some more rough GiveWell numbers from its latest cost-effectiveness spreadsheet: The Malaria Consortium, by giving out preventative malaria medications, can save a life for every $2,290 spent.
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The government proposals would change the countries Canada compares its prices to, dropping the United States where they are highest, and set a formula to assess cost-effectiveness of medicines.
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Novartis said feedback and recommendations it gave to ICER were not taken into account, adding the U.S. group did not use the right comparisons to establish cost effectiveness of drug.
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Enterprises that choose hybrid cloud storage are drawn to it because of its scalability and cost-effectiveness, combined with the option of keeping sensitive data out of the public cloud.
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Regeneron and Sanofi shared the Odyssey results with ICER, an independent organization that evaluates clinical and cost effectiveness of new medicines, to seek its view based on the new findings.
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LONDON, May 31 (Reuters) - Britain's cost-effectiveness agency NICE has decided that Merck & Co's immunotherapy drug Keytruda can be used in previously untreated lung cancer patients under special funding arrangements.
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For the last 18 years Britain has led the way in measuring drug cost-effectiveness in a rational and dispassionate way, using a model of economic benefits developed by NICE.
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But as the authors observe, even if their estimate is too optimistic, the intervention would still appear to be in the range of cost-effectiveness that makes it worth pursuing.
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Much as she craved the traditional college experience and the independence that would have come with it, part of her calculation in applying to Hunter had been its cost-effectiveness.
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The Justice Department announced near the end of President Barack Obama's tenure that it would phase out the use of private prisons due to concerns about security and cost effectiveness.
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LONDON, Aug 9 (Reuters) - Britain's cost-effectiveness agency NICE has recommended use of a virus-based melanoma drug from Amgen, reversing an earlier negative decision after the company provided further information.
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LONDON (Reuters) - Pfizer's breast cancer drug Ibrance, or palbociclib, is too expensive to justify its use on Britain's state-run health service, the country's healthcare cost-effectiveness watchdog said on Friday.
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But the long-term advantages of electric trucks could make a lot of sense, both from a relatively obvious ecological perspective, which is obvious, and from the perspective of cost-effectiveness.
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DCP3, the value-for-money report, says that for maximum cost-effectiveness, poor countries would spend about 50% of any increase in funding on primary care and 18% on community care.
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Usmani, the Imperial College consultant, believes proving the cost-effectiveness of a connected device is the key challenge for smart inhalers, along with reassuring patients that their medical records are secure.
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Those advantages of the remote IED – precision, evasion, cost-effectiveness – have prompted authorities increasingly to worry that terrorists will turn next to another device to help them carry out attacks: drones.
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If we turn to "development," we often see that what is sustained in sustainable development is cost-effectiveness and profit-maximization, with the minimum action necessary in terms of environmental responsibility.
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Orthopaedic surgeon Haddad, who has experimented with both, said the machines were very different and healthcare systems would need to assess their cost-effectiveness in the light of clinical trial results.
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Draft rules would change the countries it compares Canadian prices to, dropping the United States where they are highest, and would let the agency consider the cost-effectiveness of new medicines.
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"[LPWAN sensors] are ideal for gathering data about local agricultural and environmental conditions supporting IoT applications designed to increase the quality, quantity, sustainability and cost effectiveness of agricultural production," Yapp says.
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Some of the countries assess the "cost-effectiveness" of drugs and limit how much they will pay for expected gains in the length and quality of life, with some exceptions allowed.
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The researchers applied their model to women with a normal BMI of 18.5 – 24.9 and found similar improvements in outcomes among those who exercise, although the cost-effectiveness thresholds were lower.
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The National Institute for Health and Care Excellence (NICE) cost watchdog said in draft guidance on Monday that Praluent's benefits were uncertain and it was likely to overshoot standard cost-effectiveness thresholds.
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Recently, the Institute for Clinical and Economic Review (ICER), released a scoping document outlining its intentions to evaluate the cost effectiveness of drugs used to treat the autoimmune disease Rheumatoid Arthritis (RA).
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"Ultimately, the market leaders have focused aggressively on improving their cost-effectiveness in their operating models in order to weather the storm as best as possible," Scorpio Managing Partner Sebastian Dovey said.
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Before all people with type 2 diabetes can obtain one, "the major issue will be demonstrating cost effectiveness, through larger clinical trials, given the continual push on health care expenditure," he said.
