Both his Twitter and Instagram pages appear to be inactive.
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Phone contacts for Bravo and Cubillos were also found to be inactive.
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Ironically, cultofrazer appears to either be inactive, or has itself been hacked.
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Starting on Monday, Congress will be inactive for two weeks until mid-April.
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In fairness to people, we have made it so easy to be inactive.
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If form holds, McFadden will be inactive again with Elliott getting a late reprieve.
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The House was expected to be inactive on Friday and all of next week.
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This flexibility, and ceding of some control, doesn't mean that students should be inactive.
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An important piece of infrastructure for two major strains of malware appears to be inactive.
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An important piece of infrastructure for two major strains of malware appears to be inactive.
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An important piece of infrastructure for two major strains of malware appears to be inactive.
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In these two great apes there were two NOTCH2NL genes, but they seemed to be inactive.
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Fuller did not practice on Saturday, fueling speculation that he would be inactive for the first time.
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Rookie Dwayne Haskins will serve as the backup, and Week 1 starter Colt McCoy likely will be inactive.
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Even more worrisome, says Salmon, is a trend toward a laxer standard for judging an account to be inactive.
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INSIDE PITCH AARON HICKS has inflammation in his left shoulder and will be inactive for four to five days.
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Older people are more likely to be inactive as a result of back pain, for example, the authors point out.
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McInnes' page appears to be inactive, but a search for "Proud Boys" on Facebook still unearths a handful of regional pages.
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Being willing to be inactive or less active means you'll be available when something truly worthy of your best effort comes along.
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Twitter said in a blog post in early July that weeding out accounts would not hurt metrics because the accounts would mostly be inactive.
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Baylor St. Luke&aposs Medical Center said Friday that the transplant program will be inactive for 14 days as administrators assess what&aposs gone awry.
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When Earnest shared his letter to 8chan, he also included a link to a possible Facebook live stream (though the link proved to be inactive).
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Yet while Hunt is not the forward moving striker that Overeem was, Lesnar cannot simply be inactive for a few minutes and then hope to shoot.
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Children whose parents are sedentary often tend to be inactive themselves, whereas parents who are physically active typically have children who move around and exercise often.
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The group, which had been thought to be inactive, claimed responsibility for an April 2014 bomb that was placed in a parked car in central Athens.
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A Hong Kong High Court judge in the BDA case described Jiushun and three other companies as appearing to be inactive corporate vehicles controlled by Chinese citizens.
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Mysteriously, Eagles head coach Doug Pederson then promoted No. 2 overall pick Carson Wentz from a likely-to-be-inactive third-stringer to the Week 1 starter.
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As every Broaden patient was told beforehand, one in three of them would start the trial with a device that would be inactive for the first six months.
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He was 56 when he left the presidency, and I remember after the re-election loss he was planning his next stop and he wasn't going to be inactive.
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The Bureau of Alcohol, Tobacco, Firearms and Explosives and ICE have announced their accounts will be inactive, but the TSA and State Department are still active as of Monday.
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"The virus can be inactive for a long period of time but you can still be shedding the virus around the mouth and spread it to other people," Green says.
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I think that we tend to conceptualize victimhood as a one-dimensional, pretty passive thing, like to be a victim is to be inactive or to be just unilaterally helpless.
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His critics have seized on comments that he "sacrificed" moving to a wealthy neighborhood in Washington and a CNN reportthat found the former senator's voting status to be "inactive" in Indiana.
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The company said it is reaching out to "many accounts" that don't meet its requirements, but declined to share a timeline or an estimate of the number it considers to be inactive.
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He then mails letters to those individuals' addresses that explain how his group has determined they may be inactive and urges them to re-register or face possible challenges to their voting status.
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While many of these subscription features could be inactive when a customer finds a three or four-year-old BMW on the market, it makes it easier for that person to get the features they want.
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A study done in geriatric homes found that the people who say some version of "Time is speeding by" tended to be more active and happier, whereas those who said time was moving slowly tended to be inactive and depressed.
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People who spent more time in front of the television were more likely to be inactive, overweight, smokers, heavy drinkers, unhealthy eaters and to have an annual household income below $50,000, researchers report in the Journal of the American Heart Association.
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The Racoș volcano is the oldest volcano in the region, and appears to be inactive.
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The following events appear to be inactive or have no reference that show them to be active.
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A thyroid adenoma is a benign tumor of the thyroid gland, that may be inactive or active (functioning autonomously) as a toxic adenoma.
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The dimer (a substituted tetraaminoethylene) was believed to be inactive to the electrophiles (E-X), and thought to merely act as a stable carbene reservoir.
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All three addresses would be inactive. It could be used in a loop to wait for the operator to take some action before perhaps reminding him.
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Some on-line spreadsheets provide remote data update, allowing data values to be extracted from other users' spreadsheets even though they may be inactive at the time.
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Four of the DH domains are predicted to be inactive based on a point mutation found in the active site sequence. Figure 1. Domain Organization of Mycolactone.
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TX Transfer from address A to address C. Address B MUST be Inactive (see Modes of Addressing) TS Transfer from address A to address B then JUMP out of sequence to the command at address C. C must be a direct address. Optionally A and B can be Inactive and the command becomes a pure jump. This is the nearest that this machine gets to a GOTO command. MT Transfer from address A to address C several times.
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Later the society was renamed the American Plant Life Society, and its yearbook was called Plant Life. Amaryllis Year Book. In 1984 Plant Life became Herbertia again. As of 2016 the Society appears to be inactive.
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The dam's reservoir will have a capacity of , of which will be active (or live, useful) storage and will be inactive (dead) storage. At a normal elevation of above sea level, the reservoir surface area will cover .
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The related compound 7-MeO-MiPT (cf. 5-MeO-MiPT) was also found to be inactive, suggesting that the 7-position has poor tolerance for bulky groups at this position, at least if agonist activity is desired.
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The title alludes to the Jewish belief of "waiting for the Messiah"; in this case, characters are shown at first to be inactive and dormant, until death and crisis forces them to take action and reevaluate their lives.
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The original project appears to be inactive, while a currently maintained version exists and is packaged in various GNU/Linux distributions such as Debian and Fedora. This version is available from the repository of Debian developer Tatsuya Kinoshita.
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It is also reduced, hydrolyzed and glucuronidized by unspecified enzymes. All metabolites seem to be inactive. Biological half-life is estimated to be 37 hours. 29–51% are excreted via the urine and 44–77% via the faeces.
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Throughout the first half of September, hotspots continued to smolder within the Ferguson Fire's perimeter. On September 19, 2018, InciWeb declared the Ferguson Fire to be inactive, after a lack of fire activity was detected within the containment lines.
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On January 31, 2020, the website's staff released a statement declaring TV By The Numbers to be inactive starting February 1, 2020. The staff bid goodbye and thanked readers. As of August 2020, its URL redirects to Zap2It's TV listings service.
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And also, numbers which don't receive calls within 30 days are taken to be inactive and removed from the service. Direct customer support is not provided. The free plan does not support outgoing calls, except to toll-free telephone numbers.
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The authors theorize that this may be due to the actors actively suppressing their own sense of self in order to portray another character. Similarly, the dmPFC has been shown to be inactive in individuals with psychological disassociation (Meares, 2012).
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Dehydronorketamine (DHNK), or 5,6-dehydronorketamine, is a minor metabolite of ketamine which is formed by dehydrogenation of its metabolite norketamine. Though originally considered to be inactive, DHNK has been found to act as a potent and selective negative allosteric modulator of the α7-nicotinic acetylcholine receptor (IC50 = 55 nM). For this reason, similarly to hydroxynorketamine (HNK), it has been hypothesized that DHNK may have the capacity to produce rapid antidepressant effects. However, unlike ketamine, norketamine, and HNK, DHNK has been found to be inactive in the forced swim test (FST) in mice at doses up to 50 mg/kg.
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The occasional blue color of Emerald Lake is an indicator of the buried glacial ice. Since this color did not appear in 2016 despite low water levels, the main flow lobe of the glacier which touches the lake may now be inactive.
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In 2007, Easton joined Leeroy Stagger and Evan Phillips, performing as Easton, Stagger, Phillips. Easton and Stagger initially performed in 2008 as support acts for Phillips' band The Whipsaws.Official Website, Profile of The Whipsaws. Website appears to be inactive as of 2009.