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For example, New York's Medicaid program used "cost-effectiveness" research to evaluate whether the impact a drug had on a patient's life was worth the price of a new cystic fibrosis treatment.
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In 1992, President George H.W. Bush's Administration established it was an ADA violation for states to employ cost-effectiveness standards in Medicaid out of concern it would discriminate against people with disabilities.
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The National Institute for Health and Care Excellence (NICE), the country's cost-effectiveness agency, said on Thursday the two drugs were being recommended despite uncertainty about how long they extend overall survival.
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" Without addressing the CVS plan directly, the group said that "blunt cost-effectiveness thresholds ignore what individual patient and providers value and conflict with the movement toward personalized, 21st century health care.
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When I'm deciding what to do with that money, I turn on that bright light of cost-effectiveness and try to make as much progress as I can on the world's problems.
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"Cost-effectiveness analyses support a qualified recommendation to adopt an earlier starting age for screening only if the screening rate in persons aged 50 to 75 years is already high," Pignone wrote.
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Using data from randomized trials, researchers calculated that using the new vaccine would save money over the long term, based on statistical measures that quantify the cost effectiveness of health care measures.
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Indeed, the federal Office of Management and Budget has consistently given its top cost-effectiveness rating to the Environmental Protection Agency, with benefits typically exceeding costs by a 10 to 1 ratio.
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Results like those land New York in the No. 3 spot in the list of most fun cities despite its poor ranking — dead last, at 182 out of 182— for cost-effectiveness.
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Other factors included cost-effectiveness, teaching children something, imparting them with cultural experiences, and giving them something to show or talk about with all their friends when they finally get back to school.
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The Boston-based Institute for Clinical and Economic Review (ICER) made the determination using a commonly cited cost-effectiveness threshold that values each "quality-adjusted life year" (QALY) gained at $100,000 to $265,2000.
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Crucially, Thailand's Health Intervention and Technology Assessment Programme, a quasi-governmental body, analyses the cost-effectiveness of treatments, as well as ensuring that cancer cases such as Ms Waree's are dealt with sympathetically.
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RA affects more than 1.3 million Americans, and it is one of many diseases that ICER is reviewing to determine the cost effectiveness of the drugs that doctors use to treat these conditions.
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Twenty years from now, 50 years, 100, do you think anyone will care about the elegance or cost-effectiveness of the transition from coal to solar power, or from diesel to electric buses?
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Lenvima is not included in the government's re-launched Cancer Drugs Fund (CDF) and, as a result, it will have to wait its turn to be assessed by the cost-effectiveness watchdog NICE.
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Why it matters: Getting out of the gate first and pricing below independent cost-effectiveness estimates may give the pharmaceutical giants the upper hand even once the other migraine drugs hit the market.
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ICER said it concluded that Adakveo's annual cost should be $25,410, down from an estimated $88,000 bill, and that Oxbryta must be trimmed to $1003,218 from about $84,000, to meet cost-effectiveness thresholds.
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And because cost-effectiveness models systematically disadvantage the most complex patients, these communities have a long history opposing the use of QALYs as the benchmark to measure the value of health care interventions.
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While some applauded the F.A.A. for finally creating a system to rapidly identify owners of rogue — potentially deadly — drones, others declared that this was going to drastically hinder drone efficiency and cost effectiveness.
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While some applauded the F.A.A. for finally creating a system to rapidly identify owners of rogue — potentially deadly — drones, others declared that this was going to drastically hinder drone efficiency and cost effectiveness.
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Britain's healthcare cost-effectiveness agency NICE, which decides if medicines should be used on the state health service, has decided Roche's immunotherapy drug Tecentriq is worth using to treat certain patients with bladder cancer.
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Novartis leaders said Friday that the price met their targets of cost-effectiveness, with the newly approved treatment costing about half of what another treatment for the disorder, Spinraza, might cost over 10 years.
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Earlier this year, a non-profit U.S. cost-effectiveness watchdog, the Boston-based Institute for Clinical and Economic Review (ICER), labeled Luxturna too expensive and suggested steep discounts to make it worth their while.
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"Based on the available scientific evidence presented to the Council, there is still a need to establish long-term safety, effectiveness and cost-effectiveness," the FEC told Garin in a letter on that day.
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Its basic cost-effectiveness threshold is up to 30,000 pounds per QALY and in future it wants to incentivize drugmakers to come in below 10,000 pounds by offering rapid approval for "exceptional value" products.
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"These cost estimates suggest that the UDN approach has the potential to cut short an expensive medical diagnostic odyssey, and they are consistent with recent cost-effectiveness analyses for genome sequencing," the paper says.
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Here are some of the main factors that may affect Swiss stocks: Novartis' gene therapy for blindness, Luxturna, is recommended for use on England's public health service, the country's healthcare cost-effectiveness watchdog said.
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They calculate that this could save lives for about $60 per year of life saved, and point out that even if they're wrong by a factor of five, that'd still be impressive cost-effectiveness.
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As MedPAC considers whether cost-effectiveness has a place in Medicare payment policy, there is good reason to be concerned about the implications of health-care coverage policy built on population-based value assessments.
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In a 2018 report, the Institute for Clinical and Economic Review, which evaluates the cost-effectiveness of drugs, found that the cystic fibrosis drugs the company sells should cost as much as 77 percent less.
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However, faster adoption may be at hand thanks to a new rule being proposed by the Department of Labor (DOL), which will demand a powerful technology-driven platform geared toward cost-effectiveness and compliance adherence.
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"Although our primary focus is the 100% satisfaction of our customers, we also need to take into account the cost effectiveness of continuing to do business on an individual basis," the email read in part.
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Medical guidelines from the National Institute of Care and Excellence (NICE) also stress the relative cost effectiveness of LARC (such as the IUD) when compared to the pill, and recommend that uptake should be increased.
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"While a range of QALY thresholds were used, we believe cost-effectiveness assessments in SMA should be compared to currently available, chronic therapy and be assessed at the ultra-rare disease QALY threshold," he said.
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Deliberating before the vote, the committee examined the cost-effectiveness of the two vaccines by estimating the total price of each vaccine and the costs when people become ill and compared the relative economic impacts.
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A cost-effectiveness analysis published in 2014 replicated the findings of others that came before it: A dollar invested in syringe exchange programs saves at least six dollars in avoided costs associated with H.I.V. alone.
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The National Institute for Health and Care Excellence (NICE), which determines the cost-effectiveness of new drugs, and NHS England say their new procedures will fast-track the availability of drugs that offer exceptional value.
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The projects to be funded will be selected based mainly on the degree of innovation of their selected technology and also their feasibility, the amount of energy produced, cost-effectiveness, and other impacts, it said.
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At a recent public meeting, the Medicare Payment Advisory Commission (MedPAC) appeared eager to pursue an "aggressive" approach that would encourage Medicare to rely on cost-effectiveness analysis to make Medicare coverage and reimbursement decisions.
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Why you should consider donating: Because it's so new, the Climate Emergency Fund definitely has less of an evidence base than the organizations listed above, so we'll have to monitor its impact and cost-effectiveness.
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The new regulations expand the information the PMPRB can consider when setting drug price caps, among other things, giving it the ability to consider cost-effectiveness, measured in quality-adjusted life years, for the first time.
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But on Friday, ICER said that based on Novartis' additional clinical data, the broad FDA label and its launch price, it believed that the drug fell within the upper bound of its range for cost-effectiveness.
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The new Praluent pricing would be tied to an independent review conducted by an organization that evaluates clinical and cost effectiveness of new medicines and be based on Praluent data unveiled on Saturday, the companies said.
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The lower investment sum, apart from the better cost effectiveness per dollar spent, also resulted from a slowdown in China, Japan and other emerging markets, mainly due to slower than expected growth in demand for power.
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"Despite the current, turbulent digital ecosphere, it is clear that marketers are attracted to the cost-effectiveness of digital advertising and its ability to reach and accurately target their consumers," said IPA's director general Paul Bainsfair.
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Russia to date has been the primary perpetrator in waging campaigns aimed at specifically undermining democracies, we can expect other nations to have been inspired by the cost effectiveness and perceived success of the Kremlin playbook.
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This pharmaceutical benefit has created a highly regarded system for evaluating prescription drugs: An independent advisory board of doctors, academics, and patient advocates makes recommendations to the government about covering drugs, based on their cost-effectiveness.
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In today's big stories, Alphabet is investing in health insurance startup Oscar, CVS is targeting the cost-effectiveness of new drug launches, and we finally have a date for oral arguments in Texas's lawsuit against ObamaCare.