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On March 22, 2018, InciWeb declared the Thomas Fire to be inactive and ceased providing updates. On June 1, 2018, the Thomas Fire was officially declared to be out, after more than two months in which no hotspots were detected within the perimeter of the burn area.
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Chymotrypsinogen must be inactive until it gets to the digestive tract. This prevents damage to the pancreas or any other organs. It is activated into its active form by another enzyme called trypsin. This active form is called π-chymotrypsin and is used to create α-chymotrypsin.
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Ironically, the Ravens had signed Stallworth to take Williams' former role as deep threat receiver, yet he himself would be inactive for much of the season with an injury. Williams finished his Ravens career with a total of 63 receptions, 1,008 yards, and four touchdowns on a 16.0 yard receiving average.
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In 1990 Spirit of Atlanta regained Finalist status, but their success would not last long. Financial and management challenges plagued the corps. From 1991 to 1993 the corps' competitive status declined. The financial problems culminated leading into the 1994 season, when the corps announced it would be inactive that summer.
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Latukan lies in an area of dominantly basaltic volcanoes west of the cordillera in central Mindanao. The Philippine Institute of Volcanology and Seismology (PHIVOLCS) lists Latukan as an inactive volcano, without any indication as to why it considers Latukan to be inactive. Like most volcanoes in southern Philippines, Latukan has not been well studied.
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An in vitro experiment showed lentinan stimulated production of white blood cells in the human cell line U937. Lentinan is thought to be inactive in humans when given orally and is therefore administered intravenously. The authors of an in vivo study of lentinan suggested that the compound may be active when administered orally in mice.
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Gast suffered an elbow injury during the spring of his senior year in high school, which required Tommy John surgery on May 1, 2007 and forced him to be inactive during most of his first year with the Florida State team. In 2009 Gast played for the Harwich Mariners of the Cape Cod League.
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Three active DNA methyltransferases have been identified in mammals. They are named DNMT1, DNMT3a, and DNMT3b. Recently, a fourth enzyme DNMT3c has been discovered specifically expressed in the male germline in the mouse. DNMT3L is a protein closely related to DNMT3a and DNMT3b in structure and critical for DNA methylation, but appears to be inactive on its own.
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The desolate, uninhabited island measures approximately , with over 90% of its surface permanently covered in ice. The volcano Mount Belinda is its most notable geographic feature, rising to above sea level. It was believed to be inactive prior to the sighting of low-level ash emission and suspected lava effusion in 2002 by the British Antarctic Survey.
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Dobrynskoye was a military air base in Vladimir Oblast, Russia. It is located near Dobrynskoye, north-east of Vladimir. Dobrynskoye was an airfield of the Soviet Air Force housing fighter aircraft which appeared on aeronautical charts in the 1970s and 1980s. By the 1990s the airfield disappeared from the charts, and is now believed to be inactive and abandoned.
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In mammals, there are three types of ADARs, 1, 2 and 3. ADAR1 and ADAR2 are found in many tissues in the body while ADAR3 is only found in the brain. ADAR1 and ADAR2 are known to be catalytically active while ADAR3 is thought to be inactive. ADAR1 has two known isoforms known as ADAR1p150 and ADAR1p110.
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At the mean pH of the laryngopharynx (pH = 6.8) pepsin would be inactive but could be reactivated upon subsequent acid reflux events resulting in damage to local tissues. Pepsin exhibits a broad cleavage specificity. Pepsin will digest up to 20% of ingested amide bonds . Residues in the P1 and P1' positions are most important in determining cleavage probability.
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The raisin moth has been observed to exhibit nocturnal flight patterns. It tends to be inactive during the day and begin significant activity at 7pm. Activity exponentially increases until it peaks at 8pm, when it then slowly levels off and reaches inactivity at 5am. Activity during this period consists of mating, as the moths do not forage in the adult phase.
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At high concentrations this enzyme will be inactive and serine will not be produced. At low concentrations of serine the enzyme will be fully active and serine will be produced by the bacterium. Since serine is the first amino acid produced in this family both glycine and cysteine will be regulated by the available concentration of serine in the cell.
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It should also be mentioned that all forms of Phospholipase C require calcium for activation, many of them possessing multiple calcium contact sites in the catalytic region. The only isoform that is known to be inactive at basal intracellular calcium levels is the δ subfamily of enzymes suggesting that they function as calcium amplifiers that become activated downstream of other PLC family members.
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The Global Humanitarian Forum encountered serious financial difficulties due to which the Forum had to dismiss its staff in March 2010.[1][2] On 31 March 2010 the Swiss Federal Department of Foreign Affairs announced that the Forum was over- indebted and obliged to cease its activity.[3] As of June 2, 2014, the WIFA Initiative seems to be inactive.
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Hotspots continued to persist within the perimeter of the Ranch Fire for another few months. On November 7, 2018, InciWeb stopped issuing updates on the Mendocino Complex and declared the incident to be inactive. On January 4, 2019, Cal Fire reported that the Mendocino Complex had fully been brought under control, extinguishing the fire 160 days after it had started.
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Sweeps to the supporting leg of the opponent with the shin or the top of the foot are allowed. Knees are permitted to the head, chest, sides, stomach and legs. Clinch fighting is allowed to go on as long as the fighters are perceived to be active and working. Should the referee judge the clinch to be inactive, he will break up the fighters.
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Lewis was signed by the Washington Redskins as an undrafted free agent on April 29, 2012. In early August, he suffered a groin injury that caused him to be inactive for the 2012 preseason. He was waived with an injury settlement on August 27. Lewis returned to the Redskins on May 14, 2013 following a successful tryout during the team's rookie mini- camp in early May.
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Uterine serpins are members of the A clade of the serine protease inhibitor (serpin) superfamily of proteins and are encoded by the SERPINA14 gene. Uterine serpins are produced by the endometrium of a restricted group of mammals under the influence of progesterone or estrogen. These proteins appear to be inactive protease inhibitors and may function during pregnancy to regulate immune function or participate in transplacental transport.
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Staphylococcus aureus beta toxin is a toxin produced by Staphylococcus aureus. It is a form of sphingomyelinase called sphingomyelinase C. This enzyme is toxic to a variety of cells, including erythrocytes, fibroblasts, leukocytes, and macrophages. Susceptible cells are subject to lysis of exposed sphingomyelin on their membrane surfaces. The beta toxin exhibits maximum activity at 10 °C, at 37 °C (normal body temperature) seems to be inactive.
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Another publication, again called The Chevron, appeared on campus in September 2013. Its editors consider it a continuation of both previous Chevron newspapers. However, unlike the critical nature of the 2010 Chevron, this revival often praises the Federation of Students and its regular writers do not operate under pseudonyms. The last issue was published in 2014, and the newspaper seems to be inactive since then.
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The core sample was reportedly contaminated and crystal morphology study was unsuccessful. Today, the rock glacier consists of three flow lobes. The main one may be inactive, the uppermost one is probably active, and the one in-between is probably extinct. On September 3, 2016, an amateur geologist found a meltwater pit in the uppermost flow lobe full of opaque glacial runoff and a small amount of exposed glacial ice.
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On 16 July 1993, the 40th was inactivated. With the United States' victory in the Cold War, the military began to demobilize. As part of this process, the squadron and its parent organization, the 317th Airlift Wing, were inactivated. At first it appeared that the 40th would be inactive for an indeterminate time, but the Air Force's senior leadership decided to move the squadron's designation to Dyess Air Force Base, Texas.
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After his retirement in 1984 Bruckmann did some consulting work for C&C; Yachts in Niagara-on-the-Lake. He was a hands-on man, a hiker of the Alps and daily frequenter of the YMCA who could not bear to be inactive. He once re-shingled a backyard shed the day after a major operation. He would go from watching European soccer matches to listening to Beethoven and Strauss.
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All these JNK pathway regulators assemble transport complexes, tied to kinesin-dependent vesicular transport. In this context, JIP1/2 act as cargo adaptors, binding to a motor protein and a cargo protein simultaneously. In addition to their "normal" cargoes (C-termini of transmembrane proteins), they also transport MAP2K and MAP3K enzymes, namely MKK7, DLK and MLK3. Kinases bound to the JIP1/2 scaffold are generally sequestrated and thought to be inactive.
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The traditional method of chewing the leaves has continued in modern use. However, salvinorin A is generally considered to be inactive when orally ingested, as salvinorin A is effectively deactivated by the gastrointestinal system.Siebert 1994. Therefore, in what's understood to be a modern innovation, the 'quid' of leaves is held in the mouth as long as possible in order to facilitate absorption of the active constituents through the oral mucosa.