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According to Founders Pledge's cost-effectiveness model from 2018, a donation of just 303 cents to the Coalition for Rainforest Nations will avert approximately a metric ton of CO2 (or the equivalent in other greenhouse gases).
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He also will have to battle Pentagon bureaucracy to achieve the efficiency and cost-effectiveness he has pledged to deliver and battle Congress to get the funds needed to make the investment he desires in the military.
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LONDON (Reuters) - Cheaper "biosimilar" copies of expensive biotech drugs received a boost in Britain on Tuesday when the country's health cost-effectiveness agency NICE said patients needing such medicines "should be started with the least expensive drug".
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LONDON (Reuters) - Britain's healthcare cost-effectiveness agency NICE has decided Roche's new immunotherapy drug Tecentriq is too expensive to justify its routine use to treat bladder cancer, but still hopes it can be used in certain circumstances.
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The new features of the regulations, which take into account cost-effectiveness of medicines and their impact on government budgets, apply only to drugs approved by Health Canada after the rules are officially published later this month.
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The key is that Superfund remediation is not an exact science, which is why experienced senior managers are needed to deal with such disparate Superfund items as waste toxicity issues, cleanup cost-effectiveness and community reaction matters.
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Implementation and cost effectiveness are two fields that we must invest in heavily if we are to curb the rising costs of medical care (a would-be benefit of a single payer system), and decrease overdose deaths.
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Since the vaccine - known as RTS,S or Mosquirix - is only partially effective and needs to be given in a four dose schedule outside normal childhood vaccination plans, experts have questioned its potential usefulness and cost effectiveness.
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There's a glut of environmental organizations out there and a lack of rigorous research on their impacts and cost-effectiveness, though that'll hopefully change soon with the arrival of brand-new evaluators like Giving Green and ImpactMatters.
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Considering the value this treatment offers across the four key measures, we set the Kymriah list price for pediatric use at $475,000, well below the cost effectiveness value set by ICER — and $373,000 for rapidly progressing adult cancers.
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A Regeneron representative told CNN that it and Sanofi met payers, pharmacies and the Institute for Clinical and Economic Review -- a nonprofit organization that analyzes the cost-effectiveness of medical treatments -- before determining the list price of Dupixent.
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If we could maintain that level of cost-effectiveness at billions of time the load, which we probably can't, as these plants have energy costs of their own, that'd mean removing 100 gigatons would cost us $9.4 trillion.
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Pricing it near the level of another recent MS drug entry, Roche's Ocrevus that lists at about $65,000 annually, would put the Novartis medicine "well above commonly cited thresholds for cost effectiveness," ICER said in a draft report.
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"Flu medicines, for example, can be seen to have very low cost-effectiveness because they don't save people's lives, except those of infants or pregnant women, compared with cancer drugs that are critical for some patients," he said.
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" In a statement to The Hill, the drug lobbying group Pharmaceutical Research and Manufacturers of America said it opposes "the misuse of subjective, one-size-fits-all cost effectiveness thresholds to deny patient access to life saving medicines.
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For the last 18 years Britain has led the way in measuring drug cost-effectiveness in a rational and dispassionate way, using a model of economic benefits developed by the National Institute for Health and Care Excellence (NICE).
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The Department of Justice has temporarily ended the Vera Institute's Legal Orientation Program and immigrant "help desk" in order to investigate the program's cost-effectiveness, the Washington Post's Maria Sacchetti reported and has since been confirmed by Axios.
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As Novartis prepares to launch AVXS-113, it also hopes for tacit endorsement of its pricing strategy from the non-profit Institute for Clinical and Economic Review (ICER), which is currently reviewing the cost-effectiveness of SMA therapies.
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It was set up by the Affordable Care Act to test how different medical treatments stack up against one another — but PhRMA insisted that PCORI would not be able to take cost effectiveness into account — and it doesn't.
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Commissioners acknowledged the political hurdles and previous resistance to implementing cost-effectiveness in Medicare when proposed and rescinded back in 1989 and 2000, but did not take much time to discuss the concerns that led to such opposition.
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It is troubling to me that the "incremental approach" suggested by commissioners may be intended to impose cost effectiveness over time, thereby avoiding intense scrutiny despite its methodological flaws and long-term impact on patient access to care.
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LONDON (Reuters) - A new leukaemia drug viewed by industry experts as a future blockbuster has been rejected by Britain's healthcare cost-effectiveness agency NICE, which said it could not be confident the medicine represented an effective use of resources.
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"In view of the long interval between infection with HPV and development of disease, [the Joint Committee on Vaccination and Immunisation] are supportive of changing the methods for calculating cost effectiveness to consider HPV vaccine for boys," she said.
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After hearing MedPAC's plans for future recommendations, I hope that Congress and the administration will step in to ensure that the existing statute protecting patients from denied access to care based on flawed cost-effectiveness analyses is not circumvented.
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That's partly because there's a large body of research on the benefits of cash transfers, GiveDirectly's preliminary evaluation was very promising, and GiveWell has found that cash rivals the best health programs as far as cost-effectiveness is concerned.
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"We believe this move will provide us with greater cost-effectiveness and access to Nasdaq's unique portfolio of tools and services to connect with our investors more efficiently," Jamie Caulfield, Pepsi's senior vice president of investor relations, said in a statement.
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"FAA's disappointing reform outcomes are largely the result of the agency's failure to take full advantage of its authorities when implementing new personnel systems and not using business-like practices to improve its operational efficiency and cost effectiveness," the report said.
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Beyond the price tag "The problem is cost-effectiveness, and that is why the government hadn't made a decision to vaccinate boys in this country," said Jo Morrison, co-ordinating editor for the Cochrane Gynae, Neuro and Orphan Cancer Group.
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Having children get recommended vaccines, counseling to discourage young people from starting to use tobacco, and counseling adults to stop using tobacco achieved the highest possible life-extending and cost-effectiveness scores, the panel reported in Annals of Family Medicine.
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ZURICH/BERLIN, Sept 4 (Reuters) - Here are some of the main factors that may affect Swiss stocks on Wednesday: Novartis' gene therapy for blindness, Luxturna, is recommended for use on England's public health service, the country's healthcare cost-effectiveness watchdog said.
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Aside from valuing the usefulness and cost-effectiveness of the service, some Uber users fear that Transport for London's decision suggests that London isn't as open for business as it likes to appear, especially with the so-called Brexit looming.
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In 22018, the British government set up the National Institute for Care Excellence, or NICE, to assess the cost-effectiveness of medications, procedures, and other treatments, and make recommendations to the National Health Service about what to cover and how.
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First, the key is to recognize that Superfund remediation is not an exact science, which is why experienced senior managers are needed to oversee such Superfund remedy issues as hazardous waste management, cost-effectiveness, and community and state interactions with EPA.
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In Britain, the National Institute for Health and Care Excellence (NICE), the cost-effectiveness watchdog, recommended the new drugs for the majority of hepatitis C patients, but the British Medical Journal said NHS England had defied NICE's authority by rationing access.
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Still, not everyone is completely on-board with the idea, with some people questioning the cost-effectiveness, whether the detachable cabin would compromise the structural integrity of the rest of the plane, and what happens to the pilots after the cabin detaches.
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The technology startups that are well-positioned to build lean and effective solutions for the entire industry are those that focus on solving specific pain points including improving, visibility across the logistics chain; speed of delivery; and cost effectiveness of storage and fulfillment.
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Though we encourage you to still think about the cost effectiveness of the brands you're buying from, for a deal that's thrifty, H&M may be the best stop for testing out a swimsuit trend in your size without having buyer's remorse.
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When Britain's National Health Service tested the cost-effectiveness of remote support for patients with chronic obstructive pulmonary disease, it found that an electronic tablet paired with sensors measuring vital signs could result in better care and enormous savings, by enabling early intervention.
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Another approach: The Institute for Clinical and Economic Review (ICER) recommends prices based on drugs' clinical effectiveness relative to alternative treatments (and the strength of evidence for it), cost-effectiveness, and the extent to which prices are sustainable with health care program budgets.
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In short, the standard recipe for legislation is unlikely to produce the type of insights that can best help federal agencies or Congress continually improve their results and cost effectiveness, meaning fewer lives improved and less bang for the buck for taxpayers.
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Julia Wise, who works in the EA community, recently wrote a blog post explaining that although cost-effectiveness analysis is a useful tool that she wishes more people applied to more problems, it's not meant to govern every single decision you make.
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The launch was a product of multiple factors: the desire for increased cloud-based products inside government, the push to improve the cost-effectiveness and flexibility of the government's $80 billion IT spend, and the need for greater sustainability and transparency of IT infrastructure.