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On May 26, 1983, a tsunami caused by a 7.7 magnitude earthquake in the Sea of Japan killed 107 people, including three in South Korea. Mount Ontake, thought to be inactive, had a series of eruptions in 1980. In 1981, the caldera lake volcano Lake Shikotsu erupted in Hokkaidō, followed in 1982 by Mount Tarumae, which is located on its shores. Mount Kusatsu-Shirane in Kusatsu, Gunma Prefecture, erupted in 1983.
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In the wild, Cupiennius salei are arboreal, living in trees and bushes, favoring plants such as banana with broad flat leaves and wide joints that provide shelter. Although they tend to generally be inactive, they are much faster than many other arachnids when provoked. Cupiennius salei is a nocturnal, "sit-and-wait" ambush predator behaving with a strong circadian rhythmicity. They hide during daylight, mostly under leaves, and emerge at dusk.
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Not a lot is known about the ecology of the eastern hooded scaly-foot, however research has shown that is primarily nocturnal, although populations in southern Victoria have been observed to be active during the day. They are also thought to be inactive during winter. Although usually encountered singly, occasional aggregations have been reported, possibly related to breeding Patchell, F., & Shine, R. (1986). Food habits and reproductive biology of the Australian legless lizards (pygopodidae).
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Aperture is the sum of setup and hold time. The data input should be held steady throughout this time period. Recovery time is the minimum amount of time the asynchronous set or reset input should be inactive before the clock event, so that the data is reliably sampled by the clock. The recovery time for the asynchronous set or reset input is thereby similar to the setup time for the data input.
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It can rehydrate by absorbing moisture through its ventral skin, and evaporative water loss occurs at a rate, indicative of a watertight skin. very lowPyke and White, p. 571. Some have been observed up to 400 m from the nearest body of water. During the winter months, the frog tends to be inactive, staying in one place, whereas it moves around during the warmer months to search for food and mating partners.
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At the time, the Conservatives held all 28 seats in Alberta. In January 2008, the Party of Alberta appeared to be inactive and had put its registration campaign on hold. As it was never registered with Elections Canada, no candidates could be run under the party's banner in the 2008 federal election. As of December 2008, the blog and website for the party were both inaccessible, indicating dissolution of the effort to organize the party.
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The Southern Poverty Law Center (SPLC) enumerates false statements made by TVC, including the claim that gay people travel door-to-door to steal American children and transform them into homosexuals. The SPLC also notes that TVC has a history of Islamophobic statements. Because of this, SPLC classified TVC as a hate group beginning in 2008. The SPLC removed the designation in 2018 because the group appeared to be inactive or defunct.
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The women arrive and after discovering the truth, (namely that it was merely a hoax) decide to make the best of the situation by spending two weeks vacationing on the island. At the end of the two-week time period, the ladies depart, leaving only Zack and Niki on the island. Shortly thereafter, a volcano, previously thought to be inactive, spontaneously erupts, threatening to destroy Zack's island. In the chaos, Niki escapes using Zack's jetpack.
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Rather it has 350 ordinary members and 25 Associate members which are affiliated to the Association. Only ordinary members are eligible to vote during elections. If any ordinary member is found to be inactive in terms of cricket activity for more than 3 years the Club to which he/she belongs is demoted as an Associate member and if the club is still inactive for 3 years it automatically loses its membership.
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A study by Public Health England in 2017 found that 41% of the 15.3 million English adults aged 40 to 60 do not walk for as much as 10 minutes continuously each month at a brisk pace. A quarter of the English population was found to be “inactive” – doing less than 30 minutes of activity per week. The heaviest-drinking 20% of the population drink almost two thirds of all alcohol consumed.
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This activity continued into the beginning of August, but the latter part of the month saw few tornadoes, as well as the start of September. The rest of September was slightly more active. The fall months had normal activity; however, a pattern shift at the end of November caused December as a whole to be inactive, even though the F4 storm in Tuscaloosa, Alabama was the second-deadliest December tornado since 1950.
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When the target gene is present, the alpha- fragment gene would be inactive and the alpha fragment won't be produced. In that case B-galactosidase will not be active. When the target gene is not found in the vector, the alpha fragment gene would be active, producing the alpha fragment and allowing for B-galactosidase to gain its activity. To trace the activity of B-galactosidase a colorless analog of lactose is used, X-gal.
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During the Sandinista revolution, many Chinese Nicaraguans emigrated to neighboring countries and the United States, causing the association to be inactive for approximately 10 years. That changed, however, in 1992, after some members approached the Chinese ambassador and expressed to him the importance to celebrate the Republic of China's Double Tenth Day (双十节). Other active clubs/associations include the Club de Jóvenes Chinos de Nicaragua (Club of Chinese Teens of Nicaragua).
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Jive Electro was a sublabel of the Zomba Group's Jive Records noted for releasing albums by Groove Armada, Hardknox, and Tangerine Dream as well as few remixes for the Madchester band The Stone Roses. The label was largely active between 1984 and 1987. Jive resurrected it in the 1998 to accommodate a boom in electronic music, but it appears to be inactive since Zomba and Jive were integrated into a major label structure in 2004.
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In 2002, Woodson suffered his first major injury since his freshman year at Michigan, suffering from a shoulder injury which caused him to be inactive for eight games. The shoulder injury came in the first half of the second game of the season. Despite the injury Woodson played the remainder of the game and was able to force a fumble.Shoulder sidelines Charles Woodson by Nancy Gay of the San Francisco Chronicle, posted September 19, 2002.
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Today, the image is in the Chapel of San Pedro or De las Reliquias. Traditionally, the image has been petitioned by those seeking release from restrictions or traps, especially financial problems or drug addiction or alcoholism. The cult to the Niño Cautivo is considered to be "inactive" by INAH. However, this particular image has made a comeback since 2000 as one to petition when a family member is abducted and held for ransom.
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Hepoxilins possess several activities (see hepoxilin#Physiological effect) whereas their trioxilin products are generally considered to be inactive. Accordingly, the soluble epoxide hydrolase metabolic pathway is considered to function in vivo to inactivate or limit the activity of the hepoxilins. The other fatty acid epoxide hydrolases cited in the Epoxide hydrolases section (above) have not be reported for hepoxilin- epoxide hydrolase activity, could possibly exhibit this, and therefore contribute to inactivating the hepoxilins.
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The first successful intrastate crowdfunding campaign pursuant to the Michigan Invests Locally Act (the MILE Act) was run by the Tecumseh Brewing Co., and was successfully closed at $175,000, in May 2014, on the multi-state platform Localstake. Under the Illinois Intrastate Offering Exemption the Secretary of State has approved the application of VestLo as a registered crowdfunding portal effective August 2016. However, the site appears to be inactive as of May 2019.
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Today, the image is in the Chapel of San Pedro or De las Reliquias. Traditionally, the image has been petitioned by those seeking release from restrictions or traps, especially financial problems or drug addiction or alcoholism. The cult to the Niño Cautivo is considered to be “inactive” by INAH. However, this particular image has made a comeback since 2000 as one to petition when a family member is abducted and held for ransom.
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Head coach Bruce Arians nicknamed him "knee-deep", explaining that you need to keep "A knee in his ass everyday" to keep him motivated. He started his rookie season as the Cardinals' third right tackle on their depth chart, behind veterans Earl Watford and Bobby Massie. During his rookie season, he was inactive for all 16 regular season games and both postseason contests. He was the only first round draft pick in 2015 to be inactive the entire season.
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However this compound has subsequently been sold as a "research chemical" and anecdotal reports suggest that at higher doses 4-HO-DBT is indeed an active hallucinogen, although somewhat weaker than other similar tryptamine derivatives. Several different isomers of this compound could be made (see DBT for a fuller discussion) but of these only the isobutyl isomer 4-HO-DIBT has been synthesised (mp 152-154 °C) and was also found to be inactive at a 20 mg dose.
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Yūki's motivation for Careless Monday was to take revenge against the society he hated. He was forced to work to support his ill parents and felt cheated by the system. In The King of Eden movie, he appears to be inactive, but he reveals to Tsuji that he has broken his phone in a bid to evade Mononobe, who is tracking him, resulting in his elimination from the game. He soon becomes obsessed with getting revenge against Takizawa.