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In an effort to stay within the bounds of state limitations on what the city can and can't regulate, Seattle's ordinance says that driver unionization is needed to ensure the "safety, reliability, cost-effectiveness, and the economic viability and stability" of ridesharing and taxi services.
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Dr. Steven D. Pearson, the president of the Institute for Clinical and Economic Review, which evaluates the cost-effectiveness of drugs, said the problem is that in the United States, drug companies control the prices, especially in the case of newly approved drugs like Orkambi.
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While the cost-effectiveness of regular screening programs for vision and hearing in older adults has yet to be demonstrated, experts strongly recommend periodic exams to pick up correctable problems that may diminish the risk of dementia and would certainly improve quality of life.
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The researchers evaluated studies for methodological quality, then gauged how AA and 212-step treatment fared in terms of rates of continuous abstinence from alcohol, percentage of days abstinent, longest period of abstinence, drinking intensity, alcohol addiction severity, alcohol-related consequences, and cost-effectiveness.
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Dr. Steven D. Pearson, the president of the Institute for Clinical and Economic Review, which evaluates the cost-effectiveness of drugs, said the problem is that in the United States, drug companies control the prices, especially in the case of newly approved drugs like Orkambi.
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Other countries, including the UK, may require a favorable cost effectiveness ratio before a treatment is placed on the national formulary — meaning that some treatments, such as some cancer drugs, won't be recommended for routine funding if they are too expensive relative to their clinical benefits.
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"The synergies achieved through the merger will benefit the clients of both companies ... Furthermore, thanks to the merger, the cost-effectiveness of the entire earnings-related pension insurance system will improve significantly and the sector's solvency will strengthen overall," Ilmarinen chairman Mikko Helander said in a statement.
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A new device launching on Indiegogo Monday could bring some better balance to the cost/effectiveness equation – the Insta360 Air is a clip-on 360-degree video camera with livestreaming capabilities that will cost $3603 in pre-order, or $119 when it's available post-crowdfunding campaign.
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Under the new rules, Canada will change the countries the federal drug price regulator, the Patented Medicine Prices Review Board (PMPRB), compares domestic prices to, dropping the United States and Switzerland where prices are highest, and let the agency consider the cost-effectiveness of new medicines.
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She said while the new features of the regulations, which would take into account cost-effectiveness of medicines and their impact on government budgets, would only apply to new drugs, changes to the countries Canada compares its prices with could affect some drugs already on the market.
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"Data on the safety, efficacy, cost-effectiveness, and emotional risks of elective oocyte cryopreservation are insufficient to recommend elective oocyte cryopreservation," the organization concludes in its Mature Oocyte Cryopreservation guidelines, citing relatively low success rates and the idea that it could inspire "false hope" in patients.
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Charles King, principal analyst at Pund-IT sees several drivers from simplifying the availability of and access to cloud-based applications to easing the adoption of hybrid cloud workloads, but perhaps most important is a limit to the cost-effectiveness of an entirely public cloud strategy.
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Though you may make some sacrifices in the user-interface department — it's a bit clunky and not as intuitive as some of the more expensive services — the streaming quality is top-notch, making its cost-effectiveness a no-brainer if Sling carries the channels you watch.
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According to letters that ISS sent cleaners, the redundancies are being done in the name of "cost effectiveness" and in agreement with EY. IWGB argues that such redundancies will place additional strains on an already taxed workforce, which includes many migrants who depend on low-wage work.
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"The momentum really hasn't slowed, and we are likely to see states continuing to push, to look for ways to help manage drug costs," said Dr. Steven D. Pearson, the president of the Institute for Clinical and Economic Review, which evaluates the cost effectiveness of drugs.
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While cost-effectiveness models that rely on QALYs have a basic appeal for making population-level decisions, in 1992 the Secretary of the U.S. Department of Health and Human Services (HHS) publicly recognized their discriminatory impact for people with disabilities when used to determine access to care.
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But if most of the benefits of Head Start come from the intangible skills it teaches, we should work on learning how to measure them, so we don't have to squint at longitudinal studies to identify the effects and estimate the cost-effectiveness of the programs.
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Housing experts and board members at the San Juan Community HomeTrust said that beyond cost effectiveness, another appeal of the project was more subtle, but no less crucial: The trust's financial donors have responded well to the idea that old houses of character are being rescued, along with local families.