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2C-H exhibits agonist activity in vitro at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal calcium mobilization. 2C-H was found to be inactive in NCI In Vivo Anticancer Drug Screens for tumor model L1210 Leukemia. It was found to be an active Alpha-1 adrenergic receptor agonist in rabbit ear arteries. It has binding affinity towards 5-HT2C and 5-HT2A receptors in rats.
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NREM sleep is characterized by decreased global and regional cerebral blood flow. It constitutes ~80% of all sleep in adult humans.Parmeggiani (2011), Systemic Homeostasis and Poikilostasis in Sleep, passim. Initially, it was expected that the brainstem, which was implicated in arousal would be inactive, but this was later on found to have been due to low resolution of PET studies and it was shown that there is some slow wave activity in the brainstem as well.
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When oxygen levels in the cell are low, it will limit its energy expenditure through the inhibition of protein synthesis. Under hypoxic conditions, hypoxia inducible factor one alpha (HIF1A) will stabilize and activate transcription of REDD1, also known as DDIT4. After translation, this REDD1 protein will bind to TSC2, which prevents 14-3-3 from inhibiting the TSC complex. Thus, TSC retains its GAP activity towards Rheb, causing Rheb to remain bound to GDP and mTORC1 to be inactive.
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In traditional gene knockout, embryonic death from a gene mutation can occur, and this prevents scientists from studying the gene in adults. Some tissues cannot be studied properly in isolation, so the gene must be inactive in a certain tissue while remaining active in others. With this technology, scientists are able to knockout genes at a specific stage in development and study how the knockout of a gene in one tissue affects the same gene in other tissues.
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On December 11, head coach Mike Shanahan announced that Griffin would be inactive for last three games of the season and that Kirk Cousins would finish the season as the starter. He claimed that it was done in order to eliminate risk of further injury to Griffin. He finished the 2013 season with 3,203 passing yards, 16 passing touchdowns, and 12 interceptions to go along with 86 carries for 489 rushing yards and a rushing touchdown.
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The orange-bellied parrot was first bred successfully in 1973 by South Australian aviculturist Fred Lewitska, after five years with no success. He repeated his success in 1974 before being directed to release the birds into the wild by authorities. He found that the species could be inactive in an aviary and was prone to obesity, like the related rock parrot. Victorian birdwatcher, artist and photographer, Len Robinson, bred orange-bellied parrots in suburban Melbourne between 1998 and 2006.
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In the 1960s, underground fractures were uncovered by oil companies in Puget Sound. These were believed to be inactive through the 1990s. In the 1980s, geophysicists Tom Heaton and Hiroo Kanamori of Caltech compared the generally quiet Cascadia to more active subduction zones elsewhere in the Ring of Fire. They found similarities to faults in Chile, Alaska, and Japan's Nankai Trough, locations known for megathrust earthquakes, a conclusion that was met with skepticism from other geophysicists at the time.
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This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis.
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The stripe cusk-eel is a benthic species which burrows tail first into soft substrates such as sand or mud. They remain hidden during the day and come out of their burrows at night to hunt. They occur in inshore waters in Spring and Fall but their wintering habits are little known, they may move offshore or they may be inactive and remain buried in the substrate. They feed on small crustaceans and fishes smaller than themselves.
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Hardaway Jr. with the Hawks in 2017. On June 25, 2015, Hardaway was traded to the Atlanta Hawks in exchange for the draft rights to Jerian Grant. Despite averaging 24 points in the Hawks' final two preseason contests, Hardaway was listed as inactive for the season opener. However, on the same day that they announced he would be inactive for the opener, the Hawks announced that they picked up the team option for the 2016–17 season.
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However, Pouncey was injured in the AFC championship game and would be inactive for Super Bowl XLV. The Steelers had one of the league's top defenses, leading the NFL in sacks (48), and fewest points (14.5) and rushing yards (62.8) allowed per game, while ranking second in fewest total yards (276.8). The line was anchored by pro bowl end Brett Keisel. The Steelers also had four excellent linebackers: LaMarr Woodley, James Harrison, James Farrior, and Lawrence Timmons.
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On various independent labels, The Hookers released two more full length albums: Black Visions of Crimson Wisdom in 1999 and Equinox Beyond Tomorrow Volume 1 in 2001. The band recorded the Blood Over Germany live album in 2001 on Century Media Records. After 2001, The Hookers were considered to be inactive as their heretofore intensive touring and release schedule was curtailed. Their song "The Legend of Black Thunder" was included on Tony Hawk's Underground videogame soundtrack in 2003.
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By September 2012 DistroWatch had changed the status to "active" again, and on 6 August 2013, the first version directly based on Debian, gNewSense 3 "Parkes", was released. Under the few discussions in the Trisquel forums gNewSense was again said to be inactive in 2017, while in 2019 after gNewSense had not had releases in several years, active development was restarted with the merging of the Skeleton GNU/Linux project into it and a new maintainer taking over.
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Figurine are an American electronica group. The band members, friends since high school, use the pseudonyms David Figurine (Forster David Rudolph), James Figurine (Jimmy Tamborello) and Meredith Figurine (Meredith Landman). While the band seems to be inactive , all three members are also involved in other bands or have released solo work under their respective Figurine monikers. Mainly a long distance collaboration, the band was a precursor to James Figurine/Tamborello's later, more commercially successful project The Postal Service.
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The widest continental shelf on the planet is found in the Arctic Ocean, extending more than 1000 kilometers outward from Siberia and Alaska. Consequently, much of the basin is very shallow. On the other hand, the Arctic Ocean contains the deepest, slowest spreading mid-ocean ridge on the planet which, until 2003, was thought to be inactive volcanically. Since then, however, a dozen active volcanoes have been discovered, illustrating the limited information available for the difficult- to-study Arctic Ocean.
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LSD-Pip is a compound from the ergoline family, related to LSD but with the N,N-diethyl substitution replaced by a piperidine group. It is more potent than the corresponding pyrrolidine and morpholine analogues (LPD-824 and LSM-775 respectively), but is still several times less potent than LSD as a 5-HT2A agonist. Early studies suggested this compound to be inactive as a psychedelic in humans, though this does not seem to have been confirmed by any more recent work.
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On January 12, 2018, the U.S. Forest Service declared the Thomas Fire 100 percent contained, at 281,893 acres. Afterward, Los Pedros National Forest officials continued monitoring the burn area of the Thomas Fire for hotspots. On March 22, 2018, InciWeb declared the Thomas Fire to be inactive and ceased providing updates. On June 1, 2018, the Thomas Fire was officially declared to be out, after more than two months in which no hotspots were detected within the perimeter of the burn area.
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The GameStick website began displaying a message saying that they would be shutting down the service after two years of operation, stating that after January 9th, 2017, the storefront would be inactive. In December 2017, the GameStick website showed only the goodbye message and presented an expired SSL certificate. It is unlikely the service will ever return and the device itself is indirectly discontinued. Attempting to visit the GameStick website again will cause a redirection to a Turkish soccer website (www.panamhandball.org).
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It is still unclear why she chose to be inactive during this crucial period of seizing power, although she had interrupted her revolutionary activities for the sake of her children in 1905, 1908 and 1913.Elwood, p. 42 On 19 April, she did attend a Moscow Oblast Conference, in which she made forceful speeches on the necessity of the election of officers and the fraternization of combatant forces, as well as on the opportunism of the Second International's leaders.Elwood, p.
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This is the process of disguising medically active molecules with lipophilic molecules that allow it to better sneak through the blood–brain barrier. Drugs can be disguised using more lipophillic elements or structures. This form of the drug will be inactive because of the lipophilic molecules but then would be activated, by either enzyme degradation or some other mechanism for removal of the lipophilic disguise to release the drug into its active form. There are still some major drawbacks to these pro-drugs.
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According to our current knowledge, KSRs also participate in the same pathway as Raf, although they only play an auxiliary role. With a very poor intrinsic kinase activity, they were long thought to be inactive, until their catalytic activity was finally demonstrated in recent years. But even then, they contribute only negligibly to MKK1 and MKK2 phosphorylation. The main role of KSR appears to be to provide a heterodimerization partner to Raf enzymes, greatly facilitating their activation by means of allostery.
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Although article 21.1 of the constitution of the German state of Hesse provided capital punishment for high crimes, this provision was inoperative due to the federal ban on the death penalty ("Bundesrecht bricht Landesrecht." (article 31 GG) – Federal law overrides state law.article 31 GG It would, of course, also be inactive due to lack of an implementing penal law today.). The capital punishment provision was finally scrapped from Hesse's state constitution in 2018 by popular vote, with 83% of the votes in favor.