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These findings are significant because coastal risk managers, insurers, engineers and policy makers at all levels can now directly compare the cost effectiveness of nature-based ("green") and structural ("gray") defenses for reducing risk from storms and sea level rise across a region as large as the Gulf of Mexico.
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Recovery After an Initial Schizophrenia Episode (RAISE)-Early Treatment Program (ETP) demonstrated that patients who were receiving CSC were staying in school, had better interpersonal relations, an improved ability to hold a job, better quality of life, high rates of recovery and overall much greater cost-effectiveness than typical treatment.
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The new features of the government's proposed regulations, which would take into account cost-effectiveness of medicines and their likely impact on government budgets, would be limited to new drugs, Health Canada told Innovative Medicines Canada (IMC) and BIOTECanada, the patented drug industry's main lobby groups, in a letter dated April 8, 2019.
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LONDON (Reuters) - Britain's healthcare watchdog NICE, which assesses the cost-effectiveness of medical treatments, has stopped short of recommending the use by the National Health Service (NHS) of Merck & Co Inc's immunotherapy drug Keytruda in newly diagnosed lung cancer patients, after giving the go-ahead in December for patients who had prior treatment.
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Why it matters: The Trump administration is making cost-effectiveness a major theme this year, but it's sure to be accused of undermining ACA enrollment, given all of the Trump administration's battles to repeal the law — and given that it also cancelled advertising for the final days of last year's open enrollment.
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The new CDF provides managed access to new cancer medicines for a limited time if the clinical and cost effectiveness of the drug is still not certain enough for it to be approved by the National Institute for Health and Care Excellence (NICE), which agrees which medicines can be funded via the NHS.
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The causal inference behind Impact Matters' estimates is also necessarily limited; they can't run whole experiments to evaluate the cost-effectiveness of every single charity, so instead they build detailed models to try to approximate an estimate of each charity's impact (here's their methodology for emergency shelters for people experiencing homelessness, for instance).
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A proposal from the Hamilton Project would give the Centers for Medicare and Medicaid Services (CMS) more resources to scrutinize medical technologies and allow the agency to experiment with "reference pricing": Medicare would pay a single price for all treatments, for a given condition, that have similar therapeutic effects, up to a cost-effectiveness threshold.
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Others, like the dirtied corpse of an unclaimed homeless man, haunt you because of the lack of personal items that you don't need to remove before cremation (a method of disposal used for cost effectiveness.) You end the daily ritual by attending each service, talking to the bereaved, and bowing your head over their deceased.
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Thus, each thousand-page codebook from the various federal, state, city, township and independent agencies – all dictating interconnecting, location and structure-dependent needs – lead to an incredibly expansive decision tree that requires an endless set of simulations to fully understand all the options you have to reach compliance, and their respective cost-effectiveness and efficiency.
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In a preliminary analysis of cost-effectiveness, I.C.E.R. concluded that if the Amgen drug cost $8,500 a year, the price would be reasonable for the expected improvement in quality of life for patients with a migraine at least 15 times a month and no other options, said Dr. David Rind, the institute's chief medical officer.
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What's needed is for "policy makers at the local, state and federal level who are considering the cost effectiveness of infrastructure expansions to consider that you're not just letting people get on social media in their spare time, you could also be allowing people to access telemedicine who might otherwise not be able to," Drake said.
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When you've looked at these questions enough, it starts to feel unprincipled to say that certain kinds of subjective judgments are welcome in our cost-effectiveness estimates (in fact, impossible to avoid), but other kinds of subjective judgments — say, how much of the credit for this law passing is it reasonable to assign to this charity?
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During the 2009 discussions and debates over the Affordable Care Act (ACA), I served as the chair of the House GOP Doctors Caucus, leveraging my more than 25 years as a practicing OB-GYN, and one key issue of significant concern for our group was the promotion and utilization of cost-effectiveness data and comparative effectiveness research (CER).
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Like his brother-in-law, Paul Samuelson (whom he once compared to Humphrey Chimpden Earwicker, the protagonist of James Joyce's "Finnegan's Wake"), he popped up in different places and guises, offering insights into prediction markets, learning-by-doing, antimalarial drugs, discrimination between the races, equality between the generations, petrol-price controls, arms reduction, advertising, public investment, the "carrying capacity" of the Earth and the cost-effectiveness of airframes.
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