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On 6 June 2005, the British Ministry of Defence announced that Invincible would be inactive until 2010 but available for reactivation at eighteen months' notice. She was decommissioned on 3 August 2005, twenty months after an extensive refit that had been intended to give her ten more years of service. succeeded her as the service's flagship. The Royal Navy maintained that Invincible could have been deployed had the need arisen and that Navy policy assumed she was still an active aircraft carrier.
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The Ferguson Fire was a wildfire in the Sierra National Forest, Stanislaus National Forest and Yosemite National Park in California in the United States. The fire was reported on July 13, 2018, burning , before it was 100% contained on August 19, 2018. Interior areas of the fire continued to smolder and burn until September 19, 2018, when InciWeb declared the fire to be inactive. The Ferguson Fire was caused by the superheated fragments of a faulty vehicle catalytic converter igniting vegetation.
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White- bellied fat-tailed mouse opossums are nocturnal animals with good climbing abilities, although they prefer to spend most of their time on the ground. They nest in natural cavities, either in trees or shrubs, or beneath rocks. Although they do not truly hibernate through the winter, they do enter torpor if temperatures fall below around 15 °C, and therefore may be inactive through much of the winter period. In the wild, they rarely drink, being able to subsist on the water in their food.
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The program UPPAAL introduce the notion of inactive clocks. A clock is inactive at some time if there is no possible future in which the clock's value is checked without being reset first. In our example above, the clock c_i is considered to be inactive when the elevator arrive at floor i, and remains inactive until someone call the elevator at floor i. When allowing for inactive clock, a valuation may associate a clock x to some special value \bot to indicate that it is inactive.
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Active protection measures which need power or external activation to trigger the protection action can be used to (i) suppress fire, such as water/foam sprinklers and (ii) isolate process unit using equipment such as emergency shutdown (ESD) systems. An active protection measure usually consists of three elements: (i) a detection system, (ii) a treatment system, and (iii) an actuation system. In order to ensure the performance of active protection measures, all the above three elements should be inactive, otherwise, the protection doesn't work.
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A piconet is an ad hoc network that links a wireless user group of devices using Bluetooth technology protocols. A piconet consists of two or more devices occupying the same physical channel (synchronized to a common clock and hopping sequence). It allows one master device to interconnect with up to seven active slave devices. Up to 255 further slave devices can be inactive, or parked, which the master device can bring into active status at any time, but an active station must go into parked first.
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The launch of a record label entitled "Brown Punk" was announced in mid-2007 that was a collaboration between Tricky and former Island Records executive Chris Blackwell. At the time, Tricky said: "Brown Punk represents a positive movement where you find intellectuals mixing with the working class, rock mixing with reggae and indie mixing with emo." The Dirty, The Gospel, Laid Blak Mexican band My Black Heart Machine were acts that were signed to the label, but as of October 2013, the label appears to be inactive.
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The High Power laser Energy Research facility (HiPER), is a proposed experimental laser-driven inertial confinement fusion (ICF) device undergoing preliminary design for possible construction in the European Union. , the effort appears to be inactive. HiPER was designed to study the "fast ignition" approach to generating nuclear fusion, which uses much smaller lasers than conventional ICF designs, yet produces fusion power outputs of about the same magnitude. This offers a total "fusion gain" that is much higher than devices like the National Ignition Facility (NIF), and a reduction in construction costs of about ten times.
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This anchor would then restrict the activity of translated PKMzeta, an important plasticity related protein, to this location. A different model proposes that short-term synaptic changes induced by the stimulus are themselves the tag; subsequently delivered or translated protein products act to strengthen this change. For example, the removal of AMPA receptors due to low-frequency stimulation leading to LTD is stabilized by a new protein product that would be inactive at synapses where internalization had not occurred. The tag could also be a latent memory trace, as another model suggests.
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The statement was widely interpreted in the English-speaking world as meaning that France would exercise its right as a Permanent Member of the Security Council to veto any resolution at any time ("whatever the circumstances") to use force against Iraq. Following the overthrow of the former Iraqi government, the Iraq Survey Group led an exhaustive search of Iraq for WMD. Ultimately, while over 500 "degraded" chemical warheads were found, no deployable WMD of any kind were found and all WMD production facilities had been found to be inactive since 1991.
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For example, Cosmoe and BlueEyedOS (both of which remain incomplete, and now appear to be inactive) took an existing Linux or BSD kernel and re- implemented Be's APIs on top of it; this broke binary code compatibility with BeOS R5 and significantly deviated from the original design. By contrast, OpenBeOS planned an almost complete rewrite of the system, maintaining binary and source code compatibility. This should allow any existing BeOS R5 programs to run on the new system without being recompiled. A first release of OpenBeOS was made in 2002.
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The next night on Raw, General Manager Kurt Angle informed the audience that both men were injured. The following week, Strowman, wearing a sling on his arm, indicated that he would target the Universal Champion after finishing off Reigns. Later that night, Reigns attacked Strowman during the latter's match, targeting his arm with a steel chair. Strowman required surgery and was expected to be inactive for up to six months. On the June 19 episode of Raw, Reigns proclaimed himself to be the number one contender for the Universal Championship at SummerSlam.
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Houston Camanachd Club was the third shinty team to be established in North America in the Modern Era in 2005. The club was founded by Warren Clifford, a shinty player from the NCCC. The developmental aim of the club was to compete against the other shinty teams in North America. However, their extreme distance from any other club, the rest of the clubs being on the Western Seaboard, meant that Houston did not develop into a fully blown club and as of 2010 can be considered to be inactive.
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He is said to have denied, contrary to the standard Stoic view, that the cosmos is an animate being,Diogenes Laërtius, vii. 143 and he suggested that it was not the whole world which was divine, but only the ether or sphere of the fixed stars.Diogenes Laërtius, vii. 148 He argued that the world was eternal,Philo, De aeternitate mundi 76–77 in particular, he rejected the Stoic conflagration (ekpyrosis) because god or the World-Soul would be inactive during it, whereas it exercises Divine Providence in the actual world.
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The active sites of ALAS utilize three key amino acid side chains: Arg-85 and Thr-430 and Lys-313. Although these three amino acids have been identified to allow this reaction to proceed, they would be inactive without the addition of cofactor pyridoxal 5’-phosphate (PLP) whose role in this synthesis is detailed in the image below. Before the reaction can begin, the PLP cofactor binds to the lysine side chain to form a Schiff base that promotes attack by glycine substrate. Lysine acts as a general base during this mechanism,.
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The New Zealand Herald later reported that Yang did not disclose his links to the schools in his citizenship applications and instead substituted "partner" universities. Yang also confirmed that he had been a member of the Chinese Communist Party but claimed to be inactive since moving to New Zealand in 1994. In late June 2020, Yang came under further criticism from media and New Zealand First leader Winston Peters for refusing to give English-language interviews since the spy allegations surfaced and only granting interviews to local ethnic Chinese media.
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On the May 8 episode of Raw, Strowman indicated his desire to face Lesnar for the Universal Title after he was finished with Reigns. Later that night, Reigns attacked Strowman during his match against Kalisto, targeting his arm with a steel chair. It was then revealed that Strowman required surgery on his injured arm, and would be inactive for up to six months. Due to Strowman's situation and the need for a number one contender, General Manager Kurt Angle scheduled a #1 contender's Extreme Rules fatal five-way match for Extreme Rules between Reigns, Rollins, Joe, Bálor, and Wyatt.
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Vick played decently in that stretch, going 40–66 with 2 touchdowns and 1 interception, while also rushing for 104 yards on 15 carries (his other five carries were kneel downs). Vick suffered a hamstring injury in a win against the Arizona Cardinals, being replaced by Landry Jones, which led to him missing six games, and by then Roethlisberger was healthy enough to play. Despite continual injuries to Roethlisberger and the team not signing another quarterback throughout the season, Vick would be inactive the remainder of the season, leading some sports commentators to speculate that Vick's playing career may be over.
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It is the organism's physical properties which directly determine its chances of survival and reproductive output, but the inheritance of physical properties is dependent on the inheritance of genes. Therefore, understanding the theory of evolution via natural selection, requires understanding the genotype–phenotype distinction. The genes contribute to a trait, and the phenotype is the observable expression of the genes (and therefore the genotype that affects the trait). If a white mouse had recessive genes that caused the genes responsible for color to be inactive, its genotype would be responsible for its phenotype (the white color).
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The first catalytic domain of Type R2B RPTPs is considered the active phosphatase domain, whereas the second phosphatase domain is thought to be inactive. Mutations in the second phosphatase domain of PTPrho, however, result in a reduction of phosphatase activity of PTPrho. Deletion of the second tyrosine phosphatase domain in colorectal cancer cells also reduces PTPrho catalytic activity, again demonstrating that the second phosphatase domain of PTPrho does regulate catalytic activity, either directly or indirectly. Catalytic activity of PTPrho may also be regulated by tyrosine phosphorylation of the wedge domain of the first tyrosine phosphatase domain on tyrosine 912 by Fyn tyrosine kinase.
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The chemical inertness of the s electrons in the lower oxidation state is not always married to steric inertness (where steric inertness means that the presence of the s electron lone pair has little or no influence on the geometry of the molecule or crystal). A simple example of steric activity is that of SnCl2 which is bent in accordance with VSEPR. Some examples where the lone pair appears to be inactive are bismuth(III) iodide, BiI3, and the anion. In both of these the central Bi atom is octahedrally coordinated with little or no distortion, in contravention to VSEPR theory.
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The club was founded on 1 January 1912 as "Club Atlético Almirante Brown". The first uniform kit acquired by the club were the striped black and yellow worn by Uruguayan CURCC (predecessor of current club Peñarol), that were the only available in stores. On 21 March 1915 the club changed its name to "Almirante Brown Athletic Club" and one year later it affiliated to Amateur Football Association where the team took part of Tercera de Ascenso, the last division of Argentine football league system. It only lasted one season so the club would be inactive since 1919.
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Modafinil acid (code name CRL-40467), also known as modafinilic acid or modafinil carboxylate, is the major metabolite of modafinil, and one of the two major metabolites of modafinil – the other being modafinil sulfone. Modafinil acid is also a metabolite of the modafinil prodrug, adrafinil, and the (R)-(–)-enantiomer is a metabolite of armodafinil, the (R)-(–)-enantiomer of modafinil. Modafinil acid seems to be inactive, and similarly to modafinil sulfone, does not appear to contribute to the wakefulness- promoting/psychostimulant effects of modafinil. In the breakdown process of modafinil, modafinil is primarily hydrolyzed by an esterase or amidase enzyme into modafinil acid.
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Sportive lemurs have been found to be inactive for around 50% of their waking time, to rest without much motion for up to 2 hours at a time and to travel on average only per night. Prolonged rates of inactivity presumably allow the digestion and detoxification of low quality food and reduction of overall energy expenditure. The Sahamalaza sportive lemur attends other species’ alarm calls for predator alerts, a habit confirmed by experiments: when the call of a harrier hawk (a predator to Sahamalaza lemurs) was played near them, they became more alert and scanned the sky.
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However, as long as these operational amplifiers are used in a typical high- gain negative feedback application, these protection circuits will be inactive. The input bias and leakage currents described below are a more important design parameter for typical operational amplifier applications. ;Non-zero output impedance: Low output impedance is important for low- impedance loads; for these loads, the voltage drop across the output impedance effectively reduces the open loop gain. In configurations with a voltage- sensing negative feedback, the output impedance of the amplifier is effectively lowered; thus, in linear applications, op-amp circuits usually exhibit a very low output impedance.
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In November 2009, Leftöver Crack toured Australia and New Zealand for the first time in their career. However, the line-up for all of the shows consisted of Stza, guitarist Frank Piegaro (of Star Fucking Hipsters/Degenerics) and two Australians filling in - Alex Flamsteed (Hereafter) & Chris Cox (Phalanx). Following the Australian tour, Stza stated at a house show in West Auckland that Leftöver Crack would most probably be inactive in the future, much like Choking Victim before them. This coincided with the increased rate of activity from Star Fucking Hipsters, which has become his main creative outlet as of late.
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An example is eszopiclone (Lunesta), which is just a single enantiomer of an older racemic drug called zopiclone. One enantiomer is responsible for all the desired effects, while the other enantiomer seems to be inactive, so the dose of eszopiclone is half that of zopiclone. In chemical synthesis of enantiomeric substances, non-enantiomeric precursors inevitably produce racemic mixtures. In the absence of an effective enantiomeric environment (precursor, chiral catalyst, or kinetic resolution), separation of a racemic mixture into its enantiomeric components is impossible, although certain racemic mixtures spontaneously crystallize in the form of a racemic conglomerate, in which crystals of the enantiomers are physically segregated and may be separated mechanically (e.g.
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A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA. They are important animal models for studying the role of genes which have been sequenced but whose functions have not been determined. By causing a specific gene to be inactive in the mouse, and observing any differences from normal behaviour or physiology, researchers can infer its probable function. Mice are currently the laboratory animal species most closely related to humans for which the knockout technique can easily be applied.
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The future King Philip II came to Salamanca for his marriage to Maria Manuela, Princess of Portugal in 1543. He was concerned about the number of prostitutes in the city and issued an edict that prostitutes should leave the city's Casa de la Mancebía during the period of annual abstinence (Lent, Holy Week and Easter). They were to be inactive and remain outside the city walls on the left bank of the river during this period. On the afternoon of the Monday after Easter, led by Padre Putas (one of the most coveted official positions of the time), they returned to the city, crossing the river in boats that the students had decorated.
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The future King Philip II came to Salamanca for his marriage to Maria Manuela, Princess of Portugal in 1543. He was concerned about the number of prostitutes in the city and issued an edict that prostitutes should leave the city's Casa de la Mancebía during the period of annual abstinence (Lent, Holy Week and Easter). They were to be inactive and remain outside the city walls on the left bank of the river during this period. On the afternoon of the Monday after Easter, led by Padre Putas (one of the most coveted official positions of the time), they returned to the city, crossing the river in boats that the students had decorated.
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The Popular Revolutionary Resistance Organization – PRRO (Arabic: التنظيم الثوري للمقاومة الشعبية transliteration Al-Tanzim al-Thawri lil-Muqawama al- Sha'abiyah) or Organisation de la Resistance Populaire Révolutionnaire (OPPR) in French, was a Phoenicist-oriented, anti-Syrian Lebanese Christian underground terrorist group that emerged in March 1987, being responsible for a single combined bomb-and-rocket attack on a West Beirut hotel. Four residing Syrian intelligence officials were wounded in the course of action, and although the group warned of forthcoming attacks, little was heard of them since. It has been suggested that the PRRO was simply a cover for the Lebanese Liberation Front or a splinter faction, but is now considered to be inactive.
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Frozen mountain stone wētā in the Southern Alps, New Zealand Mountain stone wētā can survive being frozen solid over winter and are estimated to be inactive for at least 5 months of the year. During winter H. maori are often immobile with ice crystals on their cuticle, when touched the individuals appear to be frozen solid on warm days however, they can be found thawed and active under rocks. While the wētā are immobile they are in a state of suspended animation, they can survive up to 17 days in temperatures of about -10 °C. At temperatures below -10 °C, approximately 85% of their body water is crystallized, one of the highest ice contents known for any animal.
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On the February 19 episode of SmackDown, a video package aired, promoting Jackson's return to the brand. He made his return on the March 5 episode of SmackDown without Regal, who instead joined Raw, and defeated Jimmy Wang Yang. On April 10, 2010 at a house show in Glasgow, Scotland, Jackson suffered a tear in his right quadriceps muscle during a match against Kane, and was expected to be inactive for approximately six months. During his injury, Jackson was drafted to the Raw brand as part of the 2010 WWE Supplemental Draft. Jackson made his return to the ring on September 13, 2010, defeating Zack Ryder in a dark match prior to the Raw tapings.
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Previous missile designs normally used two single-purpose computers; one ran the autopilot that kept the missile flying along a programmed course, and the second compared the information from the inertial platform to the target coordinates and sent any needed corrections to the autopilot. To reduce the total number of parts used in Minuteman, a single faster computer was used, running separate routines for these functions. Since the guidance computer would be inactive while the missile sat in the silo, the same computer was also used to run a program that monitored the various sensors and test equipment. With older designs this had been handled by external systems, requiring miles of extra wiring and many connectors.
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2-Bromo-LSD, also known as BOL-148, is a derivative of lysergic acid invented by Albert Hofmann, as part of the original research from which the closely related compound LSD was also derived. 2-bromo-LSD was found to be inactive as a psychedelic and so was comparatively little researched for many years, although its similar behavior in the body made it useful for radiolabelling studies. It was found to bind to many of the same receptors as LSD, but acting as a neutral antagonist rather than an agonist. However its generally similar behavior to LSD in some respects has shown to be very useful in one specific area, the treatment of cluster headaches.
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He was named the third tight end to start the regular season, behind Ertz and Celek. He was inactive for the Philadelphia Eagles' season-opening 29–10 victory over the Cleveland Browns after suffering a calf injury. During the game, Brent Celek displaced his rib and was expected to be inactive the following game with Burton as his replacement. On September 19, 2016, Burton caught five passes for 49-yards and scored his first career touchdown reception during a 29–14 victory at the Chicago Bears. On October 16, 2016, Burton earned his first career start and made one catch for a seven- yard gain as the Eagles lost 27–20 at the Washington Redskins.
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Phthalimide derivatives were seen to be inactive, while saccharin derivatives were seen to be fair inhibitors of these enzymes. Gabriel-Colman Rearrangement Example 1 In a study of the derivatives of 3-Oxo-1,2-benzoisothiazoline-2-acetic acid 1,1-dioxide, the Gabriel–Colman rearrangement was employed in the conversion of Isopropyl (1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)acetate to Isopropyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide, as shown above. This reaction has shown a percent yield of 85%. Gabriel-Colman Rearrangement Example 2 In another study, N-phthalimidoglycine ethyl ester was used to synthesize 4-hydroxyisoquinoline through use of a Gabriel–Colman rearrangement, as shown above.
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In 1953 his tuberculosis was found to be inactive and Seifert declared to have a reduced earning capacity of 30%, though any causality between his illness and his imprisonment during the war was denied. Seifert contested this, accused the doctors of creating false medical reports and complained in long letters to various authorities about his problems. In August 1954 Seifert was examined by a public health officer, who was of the opinion that he was not in need of a regimen, but suggested that he could be sent to a sanatorium for observation. The doctor also noted in his report that Seifert was a mentally devious person with no will to recover.
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Normal females possess two X chromosomes, and in any given cell one chromosome will be active (designated as Xa) and one will be inactive (Xi). However, studies of individuals with extra copies of the X chromosome show that in cells with more than two X chromosomes there is still only one Xa, and all the remaining X chromosomes are inactivated. This indicates that the default state of the X chromosome in females is inactivation, but one X chromosome is always selected to remain active. It is understood that X-chromosome inactivation is a random process, occurring at about the time of gastrulation in the epiblast (cells that will give rise to the embryo).
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DAO acts in the brain to oxidize specific D-amino acids using the FAD region (flavin adenine dinucleotide region) and is commonly thought to be produced in the hindbrain, although there is new evidence of DAO expression in the forebrain as well. The DAO present in the forebrain seems to be inactive, however, causing speculation on the topic of DAO function in the forebrain as opposed to the hindbrain where the function is more well-known. The consensus is that DAO is produced and is active in glial cells, most specifically in cerebellar type-1 and type-2 astrocytes, and the D-serine amino acid that is produced by DAO in these cells has been shown to increase synaptic NMDA receptor activity.
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HDAC1 & HDAC2 are in the first class of HDACs are most closely related to one another. By analyzing the overall sequences of both HDACs, their similarity was found to be approximately 82% homologous. These enzymes have been found to be inactive when isolated which led to the conclusion that they must be incorporated with cofactors in order to activate their deacetylase abilities. There are three major protein complexes that HDAC 1 & 2 may incorporate themselves into. These complexes include Sin3 (named after its characteristic protein mSin3A), Nucleosome Remodelling and Deacetylating complex (NuRD), and Co-REST. The Sin3 complex and the NuRD complex both contain HDACs 1 and 2, the Rb-associated protein 48 (RbAp48) and RbAp46 which make up the core of each complex.
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By following the contact information on Noone, McCaleb and Jaye Winston find the Code Killer's files, which prove that he had deliberately killed three people to get McCaleb a new heart. Although McCaleb is thus cleared, the fact that Gloria's death was directly due to his illness creates a rift in his increasingly personal relationship with Graciela and her nephew Raymond, Gloria's son. McCaleb, who is still supposed to be inactive, secretly continues to trace the Code Killer from information that he learned during his interview with "Noone" and drives to a location in Baja California that matches one Noone described. He then finds and is overpowered by the Code Killer, who tells him that he has kidnapped Graciela and Raymond and buried them alive.
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On 2 February 2009, Dacourt joined English side Fulham on loan until the end of the 2008–09 season after being signed by Roy Hodgson. However, he had to settle for being confined to mainly substitute appearances due to the impressive form of Fulham's midfield and also Dacourt picking up some injury niggles, Dacourt's move to Fulham was not made permanent come the summer, Dacourt briefly returned to Inter where his contract then expired and he became a free agent. Dacourt signed a one-year contract with Standard Liège on 23 September 2009. He was brought in to replace Steven Defour who had an injury on his foot and should be inactive for three months, Defour was the central midfield partner to Axel Witsel.
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2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine is a drug originally researched as a potential opioid analgesic, but was found to be inactive in this assay, and relatively toxic to mice. Subsequently it was found to possess activity as an agonist at nicotinic acetylcholine receptors during the course of work that ultimately led to the discovery of the anti-smoking drug varenicline. More recently this chemical compound is claimed to have been sold as a designer drug under the name A3A, but since the anecdotally reported effects of the product sold under this name do not seem to bear any resemblance to the known pharmacology of genuine 2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine, it seems unlikely that this is actually the compound being sold.
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The app was also found to be able to download and install arbitrary applications, although this required approval by the user. Furthermore, the app restarted after being closed and continued running in the background and sending telemetry requests while the user believes it to be inactive. Because of the far-reaching permissions to use the app means that servers owned by DJI or Weibo "have almost full control over the user’s phone." Furthermore, Google’s app store was unable to do any verification of any updates pushed by DJI. No issues related to hidden updates were found on the app’s iOS version. In August 2020, Synacktiv alleged that DJI’s Pilot app shares many of the same issues present in DJI GO 4, which DJI denied.
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There are four symmetrical isomers of DBT which can be made, or ten isomers in total if unsymmetrical substitution is used. Of these only the n-butyl analogue DBT is known to be active in humans; the isobutyl, sec-butyl, and tert-butyl isomers DIBT, DSBT and DTBT have never been tested and only DBT and DIBT were made by Shulgin. 400px The unsymmetrical isomers BIBT, BSBT, BTBT, IBSBT, IBTBT and SBTBT are also possible but have never been made and no predictions have been made about their activity. Shulgin speculates that the s-butyl isomer DSBT may be more potent than the straight chain compound DBT, but that the more highly branched DIBT and DTBT would probably be inactive due to the bulk of the substituent group.
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Removal time is the minimum amount of time the asynchronous set or reset input should be inactive after the clock event, so that the data is reliably sampled by the clock. The removal time for the asynchronous set or reset input is thereby similar to the hold time for the data input. Short impulses applied to asynchronous inputs (set, reset) should not be applied completely within the recovery-removal period, or else it becomes entirely indeterminable whether the flip-flop will transition to the appropriate state. In another case, where an asynchronous signal simply makes one transition that happens to fall between the recovery/removal time, eventually the flip-flop will transition to the appropriate state, but a very short glitch may or may not appear on the output, dependent on the synchronous input signal.
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Additionally, Noel was recovering from an anterior cruciate ligament injury suffered while in college, strongly indicating that he would not be able to make an immediate impact for the Sixers as he would be inactive to start the season. The Sixers used the 11th pick in the draft to select Michael Carter-Williams as Holiday's replacement as the starting point guard. The Sixers chose Arsalan Kazemi with the 54th overall pick, making Kazemi the first Iranian chosen in the NBA draft. Following the Holiday trade, many of the team's returning players were either waived or left the team in free agency, most notably Andrew Bynum; of the 15 players on the team's roster during their final game of the 2012–13 season, only six remained with the team by January 1, 2014.
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Quebec riding associations, which had tended to be inactive between elections, were overrun with Clark and Mulroney organizers in short order and many held votes within the first week of the campaign with set delegate slates. Clark's supporters tended to be former Union Nationale, Créditiste, and nationalist voters, while Mulroney's support came primarily from disaffected Liberals. These contests were especially fierce: voters only had to be PC members for five days before the vote was held, leading to many "five day wonders" that simply paid the $3 membership fee, with party operators receiving $10 commissions per voter. The lack of an age limit meant that children as young as 9 were recruited by the Clark and Mulroney camps to vote, with one 15-year- old recruiting 20 of her classmates.
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The city of Lakeport, communities of Kelseyville, Lucerne, Upper Lake, Nice, Saratoga Springs, Witter Springs, Potter Valley, and Finley, parts of Hopland, and the tribal communities of Hopland Rancheria, Big Valley Rancheria, and Habematolel Pomo of Upper Lake were evacuated. The smaller River Fire was the first fire in the complex to be contained, reaching full containment on August 13, while the Ranch Fire continued to burn for more than a month after that, with flames on the northern flank of the Ranch Fire pushing eastward from the Snow Mountain Wilderness into Glenn County. The Ranch Fire finally reached full containment during the evening of September 18. However, the Ranch Fire continued to burn deep within containment lines until November 7, when the fire was declared to be inactive.
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It is likely that it was captured from a solar orbit in the early 1970s, although the capture may have occurred as early as the mid-1960s. Several other observers found images of the comet in precovery images obtained before March 24, including Kin Endate from a photograph exposed on March 15, S. Otomo on March 17, and a team led by Eleanor Helin from images on March 19. An image of the comet on a Schmidt photographic plate taken on March 19 was identified on March 21 by M. Lindgren, in a project searching for comets near Jupiter. However, as his team were expecting comets to be inactive or at best exhibit a weak dust coma, and SL9 had a peculiar morphology, its true nature was not recognised until the official announcement 5 days later.
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After his performance against the Jets, Jackson was named AFC Player of the Week for week 15. In Week 16 against the Cleveland Browns, Jackson was held to 38 passing yards and a lost fumble in the first 28 minutes, before exploding for 142 yards and two touchdowns in the last two minutes before halftime. He added a third touchdown pass in the second half of the 31–15 win, setting the Ravens single season record for touchdown passes at 36, finishing with 238 passing yards and 103 rushing yards. On the day after the Ravens' victory over the Browns, and due to the Ravens' having clinched home-field advantage, head coach John Harbaugh announced that Jackson, guard Marshal Yanda, safety Earl Thomas and defensive tackle Brandon Williams would be inactive for the Week 17 game against the Pittsburgh Steelers.
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As for the Croats: "what will become of the borders of the Croatian unit and what rights the Croats will have in the new state of the future will depend solely on them". He explained that "if they continue to be inactive, there will be no force that will be able to protect them from the retribution of the Serb people, so let them guide themselves in accordance with that" and announced that after the "liquidation of communists, they will be able to liquidate the Ustaša". On 14–15 October, the Chetniks, acting on their own, massacred over five hundred Croats and Muslims and burnt numerous villages in the process of the operation on the suspicion that they "harbored and aided the Partisans". According to the historian Jozo Tomasevich, incomplete data shows 543 civilians were massacred.
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The fault line was thought to be inactive, but in February 2007, a study by the U.S. Army Corps of Engineers found evidence of at least one earthquake in the last 5,000 years, and therefore judged the fault line as active. With the new information about the fault line, the study said the dam was not likely to be in danger.KERO 23, Fault Beneath Isabella Dam Active, February 28, 2007 On November 9, 2007, the Corps of Engineers released the Isabella Dam Consensus Report, that confirmed the high-risk classification of the dam, ranking Isabella Dam among the 6 highest risk and highest priority dams in America,U.S. Army Corps of Engineers, Corps of Engineers Releases External Review Report on Isabella Dam, Release No. PA-07-14, November 9, 2007 and later elevated it to the highest priority.
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The Kern Canyon Fault (Late-Quaternary Active Kern Canyon Fault) is a dextral strike-slip fault (horizontal) that runs roughly around 150 km (93 mi) beside the Kern Canyon River through the mountainous area of the Southern Sierra Nevada Batholith. The fault was a reverse fault in the Early Cretaceous epoch during the primal stages of the Farallon Plate subduction beneath the North American Continental Plate and fully transitioned into a strike-slip shear zone during the Late Cretaceous. Professor Robert W. Webb of the University of Chicago was the first to research the fault in 1936; He found a lava flow (Pliocene age) that covered the northern end of the fault trace where the Little Kern and Kern River coincided. Without any evidence of deformation affecting the hardened lava and without any evidence found previously when investigating the fault line, Webb deemed the fault to be inactive.
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The Royal Naval Patrol Service has its origins in the Great War when the threat of mine warfare was first realized by the British Admiralty. The pre-war Commander-in- Chief of the Home Fleet, Admiral Lord Charles Beresford, is credited with recommending the use of Grimsby trawlers for minesweeping operations following visits he made to various East Coast Ports in 1907. Grimsby, with its impressive docklands and trawler fleet was seen as ideal, with the Commander- in-Chief arguing that the fishing fleet would be inactive in times of war as fishing grounds became war zones.Ministry of Information, His Majesty's Minesweepers, London: His Majesty's Stationery Office, 1943 It was also thought that trawlermen would be more skilled than naval ratings with regards to the handling of the sizeable warps and winches that would be required for mine sweeping as they were already accustomed to using them with the working of the trawl.
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Grimsby, with its impressive docklands and trawler fleet was seen as ideal, with Beresford arguing that the fishing fleet would be inactive during times of war as fishing grounds became war zones.Ministry of Information, His Majesty's Minesweepers, London: His Majesty's Stationery Office, 1943 It was also thought that trawlermen would be more skilled than naval ratings with regards to the handling of the sizeable warps and winches that would be required for minesweeping as they were already accustomed to using them with the working of the trawl. In the First World War the boats provided the craft, the trawler fleet the crew, and the port a base for the Royal Naval Patrol Service. It was noted that his personality seemed to have changed for the worse, and historians have suggested that he might have suffered a minor stroke at some time before 1907. In 1907 and 1908, there were two incidents involving Admiral Percy Scott, commander of the First Cruiser Division of the Channel Fleet. In November 1907, Beresford ordered all ships of the Channel Fleet then at sea to return to harbour to be repainted for a review by the Kaiser.
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Sydnor was highly critical of Irving's unreferenced statement that the Jews who fought in the Warsaw Ghetto Uprising of 1943 were well supplied with weapons from Germany's allies.Sydnor, Charles "The Selling of Adolf Hitler: David Irving's Hitler's War" pages 169–99 from Central European History Issue # 2, Volume 12, June 1979 pages 179. In the same light, concerning Irving's claim that Hitler was ignorant of the Holocaust prior to October 1943, Sydnor commented that Hitler had received a SS report in November 1942 which contained a mention of 363,211 Russian Jews executed by the Einsatzgruppen between August–November 1942.Syndnor, Charles "The Selling of Adolf Hitler: David Irving's Hitler's War" pages 169–99 from Central European History Issue # 2, Volume 12, June 1979 pages 182–183. Similarly, Sydnor charged Irving with misquotation such as having Hitler say on 25 October 1941 "with the Jews too I've found myself remaining inactive", thereby implying that Hitler wanted to be "inactive" against the Jews for the rest of the war, when the documents show Hitler's remarks to be "Even with regard to the Jews I've found myself remaining inactive", and that Hitler's remark was referring to the past when Hitler was criticising himself for his past "inactivity" against the Jews.
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On December 19, 2007, during the first quarter of the game versus the Atlanta Hawks while getting back on a fast-break, Alonzo Mourning tore the patellar tendon in his right knee and was required to undergo season-ending knee surgery. On February 5, 2008, ESPN reported that the Heat were interested in trading center Shaquille O'Neal, contrary to reports by Pat Riley one month earlier that the Heat was not interested in trading the 13-time all-star. The next day however, the Heat agreed to trade O'Neal to the Phoenix Suns for Shawn Marion and Marcus Banks, effectively ending the Wade-O'Neal era. The Heat clinched the worst record in the NBA at 15–67 (.183). Late in the season, with the Heat well out of any type of realistic playoff contention, head coach Pat Riley missed two games because he went to scout certain NCAA basketball conference tournament games, to prepare in the likely event that the Heat received the number 1 or 2 pick in the 2008 draft. It was announced on March 10, 2008, that Heat guard Dwyane Wade would be inactive for the rest of the season to help him rehabilitate his ailing knee and shoulder that he had re- aggravated, in hopes of playing in the 2008 Olympic Games in Beijing.
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